Genome Clustering - Pathway Enrichment Analysis - GO Terms
Matthew Berginski
22 May, 2020
This preliminary report details the results of looking for pathway enrichment in each of the groups of genes produced by hierarchical clustering of the drug perturbations. I’ve cut the the data into 20, but this value can be changed if we decide on a different value. Otherwise, this analysis focuses on enriched pathways in the KEGG database. Specifically, this analysis uses the GO Biological Processes segment from: https://www.gsea-msigdb.org/gsea/msigdb.
As for this report, the panel on the left is sorted by the number of dark kinases in the cluster and displays both the number of pathway hits and dark kinases in the cluster. The number of each cluster is arbitrary. The entry for each cluster displays the kinases associated with the cluster along with the number of non-kinases genes. Below this table are the pathways that passed the enrichment analysis at the 0.01 false discovery rate level. I also corrected for running this analysis for all 20 clusters.
Num: 12 (Pathways: 769 DK: 19)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (19) | CAMK1D, CAMKV, CDKL3, DYRK1B, LMTK2, LMTK3, MAP3K15, MAPK15, MARK1, MKNK1, NEK5, PIK3C2B, PIP5K1B, SBK1, SCYL2, STK3, TESK2, TSSK1B, VRK3 |
| Light Kinase (46) | ACVR1C, ACVR2A, ACVRL1, ANKK1, BMP2K, BMX, CAMK2B, CAMK4, CDK9, CSF1R, DAPK1, DAPK2, DCLK1, EPHA6, EPHB2, EPHB3, FGFR1, FGFR2, FGFR3, FGFR4, FLT4, HCK, ITK, JAK2, KALRN, KSR1, KSR2, MAP2K3, MAP2K6, MAP4K1, MAPK10, MAPK11, MAST1, MATK, PI4KAP2, PRKCG, PRKCZ, PRKD2, PTK2, RPS6KA3, SGK2, SRPK2, STK26, STYK1, TAF1L, TXK |
| Non-kinase Count | 1748 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 1625 | 226 | ADAM22,ADGRB3,AHI1,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ARHGEF10,ASTN1,ATOH1,ATP2B2,ATP8A2,B4GALT5,BACE2,BCL11A,BICDL1,BMERB1,BMP6,BOC,BRINP1,BRINP2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CAMSAP3,CD38,CDH1,CDH2,CDK5R2,CDKL3,CEND1,CHODL,CHRNA7,CHRNB2,CLMN,CLU,CNGB1,CNTN1,CPEB3,CRB1,CRMP1,CSF1R,CSPG5,CX3CR1,CYFIP2,DCC,DCDC2,DCLK1,DISP3,DLL4,DOK5,DPYSL3,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,EML1,ENAH,EOMES,EPHA6,EPHB2,EPHB3,EXT1,FA2H,FBXO31,FGFR1,FGFR2,FKBP1B,FOXA1,FPR2,FZD9,GABRB2,GCM1,GDF6,GFRA2,GNAO1,GNAT2,GPC2,GPR37L1,GPRC5B,GRB2,GRIN1,HAP1,HES2,HEY2,HEYL,HS6ST1,IFT20,IGSF9,IL1RAPL1,IL33,IL34,IRX5,ISLR2,IST1,ITGA6,ITM2C,JAK2,JAM3,JUN,KALRN,KDM1A,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LHX6,LIN28A,LINGO1,LLPH,LMX1B,LRP6,LRRC4C,LZTS1,MAGI2,MAP1S,MAP6,MAPK8IP2,MARK1,MDGA1,METTL14,MMD,MNX1,MYCL,MYLIP,MYRF,NCAM1,NCK2,NCKAP1L,NDNF,NEDD4L,NEO1,NEURL1,NEUROG2,NFASC,NFATC4,NGFR,NKD1,NKX2-1,NKX6-1,NOS1,NOTCH3,NR2F1,NRN1L,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,NYAP2,OLFM1,OPCML,P2RY1,PCDH12,PITX2,PLP1,PLPPR4,POMGNT2,POSTN,POU4F1,POU4F3,PRDM6,PREX2,PRKCZ,PSD,PTK2,PTPRZ1,RAB17,RAB29,RAP1GAP,RARB,RASGRF1,RGMA,RITA1,RND2,ROBO1,RORB,RTN4RL2,RUNX3,S100A9,S1PR5,SAMD14,SCRIB,SDK2,SEMA4D,SEMA5B,SEMA7A,SH3TC2,SHTN1,SLC4A10,SLC6A4,SLIT1,SLIT3,SLITRK2,SLITRK3,SMARCA1,SOX4,SOX6,SPINT1,SPTA1,SPTAN1,SPTB,SRCIN1,SRRM4,STK3,STMND1,SYT2,TENM1,TMEFF2,TMEM30A,TRPV2,TSPAN2,TUBB2A,UGCG,UGT8,UNC5B,USH2A,WASF3,XK,ZFYVE27,ZNF521 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 1665 | 228 | ABCC8,ABHD6,ACHE,ACVR1C,ADRA1A,ALS2,AMER2,ANKRD6,ANXA9,APC2,ARL6,ASIC1,ATP6V1C2,BCL9,BICC1,BMP6,BMP8A,BTRC,CACNA1G,CACNA2D1,CACNA2D2,CACNB2,CALB2,CAMK2B,CASR,CCL26,CCN3,CD34,CD38,CD70,CDH1,CDH2,CDH3,CDHR3,CELF4,CHRFAM7A,CHRM4,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CHST4,CLSTN3,CNIH2,CPEB3,CPLX1,CPT1A,CPZ,CRB1,CSPG5,CX3CR1,CYB5R4,CYP46A1,DACT3,DCC,DCDC2,DHH,DOC2B,DRAXIN,DRD2,DRD4,EDA,EFNA2,EGR2,EIF4A3,ENHO,EPHB2,FAM3B,FCHSD1,FFAR2,FGF14,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGG,FKBP1B,FOXA1,FZD9,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GAD1,GDF9,GLI1,GLRA3,GLS,GNAO1,GNAT2,GPRC5B,GRB2,GREM1,GRID1,GRIK4,GRIK5,GRIN1,GRM7,GSKIP,GUCA1B,GUCY1A1,GUCY1B1,HAP1,HCN2,HCN4,HNF4A,HTR2A,HTR3A,HTR3B,IAPP,IFT20,IFT80,IGFBP2,IGSF11,IL11,IL1RAPL1,IL7,ILDR1,ILDR2,INHBB,INSL4,INSYN1,ITGAM,JAK2,KALRN,KCND2,KCNE5,KCNJ11,KCNJ5,KCNMB1,KCNN1,KCNN2,KIF5A,KLF5,KPNA1,LGMN,LGR5,LRP6,LRRC4C,LZTS1,MAFA,MAGI2,MAPK8IP1,MAPK8IP2,MARK1,MBP,MCTP2,MESD,NDRG2,NEURL1,NFATC4,NKD1,NKX3-1,NKX6-1,NOS1,NOS2,NRXN1,NRXN2,NTNG2,NXN,OPRK1,P2RX7,P2RY1,PCSK5,PLAT,PLCL2,PLP1,PMCHL2,PRKAR2B,PRKCG,PRKCZ,PSMD9,PTPRN2,RAB3B,RASGRF1,RGS10,RIC3,RIMBP2,RIMS3,RNF216,RNF43,RPH3A,S100A9,SCEL,SCN3B,SCN4B,SCN5A,SCRIB,SCYL2,SH2D1A,SHISA2,SIRT4,SLC16A10,SLC16A2,SLC17A8,SLC18A2,SLC1A4,SLC1A6,SLC29A1,SLC4A10,SLC6A1,SLC6A4,SOSTDC1,SOX4,SRD5A2,STAB1,STK3,STX11,STX1A,SULF2,SV2B,SYBU,SYN3,SYP,SYT2,SYT5,TCF7,TCF7L1,TLE3,TNFSF10,TRIM9,TSPAN12,VIPR2,VSNL1,ZNF703 |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 1365 | 196 | ADGRB3,AHI1,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP2B2,ATP8A2,B4GALT5,BCL11A,BICDL1,BMP6,BOC,BRINP1,BRINP2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CAMSAP3,CD38,CDH1,CDH2,CDKL3,CEND1,CHODL,CHRNA7,CHRNB2,CLMN,CNGB1,CNTN1,CPEB3,CRB1,CRMP1,CSF1R,CYFIP2,DCC,DCDC2,DCLK1,DISP3,DLL4,DOK5,DPYSL3,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EOMES,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGFR1,FGFR2,FKBP1B,FOXA1,GABRB2,GDF6,GFRA2,GNAO1,GNAT2,GPC2,GPR37L1,GPRC5B,GRB2,GRIN1,HEY2,HEYL,HS6ST1,IFT20,IGSF9,IL1RAPL1,IRX5,ISLR2,IST1,ITGA6,ITM2C,JAK2,JAM3,JUN,KALRN,KDM1A,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LHX6,LIN28A,LINGO1,LLPH,LMX1B,LRP6,LRRC4C,LZTS1,MAGI2,MAP1S,MAP6,MAPK8IP2,MARK1,MDGA1,MMD,MNX1,MYCL,MYLIP,NCAM1,NCK2,NCKAP1L,NDNF,NEDD4L,NEO1,NEURL1,NEUROG2,NFASC,NFATC4,NGFR,NKD1,NKX2-1,NKX6-1,NOTCH3,NR2F1,NRN1L,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,NYAP2,OLFM1,OPCML,PCDH12,PITX2,PLP1,PLPPR4,POSTN,POU4F1,POU4F3,PREX2,PRKCZ,PSD,PTK2,PTPRZ1,RAB17,RAB29,RAP1GAP,RARB,RASGRF1,RGMA,RND2,ROBO1,RORB,RTN4RL2,RUNX3,S100A9,S1PR5,SAMD14,SCRIB,SDK2,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLC4A10,SLC6A4,SLIT1,SLIT3,SLITRK2,SLITRK3,SMARCA1,SOX4,SPTA1,SPTAN1,SPTB,SRCIN1,SRRM4,STK3,STMND1,SYT2,TENM1,TMEFF2,TMEM30A,TRPV2,TSPAN2,UGCG,UGT8,UNC5B,USH2A,XK,ZFYVE27,ZNF521 |
| GO_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 1692 | 214 | ABCB1,ABCC1,ABCC8,ACE,ACTN2,ADCYAP1R1,ADRA1A,AKAP6,AMIGO1,ANO3,ANO9,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,ATP8A2,AVPR1A,CA6,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CAMK2B,CASR,CEACAM1,CHRFAM7A,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CLCA3P,CLCN4,CLDN10,CLIC5,CNGA1,CNGB1,CNIH2,CNTN1,CORO1A,COX7B2,CPLX1,CPT1A,CYB5R1,CYB5R4,CYBB,DAPK1,DRD2,DRD4,EPHB2,FAM155A,FGF14,FGFR1,FKBP1B,FXYD7,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GEM,GLRA3,GLS,GLS2,GNAO1,GRID1,GRIK4,GRIK5,GRIN1,GRM7,HAP1,HBA1,HCN2,HCN4,HTR2A,HTR3A,HTR3B,HVCN1,IL16,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,LILRA2,LMTK2,LRRC8C,LRRC8E,LTF,MAGT1,MAP2K6,MAPK15,MAPK8IP2,MRLN,NEDD4L,NIPAL1,NKAIN1,NMUR1,NOS1,NOS1AP,NOS2,NOX5,OPRD1,P2RX7,P2RY1,PKD1L2,PLA2G2D,PLA2G4A,PLCD1,PLCH1,PLCL2,PLLP,PTAFR,PTPN3,RAB3B,RASGRF1,RGN,RGS9,RTBDN,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SGK2,SLC12A8,SLC13A3,SLC15A1,SLC16A10,SLC16A2,SLC16A5,SLC17A8,SLC18A2,SLC1A4,SLC1A6,SLC22A11,SLC22A23,SLC24A4,SLC25A27,SLC27A6,SLC2A12,SLC30A10,SLC30A3,SLC36A2,SLC36A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC52A3,SLC5A5,SLC66A2,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,SLC6A4,SLC9B1,SLCO2B1,SLN,STX1A,SYT13,SYT2,SYT5,TESC,TMC5,TMC6,TMC7,TMEM30A,TRPA1,TRPM8,TRPV2,TRPV3,TTYH2,TUSC3,XK,XKR4,XKR5,XPR1,ZDHHC13 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 1545 | 199 | ACTN2,ADGRB3,AHI1,AK7,AKIRIN1,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ARL6,ATOH1,ATP1A3,ATP8A2,B4GALT5,BCL11A,BICDL1,BOC,C21orf91,CACNG7,CAMK1D,CAMK2B,CAMSAP3,CD38,CDC14A,CDH1,CDH2,CDKL3,CEP19,CEP83,CFAP53,CFAP61,CHODL,CHRNA7,CHRNB2,CLMN,CNTN1,CORO1A,CPEB3,CRMP1,CSF1R,CSPG5,CYFIP2,DCC,DCDC2,DCLK1,DNAAF3,DNAH7,DNAI1,DOK5,DPYSL3,DPYSL5,DRAXIN,DRD2,DYNLL1,EFNA2,EGR2,EMP2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGD2,FGD5,FGFR1,FGFR2,FKBP1B,GFRA2,GFY,GNAO1,GPC2,GRB2,GRIN1,HAP1,HYDIN,IFT20,IFT80,IGSF9,IL1RAPL1,IQUB,ISLR2,IST1,ITGA6,ITM2C,JAK2,JAM3,JHY,JUN,KALRN,KCTD17,KDM1A,KIF13B,KIF27,KIF5A,KIF5C,KLF5,KNDC1,LGMN,LHX4,LINGO1,LLPH,LRGUK,LRRC4C,LZTS1,MAGI2,MAP1S,MAP6,MAPK15,MAPK8IP2,MARK1,MNX1,MYLIP,MYO10,NCAM1,NCK2,NCKAP1L,NDNF,NECTIN2,NEDD4L,NEO1,NES,NEURL1,NFASC,NFATC4,NGFR,NKX2-1,NKX6-1,NR2F1,NRN1L,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,NYAP2,OLFM1,P2RX7,PLP1,PLPPR4,PLS1,PODXL,POSTN,POU4F1,POU4F3,PPP1R16B,PREX2,PRKAR2B,PRKCZ,PSD,PTK2,PTPRZ1,RAB17,RAB29,RAP1GAP,RASGRF1,RGMA,RHOV,RND2,ROBO1,RTN4RL2,S100A9,SAMD14,SCRIB,SEMA4D,SEMA5B,SEMA7A,SEPTIN6,SFI1,SHTN1,SLIT1,SLIT3,SLITRK2,SLITRK3,SNX2,SPTA1,SPTAN1,SPTB,SRCIN1,STK26,STK3,STMND1,SYT2,TBC1D30,TEKT1,TENM1,TMEFF2,TMEM30A,TRPV2,TSPAN2,TUB,TUBB4A,UGT8,UNC5B,WAS,WASF3,XK,ZFYVE27 |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 1425 | 189 | ACER2,ACHE,ACTN2,ACVRL1,ADAM22,ADAM23,ADD2,ADGRE1,ADGRL1,ALOX15,AMIGO1,ANXA9,ARHGAP6,ASTN1,ATP1B1,ATP1B2,AZGP1,BCL2L11,BMP6,BMX,BOC,BTN2A2,CADM2,CADM4,CALR,CAMSAP3,CARD11,CCN3,CD1D,CD209,CD22,CD34,CD6,CD70,CD74,CD83,CD86,CDH1,CDH15,CDH2,CDH3,CDHR3,CDKN2A,CEACAM1,CHRD,CHST4,CLDN10,CLDN23,CLSTN3,CNN3,CNTN1,CNTNAP3B,CNTNAP5,COL19A1,COL4A3,COL5A3,COMP,CORO1A,CRB1,CRISP2,CSPG5,CX3CR1,CYFIP2,DOCK8,DSC2,DSC3,DSG3,DUSP1,DUSP26,EDA,ELMO2,EMILIN2,EMP2,EPB41L5,EPDR1,EPHB3,ESAM,FGG,FGL1,FOXA1,FPR2,FREM2,FYB2,GRB2,GREM1,HAVCR2,HCK,HHLA2,HLA-DPB1,HLX,ICAM2,IGFBP2,IGSF11,IGSF5,IGSF9,IL12A,IL1RAPL1,IL23R,IL7,INHBB,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,IZUMO1,JAK2,JAM3,KIF26B,KIRREL2,KNG1,LAMA4,LRFN5,LRP6,LRRC15,LRRC4C,LRRN2,LTF,LY9,LYPD5,MBP,MDGA1,MIA3,MYO10,MYO1G,NCAM1,NCK2,NCKAP1L,NDNF,NECTIN2,NEO1,NFASC,NRP2,NRXN1,NRXN2,NRXN3,NTN1,NTNG2,OPCML,OTOA,PCDH10,PCDH12,PCDH20,PCDHA10,PCDHA4,PCDHA5,PCDHGA3,PELI1,PLA2G2D,PODXL,POSTN,PRKCZ,PRKD2,PSTPIP1,PTAFR,PTK2,RADIL,ROBO1,RUNX3,S100A9,SCRIB,SDK2,SELL,SELPLG,SEMA4D,SH2B3,SIGLEC11,SIGLEC14,SIGLEC8,SLAMF7,SLITRK2,SLITRK3,SPN,SPOCK2,SPTA1,SRCIN1,STAB1,SYMPK,TENM1,TESC,TESK2,TESPA1,THEMIS2,TRO,VAV1,VCAN,VMP1,VWA2,ZNF703 |
| GO_NEURON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 1114 | 163 | ADGRB3,AHI1,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,B4GALT5,BCL11A,BICDL1,BOC,C21orf91,CACNG7,CAMK1D,CAMK2B,CAMSAP3,CD38,CDH1,CDH2,CDKL3,CHODL,CHRNA7,CHRNB2,CLMN,CNGB1,CNTN1,CPEB3,CRB1,CRMP1,CSF1R,CYFIP2,DCC,DCDC2,DCLK1,DOK5,DPYSL3,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGFR1,FGFR2,FKBP1B,GABRB2,GFRA2,GNAO1,GNAT2,GPC2,GRB2,GRIN1,HS6ST1,IFT20,IGSF9,IL1RAPL1,IRX5,ISLR2,IST1,ITGA6,ITM2C,JAK2,JAM3,JUN,KALRN,KDM1A,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LHX6,LINGO1,LLPH,LRRC4C,LZTS1,MAGI2,MAP1S,MAP6,MAPK8IP2,MARK1,MNX1,MYLIP,NCAM1,NCK2,NCKAP1L,NDNF,NEDD4L,NEO1,NEURL1,NFASC,NFATC4,NGFR,NKX2-1,NKX6-1,NR2F1,NRN1L,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,NYAP2,OLFM1,OPCML,PCDH12,PLP1,PLPPR4,POSTN,POU4F1,POU4F3,PREX2,PRKCZ,PSD,PTK2,PTPRZ1,RAB17,RAB29,RAP1GAP,RASGRF1,RGMA,RND2,ROBO1,RORB,RTN4RL2,RUNX3,S100A9,SAMD14,SCRIB,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLC4A10,SLIT1,SLIT3,SLITRK2,SLITRK3,SPTA1,SPTAN1,SPTB,SRCIN1,SRRM4,STK3,STMND1,SYT2,TENM1,TMEFF2,TMEM30A,TRPV2,TSPAN2,UGCG,UGT8,UNC5B,XK,ZFYVE27 |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 1894 | 215 | ABCB1,ABCC8,ACHE,ACTN2,ACVR1C,ADCYAP1R1,ADRA1A,AHI1,AKAP6,ALOX15,AMIGO1,ANO9,ANXA9,ARHGAP44,ASIC1,ATP1B1,ATP1B2,ATP8A2,AVPR1A,AZIN2,BMP2K,BMP6,BMP8A,BTN2A2,C5,CABP1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CALR,CAMK1D,CAMK2B,CASR,CBL,CCN3,CD22,CD34,CD38,CD40,CD74,CDH1,CDH2,CDH3,CDK5R2,CEACAM1,CHP2,CHRNB2,CHRNB4,CLCA3P,CLDN10,CLEC7A,CLIC5,CLU,CNIH2,CNTN1,CORIN,CORO1A,CPLX1,CPT1A,CRTAM,CSF1R,CSPG5,CTTNBP2NL,CYBB,DAPK1,DISP1,DISP3,DMAP1,DNAJC1,DOC2B,DRD2,DRD4,ENHO,EPHB2,FCN1,FFAR2,FGF14,FGF21,FGFR1,FGG,FKBP1B,FPR2,FXYD7,FZD9,GDF9,GEM,GNAO1,GPR143,GREM1,GRIK5,GRIN1,GRM7,HAP1,HAVCR2,HCK,HCN2,HCN4,HNF4A,HTR2A,HTR3A,HUWE1,HVCN1,IL11,IL16,IL1R2,IL1RAPL1,IL2RB,IL33,ILDR1,INHBB,ITGAM,JAK2,KALRN,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNMB1,KCNN2,KCNQ4,KCNV1,LGI3,LILRA2,MAGI2,MAP2K6,MAPK11,MAPK15,MAPK8IP1,MAPK8IP2,MBP,MCTP2,MRLN,NCKAP1L,NEDD4L,NKAIN1,NKX3-1,NKX6-1,NOS1,NOS1AP,NOS2,NOX5,NRXN1,OAZ2,OPRD1,OPRK1,P2RX7,P2RY1,PAEP,POSTN,PRKCG,PRKCZ,PSMD9,PTAFR,PTGER4,PTPN3,RAB29,RAB3B,RASGRF1,REEP1,RGN,RGS9,RIMS3,SCAMP5,SCFD1,SCIN,SCN3A,SCN3B,SCN4B,SCN5A,SCRIB,SCYL2,SEPTIN4,SGK2,SH3TC2,SIRT4,SLC25A27,SLC2A4,SLC30A10,SLC30A3,SLC6A1,SLC6A4,SLN,SOX4,SRCIN1,STX1A,SYBU,SYP,SYT13,SYT2,SYT5,TENM1,TESC,TLR10,TLR5,TMEM30A,TRIM9,TRPV2,TRPV3,TUB,VSNL1 |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 1604 | 194 | ABCA5,ABCB1,ABCB9,ABCC1,ABCC8,ABCG4,ACTN2,ADD2,AKAP6,AMIGO1,ANO3,ANO9,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,AZGP1,AZIN2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CASR,CHRFAM7A,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CLCA3P,CLCN4,CLIC5,CLU,CNGA1,CNGB1,CNIH2,CORO1A,COX7B2,CPT1A,CTTNBP2NL,CYBB,DAPK1,DRD2,DRD4,EPHB2,FAM155A,FGF14,FGF21,FKBP1B,FXYD7,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GEM,GJA3,GLRA3,GRID1,GRIK4,GRIK5,GRIN1,HAP1,HCN2,HCN4,HTR2A,HTR3A,HTR3B,HVCN1,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,LRRC8C,LRRC8E,MAGT1,MAPK8IP2,MRLN,NEDD4L,NIPAL1,NOS1,NOS1AP,NOX5,OAZ2,P2RX7,PEX5L,PKD1L2,PLCD1,PLCH1,PLCL2,PSMD9,PTAFR,PTPN3,RASGRF1,RGN,RGS9,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SGK2,SLC12A8,SLC13A3,SLC15A1,SLC16A10,SLC16A2,SLC16A5,SLC17A8,SLC18A2,SLC1A4,SLC1A6,SLC22A11,SLC22A23,SLC23A3,SLC24A4,SLC25A27,SLC25A44,SLC28A2,SLC29A1,SLC29A4,SLC2A12,SLC2A4,SLC30A10,SLC30A3,SLC36A2,SLC36A3,SLC40A1,SLC44A3,SLC4A10,SLC4A5,SLC4A8,SLC5A5,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,SLC6A4,SLC9B1,SLCO2B1,SLN,SPNS2,SV2B,SVOP,TESC,TMC5,TMC6,TMC7,TMEM150C,TMEM241,TMEM30A,TRPA1,TRPM8,TRPV2,TRPV3,TTYH2,TUSC3,XPR1,ZDHHC13 |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 1160 | 157 | ABCB1,ABCC1,ABCC8,ACTN2,AKAP6,AMIGO1,ANO3,ANO9,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CASR,CHRFAM7A,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CLCA3P,CLCN4,CLIC5,CNGA1,CNGB1,CNIH2,CORO1A,COX7B2,CPT1A,CYBB,DAPK1,DRD2,DRD4,EPHB2,FAM155A,FGF14,FKBP1B,FXYD7,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GEM,GLRA3,GRID1,GRIK4,GRIK5,GRIN1,HAP1,HCN2,HCN4,HTR2A,HTR3A,HTR3B,HVCN1,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,LRRC8C,LRRC8E,MAGT1,MAPK8IP2,MRLN,NEDD4L,NIPAL1,NOS1,NOS1AP,NOX5,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,PTAFR,PTPN3,RASGRF1,RGN,RGS9,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SGK2,SLC12A8,SLC13A3,SLC15A1,SLC16A10,SLC17A8,SLC1A4,SLC1A6,SLC24A4,SLC25A27,SLC2A12,SLC30A10,SLC30A3,SLC36A2,SLC36A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC6A12,SLC6A14,SLC9B1,SLN,TESC,TMC5,TMC6,TMC7,TRPA1,TRPM8,TRPV2,TRPV3,TTYH2,TUSC3,XPR1,ZDHHC13 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1825 | 196 | ACHE,ACVR2A,ACVRL1,ADGRB2,ADGRB3,ADGRL1,ADRA1A,AFAP1L2,AKAP6,AMIGO1,ANXA9,ATOH1,ATP8A2,AVPR1A,B4GALT5,BMP6,BRINP1,BRINP2,BTN2A2,C21orf91,C5,CACNA2D2,CACNG7,CALR,CAMK1D,CAMK2B,CARD11,CASR,CBLN2,CCR6,CD34,CD38,CD40,CD6,CD74,CD83,CD86,CDK9,CDKL3,CEACAM1,CEBPA,CHODL,CHRNA7,CHRNB4,CLEC7A,CLSTN3,CLU,CNTN1,CPEB3,CRTAM,CSF1R,CST7,CX3CR1,CXCR2,CYBB,CYP26B1,DMRT1,DPYSL3,DRD2,EBF2,EPB41L5,EPHB2,EPHB3,ESRRB,FBXO31,FCN1,FFAR2,FGF18,FGF21,FGFR1,FGFR2,FGG,FKBP1B,FLT4,FOXA1,FZD9,GBP5,GDF6,GHR,GLI1,GPC2,GPR37L1,GPRC5B,GREM1,GRIN1,HAP1,HAVCR2,HEY2,HEYL,HHLA2,HLA-DPB1,HLX,HTR2A,IGSF11,IL12A,IL1RAPL1,IL23R,IL33,IL34,IL7,INHBB,ISLR2,IST1,ITGA6,ITGAX,JAK2,JUN,KALRN,KDM1A,KSR2,LGMN,LILRA2,LIN28A,LLPH,LTF,LY9,MAGI2,MAP2K3,MAP6,MAPK11,MBP,MMD,MSX2,MYRF,NCKAP1L,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX3-1,NKX6-1,NOS1,NOS1AP,NRP2,NRXN1,NTN1,OLFM1,P2RX7,P2RY1,PAEP,PELI1,PLS1,POLR3A,POSTN,POU4F1,PPP1R16B,PRKCZ,PRKD2,PTAFR,PTGER4,PTGIS,PTK2,PTPRZ1,RAET1G,RARB,RBM24,RND2,RNF125,ROBO1,RUNX3,S100A9,SCAMP5,SCIMP,SCIN,SCN3B,SEMA4D,SEMA7A,SERPINB7,SHTN1,SLITRK2,SLITRK3,SLN,SNAI1,SOX6,SPINT1,SPN,STX1A,SULF2,SYT2,TESC,TESPA1,TLR5,TLR7,TMEM100,TMEM30A,TNFRSF8,TRPM8,TRPV2,TXK,VASH2,WASF3,ZBTB46,ZFYVE27,ZNF322,ZNF703 |
| GO_SYNAPTIC_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 733 | 117 | ABHD6,ACHE,ADRA1A,ALS2,ANXA9,ASIC1,CACNA1G,CACNA2D2,CACNB2,CALB2,CAMK2B,CD38,CDH1,CDH2,CDHR3,CELF4,CHRFAM7A,CHRM4,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CLSTN3,CNIH2,CPEB3,CPLX1,CSPG5,CX3CR1,CYP46A1,DCC,DOC2B,DRD2,DRD4,EGR2,EIF4A3,EPHB2,FCHSD1,FGF14,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GAD1,GLRA3,GLS,GRID1,GRIK4,GRIK5,GRIN1,GRM7,GUCY1A1,GUCY1B1,HAP1,HTR2A,HTR3A,HTR3B,IGSF11,IL1RAPL1,INSYN1,JAK2,KCND2,KCNMB1,KCNN1,KIF5A,KPNA1,LGMN,LRP6,LRRC4C,LZTS1,MAPK8IP2,MBP,MCTP2,NEURL1,NFATC4,NOS1,NRXN1,NRXN2,NTNG2,OPRK1,P2RX7,P2RY1,PLAT,PLCL2,PLP1,PMCHL2,PRKAR2B,PRKCG,PRKCZ,PTPRN2,RAB3B,RASGRF1,RGS10,RIC3,RIMBP2,RIMS3,RNF216,RPH3A,SCRIB,SLC17A8,SLC18A2,SLC1A4,SLC1A6,SLC29A1,SLC4A10,SLC6A1,SLC6A4,STX11,STX1A,SV2B,SYBU,SYN3,SYP,SYT2,SYT5,TRIM9 |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 1680 | 183 | ABCC8,ACE,ACHE,ACTN2,ACVR1C,ADA2,ADRA1A,AOC1,ARHGAP44,ARHGAP9,ASIC1,AVPR1A,BMP6,BMP8A,BTN2A2,C5,CACNA1G,CACNA1I,CACNA2D2,CACNB2,CARD11,CASR,CBL,CCN3,CD22,CD34,CD38,CD40,CD74,CDK5R2,CEACAM1,CHRNB2,CHRNB4,CLU,COMP,CORIN,CORO1A,CPLX1,CPT1A,CRTAM,CSF1R,CSPG5,CXCR2,CYB5R1,CYB5R4,CYBB,DISP1,DNAJC1,DOC2B,DRD2,DRD4,DYNLL1,ENDOD1,ENHO,EXOC8,F5,FAM3B,FCN1,FFAR2,FGFR1,FGG,FKBP1B,FPR2,FRMPD3,GAD1,GBP5,GCA,GDF9,GLS,GLS2,GOLGA7,GPAT4,GRIK5,GRM7,GUCA1B,HAP1,HAVCR2,HCK,HNF4A,HP,HTR2A,HUWE1,HVCN1,IL11,IL1R2,IL1RAPL1,IL33,ILDR1,ILDR2,INHBB,IST1,ITGAL,ITGAM,ITGAX,JAK2,JHY,KALRN,KCNJ11,KNG1,LAIR1,LGI3,LILRA2,LTF,MAFA,MAGT1,MAP2K6,MAPK11,MBP,MCTP2,MGAM,MIA3,MYO1G,NCKAP1L,NEURL1,NFASC,NKX3-1,NKX6-1,NOS2,NOX5,NRXN1,NRXN2,OLFM2,OPRK1,ORMDL3,P2RX7,P2RY1,PAEP,PCSK5,PIGR,PLA2G2D,PLA2G4A,POSTN,PRKCG,PRKCZ,PSMD9,PTAFR,PTGER4,PTPRN2,PYGL,RAB37,RAB3B,RAB44,RAB9B,RIMS3,RPH3A,S100A9,SCAMP5,SCFD1,SCG2,SCG3,SCIN,SCRIB,SELL,SEPTIN4,SIGLEC14,SIRT4,SLC16A10,SLC16A2,SLC18A2,SLC1A6,SLC29A1,SLC4A5,SLC6A1,SLC6A4,SOX4,SPTAN1,SRCIN1,STX11,STX1A,SYBU,SYN3,SYP,SYT13,SYT2,SYT5,SYTL5,TIMP3,TLR10,TLR5,TMC6,TMEM30A,TRIM9,VSNL1 |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 1141 | 146 | ACTN2,ADGRB3,ALS2,AMIGO1,ARHGAP15,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,B4GALT5,BCL11A,BOC,CACNG7,CALR,CAMK2B,CDH1,CDH15,CDH2,CDH3,CDHR3,CDKL3,CFL2,CHODL,CHRNA7,CHRNB2,CLU,CORO1A,CRMP1,CSF1R,CSPG5,CYFIP2,DCC,DCDC2,DCLK1,DMRT1,DOK5,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EPB41L5,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGD2,FGD5,FGFR2,FGG,GFRA2,GRB2,GREM1,GRIN1,HCK,IGSF9,IL1RAPL1,ISLR2,IST1,ITGB7,KALRN,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LINGO1,LLPH,LRRC4C,LZTS1,MAP1S,MAP6,MAPK8IP2,MNX1,MYH14,MYL2,MYO10,NCAM1,NCKAP1L,NECTIN2,NEDD4L,NEO1,NES,NFASC,NFATC4,NGFR,NKX2-1,NKX6-1,NOX4,NRN1L,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,NYAP2,OLFM1,P2RX7,P2RY1,PDZD8,PLPPR4,POSTN,POU4F1,POU4F3,PREX2,PRKCZ,PTK2,PTPRZ1,RADIL,RAP1GAP,RHOV,RND2,ROBO1,SCFD1,SCRIB,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SLITRK2,SLITRK3,SNX2,SOX6,SPTA1,SPTAN1,SPTB,SRCIN1,STK3,SYT2,TBPL1,TFCP2L1,TMEFF2,TNNT2,TRPV2,UGT8,UNC5B,VSIG1,VWA2,WASF3,XK,ZFYVE27 |
| GO_CELL_PART_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 691 | 111 | ADGRB3,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,B4GALT5,BCL11A,BOC,CACNG7,CAMK2B,CDH2,CDKL3,CHODL,CHRNA7,CHRNB2,CRMP1,CSF1R,CSPG5,CYFIP2,DCC,DCDC2,DCLK1,DOK5,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGFR2,GFRA2,GRB2,GRIN1,IGSF9,IL1RAPL1,ISLR2,IST1,KALRN,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LINGO1,LLPH,LRRC4C,LZTS1,MAP1S,MAP6,MAPK8IP2,MNX1,MYH14,NCAM1,NCKAP1L,NECTIN2,NEDD4L,NEO1,NES,NFASC,NFATC4,NGFR,NKX2-1,NKX6-1,NRN1L,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,NYAP2,OLFM1,PLPPR4,POSTN,POU4F1,POU4F3,PREX2,PRKCZ,PTK2,PTPRZ1,RAP1GAP,RND2,ROBO1,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SLITRK2,SLITRK3,SNX2,SPTA1,SPTAN1,SPTB,SRCIN1,STK3,SYT2,TMEFF2,TRPV2,UGT8,UNC5B,XK,ZFYVE27 |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 860 | 124 | ABCC8,ACTN2,AKAP6,AMIGO1,ANO3,ANO9,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CASR,CHRNA10,CHRNA7,CLCA3P,CLCN4,CLIC5,CORO1A,COX7B2,DRD2,DRD4,FAM155A,FGF14,FKBP1B,FXYD7,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GEM,GLRA3,GRIN1,HAP1,HCN2,HCN4,HTR2A,HVCN1,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,MAGT1,MRLN,NEDD4L,NIPAL1,NOS1,NOS1AP,NOX5,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,PTAFR,PTPN3,RGN,RGS9,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC12A8,SLC15A1,SLC1A4,SLC24A4,SLC25A27,SLC2A12,SLC30A10,SLC30A3,SLC36A2,SLC36A3,SLC40A1,SLC4A10,SLC9B1,SLN,TESC,TRPA1,TRPM8,TRPV2,TRPV3,TTYH2,TUSC3,XPR1,ZDHHC13 |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 847 | 119 | ADD2,ADGRL1,ALOX15,AMIGO1,ANXA9,ASTN1,BMP6,BTN2A2,CAMSAP3,CARD11,CCN3,CD1D,CD209,CD34,CD6,CD70,CD74,CD83,CD86,CDH1,CDH15,CDH2,CDH3,CDHR3,CEACAM1,CLDN10,CLDN23,CLSTN3,CNN3,COL19A1,COMP,CORO1A,CRB1,CRISP2,CX3CR1,CYFIP2,DOCK8,DSC2,DSC3,DSG3,ELMO2,EPB41L5,EPHB3,ESAM,FGG,FGL1,FOXA1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,ICAM2,IGFBP2,IGSF11,IGSF5,IGSF9,IL12A,IL1RAPL1,IL23R,IL7,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,IZUMO1,JAK2,JAM3,KIF26B,KIRREL2,LRFN5,LRP6,LRRC4C,MBP,MDGA1,MIA3,MYO10,NCK2,NCKAP1L,NECTIN2,NFASC,NRXN1,NRXN2,NRXN3,NTN1,NTNG2,PCDH10,PCDH12,PCDH20,PCDHA10,PCDHA4,PCDHA5,PCDHGA3,PELI1,PLA2G2D,PODXL,PRKCZ,PTAFR,PTK2,ROBO1,RUNX3,S100A9,SCRIB,SDK2,SELL,SELPLG,SEMA4D,SH2B3,SLITRK2,SLITRK3,SPN,SPTA1,TENM1,TESPA1,TRO,VAV1,VMP1,ZNF703 |
| GO_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 1180 | 143 | ABCC8,ACTN2,ADCYAP1R1,ADRA1A,AKAP6,AMIGO1,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CAMK2B,CASR,CHRNA10,CHRNA7,CHRNB2,CLCA3P,CLCN4,CNGA1,CNGB1,CNIH2,CNTN1,CORO1A,COX7B2,DAPK1,DRD2,DRD4,EPHB2,FAM155A,FGF14,FKBP1B,FXYD7,GEM,GNAO1,GRIN1,HAP1,HCN2,HCN4,HTR2A,HVCN1,IL16,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,LILRA2,LMTK2,LTF,MAGT1,MAPK15,MAPK8IP2,MRLN,NEDD4L,NIPAL1,NKAIN1,NMUR1,NOS1,NOS1AP,NOX5,OPRD1,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,PTPN3,RAB3B,RASGRF1,RGN,RGS9,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC12A8,SLC13A3,SLC15A1,SLC17A8,SLC18A2,SLC1A4,SLC24A4,SLC25A27,SLC2A12,SLC30A10,SLC30A3,SLC36A2,SLC36A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC5A5,SLC6A4,SLC9B1,SLN,SYT13,SYT2,SYT5,TESC,TRPA1,TRPM8,TRPV2,TRPV3,TUSC3,ZDHHC13 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1813 | 1781 | 182 | ABCB1,ABHD5,ACE,ACER2,ACTN2,ACVR1C,ADCY4,ADCYAP1R1,ADD2,ADGRB3,ADRA1A,AFAP1L2,AGAP2,AGAP4,AKAP6,ALS2,AMIGO1,ANXA9,APC2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ARRDC4,ATP1B1,ATP1B2,AVPR1A,AZIN2,BCL2L11,C5,CACNA2D1,CACNB2,CAMK1D,CARD11,CASP14,CASR,CCL26,CD40,CD74,CDH3,CDK5R2,CDK9,CHN2,CHP2,CHRNA7,CLEC7A,CLU,COL4A3,CSF1R,CX3CR1,CYFIP2,DAPK1,DEPDC5,DNAJC1,DOCK8,DOK7,DRD2,DRD4,DUSP9,DYNLL1,EBF2,EDA,EMP2,EPB41L5,EPHB2,EVI5,FGD2,FGF14,FGF18,FGFR1,FGFR2,FGFR3,FGFR4,FOXA1,FPR2,GHR,GNAO1,GPR65,GPRC5B,GREM1,GRIN1,GRTP1,GUCA1B,GUCA1C,HAP1,HIGD1A,HTR2A,HTR3A,IL23R,ITGA6,ITGAM,ITK,JAK2,JUN,KALRN,KCNC1,KCNJ11,KDM1A,KSR1,LGMN,LPAR5,LRP6,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK15,MAPRE3,MBP,MMD,MMP16,MUC20,NCKAP1L,NEURL1,NEUROG2,NGFR,NKX3-1,NKX6-1,NMUR1,NOS1,NOS1AP,NOS2,NOX4,OPRD1,P2RX7,PIK3R5,PLCL2,PLIN5,POU4F1,PPM1J,PPP1R3G,PREX2,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTK2,RALGAPB,RAP1GAP,RASGRF1,RGN,RGPD3,RGS10,RGS7,RGS9,ROBO1,S100A9,SCRIB,SEMA4D,SGK2,SGSM1,SGSM3,SPTA1,SRCIN1,SRGAP3,STARD8,STK26,STK3,SYAP1,TACC1,TBC1D1,TBC1D29P,TBC1D30,TENM1,TESC,TIGAR,TNFSF10,TNFSF15,TNNT2,TOR1AIP2,TXK,USP6NL,VAV1,VRK3 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1813 | 1994 | 195 | ACE,ACTN2,ACVR1C,ACVR2A,ACVRL1,ADCY4,ADRA1A,AFAP1L2,ALOX15,ALS2,ANKK1,ANKRD6,ANXA9,BMP2K,BMP6,BMP8A,BMX,BTN2A2,BTRC,C1QL4,C5,CADM4,CAMK1D,CAMK2B,CAMK4,CAMKV,CASR,CBL,CCL26,CD40,CD74,CDH2,CDK5R2,CDK9,CDKL3,CDKN2A,CEACAM1,CEBPA,CHRNA10,CHRNA7,CLU,CNTD2,CNTN1,CRLF1,CSF1R,CX3CR1,DAPK1,DAPK2,DCLK1,DIRAS3,DOK5,DOK7,DRD2,DRD4,DUSP1,DUSP26,DUSP9,DYRK1B,EMP2,EPHA6,EPHB2,EPHB3,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GFRA2,GHR,GPR37,GPR37L1,GPRC5B,GRB2,GREM1,GRIN1,GSKIP,HAVCR2,HCK,HERC5,HIGD1A,HTR2A,IAPP,IL11,IL12A,IL17RD,IL23R,IL2RB,IL34,IL3RA,IL7,INHBB,INHBC,ITK,JAK2,JUN,KALRN,KIRREL2,KLHL31,KNDC1,KSR1,KSR2,LDLRAD4,LMTK2,LMTK3,LRP6,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK15,MAPK8IP1,MAPK8IP2,MAPRE3,MARK1,MAST1,MATK,MBP,MKNK1,MMD,MUC20,NCAM1,NCK2,NCKAP1L,NDRG2,NEK5,NEURL1,NKX3-1,NOS1,NOX4,NPFFR2,NRG2,OPRD1,P2RX7,P2RY1,PIK3R5,PLCL2,PPM1L,PRKAR2B,PRKCG,PRKCZ,PRKD2,PSMD9,PTGER4,PTK2,RASGRF1,RB1CC1,RGN,ROBO1,RPS6KA3,RUNX3,SBK1,SCG2,SCIMP,SCYL2,SEMA4D,SEMA7A,SGK2,SH2B3,SH2D3A,SH2D3C,SH3RF2,SLC30A10,SOCS4,SPTA1,SPTAN1,SPTB,SRCIN1,SRPK2,STK26,STK3,STYK1,SYAP1,TAF1L,TENM1,TESC,TESK2,TIMP3,TLR7,TNFRSF19,TNFSF15,TSSK1B,TXK,VRK3,ZGPAT |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 1881 | 188 | ABCA5,ACVR2A,ACVRL1,ADAMTS20,ADGRB3,AHI1,AKAP6,AKIRIN1,AMIGO1,ANXA9,APC2,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,BCL11A,BMERB1,BMP6,BOC,BRINP1,BRINP2,BTN2A2,C1QL4,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CAMK4,CARD11,CCN3,CD34,CD38,CD74,CD83,CD86,CDH15,CDH2,CDK9,CDKL3,CEACAM1,CEBPA,CHODL,CHRD,CHRNB2,CLEC7A,CNTN1,CPEB3,CRMP1,CSPG5,CX3CR1,CYP26B1,DACT3,DCC,DISP3,DLL4,DPYSL3,DRAXIN,DRD2,EMP2,EPHB2,EPHB3,ESRRB,FBXO31,FGF18,FGFR1,FGFR2,FGG,FKBP1B,FOXA1,FTO,GCM1,GDF6,GLI1,GPC2,GPR37L1,GPRC5B,GREM1,GRHL1,GRIN1,HAP1,HES2,HEY2,HEYL,HLX,HTR2A,IAPP,IL12A,IL1RAPL1,IL23R,IL34,IL7,ISLR2,IST1,ITGA6,ITM2C,JAK2,JUN,KALRN,KDM1A,KIF13B,KLF5,KNDC1,LDLRAD4,LIN28A,LINGO1,LLPH,LRRC4C,LTF,LZTS1,MAGI2,MAP6,MAPK11,MARK1,MMD,MSX2,MYCL,MYLIP,NCKAP1L,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX2-1,NKX6-1,NOS1,NOTCH3,NR2F1,NTN1,OLFM1,OLFM2,PAEP,PLEKHB1,POSTN,POU4F1,PRAME,PRDM6,PRKCZ,PSMD9,PTK2,PTPRZ1,RAB17,RAB29,RARB,RBM24,RBM38,RGMA,RND2,ROBO1,RORB,RPS6KA3,RTN4RL2,RUNX3,S100A9,S1PR3,S1PR5,SCIN,SEMA4D,SEMA7A,SGPP1,SHTN1,SLC6A4,SNAI1,SOSTDC1,SOX6,SPDEF,SPINT1,SPOCK2,SRCIN1,STK3,SULT2B1,SYAP1,SYT2,TESC,TESPA1,TLCD3B,TMEM100,TMEM176B,TMEM30A,TPH1,TRPV2,USH2A,XK,ZBTB46,ZBTB7C,ZFYVE27,ZNF703 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 1869 | 186 | ACVR2A,ACVRL1,ADAMTS20,ADAMTS3,ADCYAP1R1,ADRA1A,AFAP1L2,AKAP6,ALOX15,ALS2,ANKRD6,ANXA9,ARHGAP4,ARHGAP6,ATP6V1C2,BCL2L11,BIK,BMP2K,BMP6,BMP8A,C5,CACNB2,CALB2,CALR,CARD11,CASR,CBL,CCL26,CCN3,CD38,CD40,CD74,CD86,CDH2,CDH3,CHN2,CHP2,CHRNA7,CHRNB2,CHRNB4,CLEC16A,CLSTN3,CRLF1,CSF1R,CX3CR1,CYFIP2,CYP46A1,DCDC2,DISP1,DLL4,DOC2B,DOK5,DRD2,DRD4,DUSP9,EDA,EMP2,ENHO,EPHB2,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FOXA1,FPR2,FZD9,GAREM1,GDF6,GDF9,GHR,GLI1,GPR37,GPR37L1,GPR4,GPR65,GPRC5B,GRB2,GREM1,GRIN1,GSKIP,GUCY1A1,GUCY1A2,HAP1,HAVCR2,HTR2A,IAPP,IGSF11,IL11,IL12A,IL23R,IL7,ILDR1,INHBB,INHBC,ITM2C,JAK2,JUN,KSR1,LGMN,LGR5,LIN28A,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MSX2,MUC20,NCK2,NECTIN2,NEO1,NEURL1,NFATC4,NKD1,NKX3-1,NKX6-1,NOS1,NOS1AP,NOX4,NR2C1,NRG2,NRXN1,P2RX7,P2RY1,P2RY8,PELI1,PIK3AP1,PIK3R5,PRKCZ,PRKD2,PSMD9,PTGIS,PTK2,RAB29,RAB3B,RASGRF1,RB1CC1,RGS9,RIMS3,ROBO1,RUNDC3A,S100A9,SCEL,SCIMP,SCRIB,SCUBE1,SEMA4D,SEMA7A,SEPTIN4,SH2B3,SH2D1A,SH2D3A,SH2D3C,SH3RF2,SHKBP1,SLA2,SLC30A10,SOX4,STK3,STX1A,SULF2,SYBU,TENM1,TESPA1,TIMP3,TLR5,TLR7,TNFRSF19,TNFSF10,TNFSF15,TSPAN5,TXK,UNC5B,VAV1,VSNL1,ZDHHC13 |
| GO_NERVOUS_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1441 | 158 | ADGRB3,ADRA1A,ARL6,ASIC1,ASIC3,ATP2B2,ATP8A2,AVPR1A,AZGP1,BRINP1,CA6,CABP1,CACNA1G,CACNA1I,CACNB2,CALHM1,CAMK4,CCN3,CDC14A,CDH3,CELF4,CHRFAM7A,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CLIC5,CNGA1,CNGB1,CNIH2,COL4A3,COMP,CPEB3,CRYBB3,CRYM,CST7,CX3CR1,DCDC2,DLL4,DRD2,DRD4,EGR2,EIF4A3,EPHB2,FGFR1,FKBP1B,FZD9,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GFY,GJA3,GJC3,GLRA3,GLS,GNAT2,GPR143,GRIK5,GRIN1,GRM7,GUCA1B,GUCA1C,HOXA1,HTR2A,HTR3A,HTR3B,IAPP,IFT20,IGSF11,INSYN1,IRX5,ITGAX,JAM3,JUN,KALRN,KCND2,KCNJ11,KCNK2,KCNQ4,LGMN,LPO,MAGT1,MAPK8IP2,MBP,MYH14,MYRF,NFASC,NFATC4,NPAS1,NPY1R,NRXN1,NRXN2,NRXN3,OAT,OLFM2,OPRD1,OPRK1,OR10K1,OR1M1,OR2A7,OR2G6,OR2L5,OR51B4,OR52E2,OR5AN1,OR7D2,OR7G2,OR8G5,OTOA,P2RX7,P2RY1,PDE1B,PIGR,PJVK,POU4F1,POU4F3,PRCD,PRKAR2B,PRKCG,PRKCZ,PTAFR,PTPRZ1,RASGRF1,RDH10,RDH12,RGS9,RORB,SCN3A,SCN3B,SCN5A,SCNN1D,SEMA5B,SLC17A8,SLC1A4,SLC24A4,SLC29A1,SLC4A10,SLC52A3,SLC6A1,SLC6A4,SRRM4,STX1A,TAS2R4,TIMP3,TMEM100,TMEM150C,TMPRSS3,TNNI3,TRPA1,TRPM8,TRPV2,TUB,TUSC3,USH2A,WASF3 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1813 | 1716 | 175 | ACE,ACER2,ACER3,ACVR1C,ACVRL1,ADRA1A,AHR,AKIRIN1,ANXA9,ATP8A2,AVPR1A,AZGP1,BMP6,BTN2A2,C1QL4,CADM4,CALR,CARD11,CASR,CCL26,CCN3,CD1D,CD209,CD22,CD38,CD40,CD6,CD70,CD74,CD86,CDH2,CDH3,CDKN2A,CEACAM1,CEBPA,CEND1,CHP2,CHRD,CHRNA10,CHRNA7,CHRNB2,CLEC11A,CLEC7A,CLMN,CLU,COL4A3,COMP,CORO1A,CRLF1,CSF1R,CX3CR1,CXCR2,DEC1,DHRS2,DISP3,DLEC1,DLL4,DRD2,DUSP1,EAF2,EMP2,ETV3,FA2H,FABP6,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,FTO,FZD9,GAREM1,GDF9,GLI1,GPR37L1,GREM1,HAVCR2,HCK,HEY2,HHLA2,HLA-DPB1,HLX,HNF4A,HTR2A,IFNLR1,IFT80,IGFBP2,IL11,IL12A,IL23R,IL34,IL7,INSL4,ITGAX,JAK2,JUN,KCNK2,KDM1A,KLF5,KSR1,LGMN,LGR5,LIN28A,LRP6,LTF,MAGI2,MAP11,MAPK11,MAPK15,MAPK8IP1,MATK,MSX2,MYO16,NCCRP1,NCK2,NCKAP1L,NDRG2,NES,NEURL1,NGFR,NKX3-1,NOS2,NOTCH3,NOX4,NR5A2,NRP2,NTN1,PELI1,PLA2G2D,PLA2G4A,PLCD1,PPP1R16B,PRAME,PRKCZ,PRKD2,PTAFR,PTK2,PTPRZ1,RARB,RGN,ROBO1,RUNX3,S1PR3,SCG2,SCIN,SCN5A,SERPINB7,SGK2,SH2B3,SHC4,SLC25A27,SLC6A4,SLIT3,SOX4,SPINT1,SPN,SPTA1,SRPK2,SSTR2,ST8SIA1,STAT4,STK3,SULF2,SULT2B1,TCF7,TENM1,TES,TESC,TNFRSF8,VASH2,VIPR2,ZBTB7C,ZNF703 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 592 | 95 | ADGRB3,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,B4GALT5,BOC,CAMK2B,CDH2,CDKL3,CHODL,CHRNA7,CHRNB2,CRMP1,CSF1R,CYFIP2,DCC,DCDC2,DCLK1,DOK5,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGFR2,GFRA2,GRB2,GRIN1,IGSF9,IL1RAPL1,ISLR2,IST1,KALRN,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LINGO1,LRRC4C,LZTS1,MAP1S,MAP6,MAPK8IP2,NCAM1,NEDD4L,NEO1,NFASC,NFATC4,NGFR,NKX2-1,NKX6-1,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,OLFM1,PLPPR4,POU4F1,POU4F3,PREX2,PTK2,PTPRZ1,RAP1GAP,RND2,ROBO1,SCRIB,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SLITRK2,SLITRK3,SPTA1,SPTAN1,SPTB,SRCIN1,TMEFF2,TRPV2,UNC5B,XK,ZFYVE27 |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1428 | 155 | ACVR2A,ACVRL1,ADAMTS20,ADGRB2,ADGRB3,ADGRL1,AHI1,AKAP6,AKIRIN1,AMIGO1,ANXA9,ATOH1,ATP8A2,B4GALT5,BMP6,BOC,BRINP1,BRINP2,BTN2A2,C21orf91,C5,CACNA2D2,CACNG7,CALR,CAMK1D,CAMK2B,CBLN2,CD34,CD40,CD74,CD83,CD86,CDH15,CDH2,CDKL3,CDKN2A,CEACAM1,CEBPA,CHODL,CHRNA7,CLEC7A,CLSTN3,CNTN1,CPEB3,CSPG5,CST7,CX3CR1,CXCR2,CYBB,CYP26B1,DDHD1,DMRT1,DPYSL3,DRD2,EPHB2,EPHB3,ESRRB,FBXO31,FGF18,FGFR1,FGFR2,FGG,FKBP1B,FOXA1,FZD9,GCM1,GDF6,GHR,GLI1,GPC2,GPR37L1,GPRC5B,GREM1,HAP1,HEY2,HEYL,HLX,HTR2A,IL12A,IL1RAPL1,IL23R,IL34,IL7,ISLR2,IST1,ITGA6,ITGAX,JAK2,JUN,KALRN,KDM1A,KLF5,LIN28A,LLPH,LTF,MAGI2,MAP6,MAPK11,MARCHF5,MMD,MSX2,MYRF,NCKAP1L,NDNF,NEDD4L,NEURL1,NGFR,NKX6-1,NRXN1,NTN1,OLFM1,OLFM2,P2RX7,PLS1,POU4F1,PPP1R16B,PRKCZ,PRKD2,PTGIS,PTPRZ1,RARB,RBM24,RND2,ROBO1,RPS6KA3,RUNX3,S100A9,SCIN,SEMA4D,SEMA7A,SERPINB7,SHTN1,SLITRK2,SLITRK3,SNAI1,SOX6,SPDEF,SPINT1,STK3,SULT2B1,SYAP1,SYT2,TESC,TESPA1,TMEM100,TMEM30A,TPH1,TRPV2,VASH2,WASF3,ZBTB46,ZBTB7C,ZFYVE27,ZNF322,ZNF703 |
| GO_METAL_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 906 | 119 | ABCC8,ACTN2,ADCYAP1R1,ADRA1A,AKAP6,AMIGO1,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CAMK2B,CASR,CHRNA10,CHRNA7,CHRNB2,CLCA3P,CNTN1,CORO1A,DRD2,DRD4,FAM155A,FGF14,FKBP1B,FXYD7,GEM,GNAO1,GRIN1,HAP1,HCN2,HCN4,HTR2A,IL16,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,LILRA2,LMTK2,LTF,MAGT1,MRLN,NEDD4L,NIPAL1,NKAIN1,NMUR1,NOS1,NOS1AP,OPRD1,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,PTPN3,RGN,RGS9,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC12A8,SLC13A3,SLC17A8,SLC24A4,SLC30A10,SLC30A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC5A5,SLC9B1,SLN,TESC,TRPA1,TRPM8,TRPV2,TRPV3,TUSC3,ZDHHC13 |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 879 | 117 | ABCC8,ACTN2,AKAP6,AMIGO1,ANXA9,ASIC1,ASIC3,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CHRNA10,CHRNA7,CLCA3P,CLCN4,CNGA1,CNGB1,CNIH2,CORO1A,COX7B2,DAPK1,DRD2,DRD4,EPHB2,FAM155A,FGF14,FKBP1B,FXYD7,GEM,GRIN1,HAP1,HCN2,HCN4,HTR2A,HVCN1,IL1RAPL1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,MAGT1,MAPK8IP2,MRLN,NEDD4L,NIPAL1,NOS1,NOS1AP,NOX5,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,PTPN3,RASGRF1,RGN,RGS9,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC12A8,SLC15A1,SLC1A4,SLC24A4,SLC25A27,SLC2A12,SLC30A10,SLC30A3,SLC36A2,SLC36A3,SLC40A1,SLC4A10,SLC9B1,SLN,TESC,TRPA1,TRPM8,TRPV2,TRPV3,TUSC3,ZDHHC13 |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1935 | 185 | ABHD5,ABHD6,ACHE,ACSM2A,ACSM3,ACVR2A,ADCY4,ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,AVPR1A,AZGP1,BACE2,BCL2L11,BMP6,BMP8A,CACNA1G,CACNA2D1,CACNB2,CALB2,CALR,CARD11,CASR,CCN3,CCR6,CCRL2,CD34,CD38,CD40,CD52,CD74,CDH2,CDH3,CEBPA,CFL2,CHRNA10,CHRNA7,CNGB1,CORIN,CORO1A,CRACD,CSF1R,CX3CR1,CXCR2,CXorf21,CYB5R4,CYBB,CYP26B1,CYP39A1,CYP4F12,DISP3,DRD2,DRD4,EBF2,ESRRB,FA2H,FAM155A,FAM3B,FFAR2,FGF21,FGFR4,FKBP1B,FOXA1,FPR2,FTO,FZD9,GCNT4,GLS,GNAT2,GPR4,GPR65,GRHL1,GRIK5,GRIN1,HAP1,HCN4,HNF4A,HTR2A,HVCN1,IAPP,IL7,ILDR2,JAK2,JAM3,KCNH2,KCNJ11,KCTD17,KDM1A,KNG1,KSR2,L3MBTL3,LAMA4,LARGE2,LIN28A,LPO,LRP6,LSR,LTF,MALRD1,MAP2K6,MAPK15,MT1F,MYLIP,NCKAP1L,NEDD4L,NELL2,NEO1,NGFR,NOS1,NOS2,NOX4,NR5A2,NXN,OAS1,ORMDL3,P2RX7,P2RY1,P2RY8,PDZD8,PIGR,PLCD1,PLCH1,PLCL2,POTEE,POTEF,POTEI,PPP1R3G,PRKAR2B,PRND,PTGER4,PTPN3,PTPRN2,PYGL,RBP1,RDH12,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SCN3B,SCN5A,SGCZ,SH2B3,SLC12A8,SLC24A4,SLC25A27,SLC29A1,SLC2A4,SLC30A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC9B1,SLN,SOX4,SOX6,SPNS2,SPTA1,SYBU,SYPL2,TLE3,TMPRSS3,TNNI3,TRPA1,TRPM8,TRPV2,TUB,UGCG,USH2A,VSIG1,VSNL1,XK,XPR1 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 928 | 119 | ADGRB2,ADGRB3,ADGRL1,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,BCL11A,BMERB1,BMP6,BRINP1,BRINP2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CBLN2,CD38,CDH2,CDKL3,CEND1,CHODL,CHRNB2,CLSTN3,CNTN1,CPEB3,CRMP1,CST7,CX3CR1,DCC,DISP3,DLL4,DPYSL3,DRAXIN,DRD2,EPHB2,EPHB3,FBXO31,FGFR1,FKBP1B,FOXA1,GDF6,GLI1,GPC2,GPR37L1,GPRC5B,GRIN1,HAP1,HES2,HEY2,HEYL,IL1RAPL1,IL34,ISLR2,IST1,ITGA6,ITGAX,ITM2C,KALRN,KDM1A,KIF13B,KNDC1,LIN28A,LINGO1,LLPH,LRFN1,LRFN5,LRRC4C,LZTS1,MAGI2,MAP6,MARK1,MDGA1,MMD,MYCL,MYLIP,MYRF,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX6-1,NOS1,NOTCH3,NR2F1,NRXN1,NTN1,NTNG2,OLFM1,POU4F1,PTK2,PTPRZ1,RAB17,RAB29,RARB,RGMA,RND2,ROBO1,RTN4RL2,S100A9,S1PR5,SEMA4D,SEMA7A,SHTN1,SLC6A4,SLIT1,SLITRK2,SLITRK3,SPINT1,SRCIN1,SYT2,TMEM30A,TRPV2,WASF3,XK,ZFYVE27 |
| GO_AXON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 523 | 87 | ALS2,AMIGO1,ARHGAP4,ATOH1,ATP8A2,B4GALT5,BOC,CDH2,CDKL3,CHODL,CHRNB2,CRMP1,CSF1R,CYFIP2,DCC,DCLK1,DOK5,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,FGFR2,FKBP1B,GFRA2,GRB2,GRIN1,IGSF9,ISLR2,IST1,JAK2,JAM3,JUN,KIF13B,KIF5A,KIF5C,LHX4,LINGO1,LRRC4C,MAP1S,MAP6,NCAM1,NEO1,NFASC,NGFR,NKX2-1,NKX6-1,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,OLFM1,PLP1,PLPPR4,POU4F1,POU4F3,PTK2,PTPRZ1,RAP1GAP,RGMA,RND2,ROBO1,RTN4RL2,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SLITRK2,SLITRK3,SPTA1,SPTAN1,SPTB,TMEFF2,TRPV2,TSPAN2,UNC5B,XK,ZFYVE27 |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1813 | 1984 | 186 | ABCC1,ABHD6,ACE,ACVR1C,ACVRL1,ADD2,AKIRIN1,APC2,ARHGAP4,ASTN1,ATOH1,ATP1B1,ATP1B2,BMERB1,BOC,C5,CACNA1I,CADM4,CALR,CAMK1D,CAMK2B,CAMSAP3,CASR,CCL26,CCN3,CCR6,CCRL2,CD34,CD40,CD74,CDH1,CDH2,CDK5R2,CEACAM1,CEND1,CHRD,CHRM4,CLEC7A,CMTM2,COLEC10,CORO1A,CRMP1,CSF1R,CX3CR1,CXCR2,CYFIP2,DAPK2,DCC,DCDC2,DCLK1,DLL4,DMRT1,DNAH2,DNAH7,DNAI1,DOCK8,DOK5,DPYSL3,DPYSL5,DRAXIN,DRD2,DUSP1,EFNA2,EGR2,ELMO2,EMP2,ENAH,EPB41L5,EPHA6,EPHB2,EPHB3,ESAM,EXT1,FBXO31,FFAR2,FGF18,FGFR1,FGFR4,FLT4,FPR2,FSCN3,GCSAML,GFRA2,GPC2,GPR37,GRB2,GREM1,HCK,IGSF9,IL12A,IL16,IL33,IST1,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,JAK2,JAM3,JUN,KIF5A,KIF5C,LAMA4,LDLRAD4,LGMN,LHX4,LHX6,LRRC15,LTB4R2,MAGI2,MAP2K3,MAPK15,MARK1,MDGA1,MIA3,MPP1,MSX2,MYO1G,NCAM1,NCK2,NCKAP1L,NDNF,NEO1,NEURL1,NFASC,NKD1,NKX2-1,NKX6-1,NOX4,NRG2,NRP2,NRXN1,NRXN3,NTN1,NTN5,P2RY1,PITX2,PLAT,PODXL,POMGNT2,POSTN,POU4F1,POU4F3,PRKCZ,PRKD2,PTAFR,PTGER4,PTK2,RAP1GAP,RGN,RND2,ROBO1,S100A9,SAA4,SCG2,SCRIB,SELL,SELPLG,SEMA4D,SEMA5B,SEMA7A,SH3RF2,SHTN1,SLC9B1,SLIT1,SLIT3,SNAI1,SPN,SPNS2,SPOCK2,SPOCK3,SPTA1,SPTAN1,SPTB,SRCIN1,SRGAP3,STK26,TEKT1,TMEFF2,TNFAIP1,TUBB2A,UNC5B,VAV1,WAS,ZNF703 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 748 | 104 | ADGRB3,ALS2,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,B4GALT5,BOC,CALR,CAMK2B,CDH2,CDKL3,CHODL,CHRNA7,CHRNB2,CRMP1,CSF1R,CSPG5,CYFIP2,DCC,DCDC2,DCLK1,DOK5,DPYSL5,DRAXIN,DRD2,EFNA2,EGR2,ENAH,EPB41L5,EPHA6,EPHB2,EPHB3,EXT1,FBXO31,FGFR2,FGG,GFRA2,GRB2,GRIN1,IGSF9,IL1RAPL1,ISLR2,IST1,ITGB7,KALRN,KIF13B,KIF5A,KIF5C,KNDC1,LHX4,LINGO1,LRRC4C,LZTS1,MAP1S,MAP6,MAPK8IP2,NCAM1,NEDD4L,NEO1,NFASC,NFATC4,NGFR,NKX2-1,NKX6-1,NRP2,NRXN1,NRXN3,NTN1,NTN5,NTNG2,OLFM1,PLPPR4,POSTN,POU4F1,POU4F3,PREX2,PTK2,PTPRZ1,RADIL,RAP1GAP,RND2,ROBO1,SCRIB,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SLITRK2,SLITRK3,SPTA1,SPTAN1,SPTB,SRCIN1,TMEFF2,TRPV2,UNC5B,VSIG1,VWA2,XK,ZFYVE27 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 1863 | 177 | ADCYAP1R1,ADRA1A,AKAP6,ALOX15,ALS2,ANKRD6,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ARHGEF3,BCL2L11,BMP6,BMP8A,BTN2A2,BTRC,C1QL4,C5,CADM4,CALR,CARD11,CASR,CBL,CCL26,CCN3,CD22,CD40,CD74,CD86,CDH2,CEACAM1,CHN2,CHP2,CHRNA10,CHRNA7,CLEC16A,CLU,CSF1R,CX3CR1,CYTH4,DAPK2,DEPDC5,DOK5,DRD2,DRD4,DUSP1,DUSP26,DUSP9,EDA,EPHB2,FGD2,FGD5,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FKBP1B,FLT4,FPR2,GAREM1,GDF6,GDF9,GHR,GPR143,GPR37,GPR37L1,GPR4,GPR65,GPRC5B,GRB2,GREM1,GUCY1A1,GUCY1A2,HAP1,HAVCR2,HTR2A,IAPP,IL11,INHBB,INHBC,JAK2,JUN,KALRN,KDM1A,KLHL31,KSR1,LIN28A,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MCF2L,MCF2L2,MUC20,NCK2,NDRG2,NKX3-1,NOS1,NOS1AP,NOX4,NPFFR2,NRG2,OTUD3,P2RX7,P2RY1,P2RY8,PDE10A,PDE11A,PELI1,PEX5L,PIK3AP1,PIK3R5,PIP4K2A,PIP5K1B,PLEKHG1,PLEKHG4B,POU4F1,PPP1R16B,PREX2,PRKCZ,PRKD2,PSD,PSD2,PTK2,RALGAPB,RALGPS1,RAP1GAP,RASGRF1,RB1CC1,RGN,RHOV,RNF125,ROBO1,RUNDC3A,S100A9,SCIMP,SEMA4D,SEMA7A,SEPTIN4,SGSM3,SH2B3,SH3RF2,SLA2,SLC30A10,SNAI1,SRGAP3,STARD8,STK3,TAF13,TAF1L,TENM1,THEM4,TIMP3,TLR7,TMEM100,TNFAIP1,TNFRSF19,TNFSF10,TNFSF15,TRIP10,UNC5B,VAV1,VRK3,ZDHHC13 |
| GO_REGULATION_OF_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 699 | 98 | ABCB1,ACTN2,ADCYAP1R1,AKAP6,AMIGO1,ANO9,ANXA9,ATP1B1,ATP1B2,ATP8A2,AVPR1A,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CAMK2B,CASR,CHRNB2,CLCA3P,CLDN10,CLIC5,CNIH2,CNTN1,CORO1A,CYBB,DAPK1,DRD2,DRD4,EPHB2,FGF14,FGFR1,FKBP1B,FXYD7,GEM,GNAO1,GRIN1,GRM7,HAP1,HCN2,HCN4,HTR2A,HTR3A,HVCN1,IL16,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNMB1,KCNN2,KCNQ4,KCNV1,LILRA2,MAP2K6,MAPK8IP2,MRLN,NEDD4L,NKAIN1,NOS1,NOS1AP,NOX5,OPRD1,P2RX7,P2RY1,PTAFR,PTPN3,RAB3B,RASGRF1,RGN,RGS9,SCN3A,SCN3B,SCN4B,SCN5A,SLC30A10,SLC6A1,SLC6A4,SLN,SYT13,SYT2,SYT5,TESC,TRPV2,TRPV3 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 1429 | 148 | ABHD5,ACE,ACER2,ACVR1C,ADCY4,ADCYAP1R1,ADGRB3,ADRA1A,AFAP1L2,AGAP2,AGAP4,ALS2,APC2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ARRDC4,ATP1B1,ATP1B2,AVPR1A,AZIN2,BCL2L11,C5,CASP14,CASR,CCL26,CD40,CD74,CDH3,CDK5R2,CHN2,CHP2,CHRNA7,CLEC7A,CLU,COL4A3,CSF1R,CYFIP2,DAPK1,DEPDC5,DNAJC1,DOCK8,DOK7,DRD2,DRD4,DUSP9,DYNLL1,EMP2,EVI5,FGD2,FGF18,FGFR1,FGFR2,FGFR3,FGFR4,FPR2,GHR,GNAO1,GPR65,GPRC5B,GREM1,GRIN1,GRTP1,GUCA1B,GUCA1C,HIGD1A,HTR2A,IL23R,ITGA6,ITGAM,ITK,JAK2,JUN,KALRN,KSR1,LGMN,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK15,MAPRE3,MBP,MMD,MMP16,MUC20,NCKAP1L,NEURL1,NGFR,NKX3-1,NMUR1,NOS1,NOS1AP,NOS2,NOX4,P2RX7,PIK3R5,PLIN5,PPM1J,PPP1R3G,PREX2,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTK2,RALGAPB,RAP1GAP,RASGRF1,RGN,RGPD3,RGS10,RGS7,RGS9,ROBO1,S100A9,SCRIB,SEMA4D,SGSM1,SGSM3,SRCIN1,SRGAP3,STARD8,STK26,STK3,SYAP1,TBC1D1,TBC1D29P,TBC1D30,TENM1,TIGAR,TNFSF10,TNFSF15,TNNT2,TOR1AIP2,TXK,USP6NL,VAV1,VRK3 |
| GO_CHEMICAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 1207 | 133 | ABHD5,ACSM2A,ACSM3,ADCY4,ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,AVPR1A,BACE2,BMP6,CACNA1G,CACNA2D1,CACNB2,CALB2,CALR,CASR,CCR6,CCRL2,CD38,CD40,CD52,CEBPA,CHRNA10,CHRNA7,CNGB1,CORIN,CORO1A,CX3CR1,CXCR2,CXorf21,CYB5R4,CYP26B1,CYP39A1,CYP4F12,DISP3,DRD2,DRD4,FA2H,FAM155A,FAM3B,FFAR2,FGF21,FGFR4,FKBP1B,FOXA1,FPR2,FZD9,GLS,GNAT2,GPR4,GPR65,GRHL1,GRIK5,GRIN1,HAP1,HCN4,HNF4A,HTR2A,IAPP,JAK2,KCNH2,KCNJ11,KCTD17,KNG1,LIN28A,LRP6,LSR,LTF,MALRD1,MT1F,MYLIP,NEDD4L,NEO1,NGFR,NOS1,NOX4,NR5A2,OAS1,ORMDL3,P2RX7,P2RY1,P2RY8,PDZD8,PLCD1,PLCH1,PLCL2,PPP1R3G,PRKAR2B,PRND,PTGER4,PTPN3,PTPRN2,PYGL,RBP1,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SCN3B,SCN5A,SLC12A8,SLC24A4,SLC25A27,SLC29A1,SLC2A4,SLC30A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC9B1,SOX4,SYBU,SYPL2,TMPRSS3,TNNI3,TRPA1,TRPM8,UGCG,VSNL1,XK,XPR1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1724 | 162 | ACE,ACER2,ACVR1C,ACVR2A,ACVRL1,ADCY4,ADRA1A,AFAP1L2,ALOX15,ALS2,ANKRD6,ANXA9,APC2,ARRDC4,BCL2L11,BMP6,BMP8A,BTRC,C5,CARD11,CASP14,CASR,CCL26,CD40,CD74,CD86,CDH2,CDK5R2,CDK9,CEBPA,CHRNA7,CLEC7A,CLU,CNEP1R1,CNTN1,COL4A3,CPEB3,CRLF1,CSF1R,CX3CR1,CYBB,CYFIP2,DAPK1,DOK5,DOK7,DRD2,DRD4,DUSP26,DUSP9,EIF4A3,EMP2,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GHR,GPR37,GPR37L1,GPRC5B,GREM1,GRIN1,HAVCR2,HIGD1A,HTR2A,HUWE1,IAPP,IL11,IL12A,IL23R,IL33,IL34,INHBB,INHBC,IST1,JAK2,JUN,KDM1A,KLKB1,KNDC1,KPNA7,KSR1,LGMN,LIN28A,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MAPRE3,MBP,MMD,MUC20,MYLIP,NCK2,NCKAP1L,NEDD4L,NEURL1,NGFR,NKD1,NKX3-1,NOS1,NOS1AP,NOX4,OAZ2,OPRD1,P2RX7,P2RY1,PELI1,PIK3R5,PPP1R16B,PRDM6,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTK2,RB1CC1,RGN,RMND1,ROBO1,S100A9,SCIMP,SEC22B,SEMA4D,SEMA7A,SEPTIN4,SGSM3,SH2D3A,SH2D3C,SH3RF2,SLC30A10,SOCS4,SOX4,SPN,SPSB4,SRCIN1,STK26,STK3,SYAP1,SYMPK,TENM1,TLR7,TNFRSF19,TNFRSF8,TNFSF10,TNFSF15,UBE2D1,VRK3 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1823 | 167 | ACE,ACVR2A,ACVRL1,ADCY4,ADCYAP1R1,ADRA1A,AFAP1L2,AGAP2,ALOX15,ALS2,ANKRD6,ANXA9,BMP6,BMP8A,BTN2A2,C1QL4,C5,CADM4,CAMSAP3,CASR,CBL,CCL26,CD40,CD74,CDH2,CDK5R2,CDK9,CDKN2A,CEACAM1,CEBPA,CHP2,CHRNA10,CHRNA7,CLU,CNEP1R1,CNTD2,CNTN1,CRLF1,CSF1R,CX3CR1,DIRAS3,DOK5,DOK7,DRD2,DRD4,DUSP1,DUSP26,DUSP9,DYNLL1,ELFN1,EMP2,EPHB2,ESRRB,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FKBP1B,FLT4,FPR2,GAREM1,GDF6,GDF9,GFRA2,GHR,GPATCH2,GPR37,GPR37L1,GPRC5B,GRB2,GREM1,GSKIP,GUCA1B,GUCA1C,HAVCR2,HERC5,HIGD1A,HTR2A,IAPP,IL11,IL12A,IL23R,IL34,IL7,INHBB,INHBC,ITGA6,JAK2,JUN,KIRREL2,KLHL31,KNDC1,KSR1,LDLRAD4,LMTK2,LMTK3,LRP6,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MAPRE3,MMD,MUC20,NCK2,NCKAP1L,NDRG2,NEURL1,NKX3-1,NOS1,NOS2,NOX4,NPFFR2,OPRD1,P2RX7,P2RY1,PIK3R5,PLCL2,PPP1R14C,PPP1R16B,PPP1R1C,PPP1R42,PPP2R2C,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTK2,RB1CC1,RGN,RIMBP2,ROBO1,SCIMP,SEMA4D,SEMA7A,SFI1,SH2B3,SH2D3A,SH2D3C,SH3RF2,SLA2,SLC30A10,SOCS4,SRCIN1,STK26,STK3,SYAP1,SYMPK,TENM1,TESC,TIGAR,TIMP3,TLR7,TNFRSF19,TNFSF15,VRK3,ZGPAT |
| GO_REGULATION_OF_MEMBRANE_POTENTIAL | 0.0e+00 | 0.0e+00 | 1813 | 435 | 73 | ACTN2,ADRA1A,AKAP6,ASIC1,ATP1A3,ATP1B1,ATP1B2,CACNA1G,CACNA1I,CACNA2D1,CACNB2,CELF4,CHRFAM7A,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CNIH2,DRD2,DRD4,DSC2,EIF4A3,FGF14,FKBP1B,FZD9,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GLRA3,GRID1,GRIK4,GRIK5,GRIN1,HCN2,HCN4,HTR3A,HTR3B,IGSF11,INSYN1,JUN,KCNC1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNJ11,KCNJ5,KCNK2,KCNK5,KCNK9,KCNN2,MAPK8IP2,MYH14,NEDD4L,NOS1AP,NRXN1,OPRD1,P2RX7,PRKCZ,PTPN3,RIMS3,SCN3A,SCN3B,SCN4B,SCN5A,SLC1A6,SLC25A27,SLC29A1,STX1A |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 1000 | 115 | ACVR2A,ACVRL1,ADAMTS20,AHI1,AKAP6,AKIRIN1,AMIGO1,ANXA9,ATOH1,ATP8A2,BMP6,BOC,BRINP1,BRINP2,BTN2A2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CD34,CD74,CD83,CD86,CDH15,CDH2,CDKL3,CEACAM1,CEBPA,CHODL,CLEC7A,CNTN1,CPEB3,CSPG5,CX3CR1,CYP26B1,DPYSL3,DRD2,EPHB2,FBXO31,FGF18,FGFR1,FGG,FKBP1B,FOXA1,GDF6,GPC2,GPRC5B,GREM1,HAP1,HEYL,HLX,HTR2A,IL12A,IL1RAPL1,IL23R,IL34,IL7,ISLR2,IST1,ITGA6,JAK2,JUN,KALRN,KDM1A,KLF5,LIN28A,LLPH,LTF,MAGI2,MAP6,MAPK11,MMD,MSX2,NCKAP1L,NDNF,NEDD4L,NEURL1,NGFR,NKX6-1,NTN1,OLFM1,OLFM2,POU4F1,PRKCZ,PTPRZ1,RARB,RBM24,RND2,ROBO1,RPS6KA3,RUNX3,S100A9,SCIN,SEMA4D,SEMA7A,SHTN1,SNAI1,SOX6,SPDEF,SPINT1,STK3,SULT2B1,SYAP1,SYT2,TESC,TESPA1,TMEM100,TMEM30A,TPH1,TRPV2,ZBTB46,ZBTB7C,ZFYVE27,ZNF703 |
| GO_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 659 | 90 | ADGRB3,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,BCL11A,BMP6,BRINP1,BRINP2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CD38,CDH2,CDKL3,CHODL,CHRNB2,CNTN1,CPEB3,CRMP1,DCC,DISP3,DPYSL3,DRAXIN,EPHB2,EPHB3,FBXO31,FGFR1,FKBP1B,FOXA1,GDF6,GPC2,GPR37L1,GPRC5B,GRIN1,HEY2,HEYL,IL1RAPL1,ISLR2,IST1,ITGA6,ITM2C,KALRN,KDM1A,KIF13B,KNDC1,LIN28A,LINGO1,LLPH,LRRC4C,LZTS1,MAGI2,MAP6,MARK1,MMD,MYCL,MYLIP,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX6-1,NOTCH3,NR2F1,NTN1,OLFM1,PTK2,RAB17,RAB29,RARB,RGMA,RND2,ROBO1,RTN4RL2,S100A9,S1PR5,SEMA4D,SEMA7A,SHTN1,SLC6A4,SRCIN1,SYT2,TMEM30A,TRPV2,XK,ZFYVE27 |
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1405 | 140 | ABHD5,ABHD6,ABO,ACER2,ACER3,ACHE,ACSL6,ACSM2A,ACSM3,ADH1B,AGAP2,AGMO,AGPS,AKR1B15,AKR1D1,ALAS1,ALDH3B2,ALOX15,AVPR1A,B4GALT4,B4GALT5,BMP6,BMX,CD74,CEACAM1,CEBPA,CES3,CLU,CNEP1R1,CPT1A,CPT1C,CSF1R,CYB5R1,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2B6,CYP2J2,CYP2S1,CYP39A1,CYP46A1,CYP4F12,CYP4F3,CYP4F8,DDHD1,DHH,DHRS2,DHRS9,DISP3,EFR3B,ELOVL4,ENHO,ENPP6,ESYT3,ETFBKMT,ETNPPL,FA2H,FABP6,FADS6,FAM126B,FGF21,FGFR1,FGFR3,FGFR4,FPR2,GDPD1,GPAT4,GPC2,GRHL1,HNF4A,HSD11B2,HSD17B6,HTR2A,LGMN,LIPH,LIPI,LPCAT2,LSR,MALRD1,NKX2-1,NR5A2,ORMDL3,OSBPL6,P2RX7,PCYT1B,PHOSPHO1,PI4KAP2,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,PLCD1,PLCH1,PLCL2,PLCXD3,PLIN5,PLP1,PLPP2,PLPP4,PLPPR4,PPM1L,PRKAR2B,PRKD2,PTGIS,PTGR1,PTK2,PTPRN2,RBP1,RDH10,RDH12,RGN,SBF1,SERAC1,SFTPB,SGPP1,SIRT4,SLA2,SLC27A6,SLC44A3,SMPDL3B,SNAI1,SOCS4,SPNS2,SRD5A2,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,SULT2B1,SULT4A1,TFCP2L1,THEM4,TLCD3B,UGCG,UGT8 |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 1287 | 132 | A2ML1,ABHD5,ACER2,ACVR1C,ADCYAP1R1,ADGRB3,ADRA1A,AGAP2,AGAP4,ALS2,APC2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ATP1B1,ATP1B2,AVPR1A,BCL2L11,C5,CAMSAP3,CASP14,CASR,CCL26,CD40,CHN2,CHP2,CLEC7A,CNN3,COL4A3,CST7,CYFIP2,DAPK1,DEPDC5,DNAJC1,DOCK8,DRD2,DYNLL1,ELFN1,EPHB3,EVI5,FGD2,FGD5,FGFR1,FGFR2,FGFR3,FKBP1B,GNAO1,GPATCH2,GPR65,GRIN1,GRTP1,HTR2A,ITGA6,ITIH5,ITK,JAK2,JUN,KALRN,KNG1,LAMP3,LGMN,LMTK2,LMTK3,LTF,MAGI2,MBP,NCKAP1L,NGFR,NKX3-1,NMUR1,NOS1,OAS1,OASL,PCSK5,PLIN5,PPP1R14C,PPP1R16B,PPP1R1C,PPP1R42,PPP2R2C,PREX2,PRKCZ,PRKD2,PTAFR,PTK2,PTPRN2,RALGAPB,RAP1GAP,RASGRF1,RGN,RGPD3,RGS10,RGS7,RGS9,RIMBP2,ROBO1,RPS6KA3,S100A9,SBF1,SCRIB,SEMA4D,SERPINB7,SERPINB9,SFI1,SGSM1,SGSM3,SH3RF2,SPINK13,SPINT1,SPOCK2,SPOCK3,SRGAP3,STARD8,TBC1D1,TBC1D29P,TBC1D30,TIMP3,TIMP4,TNFSF10,TNFSF15,TNNI3,TNNT2,TOR1AIP2,TXK,USP6NL,VAV1,VRK3 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1670 | 155 | ACE,ACVR2A,AHR,AKIRIN1,ALOX15,AZGP1,BTN2A2,BTNL9,BTRC,C5,CALR,CAMK1D,CAMK4,CARD11,CCN3,CCR6,CD1D,CD209,CD22,CD300C,CD34,CD38,CD3D,CD40,CD6,CD70,CD74,CD83,CD86,CEACAM1,CEBPA,CFHR1,CHRNB2,CLEC7A,CLU,COLEC10,CORO1A,CR2,CRTAM,CST7,CX3CR1,CXCR2,CYFIP2,CYP26B1,DAPK2,DOCK8,DRD2,DUSP1,ELMO2,FCN1,FFAR2,FGG,FGL1,FPR2,FYB2,GBP5,GCSAML,GPRC5B,GRB2,GREM1,HAVCR2,HCK,HERC5,HHLA2,HLA-DPB1,HLX,ICAM2,IFNLR1,IGFBP2,IL12A,IL23R,IL33,IL34,IL7,ITGAL,ITGAM,ITGB7,ITK,JAK2,JAM3,JUN,KLK7,KLRC1,LAIR1,LGMN,LILRA2,LRFN5,LTF,MAP2K6,MAPK10,MAPK8IP1,MIA3,MPP1,MUC20,MYO10,MYO1G,NCK2,NCKAP1L,NECTIN2,P2RX7,PAX5,PELI1,PIANP,PIGR,PIK3AP1,PLA2G2D,PLCL2,PLPP4,POU4F1,PRKCZ,PRKD2,PSMD9,PTAFR,PTGER4,PTK2,RAB29,RAET1G,RNF125,RNF216,RPS6KA3,RUNX3,S100A9,SAMHD1,SCIMP,SCIN,SCRIB,SELL,SEMA7A,SERPINB9,SFTPA2,SH2D1A,SLA2,SLAMF7,SMPDL3B,SPN,SPNS2,SPTA1,SUSD4,TAFA3,TESC,TESPA1,THEMIS2,TLR10,TLR5,TLR7,TMEM176B,TRAC,TRAFD1,TXK,UBE2D1,ULBP1,ULBP3,VAV1,WAS,ZBTB46 |
| GO_CIRCULATORY_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 554 | 81 | ACE,ACSM3,ACVRL1,ADRA1A,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,AVPR1A,BMP6,CACNA1G,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CASR,CD34,CD38,CEACAM1,CELF2,COL4A3,COMP,CORIN,CXCR2,CYP2J2,CYP4F12,DLL4,DRD2,DSC2,EMP2,F5,FGG,FKBP1B,FXYD7,GNAO1,GPR37L1,GUCY1A1,GUCY1B1,HCN4,HEY2,HSD11B2,HTR2A,IRX5,JAK2,KCND1,KCND2,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNJ12,KCNJ5,KCNMB1,KCNN2,KLK1,KNG1,MAP2K3,MAP2K6,MYL2,NCALD,NEDD4L,NOS1,NOS1AP,NOS2,NOX4,NPY1R,P2RY1,PCSK5,POSTN,PTAFR,RYR1,RYR3,SCN3B,SCN4B,SCN5A,SGCZ,SLC4A5,SLC6A4,TNNI3,TNNT2 |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1146 | 122 | ACE,ACVR2A,ACVRL1,ADCY4,ADCYAP1R1,ADRA1A,AFAP1L2,AGAP2,ALOX15,ALS2,ANKRD6,ANXA9,BMP6,BMP8A,C5,CASR,CCL26,CD40,CD74,CDH2,CDK5R2,CDK9,CHP2,CHRNA7,CLU,CNEP1R1,CNTN1,CRLF1,CSF1R,CX3CR1,DOK5,DOK7,DRD2,DRD4,DUSP26,DUSP9,EMP2,ESRRB,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GHR,GPR37,GPR37L1,GPRC5B,GREM1,GUCA1B,GUCA1C,HAVCR2,HIGD1A,HTR2A,IAPP,IL11,IL12A,IL23R,IL34,INHBB,INHBC,ITGA6,JAK2,JUN,KNDC1,KSR1,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MAPRE3,MMD,MUC20,NCKAP1L,NEURL1,NKX3-1,NOS1,NOS2,NOX4,OPRD1,P2RX7,P2RY1,PIK3R5,PPP1R16B,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTK2,RB1CC1,RGN,ROBO1,SCIMP,SEMA4D,SEMA7A,SH2D3A,SH2D3C,SH3RF2,SLC30A10,SRCIN1,STK26,STK3,SYAP1,SYMPK,TENM1,TIGAR,TNFRSF19,TNFSF15,VRK3 |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 1071 | 117 | ACVRL1,AHI1,ALX4,ANKRD6,ANXA9,ARL6,ATOH1,ATP8A2,ATRNL1,BARX2,BCL2L11,BMP6,BTRC,CD34,CDH2,CEACAM1,CHRNA10,COMP,CRB1,CSF1R,CSGALNACT1,CYP26B1,DLL4,EDA,EIF4A3,EOMES,EPHB2,ETV7,FGF18,FGFR1,FGFR2,FGFR3,FGL1,FOXA1,FRAS1,GCNT3,GCNT4,GLI1,GNAO1,GNAT2,GREB1L,GREM1,HESX1,HEY2,HEYL,HLX,HOXA1,HOXB13,IFT80,IL7,IRX5,ITGA6,ITGAX,JUN,KCNQ4,KIF26B,LHX4,LRP6,LTF,MAGI2,MESP2,MMP13,MMP16,MSX2,MYL2,NKD1,NKX2-1,NKX3-1,NKX6-1,NPY1R,NR5A2,NRP2,NTN1,NTN5,NTNG2,OLFM1,P2RX7,PAX5,PAX9,PHOSPHO1,PITX2,POU4F1,POU4F3,PSMD9,PTK2,RARB,RDH10,ROBO1,RORB,RYR1,SCN5A,SCRIB,SDK2,SFTPB,SLC24A4,SLC40A1,SLC4A10,SLC6A4,SLIT1,SLIT3,SNAI1,SOSTDC1,SOX4,SP5,SP6,SULF2,TCF7,TDRD7,TLE3,TMEFF2,TMEM100,TMEM176B,TNNI3,TNNT2,TSPAN12,USH2A,VWA2 |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 984 | 111 | ABCB1,ACHE,ACTN2,ADCYAP1R1,AHI1,AKAP6,AMIGO1,ANXA9,ATP1B1,ATP1B2,ATP8A2,AVPR1A,AZIN2,BMP6,C5,CACNA1G,CACNA1I,CACNA2D1,CACNB2,CALR,CAMK1D,CASR,CBL,CD34,CD38,CDH1,CDH2,CDH3,CDK5R2,CHP2,CHRNB2,CLEC7A,CLU,CNTN1,CRTAM,CSF1R,DMAP1,DOC2B,DRD2,DRD4,EPHB2,FCN1,FFAR2,FGF14,FGF21,FGFR1,FGG,FPR2,GREM1,GRIN1,HAP1,HAVCR2,HTR3A,HUWE1,IL2RB,IL33,ILDR1,INHBB,ITGAM,JAK2,KCNC1,KCNE5,KCNH2,KCNJ11,KCNMB1,LILRA2,MAGI2,MAP2K6,MAPK11,MAPK8IP1,MAPK8IP2,MBP,NCKAP1L,NEDD4L,NKX3-1,NKX6-1,NOS1,NOS1AP,OAZ2,P2RX7,P2RY1,PAEP,POSTN,PRKCZ,PSMD9,PTAFR,PTGER4,RAB29,RAB3B,RGN,RGS9,SCAMP5,SCIN,SCN3B,SCN4B,SCN5A,SCYL2,SGK2,SLC30A3,SLC6A1,SLC6A4,SOX4,STX1A,SYBU,TENM1,TESC,TMEM30A,TRPV2,TRPV3,TUB,VSNL1 |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 955 | 109 | ADGRB3,AKAP6,AMIGO1,ARHGAP4,ARHGAP44,ATOH1,ATP8A2,BCL11A,BMERB1,BMP6,BRINP1,BRINP2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CD38,CDH2,CDKL3,CHODL,CHRNB2,CLEC7A,CNTN1,CPEB3,CRMP1,CSPG5,CX3CR1,DCC,DISP3,DLL4,DPYSL3,DRAXIN,DRD2,EPHB2,EPHB3,FBXO31,FGFR1,FGG,FKBP1B,FOXA1,GDF6,GPC2,GPR37L1,GPRC5B,GRIN1,HAP1,HES2,HEY2,HEYL,IL1RAPL1,IL34,ISLR2,IST1,ITGA6,ITM2C,KALRN,KDM1A,KIF13B,KNDC1,LIN28A,LINGO1,LLPH,LRRC4C,LTF,LZTS1,MAGI2,MAP6,MARK1,MMD,MYCL,MYLIP,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX6-1,NOS1,NOTCH3,NR2F1,NTN1,OLFM1,PAEP,POSTN,POU4F1,PTK2,PTPRZ1,RAB17,RAB29,RARB,RGMA,RND2,ROBO1,RTN4RL2,S100A9,S1PR3,S1PR5,SEMA4D,SEMA7A,SHTN1,SLC6A4,SPINT1,SRCIN1,SYT2,TMEM30A,TRPV2,XK,ZFYVE27 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1813 | 1698 | 155 | ABCC1,ACER2,ACTN2,ACVR1C,ADCY4,ADCYAP1R1,AHR,AICDA,AKAP6,AMIGO1,AOC1,ATP1A3,ATP6V0B,ATP6V1C2,AVPR1A,BCL11A,BCL2L11,BMP6,BRINP1,BRINP2,CACNA2D1,CALR,CASR,CBL,CD38,CD40,CD6,CD86,CDH1,CEACAM1,CHRM4,CHRNA7,CHRNB2,CLEC7A,CLU,COL4A3,CPEB3,CPT1A,CX3CR1,CYBB,CYP1A1,CYP1A2,CYP26B1,DAPK1,DHH,DMAP1,DRD2,DRD4,DUSP1,EGR2,ENHO,FFAR2,FGF21,FGFR2,FKBP1B,FOXA1,FPR2,GHR,GLDC,GLRA3,GNAL,GNAO1,GPR37,GPR37L1,GRB2,GRIK5,GRIN1,GUCY1B1,HAVCR2,HBA1,HCK,HCN2,HCN4,HNF4A,HOXB13,HP,HSD11B2,HTR2A,HTR3A,HTR3B,IGFBP2,IL12A,IL23R,ILDR2,INHBB,JAK2,JUN,KCNJ11,KCNMB1,KDM1A,KLF5,LGMN,LILRA2,LIN28A,LRP6,LTF,MAFA,MAP2K6,MAP4K1,MAPK10,MMP13,MRC1,MSX2,MT1F,NEURL1,NFATC4,NGFR,NKX3-1,NKX6-1,NOS1,NOS2,NOX4,NUGGC,P2RX7,P2RY1,PALM3,PELI1,POSTN,POU4F1,PRKAR2B,PRKCZ,PTAFR,PTGER4,PTK2,PTPRN2,RARB,RDH12,RGN,RGS10,RGS9,RORB,RPS6KA3,RYR3,SCIMP,SELL,SLC29A1,SLC2A4,SLC30A10,SLC5A5,SLC6A1,SLC6A4,SLIT3,SOX4,SSTR2,STAT4,STK26,SYAP1,SYBU,TESC,TIMP4,TNFSF10,TRPA1,VSNL1,VWA2,ZNF703 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1880 | 165 | ACE,ACER2,ACVR2A,ACVRL1,ADCY4,ADRA1A,AFAP1L2,ALOX15,ALS2,ANKRD6,ANXA9,ARRDC4,BMP6,BMP8A,BTN2A2,C1QL4,C5,CADM4,CASR,CBL,CCL26,CD40,CD74,CDH2,CDK5R2,CDK9,CDKN2A,CDYL,CEACAM1,CEBPA,CHRNA10,CHRNA7,CLU,CNEP1R1,CNTD2,CNTN1,CRLF1,CSF1R,CX3CR1,DIRAS3,DOK5,DOK7,DRD2,DRD4,DUSP1,DUSP26,DUSP9,ELFN1,EMP2,EPHB2,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FKBP1B,FLT4,FPR2,GAREM1,GDF6,GDF9,GFRA2,GHR,GPR37,GPR37L1,GPRC5B,GRB2,GREM1,GSKIP,HAVCR2,HERC5,HIGD1A,HTR2A,HUWE1,IAPP,IL11,IL12A,IL23R,IL34,IL7,INHBB,INHBC,JAK2,JUN,KDM1A,KIRREL2,KLHL31,KNDC1,KPNA7,KSR1,LDLRAD4,LMTK2,LRP6,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MAPRE3,MMD,MUC20,NCK2,NCKAP1L,NDRG2,NEURL1,NKX3-1,NOS1,NOS1AP,NOX4,NPFFR2,NXN,OPRD1,P2RX7,P2RY1,PAX5,PELI1,PIK3R5,PLCL2,PPP1R14C,PPP1R16B,PPP1R1C,PPP2R2C,PRDM6,PRKAR2B,PRKCG,PRKCZ,PRKD2,PTK2,RB1CC1,RGN,ROBO1,SCIMP,SEMA4D,SEMA7A,SEPTIN4,SH2B3,SH2D3A,SH2D3C,SH3RF2,SLC30A10,SOCS4,SOX4,SPSB4,SRCIN1,STK26,STK3,SYAP1,SYMPK,TENM1,TESC,TIMP3,TLR7,TNFRSF19,TNFSF15,UBE2D1,VRK3,ZGPAT |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1962 | 169 | ABCC1,ABHD5,ACER2,ACER3,ACSL6,ACSM2A,ACSM3,ADA2,ADCY4,ADCYAP1R1,ADH1B,ADHFE1,AGMO,AGPS,AICDA,AK5,AK7,AK9,AKR1B15,AKR1D1,ALDH3B2,ALOX15,ASMTL,ASRGL1,AVPR1A,AZIN2,B3GNT3,B4GALT4,B4GALT5,BMP6,CA6,CARD11,CD74,CEACAM1,CEBPA,CHST4,CHST6,CPT1A,CPT1C,CRYM,CRYZL1,CSGALNACT1,CSPG5,CTRC,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2B6,CYP2J2,CYP2S1,CYP39A1,CYP46A1,CYP4F12,CYP4F22,CYP4F3,CYP4F8,DDC,DHRS9,DISP3,ELOVL4,ENTPD3,ESRRB,ETFBKMT,EXTL2,FA2H,FADS6,FGFR1,FGFR4,FMOD,GAD1,GALM,GDPD1,GGTLC3,GHR,GLDC,GLS,GLS2,GPAT4,GUCA1B,GUCA1C,GUCY1A1,GUCY1A2,GUCY1B1,HAL,HNF4A,HTR2A,HYAL4,HYKK,ITIH5,KCNJ11,KDM1A,LCMT1,LGMN,LPO,LRGUK,MALRD1,MAT1A,MDH1,ME3,MFN1,MIOX,MPP1,MTAP,NDNF,NOS1,NOS2,NOX4,NOXRED1,NPY1R,NR5A2,OAS1,OAT,OAZ2,OGDHL,OSBPL6,OXCT2,P2RX7,P2RY1,PADI4,PANK3,PDE10A,PDE4C,PLA2G4A,PLCD1,PLCH1,PLCL2,PLIN5,PLP1,PPIP5K1,PPP1R3G,PRELP,PRKAR2B,PRTFDC1,PSMD9,PTAFR,PTGIS,PTGR1,RBP1,RDH10,RDH12,RGN,RIMKLA,RIMKLB,SAMHD1,SDS,SGPP1,SIRT4,SLC22A11,SLC27A6,SLC52A3,SNAI1,SPOCK2,SPOCK3,SRD5A2,ST3GAL2,SULT2B1,SULT4A1,TARS3,TAT,TBPL1,THEM4,TIGAR,TPH1,TPH2,TPST1,VCAN,VNN2,XYLT1 |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 1765 | 157 | ABCC1,ACER3,AFAP1L2,AICDA,ALOX15,ALS2,ASIC1,BACE2,BMP6,BRINP1,BTRC,C5,CAMK1D,CAMK2B,CAMK4,CARD11,CCL26,CCN3,CCR6,CCRL2,CD1D,CD209,CD300C,CD40,CD6,CD74,CD83,CEACAM1,CEBPA,CHST4,CIITA,CLEC1A,CLEC7A,CLU,COLEC10,CORO1A,CR2,CREB3L3,CRTAM,CSF1R,CST7,CX3CR1,CXCR2,CYBB,CYP26B1,DAPK1,DCDC2,DRD2,DRD4,FCN1,FFAR2,FGG,FPR2,GBP5,GNLY,GPRC5B,HAVCR2,HCK,HERC5,HLA-DPB1,HP,HTN3,ICAM2,IFNLR1,IL12A,IL1R2,IL23R,IL33,IL34,INHBB,ITGAL,ITGAM,ITK,JAK2,JAM3,JUN,KLK7,KLKB1,KLRC3,KNG1,LGMN,LILRA2,LILRB5,LPO,LRFN5,LTB4R2,LTF,LY9,MAP2K3,MAP2K6,MAPK8IP2,MRC1,MUC20,NCAM1,NECTIN2,NFATC4,NFRKB,NOS2,NOX4,NOX5,OAS1,OASL,OPRK1,P2RX7,PADI4,PELI1,PIK3AP1,PLA2G2D,PLP1,POLR3A,PPP6C,PRKCZ,PSMD9,PSTPIP1,PTAFR,PTGER4,PTGIS,RAET1G,RNF125,RNF216,RPS6KA3,S100A9,S1PR3,SAA4,SAMHD1,SCG2,SCIMP,SCRIB,SCUBE1,SEMA7A,SERPINB9,SFTPA2,SH2D1A,SIGLEC11,SIGLEC14,SLAMF7,SMPDL3B,SPN,SRPK2,STAB1,STAT4,SUSD4,TAFA3,THEMIS2,TLR10,TLR5,TLR7,TPST1,TRAFD1,TSPAN2,TXK,UBE2D1,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_REGULATION_OF_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 824 | 98 | ABCC8,ACHE,ACVR1C,ADRA1A,ASIC1,AVPR1A,BMP6,BMP8A,BTN2A2,C5,CACNA1G,CACNA1I,CACNA2D2,CACNB2,CASR,CCN3,CD22,CD34,CD38,CD40,CD74,CDK5R2,CEACAM1,CHRNB2,CHRNB4,CORIN,CPLX1,CPT1A,CRTAM,CSF1R,CSPG5,DISP1,DNAJC1,DOC2B,DRD2,DRD4,ENHO,FCN1,FFAR2,FGFR1,FGG,FKBP1B,GDF9,GRIK5,GRM7,HAP1,HAVCR2,HNF4A,HTR2A,IL11,IL1R2,IL1RAPL1,IL33,ILDR1,INHBB,ITGAM,JAK2,KALRN,KCNJ11,LGI3,LILRA2,MAP2K6,MAPK11,MBP,MCTP2,NKX3-1,NKX6-1,NOS2,OPRK1,P2RX7,P2RY1,PAEP,POSTN,PRKCG,PRKCZ,PSMD9,PTAFR,PTGER4,RAB3B,RIMS3,SCAMP5,SCIN,SEPTIN4,SIRT4,SLC6A1,SLC6A4,SOX4,SRCIN1,STX1A,SYBU,SYP,SYT13,SYT2,SYT5,TLR10,TLR5,TRIM9,VSNL1 |
| GO_REGULATION_OF_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 614 | 82 | ACE,ADRA1A,AKAP6,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,AVPR1A,BMP6,CACNA1G,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CAMK2B,CASR,CCN3,CD38,CDK9,CELF2,CELF4,CHRNA7,CHRNB4,CNIH2,CORIN,CST7,CYP2J2,DRD2,DSC2,EIF4A3,EMP2,FGFR1,FGG,FKBP1B,FTO,FXYD7,GDF9,GLS,GNAO1,GRIN1,GUCY1A1,HCN4,HEY2,HTR2A,IGSF11,INHBB,IRX5,ITGAX,JAK2,KCND1,KCND2,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNJ12,KCNJ5,KCNN2,MYL2,MYRF,NKX3-1,NOS1,NOS1AP,NRXN1,OPRD1,OPRK1,PRKCZ,PTAFR,PTK2,RYR1,RYR3,SCN3B,SCN4B,SCN5A,SLN,SSTR2,STX1A,TMEM100,TNNI3,TNNT2,WASF3 |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 687 | 87 | ADGRB3,AKIRIN1,AMIGO1,ARHGAP4,ARHGAP44,ATP8A2,BCL11A,C21orf91,CACNG7,CAMK1D,CAMK2B,CD38,CDH2,CDKL3,CHODL,CHRNB2,CNTN1,CPEB3,CRMP1,DCC,DCDC2,DPYSL3,DRAXIN,EPHB2,EPHB3,FBXO31,FGFR1,FKBP1B,GPC2,GRIN1,HAP1,IFT20,IL1RAPL1,ISLR2,IST1,ITGA6,ITM2C,KALRN,KCTD17,KDM1A,KIF13B,KLF5,KNDC1,LINGO1,LLPH,LRRC4C,LZTS1,MAGI2,MAP6,MAPK15,MARK1,MYLIP,MYO10,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX6-1,NR2F1,NTN1,OLFM1,P2RX7,PLS1,PODXL,PPP1R16B,PTK2,RAB17,RAB29,RAP1GAP,RGMA,RND2,ROBO1,RTN4RL2,S100A9,SEMA4D,SEMA7A,SHTN1,SRCIN1,SYT2,TBC1D30,TENM1,TMEM30A,TRPV2,WAS,XK,ZFYVE27 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 995 | 108 | ADAM22,ADAM23,ADGRL2,AHI1,AMIGO1,ARL6,ATOH1,AVPR1A,B4GALT5,BACE2,BCL2L11,BMERB1,C21orf91,CDH1,CDH2,CDK5R2,CEND1,CHRD,CHRNB2,CLU,CNTN1,CSF1R,CX3CR1,CXCR2,DCC,DCLK1,DLL4,DRAXIN,DRD2,DYNLL1,EFNA2,EGR2,EML1,EOMES,EPHB2,EPHB3,EXT1,FA2H,FGFR1,FGFR2,FPR2,GCM1,GLI1,GNAO1,GPR37L1,GRIN1,HAP1,HESX1,HPCAL4,HYDIN,IL34,ITGAM,JHY,KCNC1,KDM1A,KIF27,KNDC1,LHX4,LHX6,LRP6,MAP1S,MAST1,MBP,MDGA1,METTL14,MNX1,MYO16,MYRF,NDRG2,NES,NEURL1,NKX2-1,NKX6-1,NOTCH3,NPAS1,NRP2,PAX5,PITX2,PLP1,PLXDC1,POTEE,POU4F1,PTK2,PTPRZ1,RARB,ROBO1,RPS6KA3,RTN4RL2,SCN5A,SCRIB,SEMA7A,SLC17A8,SLC4A10,SLC6A11,SLC6A4,SLIT1,SMARCA1,SOX4,SOX6,SSTR2,STK3,SYPL2,TACC1,TIMP4,TSPAN2,UGT8,VCAN,WASF3 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 1721 | 152 | ABCC1,ACTN2,ACVR1C,ACVR2A,ACVRL1,ADCY4,ADCYAP1R1,ADRA1A,AHR,AKAP6,AMIGO1,AOC1,ATP1A3,ATP6V0B,ATP6V1C2,AVPR1A,BCL11A,BCL2L11,BMP6,CACNA2D1,CALR,CASR,CBL,CD38,CDH1,CEACAM1,CGN,CHRD,CHRM4,CHRNA7,CHRNB2,COMP,CORO1A,CPEB3,CX3CR1,CYBB,CYP1A2,DDC,DHH,DLL4,DRD2,DRD4,DUSP1,EGR2,EIF4A3,ENHO,EPB41L5,ESRRB,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FMOD,FOXA1,FPR2,GABRA1,GABRB2,GAREM1,GDF6,GDF9,GHR,GNAL,GNAO1,GRB2,GREM1,GREM2,HCN2,HCN4,HEYL,HNF4A,HOXB13,HSD11B2,HTR2A,HTR3A,HTR3B,IGFBP2,INHBB,JAK2,JUN,KCNC1,KCNJ11,KDM1A,KLF5,LDLRAD4,LGMN,LGR5,LRP6,MAGI2,MIA3,MSX2,NEO1,NEURL1,NGFR,NKX2-1,NKX3-1,NKX6-1,NOS1,NOS2,NOX4,NPFFR1,NPFFR2,NR2C1,NR2F1,NR5A2,NR6A1,P2RX7,P2RY1,POSTN,POU4F1,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTGER4,PTK2,RARB,RGMA,RGS10,RGS9,RORB,RUNX3,RYR1,RYR3,SHISA2,SLC2A4,SLC30A10,SLC5A5,SLC6A1,SLC6A4,SLIT3,SOSTDC1,SOX6,SPINT1,SSTR2,STAT4,SULF2,SYAP1,TAT,TDGF1P3,TIGAR,TIMP3,TIMP4,TMEM100,TNFSF10,TPH2,TUB,UBE2D1,UGCG,VWA2,ZNF703 |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1813 | 1625 | 146 | ACE,ACVR2A,ACVRL1,ADCY4,ADRA1A,AFAP1L2,AGAP2,ALOX15,ALS2,ANKRD6,ANXA9,BMP6,BMP8A,BTN2A2,C1QL4,C5,CADM4,CASR,CBL,CCL26,CD40,CD74,CDH2,CDK5R2,CDK9,CDKN2A,CEACAM1,CEBPA,CHRNA10,CHRNA7,CLU,CNTD2,CNTN1,CRLF1,CSF1R,CX3CR1,DIRAS3,DOK5,DOK7,DRD2,DRD4,DUSP1,DUSP26,DUSP9,DYNLL1,EMP2,EPHB2,ESRRB,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GFRA2,GHR,GPR37,GPR37L1,GPRC5B,GRB2,GREM1,GSKIP,HAVCR2,HERC5,HIGD1A,HTR2A,IAPP,IL11,IL12A,IL23R,IL34,IL7,INHBB,INHBC,ITGA6,JAK2,JUN,KIRREL2,KLHL31,KNDC1,KSR1,LDLRAD4,LRP6,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MAPRE3,MMD,MUC20,NCK2,NCKAP1L,NDRG2,NEURL1,NKX3-1,NOS1,NOX4,NPFFR2,OPRD1,P2RX7,P2RY1,PIK3R5,PLCL2,PPP1R14C,PRKAR2B,PRKCZ,PRKD2,PTK2,RB1CC1,RGN,ROBO1,SCIMP,SEMA4D,SEMA7A,SH2B3,SH2D3A,SH2D3C,SH3RF2,SLA2,SLC30A10,SOCS4,SRCIN1,STK26,STK3,SYAP1,TENM1,TESC,TIGAR,TIMP3,TLR7,TNFRSF19,TNFSF15,VRK3,ZGPAT |
| GO_TAXIS | 0.0e+00 | 0.0e+00 | 1813 | 652 | 84 | ABCC1,AKIRIN1,ATOH1,BOC,C5,CALR,CAMK1D,CASR,CCL26,CCN3,CCR6,CCRL2,CD74,CMTM2,COLEC10,CORO1A,CRMP1,CSF1R,CX3CR1,CXCR2,CYFIP2,DAPK2,DCC,DOK5,DPYSL5,DRAXIN,DUSP1,EFNA2,EGR2,ELMO2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,FFAR2,FGF18,FGFR1,FPR2,GFRA2,GRB2,GREM1,IGSF9,IL12A,IL16,JAM3,KIF5A,KIF5C,LGMN,LHX4,LTB4R2,MPP1,NCAM1,NCKAP1L,NEO1,NFASC,NKX2-1,NRP2,NRXN1,NRXN3,NTN1,NTN5,POU4F3,PRKD2,PTAFR,PTK2,RAP1GAP,ROBO1,S100A9,SAA4,SCG2,SCRIB,SEMA4D,SEMA5B,SEMA7A,SLIT1,SLIT3,SPN,SPTA1,SPTAN1,SPTB,TMEFF2,UNC5B,VAV1 |
| GO_MONOVALENT_INORGANIC_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 537 | 75 | ABCC8,ACTN2,AKAP6,AMIGO1,ASIC1,ASIC3,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP6V0B,ATP6V1C2,CACNA1G,CACNA1I,CLCN4,CNTN1,COX7B2,DRD2,DRD4,FXYD7,HCN2,HCN4,HTR2A,HVCN1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,NEDD4L,NKAIN1,NOS1,NOS1AP,NOX5,P2RX7,PTPN3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC12A8,SLC13A3,SLC15A1,SLC17A8,SLC24A4,SLC25A27,SLC2A12,SLC36A2,SLC36A3,SLC4A10,SLC4A5,SLC4A8,SLC5A5,SLC9B1,TESC |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 1427 | 133 | ABHD6,ACHE,ACVR1C,ADRA1A,AMER2,ANKRD6,APC2,ARHGAP44,ASIC1,AVPR1A,BICC1,BMP8A,BTN2A2,BTRC,C1QL4,CADM4,CALR,CBL,CCN3,CD22,CD38,CD74,CDH2,CEACAM1,CELF4,CHRD,CHRNA10,CLU,CX3CR1,CYP26B1,DACT3,DCC,DDIT4L,DEPDC5,DLL4,DRAXIN,DRD2,DUSP1,DUSP26,DUSP9,EIF4A3,ENHO,EPHB2,FGG,FKBP1B,FZD9,GLI1,GPR37L1,GRB2,GREM1,GREM2,HEY2,HEYL,HIGD1A,HTR2A,IFT80,IGFBP2,IGSF1,IL11,IL1R2,IL7,INHBB,ITGA6,KALRN,KCNJ11,KDM1A,KLHL31,LDLRAD4,LGMN,LILRA2,LRP6,LTF,MAGI2,MAPK8IP1,MAPK8IP2,NCK2,NDRG2,NEURL1,NFATC4,NKD1,NKX2-1,NKX3-1,NOTCH3,NTN1,NXN,OTUD3,P2RX7,PALM3,PDE10A,PDE11A,PLCL2,PLIN5,PRAME,PRKCZ,PSMD9,PTPN3,RB1CC1,RGS10,RGS7,RGS9,RITA1,RNF125,RNF43,ROBO1,SAMHD1,SCG2,SCRIB,SCYL2,SH2B3,SH3RF2,SHISA2,SIRT4,SLA2,SLC6A1,SLC6A4,SLIT3,SMPDL3B,SNAI1,SOCS4,SOSTDC1,STAM2,STK3,SULF2,THEM4,TIMP3,TLE3,TNFAIP1,TNFSF10,TSPAN15,UNC5B,VRK3,VSNL1,ZGPAT |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1247 | 122 | ACE,ACVR2A,ACVRL1,ADCY4,ADRA1A,AFAP1L2,ALOX15,ALS2,ANKRD6,ANXA9,ARRDC4,BMP6,BMP8A,C5,CASR,CCL26,CD40,CD74,CDH2,CDK5R2,CDK9,CHRNA7,CLU,CNEP1R1,CNTN1,CRLF1,CSF1R,CX3CR1,DOK5,DOK7,DRD2,DRD4,DUSP26,DUSP9,EMP2,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GHR,GPR37,GPR37L1,GPRC5B,GREM1,HAVCR2,HIGD1A,HTR2A,HUWE1,IAPP,IL11,IL12A,IL23R,IL34,INHBB,INHBC,JAK2,JUN,KDM1A,KNDC1,KPNA7,KSR1,LTF,MAGI2,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MAPRE3,MMD,MUC20,NCKAP1L,NEURL1,NKX3-1,NOS1,NOS1AP,NOX4,OPRD1,P2RX7,P2RY1,PELI1,PIK3R5,PPP1R16B,PRDM6,PRKAR2B,PRKCZ,PRKD2,PTK2,RB1CC1,ROBO1,SCIMP,SEMA4D,SEMA7A,SEPTIN4,SH2D3A,SH2D3C,SH3RF2,SLC30A10,SOX4,SPSB4,SRCIN1,STK26,STK3,SYAP1,SYMPK,TENM1,TNFRSF19,TNFSF15,UBE2D1,VRK3 |
| GO_CELLULAR_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 963 | 104 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,AVPR1A,BMP6,CACNA2D1,CACNB2,CALB2,CALR,CASR,CCR6,CCRL2,CD38,CD40,CD52,CFL2,CHRNA10,CHRNA7,CNGB1,CORO1A,CX3CR1,CXCR2,CXorf21,CYBB,DRD2,DRD4,FAM155A,FGF21,FKBP1B,FPR2,FZD9,GNAT2,GPR4,GPR65,GRIK5,GRIN1,HAP1,HTR2A,HVCN1,IAPP,JAK2,KCNJ11,KCTD17,KNG1,LARGE2,LIN28A,LPO,LRP6,LTF,MT1F,NEDD4L,NELL2,NGFR,NOS1,NOS2,NOX4,NXN,ORMDL3,P2RX7,P2RY1,P2RY8,PDZD8,PLCD1,PLCH1,PLCL2,PRND,PTGER4,PTPRN2,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SGCZ,SLC12A8,SLC24A4,SLC25A27,SLC29A1,SLC30A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC9B1,SOX4,SYBU,SYPL2,TMPRSS3,TNNI3,TRPA1,TRPM8,VSNL1,XK,XPR1 |
| GO_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 831 | 95 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,AVPR1A,BMP6,CACNA1G,CACNA2D1,CACNB2,CALB2,CALR,CASR,CCR6,CCRL2,CD38,CD40,CD52,CHRNA10,CHRNA7,CNGB1,CORIN,CORO1A,CX3CR1,CXCR2,CXorf21,CYP4F12,DRD2,DRD4,FAM155A,FGFR4,FKBP1B,FPR2,FZD9,GLS,GNAT2,GPR4,GPR65,GRIN1,HAP1,HCN4,HNF4A,HTR2A,IAPP,JAK2,KCNH2,KCTD17,KNG1,LRP6,LTF,MT1F,NEDD4L,NEO1,NOS1,P2RX7,P2RY1,P2RY8,PDZD8,PLCD1,PLCH1,PLCL2,PRND,PTGER4,PTPN3,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SCN3B,SCN5A,SLC12A8,SLC24A4,SLC25A27,SLC30A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC9B1,SYPL2,TMPRSS3,TNNI3,TRPA1,TRPM8,XK,XPR1 |
| GO_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 486 | 70 | ABCB1,ACTN2,AKAP6,AMIGO1,ANO9,ATP1B1,ATP1B2,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CLCA3P,CLIC5,CNIH2,CORO1A,CYBB,DAPK1,DRD2,DRD4,EPHB2,FGF14,FKBP1B,FXYD7,GEM,GRIN1,HAP1,HCN2,HCN4,HTR3A,HVCN1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNMB1,KCNN2,KCNQ4,KCNV1,MAPK8IP2,MRLN,NEDD4L,NOS1,NOS1AP,NOX5,P2RX7,PTAFR,PTPN3,RASGRF1,RGN,RGS9,SCN3A,SCN3B,SCN4B,SCN5A,SLN,TESC |
| GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 504 | 71 | ADGRB3,AMIGO1,ARHGAP4,ARHGAP44,ATP8A2,BCL11A,C21orf91,CACNG7,CAMK1D,CAMK2B,CD38,CDH2,CDKL3,CHODL,CHRNB2,CNTN1,CPEB3,CRMP1,DCC,DPYSL3,DRAXIN,EPHB2,EPHB3,FBXO31,FGFR1,FKBP1B,GPC2,GRIN1,IL1RAPL1,ISLR2,IST1,ITGA6,ITM2C,KALRN,KDM1A,KIF13B,KNDC1,LINGO1,LLPH,LRRC4C,LZTS1,MAGI2,MAP6,MARK1,MYLIP,NDNF,NEDD4L,NEURL1,NFATC4,NGFR,NKX6-1,NR2F1,NTN1,OLFM1,PTK2,RAB17,RAB29,RGMA,RND2,ROBO1,RTN4RL2,S100A9,SEMA4D,SEMA7A,SHTN1,SRCIN1,SYT2,TMEM30A,TRPV2,XK,ZFYVE27 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1813 | 1748 | 150 | ACER2,ACER3,ACTN2,ACVR1C,ADAMTS20,ADCYAP1R1,AGAP2,AHI1,ALX4,ARHGEF3,ATOH1,ATOX1,BCL2L11,BIK,BMP6,BMP8A,CALR,CAMK1D,CARD11,CASP14,CBL,CCN3,CD34,CD38,CD40,CD74,CDKN2A,CHRNA7,CLEC7A,CLU,COL4A3,COMP,CORO1A,CRLF1,CSF1R,CX3CR1,CXCR2,DAPK1,DAPK2,DCC,DHRS2,DOCK8,DRAXIN,DRD2,DUSP1,FGD2,FGF21,FGFR1,FGFR2,FGG,FLT4,FOXA1,FZD9,GABRB2,GDF6,GDF9,GLS2,GPR37,GPR37L1,GREM1,GRIK5,GRIN1,HBA1,HCK,HEY2,HIGD1A,HP,IAPP,IL12A,IL2RB,IL7,INHBB,INHBC,ITGA6,ITGAM,ITM2C,JAK2,JUN,KALRN,KCNK2,KDM1A,KNG1,LAMP3,LCMT1,LGMN,LHX4,LRP6,LTF,MAP2K6,MAPK8IP1,MAPK8IP2,MCF2L,MSX2,MT1F,NCK2,NCKAP1L,NDNF,NES,NEURL1,NFATC4,NGFR,NKX3-1,NOA1,NOX4,NUGGC,OLFM1,P2RX7,PELI1,PNMA2,POU4F1,PRAME,PRKCG,PRKCZ,PTGIS,PTK2,PTPRZ1,RAB29,RARB,RB1CC1,RGN,ROBO1,RPS6KA3,S100A9,SCG2,SCIMP,SCIN,SCRIB,SEMA4D,SEPTIN4,SERPINB9,SH3RF2,SIRT4,SLC25A27,SLC30A10,SLC40A1,SNAI1,SOX4,SPDEF,SRPK2,STK26,STK3,TCF7,TEX11,TIGAR,TIMP3,TNFRSF8,TNFSF10,TNFSF15,UNC5B,VAV1 |
| GO_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 444 | 66 | ABHD6,ACHE,ADRA1A,ASIC1,CACNA2D2,CACNB2,CALB2,CAMK2B,CD38,CDH1,CDH2,CELF4,CHRNA7,CHRNB2,CHRNB4,CLSTN3,CNIH2,CPEB3,CPLX1,CSPG5,CX3CR1,CYP46A1,DCC,DRD2,DRD4,EGR2,EIF4A3,EPHB2,FGF14,GRID1,GRIK4,GRIK5,GRIN1,GRM7,GUCY1A1,GUCY1B1,HAP1,HTR2A,IGSF11,JAK2,LGMN,LRRC4C,LZTS1,MAPK8IP2,MCTP2,NEURL1,NFATC4,NRXN1,NTNG2,P2RY1,PLAT,PLCL2,PRKAR2B,PRKCG,PRKCZ,RAB3B,RASGRF1,RIMS3,RNF216,SLC4A10,SLC6A1,SLC6A4,STX1A,SYBU,SYN3,SYP |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1813 | 974 | 103 | ACTN2,ADRA1A,ALOX15,ANKRD6,BMP6,BMP8A,BTN2A2,BTRC,C1QL4,C5,CASR,CCL26,CD40,CD74,CDH2,CEACAM1,CHRNA10,CHRNA7,CSF1R,DOK5,DRD2,DRD4,DUSP1,DUSP26,DUSP9,EPHB2,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GFRA2,GHR,GPR37,GPR37L1,GRB2,GRIN1,HAVCR2,HTR2A,IAPP,IL11,IL17RD,IL2RB,IL3RA,INHBB,INHBC,JAK2,JUN,KLHL31,KSR1,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK15,MAPK8IP1,MAPK8IP2,MBP,MUC20,NCAM1,NDRG2,NOX4,NPFFR2,NRG2,P2RX7,P2RY1,PIK3R5,PPM1L,PRKCZ,PRKD2,PSMD9,PTGER4,PTK2,RASGRF1,RB1CC1,ROBO1,SCG2,SCIMP,SEMA7A,SH2B3,SH2D3A,SH2D3C,SH3RF2,SLC30A10,SPTA1,SPTAN1,SPTB,STK26,STK3,TENM1,TIMP3,TNFRSF19,VRK3 |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 767 | 89 | ABHD5,ACER2,ACVR1C,ADCYAP1R1,ADGRB3,ADRA1A,AGAP2,AGAP4,ALS2,APC2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ATP1B1,ATP1B2,AVPR1A,BCL2L11,CASP14,CASR,CCL26,CD40,CHN2,CHP2,CLEC7A,COL4A3,CYFIP2,DAPK1,DEPDC5,DNAJC1,DOCK8,DYNLL1,EVI5,FGFR1,FGFR2,FGFR3,GNAO1,GPR65,GRIN1,GRTP1,HTR2A,ITGA6,ITK,JAK2,JUN,KALRN,LGMN,MAGI2,MBP,NCKAP1L,NGFR,NKX3-1,NMUR1,PLIN5,PREX2,PRKCZ,PRKD2,PTAFR,RALGAPB,RAP1GAP,RASGRF1,RGN,RGPD3,RGS10,RGS7,RGS9,ROBO1,S100A9,SCRIB,SEMA4D,SGSM1,SGSM3,SRGAP3,STARD8,TBC1D1,TBC1D29P,TBC1D30,TNFSF10,TNFSF15,TNNT2,TOR1AIP2,TXK,USP6NL,VAV1,VRK3 |
| GO_SYNAPSE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 414 | 63 | ACHE,ADD2,ADGRB2,ADGRB3,ADGRL1,ALS2,AMIGO1,ARHGAP44,CACNA2D2,CACNB2,CAMK2B,CAMKV,CBLN2,CDH1,CDH2,CHRNA7,CHRNB2,CLSTN3,CRIPT,CX3CR1,DLGAP3,DRD2,ELFN1,EPHB2,EPHB3,FZD9,GABRA1,GABRB2,GRIN1,IGSF9,IL1RAPL1,ITGAM,KALRN,LGMN,LRFN1,LRFN5,LRRC4C,MAGI2,MDGA1,MESD,NEURL1,NFASC,NFATC4,NOS1AP,NRP2,NRXN1,NRXN2,NTN1,NTNG2,POU4F1,PTK2,RAB17,RAB29,SDK2,SEMA4D,SLIT1,SLITRK2,SLITRK3,SPOCK2,SRCIN1,SYBU,TMEFF2,WASF3 |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 1813 | 1758 | 149 | ABCC1,ABHD6,ACE,ACVR1C,ACVRL1,ADD2,AKIRIN1,APC2,ARHGAP4,ASTN1,ATOH1,ATP1B1,ATP1B2,BMERB1,C5,CACNA1I,CADM4,CALR,CAMK1D,CAMK2B,CAMSAP3,CCL26,CCN3,CCR6,CCRL2,CD34,CD40,CD74,CDH1,CDH2,CDK5R2,CEACAM1,CEND1,CHRD,CLEC7A,CORO1A,CSF1R,CX3CR1,CXCR2,DAPK2,DCC,DCDC2,DCLK1,DLL4,DMRT1,DNAH2,DNAH7,DNAI1,DOCK8,DPYSL3,DRD2,DUSP1,ELMO2,EMP2,ENAH,EPB41L5,EPHB3,ESAM,FBXO31,FFAR2,FGF18,FGFR1,FGFR4,FLT4,FPR2,FSCN3,GCSAML,GPC2,GRB2,GREM1,HCK,IL12A,IL16,IL33,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,JAK2,JAM3,JUN,LAMA4,LDLRAD4,LGMN,LHX6,LRRC15,LTB4R2,MAGI2,MAP2K3,MAPK15,MARK1,MDGA1,MIA3,MPP1,MSX2,MYO1G,NCK2,NCKAP1L,NDNF,NEURL1,NKD1,NKX2-1,NKX6-1,NOX4,NRG2,NRP2,NTN1,P2RY1,PITX2,PLAT,PODXL,POMGNT2,POSTN,POU4F1,PRKCZ,PRKD2,PTAFR,PTGER4,PTK2,RGN,RND2,ROBO1,S100A9,SAA4,SCG2,SCRIB,SELL,SELPLG,SEMA4D,SEMA7A,SH3RF2,SHTN1,SLC9B1,SNAI1,SPN,SPNS2,SPOCK2,SPOCK3,SRCIN1,SRGAP3,STK26,TEKT1,TMEFF2,TNFAIP1,TUBB2A,VAV1,WAS,ZNF703 |
| GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 573 | 75 | ABCB1,ACTN2,AKAP6,AMIGO1,ANO9,ATP1B1,ATP1B2,AZIN2,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CLCA3P,CLIC5,CNIH2,CORO1A,CTTNBP2NL,CYBB,DAPK1,DRD2,DRD4,EPHB2,FGF14,FGF21,FKBP1B,FXYD7,GEM,GRIN1,HAP1,HCN2,HCN4,HTR3A,HVCN1,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNMB1,KCNN2,KCNQ4,KCNV1,MAPK8IP2,MRLN,NEDD4L,NOS1,NOS1AP,NOX5,OAZ2,P2RX7,PTAFR,PTPN3,RASGRF1,RGN,RGS9,SCN3A,SCN3B,SCN4B,SCN5A,SLC25A27,SLN,TESC |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 547 | 73 | ADGRB2,ADGRB3,ADGRL1,AMIGO1,ATOH1,ATP8A2,BMP6,BRINP1,BRINP2,C21orf91,CACNG7,CAMK1D,CAMK2B,CBLN2,CDKL3,CHODL,CLSTN3,CNTN1,CPEB3,CST7,CX3CR1,DPYSL3,DRD2,EPHB2,EPHB3,FBXO31,FGFR1,FKBP1B,FOXA1,GDF6,GLI1,GPC2,GPR37L1,GPRC5B,HAP1,HEYL,IL1RAPL1,IL34,ISLR2,IST1,ITGA6,ITGAX,KALRN,KDM1A,LIN28A,LLPH,MAGI2,MAP6,MMD,MYRF,NDNF,NEDD4L,NEURL1,NGFR,NKX6-1,NRXN1,NTN1,PTPRZ1,RARB,RND2,ROBO1,S100A9,SEMA4D,SEMA7A,SHTN1,SLITRK2,SLITRK3,SPINT1,SYT2,TMEM30A,TRPV2,WASF3,ZFYVE27 |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1813 | 1051 | 107 | ACVR1C,ACVR2A,ACVRL1,ADAMTS3,AFAP1L2,AHI1,ATP6V0B,ATP6V1C2,BMP6,BMP8A,BTBD11,CADM4,CBL,CCN3,CDH3,CEACAM1,CGN,CHRD,CNKSR1,COL4A3,COMP,CSF1R,CYBB,CYFIP2,DMRT1,DOK5,EFNA2,ELMO2,ENHO,EPHA6,EPHB2,EPHB3,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,FMOD,GAREM1,GDF6,GDF9,GFRA2,GHR,GRB2,GREM1,GREM2,GRIN1,GUCA1B,HAP1,HCK,HNF4A,IFT20,IGFBP2,IGSF1,INHBB,INHBC,JAK2,JUN,KALRN,LDLRAD4,LGMN,LMTK2,MAGI2,MAPK11,MATK,MSX2,MUC20,NCK2,NCKAP1L,NEO1,NEURL1,NFATC4,NGFR,NKX2-1,NKX3-1,NRG2,NRP2,PDGFRL,PIGR,PLAT,PPM1L,PRKCZ,PRKD2,PTK2,PTPN3,REPS2,RGMA,ROBO1,SH2B3,SH3TC2,SHISA2,SHKBP1,SLC30A10,SOCS4,SOSTDC1,STAM2,SULF2,TDGF1P3,TMEM100,UBE2D1,VAV1,VWA2,ZFYVE27,ZGPAT,ZNF703 |
| GO_SIGNAL_RELEASE | 0.0e+00 | 0.0e+00 | 1813 | 458 | 66 | ABCC8,ACVR1C,ADRA1A,ASIC1,BMP6,BMP8A,CACNA2D2,CACNB2,CASR,CCN3,CD38,CHRNB2,CHRNB4,CPLX1,CPT1A,CSPG5,CYB5R4,DOC2B,DRD2,ENHO,FAM3B,FFAR2,FGFR1,FGG,FKBP1B,GAD1,GDF9,GRIK5,HNF4A,HTR2A,IL11,ILDR1,ILDR2,INHBB,JAK2,KALRN,KCNJ11,MAFA,MCTP2,NKX3-1,NKX6-1,NOS2,NRXN1,NRXN2,P2RX7,P2RY1,PRKCG,PSMD9,PTPRN2,RIMS3,RPH3A,SCRIB,SIRT4,SLC16A10,SLC16A2,SLC18A2,SOX4,STX11,STX1A,SYBU,SYN3,SYP,SYT2,SYT5,TRIM9,VSNL1 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1187 | 115 | ACVR2A,AKIRIN1,AZGP1,BTN2A2,BTNL9,BTRC,C5,CALR,CAMK1D,CARD11,CCR6,CD1D,CD209,CD22,CD38,CD3D,CD40,CD6,CD70,CD74,CD83,CD86,CEACAM1,CEBPA,CFHR1,CHRNB2,CLEC7A,CLU,COLEC10,CORO1A,CR2,CRTAM,CX3CR1,CXCR2,CYFIP2,DAPK2,DOCK8,ELMO2,FCN1,FFAR2,FGG,FPR2,FYB2,GBP5,GCSAML,GPRC5B,GRB2,HAVCR2,HCK,HHLA2,HLA-DPB1,HLX,ICAM2,IGFBP2,IL12A,IL23R,IL33,IL34,IL7,ITGAM,ITK,JUN,KLK7,LGMN,LILRA2,LTF,MAP2K6,MIA3,MUC20,MYO10,MYO1G,NCK2,NCKAP1L,NECTIN2,P2RX7,PAX5,PELI1,PIK3AP1,PLCL2,PLPP4,POU4F1,PRKCZ,PRKD2,PSMD9,PTAFR,PTK2,RAB29,RAET1G,RNF125,RPS6KA3,RUNX3,S100A9,SCIMP,SCIN,SEMA7A,SFTPA2,SH2D1A,SLA2,SMPDL3B,SPN,SPTA1,SUSD4,TAFA3,TESC,TESPA1,THEMIS2,TLR10,TLR5,TLR7,TRAC,TXK,UBE2D1,VAV1,WAS,ZBTB46 |
| GO_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1813 | 1457 | 131 | ACE,ACVR1C,ACVR2A,ADAM28,ADCYAP1R1,AVPR1A,AZIN2,BCL2L11,BIK,BMP6,BRINP1,CACNA1I,CALR,CBL,CCR6,CD38,CDYL,CEBPA,CELF4,CLIC5,CORIN,CYP1A1,CYP26B1,DDX25,DHH,DMRT1,DNAI1,DPY19L2,DPY19L2P1,DPY19L2P2,DUSP1,EAF2,EMP2,EOMES,FAM9A,FAM9B,FGFR2,FOXA1,FSCN3,GCM1,GDF9,GLI1,GRB2,GREB1L,GRIN1,HAVCR2,HEY2,HNF4A,HOOK1,HOXB13,HS6ST1,HSD11B2,HVCN1,IFT20,IGFBP2,INHBB,IRX5,IZUMO1,JAM3,KALRN,LGR5,LHX4,LIN28A,LRGUK,LRP6,MAP2K6,MAPK15,MAPK8IP2,MC2R,METTL14,MSX2,NECTIN2,NEURL1,NKX2-1,NKX3-1,NOX5,NPAS1,NR6A1,NUP210L,P2RY1,PAEP,PARP11,PAX5,PCDH12,PCSK5,PCYT1B,PIWIL3,PLAC1,PLCD1,PRND,PTAFR,PTCHD3,PTGIS,PTK2,RAD21L1,RDH10,RGN,SBF1,SEPTIN4,SEPTIN6,SLC6A4,SLC9B1,SLIT3,SNAI1,SPANXA1,SPATA32,SPEF2,SPINK13,SPINT1,SRD5A2,SSTR2,STK3,STRBP,SYCE2,TAF1L,TBPL1,TCF7,TDRD7,TDRKH,TDRP,TESK2,TEX11,TEX12,TFCP2L1,TIMP4,TNFSF10,TRO,TSNAX,TSSK1B,VASH2,VMP1 |
| GO_CELLULAR_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 683 | 82 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,ATP6V0B,ATP6V1C2,AVPR1A,BMP6,CACNA2D1,CACNB2,CALB2,CALR,CASR,CCR6,CCRL2,CD38,CD40,CD52,CHRNA10,CHRNA7,CNGB1,CORO1A,CX3CR1,CXCR2,CXorf21,DRD2,DRD4,FAM155A,FKBP1B,FPR2,FZD9,GNAT2,GPR4,GPR65,GRIN1,HAP1,HTR2A,IAPP,JAK2,KCTD17,KNG1,LRP6,LTF,MT1F,NEDD4L,NOS1,P2RX7,P2RY1,P2RY8,PDZD8,PLCD1,PLCH1,PLCL2,PRND,PTGER4,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SLC24A4,SLC25A27,SLC30A3,SLC40A1,SLC4A10,SLC4A5,SLC4A8,SLC9B1,SYPL2,TMPRSS3,TNNI3,TRPA1,TRPM8,XK,XPR1 |
| GO_REGULATION_OF_HORMONE_LEVELS | 0.0e+00 | 0.0e+00 | 1813 | 524 | 70 | ABCC8,ACE,ACHE,ACVR1C,ADH1B,AKR1B15,AKR1D1,BACE2,BMP6,BMP8A,CACNA2D2,CASR,CCN3,CD38,CORIN,CPLX1,CPT1A,CRYM,CYB5R4,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2S1,CYP46A1,DHRS2,DHRS9,DOC2B,DRD2,ENHO,FAM3B,FFAR2,FGFR1,FGG,FKBP1B,FOXA1,GCNT4,GDF9,GHR,HNF4A,HSD11B2,HSD17B6,IL11,ILDR1,ILDR2,INHBB,JAK2,KALRN,KCNJ11,MAFA,NKX3-1,NKX6-1,NOS2,P2RY1,PCSK2,PCSK5,PSMD9,PTPRN2,RBP1,RDH10,RDH12,SIRT4,SLC16A10,SLC16A2,SLC5A5,SOX4,SRD5A2,STX1A,SYBU,VSNL1 |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1064 | 106 | ABHD5,ABHD6,ABO,ACER2,ACER3,ACHE,ACSL6,ACSM2A,ACSM3,ADH1B,AGAP2,AGMO,AGPS,AKR1B15,ALDH3B2,ALOX15,AVPR1A,B4GALT4,B4GALT5,BMX,CD74,CEACAM1,CNEP1R1,CPT1A,CPT1C,CSF1R,CYP1A1,CYP1A2,CYP26B1,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F3,CYP4F8,DDHD1,DHRS9,EFR3B,ELOVL4,ENPP6,ESYT3,ETFBKMT,ETNPPL,FA2H,FABP6,FADS6,FAM126B,FGF21,FGFR3,FPR2,GDPD1,GPAT4,GPC2,HTR2A,LIPH,LIPI,LPCAT2,NKX2-1,ORMDL3,P2RX7,PCYT1B,PHOSPHO1,PI4KAP2,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,PLCD1,PLIN5,PLP1,PLPP2,PLPP4,PLPPR4,PPM1L,PRKAR2B,PRKD2,PTGIS,PTGR1,PTK2,RBP1,RDH10,RDH12,RGN,SBF1,SERAC1,SFTPB,SGPP1,SIRT4,SLA2,SLC27A6,SLC44A3,SMPDL3B,SOCS4,SPNS2,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,THEM4,TLCD3B,UGCG,UGT8 |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 1116 | 109 | ALOX15,AZGP1,BTN2A2,BTNL9,BTRC,C5,CARD11,CD1D,CD209,CD22,CD300C,CD34,CD38,CD3D,CD40,CD74,CD86,CEACAM1,CFHR1,CLEC7A,CLU,COLEC10,CR2,CRTAM,CYFIP2,DRD2,ELMO2,FCN1,FFAR2,FGG,FGL1,FPR2,FYB2,GBP5,GCSAML,GPRC5B,GRB2,HAVCR2,HCK,HHLA2,HLA-DPB1,HLX,ICAM2,IL12A,IL23R,IL33,ITGAL,ITGAM,ITGB7,ITK,JAK2,JUN,KLK7,KLRC1,LAIR1,LGMN,LILRA2,LTF,MAP2K6,MAPK10,MUC20,MYO10,MYO1G,NCKAP1L,NECTIN2,P2RX7,PAX5,PELI1,PIANP,PIGR,PIK3AP1,PLCL2,PLPP4,PRKCZ,PRKD2,PSMD9,PTAFR,PTK2,RAB29,RAET1G,RNF125,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SELL,SEMA7A,SERPINB9,SFTPA2,SH2D1A,SLA2,SLAMF7,SMPDL3B,SPNS2,SUSD4,TESPA1,THEMIS2,TLR10,TLR5,TLR7,TRAC,TRAFD1,TXK,UBE2D1,ULBP1,ULBP3,VAV1,WAS |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 1703 | 143 | ADRA1A,ALOX15,AMER2,ANKRD6,ANXA9,APC2,ARHGAP44,BICC1,BTN2A2,BTRC,C1QL4,C5,CADM4,CALR,CBL,CCN3,CD22,CD34,CD74,CDH2,CEACAM1,CELF4,CHRD,CHRNA10,CLU,CST7,CX3CR1,CYP26B1,DACT3,DCC,DDIT4L,DEPDC5,DLL4,DRAXIN,DRD2,DUSP1,DUSP26,DUSP9,EIF4A3,ENHO,EPHB2,FGG,FKBP1B,FPR2,FZD9,GLI1,GPR37,GPR37L1,GRB2,GREM1,GREM2,GRIN1,HAVCR2,HEY2,HEYL,HIGD1A,HLX,IFT80,IGFBP2,IGSF1,IL1R2,IL33,IL7,ITGA6,KDM1A,KLHL31,KLKB1,KNG1,LDLRAD4,LGMN,LILRA2,LRFN5,LRP6,LTF,MAGI2,MAPK8IP1,MAPK8IP2,NCK2,NDRG2,NEURL1,NFATC4,NKD1,NKX2-1,NKX3-1,NOTCH3,NRXN1,NTN1,NXN,OTUD3,P2RX7,PALM3,PDE10A,PDE11A,PLAT,PLCL2,PLIN5,PRAME,PRKCZ,PSMD9,PTGER4,PTGIS,PTPN3,RB1CC1,RGMA,RGS10,RGS7,RGS9,RITA1,RNF125,RNF43,ROBO1,SAMHD1,SCG2,SCRIB,SCYL2,SEMA4D,SEMA7A,SERPINB9,SH2B3,SH3RF2,SHISA2,SIGLEC11,SLA2,SLC30A10,SLIT3,SMPDL3B,SNAI1,SOCS4,SOSTDC1,STAM2,STK3,SULF2,TAFA3,THEM4,TIMP3,TLE3,TNFAIP1,TNFSF10,TRAFD1,TSPAN15,UNC5B,VRK3,ZGPAT |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1813 | 960 | 99 | ACER2,ACER3,ACVRL1,ANXA9,AVPR1A,BMP6,CALR,CARD11,CASR,CCL26,CD1D,CD209,CD38,CD40,CD6,CD70,CD74,CD86,CDH3,CHP2,CHRD,CHRNA7,CHRNB2,CLEC11A,CLEC7A,COMP,CORO1A,CRLF1,CSF1R,CX3CR1,CXCR2,DISP3,DLL4,DRD2,EMP2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,FZD9,GAREM1,GDF9,GLI1,GPR37L1,GREM1,HAVCR2,HCK,HEY2,HHLA2,HLA-DPB1,HLX,HTR2A,IGFBP2,IL11,IL12A,IL23R,IL34,IL7,INSL4,ITGAX,JAK2,JUN,KDM1A,KLF5,LGMN,LIN28A,LTF,MAPK15,MATK,NCCRP1,NCK2,NCKAP1L,NES,NKX3-1,NOTCH3,NRP2,NTN1,PELI1,PPP1R16B,PRAME,PRKCZ,PRKD2,PTAFR,PTK2,S1PR3,SCG2,SCN5A,SERPINB7,SHC4,SLC25A27,SOX4,SPTA1,SRPK2,ST8SIA1,VASH2,ZNF703 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 1026 | 103 | ADCYAP1R1,ADRA1A,AKAP6,ALOX15,ALS2,ANKRD6,BCL2L11,C5,CALR,CARD11,CASR,CBL,CCL26,CD40,CD74,CD86,CDH2,CHP2,CHRNA7,CLEC16A,CSF1R,CX3CR1,DOK5,DRD2,DRD4,DUSP9,EDA,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GHR,GPR37,GPR37L1,GPR4,GPR65,GPRC5B,GRB2,GREM1,GUCY1A1,GUCY1A2,HAP1,HAVCR2,HTR2A,IAPP,IL11,JAK2,JUN,KSR1,LIN28A,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MUC20,NCK2,NKX3-1,NOS1,NOS1AP,NOX4,NRG2,P2RX7,P2RY1,P2RY8,PELI1,PIK3AP1,PIK3R5,PRKCZ,PRKD2,PTK2,RASGRF1,RB1CC1,ROBO1,RUNDC3A,S100A9,SCIMP,SEMA4D,SEMA7A,SEPTIN4,SH3RF2,SLC30A10,STK3,TENM1,TLR7,TNFRSF19,TNFSF10,TNFSF15,UNC5B,VAV1,ZDHHC13 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1813 | 1208 | 114 | ABCC1,ACTN2,ADCY4,AHR,AICDA,AKAP6,AMIGO1,AOC1,ATP1A3,ATP6V0B,ATP6V1C2,AVPR1A,BCL11A,BCL2L11,BMP6,BRINP1,BRINP2,CACNA2D1,CASR,CD40,CD6,CD86,CDH1,CEACAM1,CHRM4,CHRNA7,CHRNB2,CLEC7A,CLU,CPEB3,CPT1A,CX3CR1,CYBB,CYP26B1,DAPK1,DRD2,DRD4,ENHO,FFAR2,FGF21,FGFR2,FKBP1B,FPR2,GHR,GNAL,GNAO1,GPR37,GPR37L1,GRB2,GRIK5,GUCY1B1,HAVCR2,HCK,HCN2,HCN4,HTR2A,HTR3A,HTR3B,IL12A,INHBB,JAK2,JUN,KCNJ11,KCNMB1,KDM1A,KLF5,LGMN,LILRA2,LIN28A,LRP6,LTF,MAP2K6,MAP4K1,MRC1,MSX2,MT1F,NEURL1,NFATC4,NGFR,NKX6-1,NOS2,NOX4,NUGGC,P2RX7,P2RY1,POU4F1,PRKAR2B,PRKCZ,PTAFR,PTGER4,PTK2,PTPRN2,RARB,RDH12,RGN,RGS10,RGS9,RORB,RYR3,SCIMP,SLC29A1,SLC2A4,SLC30A10,SLC5A5,SLC6A4,SOX4,SSTR2,STK26,SYAP1,SYBU,TESC,VSNL1,VWA2,ZNF703 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 1454 | 128 | ABCC1,ACTN2,ACVR2A,ACVRL1,ADCY4,AHR,AKAP6,AMIGO1,AOC1,ATP1A3,ATP6V0B,ATP6V1C2,AVPR1A,BCL11A,BCL2L11,BMP6,CACNA2D1,CALR,CASR,CBL,CDH1,CEACAM1,CGN,CHRD,CHRM4,CHRNA7,CHRNB2,COMP,CORO1A,CPEB3,CX3CR1,CYBB,DDC,DLL4,DRD2,DRD4,DUSP1,EIF4A3,ENHO,EPB41L5,ESRRB,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FMOD,FOXA1,FPR2,GABRA1,GABRB2,GAREM1,GDF6,GDF9,GHR,GNAL,GNAO1,GRB2,GREM1,GREM2,HCN2,HCN4,HEYL,HNF4A,HTR2A,HTR3A,HTR3B,IGFBP2,INHBB,JAK2,JUN,KDM1A,KLF5,LDLRAD4,LGMN,LGR5,MAGI2,MSX2,NEO1,NEURL1,NGFR,NKX2-1,NKX3-1,NKX6-1,NOX4,NPFFR1,NPFFR2,NR2C1,NR2F1,NR5A2,NR6A1,P2RX7,P2RY1,POSTN,POU4F1,PRKAR2B,PRKCZ,PRKD2,PTAFR,PTGER4,PTK2,RARB,RGMA,RGS10,RGS9,RORB,RYR1,RYR3,SHISA2,SLC2A4,SLC30A10,SLC5A5,SLC6A4,SLIT3,SOSTDC1,SOX6,SPINT1,SSTR2,SULF2,SYAP1,TDGF1P3,TIGAR,TMEM100,UBE2D1,UGCG,VWA2,ZNF703 |
| GO_METAL_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 667 | 79 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATOX1,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,AVPR1A,BMP6,CACNA2D1,CACNB2,CALB2,CALR,CASR,CCR6,CCRL2,CD38,CD40,CD52,CHRNA10,CHRNA7,CNGB1,CORIN,CORO1A,CX3CR1,CXCR2,CYP4F12,DRD2,DRD4,FAM155A,FKBP1B,FPR2,FZD9,GNAT2,GPR4,GPR65,GRIN1,HAP1,HTR2A,IAPP,JAK2,KCNH2,KCTD17,KNG1,LRP6,LTF,MT1F,NEDD4L,NEO1,NOS1,P2RX7,P2RY1,P2RY8,PDZD8,PLCD1,PLCH1,PLCL2,PRND,PTGER4,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SLC12A8,SLC24A4,SLC25A27,SLC30A3,SLC40A1,SYPL2,TMPRSS3,TNNI3,TRPA1,TRPM8,XK |
| GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS | 0.0e+00 | 0.0e+00 | 1813 | 352 | 55 | ACHE,ADRA1A,ASIC1,CACNB2,CD34,CHRNB2,CHRNB4,CLEC7A,CLU,CPLX1,CSPG5,CX3CR1,DDC,DOC2B,DRD2,DRD4,ENPP6,GAD1,GLDC,GRIK5,HTR2A,JAK2,MCTP2,NOS1,NOS1AP,NOS2,NRXN1,NRXN2,P2RX7,P2RY1,PDE1B,PRKCG,PTGIS,PTPRN2,RAB3B,RGN,RIMS3,RPH3A,SCRIB,SDS,SLC18A2,SLC1A6,SLC29A1,SLC6A1,SLC6A11,SLC6A4,STX11,STX1A,SYN3,SYP,SYT2,SYT5,TPH1,TPH2,TRIM9 |
| GO_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 1813 | 1442 | 126 | ADA2,AHR,AICDA,AOC1,ARHGAP9,BACE2,BTN2A2,CAMK4,CARD11,CBL,CCR6,CD1D,CD209,CD22,CD38,CD3D,CD40,CD6,CD70,CD74,CD83,CD86,CEACAM1,CEBPA,CHRNB2,CHRNB4,CLEC7A,CLU,COMP,CORO1A,CR2,CST7,CXCR2,CYBB,CYP26B1,DHRS2,DLL4,DOCK8,DYNLL1,EOMES,FCN1,FGG,FGL1,FKBP1B,FPR2,FRMPD3,FZD9,GCA,GOLGA7,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,HP,HUWE1,HVCN1,IGFBP2,IL11,IL12A,IL23R,IL33,IL7,IST1,ITGAL,ITGAM,ITGAX,ITK,JAK2,JUN,KIF13B,KLF5,LAIR1,LILRA2,LRFN5,LTF,LY9,MAGT1,MAPK8IP1,MGAM,NCK2,NCKAP1L,NECTIN2,NFASC,ORMDL3,P2RX7,P2RY1,PELI1,PIGR,PIK3R5,PLA2G2D,PLCL2,POLM,PRKCG,PRKCZ,PTAFR,PTGER4,PTPRN2,PYGL,RAB29,RAB37,RAB44,RAB9B,RUNX3,S100A9,SELL,SELPLG,SH2B3,SIGLEC14,SLA2,SLAMF7,SOX4,SPN,SPTA1,SPTAN1,TAFA3,TCF7,TESPA1,TLR7,TMC6,TMEM30A,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 710 | 81 | ABHD5,ABHD6,ACER2,ACER3,ACHE,ACSM2A,ACSM3,AGAP2,AGMO,AGPS,AKR1B15,AKR1D1,ALDH3B2,ALOX15,AVPR1A,B4GALT5,BMP6,BMX,CD74,CEACAM1,CNEP1R1,CYB5R1,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP39A1,CYP46A1,DDHD1,DHH,DHRS9,ELOVL4,ENHO,ETNPPL,FA2H,FADS6,FGFR4,FPR2,GPAT4,HSD11B2,HSD17B6,HTR2A,LIPH,LIPI,LPCAT2,MALRD1,ORMDL3,OSBPL6,P2RX7,PCYT1B,PHOSPHO1,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLIN5,PLP1,PLPP2,PPM1L,PRKD2,PTGIS,RBP1,RDH10,RGN,SBF1,SERAC1,SGPP1,SIRT4,SLC44A3,SNAI1,SRD5A2,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,TFCP2L1,TLCD3B,UGCG,UGT8 |
| GO_GROWTH | 0.0e+00 | 0.0e+00 | 1813 | 990 | 99 | ACVRL1,ADRA1A,AKAP6,AKIRIN1,ANXA9,ARHGAP4,ATP8A2,AVPR1A,BCL11A,BCL2L11,BCL9,CACNA2D2,CACNG7,CCN3,CD38,CDKL3,CDKN2A,CEACAM1,CLSTN3,COMP,CSPG5,CYFIP2,DACT3,DCC,DCLK1,DMAP1,DRAXIN,DRD2,EAF2,EPB41L5,FGFR1,FGFR2,FGFR3,FTO,FZD9,GDF9,GHR,GLI1,GNG4,GPAT4,GREM1,HEY2,HLX,HNF4A,HOXB13,IGFBP2,IGSF11,IL7,ISLR2,IST1,KCNK2,KIF26B,KLF5,LGMN,LLPH,LRP6,MAGI2,MAPK11,MMP13,MSX2,MT1F,MYL2,NEDD4L,NKD1,NKX6-1,NPY1R,NRN1L,NRP2,NTN1,OLFM1,PLS1,POSTN,POU4F3,PRAME,PRKCZ,PTK2,RARB,RDH10,RND2,RPS6KA3,S100A9,SEMA4D,SEMA5B,SEMA7A,SGK2,SHTN1,SLC4A10,SLC6A4,SLIT1,SLIT3,SOCS4,STK3,SYT2,TFCP2L1,TLL2,TMPRSS4,TRPV2,VWA2,ZFYVE27 |
| GO_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 1296 | 117 | ACVRL1,AHI1,ALX4,ANKRD6,ANXA9,ATOH1,BMP6,BTRC,CAMSAP3,CASP14,CASR,CD34,CDH2,CDH3,CEACAM1,CHRD,CNFN,CNN3,CPT1A,CRLF1,CSF1R,CXCR2,CYP1A1,CYP26B1,DHRS9,DLL4,DMRT1,DSC2,DSC3,DSG3,EDA,EOMES,EPB41L5,FA2H,FGFR1,FGFR2,FOXA1,FRAS1,FREM2,GCM1,GLI1,GPAT4,GPR4,GRB2,GREB1L,GREM1,GRHL1,GSTM3,HESX1,HEY2,HEYL,HNF4A,HOXB13,HYDIN,IFT20,ITGAX,JAK2,JUN,KAZN,KIF26B,KLF5,KRT6B,KRT78,KRTAP9-6,LGR5,LRP6,MAGI2,MEOX1,MESP2,MSX2,MYCL,NFATC4,NKD1,NKX2-1,NKX3-1,NKX6-1,NR5A2,NTN1,NUP210L,PITX2,PODXL,POU4F3,PPP1R16B,PRKD2,PSMD9,RARB,RDH10,ROBO1,S1PR3,SALL2,SCEL,SCRIB,SCUBE1,SGPP1,SLC40A1,SLC4A5,SNAI1,SOSTDC1,SOX4,SPDEF,SPINT1,STK3,SULT2B1,TCF7,TDRD7,TFCP2L1,TGM5,TIGAR,TJP1,TMEFF2,TMEM100,TNFRSF19,UGCG,UPK1A,USH2A,VSIG1,ZNF703 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1164 | 109 | ABCC1,ABHD5,ACSL6,ACSM2A,ACSM3,ADH1B,ADHFE1,AKR1D1,ALOX15,ASRGL1,AVPR1A,AZIN2,B3GNT3,B4GALT4,B4GALT5,CD74,CEACAM1,CHST4,CHST6,CPT1A,CPT1C,CRYM,CSGALNACT1,CSPG5,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2B6,CYP2J2,CYP2S1,CYP39A1,CYP46A1,CYP4F12,CYP4F22,CYP4F3,CYP4F8,DDC,DHRS9,ELOVL4,ESRRB,ETFBKMT,FA2H,FADS6,FGFR4,FMOD,GAD1,GGTLC3,GHR,GLDC,GLS,GLS2,GPAT4,HAL,HNF4A,HTR2A,HYAL4,HYKK,ITIH5,LPO,MALRD1,MAT1A,MDH1,ME3,MTAP,NDNF,NOS1,NOS2,NOX4,NOXRED1,NR5A2,OAT,OAZ2,OGDHL,OSBPL6,P2RX7,PADI4,PLA2G4A,PLIN5,PLP1,PRELP,PRKAR2B,PSMD9,PTGIS,PTGR1,RBP1,RDH10,RGN,RIMKLA,RIMKLB,SDS,SIRT4,SLC22A11,SLC27A6,SPOCK2,SPOCK3,ST3GAL2,SULT2B1,SULT4A1,TARS3,TAT,THEM4,TIGAR,TPH1,TPH2,TPST1,VCAN,VNN2,XYLT1 |
| GO_NEUROTRANSMITTER_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 268 | 47 | ADRA1A,ASIC1,CACNB2,CHRNB2,CHRNB4,CPLX1,CSPG5,DDC,DOC2B,DRD2,DRD4,GABRQ,GAD1,GRIK5,HTR2A,MCTP2,NOS1,NRXN1,NRXN2,P2RX7,P2RY1,PRKCG,PTPRN2,RAB3B,RIMS3,RPH3A,SCRIB,SLC17A8,SLC18A2,SLC1A6,SLC29A1,SLC36A2,SLC36A3,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,SLC6A4,STX11,STX1A,SV2B,SYN3,SYP,SYT2,SYT5,TRIM9 |
| GO_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 634 | 75 | ABCB1,ABCC1,ACE,ANO3,ANO9,ASIC3,ATP8A2,AVPR1A,CA6,CALHM1,CASR,CEACAM1,CLCA3P,CLCN4,CLIC5,CPLX1,CPT1A,CYB5R1,CYB5R4,DRD2,DRD4,FGFR1,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GLRA3,GLS,GLS2,GRM7,HBA1,LRRC8C,LRRC8E,MAP2K6,NMUR1,NOS2,P2RX7,PLA2G2D,PLA2G4A,PTAFR,RTBDN,SLC12A8,SLC13A3,SLC16A10,SLC16A2,SLC16A5,SLC17A8,SLC1A4,SLC1A6,SLC22A11,SLC24A4,SLC27A6,SLC36A2,SLC36A3,SLC4A10,SLC4A5,SLC4A8,SLC52A3,SLC5A5,SLC66A2,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,SLCO2B1,STX1A,TMEM30A,TTYH2,XK,XKR4,XKR5,XPR1 |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 1124 | 106 | ABCC1,AKIRIN1,ANXA9,BMP6,BTRC,C5,CALR,CAMK1D,CARD11,CASR,CCL26,CCN3,CCR6,CD1D,CD209,CD34,CD6,CD74,CEACAM1,CEBPA,CLEC7A,CNGA1,CNGB1,CREB3L3,CRTAM,CST7,CXCR2,DAPK2,DRD2,DUSP1,FCN1,FFAR2,FGF18,FGFR1,FGG,FKBP1B,FPR2,GBP5,GPRC5B,GREM1,GRIN1,GUCA1B,GUCA1C,HAVCR2,HCK,HERC5,ICAM2,IFNLR1,IL12A,IL16,IL1R2,IL23R,IL33,ITGAM,JAK2,JAM3,KLK7,KLKB1,KNG1,LGMN,LILRA2,LRFN5,LTF,MAP2K6,MPP1,MUC20,NCKAP1L,NECTIN2,NMT2,NOS2,NRXN1,PELI1,PIK3AP1,PLAT,PRKCG,PRKD2,PSMD9,PTGER4,PTGIS,RAET1G,RGMA,RNF125,RNF216,ROBO1,RPS6KA3,S100A9,SAMHD1,SCG2,SCIMP,SCRIB,SEMA4D,SEMA7A,SERPINB9,SFTPA2,SH2B3,SH2D1A,SIGLEC11,SMPDL3B,TAFA3,TLR10,TLR5,TLR7,TRAFD1,TXK,UBE2D1,VAV1 |
| GO_HEART_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 295 | 49 | ACE,ADRA1A,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,AVPR1A,CACNA1G,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CELF2,CORIN,CYP2J2,DRD2,DSC2,FKBP1B,FXYD7,GNAO1,HCN4,HEY2,IRX5,JAK2,KCND1,KCND2,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNJ12,KCNJ5,KCNN2,MAP2K3,MAP2K6,MYL2,NEDD4L,NOS1,NOS1AP,NOX4,RYR1,RYR3,SCN3B,SCN4B,SCN5A,SGCZ,TNNI3,TNNT2 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1318 | 117 | ABHD6,ACVR1C,ACVRL1,ADGRB2,ADGRB3,ADRA1A,AKIRIN1,ANXA9,ARHGAP4,AVPR1A,BCL11A,BMERB1,BRINP1,BTN2A2,CALR,CCN3,CD34,CD38,CD74,CD83,CDH3,CDKL3,CEACAM1,CELF4,CEND1,CHRD,CHRNA7,COL4A3,CRMP1,CX3CR1,DACT3,DCC,DISP3,DLL4,DPYSL3,DRAXIN,DRD2,EAF2,EIF4A3,EPHB2,FGFR1,FGG,FKBP1B,FOXA1,GPR37L1,GPR4,GREM1,GUCY1A1,HAVCR2,HERC5,HEY2,HLX,IAPP,IL12A,IL1R2,IL23R,IL33,INHBB,ISM1,ITM2C,JAK2,KCNK2,KLKB1,KNG1,LAMA4,LDLRAD4,LGMN,LIN28A,LINGO1,LTF,LUC7L,MAP2K6,MAPK11,MSX2,MYLIP,NCKAP1L,NDRG2,NFATC4,NGFR,NKX2-1,NKX3-1,NKX6-1,NOTCH3,NR2F1,NTN1,P2RX7,PAEP,PLAT,PLCL2,PTGER4,PTK2,RAB29,RARB,RGMA,RGN,RNF125,RNF216,ROBO1,RORB,RTN4RL2,RUNX3,SEMA4D,SEMA7A,SH2B3,SLC6A4,SLIT1,SNAI1,SOSTDC1,SOX6,STAB1,STK3,TLE3,TLL2,TMEM176B,TPH1,TRPV3,ZBTB46 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1988 | 154 | ACTN2,ACVR2A,ACVRL1,ADCYAP1R1,AFAP1L2,AGAP2,AHI1,AHR,AICDA,ALX4,ARID3B,ARID3C,ATOH1,AVPR1A,BARX2,BCL9,BMP6,BORCS8-MEF2B,BTRC,C1orf61,CAMK4,CARD11,CD38,CD3D,CD40,CD74,CD86,CDH1,CDH3,CDK9,CEBPA,CHP2,CIITA,CLEC7A,CLU,CNEP1R1,CPEB3,CREB3L3,CYBB,DLX4,DMRT1,DRD2,DYRK1B,EAF2,EBF2,EGR2,EIF4A3,ELOF1,EOMES,ESRRB,FGFR1,FGFR2,FGFR4,FOXA1,FOXD2,FPR2,GCM1,GDF6,GLI1,GLIS3,GREM1,GRHL1,GRIN1,GTF2A1,GUCA1B,GUCA1C,HEY2,HEYL,HIVEP3,HLTF,HNF4A,HOXA1,HTR2A,IKZF5,IL11,IL33,ITGA6,JAK2,JUN,KDM1A,KLF5,LHX4,LHX6,LIN28A,LMX1B,LRP6,MAFA,MAP2K3,MAPK15,MAPRE3,MED12L,MED21,MEOX1,MRTFA,MYCL,MYRF,NCK2,NFATC4,NFE2L3,NGFR,NKX2-1,NKX3-1,NKX6-1,NOS1,NOS1AP,NOS2,NOTCH3,NOX4,NPAS1,NPAS3,NR2F1,NR5A2,NR6A1,P2RY1,PAX5,PAX9,PITX2,PLIN5,POU2F3,POU4F1,POU4F3,PPP1R3G,PRKD2,PSMD9,PTAFR,RARB,RASL11A,RDH10,RGMA,RGN,RMND1,RORB,RPS6KA3,RUNX3,SALL2,SLC40A1,SMARCA1,SNAI1,SOX4,SOX6,SPDEF,SPN,STAT4,TACC1,TAF1L,TBPL1,TESC,TLR7,TNFAIP1,TNFRSF8,TXK,VGLL2,WAS,ZBTB7C |
| GO_IMPORT_INTO_CELL | 0.0e+00 | 0.0e+00 | 1813 | 810 | 86 | ACHE,AHI1,ALOX15,ANXA9,ASGR1,ATP1A3,ATP1B1,ATP1B2,BMP2K,CACNA2D1,CALR,CBL,CD209,CD22,CD6,CEACAM1,CLEC7A,CLU,CXCR2,DRD2,DRD4,FAM155A,FCHO1,FCN1,FPR2,GHR,GRB2,GREM1,GULP1,HBA1,HCN2,HCN4,HP,ILDR1,ITGAM,KCNH2,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNK9,LRP6,LTF,MAGI2,MAPK15,MAPK8IP1,MAPK8IP2,MIA3,MRC1,NCKAP1L,NEDD4L,NEURL1B,NOS1,NOSTRIN,PSTPIP1,RAB3B,RHOV,SCAMP5,SCGB3A2,SCRIB,SCYL2,SLC12A8,SLC18A2,SLC1A6,SLC29A1,SLC2A4,SLC6A1,SLC6A11,SLC6A4,SNX2,STAB1,STX1A,SYP,SYT2,SYT5,TMPRSS15,TMPRSS2,TMPRSS3,TMPRSS4,TRIP10,TUB,WAS,XKR4,XKR5 |
| GO_REGULATION_OF_BLOOD_CIRCULATION | 0.0e+00 | 0.0e+00 | 1813 | 299 | 49 | ACE,ADRA1A,ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,AVPR1A,CACNA1G,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CASR,CD38,CELF2,CORIN,CYP2J2,DRD2,DSC2,FGG,FKBP1B,FXYD7,GNAO1,HCN4,HEY2,HTR2A,IRX5,JAK2,KCND1,KCND2,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNJ12,KCNJ5,KCNN2,MYL2,NOS1,NOS1AP,PTAFR,RYR1,RYR3,SCN3B,SCN4B,SCN5A,TNNI3,TNNT2 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1813 | 1258 | 113 | ACE,ADRA1A,AFAP1L2,ART1,ASGR1,ASPHD2,BCL11A,BMP6,BMX,CADM4,CAMK4,CBL,CD40,CD74,CNTN1,CPA4,CRLF1,CSF1R,DCLK1,DMAP1,DOK7,DPY19L2,DPY19L2P2,DYDC2,DYRK1B,EGR2,EPHA6,EPHB2,EPHB3,ETFBKMT,FGFR1,FGFR2,FGFR3,FGFR4,FKBP1B,FLT4,GALNT13,GALNT16,GHR,GOLGA7,GPRC5B,GREM1,HCK,HTR2A,IL11,IL12A,IL23R,IL7,ITK,JAK2,KDM1A,KPNA7,LMTK2,MAGT1,MAP2K3,MAP2K6,MAP4K1,MAP6D1,MARK1,MAST1,MATK,MKNK1,NCK2,NDNF,NEURL1,NMT2,NOS1,NOS1AP,NOS2,NOX4,OPRD1,PADI3,PADI4,PAX5,PLCL2,PPIAL4G,PRDM6,PRKCG,PRKCZ,PRKD2,PRMT8,PTK2,RAB3B,RPS6KA3,S100A9,SBK1,SEMA4D,SGK2,SH2B3,SH2D3A,SH2D3C,SIRT4,SOCS4,SOX4,SPOCK2,SPOCK3,SRCIN1,STT3B,STX1A,STYK1,TAF1L,TENM1,TESK2,TPST1,TSSK1B,TTLL7,TUSC3,TXK,VRK3,ZDHHC11B,ZDHHC15,ZDHHC23,ZGPAT |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 942 | 94 | ACE,ACTR3C,ACVRL1,ADD2,ADGRB2,ADGRB3,ADGRL1,AKIRIN1,ALOX15,AMIGO1,ARHGAP40,ARHGAP44,ARHGAP6,ARHGEF10,BCL2L11,BIK,CAMSAP3,CBLN2,CCL26,CHRNB2,CLEC7A,CLSTN3,CLU,CORO1A,CRACD,DCDC2,DPYSL3,EPB41L5,EPHB2,EPHB3,ESAM,FCHSD1,GBP5,GPBAR1,GPR65,GRB2,GREM1,GRIN1,HAP1,HCK,IAPP,IFT20,IL1RAPL1,JAM3,KCTD17,KLF5,LCMT1,LDLRAD4,LRFN1,LRFN5,MALSU1,MAPK15,MAPRE3,MDGA1,MYO10,NCK2,NCKAP1L,NEURL1,NOX4,NRXN1,NTN1,NTNG2,OCLN,OPRD1,ORMDL3,P2RX7,PIP4K2A,PODXL,PPP1R16B,PRKCZ,PTGER4,PTK2,RAB17,RAP1GAP,SCFD1,SCIN,SEC22B,SEMA4D,SLIT1,SLITRK2,SLITRK3,SNAI1,SPTA1,SPTAN1,SPTB,STX1A,TBC1D30,TENM1,TJP1,TMEFF2,TPPP3,TRIM9,TUBB4A,WAS |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1813 | 1930 | 150 | ACTN2,ADAM22,AGPS,AHI1,AKAP6,ANXA9,AP1B1,AP1S3,AP3B2,ARHGAP44,ARL14,ARL6,ATP1B1,BCL2L11,CABP1,CACNB2,CACNG7,CALR,CAMSAP3,CD74,CDH1,CDH2,CEP83,CHP2,CLMN,CLU,CNEP1R1,CNGB1,CPLX1,CRIPT,DCLK1,DDX25,DMAP1,DRD4,DYNLL1,EFR3B,EGR2,EIF4A3,EMP2,EPHB2,ESAM,EVI5,EXOC8,FAM126B,FCN1,FYB2,FZD9,GBP5,GFY,GGA2,GOLGA7,GPC2,GRIK5,GRIN1,GRTP1,HAP1,HEY2,HTR2A,HUWE1,IFT20,IFT80,ITGAL,ITGAM,ITGB7,JAM3,KCNIP4,KCNJ11,KDM1A,KIF13A,KIF13B,KIF5A,KIF5C,KLF5,KPNA1,KPNA5,KPNA7,LAMP3,LRP6,LRRC15,MAGI2,MAP7,MAPK10,MAPK15,MAPRE3,MARCHF5,MESD,MIA3,NAPG,NEDD4L,NEURL1B,NFASC,NGFR,NOS2,NRXN1,NRXN2,OAZ2,P2RY1,PEX5L,PIGR,PLS1,PRKCZ,RAB17,RAB29,RAB33A,RAB37,RAB3B,RAB44,RAB9B,REEP1,RGPD3,RIC3,RPH3A,SCG3,SCIN,SCN3B,SCRIB,SGSM1,SGSM3,SGTB,SH3TC2,SIRT4,SNX2,STAM2,STX11,STX12,STX1A,STX6,SYMPK,SYTL5,TBC1D1,TBC1D29P,TBC1D30,TENM1,TESC,TMED6,TMEFF2,TMEM30A,TOR1AIP2,TOR1B,TSPAN15,TSPAN33,TSPAN5,TUB,UBE2D1,UGT8,USP6NL,ZDHHC11B,ZDHHC15,ZDHHC23,ZFYVE27 |
| GO_EXOCYTOSIS | 0.0e+00 | 0.0e+00 | 1813 | 900 | 91 | ACTN2,ADA2,ADRA1A,AOC1,ARHGAP44,ARHGAP9,CACNA1G,CACNA1I,CACNB2,CBL,CDK5R2,CEACAM1,CHRNB2,CHRNB4,CLU,CORO1A,CPLX1,CSPG5,CXCR2,CYB5R1,CYBB,DOC2B,DRD2,DYNLL1,ENDOD1,EXOC8,F5,FCN1,FGG,FPR2,FRMPD3,GCA,GOLGA7,GRIK5,HAP1,HCK,HP,HTR2A,HUWE1,HVCN1,IL1RAPL1,IST1,ITGAL,ITGAM,ITGAX,KNG1,LAIR1,LGI3,LTF,MAGT1,MGAM,MIA3,MYO1G,NCKAP1L,NFASC,ORMDL3,P2RX7,P2RY1,PIGR,PRKCG,PTAFR,PTPRN2,PYGL,RAB37,RAB3B,RAB44,RAB9B,RIMS3,S100A9,SCAMP5,SCFD1,SCG3,SCIN,SCRIB,SELL,SEPTIN4,SIGLEC14,SPTAN1,SRCIN1,STX11,STX1A,SYP,SYT13,SYT2,SYT5,SYTL5,TIMP3,TMC6,TMEM30A,TRIM9,VSNL1 |
| GO_PEPTIDE_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 641 | 74 | ABCC8,ACHE,ACVR1C,BMP6,BMP8A,BTN2A2,C5,CACNA2D2,CARD11,CASR,CCN3,CD22,CD34,CD38,CD40,CD74,COMP,CPLX1,CPT1A,CRTAM,CSF1R,CYB5R4,DISP1,DNAJC1,DOC2B,DRD2,DRD4,ENHO,FAM3B,FCN1,FFAR2,FGG,FKBP1B,GBP5,HAVCR2,HNF4A,IL1R2,IL33,ILDR1,ILDR2,INHBB,JAK2,KALRN,KCNJ11,LILRA2,MAFA,MAPK11,MBP,MIA3,NKX6-1,NOS2,NOX5,OLFM2,P2RX7,PAEP,PCSK5,POSTN,PRKCZ,PSMD9,PTGER4,PTPRN2,RAB3B,SCAMP5,SCG2,SIRT4,SLC16A10,SLC16A2,SOX4,SRCIN1,STX1A,SYBU,TLR10,TLR5,VSNL1 |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 1175 | 107 | ACTN2,ACVRL1,ADGRB2,ADGRB3,ADRA1A,AHI1,AHR,AKAP6,ANGPTL6,ANXA9,AP1B1,BICC1,C1orf127,C5,CALR,CCN3,CD34,CD40,CDH2,CEACAM1,CHRNA7,COL4A3,COMP,CX3CR1,CXCR2,CYBB,DLL4,EMP2,EOMES,EPHB2,EPHB3,FGF18,FGFR1,FGFR2,FLT4,FREM2,GLI1,GPR4,GREB1L,GREM1,HEY2,HEYL,HOXA1,HOXB13,HS6ST1,IFT20,ISM1,ITGAX,JAM3,JUN,KCNK2,KLF5,LRP6,MAPK11,MESP2,MIA3,MSX2,MYL2,MYO18B,NDNF,NFATC4,NGFR,NKX3-1,NOTCH3,NOX4,NOX5,NPY1R,NRP2,NXN,OLFM1,PCSK5,PDLIM3,PITX2,PLCD1,PLXDC1,POU4F1,PPP1R16B,PRKD2,PTGIS,PTK2,RARB,RB1CC1,RBM20,RBM24,ROBO1,RYR1,SCG2,SCN5A,SCUBE1,SERPINB7,SGCZ,SLIT3,SNAI1,SOX4,SOX6,SPINT1,SRPK2,STAB1,STK3,SYPL2,TDGF1P3,TMEM100,TNNI3,TNNT2,TSPAN12,UNC5B,VASH2 |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 1813 | 1061 | 100 | ABCB1,ABCC1,ACER2,ADCYAP1R1,ADRA1A,AHR,AMIGO1,AOC1,ASIC1,BCL11A,CALHM1,CALR,CBL,CD38,CD40,CDH1,CDH3,CDK9,CHRM4,CHRNA7,CHRNB2,CHRNB4,CPT1A,CYBB,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,DDC,DMAP1,DRD2,DRD4,DUSP1,FGF21,FGFR2,FKBP1B,GAD1,GDF9,GNAL,GNAO1,GPR37,GPR37L1,GRIN1,GUCY1B1,HBA1,HBE1,HBG2,HP,HSD11B2,HTR2A,HTR3A,HTR3B,IGFBP2,JUN,KCNC1,KCNH2,KCNJ11,KCNMB1,MAP2K6,MAP4K1,MAPK15,NCKAP1L,NKX3-1,NKX6-1,NOS1,NOS2,P2RX7,P2RY1,PDE1B,PRKAR2B,PRKCG,PTAFR,PTGR1,RAB3B,RGS10,RGS9,RTBDN,RYR1,RYR3,SELL,SLC13A3,SLC17A8,SLC18A2,SLC1A6,SLC2A4,SLC36A2,SLC36A3,SLC52A3,SLC6A1,SLC6A11,SLC6A4,SLIT3,STK26,SYT13,SYT2,SYT5,TIMP4,TMEM30A,TRPA1 |
| GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 525 | 65 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATP1B1,ATP2A3,ATP2B2,AVPR1A,CACNA2D1,CACNB2,CALB2,CALR,CASR,CCR6,CCRL2,CD38,CD40,CD52,CHRNA10,CHRNA7,CNGB1,CORO1A,CX3CR1,CXCR2,DRD2,DRD4,FAM155A,FKBP1B,FPR2,FZD9,GNAT2,GPR4,GPR65,GRIN1,HAP1,HTR2A,IAPP,JAK2,KCTD17,KNG1,LRP6,MT1F,NOS1,P2RX7,P2RY1,P2RY8,PDZD8,PLCD1,PLCH1,PLCL2,PTGER4,RGN,RIC3,RYR1,RYR3,S100A9,S1PR3,SLC24A4,SLC25A27,SLC30A3,SYPL2,TNNI3,TRPA1,TRPM8,XK |
| GO_BEHAVIOR | 0.0e+00 | 0.0e+00 | 1813 | 598 | 70 | ADAM22,ADGRB3,AHI1,ALS2,ASIC1,ASTN1,ATP8A2,AVPR1A,BRINP1,CAMK4,CASR,CEND1,CHRNA7,CHRNB2,CHRNB4,CPEB3,CPT1A,CX3CR1,DRD2,DRD4,EGR2,EIF4A3,EPHB2,FZD9,GAD1,GCNT4,GLS,GNAO1,GNB1L,GPR37,GRID1,GRIN1,HOXA1,HTR2A,IAPP,IFT20,JUN,KALRN,KCND2,KCNK2,LGMN,LPAR5,MAPK8IP2,MYH14,NFATC4,NKX2-1,NPAS1,NPY1R,NRXN1,NRXN2,NRXN3,OLFM2,OPRD1,OPRK1,P2RY1,PAX5,PDE1B,PMCHL2,POU4F1,PREX2,PRKAR2B,PRKCG,PRKCZ,PTPRZ1,RASGRF1,SLC18A2,SLC4A10,SLC6A1,SLC6A4,STRBP |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 569 | 68 | ADCYAP1R1,ADRA1A,ALS2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ARHGEF3,CADM4,CBL,CDKN2A,CHN2,CNKSR1,CYTH4,DIRAS3,DOCK8,EPHB2,FGD2,FGD5,GPR4,GPR65,GRB2,JAK2,JUN,KALRN,KNDC1,KSR1,KSR2,MAPK11,MCF2L,MCF2L2,NGFR,NTN1,P2RY8,PLEKHG1,PLEKHG4B,PREX2,PSD,PSD2,RAB17,RAB29,RAB33A,RAB37,RAB3B,RAB44,RAB9B,RALGAPB,RALGPS1,RAP1GAP,RASGRF1,RHOV,RND2,ROBO1,RUNDC3A,SGSM3,SH2D3A,SH2D3C,SHTN1,SRGAP3,STARD8,TNFAIP1,TRIP10,VAV1,WAS |
| GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 499 | 63 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ASIC1,ATP1B1,ATP2A3,ATP2B2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CAMK2B,CASR,CHRNA10,CHRNA7,CHRNB2,CLCA3P,CORO1A,DRD2,DRD4,FAM155A,FGF14,FKBP1B,GEM,GNAO1,GRIN1,HAP1,HTR2A,IL16,IL1RAPL1,LILRA2,MAGT1,MRLN,NIPAL1,NMUR1,NOS1,NOS1AP,OPRD1,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,RGN,RGS9,RYR1,RYR3,SLC24A4,SLC30A10,SLC30A3,SLC40A1,SLN,TRPA1,TRPM8,TRPV2,TRPV3,TUSC3,ZDHHC13 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 1220 | 108 | ACTN2,ACTR3C,ADGRB2,ADGRB3,ADGRL1,AHI1,AKIRIN1,ALOX15,AMIGO1,ANXA9,ARHGEF10,ATP8A2,BCL2L11,BIK,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CBL,CBLN2,CCL26,CDK9,CDKL3,CFL2,CHODL,CLEC16A,CLEC7A,CLSTN3,CLU,CNTN1,CORO1A,CPEB3,CRACD,CSPG5,DDHD1,DMRT1,DOC2B,DPYSL3,DRD2,EPB41L5,EPHB2,EPHB3,FBXO31,FCHSD1,FGFR1,FGG,FKBP1B,GBP5,GCM1,GPC2,GPR65,GRB2,GREM1,HAP1,HCK,HUWE1,IL1RAPL1,ISLR2,IST1,ITGA6,KALRN,KCTD17,KDM1A,KPNA7,LLPH,MAGI2,MAP6,MAPK15,MAPK8IP1,MAPK8IP2,MARCHF5,MESD,MSX2,NCK2,NCKAP1L,NDNF,NEDD4L,NES,NEURL1,NGFR,NOS1,NOX4,NRXN1,NTN1,P2RX7,PIP4K2A,PRDM6,PRKD2,RND2,ROBO1,S100A9,SCIN,SCYL2,SEMA4D,SEMA7A,SHTN1,SLITRK2,SLITRK3,SLN,SYT2,TENM1,TMEM30A,TNFSF10,TPPP3,TRPV2,WAS,ZFYVE27 |
| GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 277 | 45 | ABCB1,ACTN2,ADCYAP1R1,AKAP6,AMIGO1,ANXA9,ATP1B1,ATP1B2,ATP8A2,AVPR1A,CACNA2D1,CACNB2,CASR,CHRNB2,CNTN1,DRD2,DRD4,EPHB2,FGF14,GRIN1,HAP1,HTR3A,KCNC1,KCNE5,KCNH2,KCNJ11,KCNMB1,LILRA2,MAP2K6,NOS1,NOS1AP,P2RX7,P2RY1,PTAFR,RAB3B,RGN,RGS9,SCN3B,SCN4B,SCN5A,SLC6A1,SLC6A4,TESC,TRPV2,TRPV3 |
| GO_SYNAPSE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1813 | 178 | 36 | ACHE,ADD2,ADGRB2,ADGRB3,ADGRL1,AMIGO1,CBLN2,CDH1,CDH2,CHRNB2,CLSTN3,DRD2,EPHB2,EPHB3,GABRA1,GABRB2,GRIN1,IL1RAPL1,LRFN1,LRFN5,MAGI2,MDGA1,NRXN1,NRXN2,NTN1,NTNG2,POU4F1,PTK2,RAB17,RAB29,SDK2,SEMA4D,SLIT1,SLITRK2,SLITRK3,SPOCK2 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 1163 | 104 | ACVRL1,ADGRB2,ADGRB3,AHI1,AMIGO1,ANKRD6,ARHGAP15,ARHGAP4,ARHGAP44,BCL11A,C5,CACNG7,CALR,CAMK2B,CD34,CD40,CDH2,CDKL3,CEACAM1,CHODL,CHRNA7,CHRNB2,COL4A3,CORO1A,CSF1R,CSPG5,CX3CR1,CXCR2,CYBB,DCC,DDHD1,DLL4,DRAXIN,EMP2,EPHB2,EPHB3,FBXO31,FGD2,FGD5,FGF18,FGFR1,FGFR2,FGG,FLT4,GCM1,GLI1,GPR4,GREM1,GRIN1,HCK,HEY2,HNF4A,IL1RAPL1,ISLR2,ISM1,IST1,ITGAX,KALRN,KIF13B,KNDC1,LINGO1,LRRC4C,LZTS1,MAGI2,MAP6,MARCHF5,MBP,MYH14,MYO10,NEDD4L,NFATC4,NGFR,NKD1,NKX6-1,NTN1,OLFM1,P2RY1,PAX9,PDZD8,POSTN,PPP1R16B,PRKD2,PSMD9,PTGIS,PTK2,RHOV,RND2,ROBO1,SEMA4D,SEMA7A,SHTN1,SP6,SPTA1,SRCIN1,STAB1,SULF2,SYT2,TMEM100,TRPV2,TSPAN12,VASH2,WASF3,XK,ZFYVE27 |
| GO_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1813 | 769 | 80 | ADRA1A,ALOX15,ANKRD6,BMP6,BMP8A,BTN2A2,C1QL4,C5,CASR,CCL26,CD40,CD74,CDH2,CEACAM1,CHRNA10,CHRNA7,CSF1R,DOK5,DRD2,DRD4,DUSP1,DUSP26,DUSP9,EPHB2,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GDF9,GHR,GPR37,GPR37L1,GRB2,HAVCR2,HTR2A,IAPP,IL11,INHBB,INHBC,JAK2,JUN,KLHL31,KSR1,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MUC20,NDRG2,NOX4,NPFFR2,P2RX7,P2RY1,PIK3R5,PRKCZ,PRKD2,RB1CC1,ROBO1,SCIMP,SEMA7A,SH2B3,SH3RF2,SLC30A10,STK3,TENM1,TIMP3,TNFRSF19,VRK3 |
| GO_DEVELOPMENTAL_GROWTH | 0.0e+00 | 0.0e+00 | 1813 | 677 | 74 | ADRA1A,AKAP6,AKIRIN1,ANXA9,ARHGAP4,ATP8A2,BCL11A,BCL2L11,BCL9,CACNA2D2,CACNG7,CCN3,CDKL3,COMP,CYFIP2,DCC,DCLK1,DRAXIN,DRD2,EPB41L5,FGFR1,FGFR2,FGFR3,FTO,FZD9,GDF9,GHR,GLI1,GPAT4,HEY2,HLX,IL7,ISLR2,IST1,KCNK2,KIF26B,KLF5,LGMN,LLPH,LRP6,MAGI2,MAPK11,MMP13,MSX2,NEDD4L,NKD1,NKX6-1,NPY1R,NRN1L,NRP2,NTN1,OLFM1,PLS1,POSTN,POU4F3,PRKCZ,PTK2,RARB,RDH10,RND2,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLC4A10,SLC6A4,SLIT1,SLIT3,STK3,SYT2,TLL2,TRPV2,VWA2,ZFYVE27 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 0.0e+00 | 0.0e+00 | 1813 | 503 | 62 | ACE,ACTN2,ACTR3C,ADD2,ADRA1A,ALOX15,ALS2,ARHGAP4,ARHGAP40,AVPR1A,CASR,CCL26,CD38,CDKL3,CFL2,COMP,CORO1A,CRACD,DCC,DRAXIN,ESAM,FCHSD1,FGG,GRB2,GUCY1A1,HCK,HTR2A,ISLR2,IST1,KCNMB1,KDM1A,KNG1,NCK2,NCKAP1L,NKX6-1,NOS1,NTN1,OLFM1,P2RX7,P2RY1,PLEKHH2,PLS1,PTAFR,RAB3B,RB1CC1,RND2,SCIN,SEMA4D,SEMA7A,SHTN1,SLC12A8,SLC6A4,SPTA1,SPTAN1,SPTB,TENM1,TMEM123,TRPV2,VAV1,WAS,XK,ZFYVE27 |
| GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 547 | 65 | ACTN2,ADRA1A,AHI1,ALOX15,ANXA9,ARHGAP44,BMP2K,CACNA1G,CACNA1I,CACNB2,CALR,CAMK1D,CBL,CD22,CDH2,CDK5R2,CEACAM1,CHRNB2,CLEC7A,CLU,CORO1A,CPLX1,CSPG5,DOC2B,DRD2,DRD4,FGF14,FGG,FPR2,GREM1,GRIK5,HAP1,HCK,HTR2A,IL1RAPL1,IL2RB,ITGAM,LGI3,MAGI2,MAPK15,MAPK8IP1,MAPK8IP2,NCKAP1L,NEDD4L,NRXN1,P2RY1,PRKCG,PTAFR,RAB29,RAB3B,RIMS3,SCAMP5,SCFD1,SCRIB,SCYL2,SEPTIN4,SLC2A4,STX1A,SYP,SYT13,SYT2,SYT5,TRIM9,TUB,VSNL1 |
| GO_HEAD_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 774 | 80 | ADGRL2,AHI1,AMIGO1,ARL6,ATOH1,AVPR1A,BCL2L11,BMERB1,C21orf91,CDH1,CDH2,CDK5R2,CEND1,CHRD,CHRNB2,CNTN1,CSF1R,CXCR2,DCLK1,DRAXIN,DRD2,DYNLL1,EFNA2,EGR2,EML1,EOMES,EPHB2,EPHB3,EXT1,FGFR1,FGFR2,GLI1,GNAO1,GPR37L1,GRIN1,HAP1,HESX1,HYDIN,ITGAM,JHY,KCNC1,KDM1A,KIF27,KNDC1,LHX6,LRP6,MAP1S,MAST1,MBP,MDGA1,METTL14,MYO16,NDRG2,NES,NEURL1,NKX2-1,NOTCH3,NRP2,PAX5,PAX9,PITX2,PLP1,POTEE,POU4F1,RARB,ROBO1,RTN4RL2,SCN5A,SCRIB,SEMA7A,SLC17A8,SLC4A10,SLC6A11,SLC6A4,SLIT1,SMARCA1,SSTR2,SYPL2,TACC1,TSPAN2 |
| GO_NEURON_PROJECTION_GUIDANCE | 0.0e+00 | 0.0e+00 | 1813 | 282 | 45 | ATOH1,BOC,CRMP1,CSF1R,CYFIP2,DCC,DOK5,DPYSL5,DRAXIN,EFNA2,EGR2,ENAH,EPHA6,EPHB2,EPHB3,EXT1,GFRA2,GRB2,IGSF9,KIF5A,KIF5C,LHX4,NCAM1,NEO1,NFASC,NKX2-1,NRP2,NRXN1,NRXN3,NTN1,NTN5,POU4F3,PTK2,RAP1GAP,ROBO1,SEMA4D,SEMA5B,SEMA7A,SLIT1,SLIT3,SPTA1,SPTAN1,SPTB,TMEFF2,UNC5B |
| GO_REGULATION_OF_CELL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 491 | 61 | ADGRB3,AMIGO1,ARHGAP15,ARHGAP4,ARHGAP44,BCL11A,CACNG7,CALR,CAMK2B,CDH2,CDKL3,CHODL,CHRNB2,CORO1A,CSF1R,CSPG5,DCC,DRAXIN,EPHB2,EPHB3,FBXO31,FGD2,FGD5,FGG,GRIN1,HCK,IL1RAPL1,ISLR2,IST1,KALRN,KIF13B,KNDC1,LINGO1,LRRC4C,LZTS1,MAP6,MYH14,MYO10,NEDD4L,NFATC4,NGFR,NKX6-1,NTN1,OLFM1,P2RY1,PDZD8,POSTN,PTK2,RHOV,RND2,ROBO1,SEMA4D,SEMA7A,SHTN1,SPTA1,SRCIN1,SYT2,TRPV2,WASF3,XK,ZFYVE27 |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 622 | 70 | AMER2,ANKRD6,APC2,ARL6,ATP6V1C2,BCL9,BICC1,BTRC,CDH2,CDH3,CELF4,CHRNA10,CHRNA7,CHRNB2,CHRNB4,CPZ,DACT3,DCDC2,DRAXIN,DRD2,DRD4,EDA,EIF4A3,FGFR2,FZD9,GLI1,GLRA3,GNAO1,GNAT2,GPRC5B,GREM1,GRIK5,GRIN1,GSKIP,IFT20,IFT80,IGFBP2,IGSF11,INSYN1,ITGAM,LGR5,LRP6,MAGI2,MAPK8IP1,MAPK8IP2,MARK1,MESD,NDRG2,NFATC4,NKD1,NRXN1,NXN,P2RX7,PRKCZ,PSMD9,RNF43,SCEL,SCYL2,SHISA2,SLC29A1,SOSTDC1,SOX4,STK3,STX1A,SULF2,TCF7,TCF7L1,TLE3,TSPAN12,ZNF703 |
| GO_TUBE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 1122 | 101 | ACVRL1,ADGRB2,ADGRB3,AHI1,ALX4,ANGPTL6,ANXA9,BCL2L11,BTRC,C5,CASR,CCN3,CD34,CD40,CDH2,CEACAM1,CEBPA,CHRD,CHRNA7,COL4A3,COMP,CRLF1,CSF1R,CX3CR1,CXCR2,CYBB,CYP1A1,CYP1A2,DLL4,EDA,EMP2,EOMES,EPB41L5,EPHB2,EPHB3,FGF18,FGFR1,FGFR2,FLT4,FOXA1,GLI1,GPR4,GREB1L,GREM1,HESX1,HEY2,HEYL,HLX,HOXA1,HOXB13,HS6ST1,ISM1,ITGA6,ITGAX,JAM3,JUN,KIF26B,KLF5,LGR5,LRP6,MIA3,MSX2,MYO18B,NDNF,NFATC4,NGFR,NKX2-1,NKX3-1,NOTCH3,NOX5,NRP2,NTN1,PCSK5,PLCD1,PLXDC1,PODXL,PPP1R16B,PRKD2,PTGIS,PTK2,RAD21L1,RARB,RDH10,ROBO1,SALL2,SCG2,SCRIB,SOSTDC1,SOX4,SPDEF,SPINT1,SRPK2,STAB1,STK3,TCF7,TIGAR,TMEM100,TNNI3,TSPAN12,UNC5B,VASH2 |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 1177 | 104 | ACTN2,ACVRL1,ADGRB2,ADGRB3,AHI1,ANGPTL6,ANXA9,ARL6,ATP8A2,BCL2L11,BMERB1,C5,CCN3,CD34,CD40,CDK5R2,CEACAM1,CEND1,CFL2,CHRD,CHRNA7,COL4A3,CX3CR1,CXCR2,CYBB,DLL4,DYRK1B,EDA,EGR2,EMP2,EOMES,EPB41L5,EPHB2,EPHB3,FGF18,FGFR1,FGFR2,FLT4,FOXA1,GCM1,GPR4,GRB2,GREM1,HESX1,HEY2,HEYL,HOXA1,HOXB13,HS6ST1,ISM1,ITGA6,ITGAX,JAM3,JUN,KIF26B,KLF5,KNDC1,LRP6,MEOX1,MESP2,MIA3,MSX2,MYL2,NDNF,NECTIN2,NFASC,NFATC4,NGFR,NKD1,NKX2-1,NKX3-1,NOS1,NOTCH3,NOX5,NRP2,OLFM1,PLCD1,PLXDC1,PNLDC1,PODXL,PPP1R16B,PRKD2,PTGIS,PTK2,RDH10,ROBO1,SCG2,SCRIB,SDK2,SLC24A4,SLC40A1,SNAI1,SOX4,SPINT1,SRPK2,STAB1,STK3,TBPL1,TMEM100,TNNT2,TSPAN12,UGT8,UNC5B,VASH2 |
| GO_MULTICELLULAR_ORGANISMAL_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 204 | 38 | ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,AVPR1A,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CHRNB4,CORIN,DSC2,FKBP1B,FXYD7,HCN4,JAM3,KCND1,KCND2,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNJ12,KCNJ5,KCNN2,MYH14,NFASC,NOS1,OTOA,RYR1,RYR3,SCN3A,SCN3B,SCN4B,SCN5A |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1813 | 974 | 92 | ACE,ACVR2A,ADAM28,ADCYAP1R1,AZIN2,BCL2L11,BIK,BMP6,CALR,CBL,CCR6,CDYL,CEBPA,CELF4,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,EAF2,EOMES,FAM9A,FAM9B,FGFR2,FOXA1,FSCN3,GCM1,GDF9,GLI1,GRB2,GREB1L,HEY2,HNF4A,HOOK1,HOXB13,HS6ST1,IFT20,INHBB,IRX5,JAM3,LGR5,LHX4,LIN28A,LRGUK,LRP6,MC2R,METTL14,NECTIN2,NEURL1,NKX2-1,NKX3-1,NUP210L,PAEP,PARP11,PAX5,PCDH12,PCYT1B,PIWIL3,PLAC1,PLCD1,PTCHD3,PTGIS,PTK2,RAD21L1,RDH10,RGN,SBF1,SEPTIN4,SEPTIN6,SLIT3,SNAI1,SPANXA1,SPATA32,SPEF2,SPINT1,SRD5A2,SSTR2,STK3,STRBP,TBPL1,TCF7,TDRD7,TDRKH,TDRP,TESK2,TEX11,TNFSF10,TSNAX,TSSK1B,VASH2 |
| GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 0.0e+00 | 1813 | 274 | 44 | ADGRL1,AMIGO1,CD209,CD6,CDH1,CDH15,CDH2,CDH3,CDHR3,CEACAM1,CLDN10,CLDN23,CLSTN3,CRB1,DSC2,DSC3,DSG3,ESAM,IGSF11,IGSF9,IL1RAPL1,ITGAL,ITGAM,LRFN5,LRRC4C,MBP,MDGA1,NECTIN2,NRXN1,NTNG2,PCDH10,PCDH12,PCDH20,PCDHA10,PCDHA4,PCDHA5,PCDHGA3,ROBO1,SDK2,SELL,SLITRK2,SLITRK3,TENM1,TRO |
| GO_SENSORY_PERCEPTION | 0.0e+00 | 0.0e+00 | 1813 | 978 | 92 | ARL6,ASIC1,ASIC3,ATP2B2,ATP8A2,AZGP1,CA6,CABP1,CACNB2,CALHM1,CCN3,CDC14A,CDH3,CHRNA10,CHRNA7,CHRNB2,CLIC5,CNGA1,CNGB1,COL4A3,CRYBB3,CRYM,DCDC2,DLL4,DRD2,FGFR1,GABRB2,GFY,GJA3,GJC3,GNAT2,GPR143,GRIN1,GRM7,GUCA1B,GUCA1C,HOXA1,HTR2A,IAPP,IRX5,KCND2,KCNQ4,LPO,MBP,MYH14,NPY1R,OAT,OLFM2,OPRD1,OPRK1,OR10K1,OR1M1,OR2A7,OR2G6,OR2L5,OR51B4,OR52E2,OR5AN1,OR7D2,OR7G2,OR8G5,OTOA,P2RX7,P2RY1,PIGR,PJVK,POU4F1,POU4F3,PRCD,PTAFR,RDH10,RDH12,RGS9,RORB,SCN3B,SCNN1D,SEMA5B,SLC17A8,SLC24A4,SLC4A10,SLC52A3,SRRM4,TAS2R4,TIMP3,TMEM100,TMEM150C,TMPRSS3,TRPA1,TRPM8,TRPV2,TUB,USH2A |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1859 | 141 | ABO,ACER2,ACER3,ACHE,ACSL6,ADA2,ADCY4,AK5,AK9,ALAS1,ALDH3B2,ALG1L2,ASGR1,AZIN2,B3GAT2,B3GNT3,B4GALT4,B4GALT5,BACE2,CALR,CARD11,CD74,CD86,CEBPA,CELF4,CHST4,CHST6,CLEC7A,CPEB3,CSGALNACT1,CSPG5,DAPK1,DDC,DDX25,DNAJC1,DPY19L2,DPY19L2P2,EIF4A2,EIF4A3,ELOVL4,EXT1,EXTL2,FA2H,FGF21,FMOD,FTO,GAD1,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,GGTLC3,GLS,GLS2,GOLGA7,GPAT4,GPC2,GPR37,GSTM3,GUCA1B,GUCA1C,GUCY1A1,GUCY1A2,GUCY1B1,HS6ST1,INHBB,ITM2C,JAK2,LARGE2,LIN28A,LPCAT2,MAGT1,MALSU1,MAN1C1,MAP6D1,METTL14,MGAT4A,MKNK1,MOCS2,MTAP,MUC20,NCK2,NEURL1,NMT2,NOA1,NOS1,NOS2,NOXRED1,OAT,OAZ2,OGA,ORMDL3,P2RX7,PANK3,PCSK5,PCYT1B,PHOSPHO1,PIWIL3,PLA2G4A,PLPP2,POMGNT2,PPM1L,PRELP,PRKD2,PRTFDC1,PTAFR,PTGIS,RBM24,RIMKLA,RIMKLB,RMND1,RPL3L,RPS6KA3,SAMD4B,SDF2,SGPP1,SLC44A3,SOX4,SPTA1,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,STT3B,TARS3,TBPL1,TLCD3B,TLR7,TPH1,TPH2,TUSC3,UGCG,UGT8,VCAN,XYLT1,ZDHHC11B,ZDHHC15,ZDHHC23 |
| GO_SECOND_MESSENGER_MEDIATED_SIGNALING | 0.0e+00 | 0.0e+00 | 1813 | 443 | 57 | ADCY4,ADCYAP1R1,ADGRB2,ADGRB3,ADGRE1,ADGRL1,ADGRL2,ADRA1A,AHR,AKAP6,ATP1B1,AVPR1A,CCR6,CCRL2,CD22,CHP2,CX3CR1,CXCR2,DRD2,FKBP1B,FPR2,GNAL,GPR143,GPR65,GRIN1,GUCY1A1,GUCY1A2,GUCY1B1,HAP1,IAPP,KSR1,KSR2,LGR5,MAFA,MC2R,MCTP2,MT1F,NCALD,NDNF,NFATC4,NMUR1,NOS1,NOS1AP,NOS2,NR5A2,P2RX7,PDE10A,PDE11A,PEX5L,PRKAR2B,PTGER4,RGN,RUNDC3A,SAMD14,SLA2,TMEM100,TNNI3 |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 0.0e+00 | 1813 | 1210 | 105 | ABCG4,ADAM23,AFF3,AKAP6,ALOX15,BTRC,CAMK2B,CBL,CCL26,CCR6,CCRL2,CD38,CD40,CD70,CD74,CD86,CDK9,CEACAM1,CEBPA,CIITA,CORO1A,CRLF1,CSF1R,CX3CR1,CXCR2,DAPK1,DOCK8,DPYSL3,DUSP1,EDA,EIF4A2,ETV3,FGG,GBP5,GHR,GLDC,GNAO1,GRB2,GREM2,HCK,HLA-DPB1,IFNLR1,IL11,IL12A,IL16,IL17RD,IL19,IL1R2,IL1RAPL1,IL23R,IL2RB,IL33,IL34,IL3RA,IL7,ILDR1,ITGAM,ITGAX,JAK2,JUN,KCNJ11,KLF5,LAMP3,MAPK11,MRC1,MTAP,NCAM1,NKX3-1,NKX6-1,NOS2,NR5A2,NRP2,OAS1,OASL,OCLN,OPRD1,PALM3,PDE1B,PELI1,POSTN,POU4F1,PSMD9,PTAFR,PTGIS,PTPRZ1,ROBO1,SAMHD1,SCRIB,SELPLG,SH2B3,SLC2A4,SLIT3,SPOCK2,STAT4,STX1A,TCF7,TIMP3,TIMP4,TNFRSF19,TNFRSF8,TNFSF15,TXK,UGCG,VAV1,WAS |
| GO_IMMUNE_EFFECTOR_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1267 | 108 | ACE,ADA2,AICDA,AOC1,ARHGAP9,AZGP1,C5,CBL,CCR6,CD1D,CD22,CD40,CD70,CD74,CD86,CEACAM1,CFHR1,CHRNB4,CLU,COLEC10,CORO1A,CR2,CRTAM,CXCR2,CYBB,CYFIP2,DYNLL1,ELMO2,EMP2,EOMES,FCN1,FFAR2,FPR2,FRMPD3,GCA,GCNT3,GOLGA7,GPRC5B,GRB2,HAVCR2,HCK,HERC5,HLX,HP,HUWE1,HVCN1,IFNLR1,IL12A,IL23R,IL33,IST1,ITGAL,ITGAM,ITGAX,KLK7,LAIR1,LILRA2,LTF,LY9,MAGT1,MGAM,MYO10,MYO1G,NCKAP1L,NECTIN2,NFASC,OAS1,OASL,OPRK1,ORMDL3,P2RX7,PIGR,PLCL2,PLPP4,POLR3A,PRKCZ,PTAFR,PTGER4,PTK2,PTPRN2,PYGL,RAB37,RAB44,RAB9B,RAET1G,RNF125,RNF216,S100A9,SAMHD1,SCIMP,SELL,SEMA7A,SERPINB9,SH2D1A,SIGLEC14,SLA2,SLAMF7,SPN,SPTAN1,SUSD4,TLR7,TMC6,TMEM30A,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 895 | 86 | AZGP1,BTN2A2,BTNL9,BTRC,C5,CARD11,CD1D,CD209,CD22,CD38,CD3D,CD40,CD74,CD86,CEACAM1,CFHR1,CLEC7A,CLU,COLEC10,CR2,CRTAM,CYFIP2,ELMO2,FCN1,FFAR2,FGG,FPR2,FYB2,GBP5,GCSAML,GPRC5B,GRB2,HAVCR2,HCK,HHLA2,HLA-DPB1,HLX,ICAM2,IL12A,IL23R,IL33,ITGAM,ITK,KLK7,LGMN,LILRA2,LTF,MAP2K6,MUC20,MYO10,MYO1G,NCKAP1L,NECTIN2,P2RX7,PAX5,PELI1,PIK3AP1,PLCL2,PLPP4,PRKCZ,PRKD2,PSMD9,PTAFR,PTK2,RAB29,RAET1G,RNF125,RPS6KA3,S100A9,SCIMP,SEMA7A,SFTPA2,SH2D1A,SLA2,SMPDL3B,SUSD4,TESPA1,THEMIS2,TLR10,TLR5,TLR7,TRAC,TXK,UBE2D1,VAV1,WAS |
| GO_PEPTIDYL_TYROSINE_MODIFICATION | 0.0e+00 | 0.0e+00 | 1813 | 372 | 51 | ACE,ADRA1A,AFAP1L2,BMP6,BMX,CADM4,CBL,CD40,CD74,CNTN1,CRLF1,CSF1R,DOK7,DYRK1B,EPHA6,EPHB2,EPHB3,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,GHR,GPRC5B,GREM1,HCK,HTR2A,IL11,IL12A,IL23R,IL7,ITK,JAK2,LMTK2,MAP2K3,MAP2K6,MATK,NCK2,NEURL1,NOX4,PRKCZ,PTK2,SEMA4D,SH2B3,SOCS4,SRCIN1,STYK1,TESK2,TPST1,TXK,ZGPAT |
| GO_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 695 | 73 | ACER2,ACVRL1,ADAM22,ALOX15,ARHGAP6,BMP6,BTN2A2,CALR,CAMSAP3,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CDH1,CDKN2A,CEACAM1,CHRD,CORO1A,CSPG5,DOCK8,DUSP1,DUSP26,EMP2,EPB41L5,EPHB3,FGG,FGL1,FOXA1,GRB2,GREM1,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,ITGA6,JAK2,JAM3,KIF26B,KNG1,LAMA4,MBP,MDGA1,MIA3,MYO10,NCK2,NCKAP1L,NDNF,PELI1,PLA2G2D,PODXL,POSTN,PRKCZ,PRKD2,PTAFR,PTK2,RUNX3,SEMA4D,SH2B3,SPN,SPOCK2,SPTA1,TESC,TESPA1,VAV1,ZNF703 |
| GO_REGULATION_OF_GROWTH | 0.0e+00 | 0.0e+00 | 1813 | 680 | 72 | ACVRL1,AKAP6,ARHGAP4,ATP8A2,AVPR1A,BCL11A,BCL2L11,CACNA2D2,CACNG7,CCN3,CD38,CDKL3,CDKN2A,CEACAM1,CLSTN3,CSPG5,DACT3,DCC,DMAP1,DRAXIN,DRD2,EAF2,FGFR1,FGFR2,FGFR3,FTO,GDF9,GHR,GLI1,GNG4,GPAT4,GREM1,HEY2,HLX,HNF4A,HOXB13,IGFBP2,IGSF11,IL7,ISLR2,IST1,KCNK2,LGMN,MAPK11,MT1F,MYL2,NEDD4L,NKD1,NKX6-1,NPY1R,NTN1,OLFM1,PLS1,PRAME,PTK2,RND2,RPS6KA3,S100A9,SEMA4D,SEMA7A,SGK2,SHTN1,SLC6A4,SLIT3,SOCS4,STK3,SYT2,TFCP2L1,TLL2,TMPRSS4,TRPV2,ZFYVE27 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1813 | 1782 | 135 | ACTN2,ACTR3C,ADD2,ALOX15,ANKS4B,ANXA9,ARHGAP40,ARHGAP6,ARL6,ASIC1,BCL2L11,BCL9,BIK,CALHM1,CALR,CAMSAP3,CCL26,CD3D,CD40,CD74,CELF2,CELF4,CELF5,CHRNB2,CHRNB4,CLEC7A,CLU,CNGB1,CNIH2,CORO1A,CPT1A,CRACD,DISP1,DNAAF3,DNAH7,DNAI1,DPYSL3,ESAM,F5,FBXL7,FCHO1,FCHSD1,FGG,FMOD,FSD1,GBP5,GLRA3,GLS,GRB2,GREM1,GRIN1,HBE1,HCK,HEY2,IAPP,IKZF5,IL2RB,ILDR1,JAK2,JAM3,KCNC1,KCNC3,KCND1,KCND2,KCNJ12,KCNV1,KCTD15,KCTD17,KCTD2,LCMT1,LDLRAD4,LRRC8C,LUC7L,MAGI2,MAPK15,MAPK8IP2,MAPRE3,MAT1A,NAP1L6P,NAPG,NCK2,NCKAP1L,OAT,OCLN,OPRD1,P2RX7,PADI4,PCDHGA3,PFDN6,PPP6C,PRKCZ,PRMT8,PRND,PSMD9,PTGER4,PTK2,REPS2,RIC3,RPL3L,RYR1,RYR3,SAMHD1,SCFD1,SCIN,SCUBE1,SEC22B,SEPTIN4,SHKBP1,SLC6A1,SLC6A4,SNX2,SPTA1,SPTAN1,SPTB,SRPK2,STX1A,TCF7,TCF7L1,TENM1,TESPA1,TLE3,TNFAIP1,TPPP3,TRIM9,TRPA1,TSPAN33,TSPY26P,TUBB4A,UBN1,UPK1A,VWA2,WAS,WASF3,WDCP,ZNHIT6 |
| GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 378 | 51 | AMIGO1,ATOH1,ATP8A2,BMP6,BRINP1,BRINP2,C21orf91,CACNG7,CAMK1D,CAMK2B,CDKL3,CHODL,CNTN1,CPEB3,DPYSL3,FBXO31,FGFR1,FKBP1B,FOXA1,GDF6,GPC2,GPRC5B,HEYL,IL1RAPL1,ISLR2,IST1,ITGA6,KALRN,KDM1A,LIN28A,LLPH,MAGI2,MAP6,MMD,NDNF,NEDD4L,NEURL1,NGFR,NKX6-1,NTN1,RARB,RND2,ROBO1,S100A9,SEMA4D,SEMA7A,SHTN1,SYT2,TMEM30A,TRPV2,ZFYVE27 |
| GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 302 | 45 | ADGRB3,AMIGO1,ARHGAP4,ARHGAP44,CALR,CAMK2B,CDH2,CDKL3,CHODL,CHRNB2,CSPG5,DCC,DRAXIN,EPHB2,EPHB3,FBXO31,FGG,GRIN1,IL1RAPL1,ISLR2,IST1,KALRN,KIF13B,KNDC1,LINGO1,LRRC4C,LZTS1,MAP6,NEDD4L,NFATC4,NGFR,NKX6-1,NTN1,OLFM1,POSTN,PTK2,RND2,ROBO1,SEMA4D,SEMA7A,SHTN1,SRCIN1,TRPV2,XK,ZFYVE27 |
| GO_TUBE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 928 | 87 | ACVRL1,ADGRB2,ADGRB3,AHI1,ANGPTL6,ANXA9,BCL2L11,BTRC,C5,CASR,CCN3,CD34,CD40,CDH2,CEACAM1,CHRNA7,COL4A3,COMP,CSF1R,CX3CR1,CXCR2,CYBB,DLL4,EDA,EMP2,EOMES,EPB41L5,EPHB2,EPHB3,FGF18,FGFR1,FGFR2,FLT4,FOXA1,GLI1,GPR4,GREB1L,GREM1,HESX1,HEY2,HLX,HOXA1,HOXB13,HS6ST1,ISM1,ITGAX,JAM3,JUN,KIF26B,KLF5,LGR5,LRP6,MIA3,MSX2,MYO18B,NDNF,NFATC4,NGFR,NKX2-1,NKX3-1,NOTCH3,NOX5,NRP2,NTN1,PLCD1,PLXDC1,PODXL,PPP1R16B,PRKD2,PTGIS,PTK2,RDH10,ROBO1,SCG2,SCRIB,SOSTDC1,SOX4,SPINT1,SRPK2,STAB1,STK3,TCF7,TMEM100,TNNI3,TSPAN12,UNC5B,VASH2 |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1813 | 1364 | 112 | ABHD6,ACTN2,ADCY4,ADCYAP1R1,ADGRB2,ADGRB3,ADGRE1,ADGRF2,ADGRL1,ADGRL2,ADRA1A,ARHGEF3,ATRNL1,AVPR1A,C5,CASR,CCL26,CCR6,CCRL2,CHRM4,CNGA1,CNGB1,CX3CR1,CXCR2,DRD2,DRD4,FCN1,FFAR2,FGD2,FPR2,FZD9,GABRA1,GABRA6,GABRB2,GLRA3,GNAL,GNAO1,GNAT2,GNAZ,GNB1L,GNG4,GPBAR1,GPR135,GPR143,GPR162,GPR37,GPR37L1,GPR4,GPR65,GPRC5B,GRM7,GUCA1B,GUCA1C,HTR2A,IAPP,JAK2,KALRN,KCNK2,KNG1,LGR5,LPAR5,LTB4R2,MC2R,MCF2L,NMT2,NMUR1,NOS1,NPFFR1,NPFFR2,NPY1R,OPRD1,OPRK1,OR10K1,OR1M1,OR2A7,OR2G6,OR2L5,OR51B4,OR52E2,OR5AN1,OR7D2,OR7G2,OR8G5,OXGR1,P2RY1,P2RY8,PDE10A,PDE11A,PDE1B,PDE4C,PDGFRL,PIK3R5,PLCL2,PREX2,PTAFR,PTGER4,RGS10,RGS7,RGS9,RORB,S1PR3,S1PR5,SORCS1,SPNS2,SSTR2,SYP,TAS2R4,TENM1,TUB,VAV1,VIPR2,XPR1 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1870 | 139 | ACTN2,ACVR2A,ACVRL1,AFAP1L2,AHI1,AHR,AICDA,ALX4,ARID3B,ARID3C,ATOH1,BARX2,BCL9,BMP6,BORCS8-MEF2B,BTRC,C1orf61,CAMK4,CD38,CD3D,CD40,CD74,CD86,CDH1,CDK9,CEBPA,CELF4,CHP2,CIITA,CPEB3,CREB3L3,DLX4,DMRT1,DRD2,DYRK1B,EAF2,EBF2,EGR2,ELOF1,EOMES,ESRRB,FGFR2,FGFR4,FOXA1,FOXD2,FTO,GCM1,GDF6,GLI1,GLIS3,GREM1,GRHL1,GRIN1,GTF2A1,GUCA1B,GUCA1C,HEY2,HEYL,HIVEP3,HLTF,HNF4A,HOXA1,HTR2A,IKZF5,IL11,IL33,ITGA6,JUN,KDM1A,KLF5,LHX4,LHX6,LIN28A,LMX1B,LRP6,MAFA,MAP2K3,MAPK15,MAPRE3,MED12L,MED21,MEOX1,METTL14,MRTFA,MYCL,MYRF,NCK2,NFATC4,NFE2L3,NGFR,NKX2-1,NKX3-1,NKX6-1,NOS1,NOS2,NOTCH3,NOX4,NPAS1,NPAS3,NR2F1,NR5A2,NR6A1,P2RX7,P2RY1,PAX5,PAX9,PITX2,POU2F3,POU4F1,POU4F3,PRKCG,PRKD2,PSMD9,RARB,RASL11A,RBM20,RBM24,RGMA,RORB,RPS6KA3,RUNX3,SALL2,SLC40A1,SMARCA1,SNAI1,SOX4,SOX6,SPDEF,STAT4,STPG4,TACC1,TAF1L,TBPL1,TESC,TIGAR,TXK,VGLL2,WAS,ZBTB7C |
| GO_MUSCLE_STRUCTURE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 673 | 71 | ACHE,ACTN2,ADGRB3,ADRA1A,AKAP6,AKIRIN1,ALX4,AVPR1A,BARX2,BCL9,BOC,BORCS8-MEF2B,CACNA2D2,CALR,CCN3,CDH15,CDH2,CDK9,CFL2,CHODL,COL19A1,COMP,CYP26B1,DISP1,DLL4,DYRK1B,EGR2,EOMES,FBXO40,FGFR1,FGFR2,GLI1,GREM1,HEY2,HEYL,HIVEP3,HLX,IFT20,KCNK2,KDM1A,KLF5,LUC7L,MAPK11,MRTFA,MYH14,MYH15,MYL2,MYO18B,NEURL1,NFATC4,NKD1,NOS1,NOX4,OLFM2,PAX5,PDLIM3,POU4F1,PRDM6,RARB,RBM24,RBM38,RYR1,SGCZ,SOSTDC1,SOX6,SYPL2,TLL2,TNNI3,TNNT2,VGLL2,XK |
| GO_POTASSIUM_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 245 | 40 | ABCC8,ACTN2,AKAP6,AMIGO1,ATP1A3,ATP1B1,ATP1B2,DRD2,HCN2,HCN4,HTR2A,KCNC1,KCNC3,KCND1,KCND2,KCNE5,KCNH2,KCNH4,KCNH8,KCNIP4,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK2,KCNK5,KCNK9,KCNMB1,KCNN1,KCNN2,KCNN3,KCNQ4,KCNT2,KCNV1,NEDD4L,NOS1,NOS1AP,SLC12A8,SLC24A4 |
| GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 234 | 39 | ADGRB2,ADGRB3,ADGRL1,AMIGO1,ARHGAP44,CAMK2B,CAMKV,CBLN2,CDH2,CHRNB2,CLSTN3,CRIPT,DRD2,EPHB2,EPHB3,FZD9,GRIN1,IGSF9,IL1RAPL1,KALRN,LRFN1,LRFN5,MDGA1,MESD,NEURL1,NFATC4,NRP2,NRXN1,NTN1,NTNG2,PTK2,RAB17,SEMA4D,SLC17A8,SLIT1,SLITRK2,SLITRK3,SRCIN1,SYBU |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1813 | 725 | 74 | ADAMTS3,AFAP1L2,AHI1,ATP6V0B,ATP6V1C2,CADM4,CBL,CDH3,CEACAM1,CNKSR1,COL4A3,CSF1R,CYBB,CYFIP2,DOK5,EFNA2,ELMO2,ENHO,EPHA6,EPHB2,EPHB3,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,GAREM1,GFRA2,GHR,GRB2,GREM1,GRIN1,HAP1,HCK,IFT20,IGFBP2,JAK2,KALRN,LGMN,LMTK2,MAPK11,MATK,MUC20,NCK2,NCKAP1L,NEURL1,NFATC4,NGFR,NKX3-1,NRG2,NRP2,PDGFRL,PIGR,PLAT,PRKCZ,PRKD2,PTK2,PTPN3,REPS2,ROBO1,SH2B3,SH3TC2,SHISA2,SHKBP1,SLC30A10,SOCS4,STAM2,SULF2,VAV1,VWA2,ZFYVE27,ZGPAT |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1813 | 973 | 89 | ADCYAP1R1,AHR,AKAP6,AOC1,ATP1A3,AVPR1A,BCL2L11,BMP6,BTRC,CALR,CASR,CBL,CD38,CD40,CD83,CDH1,CEBPA,CHRM4,CHRNB2,CLU,CPT1A,CYBB,CYP1A1,CYP1A2,DHH,DRD2,DRD4,DUSP1,EIF4A3,ESRRB,FKBP1B,FOXA1,GABRA1,GABRB2,GLDC,GNAL,GNAO1,GRIN1,HBE1,HCN2,HCN4,HEYL,HNF4A,HOXB13,HSD11B2,HTR2A,HTR3A,HTR3B,IGFBP2,ITGA6,JAK2,JUN,KCNJ11,KCNMB1,KDM1A,KLF5,LRP6,MSX2,NFATC4,NKX3-1,NOX4,NR2C1,NR2F1,NR5A2,NR6A1,P2RX7,P2RY1,PELI1,POSTN,POU4F1,PRKAR2B,PRKCG,PTAFR,RARB,RGS9,RORB,RYR1,RYR3,SELL,SLC5A5,SLC6A1,SLC6A4,SLIT3,SP5,SSTR2,TAT,TPH2,TRPA1,ZNF703 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 777 | 77 | ACVR1C,AICDA,ANXA9,BCL2L11,BMP6,BTRC,CALR,CARD11,CD1D,CD209,CD74,CDK9,CEACAM1,CLEC7A,CRTAM,CSF1R,DRD2,FCN1,FFAR2,FGG,FPR2,GBP5,HAVCR2,HCK,HERC5,ICAM2,IFNLR1,IL12A,IL23R,INHBB,ITGAM,JAK2,JUN,KLK7,LAMP3,LGMN,LILRA2,LTF,MAP2K6,MUC20,NECTIN2,NOS2,NOX5,NR5A2,OAS1,OASL,P2RX7,P2RY1,PAEP,PELI1,PIK3AP1,POU2F3,PSMD9,PTAFR,RAET1G,RNF125,RNF216,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SERPINB9,SFTPA2,SH2D1A,SIGLEC11,SMPDL3B,SPINK13,SRPK2,TLR10,TLR5,TLR7,TMPRSS2,TRAFD1,TXK,UBE2D1,VAV1 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1047 | 93 | ABCA5,ACVR1C,ACVRL1,ADGRB2,ADGRB3,AKIRIN1,ANXA9,ARHGAP4,BCL11A,BMERB1,BRINP1,C1QL4,CALR,CCN3,CD38,CD74,CDH3,CDKL3,CEACAM1,CEND1,CHRD,COL4A3,CRMP1,CX3CR1,DACT3,DCC,DISP3,DLL4,DPYSL3,DRAXIN,EAF2,EPHB2,ESRRB,FGFR3,FOXA1,GPR37L1,GPR4,GREM1,HEY2,HLX,IAPP,ISM1,ITM2C,KCNK2,LDLRAD4,LGMN,LIN28A,LINGO1,LTF,LUC7L,MAPK11,MARCHF5,MSX2,MYLIP,NFATC4,NGFR,NKD1,NKX2-1,NKX3-1,NKX6-1,NOTCH3,NR2F1,NTN1,PAEP,POSTN,PRAME,PRDM6,PTK2,RAB29,RARB,RGMA,RGN,ROBO1,RORB,RTN4RL2,RUNX3,S1PR3,SEMA4D,SEMA7A,SLC30A10,SLC6A4,SLIT1,SNAI1,SOSTDC1,SOX6,SPDEF,STAB1,STK3,TLCD3B,TLL2,TMEM176B,USH2A,ZBTB46 |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 562 | 63 | AKAP6,AMIGO1,ATOH1,ATP8A2,BMP6,BRINP1,BRINP2,C21orf91,CACNG7,CALR,CAMK1D,CAMK2B,CDKL3,CHODL,CLEC7A,CNTN1,CPEB3,CSPG5,CX3CR1,DPYSL3,DRD2,EPHB2,FBXO31,FGFR1,FGG,FKBP1B,FOXA1,GDF6,GPC2,GPRC5B,HAP1,HEYL,IL1RAPL1,IL34,ISLR2,IST1,ITGA6,KALRN,KDM1A,LIN28A,LLPH,MAGI2,MAP6,MMD,NDNF,NEDD4L,NEURL1,NGFR,NKX6-1,NTN1,PTPRZ1,RARB,RND2,ROBO1,S100A9,SEMA4D,SEMA7A,SHTN1,SPINT1,SYT2,TMEM30A,TRPV2,ZFYVE27 |
| GO_CYTOKINE_PRODUCTION | 0.0e+00 | 0.0e+00 | 1813 | 808 | 78 | ADAMTS3,AFAP1L2,BTN2A2,C5,CARD11,CD34,CD40,CD6,CD74,CD83,CD86,CDH3,CEACAM1,CHRNA7,CLEC7A,CLU,CRTAM,CSF1R,CX3CR1,CYBB,DRD2,DTX4,EOMES,FCN1,FFAR2,FGFR1,FLT4,GBP5,GPRC5B,HAVCR2,HERC5,HHLA2,HLA-DPB1,IL12A,IL1R2,IL23R,IL33,IL7,INHBB,ITK,JAK2,LILRA2,LTF,LY9,MAP2K3,MAPK11,MBP,NCKAP1L,NDRG2,NFATC4,NOS2,NOX5,P2RX7,PAEP,PCSK5,PELI1,POLR3A,POSTN,PRKCZ,PRKD2,PTAFR,PTGER4,RAET1G,RNF125,RNF216,S100A9,S1PR3,SCAMP5,SCIMP,SEMA7A,SERPINB7,SPN,SULF2,TLR10,TLR5,TLR7,TNFRSF8,TXK |
| GO_DEVELOPMENTAL_MATURATION | 0.0e+00 | 0.0e+00 | 1813 | 280 | 42 | ACVRL1,ADGRB3,ADGRL1,B4GALT5,BCL11A,CAMK2B,CCR6,CDH3,CDK5R2,CEBPA,CEND1,CLEC7A,CX3CR1,FGFR1,FGFR3,FGG,FOXA1,GPAT4,GREM1,GRIN1,HOXB13,IRX5,KDM1A,L3MBTL3,LHX6,LTF,MSX2,NEURL1,NFASC,NFATC4,NKX6-1,NRXN1,PAEP,PHOSPHO1,RYR1,SEMA4D,SRRM4,SYBU,SYP,TFCP2L1,XYLT1,ZDHHC15 |
| GO_MEMBRANE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 875 | 82 | ABCB1,ABCC1,ALOX15,ANO3,ANO9,ANXA9,ARL6,ATP1B1,ATP8A2,AZIN2,BCL2L11,CALR,CBL,CD3D,CDH2,CLU,CNEP1R1,CNIH2,CORO1A,CPLX1,CRB1,CRIPT,DOC2B,EMP2,EPHB2,F5,FA2H,FCHO1,FCHSD1,FZD9,GCA,GRB2,GRIK5,GULP1,IL1RAPL1,ITGAM,IZUMO1,LPCAT2,MAGI2,MAPK15,MBP,MESD,MFN1,MIA3,MYRF,NAPG,NCKAP1L,NECTIN2,NFASC,NOX5,NRXN1,NRXN2,P2RX7,PARP11,PPP6C,REEP1,REPS2,SCFD1,SEC22B,SGCZ,SH3TC2,SLC2A4,SLC66A2,SPTA1,STAM2,STX11,STX12,STX1A,STX6,SYP,SYPL2,SYT2,TBC1D1,THEM4,TMEFF2,TMEM30A,TOR1B,TRIM9,TRIP10,UGCG,XKR4,XKR5 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1813 | 1779 | 132 | A2ML1,ACE,ACER2,ACVR1C,ADAM11,ADAM22,ADAM23,ADAM28,ADAMTS14,ADAMTS17,ADAMTS19,ADAMTS20,ADAMTS3,AMN1,ANXA9,ASRGL1,ATG4A,BACE2,BCL2L11,BTRC,C5,CAPN14,CASP14,CBL,CEBPA,CLEC16A,CLEC7A,CLU,COL4A3,COMP,CORIN,CPA4,CPM,CPVL,CPZ,CST7,CTRC,CYFIP2,DAPK1,DHH,DNAJC1,DNAJC18,FBXL7,FBXO3,FBXO31,FBXO44,FGFR4,FGG,GGTLC3,GRIN1,HP,HUWE1,IL1R2,IL33,IST1,ITIH5,JAK2,KCTD17,KCTD2,KLK1,KLK10,KLK11,KLK7,KLKB1,KNG1,LAMP3,LGMN,LTF,MBP,MINDY3,MMP13,MMP16,MYLIP,MYRF,NCCRP1,NEDD4L,NFRKB,NGFR,NKX3-1,OTUB2,OTUD3,OVCH2,P2RX7,PCSK2,PCSK5,PELI1,PLAT,PRKCG,PSMD9,PTK2,PTPN3,RGN,RHBDL3,RNF125,RNF216,RNF43,ROBO1,RPS6KA3,S100A9,SERPINB7,SERPINB9,SGTB,SH3RF2,SIRT4,SOCS4,SPINK13,SPINT1,SPOCK2,SPOCK3,SPSB4,STAM2,STT3B,TIMP3,TIMP4,TLL2,TMPRSS15,TMPRSS2,TMPRSS3,TMPRSS4,TNFAIP1,TNFSF10,TNFSF15,TRIM9,UBA3,UBAP1,UBE2D1,UBE2W,UBE3D,UBE4A,USP35,USP43,VASH2 |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 1335 | 108 | ACTN2,ACTR3C,ADD2,ALOX15,APC2,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGEF10,ATP8A2,BMERB1,CALR,CAMSAP3,CAPN6,CCL26,CDC14A,CEP19,CFL2,CLMN,CNN3,CORO1A,CRACD,CRIPT,CRMP1,CSF1R,CSPG5,CSRP2,DNAAF3,DNAH7,DNAI1,DPYSL3,ELMO2,EML1,EML4,EMP2,ENAH,EPB41L5,ESAM,FCHSD1,FGD2,FGD5,FSCN3,FSD1,GPR65,GRB2,HCK,HOOK1,HYDIN,IQCJ-SCHIP1,JAK2,JAM3,JHY,KIAA1614,KRT6B,LRGUK,MAP1S,MAP6,MAP6D1,MAP7,MAPK15,MAPRE3,MARK1,MAST1,MRTFA,MYH14,MYL2,NCK2,NCKAP1L,NECTIN2,NES,NEURL1,NOS1AP,NOX4,P2RX7,PARD6G,PDLIM3,PDZD8,PLEKHH2,PLS1,PRKCZ,PTGER4,PTK2,RHOV,RND2,S100A9,SAMD14,SCIN,SHTN1,SPECC1,SPTA1,SPTAN1,SPTB,STMND1,TACC1,TENM1,TESK2,TMEFF2,TNFAIP1,TNNT2,TPPP3,TRIP10,TUBA3C,TUBB2A,TUBB4A,UGT8,WAS,WASF3 |
| GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 334 | 46 | AKAP6,ANXA9,ASIC1,ATP1B1,ATP2A3,ATP2B2,CACHD1,CACNA1G,CACNA1I,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CALHM1,CHRNA10,CHRNA7,CLCA3P,CORO1A,DRD2,DRD4,FAM155A,FGF14,FKBP1B,GEM,GRIN1,HAP1,HTR2A,IL1RAPL1,MRLN,NOS1,NOS1AP,P2RX7,PKD1L2,PLCD1,PLCH1,PLCL2,RGN,RGS9,RYR1,RYR3,SLC24A4,SLN,TRPA1,TRPM8,TRPV2,TRPV3 |
| GO_CARDIAC_CONDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 146 | 30 | ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,CACNA1G,CACNA2D1,CACNA2D2,CACNB2,CACNG7,CORIN,DSC2,FKBP1B,FXYD7,HCN4,KCND1,KCND2,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNJ12,KCNJ5,KCNN2,NOS1,RYR1,RYR3,SCN3B,SCN4B,SCN5A |
| GO_INFLAMMATORY_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 765 | 75 | ABCC1,ACER3,AFAP1L2,ALOX15,BACE2,BMP6,C5,CAMK1D,CAMK4,CCL26,CCN3,CCR6,CCRL2,CD40,CD6,CEBPA,CHST4,CIITA,CLEC7A,CLU,CREB3L3,CSF1R,CST7,CXCR2,CYBB,CYP26B1,FFAR2,FPR2,GBP5,GPRC5B,HAVCR2,HCK,HP,IL1R2,IL23R,IL33,IL34,ITGAL,ITGAM,JAK2,JAM3,JUN,KLKB1,KNG1,LRFN5,LTB4R2,MAP2K3,NFATC4,NFRKB,NOS2,NOX4,P2RX7,PIK3AP1,PLA2G2D,PLP1,PRKCZ,PSTPIP1,PTAFR,PTGER4,PTGIS,S100A9,S1PR3,SAA4,SCG2,SCUBE1,SEMA7A,SMPDL3B,STAB1,TAFA3,THEMIS2,TLR10,TLR5,TLR7,TPST1,TSPAN2 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1710 | 128 | ACTN2,ACVR2A,ACVRL1,AFAP1L2,AHI1,AHR,AICDA,ALX4,ARID3B,ARID3C,ATOH1,BARX2,BCL9,BMP6,BORCS8-MEF2B,BTRC,C1orf61,CAMK4,CD38,CD3D,CD40,CD74,CD86,CDH1,CDK9,CEBPA,CELF4,CHP2,CIITA,CPEB3,CREB3L3,DLX4,DMRT1,DRD2,DYRK1B,EAF2,EBF2,EGR2,ELOF1,EOMES,ESRRB,FGFR2,FOXA1,FOXD2,FTO,GCM1,GDF6,GLI1,GLIS3,GREM1,GRHL1,GRIN1,GTF2A1,HEY2,HEYL,HIVEP3,HLTF,HNF4A,HOXA1,IKZF5,IL11,IL33,ITGA6,JUN,KDM1A,KLF5,LHX4,LHX6,LIN28A,LMX1B,LRP6,MAFA,MAP2K3,MAPRE3,MED12L,MED21,MEOX1,METTL14,MRTFA,MYCL,MYRF,NCK2,NFATC4,NFE2L3,NGFR,NKX2-1,NKX3-1,NKX6-1,NOS1,NOTCH3,NPAS1,NPAS3,NR2F1,NR5A2,NR6A1,P2RY1,PAX5,PAX9,PITX2,POU2F3,POU4F1,POU4F3,PRKD2,PSMD9,RARB,RASL11A,RBM20,RBM24,RGMA,RORB,RPS6KA3,RUNX3,SALL2,SLC40A1,SMARCA1,SNAI1,SOX4,SOX6,SPDEF,STAT4,TACC1,TAF1L,TBPL1,TESC,TXK,VGLL2,WAS,ZBTB7C |
| GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1813 | 548 | 61 | ADRA1A,ALOX15,ANKRD6,C5,CASR,CCL26,CD40,CD74,CDH2,CHRNA7,CSF1R,DOK5,DRD2,DRD4,DUSP9,FGD2,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,GDF6,GHR,GPR37,GPR37L1,HAVCR2,HTR2A,IAPP,IL11,JAK2,JUN,KSR1,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPK8IP2,MUC20,NOX4,P2RX7,P2RY1,PIK3R5,PRKCZ,PRKD2,RB1CC1,ROBO1,SCIMP,SEMA7A,SH3RF2,SLC30A10,STK3,TENM1,TNFRSF19 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 643 | 67 | ABCC1,AKIRIN1,BMP6,BTRC,CALR,CAMK1D,CARD11,CASR,CCL26,CCR6,CD1D,CD209,CD6,CD74,CEBPA,CLEC7A,CREB3L3,CRTAM,CXCR2,DAPK2,FCN1,FFAR2,FGF18,FGFR1,FGG,FKBP1B,FPR2,GBP5,GPRC5B,HAVCR2,HCK,ICAM2,IL12A,IL16,IL33,ITGAM,JAK2,KLK7,KLKB1,LGMN,LILRA2,LTF,MAP2K6,MUC20,NCKAP1L,NECTIN2,PELI1,PIK3AP1,PRKD2,PSMD9,PTGER4,RAET1G,RNF125,RPS6KA3,S100A9,SCG2,SCIMP,SFTPA2,SH2D1A,SMPDL3B,TAFA3,TLR10,TLR5,TLR7,TXK,UBE2D1,VAV1 |
| GO_ORGANIC_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 492 | 57 | ABCB1,ABCC1,ACE,ANO3,ANO9,ASIC3,ATP8A2,AVPR1A,CA6,CALHM1,CASR,CEACAM1,CPLX1,CPT1A,CYB5R1,CYB5R4,DRD2,DRD4,GLS,GLS2,GRM7,HBA1,LRRC8C,LRRC8E,MAP2K6,NOS2,P2RX7,PLA2G2D,PLA2G4A,RTBDN,SLC13A3,SLC16A10,SLC16A2,SLC16A5,SLC17A8,SLC1A4,SLC1A6,SLC22A11,SLC27A6,SLC36A2,SLC36A3,SLC4A10,SLC4A5,SLC4A8,SLC52A3,SLC66A2,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,SLCO2B1,STX1A,TMEM30A,XK,XKR4,XKR5 |
| GO_REGULATION_OF_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 411 | 51 | ALOX15,BMP6,BTN2A2,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CDH1,CEACAM1,CORO1A,DOCK8,EPB41L5,EPHB3,FGG,FGL1,FOXA1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,ITGA6,JAK2,KIF26B,MBP,MDGA1,MIA3,MYO10,NCK2,NCKAP1L,PELI1,PLA2G2D,PODXL,PRKCZ,PTAFR,PTK2,RUNX3,SH2B3,SPN,SPTA1,TESPA1,VAV1,ZNF703 |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1813 | 1174 | 98 | A2ML1,ACE,ACTN2,ANO9,ANXA9,BTRC,C5,CABP1,CAMSAP3,CBL,CDKN2A,CEACAM1,CEBPA,CFHR1,CNN3,COL4A3,CRMP1,CST7,CTTNBP2NL,DRD2,DRD4,DUSP1,DUSP26,DUSP9,EIF4A2,EIF4A3,ELFN1,ENHO,EOMES,EPB41L5,EPHB2,ETFBKMT,FKBP1B,GEM,GPATCH2,GSKIP,HAVCR2,HEY2,HEYL,HP,IL7,ITIH5,JAK2,JUN,KCNE5,KDM1A,KNG1,LAMP3,LMTK2,LMTK3,LRP6,LTB4R2,LTF,MAPK8IP1,MRLN,MSX2,NCKAP1L,NEDD4L,NES,NFATC4,NGFR,NKX3-1,NOS1,OAZ2,P2RY1,PELI1,PLIN5,PPP1R14C,PPP1R1C,PRKAR2B,PRKCZ,PTGIS,PTPRN2,RGN,RIMBP2,RPS6KA3,SCRIB,SEMA4D,SERPINB7,SERPINB9,SFI1,SH2B3,SH3RF2,SLN,SOCS4,SPINK13,SPINT1,SPOCK2,SPOCK3,SRCIN1,SYMPK,TESC,TIMP3,TIMP4,TNNI3,TNNT2,ZGPAT,ZNF431 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 0.0e+00 | 1813 | 1107 | 94 | ABHD6,ACE,ACVR1C,ACVRL1,AKIRIN1,ARHGAP4,BMERB1,C5,CADM4,CALR,CAMK1D,CAMK2B,CAMSAP3,CCL26,CCN3,CCR6,CD40,CD74,CDH1,CEACAM1,CHRD,CLEC7A,CNIH2,CORO1A,CSF1R,CX3CR1,CXCR2,DAPK2,DLL4,DOCK8,DPYSL3,DRD2,DSC2,DUSP1,EMP2,EPB41L5,FBXO31,FGF18,FGFR1,FLT4,FPR2,GCSAML,GREM1,HAP1,HCN4,IL12A,IL33,ITGA6,ITGAX,JAK2,JAM3,JUN,LAMA4,LDLRAD4,LGMN,LRRC15,MAGI2,MAP2K3,MAPK15,MIA3,MPP1,NCKAP1L,NKD1,NKX2-1,NKX6-1,NOS1AP,NOX4,NRG2,NRP2,NTN1,PODXL,POSTN,PRKD2,PTAFR,PTGER4,PTK2,RGN,RND2,ROBO1,SCN5A,SEMA4D,SEMA7A,SH3RF2,SHTN1,SNAI1,SPN,SPOCK2,SPOCK3,SRCIN1,SRGAP3,STK26,TMEFF2,WAS,ZNF703 |
| GO_DENDRITE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 244 | 38 | ADGRB3,ARHGAP44,BCL11A,C21orf91,CAMK1D,CAMK2B,CDKL3,CHRNA7,CHRNB2,CPEB3,DCC,DCDC2,DCLK1,EPHB2,EPHB3,FBXO31,GRIN1,IGSF9,IL1RAPL1,KALRN,KNDC1,LLPH,LZTS1,MAP1S,MAP6,MAPK8IP2,MARK1,NCK2,NEDD4L,NEURL1,NFATC4,NTN1,NTN5,PREX2,RAB17,SEMA4D,SRCIN1,TMEFF2 |
| GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 233 | 37 | ARHGAP4,BCL11A,CACNG7,CDKL3,CYFIP2,DCC,DCLK1,DRAXIN,EPB41L5,FGFR2,ISLR2,IST1,KIF26B,LLPH,LRP6,MAGI2,NEDD4L,NKD1,NKX6-1,NRN1L,NRP2,NTN1,OLFM1,POSTN,POU4F3,PRKCZ,RDH10,RND2,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SYT2,TRPV2,ZFYVE27 |
| GO_EPITHELIAL_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 774 | 74 | ACVRL1,AHI1,ANXA9,ATOH1,BMP6,CAMSAP3,CASP14,CD34,CDH2,CDH3,CEACAM1,CNFN,CNN3,CPT1A,CYP1A1,CYP26B1,DHRS9,DMRT1,DSC2,DSC3,DSG3,EPB41L5,FA2H,FGFR1,FGFR2,FOXA1,GLI1,GPAT4,GPR4,GREM1,GRHL1,GSTM3,HEY2,HNF4A,HOXB13,HYDIN,JUN,KAZN,KLF5,KRT6B,KRT78,KRTAP9-6,MAGI2,MSX2,MYCL,NKX2-1,NKX6-1,NR5A2,NUP210L,PITX2,PODXL,POU4F3,PPP1R16B,RARB,S1PR3,SCEL,SCRIB,SCUBE1,SGPP1,SLC4A5,SOX4,SPDEF,SULT2B1,TDRD7,TFCP2L1,TGM5,TIGAR,TJP1,TMEM100,UGCG,UPK1A,USH2A,VSIG1,ZNF703 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1813 | 1135 | 95 | ABCC1,ACTN2,ACVR1C,ADCY4,AHR,AKAP6,AMIGO1,AOC1,ASIC1,ATP1A3,ATP6V0B,ATP6V1C2,BCL11A,BCL2L11,CACNA2D1,CASR,CD40,CDH1,CEACAM1,CHRM4,CHRNA7,CHRNB2,CPEB3,CYBB,DDC,DNAJC18,DRD2,DRD4,DUSP1,EGR2,ENHO,FBXO44,FGF21,FPR2,GABRA1,GABRB2,GHR,GLDC,GLRA3,GNAL,GNAO1,GRB2,GRIN1,GSTM3,GUCY1B1,HCN2,HCN4,HSD11B2,HTR2A,HTR3A,HTR3B,INHBB,JAK2,JUN,KCNC1,KCNJ11,KDM1A,KLF5,LGMN,LRP6,MIA3,MMP13,NCCRP1,NEURL1,NGFR,NKX6-1,NOX4,P2RX7,P2RY1,PDE1B,PELI1,PRKAR2B,PRKCG,PRKCZ,PTAFR,PTK2,RGS10,RGS9,RYR1,RYR3,SELL,SGTB,SLC18A2,SLC2A4,SLC30A10,SLC5A5,SLC6A1,SLC6A4,STAT4,STT3B,SYAP1,TIMP4,TNFSF10,UBE4A,VWA2 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE | 0.0e+00 | 0.0e+00 | 1813 | 367 | 47 | ACTN2,ACTR3C,ADD2,ALOX15,ALS2,ARHGAP4,ARHGAP40,CCL26,CDKL3,CFL2,CORO1A,CRACD,DCC,DRAXIN,ESAM,FCHSD1,GRB2,HCK,ISLR2,IST1,KDM1A,NCK2,NCKAP1L,NKX6-1,NTN1,OLFM1,P2RX7,PLEKHH2,PLS1,RAB3B,RB1CC1,RND2,SCIN,SEMA4D,SEMA7A,SHTN1,SLC12A8,SPTA1,SPTAN1,SPTB,TENM1,TMEM123,TRPV2,VAV1,WAS,XK,ZFYVE27 |
| GO_REGULATION_OF_PEPTIDE_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 511 | 57 | ABCC8,ACHE,ACVR1C,BMP6,BMP8A,BTN2A2,C5,CACNA2D2,CASR,CCN3,CD22,CD34,CD38,CD40,CD74,CPT1A,CRTAM,CSF1R,DISP1,DNAJC1,DOC2B,DRD2,DRD4,ENHO,FCN1,FFAR2,FGG,FKBP1B,HAVCR2,HNF4A,IL1R2,IL33,ILDR1,INHBB,JAK2,KALRN,KCNJ11,LILRA2,MAPK11,MBP,NKX6-1,NOS2,P2RX7,PAEP,POSTN,PRKCZ,PSMD9,PTGER4,SCAMP5,SIRT4,SOX4,SRCIN1,STX1A,SYBU,TLR10,TLR5,VSNL1 |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 1567 | 118 | AICDA,BCL2L11,BMP6,BTRC,C5,CAMK2B,CARD11,CCL26,CD1D,CD209,CD40,CD6,CD86,CEACAM1,CIITA,CLEC7A,CLU,COLEC10,CORO1A,CR2,CRTAM,CSF1R,CX3CR1,CYBB,CYP1A1,CYP1A2,DAPK1,DCLK1,DRD2,FCN1,FER1L6,FFAR2,FGFR2,FGG,FPR2,GBP5,GNLY,GUCY1A1,HAVCR2,HCK,HERC5,HLA-DPB1,HP,HTN3,ICAM2,IFNLR1,IL12A,IL23R,IL33,IL34,ITGAM,JAK2,JUN,KLK7,LGMN,LILRA2,LPO,LTF,LY9,MAP2K6,MAPK11,MRC1,MUC20,NCAM1,NECTIN2,NOS1,NOS2,NUGGC,OAS1,OASL,OPRK1,P2RX7,PADI4,PALM3,PELI1,PIK3AP1,POLR3A,PPP6C,PSMD9,PSTPIP1,PTAFR,PTGER4,PYGL,RAB29,RAET1G,RNF125,RNF216,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SERPINB9,SFTPA2,SH2D1A,SIGLEC11,SIGLEC14,SLAMF7,SMPDL3B,SPN,SRPK2,STAB1,SUSD4,TIGAR,TIMP4,TLR10,TLR5,TLR7,TMEM255A,TRAFD1,TXK,UBE2D1,ULBP1,ULBP2,ULBP3,VAV1,WAS,XPR1 |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 0.0e+00 | 0.0e+00 | 1813 | 468 | 54 | AFAP1L2,C5,CARD11,CD34,CD40,CD6,CD74,CD83,CD86,CLEC7A,CLU,CRTAM,CSF1R,CYBB,DRD2,FCN1,FFAR2,FLT4,GBP5,GPRC5B,HAVCR2,HHLA2,HLA-DPB1,IL12A,IL23R,IL33,IL7,JAK2,LILRA2,LY9,MAPK11,MBP,NFATC4,P2RX7,PAEP,PELI1,POLR3A,POSTN,PRKCZ,PRKD2,PTAFR,PTGER4,RAET1G,RNF125,SCAMP5,SCIMP,SEMA7A,SERPINB7,SPN,SULF2,TLR5,TLR7,TNFRSF8,TXK |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 1235 | 100 | ABCB1,ACVRL1,ANO3,ASIC1,ASIC3,ATP1B1,ATP8A2,AVPR1A,BMP6,CAMK2B,CASR,CBL,CD34,CD38,CD40,CHRNA10,CHRNA7,CHRNB2,CNGA1,CNGB1,CYB5R4,CYBB,CYP1A1,DRD2,DUSP1,ELOVL4,GNAT2,GPR4,GPR65,GRB2,GRIN1,GUCA1B,GUCA1C,HIGD1A,HOXA1,HSD11B2,HSP90AB2P,HTR2A,HVCN1,IFT20,IGFBP2,IL12A,JUN,KCNC1,KCND2,KCNK2,KCNMB1,KDM1A,LGMN,LRRC8C,LRRC8E,MAP7,MAPK10,NABP1,NDNF,NFATC4,NKX3-1,NMT2,NOS1,NOS2,NOX4,NPFFR2,NRXN1,NRXN2,OPRD1,P2RX7,P2RY1,PDE1B,PKD1L2,PLAT,PLEKHB1,POSTN,PSMD9,PTAFR,PTGER4,PTGIS,RYR1,SCEL,SCFD1,SEMA5B,SIRT4,SLC25A27,SLC29A1,SLC2A4,SLC4A10,SLC52A3,SLC6A4,ST8SIA1,STRBP,STX1A,TIGAR,TLR5,TLR7,TMEM150C,TNFRSF8,TRPA1,TRPM8,TRPV2,TRPV3,TSC22D2 |
| GO_HORMONE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 315 | 43 | ABCC8,ACVR1C,BMP6,BMP8A,CACNA2D2,CASR,CCN3,CD38,CPLX1,CPT1A,CRYM,CYB5R4,DOC2B,DRD2,ENHO,FAM3B,FFAR2,FGFR1,FGG,FKBP1B,GDF9,HNF4A,IL11,ILDR1,ILDR2,INHBB,JAK2,KALRN,KCNJ11,MAFA,NKX3-1,NKX6-1,NOS2,P2RY1,PSMD9,PTPRN2,SIRT4,SLC16A10,SLC16A2,SOX4,STX1A,SYBU,VSNL1 |
| GO_REGULATION_OF_TRANSPORTER_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 290 | 41 | ABCB1,ACTN2,AKAP6,AMIGO1,ANO9,ATP1B1,ATP1B2,CACNA2D1,CACNB2,CACNG7,CNIH2,CTTNBP2NL,DAPK1,DRD2,DRD4,EPHB2,FGF14,FKBP1B,FXYD7,GEM,GRIN1,HAP1,HTR3A,KCNC1,KCNE5,KCNJ11,MAPK8IP2,MRLN,NEDD4L,NOS1,NOS1AP,PTAFR,PTPN3,RASGRF1,RGN,RGS9,SCN3B,SCN4B,SGK2,SLN,TESC |
| GO_REGULATION_OF_METAL_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 400 | 49 | ACTN2,ADCYAP1R1,AKAP6,AMIGO1,ANXA9,ATP1B1,ATP1B2,CACNA2D1,CACNB2,CAMK2B,CASR,CNTN1,CORO1A,DRD2,DRD4,FGF14,FKBP1B,FXYD7,GEM,GNAO1,GRIN1,HAP1,HTR2A,IL16,KCNC1,KCNE5,KCNH2,KCNIP4,KCNMB1,KCNN2,LILRA2,MRLN,NEDD4L,NKAIN1,NOS1,NOS1AP,OPRD1,P2RX7,PTPN3,RGN,RGS9,SCN3B,SCN4B,SCN5A,SLC30A10,SLN,TESC,TRPV2,TRPV3 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1117 | 93 | ABHD6,ABO,ACER2,ACSL6,ACSM2A,ACSM3,ADA2,ADCY4,AICDA,AK5,AK9,ALG1L2,ASGR1,B3GAT2,B3GNT3,B4GALT4,B4GALT5,BACE2,CARD11,CHST4,CHST6,CSGALNACT1,CSPG5,DPY19L2,DPY19L2P2,ELOVL4,ESRRB,ESYT3,EXT1,EXTL2,FA2H,FBXO44,FMOD,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,GPAT4,GPC2,GUCY1A1,GUCY1A2,GUCY1B1,HS6ST1,HTR2A,HYAL4,ITIH5,ITM2C,LARGE2,LRGUK,MAGT1,MAN1C1,MFN1,MGAT4A,MPP1,MTAP,MUC20,NCCRP1,NDNF,OGA,OGDHL,P2RX7,PANK3,PDE10A,PDE4C,POMGNT2,PRELP,PRTFDC1,PYGL,SAMHD1,SDF2,SLC2A4,SPOCK2,SPOCK3,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,STT3B,SULF2,SULT2B1,SULT4A1,TBPL1,THEM4,TIGAR,TPST1,TUSC3,UGCG,UGT8,VCAN,XYLT1 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 1029 | 88 | ACVR2A,ACVRL1,ADAMTS3,AFF3,AHI1,ALS2,ALX4,ATOH1,ATP8A2,B4GALT5,BCL2L11,C5,CAMSAP3,CEBPA,CELF4,CHRD,CHRNA10,CYP26B1,DISP1,DLL4,DLX4,DSC3,EIF4A3,EOMES,EPB41L5,EPHB2,EXT1,FGFR1,FGFR2,FOXA1,FRAS1,FREM2,GCM1,GLI1,GRB2,GREM1,GREM2,HESX1,HEY2,HLX,HNF4A,HOXA1,HS6ST1,IRX5,KCNQ4,KPNA7,LAMA4,LMX1B,LRP6,MBP,MED21,MEOX1,MESP2,MMP16,MSX2,MYO18B,NES,NKD1,NKX3-1,NR5A2,NRP2,NTN1,NXN,PAX5,PCDH12,PCSK5,PLCD1,PLPP4,PNLDC1,POU4F3,RARB,RDH10,SALL2,SCEL,SCRIB,SH2B3,SNAI1,SOX4,SOX6,SPINT1,ST8SIA6,STK3,STPG4,SULF2,TCF7,TMEM100,VASH2,XYLT1 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 724 | 70 | ACE,ACVRL1,ADD2,AICDA,APC2,ARHGAP4,ARHGAP44,ARHGAP6,BCL11A,BMERB1,BMP6,CAMSAP3,CD38,CDKL3,CLEC16A,CLU,CORO1A,CRACD,CRMP1,DCC,DMRT1,DPYSL3,DRAXIN,DUSP1,EPHB2,FZD9,HIGD1A,IAPP,IQCJ-SCHIP1,ITM2C,JAM3,KDM1A,LCMT1,LDLRAD4,LINGO1,MAP6D1,MYLIP,NFATC4,NGFR,NR2F1,NTN1,OPRD1,PAX5,PLEKHH2,POSTN,PRKCZ,PTGER4,PTK2,RAB29,RAP1GAP,RGMA,RTN4RL2,SCAMP5,SCFD1,SCIN,SEC22B,SEMA4D,SEMA7A,SIRT4,SLIT1,SLN,SPTA1,SPTAN1,SPTB,TBC1D30,TIGAR,TMEFF2,TRIM9,TUBB4A,WAS |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1033 | 88 | ABHD5,ABHD6,ACHE,ACSL6,ACSM2A,ACSM3,ADCY4,ADCYAP1R1,AGAP2,AK5,AK7,AK9,ALOX15,ASMTL,BMX,CARD11,CSF1R,DDHD1,EFR3B,ELOVL4,ENPP6,ENTPD3,ESRRB,ETNPPL,FAM126B,FGFR3,FPR2,GDPD1,GPAT4,GUCA1B,GUCA1C,GUCY1A1,GUCY1A2,GUCY1B1,HTR2A,LIPH,LIPI,LPCAT2,LRGUK,MFN1,MIOX,MOCS2,MPP1,NKX2-1,NOS1,NOS2,OGDHL,P2RX7,P2RY1,PANK3,PCYT1B,PDE10A,PDE4C,PHOSPHO1,PI4KAP2,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,PLCD1,PLCH1,PLCL2,PLPP2,PLPP4,PLPPR4,PPIP5K1,PTAFR,PTGIS,PTK2,PYGL,SAMHD1,SBF1,SERAC1,SGPP1,SLA2,SLC44A3,SMPDL3B,SOCS4,SULT2B1,SULT4A1,TBPL1,THEM4,TIGAR,TPST1 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1813 | 1037 | 88 | ABCC8,ACHE,ACTN2,ACVR1C,ARHGAP44,BMP6,BMP8A,BTN2A2,C5,CABP1,CACNA2D2,CASR,CCN3,CD22,CD34,CD38,CD40,CDH1,CDH2,CHP2,CLSTN3,CNIH2,CPT1A,CRIPT,CRTAM,CSF1R,DCLK1,DISP1,DMAP1,DNAJC1,DOC2B,DRD2,DRD4,ENHO,EPB41L5,EPHB2,FCN1,FFAR2,FGG,FKBP1B,FZD9,GPC2,HAVCR2,HNF4A,HUWE1,IL1R2,IL33,INHBB,ITGAM,JAK2,KCNJ11,KDM1A,LILRA2,LRRC15,MAPK11,MBP,MESD,MMD,NEDD4L,NGFR,NKX3-1,NKX6-1,NOS2,OAZ2,P2RX7,PAEP,PLS1,POSTN,PRKCZ,PSMD9,PTGER4,RAB29,SCAMP5,SCFD1,SCRIB,SH3TC2,SIRT4,SOX4,SRCIN1,STX1A,STX6,SYBU,TBC1D1,TENM1,TLR10,TLR5,TMEM30A,VSNL1 |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 0.0e+00 | 0.0e+00 | 1813 | 1200 | 97 | AICDA,BTRC,C5,CAMK2B,CARD11,CCL26,CD1D,CD209,CD40,CD6,CEACAM1,CIITA,CLEC7A,CLU,COLEC10,CORO1A,CR2,CRTAM,CSF1R,CX3CR1,CYBB,DAPK1,DRD2,FCN1,FFAR2,FGG,FPR2,GBP5,GNLY,HAVCR2,HCK,HERC5,HLA-DPB1,HP,HTN3,ICAM2,IFNLR1,IL12A,IL23R,IL33,IL34,ITGAM,JAK2,KLK7,LGMN,LILRA2,LPO,LTF,LY9,MAP2K6,MRC1,MUC20,NCAM1,NECTIN2,NOS2,OAS1,OASL,OPRK1,P2RX7,PADI4,PELI1,PIK3AP1,POLR3A,PPP6C,PSMD9,PSTPIP1,PTAFR,RAET1G,RNF125,RNF216,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SERPINB9,SFTPA2,SH2D1A,SIGLEC11,SIGLEC14,SLAMF7,SMPDL3B,SPN,SRPK2,STAB1,SUSD4,TLR10,TLR5,TLR7,TRAFD1,TXK,UBE2D1,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 337 | 44 | ADCYAP1R1,ADRA1A,ALS2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,ARHGEF3,CADM4,CBL,CHN2,CYTH4,EPHB2,FGD2,FGD5,GPR4,GPR65,GRB2,JAK2,KALRN,MCF2L,MCF2L2,P2RY8,PLEKHG1,PLEKHG4B,PREX2,PSD,PSD2,RALGAPB,RALGPS1,RAP1GAP,RASGRF1,RHOV,ROBO1,SGSM3,SRGAP3,STARD8,TNFAIP1,TRIP10,VAV1 |
| GO_RESPONSE_TO_GROWTH_FACTOR | 0.0e+00 | 0.0e+00 | 1813 | 732 | 70 | ACVR1C,ACVR2A,ACVRL1,ADAMTS3,BMP6,CADM4,CASR,CBL,CGN,CHRD,COMP,CORO1A,CX3CR1,CYFIP2,DDC,DLL4,DOK5,EIF4A3,EPB41L5,FGF18,FGF21,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,FMOD,GAREM1,GDF6,GDF9,GRB2,GREM1,GREM2,HAP1,HEYL,HTR3A,JUN,KCNC1,LDLRAD4,LGMN,MAGI2,MAP2K3,MSX2,NEO1,NGFR,NKX2-1,NOS1,NOX4,NRP2,OPRD1,P2RY1,PAX9,POSTN,PRKCZ,PRKD2,PTK2,RGMA,ROBO1,RUNX3,SHISA2,SOSTDC1,SOX6,SPINT1,SULF2,SYAP1,TDGF1P3,TMEM100,UBE2D1,ZFYVE27,ZNF703 |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 766 | 72 | ACTN2,ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP44,ARHGAP6,ARHGEF10,CACNA1G,CACNA2D1,CACNB2,CALR,CCL26,CFL2,CNN3,CORO1A,CRACD,CSF1R,CSRP2,DPYSL3,DSC2,EMP2,ENAH,EPB41L5,ESAM,FCHSD1,FGD2,FGD5,FSCN3,GPR65,GRB2,HCK,HCN4,JAK2,JAM3,KCNE5,KCNH2,KCNJ5,KCNN2,MRTFA,MYH14,MYL2,NCK2,NCKAP1L,NEDD4L,NOS1AP,NOX4,PDLIM3,PLEKHH2,PLS1,PTGER4,RHOV,RND2,SAMD14,SCIN,SCN3B,SCN4B,SCN5A,SHTN1,SPECC1,SPTA1,SPTAN1,SPTB,TENM1,TESK2,TMEFF2,TNFAIP1,TNNI3,TNNT2,TRIP10,WAS,WASF3 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1189 | 96 | A2ML1,ACER2,AGAP2,ANXA9,AZIN2,BACE2,BTN2A2,C1QL4,C5,CADM4,CALR,CBL,CDKN2A,CDYL,CEACAM1,CEBPA,CELF4,CHRNA10,CHRNA7,CLEC16A,CLU,COL4A3,CPEB3,CST7,DAPK1,DNAJC1,DRD2,DUSP1,DUSP26,DUSP9,EIF4A3,ELFN1,EPHB2,FKBP1B,FTO,GFRA2,GREM1,GSKIP,HAP1,IAPP,IL1R2,INHBB,ITIH5,ITM2C,JUN,KDM1A,KIRREL2,KLHL31,KNG1,LAMP3,LDLRAD4,LIN28A,LMTK2,LRP6,LTF,MALSU1,MAPK8IP1,METTL14,NCK2,NCKAP1L,NDRG2,NGFR,NOS2,NXN,P2RX7,PAX5,PLAT,PPP1R14C,PPP1R16B,PPP1R1C,PRKAR2B,PRKCG,PRKCZ,PTPN3,RBM24,RGN,RPS6KA3,SAMD4B,SEMA4D,SERPINB7,SERPINB9,SH2B3,SH3RF2,SIRT4,SOCS4,SOX4,SPINK13,SPINT1,SPOCK2,SPOCK3,SRCIN1,TESC,TIMP3,TIMP4,VRK3,ZGPAT |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 872 | 78 | ACE,ADCY4,ADRA1A,AFAP1L2,AGAP2,ALS2,C5,CBL,CD40,CD74,CDK5R2,CDKN2A,CEACAM1,CEBPA,CHRNA7,CLU,CNTD2,CSF1R,DIRAS3,DOK7,DRD2,DRD4,DUSP1,DUSP26,DUSP9,EMP2,EPHB2,FGD2,FGF18,FGFR1,FGFR3,FPR2,GHR,GPRC5B,GREM1,GSKIP,HERC5,HIGD1A,HTR2A,IL23R,JAK2,KSR1,LRP6,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPRE3,MMD,MUC20,NCK2,NCKAP1L,NEURL1,NOX4,NPFFR2,P2RX7,PIK3R5,PRKAR2B,PRKCZ,PTK2,RGN,ROBO1,SH2B3,SLA2,SOCS4,SRCIN1,STK26,STK3,SYAP1,TENM1,TESC,TIGAR,TNFSF15,ZGPAT |
| GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 0.0e+00 | 0.0e+00 | 1813 | 369 | 46 | ADCYAP1R1,ADRA1A,AKAP6,ANXA9,ATP2B2,AVPR1A,CACNA2D1,CACNB2,CALB2,CCR6,CCRL2,CD38,CD52,CHRNA10,CNGB1,CORO1A,CX3CR1,CXCR2,DRD2,FAM155A,FKBP1B,FPR2,FZD9,GNAT2,GPR4,GPR65,GRIN1,HAP1,HTR2A,IAPP,JAK2,KNG1,LRP6,NOS1,P2RX7,P2RY1,P2RY8,PLCD1,PLCH1,PLCL2,PTGER4,RIC3,RYR1,RYR3,S1PR3,TRPA1 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 1741 | 125 | ACTN2,AGPS,AKAP6,ALS2,ANXA9,AP1B1,AP1S3,AP3B2,ARHGAP44,ARL14,ARL6,ATP1B1,BICDL1,BICDL2,CABP1,CALR,CAMSAP3,CBL,CCDC93,CD74,CDH1,CHP2,CLEC16A,CLMN,CLU,CNIH2,CORO1A,CPT1A,CSPG5,DCLK1,DDX25,DMAP1,DYNLL1,EGR2,EIF4A3,EMP2,EVI5,F5,GGA2,GOLGA7,GRTP1,HAP1,HOOK1,HUWE1,IFT20,IFT80,ITGAM,KIF13A,KIF13B,KIF5A,KIF5C,KLC3,KPNA1,KPNA5,KPNA7,LMTK2,LRP6,MAP1S,MAP6,MAP6D1,MAPK15,MIA3,MRLN,MYO10,NAPG,NGFR,NOS2,NTN1,OAZ2,PCDHGA3,PEX5L,PPP6C,PRKCZ,PTK2,RAB11FIP4,RAB17,RAB29,RAB33A,RAB37,RAB3B,RAB44,RAB9B,REEP1,RGPD3,RITA1,RPH3A,SCFD1,SCRIB,SCYL2,SEC22B,SERAC1,SGPP1,SGSM1,SGSM3,SGTB,SH3TC2,SIRT4,SLC66A2,SLIT1,SNX2,SPTA1,SPTAN1,SPTB,STAM2,STX11,STX12,STX1A,STX6,SYBU,SYMPK,SYTL5,TBC1D1,TBC1D29P,TBC1D30,TENM1,TMED6,TMEM30A,TUB,UBAP1,UBE2D1,USP6NL,WAS,ZDHHC11B,ZDHHC15,ZDHHC23 |
| GO_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1813 | 674 | 66 | BTN2A2,BTNL9,BTRC,CARD11,CD209,CD22,CD38,CD3D,CD40,CEACAM1,CLEC7A,CR2,CYFIP2,ELMO2,FCN1,FFAR2,FGG,FPR2,FYB2,GCSAML,GRB2,HAVCR2,HCK,HHLA2,HLA-DPB1,ICAM2,ITGAM,ITK,JUN,LGMN,LILRA2,LTF,MAP2K6,MAPK10,MUC20,MYO10,MYO1G,NCKAP1L,NECTIN2,PAX5,PELI1,PIGR,PIK3AP1,PLCL2,PLPP4,PRKD2,PSMD9,PTK2,RAB29,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SLA2,SMPDL3B,TESPA1,THEMIS2,TLR10,TLR5,TLR7,TRAC,TXK,UBE2D1,VAV1,WAS |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1016 | 86 | ACE,ACVR1C,ACVR2A,ADAM28,ADCYAP1R1,AVPR1A,AZIN2,BCL2L11,CALR,CCR6,CD38,CDYL,CELF4,CLIC5,CORIN,CYP1A1,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,EMP2,FAM9A,FAM9B,FSCN3,GDF9,GLI1,GRIN1,HAVCR2,HOOK1,HSD11B2,HVCN1,IFT20,IGFBP2,INHBB,IZUMO1,JAM3,KALRN,LGR5,LIN28A,LRGUK,MAPK8IP2,METTL14,NECTIN2,NEURL1,NOX5,NR6A1,NUP210L,P2RY1,PAEP,PARP11,PAX5,PCSK5,PCYT1B,PIWIL3,PRND,PTAFR,PTCHD3,PTGIS,RAD21L1,RGN,SBF1,SEPTIN4,SEPTIN6,SLC6A4,SLC9B1,SPANXA1,SPATA32,SPEF2,SPINK13,SSTR2,STRBP,TAF1L,TBPL1,TDRD7,TDRKH,TDRP,TESK2,TEX11,TFCP2L1,TRO,TSNAX,TSSK1B,VMP1 |
| GO_NEUROTRANSMITTER_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 168 | 30 | ADRA1A,ASIC1,CACNB2,CHRNB2,CHRNB4,CPLX1,CSPG5,DOC2B,DRD2,GAD1,GRIK5,HTR2A,MCTP2,NRXN1,NRXN2,P2RX7,P2RY1,PRKCG,PTPRN2,RIMS3,RPH3A,SCRIB,SLC18A2,STX11,STX1A,SYN3,SYP,SYT2,SYT5,TRIM9 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1813 | 1198 | 96 | ACVR2A,ACVRL1,AHI1,AHR,ALX4,ARID3B,ARID3C,ATOH1,BARX2,BCL9,BMP6,BORCS8-MEF2B,C1orf61,CD3D,CD40,CDK9,CEBPA,CHP2,CIITA,CREB3L3,DLX4,DMRT1,DRD2,EAF2,EBF2,EGR2,EOMES,ESRRB,FGFR2,FOXA1,FOXD2,GCM1,GLI1,GLIS3,GREM1,GRHL1,GRIN1,HEY2,HEYL,HLTF,HNF4A,HOXA1,IKZF5,IL11,IL33,ITGA6,JUN,KDM1A,KLF5,LHX4,LHX6,LMX1B,LRP6,MAFA,MED21,MEOX1,MRTFA,MYCL,NCK2,NFATC4,NGFR,NKX2-1,NKX3-1,NKX6-1,NOS1,NOTCH3,NPAS1,NPAS3,NR2F1,NR5A2,NR6A1,P2RY1,PAX5,PAX9,PITX2,POU2F3,POU4F1,POU4F3,PRKD2,RARB,RGMA,RORB,RPS6KA3,SALL2,SLC40A1,SMARCA1,SOX4,SOX6,SPDEF,STAT4,TAF1L,TBPL1,TXK,VGLL2,WAS,ZBTB7C |
| GO_ENSHEATHMENT_OF_NEURONS | 0.0e+00 | 0.0e+00 | 1813 | 137 | 27 | ACER3,ADAM22,AMIGO1,ARHGEF10,B4GALT5,BCAS1,CLU,CST7,DHH,EGR2,FA2H,GJC3,ITGAX,JAM3,MAL2,MBP,MYRF,NFASC,PLLP,PLP1,PTPRZ1,RARB,SH3TC2,TSPAN2,UGT8,WASF3,XK |
| GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 447 | 51 | ADRA1A,ALS2,ARHGAP4,ARHGAP44,ARHGAP6,ARHGEF10,ARHGEF3,CADM4,CBL,CDKN2A,CNKSR1,CYTH4,EPHB2,FGD2,FGD5,GPR4,GPR65,GRB2,JAK2,JUN,KALRN,KSR1,KSR2,MAPK11,MCF2L,MCF2L2,NGFR,NTN1,P2RY8,PLEKHG1,PLEKHG4B,PREX2,PSD,PSD2,RAB17,RAB29,RAB33A,RAB37,RAB3B,RAB44,RAB9B,RALGPS1,RASGRF1,RHOV,RND2,ROBO1,SGSM3,SHTN1,TNFAIP1,VAV1,WAS |
| GO_REGULATION_OF_DEVELOPMENTAL_GROWTH | 0.0e+00 | 0.0e+00 | 1813 | 348 | 44 | AKAP6,ARHGAP4,ATP8A2,BCL11A,BCL2L11,CACNA2D2,CACNG7,CDKL3,DCC,DRAXIN,DRD2,FGFR1,FGFR2,FGFR3,FTO,GHR,GLI1,GPAT4,HEY2,HLX,IL7,ISLR2,IST1,KCNK2,LGMN,MAPK11,NEDD4L,NKD1,NKX6-1,NPY1R,NTN1,OLFM1,PLS1,PTK2,RND2,SEMA4D,SEMA7A,SHTN1,SLC6A4,STK3,SYT2,TLL2,TRPV2,ZFYVE27 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1813 | 853 | 76 | ACE,ACVR2A,ADAM28,ADCYAP1R1,AVPR1A,AZIN2,BCL2L11,BRINP1,CALR,CCR6,CDYL,CELF4,CYP1A1,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,GDF9,GLI1,GRIN1,HAVCR2,HOOK1,IFT20,INHBB,IZUMO1,JAM3,KALRN,LGR5,LIN28A,LRGUK,MAP2K6,MAPK8IP2,METTL14,NECTIN2,NEURL1,NOX5,NPAS1,NR6A1,NUP210L,P2RY1,PAEP,PARP11,PAX5,PCYT1B,PIWIL3,PTAFR,PTCHD3,PTGIS,RAD21L1,RGN,SBF1,SEPTIN4,SEPTIN6,SLC6A4,SLIT3,SPANXA1,SPATA32,SPEF2,SSTR2,STRBP,TAF1L,TBPL1,TDRD7,TDRKH,TDRP,TESK2,TEX11,TIMP4,TSNAX,TSSK1B |
| GO_SKELETAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 526 | 56 | ACVR2A,ACVRL1,ALX4,ANXA9,BARX2,BMP6,BMP8A,CCN3,CHRD,CLEC3A,COL19A1,COMP,CSGALNACT1,CYP26B1,EIF4A3,EXT1,FGF18,FGFR1,FGFR2,FGFR3,GDF6,GREM1,HOXA1,IFT80,IRX5,LRP6,LTF,MMP13,MMP16,MSX2,P2RX7,PAX5,PCSK5,PHOSPHO1,PIP4K2A,PITX2,PRELP,PTGER4,RARB,RDH10,RGN,RPS6KA3,RUNX3,RYR1,SCIN,SEMA4D,SH2B3,SNAI1,SOX4,SOX6,SP5,SPNS2,SULF2,VCAN,VWA2,XYLT1 |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 669 | 65 | ACTN2,ACTR3C,ADAMTS14,ADAMTS3,ADD2,ALOX15,ANXA9,APC2,ARHGAP40,ARHGAP6,ARHGEF10,BMERB1,CAMSAP3,CCL26,CFL2,CHRNA7,CLU,COL5A3,COMP,CORO1A,CRACD,CRIPT,DPYSL3,EMP2,ENAH,ESAM,FCHSD1,FMOD,FSCN3,FSD1,GPR65,GRB2,GREM1,HCK,HOOK1,IAPP,JAK2,MAP1S,MAP6D1,MAPRE3,MYL2,NCK2,NCKAP1L,NOX4,PDLIM3,PLEKHH2,PLS1,PTGER4,RHOV,RND2,SAMD14,SCIN,SHTN1,SPTA1,SPTAN1,SPTB,STMND1,TENM1,TMEFF2,TNFAIP1,TNNT2,TPPP3,TUBB4A,WAS,WASF3 |
| GO_T_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 1813 | 468 | 52 | BTN2A2,CAMK4,CARD11,CCR6,CD1D,CD209,CD3D,CD6,CD70,CD74,CD83,CD86,CEACAM1,CLEC7A,CORO1A,CYP26B1,DLL4,DOCK8,EOMES,FGL1,FKBP1B,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,ITGAL,ITK,KIF13B,LY9,MAPK8IP1,NCK2,NCKAP1L,P2RX7,PELI1,PLA2G2D,PRKCZ,PTGER4,RAB29,RUNX3,SLA2,SOX4,SPN,SPTA1,TCF7,TESPA1,VAV1,WAS |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 547 | 57 | ACER2,ACER3,ADCYAP1R1,ADH1B,AKR1B15,AKR1D1,ALDH3B2,ALOX15,BMP6,CDH3,CEBPA,CHRNB2,CRYM,CYB5R1,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP39A1,CYP46A1,CYP4F12,CYP4F3,DDC,DHRS9,DISP3,DRD2,DRD4,FGFR1,FGFR4,GCNT4,GDPD1,GPR37,ITGAM,LGMN,MALRD1,MIOX,NR5A2,OSBPL6,P2RY1,PDE1B,PLCD1,PLCH1,PLCL2,PPIP5K1,PTAFR,RDH10,RDH12,SGPP1,SLC16A10,SLC16A2,SLC5A5,SNAI1,SRD5A2,SULT2B1,TIGAR,TPH1,TPH2 |
| GO_RESPONSE_TO_LIPID | 0.0e+00 | 0.0e+00 | 1813 | 930 | 80 | ACER2,ADCYAP1R1,AHR,AICDA,ATP1A3,AVPR1A,BCL2L11,BMP6,BRINP1,BRINP2,CALR,CASR,CBL,CD38,CD40,CD6,CD86,CLU,CPT1A,CX3CR1,CYBB,CYP1A1,CYP1A2,CYP26B1,DHH,DUSP1,ESRRB,FFAR2,FGFR2,FOXA1,GLDC,HAVCR2,HCK,HEYL,HNF4A,HOXB13,HSD11B2,IGFBP2,IL12A,IL23R,JAK2,JUN,KCNJ11,KCNMB1,LILRA2,LRP6,LTF,MAP4K1,MRC1,MSX2,NFATC4,NKX3-1,NOS1,NOS2,NR2C1,NR2F1,NR5A2,NR6A1,NUGGC,P2RX7,PALM3,PELI1,POSTN,POU4F1,PTAFR,PTGER4,RARB,RGS9,RORB,RPS6KA3,SCIMP,SLC6A1,SLC6A4,SLIT3,SSTR2,TAT,TESC,TIMP4,TPH2,ZNF703 |
| GO_FOREBRAIN_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 383 | 46 | ATOH1,AVPR1A,BMERB1,C21orf91,CDH1,CDH2,CDK5R2,CHRD,CHRNB2,CSF1R,DCLK1,DRAXIN,DRD2,EFNA2,EOMES,EPHB2,EPHB3,EXT1,FGFR1,FGFR2,GLI1,GNAO1,GRIN1,HAP1,HESX1,ITGAM,KCNC1,KDM1A,LHX6,LRP6,METTL14,NKX2-1,NOTCH3,NRP2,PAX5,PITX2,POU4F1,RARB,ROBO1,RTN4RL2,SCN5A,SEMA7A,SLC4A10,SLIT1,SSTR2,TACC1 |
| GO_GLYCOPROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 412 | 48 | ABO,ACER2,ALG1L2,ASGR1,B3GAT2,B3GNT3,B4GALT4,B4GALT5,BACE2,CHST4,CSGALNACT1,CSPG5,DPY19L2,DPY19L2P2,EXT1,EXTL2,FBXO44,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,HS6ST1,HYAL4,ITM2C,LARGE2,MAGT1,MAN1C1,MGAT4A,MUC20,NCCRP1,NDNF,OGA,POMGNT2,SDF2,SPOCK2,SPOCK3,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,STT3B,SULF2,TUSC3,VCAN,XYLT1 |
| GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 0.0e+00 | 0.0e+00 | 1813 | 327 | 42 | ACTN2,ADAM22,ANXA9,ARHGAP44,ARL6,ATP1B1,CACNB2,CACNG7,CDH1,CDH2,CPLX1,EFR3B,EMP2,EPHB2,FAM126B,FYB2,GGA2,GOLGA7,GRIN1,IFT20,KCNIP4,KCNJ11,KIF13A,LRP6,LRRC15,MAP7,MAPK10,NFASC,P2RY1,PLS1,PRKCZ,RAB29,RAB3B,SCN3B,SCRIB,TESC,TSPAN15,TSPAN33,TSPAN5,TUB,ZDHHC23,ZFYVE27 |
| GO_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 1005 | 84 | BTRC,C5,CAMK2B,CARD11,CCL26,CD1D,CD209,CD40,CD6,CEACAM1,CIITA,CLEC7A,CLU,COLEC10,CORO1A,CR2,CRTAM,CSF1R,CX3CR1,CYBB,DAPK1,DRD2,FCN1,FFAR2,FGG,FPR2,GBP5,HAVCR2,HCK,HERC5,HLA-DPB1,ICAM2,IFNLR1,IL12A,IL23R,IL34,ITGAM,JAK2,LGMN,LILRA2,LTF,LY9,MAP2K6,MRC1,MUC20,NCAM1,NECTIN2,NOS2,OAS1,OASL,PADI4,PELI1,PIK3AP1,POLR3A,PPP6C,PSMD9,PSTPIP1,PTAFR,RAET1G,RNF125,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SERPINB9,SFTPA2,SH2D1A,SIGLEC14,SLAMF7,SMPDL3B,SRPK2,SUSD4,TLR10,TLR5,TLR7,TRAFD1,TXK,UBE2D1,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_ACTION_POTENTIAL | 0.0e+00 | 0.0e+00 | 1813 | 133 | 26 | ADRA1A,AKAP6,ATP1B1,CACNA1G,CACNA1I,CACNA2D1,CACNB2,CHRNB2,CHRNB4,DSC2,FKBP1B,HCN2,HCN4,KCND2,KCNE5,KCNH2,KCNJ5,KCNN2,MYH14,NEDD4L,NOS1AP,PTPN3,SCN3A,SCN3B,SCN4B,SCN5A |
| GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 289 | 39 | AMIGO1,ATP8A2,C21orf91,CACNG7,CAMK1D,CAMK2B,CDKL3,CHODL,CNTN1,CPEB3,DPYSL3,FBXO31,FGFR1,FKBP1B,GPC2,IL1RAPL1,ISLR2,IST1,ITGA6,KALRN,KDM1A,LLPH,MAGI2,MAP6,NDNF,NEDD4L,NEURL1,NGFR,NTN1,RND2,ROBO1,S100A9,SEMA4D,SEMA7A,SHTN1,SYT2,TMEM30A,TRPV2,ZFYVE27 |
| GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | 0.0e+00 | 0.0e+00 | 1813 | 144 | 27 | CELF4,CHRNA10,CHRNA7,CHRNB2,CHRNB4,DRD2,DRD4,EIF4A3,FGF14,GABRA1,GABRA6,GABRB2,GABRD,GLRA3,GRID1,GRIK4,GRIK5,GRIN1,IGSF11,INSYN1,KCND2,MAPK8IP2,NRXN1,P2RX7,PRKCZ,SLC29A1,STX1A |
| GO_PEPTIDE_HORMONE_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 251 | 36 | ABCC8,ACVR1C,BMP8A,CACNA2D2,CASR,CCN3,CD38,CPLX1,CPT1A,CYB5R4,DOC2B,DRD2,ENHO,FAM3B,FFAR2,FGG,FKBP1B,HNF4A,ILDR1,ILDR2,INHBB,JAK2,KALRN,KCNJ11,MAFA,NKX6-1,NOS2,PSMD9,PTPRN2,SIRT4,SLC16A10,SLC16A2,SOX4,STX1A,SYBU,VSNL1 |
| GO_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 477 | 52 | ADGRB3,AGAP2,AGAP4,ALS2,APC2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,CCL26,CD40,CHN2,DEPDC5,DOCK8,EPHB3,EVI5,FGD2,FGD5,GNAO1,GPR65,GRTP1,ITGA6,JUN,KALRN,NCKAP1L,PREX2,PTK2,PTPRN2,RALGAPB,RAP1GAP,RASGRF1,RGN,RGPD3,RGS10,RGS7,RGS9,SBF1,SCRIB,SEMA4D,SGSM1,SGSM3,SRGAP3,STARD8,TBC1D1,TBC1D29P,TBC1D30,USP6NL,VAV1 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 976 | 82 | ACE,ADCY4,ADRA1A,AFAP1L2,AGAP2,ALS2,ARRDC4,C5,CBL,CD40,CD74,CDK5R2,CDKN2A,CEACAM1,CEBPA,CHRNA7,CLU,CNTD2,CSF1R,DIRAS3,DOK7,DRD2,DRD4,DUSP1,DUSP26,DUSP9,EIF4A2,EMP2,EPHB2,FGD2,FGF18,FGFR1,FGFR3,FPR2,GHR,GPRC5B,GREM1,GSKIP,HERC5,HIGD1A,HTR2A,IL23R,JAK2,KSR1,LRP6,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK15,MAPK8IP1,MAPRE3,MMD,MUC20,NCK2,NCKAP1L,NEURL1,NOX4,NPFFR2,P2RX7,PIK3R5,PPP1R3G,PRKAR2B,PRKCZ,PTK2,RGN,ROBO1,SH2B3,SLA2,SOCS4,SRCIN1,STK26,STK3,SYAP1,TENM1,TESC,TIGAR,TNFSF15,ZGPAT |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1813 | 1030 | 85 | ADAMTS20,ADCYAP1R1,AGAP2,AHI1,ATOH1,ATOX1,CAMK1D,CBL,CCN3,CD34,CD38,CD74,CLU,COMP,CORO1A,CRLF1,CSF1R,CX3CR1,CXCR2,DAPK1,DHRS2,DOCK8,DRAXIN,DRD2,DUSP1,FGF21,FGFR2,FGG,FLT4,FZD9,GABRB2,GPR37,GPR37L1,GREM1,GRIN1,HCK,HEY2,HIGD1A,IL2RB,IL7,ITGA6,JAK2,JUN,KDM1A,LAMP3,LGMN,LHX4,LRP6,LTF,MAPK8IP1,MAPK8IP2,MSX2,MT1F,NCKAP1L,NDNF,NES,NFATC4,NGFR,NUGGC,PELI1,POU4F1,PRAME,PRKCG,PRKCZ,PTK2,PTPRZ1,RARB,RB1CC1,RGN,RPS6KA3,SCG2,SEMA4D,SERPINB9,SH3RF2,SIRT4,SLC25A27,SLC30A10,SLC40A1,SNAI1,SOX4,TCF7,TEX11,TIGAR,TNFSF10,UNC5B |
| GO_PROTEIN_COMPLEX_OLIGOMERIZATION | 0.0e+00 | 0.0e+00 | 1813 | 493 | 53 | ACTN2,ANXA9,ASIC1,CALHM1,CD3D,CD74,CHRNB2,CHRNB4,CLU,CNGB1,CPT1A,DISP1,DPYSL3,FSD1,GBP5,GLRA3,GLS,GRB2,GRIN1,HBE1,IKZF5,ILDR1,KCNC1,KCNC3,KCND1,KCND2,KCNJ12,KCNV1,KCTD15,KCTD17,KCTD2,LRRC8C,MAGI2,MAT1A,OAT,PRKCZ,PRMT8,PRND,RYR1,RYR3,SAMHD1,SCUBE1,SEPTIN4,SHKBP1,SLC6A1,SLC6A4,SNX2,TNFAIP1,TRPA1,UPK1A,VWA2,WDCP,ZNHIT6 |
| GO_ACTIVATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 720 | 67 | BTN2A2,BTNL9,BTRC,C5,CARD11,CD209,CD22,CD38,CD3D,CEACAM1,CFHR1,CLEC7A,CLU,COLEC10,CR2,CYFIP2,ELMO2,FCN1,FFAR2,FGG,FPR2,FYB2,GCSAML,GRB2,HAVCR2,HCK,HHLA2,HLA-DPB1,ICAM2,ITGAM,ITK,LGMN,LILRA2,LTF,MAP2K6,MUC20,MYO10,MYO1G,NCKAP1L,NECTIN2,PAX5,PELI1,PIK3AP1,PLCL2,PLPP4,PRKD2,PSMD9,PTK2,RAB29,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SLA2,SMPDL3B,SUSD4,TESPA1,THEMIS2,TLR10,TLR5,TLR7,TRAC,TXK,UBE2D1,VAV1,WAS |
| GO_HEART_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 589 | 59 | ACTN2,ACVRL1,ADRA1A,AHI1,AKAP6,ANXA9,AP1B1,BICC1,C1orf127,CALR,DLL4,EOMES,FGFR1,FGFR2,FREM2,GLI1,GREB1L,GREM1,HEY2,HEYL,IFT20,JUN,KCNK2,LRP6,MAPK11,MESP2,MSX2,MYL2,MYO18B,NFATC4,NKX3-1,NOX4,NPY1R,NRP2,OLFM1,PCSK5,PDLIM3,PITX2,POU4F1,PTK2,RARB,RB1CC1,RBM20,RBM24,ROBO1,RYR1,SCN5A,SCUBE1,SGCZ,SLIT3,SNAI1,SOX4,SOX6,STK3,SYPL2,TDGF1P3,TMEM100,TNNI3,TNNT2 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1813 | 625 | 61 | ACTN2,ADAM22,ANXA9,ARHGAP44,ARL6,ATP1B1,BCL2L11,CACNB2,CACNG7,CDH1,CDH2,CPLX1,CRIPT,EFR3B,EMP2,EPHB2,FAM126B,FYB2,FZD9,GGA2,GOLGA7,GPC2,GRIK5,GRIN1,IFT20,ITGAL,ITGAM,ITGB7,KCNIP4,KCNJ11,KIF13A,LRP6,LRRC15,MAGI2,MAP7,MAPK10,MESD,NFASC,NRXN1,NRXN2,P2RY1,PIGR,PLS1,PRKCZ,RAB29,RAB3B,REEP1,SCN3B,SCRIB,SGTB,STX1A,TESC,TMEFF2,TSPAN15,TSPAN33,TSPAN5,TUB,ZDHHC11B,ZDHHC15,ZDHHC23,ZFYVE27 |
| GO_REGULATION_OF_SYNAPSE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1813 | 107 | 23 | ADGRB2,ADGRB3,ADGRL1,AMIGO1,CBLN2,CHRNB2,CLSTN3,EPHB2,EPHB3,GRIN1,IL1RAPL1,LRFN1,LRFN5,MDGA1,NRXN1,NTN1,NTNG2,PTK2,RAB17,SEMA4D,SLIT1,SLITRK2,SLITRK3 |
| GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1813 | 763 | 69 | ACVR1C,ACVRL1,ADRA1A,AKIRIN1,ATP8A2,AZGP1,BTN2A2,C1QL4,CCN3,CD86,CDKN2A,CEACAM1,CEBPA,CEND1,CLMN,COL4A3,CSF1R,DEC1,DHRS2,DLEC1,DLL4,DRD2,DUSP1,EAF2,ETV3,FABP6,FGFR2,GREM1,HAVCR2,HNF4A,IFNLR1,IFT80,IL12A,JAK2,JUN,KCNK2,MAGI2,MAPK11,MSX2,MYO16,NCK2,NDRG2,NEURL1,NGFR,NKX3-1,NOX4,PELI1,PLA2G2D,RARB,RGN,ROBO1,RUNX3,SCG2,SCIN,SH2B3,SLC6A4,SLIT3,SOX4,SPINT1,SPN,SSTR2,STK3,SULT2B1,TENM1,TES,TESC,TNFRSF8,VIPR2,ZBTB7C |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 1267 | 97 | ACTN2,ACTR3C,ADD2,AICDA,ALOX15,ANXA9,APC2,ARHGAP40,ARHGAP44,ARHGAP6,ARHGEF10,BCL2L11,BIK,BMERB1,CALR,CAMSAP3,CAPN6,CCL26,CDC14A,CDH2,CDK9,CFL2,CLEC16A,CLU,CORO1A,CPLX1,CRACD,CRIPT,CSF1R,DCDC2,DDHD1,DMRT1,DOC2B,DUSP1,ESAM,FCHSD1,FSD1,FZD9,GPR143,GPR65,GRB2,GRIK5,HAP1,HCK,HIGD1A,HUWE1,IAPP,IFT20,IQCJ-SCHIP1,JAM3,KCTD17,KDM1A,KPNA7,LCMT1,LRFN1,MAP1S,MAP6,MAP6D1,MAPK15,MAPRE3,MARCHF5,MSX2,NCK2,NCKAP1L,NES,NOS1,NOX4,NRXN1,P2RX7,PAX5,PIP4K2A,PLEKHH2,PRDM6,PRKD2,PTGER4,PTK2,RHOV,RND2,S100A9,SCFD1,SCIN,SEC22B,SIRT4,SLC2A4,SPTA1,SPTAN1,SPTB,STMND1,TBC1D30,TENM1,TIGAR,TMEFF2,TNFSF10,TRIM9,TUBB4A,USP6NL,WAS |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1813 | 767 | 69 | ABCC8,ACHE,ACVR1C,ARHGAP44,BMP6,BMP8A,BTN2A2,C5,CABP1,CACNA2D2,CASR,CCN3,CD22,CD34,CD38,CD40,CDH1,CHP2,CPT1A,CRTAM,CSF1R,DISP1,DMAP1,DNAJC1,DOC2B,DRD2,DRD4,ENHO,EPB41L5,FCN1,FFAR2,FGG,FKBP1B,HAVCR2,HNF4A,HUWE1,IL1R2,IL33,INHBB,ITGAM,JAK2,KCNJ11,LILRA2,MAPK11,MBP,NKX6-1,NOS2,OAZ2,P2RX7,PAEP,POSTN,PRKCZ,PSMD9,PTGER4,RAB29,SCAMP5,SCFD1,SCRIB,SH3TC2,SIRT4,SOX4,SRCIN1,STX1A,SYBU,TENM1,TLR10,TLR5,TMEM30A,VSNL1 |
| GO_LEUKOCYTE_MEDIATED_IMMUNITY | 0.0e+00 | 0.0e+00 | 1813 | 872 | 75 | ACE,ADA2,AICDA,AOC1,ARHGAP9,AZGP1,C5,CBL,CCR6,CD1D,CD40,CD70,CD74,CEACAM1,CHRNB4,CLU,CORO1A,CR2,CRTAM,CXCR2,CYBB,DYNLL1,EMP2,FCN1,FPR2,FRMPD3,GCA,GCNT3,GOLGA7,HAVCR2,HP,HUWE1,HVCN1,IL12A,IL23R,IST1,ITGAL,ITGAM,ITGAX,LAIR1,LTF,MAGT1,MGAM,MYO1G,NCKAP1L,NECTIN2,NFASC,ORMDL3,P2RX7,PIGR,PRKCZ,PTAFR,PTPRN2,PYGL,RAB37,RAB44,RAB9B,RAET1G,S100A9,SCIMP,SELL,SERPINB9,SH2D1A,SIGLEC14,SLA2,SLAMF7,SPTAN1,SUSD4,TMC6,TMEM30A,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_LEUKOCYTE_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1813 | 301 | 39 | ACE,AHR,BTN2A2,CARD11,CD1D,CD209,CD22,CD38,CD40,CD6,CD70,CD74,CD86,CHRNB2,CLU,CORO1A,CR2,CSF1R,DOCK8,FKBP1B,GREM1,HAVCR2,HHLA2,HLA-DPB1,IGFBP2,IL12A,IL23R,IL33,IL34,IL7,MAPK8IP1,NCK2,NCKAP1L,P2RX7,PELI1,PLA2G2D,PLCL2,SPN,SPTA1 |
| GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 522 | 54 | BMP6,BTRC,CARD11,CD1D,CD209,CEACAM1,CLEC7A,CRTAM,DRD2,FCN1,FFAR2,FGG,FPR2,GBP5,HAVCR2,HCK,HERC5,ICAM2,IFNLR1,IL12A,IL23R,ITGAM,JAK2,KLK7,LGMN,LILRA2,LTF,MAP2K6,MUC20,NECTIN2,PELI1,PIK3AP1,PSMD9,RAET1G,RNF125,RNF216,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SERPINB9,SFTPA2,SH2D1A,SIGLEC11,SMPDL3B,TIGAR,TLR10,TLR5,TLR7,TRAFD1,TXK,UBE2D1,VAV1 |
| GO_LEUKOCYTE_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 343 | 42 | ADD2,BTN2A2,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CEACAM1,CORO1A,CX3CR1,DOCK8,FGL1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,ITGAL,ITGB7,MIA3,NCK2,NCKAP1L,PELI1,PLA2G2D,PRKCZ,PTAFR,RUNX3,S100A9,SELL,SELPLG,SEMA4D,SPN,SPTA1,TESPA1,VAV1 |
| GO_ANATOMICAL_STRUCTURE_MATURATION | 0.0e+00 | 0.0e+00 | 1813 | 163 | 28 | ACVRL1,ADGRB3,B4GALT5,BCL11A,CDH3,CDK5R2,CEND1,CX3CR1,FGFR3,FGG,FOXA1,GPAT4,GREM1,GRIN1,HOXB13,IRX5,KDM1A,L3MBTL3,LTF,MSX2,NFASC,NKX6-1,PHOSPHO1,RYR1,SEMA4D,SRRM4,TFCP2L1,XYLT1 |
| GO_POSITIVE_REGULATION_OF_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 431 | 48 | ACHE,AVPR1A,BMP6,C5,CACNA1G,CACNA1I,CACNB2,CASR,CD34,CD38,CDK5R2,CHRNB2,CRTAM,CSF1R,DOC2B,DRD2,FCN1,FFAR2,FGFR1,FGG,HAVCR2,IL33,ILDR1,INHBB,ITGAM,JAK2,LILRA2,MAP2K6,MAPK11,MBP,NKX3-1,NKX6-1,P2RX7,P2RY1,PAEP,POSTN,PRKCZ,PSMD9,PTAFR,PTGER4,SCAMP5,SCIN,SLC6A1,SLC6A4,SOX4,STX1A,SYBU,VSNL1 |
| GO_RESPONSE_TO_TOXIC_SUBSTANCE | 0.0e+00 | 0.0e+00 | 1813 | 539 | 55 | ADCYAP1R1,AHR,AKR7A3,ASIC1,CBL,CDH1,CHRNA7,CHRNB2,CHRNB4,CYBB,CYP1A1,DDC,DHRS2,DMAP1,DRD2,DRD4,DUSP1,FGFR2,FKBP1B,GNAO1,GPR37,GPR37L1,GRIN1,GSTM3,HBA1,HBE1,HBG2,HP,HTR3A,JUN,KCNC1,KCNJ11,KCNMB1,KDM1A,LPO,MBP,MT1F,NKX6-1,NXN,OPRD1,PDE1B,PXDNL,RDH12,RGN,RGS10,RGS9,S100A9,SCFD1,SLC18A2,SLC2A4,SLC6A1,SLC6A14,SLC6A4,STK26,TRPA1 |
| GO_LYMPHOCYTE_ACTIVATION | 0.0e+00 | 0.0e+00 | 1813 | 736 | 67 | AHR,AICDA,BTN2A2,CAMK4,CARD11,CCR6,CD1D,CD209,CD22,CD38,CD3D,CD40,CD6,CD70,CD74,CD83,CD86,CEACAM1,CHRNB2,CLEC7A,CORO1A,CR2,CYP26B1,DLL4,DOCK8,EOMES,FGL1,FKBP1B,FZD9,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL11,IL12A,IL23R,IL7,ITGAL,ITK,KIF13B,LY9,MAPK8IP1,NCK2,NCKAP1L,P2RX7,PELI1,PLA2G2D,PLCL2,POLM,PRKCZ,PTGER4,RAB29,RUNX3,SLA2,SLAMF7,SOX4,SPN,SPTA1,TCF7,TESPA1,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 402 | 46 | ADGRB3,AGAP2,AGAP4,ALS2,APC2,ARAP2,ARHGAP15,ARHGAP4,ARHGAP40,ARHGAP44,ARHGAP6,ARHGAP9,ARHGEF10,CCL26,CD40,CHN2,DEPDC5,DOCK8,EVI5,GNAO1,GPR65,GRTP1,ITGA6,JUN,KALRN,NCKAP1L,PREX2,RALGAPB,RAP1GAP,RASGRF1,RGN,RGPD3,RGS10,RGS7,RGS9,SCRIB,SEMA4D,SGSM1,SGSM3,SRGAP3,STARD8,TBC1D1,TBC1D29P,TBC1D30,USP6NL,VAV1 |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 671 | 63 | ABO,ACER2,ACSL6,ADA2,ADCY4,AK5,AK9,ALG1L2,ASGR1,B3GAT2,B3GNT3,B4GALT4,B4GALT5,BACE2,CHST4,CHST6,CSGALNACT1,CSPG5,DPY19L2,DPY19L2P2,ELOVL4,EXT1,EXTL2,FA2H,FMOD,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,GPC2,GUCY1A1,GUCY1A2,GUCY1B1,HS6ST1,ITM2C,LARGE2,MAGT1,MAN1C1,MGAT4A,MTAP,MUC20,OGA,PANK3,POMGNT2,PRELP,PRTFDC1,PYGL,SDF2,SLC2A4,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,STT3B,TBPL1,TUSC3,UGCG,UGT8,VCAN,XYLT1 |
| GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 346 | 42 | ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,CACNA2D1,CACNB2,CACNG7,CNIH2,CORO1A,DAPK1,DRD2,DRD4,EPHB2,FGF14,FKBP1B,FXYD7,GEM,GRIN1,HAP1,KCNC1,KCNE5,KCNH2,KCNIP4,KCNJ11,KCNMB1,KCNN2,MAPK8IP2,MRLN,NEDD4L,NOS1,NOS1AP,NOX5,PTPN3,RASGRF1,RGN,RGS9,SCN3B,SCN4B,SCN5A,SLN,TESC |
| GO_INORGANIC_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 166 | 28 | ABCB1,ANO3,ANO9,CASR,CLCA3P,CLCN4,CLIC5,FGFR1,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GLRA3,LRRC8C,LRRC8E,NMUR1,PTAFR,SLC12A8,SLC1A4,SLC22A11,SLC4A10,SLC4A5,SLC4A8,SLC5A5,TTYH2,XPR1 |
| GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1813 | 483 | 51 | ABHD6,ACHE,ADCY4,AZGP1,BMP6,BMP8A,CD34,CD38,CDH3,CNGB1,CORO1A,CRACD,CSF1R,CYP26B1,CYP4F12,DRD2,EBF2,ESRRB,FA2H,FGF21,FTO,GRHL1,HTR2A,IAPP,IL7,ILDR2,JAK2,KDM1A,KSR2,LAMA4,LSR,LTF,MAP2K6,NOX4,P2RX7,PIGR,PLCL2,POTEE,POTEF,POTEI,PRKAR2B,RDH12,SLC40A1,SLN,TLE3,TRPM8,TRPV2,TUB,UGCG,USH2A,VSIG1 |
| GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 577 | 57 | ACE,ADCY4,ADRA1A,AFAP1L2,AGAP2,ALS2,C5,CD40,CD74,CDK5R2,CHRNA7,CLU,CSF1R,DOK7,DRD2,DRD4,DUSP9,EMP2,FGD2,FGF18,FGFR1,FGFR3,FPR2,GHR,GPRC5B,GREM1,HIGD1A,HTR2A,IL23R,JAK2,KSR1,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPRE3,MMD,MUC20,NCKAP1L,NEURL1,NOX4,P2RX7,PIK3R5,PRKAR2B,PRKCZ,PTK2,ROBO1,SRCIN1,STK26,STK3,SYAP1,TENM1,TIGAR,TNFSF15 |
| GO_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | 0.0e+00 | 0.0e+00 | 1813 | 214 | 32 | ADRA1A,CACNB2,CDH2,CHRNB2,CPLX1,CSPG5,DDC,DOC2B,DRD2,DRD4,FGF14,GRIK5,HTR2A,MAGI2,MAPK10,NRXN1,P2RX7,P2RY1,PRKCG,RAB3B,RIMS3,SCRIB,SLC17A8,SLC18A2,SLC2A4,STX11,STX1A,SYN3,SYP,SYT2,SYT5,TRIM9 |
| GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 167 | 28 | ASIC3,ATP2B2,CDC14A,CHRNA10,CHRNB2,CLIC5,COL4A3,CRYM,DCDC2,FGFR1,GABRB2,GJC3,GRM7,HOXA1,HTR2A,KCNQ4,MBP,MYH14,OTOA,PJVK,POU4F3,SLC17A8,SLC52A3,SRRM4,TMPRSS3,TRPA1,TUB,USH2A |
| GO_REGULATION_OF_EXOCYTOSIS | 0.0e+00 | 0.0e+00 | 1813 | 216 | 32 | ADRA1A,CACNA1G,CACNA1I,CACNB2,CDK5R2,CEACAM1,CHRNB2,CPLX1,CSPG5,DOC2B,DRD2,FGG,GRIK5,HAP1,HTR2A,IL1RAPL1,ITGAM,LGI3,P2RY1,PRKCG,PTAFR,RAB3B,RIMS3,SCAMP5,SEPTIN4,STX1A,SYP,SYT13,SYT2,SYT5,TRIM9,VSNL1 |
| GO_RESPONSE_TO_HORMONE | 0.0e+00 | 0.0e+00 | 1813 | 994 | 81 | ACTN2,ACVR1C,ADCY4,ADCYAP1R1,ADRA1A,ATP1A3,ATP6V0B,ATP6V1C2,AVPR1A,BCL2L11,BMP6,CALR,CBL,CD38,CEACAM1,CHRM4,CHRNA7,CHRNB2,CYBB,CYP1A2,DHH,DUSP1,EGR2,ENHO,ESRRB,FGF21,FOXA1,GHR,GRB2,HEYL,HNF4A,HOXB13,HSD11B2,IGFBP2,INHBB,JAK2,JUN,KCNJ11,LGR5,LRP6,MSX2,NKX2-1,NKX3-1,NKX6-1,NOS1,NOS2,NPFFR1,NPFFR2,NR2C1,NR2F1,NR5A2,NR6A1,POSTN,POU4F1,PRKAR2B,PRKCZ,PTAFR,PTGER4,PTK2,RARB,RGS10,RGS9,RORB,SLC2A4,SLC30A10,SLC5A5,SLC6A1,SLC6A4,SLIT3,SSTR2,STAT4,SYAP1,TAT,TIMP3,TIMP4,TNFSF10,TPH2,TUB,UGCG,VWA2,ZNF703 |
| GO_SENSORY_ORGAN_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 549 | 55 | ACHE,ACVRL1,AHI1,ARL6,ATOH1,ATP8A2,BCL2L11,BMP6,CEBPA,CELF4,CHRNA10,CRB1,CRYBB3,CYP1A1,CYP26B1,DLL4,EPHB2,ESRRB,FGFR1,FGFR2,FREM2,GABRB2,GNAT2,HESX1,HEY2,HOXA1,IFT20,IRX5,JUN,KCNK2,KCNQ4,LGR5,LRP6,MYCL,MYH15,NES,NKD1,NTN1,PITX2,PLPPR4,POU4F3,RAB11FIP4,RARB,RDH10,RORB,SALL2,SCRIB,SDK2,SLC17A8,SLC25A27,SLC4A5,TDRD7,TSPAN12,TUB,USH2A |
| GO_MULTI_ORGANISM_BEHAVIOR | 0.0e+00 | 0.0e+00 | 1813 | 67 | 18 | AVPR1A,BRINP1,CHRNB2,CX3CR1,DRD4,GAD1,GCNT4,GLS,GNB1L,GRID1,GRIN1,KALRN,MAPK8IP2,NRXN1,NRXN2,NRXN3,POU4F1,SLC6A4 |
| GO_GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 341 | 41 | ABO,ACER2,ALG1L2,ASGR1,B3GAT2,B3GNT3,B4GALT4,B4GALT5,BACE2,CHST4,CSGALNACT1,CSPG5,DPY19L2,DPY19L2P2,EXT1,EXTL2,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,HS6ST1,ITM2C,LARGE2,MAGT1,MAN1C1,MGAT4A,MUC20,OGA,POMGNT2,SDF2,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,STT3B,TUSC3,VCAN,XYLT1 |
| GO_DEVELOPMENTAL_CELL_GROWTH | 0.0e+00 | 0.0e+00 | 1813 | 233 | 33 | ADRA1A,AKAP6,ARHGAP4,BCL11A,CACNG7,CDKL3,CYFIP2,DCC,DCLK1,DRAXIN,GDF9,ISLR2,IST1,LLPH,NEDD4L,NKX6-1,NRN1L,NRP2,NTN1,OLFM1,POSTN,POU4F3,PRKCZ,RND2,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SYT2,TRPV2,ZFYVE27 |
| GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 259 | 35 | ALOX15,BTN2A2,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CORO1A,DOCK8,FGG,FOXA1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,ITGA6,KIF26B,MYO10,NCK2,NCKAP1L,PODXL,PRKCZ,PTAFR,RUNX3,SPTA1,TESPA1,VAV1 |
| GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 401 | 45 | ALOX15,BTN2A2,CALR,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CHRD,CORO1A,CSPG5,DOCK8,DUSP26,EMP2,EPB41L5,FGG,FOXA1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,ITGA6,JAK2,KIF26B,MYO10,NCK2,NCKAP1L,NDNF,PODXL,PRKCZ,PRKD2,PTAFR,RUNX3,SPOCK2,SPTA1,TESPA1,VAV1 |
| GO_SODIUM_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 221 | 32 | ASIC1,ASIC3,ATP1A3,ATP1B1,ATP1B2,CACNA1G,CACNA1I,CNTN1,DRD2,DRD4,FXYD7,HCN2,HCN4,NEDD4L,NKAIN1,NOS1,P2RX7,PTPN3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC13A3,SLC17A8,SLC24A4,SLC4A10,SLC4A5,SLC4A8,SLC5A5,SLC9B1,TESC |
| GO_REGULATION_OF_AXONOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 184 | 29 | AMIGO1,ARHGAP4,CDH2,CDKL3,CHODL,DCC,DRAXIN,EPHB2,EPHB3,GRIN1,ISLR2,IST1,KIF13B,LINGO1,LRRC4C,MAP6,NGFR,NKX6-1,NTN1,OLFM1,PTK2,RND2,ROBO1,SEMA4D,SEMA7A,SHTN1,TRPV2,XK,ZFYVE27 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1813 | 1559 | 110 | ABCB1,ABCC1,ANKRD6,ANXA9,ARMT1,BCL2L11,BTRC,CADM4,CAMK2B,CARD11,CCN3,CD1D,CD209,CD34,CD6,CD74,CDK9,CDKN2A,CEACAM1,CEBPA,CLEC7A,CLU,CREB3L3,CRTAM,CST7,DRD2,DUSP1,FCN1,FFAR2,FGD2,FGG,FKBP1B,FLT4,FPR2,GBP5,GDF6,GPR37,GPR37L1,GPRC5B,HAVCR2,HCK,HERC5,ICAM2,IFNLR1,IL12A,IL1R2,IL23R,IL33,ITGAM,JAK2,KCNK2,KDM1A,KLHL31,KLK7,KLKB1,KNG1,LGMN,LILRA2,LRFN5,LTF,MAP2K6,MAP4K1,MAPK8IP1,MAPK8IP2,MUC20,NCK2,NECTIN2,NKX3-1,NOS2,PELI1,PIK3AP1,PLAT,PRKCG,PSMD9,PTGER4,PTGIS,RAET1G,RB1CC1,RGMA,RGN,RNF125,RNF216,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SEMA7A,SERPINB9,SFTPA2,SH2B3,SH2D1A,SH3RF2,SIGLEC11,SLC30A10,SMPDL3B,SNAI1,STK26,STK3,TAFA3,TIGAR,TLR10,TLR5,TLR7,TNFRSF19,TRAFD1,TXK,UBE2D1,VAV1,WAS |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1813 | 709 | 64 | ABCC1,ACTN2,ADCY4,AHR,AKAP6,AMIGO1,AOC1,ATP1A3,ATP6V0B,ATP6V1C2,BCL11A,BCL2L11,CACNA2D1,CASR,CDH1,CEACAM1,CHRM4,CHRNA7,CHRNB2,CPEB3,CYBB,DDC,DRD2,DRD4,ENHO,FGF21,FPR2,GABRA1,GABRB2,GHR,GNAL,GNAO1,GRB2,GUCY1B1,HCN2,HCN4,HTR2A,HTR3A,HTR3B,INHBB,JAK2,KDM1A,KLF5,LGMN,NEURL1,NGFR,NKX6-1,NOX4,P2RX7,P2RY1,PRKAR2B,PRKCZ,PTAFR,PTK2,RGS10,RGS9,RYR1,RYR3,SLC2A4,SLC30A10,SLC5A5,SLC6A4,SYAP1,VWA2 |
| GO_UROGENITAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 331 | 40 | ACE,AHI1,BCL2L11,BMP6,CD34,COL4A3,CRLF1,CXCR2,CYP26B1,EAF2,EPHB2,EPHB3,FGFR1,FGFR2,FOXA1,FRAS1,GCNT3,GCNT4,GLI1,GPR4,GREB1L,GREM1,HEYL,HOXB13,IFT20,ITGA6,KIF26B,LGR5,LIN28A,MAGI2,NKX3-1,NOTCH3,PCSK5,PODXL,RARB,RDH10,RGN,SERPINB7,SOX4,SULF2 |
| GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 390 | 44 | AKIRIN1,AMIGO1,ATP8A2,C21orf91,CACNG7,CAMK1D,CAMK2B,CDKL3,CHODL,CNTN1,CPEB3,DPYSL3,FBXO31,FGFR1,FKBP1B,GPC2,HAP1,IL1RAPL1,ISLR2,IST1,ITGA6,KALRN,KCTD17,KDM1A,LLPH,MAGI2,MAP6,NDNF,NEDD4L,NEURL1,NGFR,NTN1,P2RX7,RND2,ROBO1,S100A9,SEMA4D,SEMA7A,SHTN1,SYT2,TENM1,TMEM30A,TRPV2,ZFYVE27 |
| GO_CELL_GROWTH | 0.0e+00 | 0.0e+00 | 1813 | 483 | 50 | ACVRL1,ADRA1A,AKAP6,ARHGAP4,AVPR1A,BCL11A,CACNG7,CCN3,CD38,CDKL3,CDKN2A,CEACAM1,CLSTN3,CYFIP2,DACT3,DCC,DCLK1,DRAXIN,EAF2,EPB41L5,GDF9,GNG4,GREM1,HNF4A,ISLR2,IST1,LLPH,MYL2,NEDD4L,NKX6-1,NRN1L,NRP2,NTN1,OLFM1,POSTN,POU4F3,PRKCZ,RND2,RPS6KA3,S100A9,SEMA4D,SEMA5B,SEMA7A,SGK2,SHTN1,SLIT1,SLIT3,SYT2,TRPV2,ZFYVE27 |
| GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 750 | 66 | ABCA5,ACVRL1,AKIRIN1,ARHGAP4,BCL11A,BMERB1,BRINP1,C1QL4,CALR,CCN3,CD38,CD74,CDKL3,CEACAM1,CHRD,CRMP1,DACT3,DCC,DISP3,DPYSL3,DRAXIN,EPHB2,ESRRB,FOXA1,GPR37L1,GREM1,HEY2,HLX,IAPP,ITM2C,LDLRAD4,LIN28A,LINGO1,LTF,MSX2,MYLIP,NFATC4,NGFR,NKX2-1,NKX6-1,NOTCH3,NR2F1,NTN1,PAEP,POSTN,PRAME,PRDM6,PTK2,RAB29,RARB,RGMA,RORB,RTN4RL2,RUNX3,S1PR3,SEMA4D,SEMA7A,SLC6A4,SNAI1,SOSTDC1,SOX6,SPDEF,TLCD3B,TMEM176B,USH2A,ZBTB46 |
| GO_DRUG_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 600 | 57 | ABCC1,ACHE,ADA2,ADH1B,AK9,ALDH3B2,ASRGL1,CD34,CHRNB2,CLEC7A,CLU,CSPG5,CTRC,CX3CR1,CYBB,CYP1A1,CYP1A2,CYP27A1,CYP2B6,CYP2J2,CYP2S1,CYP46A1,CYP4F12,DDC,DHRS9,DRD2,DRD4,GGTLC3,GLDC,GPR37,HAL,HBA1,HBE1,HBG2,HP,ITGAM,JAK2,LPCAT2,LPO,MAT1A,ME3,MTAP,NOS1,NOS1AP,NOS2,NOXRED1,OAT,OXCT2,PDE1B,PLA2G4A,PTGIS,PXDNL,RGN,SDS,SLC52A3,TAT,VCAN |
| GO_CELL_CELL_SIGNALING_BY_WNT | 0.0e+00 | 0.0e+00 | 1813 | 521 | 52 | AMER2,ANKRD6,APC2,ARL6,ATP6V1C2,BCL9,BICC1,BTRC,CDH2,CDH3,CPZ,DACT3,DCDC2,DRAXIN,DRD2,EDA,FGFR2,FZD9,GLI1,GNAO1,GNAT2,GPRC5B,GREM1,GSKIP,IFT20,IFT80,IGFBP2,LGR5,LRP6,MAGI2,MAPK8IP1,MAPK8IP2,MARK1,MESD,NDRG2,NFATC4,NKD1,NXN,PSMD9,RNF43,SCEL,SCYL2,SHISA2,SOSTDC1,SOX4,STK3,SULF2,TCF7,TCF7L1,TLE3,TSPAN12,ZNF703 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1005 | 80 | ADH1B,ADHFE1,AGMO,AGPS,AKR1B15,AKR1D1,AKR7A3,AKR7L,ALDH3B2,ALOX15,AOC1,ASPHD2,COX7B2,CPT1A,CPT1C,CRYM,CRYZL1,CYB5R1,CYB5R4,CYBB,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2B6,CYP2J2,CYP2S1,CYP39A1,CYP46A1,CYP4F12,CYP4F22,CYP4F3,CYP4F8,CYP4X1,DHRS2,DHRS9,ESRRB,ETFBKMT,FA2H,FADS6,FTO,GLDC,HIGD1A,HSD11B1L,HSD11B2,HSD17B6,HSDL2,KDM1A,LPO,MDH1,ME3,MIOX,NFATC4,NLRP11,NOA1,NOS1,NOS2,NOX4,NOX5,NOXRED1,NXN,OGDHL,PCDH12,PLIN5,PPP1R3G,PTGIS,PTGR1,PXDNL,PYGL,RB1CC1,RDH10,RDH12,SIRT4,SRD5A2,STAB1,TIGAR,TPH1,TPH2,TSTD1,UQCRHL |
| GO_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 0.0e+00 | 0.0e+00 | 1813 | 268 | 35 | ACTN2,ANXA9,ARHGAP44,ARL6,ATP1B1,CACNB2,CDH1,CDH2,EFR3B,EMP2,EPHB2,FAM126B,FYB2,GGA2,GOLGA7,IFT20,KCNIP4,KCNJ11,KIF13A,LRP6,LRRC15,MAP7,NFASC,P2RY1,PLS1,PRKCZ,RAB3B,SCN3B,SCRIB,TESC,TSPAN15,TSPAN33,TSPAN5,ZDHHC23,ZFYVE27 |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 0.0e+00 | 1813 | 687 | 62 | ACHE,ACVRL1,AKIRIN1,ALOX15,ANXA9,BCL9,CADM4,CCN3,CD34,CD40,CDH3,CEACAM1,CLEC7A,COMP,CX3CR1,CYP1A1,DOCK8,DPYSL3,DRD2,F5,FGFR1OP2,FGFR2,FGG,FKBP1B,FZD9,GLI1,GPR4,HBE1,HBG2,HNF4A,HOXB13,INHBB,JAK2,JAM3,JUN,KCNK2,KDM1A,KLF5,KLKB1,KNG1,MIA3,MRLN,MSX2,NDNF,P2RX7,P2RY1,PIK3R5,PLAT,PLLP,POSTN,PRKAR2B,PRKCG,RGMA,RTN4RL2,SCRIB,SCUBE1,SH2B3,SULF2,TMEFF2,TMPRSS4,VAV1,WAS |
| GO_MUSCLE_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 383 | 43 | ACTN2,ADGRB3,ADRA1A,AKAP6,AVPR1A,BARX2,BCL9,BOC,CACNA2D2,CALR,CCN3,CDH15,CDH2,CDK9,CFL2,COMP,CYP26B1,DYRK1B,FBXO40,FGFR2,GREM1,HEY2,IFT20,KDM1A,KLF5,MAPK11,MRTFA,MYL2,MYO18B,NFATC4,NOS1,NOX4,OLFM2,PRDM6,RARB,RBM24,RBM38,RYR1,SGCZ,SOX6,SYPL2,TNNT2,XK |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 655 | 60 | ACE,ADCY4,ADRA1A,AFAP1L2,AGAP2,ALS2,ARRDC4,C5,CD40,CD74,CDK5R2,CHRNA7,CLU,CSF1R,DOK7,DRD2,DRD4,DUSP9,EMP2,FGD2,FGF18,FGFR1,FGFR3,FPR2,GHR,GPRC5B,GREM1,HIGD1A,HTR2A,IL23R,JAK2,KSR1,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK15,MAPRE3,MMD,MUC20,NCKAP1L,NEURL1,NOX4,P2RX7,PIK3R5,PPP1R3G,PRKAR2B,PRKCZ,PTK2,ROBO1,SRCIN1,STK26,STK3,SYAP1,TENM1,TIGAR,TNFSF15 |
| GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 540 | 53 | BCL2L11,BMP6,BTRC,CARD11,CD1D,CD209,CD74,CDK9,CLEC7A,CRTAM,CSF1R,FCN1,FFAR2,FGG,FPR2,GBP5,HAVCR2,HCK,ICAM2,IL12A,INHBB,ITGAM,JUN,KLK7,LGMN,LILRA2,LTF,MAP2K6,MUC20,NECTIN2,NOS2,NR5A2,P2RY1,PELI1,PIK3AP1,PSMD9,PTAFR,RAET1G,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SH2D1A,SMPDL3B,SRPK2,TLR10,TLR5,TLR7,TMPRSS2,TXK,UBE2D1,VAV1 |
| GO_COGNITION | 0.0e+00 | 0.0e+00 | 1813 | 298 | 37 | ADGRB3,ASIC1,BRINP1,CAMK4,CHRNA7,CHRNB2,CPEB3,CX3CR1,DRD2,EGR2,EIF4A3,EPHB2,FZD9,GRIN1,HOXA1,HTR2A,IFT20,JUN,KALRN,KCNK2,LGMN,MAGT1,MAPK8IP2,NFATC4,NRXN1,NRXN2,NRXN3,PDE1B,PRKAR2B,PRKCG,PRKCZ,PTPRZ1,RASGRF1,SLC1A4,SLC6A1,SLC6A4,TUSC3 |
| GO_NEURON_PROJECTION_EXTENSION | 0.0e+00 | 0.0e+00 | 1813 | 168 | 27 | ARHGAP4,BCL11A,CACNG7,CDKL3,CYFIP2,DCLK1,DRAXIN,ISLR2,LLPH,NEDD4L,NKX6-1,NRN1L,NRP2,NTN1,OLFM1,POSTN,POU4F3,PRKCZ,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,SYT2,TRPV2,ZFYVE27 |
| GO_LIPID_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1813 | 417 | 45 | ABCA5,ABCB1,ABCC1,ABCG4,ABHD5,ACE,ACVR1C,ANO3,ANO9,ANXA9,ATP8A2,BMP6,CEACAM1,CLU,CPT1A,DISP3,DRD2,DRD4,ESYT3,FABP6,FFAR2,FTO,GDF9,GULP1,LRP6,MAP2K6,NKX3-1,NOS2,OSBPL6,P2RX7,PDZD8,PLA2G2D,PLA2G4A,PLIN5,SERAC1,SGPP1,SLC27A6,SLC66A2,SLCO2B1,SPNS2,STX12,TMEM30A,UGCG,XKR4,XKR5 |
| GO_ENDOCYTOSIS | 0.0e+00 | 0.0e+00 | 1813 | 661 | 60 | ACHE,AHI1,ALOX15,ANXA9,ASGR1,BMP2K,CALR,CBL,CD209,CD22,CD6,CEACAM1,CLEC7A,CLU,CXCR2,DRD2,DRD4,FCHO1,FCN1,FPR2,GHR,GRB2,GREM1,GULP1,HBA1,HP,ILDR1,ITGAM,LRP6,MAGI2,MAPK8IP1,MAPK8IP2,MIA3,MRC1,NCKAP1L,NEDD4L,NEURL1B,NOSTRIN,PSTPIP1,RHOV,SCAMP5,SCGB3A2,SCRIB,SCYL2,SLC2A4,SNX2,STAB1,STX1A,SYP,SYT2,SYT5,TMPRSS15,TMPRSS2,TMPRSS3,TMPRSS4,TRIP10,TUB,WAS,XKR4,XKR5 |
| GO_INSULIN_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 206 | 30 | ABCC8,ACVR1C,BMP8A,CACNA2D2,CASR,CCN3,CD38,CPLX1,CPT1A,CYB5R4,DOC2B,DRD2,ENHO,FAM3B,FKBP1B,HNF4A,ILDR2,INHBB,JAK2,KCNJ11,MAFA,NKX6-1,NOS2,PSMD9,PTPRN2,SIRT4,SOX4,STX1A,SYBU,VSNL1 |
| GO_ERK1_AND_ERK2_CASCADE | 0.0e+00 | 0.0e+00 | 1813 | 316 | 38 | ADRA1A,ALOX15,BTN2A2,C1QL4,CASR,CCL26,CD74,CEACAM1,CHRNA10,CHRNA7,CSF1R,DRD2,DUSP1,DUSP26,EPHB2,FGF18,FGF21,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,HAVCR2,HTR2A,JUN,NDRG2,NOX4,P2RY1,PRKCZ,PRKD2,PTGER4,SCIMP,SEMA7A,SLC30A10,TIMP3,VRK3 |
| GO_REGULATION_OF_HORMONE_SECRETION | 0.0e+00 | 0.0e+00 | 1813 | 260 | 34 | ABCC8,ACVR1C,BMP6,BMP8A,CACNA2D2,CASR,CCN3,CD38,CPT1A,DOC2B,DRD2,ENHO,FFAR2,FGFR1,FGG,FKBP1B,GDF9,HNF4A,IL11,ILDR1,INHBB,JAK2,KALRN,KCNJ11,NKX3-1,NKX6-1,NOS2,P2RY1,PSMD9,SIRT4,SOX4,STX1A,SYBU,VSNL1 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 804 | 68 | ABCC1,BTRC,CARD11,CCN3,CD1D,CD209,CD6,CEACAM1,CEBPA,CLEC7A,CREB3L3,CRTAM,CST7,DRD2,FCN1,FFAR2,FGG,FPR2,GBP5,GPRC5B,HAVCR2,HCK,HERC5,ICAM2,IFNLR1,IL12A,IL1R2,IL23R,IL33,ITGAM,JAK2,KLK7,KLKB1,LGMN,LILRA2,LRFN5,LTF,MAP2K6,MUC20,NECTIN2,NOS2,PELI1,PIK3AP1,PSMD9,PTGER4,PTGIS,RAET1G,RNF125,RNF216,RPS6KA3,S100A9,SAMHD1,SCIMP,SCRIB,SEMA7A,SERPINB9,SFTPA2,SH2D1A,SIGLEC11,SMPDL3B,TAFA3,TLR10,TLR5,TLR7,TRAFD1,TXK,UBE2D1,VAV1 |
| GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 184 | 28 | B4GALT5,C21orf91,CEND1,CHRNB2,CSF1R,DCC,DCLK1,DLL4,DRAXIN,DRD2,EOMES,EPHB2,EPHB3,FGFR2,KNDC1,LHX4,LHX6,LRP6,MDGA1,MNX1,NKX2-1,NKX6-1,NRP2,POU4F1,PTK2,ROBO1,SLC4A10,SOX4 |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1813 | 567 | 54 | ACTN2,AHI1,AKIRIN1,ARHGAP44,ARL6,CDC14A,CEP19,CEP83,CFAP53,CYFIP2,DCDC2,DNAAF3,DNAH7,DNAI1,DPYSL3,DYNLL1,EMP2,FGD2,FGD5,GFY,HAP1,HYDIN,IFT20,IFT80,IQUB,ITGA6,JHY,KCTD17,KIF27,KLF5,LRGUK,MAPK15,MYO10,NCK2,NCKAP1L,NEURL1,NTN1,P2RX7,PODXL,PPP1R16B,PRKAR2B,RAB17,RAP1GAP,RHOV,SEPTIN6,SFI1,SHTN1,STK26,TBC1D30,TEKT1,TENM1,TUBB4A,WAS,WASF3 |
| GO_HORMONE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 236 | 32 | ACE,ACHE,ADH1B,AKR1B15,AKR1D1,BACE2,BMP6,CORIN,CRYM,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2S1,CYP46A1,DHRS2,DHRS9,FGFR1,FOXA1,GCNT4,GHR,HSD11B2,HSD17B6,PCSK2,PCSK5,RBP1,RDH10,RDH12,SLC16A10,SLC16A2,SLC5A5,SRD5A2 |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1813 | 737 | 64 | ACER2,ACVR1C,ARHGEF3,BCL2L11,BIK,CAMK1D,CASP14,CD40,CDKN2A,CLEC7A,CLU,COL4A3,CXCR2,DAPK1,DUSP1,FGD2,FOXA1,FZD9,GRIK5,GRIN1,HBA1,HP,IAPP,IL12A,INHBB,ITGA6,ITGAM,ITM2C,JAK2,JUN,KALRN,KCNK2,KNG1,MAP2K6,MCF2L,MSX2,NCK2,NEURL1,NFATC4,NGFR,NKX3-1,NOX4,OLFM1,P2RX7,PNMA2,POU4F1,PTGIS,RARB,ROBO1,S100A9,SCIMP,SCIN,SCRIB,SEPTIN4,SOX4,SPDEF,SRPK2,STK3,TIGAR,TIMP3,TNFRSF8,TNFSF10,TNFSF15,VAV1 |
| GO_RESPONSE_TO_XENOBIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1813 | 291 | 36 | AHR,AKR7A3,AKR7L,AOC1,ASIC1,CES3,CHRNB2,CYP1A1,CYP1A2,CYP26B1,CYP2B6,CYP2J2,CYP2S1,CYP46A1,DRD2,DRD4,GHR,GNAO1,GRIN1,GSTM3,HNF4A,HTR2A,HTR3A,LPO,NAT2,PDE1B,PRKAR2B,PRKCG,PTAFR,RGS10,RGS9,RYR1,RYR3,SLC18A2,SLC6A1,TIGAR |
| GO_TISSUE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 670 | 60 | ACVRL1,AHI1,ANKRD6,BTRC,CAMSAP3,CASR,CEACAM1,CHRD,CSF1R,CXCR2,DLL4,EOMES,EPB41L5,FGFR1,FGFR2,FOXA1,FRAS1,FREM2,GCM1,GCNT3,GCNT4,GRB2,GREB1L,GREM1,HESX1,HEY2,HEYL,HOXB13,IFT20,ITGAX,KIF26B,LGR5,LRP6,MAGI2,MESP2,MSX2,MYL2,NFATC4,NKD1,NKX2-1,NKX3-1,NRP2,NTN1,PODXL,POU4F1,PRKD2,PSMD9,RDH10,ROBO1,SCRIB,SNAI1,SOSTDC1,SOX4,SPINT1,STK3,TMEFF2,TMEM100,TNNI3,TNNT2,VWA2 |
| GO_LEUKOCYTE_MEDIATED_CYTOTOXICITY | 0.0e+00 | 0.0e+00 | 1813 | 106 | 21 | AZGP1,CD1D,CEACAM1,CORO1A,CRTAM,EMP2,HAVCR2,IL12A,IL23R,ITGAM,NECTIN2,NOS2,P2RX7,RAET1G,SERPINB9,SH2D1A,SLAMF7,ULBP1,ULBP2,ULBP3,VAV1 |
| GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 654 | 59 | ABHD5,ACSL6,ACSM2A,ACSM3,ADH1B,AKR1D1,ALOX15,ASRGL1,AVPR1A,CD74,CEACAM1,CPT1A,CPT1C,CSPG5,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2B6,CYP2J2,CYP2S1,CYP39A1,CYP46A1,CYP4F12,CYP4F3,CYP4F8,DHRS9,ELOVL4,ESRRB,ETFBKMT,FA2H,FADS6,FGFR4,GAD1,GPAT4,HAL,HTR2A,MALRD1,ME3,NR5A2,OGDHL,OSBPL6,P2RX7,PLA2G4A,PLIN5,PLP1,PRKAR2B,PTGIS,PTGR1,RBP1,RDH10,RGN,SDS,SIRT4,SLC27A6,THEM4,TIGAR,VCAN,VNN2 |
| GO_SEXUAL_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1813 | 847 | 70 | ACE,ACVR2A,ADAM28,ADCYAP1R1,AVPR1A,AZIN2,BCL2L11,CALR,CCR6,CDYL,CELF4,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,GDF9,GLI1,GRIN1,HOOK1,HVCN1,IFT20,INHBB,IZUMO1,JAM3,LGR5,LIN28A,LRGUK,MAPK8IP2,METTL14,NECTIN2,NEURL1,NOX5,NR6A1,NUP210L,P2RY1,PAEP,PARP11,PAX5,PCYT1B,PIWIL3,PRND,PTCHD3,RAD21L1,RGN,SBF1,SEPTIN4,SEPTIN6,SLC6A4,SLC9B1,SPANXA1,SPATA32,SPEF2,SPINK13,SSTR2,STRBP,TAF1L,TBPL1,TDRD7,TDRKH,TDRP,TESK2,TEX11,TSNAX,TSSK1B |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 0.0e+00 | 1813 | 940 | 75 | AICDA,ANXA9,AP1B1,AP1S3,ASGR1,BCL2L11,BTRC,CBL,CD1D,CD209,CD74,CD86,CDH1,CDHR3,CDK9,CEBPA,CLEC7A,CR2,CSF1R,CX3CR1,DYNLL1,EIF4A2,FCN1,GNLY,GRB2,GUCY1A1,HCK,HTN3,HTR2A,IL16,IL2RB,INHBB,IST1,ITGB7,JUN,KPNA1,KPNA5,KPNA7,LAMP3,LRRC15,LTF,MRC1,NCAM1,NECTIN2,NEDD4L,NMT2,NOS2,NR5A2,NRP2,OAS1,OASL,OGA,P2RX7,PCSK5,PDZD8,POU2F3,RAB11FIP4,RAB29,RAET1G,RNF216,RTN3,S100A9,SCRIB,SELPLG,SEPTIN6,SERPINB9,SRPK2,TMPRSS2,UBAP1,UBN1,ULBP1,ULBP2,ULBP3,USP6NL,XPR1 |
| GO_GLYCOSYLATION | 0.0e+00 | 0.0e+00 | 1813 | 267 | 34 | ABO,ACER2,ALG1L2,ASGR1,B3GAT2,B3GNT3,B4GALT4,B4GALT5,CHST4,DPY19L2,DPY19L2P2,EXT1,EXTL2,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,LARGE2,MAGT1,MAN1C1,MGAT4A,MUC20,OGA,POMGNT2,SDF2,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,STT3B,TUSC3 |
| GO_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 0.0e+00 | 1813 | 52 | 15 | AVPR1A,BRINP1,CHRNB2,CX3CR1,DRD4,GAD1,GNB1L,GRID1,GRIN1,KALRN,MAPK8IP2,NRXN1,NRXN2,NRXN3,SLC6A4 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 0.0e+00 | 0.0e+00 | 1813 | 561 | 53 | ALOX15,AOC1,AVPR1A,BMP6,CACNA1G,CALR,CASR,CDH1,CEBPA,CHP2,CPNE4,CYBB,CYP1A1,CYP1A2,DRD2,DUSP1,EIF4A3,FGG,FKBP1B,GNAO1,GPR37,GPR37L1,GUCY1B1,HBA1,HP,HVCN1,IGFBP2,JUN,KCNC1,KCNMB1,LGMN,MAPK10,MT1F,NEDD4L,NFATC4,P2RX7,RGN,RYR1,RYR3,SCN5A,SLC30A10,SLC30A3,SLC40A1,SLC6A1,STK26,SYT13,SYT2,SYT5,TAT,TIGAR,TNNT2,TPH2,TRPA1 |
| GO_MALE_GAMETE_GENERATION | 0.0e+00 | 0.0e+00 | 1813 | 562 | 53 | ACE,ACVR2A,ADAM28,ADCYAP1R1,AZIN2,BCL2L11,CALR,CCR6,CDYL,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,GLI1,HOOK1,IFT20,JAM3,LRGUK,METTL14,NECTIN2,NEURL1,NUP210L,PAEP,PARP11,PAX5,PCYT1B,PIWIL3,PTCHD3,RAD21L1,RGN,SBF1,SEPTIN4,SEPTIN6,SPANXA1,SPATA32,SPEF2,SSTR2,STRBP,TAF1L,TBPL1,TDRD7,TDRKH,TDRP,TESK2,TEX11,TSNAX,TSSK1B |
| GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1813 | 514 | 50 | ABCC1,BTRC,CARD11,CD1D,CD209,CD6,CEBPA,CLEC7A,CREB3L3,CRTAM,FCN1,FFAR2,FGG,FPR2,GBP5,GPRC5B,HAVCR2,HCK,ICAM2,IL12A,IL33,ITGAM,JAK2,KLK7,KLKB1,LGMN,LILRA2,LTF,MAP2K6,MUC20,NECTIN2,PELI1,PIK3AP1,PSMD9,PTGER4,RAET1G,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SH2D1A,SMPDL3B,TAFA3,TLR10,TLR5,TLR7,TXK,UBE2D1,VAV1 |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1813 | 614 | 56 | AHR,AKAP6,AOC1,ATP1A3,BCL2L11,BTRC,CALR,CASR,CDH1,CEBPA,CHRM4,CLU,CYP1A1,DRD2,DRD4,ESRRB,FOXA1,GABRA1,GABRB2,GNAL,GNAO1,HCN2,HCN4,HEYL,HNF4A,HTR2A,HTR3A,HTR3B,ITGA6,JAK2,KCNMB1,KDM1A,KLF5,LRP6,MSX2,NFATC4,NKX3-1,NOX4,NR2C1,NR2F1,NR5A2,NR6A1,P2RX7,P2RY1,POU4F1,PTAFR,RARB,RGS9,RORB,RYR1,RYR3,SLC5A5,SLC6A4,SP5,SSTR2,ZNF703 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 823 | 68 | A2ML1,ANXA9,C5,CABP1,CAMSAP3,CBL,CDKN2A,CEACAM1,CEBPA,CNN3,COL4A3,CST7,DRD2,DUSP1,DUSP26,DUSP9,EIF4A2,ELFN1,EPHB2,ETFBKMT,FKBP1B,GPATCH2,GSKIP,HP,IL7,ITIH5,KNG1,LAMP3,LMTK2,LMTK3,LRP6,LTB4R2,LTF,MAPK8IP1,MRLN,NCKAP1L,NES,NGFR,NOS1,OAZ2,PLIN5,PPP1R14C,PPP1R1C,PRKAR2B,PRKCZ,PTPRN2,RGN,RIMBP2,RPS6KA3,SEMA4D,SERPINB7,SERPINB9,SFI1,SH2B3,SH3RF2,SLN,SOCS4,SPINK13,SPINT1,SPOCK2,SPOCK3,SRCIN1,TESC,TIMP3,TIMP4,TNNI3,TNNT2,ZGPAT |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 0.0e+00 | 0.0e+00 | 1813 | 649 | 58 | ACVR2A,ACVRL1,ADAMTS3,ALS2,ALX4,BCL2L11,C5,CAMSAP3,CEBPA,CELF4,CHRD,DSC3,EIF4A3,EOMES,EPB41L5,EXT1,FGFR1,FGFR2,FOXA1,GCM1,GRB2,HEY2,HOXA1,HS6ST1,IRX5,KPNA7,LMX1B,LRP6,MED21,MEOX1,MESP2,MMP16,MYO18B,NKD1,NKX3-1,NR5A2,NXN,PAX5,PCDH12,PCSK5,PLCD1,PLPP4,PNLDC1,RDH10,SALL2,SCEL,SCRIB,SNAI1,SOX4,SOX6,SPINT1,ST8SIA6,STK3,SULF2,TCF7,TMEM100,VASH2,XYLT1 |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 990 | 77 | ACE,ACVR2A,ADD2,AICDA,ANXA9,BCL2L11,BTN2A2,CAMK4,CARD11,CCR6,CD1D,CD34,CD3D,CD40,CD74,CD83,CD86,CEACAM1,CEBPA,CR2,CSF1R,CYP26B1,DHRS2,DLL4,EFNA2,EML1,EOMES,EPHB3,FGFR2,FZD9,HAVCR2,HLX,IL11,IL12A,IL23R,IL34,IL7,ITK,JAK2,JAM3,JUN,L3MBTL3,LTF,LY9,MEOX1,MLF1,NCKAP1L,PDE1B,PIP4K2A,PITX2,PLA2G2D,PLCL2,POLM,POU4F1,PRKCZ,PSMD9,PTGER4,PTPRZ1,RUNX3,SAMHD1,SCIN,SH2B3,SLC40A1,SOX4,SOX6,SPN,SPNS2,SPTA1,STK3,TCF7,TESC,TESPA1,TMEM176B,TSPAN2,VAV1,WDR7,ZBTB46 |
| GO_GLAND_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 437 | 45 | BCL2L11,BTRC,CDH1,CEACAM1,CEBPA,CSF1R,CYP1A1,DRD2,EAF2,EDA,EPHB3,FA2H,FGFR1,FGFR2,FGL1,FOXA1,GLI1,GPAT4,HESX1,HLX,HNF4A,HOXB13,JAK2,JUN,KALRN,LRP6,LSR,MSX2,NEURL1,NKX2-1,NKX3-1,NTN1,PITX2,PTPN3,RARB,RB1CC1,RGN,ROBO1,SCRIB,SLC29A1,SOSTDC1,SULF2,TFCP2L1,TPH1,ZNF703 |
| GO_BLOOD_VESSEL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1813 | 686 | 60 | ACVRL1,ADGRB2,ADGRB3,ANGPTL6,ANXA9,C5,CCN3,CD34,CD40,CDH2,CEACAM1,CHRNA7,COL4A3,COMP,CX3CR1,CXCR2,CYBB,DLL4,EMP2,EPHB2,EPHB3,FGF18,FGFR1,FGFR2,FLT4,GPR4,GREM1,HEY2,HOXA1,HOXB13,HS6ST1,ISM1,ITGAX,JAM3,JUN,KLF5,MIA3,MYO18B,NDNF,NFATC4,NGFR,NOTCH3,NOX5,NRP2,PLCD1,PLXDC1,PPP1R16B,PRKD2,PTGIS,PTK2,ROBO1,SCG2,SOX4,SRPK2,STAB1,TMEM100,TNNI3,TSPAN12,UNC5B,VASH2 |
| GO_CELL_KILLING | 0.0e+00 | 0.0e+00 | 1813 | 168 | 26 | AZGP1,BCL2L11,CD1D,CEACAM1,CLEC7A,CORO1A,CRTAM,EMP2,GNLY,HAVCR2,HTN3,IL12A,IL23R,ITGAM,LTF,NECTIN2,NOS2,P2RX7,RAET1G,SERPINB9,SH2D1A,SLAMF7,ULBP1,ULBP2,ULBP3,VAV1 |
| GO_MUSCLE_TISSUE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 406 | 43 | ACTN2,ADRA1A,AKAP6,AKIRIN1,BCL9,CALR,CFL2,COL19A1,CYP26B1,DLL4,EGR2,EOMES,FGFR1,FGFR2,GLI1,GREM1,HEY2,HEYL,HIVEP3,HLX,IFT20,KCNK2,KLF5,LUC7L,MAPK11,MYH14,MYH15,MYL2,MYO18B,NEURL1,NOX4,PAX5,POU4F1,RARB,RBM24,RYR1,SGCZ,SOX6,TLL2,TNNI3,TNNT2,VGLL2,XK |
| GO_LEUKOCYTE_MIGRATION | 0.0e+00 | 0.0e+00 | 1813 | 502 | 49 | ADD2,AKIRIN1,ATP1B1,ATP1B2,C5,CALR,CAMK1D,CCL26,CCN3,CCR6,CD34,CD74,CEACAM1,CORO1A,CX3CR1,CXCR2,DAPK2,DOCK8,DUSP1,ESAM,FFAR2,FPR2,GCSAML,GRB2,GREM1,HCK,IL12A,IL16,IL33,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,JAM3,LGMN,MIA3,MPP1,MYO1G,NCKAP1L,PTAFR,PTGER4,S100A9,SCG2,SELL,SELPLG,SPN,SPNS2,VAV1 |
| GO_MUSCLE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 470 | 47 | ACTN2,ADRA1A,AKAP6,ATP1B1,ATP8A2,CACNA1G,CACNA2D1,CACNB2,CAMK2B,CD38,CDK9,CHRNB2,CHRNB4,COMP,DRD2,DSC2,FKBP1B,GNAO1,GUCY1A1,HCN4,HEY2,HTR2A,KCNE5,KCNH2,KCNJ12,KCNJ5,KCNN2,MAP2K3,MAP2K6,MYH14,MYL2,NEDD4L,NMUR1,NOS1,NOS1AP,P2RY1,PTAFR,PTK2,RYR1,SCN3B,SCN4B,SCN5A,SLN,SSTR2,SULF2,TNNI3,TNNT2 |
| GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 439 | 45 | ACVR2A,BCL2L11,BIK,BMP6,CBL,CEBPA,DHH,DMRT1,EAF2,EOMES,FGFR2,FOXA1,GCM1,GDF9,GLI1,GRB2,GREB1L,HEY2,HOXB13,HS6ST1,INHBB,IRX5,LHX4,LRP6,MC2R,NKX2-1,NKX3-1,NUP210L,PCDH12,PCYT1B,PLAC1,PLCD1,PTGIS,PTK2,RAD21L1,RDH10,SLIT3,SNAI1,SPINT1,SRD5A2,STK3,TCF7,TEX11,TNFSF10,VASH2 |
| GO_MUSCLE_CONTRACTION | 0.0e+00 | 0.0e+00 | 1813 | 362 | 40 | ACTN2,ADRA1A,ATP1B1,ATP8A2,CACNA1G,CACNA2D1,CACNB2,CD38,CHRNB2,CHRNB4,COMP,DRD2,DSC2,FKBP1B,GNAO1,GUCY1A1,HCN4,HTR2A,KCNE5,KCNH2,KCNJ12,KCNJ5,KCNN2,MAP2K3,MAP2K6,MYH14,MYL2,NEDD4L,NMUR1,NOS1,NOS1AP,PTAFR,RYR1,SCN3B,SCN4B,SCN5A,SSTR2,SULF2,TNNI3,TNNT2 |
| GO_POSITIVE_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 157 | 25 | ABCB1,ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,CACNA2D1,CACNB2,DRD4,EPHB2,FGF14,HAP1,HTR3A,KCNC1,KCNE5,KCNH2,KCNJ11,KCNMB1,NOS1,NOS1AP,P2RX7,PTAFR,RGN,RGS9,TESC |
| GO_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | 0.0e+00 | 0.0e+00 | 1813 | 157 | 25 | ADRA1A,CACNA1G,CACNA1I,CACNB2,CDK5R2,CEACAM1,CHRNB2,CPLX1,CSPG5,DOC2B,DRD2,GRIK5,HTR2A,ITGAM,P2RY1,PRKCG,PTAFR,RIMS3,SCAMP5,STX1A,SYP,SYT13,SYT2,SYT5,TRIM9 |
| GO_LEUKOCYTE_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1813 | 520 | 50 | AICDA,ANXA9,BTN2A2,CAMK4,CARD11,CCR6,CD1D,CD3D,CD74,CD83,CD86,CEACAM1,CEBPA,CR2,CSF1R,CYP26B1,DHRS2,DLL4,EFNA2,EOMES,FZD9,HLX,IL11,IL12A,IL23R,IL34,IL7,ITK,JUN,L3MBTL3,LTF,LY9,NCKAP1L,PDE1B,PLA2G2D,PLCL2,POLM,POU4F1,PRKCZ,PTGER4,RUNX3,SOX4,SPN,TCF7,TESC,TESPA1,TMEM176B,TSPAN2,VAV1,ZBTB46 |
| GO_RESPONSE_TO_METAL_ION | 0.0e+00 | 0.0e+00 | 1813 | 364 | 40 | ALOX15,AOC1,BMP6,CACNA1G,CALR,CASR,CDH1,CEBPA,CHP2,CPNE4,CYBB,CYP1A1,CYP1A2,DRD2,DUSP1,FGG,HVCN1,IGFBP2,JUN,KCNC1,KCNMB1,LGMN,MT1F,NEDD4L,NFATC4,P2RX7,RYR1,RYR3,SCN5A,SLC30A10,SLC30A3,SLC40A1,SLC6A1,SYT13,SYT2,SYT5,TAT,TIGAR,TNNT2,TPH2 |
| GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | 0.0e+00 | 0.0e+00 | 1813 | 114 | 21 | ABCB1,ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,CACNA2D1,CACNB2,DRD4,EPHB2,FGF14,HAP1,HTR3A,KCNC1,KCNJ11,NOS1AP,PTAFR,RGN,RGS9,SGK2,TESC |
| GO_ANION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 294 | 35 | ABCB1,ABCC1,ANO3,ANO9,CASR,CLCA3P,CLCN4,CLIC5,CPT1A,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GLRA3,LRRC8C,LRRC8E,PTAFR,SLC12A8,SLC13A3,SLC16A10,SLC17A8,SLC1A4,SLC1A6,SLC24A4,SLC36A2,SLC36A3,SLC4A10,SLC4A5,SLC4A8,SLC6A12,SLC6A14,TTYH2,XPR1 |
| GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 56 | 15 | ATP1A3,ATP1B1,ATP1B2,CACNA1G,CACNA2D1,CACNB2,DSC2,FKBP1B,HCN4,KCNE5,KCNJ5,KCNN2,SCN3B,SCN4B,SCN5A |
| GO_POTASSIUM_ION_IMPORT_ACROSS_PLASMA_MEMBRANE | 0.0e+00 | 0.0e+00 | 1813 | 48 | 14 | ATP1A3,ATP1B1,ATP1B2,HCN2,HCN4,KCNH2,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNK9,SLC12A8 |
| GO_PHOSPHOLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 432 | 44 | ABHD5,ABHD6,ACHE,AGAP2,ALOX15,BMX,CSF1R,DDHD1,EFR3B,ENPP6,ETNPPL,FAM126B,FGFR3,FPR2,GDPD1,GPAT4,HTR2A,LIPH,LIPI,LPCAT2,NKX2-1,PCYT1B,PHOSPHO1,PI4KAP2,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,PLCD1,PLPP2,PLPP4,PLPPR4,PTK2,SBF1,SERAC1,SGPP1,SLA2,SLC44A3,SMPDL3B,SOCS4 |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1813 | 371 | 40 | AMER2,ANKRD6,APC2,ATP6V1C2,BICC1,BTRC,CDH2,CDH3,DACT3,DCDC2,DRAXIN,EDA,FGFR2,FZD9,GLI1,GPRC5B,GREM1,GSKIP,IFT20,IFT80,IGFBP2,LGR5,LRP6,MAPK8IP1,MAPK8IP2,NFATC4,NKD1,NXN,PSMD9,RNF43,SCEL,SCYL2,SHISA2,SOSTDC1,SOX4,STK3,SULF2,TCF7L1,TLE3,ZNF703 |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 810 | 66 | ACVRL1,ADGRB2,ADGRB3,AHR,ANGPTL6,ANXA9,C5,CCN3,CD34,CD40,CDH2,CEACAM1,CHRNA7,COL4A3,COMP,CX3CR1,CXCR2,CYBB,DLL4,EMP2,EPHB2,EPHB3,FGF18,FGFR1,FGFR2,FLT4,GPR4,GREM1,HEY2,HOXA1,HOXB13,HS6ST1,ISM1,ITGAX,JAM3,JUN,KLF5,MIA3,MYO18B,NDNF,NFATC4,NGFR,NKX3-1,NOTCH3,NOX5,NRP2,NXN,PCSK5,PLCD1,PLXDC1,PPP1R16B,PRKD2,PTGIS,PTK2,ROBO1,SCG2,SERPINB7,SOX4,SPINT1,SRPK2,STAB1,TMEM100,TNNI3,TSPAN12,UNC5B,VASH2 |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER | 0.0e+00 | 0.0e+00 | 1813 | 256 | 32 | ADCY4,ADGRB2,ADGRB3,ADGRE1,ADGRL1,ADGRL2,ADRA1A,CASR,CHRM4,DRD2,DRD4,FPR2,GNAL,GNAO1,GNAT2,GNAZ,GPR37,GPR37L1,GPR65,GRM7,HTR2A,IAPP,LGR5,MC2R,NOS1,NPY1R,OPRD1,OPRK1,P2RY1,PTGER4,S1PR3,SSTR2 |
| GO_ORGANIC_ACID_TRANSPORT | 0.0e+00 | 0.0e+00 | 1813 | 328 | 37 | ABCC1,ACE,AVPR1A,CASR,CEACAM1,CPLX1,CPT1A,DRD2,DRD4,GLS,GLS2,GRM7,LRRC8C,LRRC8E,MAP2K6,NOS2,P2RX7,PLA2G2D,PLA2G4A,SLC13A3,SLC16A10,SLC16A2,SLC16A5,SLC17A8,SLC1A4,SLC1A6,SLC27A6,SLC36A2,SLC36A3,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,SLCO2B1,STX1A,XK |
| GO_PROTEIN_HOMOOLIGOMERIZATION | 0.0e+00 | 0.0e+00 | 1813 | 314 | 36 | ACTN2,ASIC1,CALHM1,CD3D,CLU,CPT1A,DISP1,DPYSL3,FSD1,GBP5,GLRA3,GLS,ILDR1,KCNC1,KCNC3,KCND1,KCND2,KCNJ12,KCNV1,KCTD15,KCTD17,KCTD2,MAT1A,PRMT8,PRND,RYR1,RYR3,SAMHD1,SCUBE1,SEPTIN4,SHKBP1,SLC6A1,SLC6A4,TNFAIP1,TRPA1,VWA2 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 534 | 50 | ACTN2,ACTR3C,ADD2,ALOX15,APC2,ARHGAP40,ARHGAP44,ARHGAP6,ARHGEF10,BMERB1,CAMSAP3,CAPN6,CCL26,CFL2,CORO1A,CRACD,CSF1R,ESAM,FCHSD1,FSD1,GPR65,GRB2,HCK,IQCJ-SCHIP1,JAM3,MAP1S,MAP6,MAP6D1,MAPK15,MAPRE3,NCK2,NCKAP1L,NES,NOX4,P2RX7,PLEKHH2,PTGER4,PTK2,RHOV,RND2,S100A9,SCIN,SPTA1,SPTAN1,SPTB,STMND1,TENM1,TMEFF2,TUBB4A,WAS |
| GO_REGULATION_OF_DENDRITE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 152 | 24 | ADGRB3,ARHGAP44,BCL11A,C21orf91,CAMK1D,CAMK2B,CDKL3,CHRNB2,CPEB3,DCC,FBXO31,GRIN1,IL1RAPL1,KALRN,KNDC1,LLPH,LZTS1,MARK1,NEDD4L,NEURL1,NFATC4,RAB17,SEMA4D,SRCIN1 |
| GO_CARDIAC_MUSCLE_CONTRACTION | 0.0e+00 | 0.0e+00 | 1813 | 141 | 23 | ADRA1A,ATP1B1,CACNA1G,CACNA2D1,CACNB2,DSC2,FKBP1B,HCN4,KCNE5,KCNH2,KCNJ5,KCNN2,MAP2K3,MAP2K6,MYL2,NEDD4L,NOS1,NOS1AP,SCN3B,SCN4B,SCN5A,TNNI3,TNNT2 |
| GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1813 | 204 | 28 | ADRA1A,ALS2,ARHGAP4,ARHGAP6,ARHGEF10,ARHGEF3,CNKSR1,FGD2,FGD5,GPR4,GPR65,KALRN,MCF2L,MCF2L2,NGFR,NTN1,P2RY8,PLEKHG1,PLEKHG4B,PREX2,RASGRF1,RHOV,RND2,ROBO1,SHTN1,TNFAIP1,VAV1,WAS |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1813 | 1673 | 110 | ACER2,ACVRL1,AHR,AICDA,BACE2,BAHD1,BARX2,BCL11A,BMP6,BTRC,CALR,CD34,CD38,CDKN2A,CDYL,CEACAM1,CEBPA,CELF4,CIITA,CPEB3,CRYM,DAPK1,DLL4,DLX4,DMAP1,DMRT1,DUSP1,DUSP26,EIF4A2,EIF4A3,ENHO,EOMES,ETV3,ETV7,FGFR1,FGFR2,FOXA1,FTO,GLIS3,GREM1,HES2,HESX1,HEY2,HEYL,HIC2,HNF4A,HOXB13,IKZF5,INHBB,ITM2C,JUN,KCNK2,KDM1A,KLF5,LIN28A,MALRD1,MALSU1,MAPK10,METTL14,MSX2,NCK2,NEDD4L,NFATC4,NFE2L3,NKX2-1,NKX3-1,NKX6-1,NOSTRIN,NOTCH3,NPAS1,NR2C1,NR2F1,NR6A1,ORMDL3,PAX5,PAX9,POU4F1,PRAME,PRDM6,PTGIS,RARB,RBM24,RGN,RITA1,RORB,RUNX3,SALL2,SAMD4B,SEMA4D,SFMBT2,SLA2,SLC18A2,SLC30A10,SNAI1,SNAI3,SOX6,SP5,SPDEF,TCF7,TFCP2L1,TLE3,TMEFF2,UBA3,UBE2D1,ZGPAT,ZNF253,ZNF431,ZNF703,ZNF93,ZNFX1 |
| GO_ACTIN_FILAMENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1813 | 393 | 41 | ACTN2,ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP6,ARHGEF10,CCL26,CFL2,CORO1A,CRACD,DPYSL3,EMP2,ENAH,ESAM,FCHSD1,FSCN3,GPR65,GRB2,HCK,JAK2,NCK2,NCKAP1L,NOX4,PDLIM3,PLEKHH2,PLS1,PTGER4,RHOV,RND2,SAMD14,SCIN,SHTN1,SPTA1,SPTAN1,SPTB,TENM1,TMEFF2,TNFAIP1,WAS,WASF3 |
| GO_CELL_SUBSTRATE_ADHESION | 0.0e+00 | 0.0e+00 | 1813 | 348 | 38 | ACER2,ACTN2,ACVRL1,ALOX15,ARHGAP6,BCL2L11,CALR,CAMSAP3,CD34,CDKN2A,COL19A1,COL5A3,CORO1A,CSPG5,EDA,EMP2,EPB41L5,EPDR1,EPHB3,FGG,GREM1,ITGA6,ITGAL,ITGB7,JAK2,JAM3,LYPD5,MYO1G,NDNF,OTOA,POSTN,PRKCZ,PTK2,RADIL,SPOCK2,SRCIN1,TESK2,VWA2 |
| GO_BONE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1813 | 219 | 29 | ANXA9,BMP6,COMP,CSGALNACT1,CYP26B1,FGF18,FGFR2,FGFR3,GREM1,IFT80,LRP6,LTF,MMP13,MMP16,MSX2,PHOSPHO1,PIP4K2A,PITX2,PTGER4,RARB,RGN,RYR1,SEMA4D,SH2B3,SP5,SPNS2,SULF2,VWA2,XYLT1 |
| GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 0.0e+00 | 1813 | 167 | 25 | AMIGO1,CDH1,CDH15,CDH2,CDH3,CDHR3,CEACAM1,CLSTN3,DSC2,DSC3,DSG3,ESAM,IGSF11,IGSF9,NECTIN2,PCDH10,PCDH12,PCDH20,PCDHA10,PCDHA4,PCDHA5,PCDHGA3,ROBO1,SDK2,TRO |
| GO_ACTIN_FILAMENT_BASED_MOVEMENT | 0.0e+00 | 1.0e-07 | 1813 | 143 | 23 | ACTN2,CACNA1G,CACNA2D1,CACNB2,DSC2,EMP2,EPB41L5,HCN4,KCNE5,KCNH2,KCNJ5,KCNN2,MYH14,MYL2,NEDD4L,NOS1AP,SCN3B,SCN4B,SCN5A,SHTN1,TNNI3,TNNT2,WAS |
| GO_CHLORIDE_TRANSPORT | 0.0e+00 | 1.0e-07 | 1813 | 109 | 20 | ABCB1,ANO3,ANO9,CASR,CLCA3P,CLCN4,CLIC5,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GLRA3,NMUR1,PTAFR,SLC12A8,SLC1A4,SLC4A10,TTYH2 |
| GO_GAMETE_GENERATION | 0.0e+00 | 1.0e-07 | 1813 | 698 | 59 | ACE,ACVR2A,ADAM28,ADCYAP1R1,AZIN2,BCL2L11,CALR,CCR6,CDYL,CELF4,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,GDF9,GLI1,HOOK1,IFT20,INHBB,JAM3,LGR5,LIN28A,LRGUK,METTL14,NECTIN2,NEURL1,NR6A1,NUP210L,PAEP,PARP11,PAX5,PCYT1B,PIWIL3,PTCHD3,RAD21L1,RGN,SBF1,SEPTIN4,SEPTIN6,SPANXA1,SPATA32,SPEF2,SSTR2,STRBP,TAF1L,TBPL1,TDRD7,TDRKH,TDRP,TESK2,TEX11,TSNAX,TSSK1B |
| GO_REGULATION_OF_PEPTIDE_HORMONE_SECRETION | 0.0e+00 | 1.0e-07 | 1813 | 207 | 28 | ABCC8,ACVR1C,BMP8A,CACNA2D2,CASR,CCN3,CD38,CPT1A,DOC2B,DRD2,ENHO,FFAR2,FGG,FKBP1B,HNF4A,ILDR1,INHBB,JAK2,KALRN,KCNJ11,NKX6-1,NOS2,PSMD9,SIRT4,SOX4,STX1A,SYBU,VSNL1 |
| GO_DENDRITE_MORPHOGENESIS | 0.0e+00 | 1.0e-07 | 1813 | 144 | 23 | ADGRB3,ARHGAP44,CAMK2B,CDKL3,CHRNA7,CHRNB2,DCDC2,DCLK1,EPHB2,EPHB3,FBXO31,GRIN1,IL1RAPL1,KALRN,KNDC1,LZTS1,MAP6,MAPK8IP2,NEDD4L,NFATC4,PREX2,SEMA4D,SRCIN1 |
| GO_ACTIN_MEDIATED_CELL_CONTRACTION | 0.0e+00 | 1.0e-07 | 1813 | 121 | 21 | ACTN2,CACNA1G,CACNA2D1,CACNB2,DSC2,EMP2,EPB41L5,HCN4,KCNE5,KCNH2,KCNJ5,KCNN2,MYL2,NEDD4L,NOS1AP,SCN3B,SCN4B,SCN5A,SHTN1,TNNI3,TNNT2 |
| GO_CALCIUM_MEDIATED_SIGNALING | 0.0e+00 | 1.0e-07 | 1813 | 221 | 29 | ADGRB2,ADGRL1,AKAP6,ATP1B1,AVPR1A,CCR6,CCRL2,CD22,CHP2,CX3CR1,CXCR2,FKBP1B,FPR2,GPR143,GRIN1,HAP1,KSR2,MCTP2,NCALD,NFATC4,NMUR1,NOS1,NR5A2,P2RX7,RGN,SAMD14,SLA2,TMEM100,TNNI3 |
| GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1813 | 351 | 38 | ACTN2,ACTR3C,ADD2,ALOX15,APC2,ARHGAP40,ARHGAP6,ARHGEF10,BMERB1,CAMSAP3,CCL26,CFL2,CHRNA7,CLU,CORO1A,CRACD,ESAM,FCHSD1,GPR65,GRB2,HCK,IAPP,MAP1S,MAP6D1,MAPRE3,NCK2,NCKAP1L,NOX4,PLEKHH2,PTGER4,SCIN,SPTA1,SPTAN1,SPTB,TENM1,TMEFF2,TUBB4A,WAS |
| GO_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS | 0.0e+00 | 1.0e-07 | 1813 | 221 | 29 | ARL6,ATP8A2,CABP1,CACNB2,CDH3,CHRNB2,CLIC5,CNGA1,CNGB1,CRYBB3,DLL4,GJA3,GNAT2,GPR143,GUCA1B,GUCA1C,IRX5,OAT,OLFM2,POU4F3,PRCD,RDH10,RDH12,RGS9,RORB,SEMA5B,SLC4A10,TIMP3,USH2A |
| GO_GLYCEROLIPID_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1813 | 414 | 42 | ABHD5,ABHD6,ACHE,AGAP2,AGMO,ALOX15,BMX,CNEP1R1,CPT1A,CSF1R,DDHD1,EFR3B,ENPP6,ETNPPL,FABP6,FAM126B,FGF21,FPR2,GDPD1,GPAT4,HTR2A,LIPH,LIPI,LPCAT2,PCYT1B,PHOSPHO1,PI4KAP2,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,PLIN5,RGN,SBF1,SERAC1,SLA2,SLC44A3,SOCS4 |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 1813 | 791 | 64 | ALOX15,BTRC,CAMK2B,CBL,CCL26,CCR6,CCRL2,CD40,CD70,CD74,CD86,CEACAM1,CEBPA,CIITA,CRLF1,CSF1R,CX3CR1,CXCR2,EDA,GHR,GRB2,GREM2,HCK,HLA-DPB1,IFNLR1,IL11,IL12A,IL16,IL17RD,IL19,IL1R2,IL23R,IL2RB,IL33,IL34,IL3RA,IL7,ITGAM,ITGAX,JAK2,MTAP,NCAM1,NOS2,OAS1,OASL,OPRD1,PALM3,PELI1,PSMD9,PTAFR,PTPRZ1,ROBO1,SAMHD1,SCRIB,SH2B3,SLIT3,STAT4,STX1A,TNFRSF19,TNFRSF8,TNFSF15,TXK,UGCG,VAV1 |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 0.0e+00 | 1.0e-07 | 1813 | 650 | 56 | ADA2,AOC1,ARHGAP9,CAMK4,CBL,CD74,CEACAM1,CEBPA,CHRNB4,CLU,CST7,CXCR2,CYBB,DHRS2,DYNLL1,FCN1,FPR2,FRMPD3,GCA,GOLGA7,HAVCR2,HP,HUWE1,HVCN1,IL33,IST1,ITGAL,ITGAM,ITGAX,JAK2,JUN,LAIR1,LILRA2,LRFN5,LTF,MAGT1,MGAM,NCKAP1L,NECTIN2,NFASC,ORMDL3,PIGR,PTAFR,PTPRN2,PYGL,RAB37,RAB44,RAB9B,S100A9,SELL,SIGLEC14,SPTAN1,TAFA3,TLR7,TMC6,TMEM30A |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 1.0e-07 | 1813 | 400 | 41 | BMP6,BTRC,CARD11,CD1D,CD209,CLEC7A,CRTAM,FCN1,FFAR2,FGG,FPR2,GBP5,HAVCR2,HCK,ICAM2,IL12A,ITGAM,KLK7,LGMN,LILRA2,LTF,MAP2K6,MUC20,NECTIN2,PELI1,PIK3AP1,PSMD9,RAET1G,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SH2D1A,SMPDL3B,TLR10,TLR5,TLR7,TXK,UBE2D1,VAV1 |
| GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 1.0e-07 | 1813 | 237 | 30 | ADRA1A,ALS2,ARHGAP44,ARHGEF10,ARHGEF3,CADM4,CBL,CYTH4,EPHB2,FGD2,FGD5,GPR4,GPR65,GRB2,JAK2,KALRN,MCF2L,MCF2L2,P2RY8,PLEKHG1,PLEKHG4B,PREX2,PSD,PSD2,RALGPS1,RASGRF1,ROBO1,SGSM3,TNFAIP1,VAV1 |
| GO_RENAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 1.0e-07 | 1813 | 294 | 34 | ACE,AHI1,BCL2L11,BMP6,CD34,COL4A3,CRLF1,CXCR2,CYP26B1,FGFR1,FGFR2,FRAS1,GCNT3,GCNT4,GPR4,GREB1L,GREM1,HEYL,IFT20,ITGA6,KIF26B,LGR5,LIN28A,MAGI2,NKX3-1,NOTCH3,PCSK5,PODXL,RARB,RDH10,RGN,SERPINB7,SOX4,SULF2 |
| GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 1813 | 500 | 47 | BTN2A2,BTNL9,BTRC,CARD11,CD209,CD22,CD38,CD3D,CD40,CEACAM1,CR2,CYFIP2,ELMO2,FCN1,FFAR2,FPR2,FYB2,GCSAML,GRB2,HCK,HHLA2,HLA-DPB1,ICAM2,ITK,JUN,LILRA2,MAPK10,MUC20,MYO10,MYO1G,NCKAP1L,NECTIN2,PAX5,PIGR,PLCL2,PLPP4,PRKD2,PSMD9,PTK2,RAB29,SLA2,TESPA1,THEMIS2,TRAC,TXK,VAV1,WAS |
| GO_REGULATION_OF_CELL_ACTIVATION | 0.0e+00 | 1.0e-07 | 1813 | 619 | 54 | AHR,BTN2A2,CAMK4,CARD11,CD1D,CD209,CD22,CD38,CD40,CD6,CD70,CD74,CD83,CD86,CEACAM1,CEBPA,CHRNB2,CLEC7A,CORO1A,CST7,CYP26B1,DOCK8,FGG,FGL1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL33,IL7,ITGAM,JAK2,LILRA2,LRFN5,MAPK8IP1,NCK2,NCKAP1L,NECTIN2,PELI1,PLA2G2D,PRKCZ,PTAFR,RUNX3,SH2B3,SLA2,SPN,SPTA1,TAFA3,TESPA1,VAV1 |
| GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 0.0e+00 | 1.0e-07 | 1813 | 225 | 29 | AHR,BTN2A2,CARD11,CD1D,CD209,CD22,CD38,CD40,CD6,CD70,CD74,CD86,CHRNB2,CORO1A,GREM1,HAVCR2,HHLA2,HLA-DPB1,IGFBP2,IL12A,IL23R,IL7,MAPK8IP1,NCK2,NCKAP1L,PELI1,PLA2G2D,SPN,SPTA1 |
| GO_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL | 0.0e+00 | 1.0e-07 | 1813 | 37 | 12 | CACNA1G,CACNA1I,CACNA2D1,CACNB2,HCN2,HCN4,KCNH2,PTPN3,SCN3A,SCN3B,SCN4B,SCN5A |
| GO_MEMBRANE_DEPOLARIZATION | 0.0e+00 | 1.0e-07 | 1813 | 91 | 18 | CACNA1G,CACNA1I,CACNA2D1,CACNB2,CHRNB2,FZD9,HCN2,HCN4,JUN,KCNH2,NEDD4L,P2RX7,PRKCZ,PTPN3,SCN3A,SCN3B,SCN4B,SCN5A |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1813 | 1301 | 90 | ACE,ACER2,ACER3,ADA2,ADHFE1,AGAP2,AICDA,AMN1,ANXA9,APC2,ASRGL1,AZIN2,BACE2,BTRC,CBL,CDH1,CEACAM1,CEBPA,CLEC16A,CLU,CPVL,CRYM,CSPG5,DNAJC18,FBXL7,FBXO31,FBXO44,FMOD,GAD1,GGTLC3,GLDC,GLS,GLS2,GPC2,HAL,HUWE1,HYAL4,HYKK,IL33,KCTD17,KCTD2,LAMP3,LGMN,MAT1A,MYLIP,NCCRP1,NEDD4L,NKD1,NOS1,NOS2,OAT,OAZ2,OGA,P2RX7,PADI4,PDE10A,PDE4C,PELI1,PRELP,PRKCG,PSMD9,PTK2,PTPN3,RGN,RNF125,RNF216,RNF43,SAMHD1,SDS,SEC22B,SGSM3,SGTB,SH3RF2,SMPDL3B,SOCS4,SPSB4,STT3B,TAT,TIMP3,TIMP4,TNFAIP1,TRIM9,UBAP1,UBE2D1,UBE2W,UBE3D,UBE4A,USP35,USP43,VCAN |
| GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1813 | 286 | 33 | CD34,CLEC7A,CLU,CX3CR1,CYB5R4,CYBB,CYP1A1,CYP1A2,FPR2,GLS2,GRB2,GRIN1,HBA1,HBE1,HBG2,HP,ITGAM,JAK2,LPO,NOS1,NOS1AP,NOS2,NOX4,NOX5,P2RX7,PLIN5,PTGIS,PXDNL,RGN,SLC18A2,SLC30A10,TIGAR,VAV1 |
| GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | 0.0e+00 | 1.0e-07 | 1813 | 216 | 28 | ALOX15,AOC1,BMP6,CALR,CDH1,CEBPA,CHP2,CPNE4,CYBB,CYP1A1,CYP1A2,EIF4A3,GUCY1B1,HVCN1,JUN,LGMN,MT1F,NFATC4,RYR1,RYR3,SCN5A,SLC30A10,SLC40A1,SYT13,SYT2,SYT5,TIGAR,TPH2 |
| GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION | 0.0e+00 | 1.0e-07 | 1813 | 394 | 40 | BTN2A2,CARD11,CD1D,CD209,CD38,CD40,CD6,CD70,CD74,CD83,CD86,CEBPA,CHRNB2,CLEC7A,CORO1A,DOCK8,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL33,IL7,ITGAM,JAK2,LILRA2,NCK2,NCKAP1L,NECTIN2,PELI1,PRKCZ,PTAFR,RUNX3,SPTA1,TAFA3,TESPA1,VAV1 |
| GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 0.0e+00 | 1.0e-07 | 1813 | 258 | 31 | ACE,ADRA1A,AFAP1L2,BMP6,CADM4,CBL,CD40,CD74,CNTN1,CRLF1,CSF1R,DOK7,FGFR3,GHR,GPRC5B,GREM1,HTR2A,IL11,IL12A,IL23R,IL7,JAK2,NCK2,NEURL1,NOX4,PRKCZ,SEMA4D,SH2B3,SOCS4,SRCIN1,ZGPAT |
| GO_SYNAPTIC_VESICLE_EXOCYTOSIS | 0.0e+00 | 2.0e-07 | 1813 | 116 | 20 | ADRA1A,CACNB2,CHRNB2,CPLX1,CSPG5,DOC2B,DRD2,GRIK5,HTR2A,P2RX7,P2RY1,PRKCG,RIMS3,SCRIB,STX11,STX1A,SYP,SYT2,SYT5,TRIM9 |
| GO_REGULATION_OF_T_CELL_ACTIVATION | 0.0e+00 | 2.0e-07 | 1813 | 318 | 35 | BTN2A2,CAMK4,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CEACAM1,CORO1A,CYP26B1,DOCK8,FGL1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,MAPK8IP1,NCK2,NCKAP1L,PELI1,PLA2G2D,PRKCZ,RUNX3,SPN,SPTA1,TESPA1,VAV1 |
| GO_STRIATED_MUSCLE_CONTRACTION | 0.0e+00 | 2.0e-07 | 1813 | 177 | 25 | ADRA1A,ATP1B1,ATP8A2,CACNA1G,CACNA2D1,CACNB2,DSC2,FKBP1B,HCN4,KCNE5,KCNH2,KCNJ5,KCNN2,MAP2K3,MAP2K6,MYH14,MYL2,NEDD4L,NOS1,NOS1AP,SCN3B,SCN4B,SCN5A,TNNI3,TNNT2 |
| GO_CONNECTIVE_TISSUE_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1813 | 274 | 32 | ACVRL1,ANXA9,BARX2,BMP6,BMP8A,CASR,CCN3,CD34,COMP,CSGALNACT1,DYRK1B,EBF2,FGF18,FGFR1,FGFR3,FOXA1,FTO,GDF6,GPR4,GREM1,IFT80,LRP6,MMP13,MSX2,RARB,RUNX3,SCIN,SERPINB7,SNAI1,SOX6,SULF2,VWA2 |
| GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 2.0e-07 | 1813 | 204 | 27 | ABCB1,ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,AZIN2,CACNA2D1,CACNB2,DRD4,EPHB2,FGF14,FGF21,HAP1,HTR3A,KCNC1,KCNE5,KCNH2,KCNJ11,KCNMB1,NOS1,NOS1AP,P2RX7,PTAFR,RGN,RGS9,TESC |
| GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 0.0e+00 | 2.0e-07 | 1813 | 140 | 22 | CARD11,CD1D,CD209,CD38,CD40,CD6,CD70,CD74,CD86,CHRNB2,CORO1A,HAVCR2,HHLA2,HLA-DPB1,IGFBP2,IL12A,IL23R,IL7,NCK2,NCKAP1L,PELI1,SPTA1 |
| GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | 0.0e+00 | 2.0e-07 | 1813 | 140 | 22 | ADRA1A,ASIC1,CACNB2,CHRNB2,CHRNB4,CPLX1,CSPG5,DRD2,DRD4,GRIK5,HTR2A,MCTP2,NOS1,P2RX7,P2RY1,PRKCG,RAB3B,RIMS3,SLC6A1,SLC6A4,STX1A,SYP |
| GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 0.0e+00 | 2.0e-07 | 1813 | 74 | 16 | ATP1B1,CACNA1G,CACNA2D1,CACNB2,DSC2,HCN2,HCN4,KCNE5,KCNH2,KCNJ5,KCNN2,NEDD4L,NOS1AP,SCN3B,SCN4B,SCN5A |
| GO_DEPHOSPHORYLATION | 0.0e+00 | 2.0e-07 | 1813 | 479 | 45 | ARMT1,BTRC,CAMSAP3,CDC14A,CHP2,CILP2,CNEP1R1,CTTNBP2NL,DRD2,DUSP1,DUSP26,DUSP9,ELFN1,FKBP1B,GPATCH2,JAK2,LMTK2,LMTK3,MAGI2,NCKAP1L,PHOSPHO1,PLPP2,PLPP4,PLPPR4,PPM1J,PPM1L,PPP1R14C,PPP1R16B,PPP1R1C,PPP1R42,PPP2R2C,PPP6C,PTPN3,PTPRN2,PTPRZ1,RGN,RIMBP2,SBF1,SEMA4D,SFI1,SGPP1,SH3RF2,SYMPK,TIGAR,VRK3 |
| GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1813 | 320 | 35 | ABHD5,ABHD6,ACHE,AGAP2,ALOX15,BMX,CSF1R,DDHD1,EFR3B,ENPP6,ETNPPL,FAM126B,FPR2,GDPD1,GPAT4,HTR2A,LIPH,LIPI,LPCAT2,PCYT1B,PHOSPHO1,PI4KAP2,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,SBF1,SERAC1,SLA2,SLC44A3,SOCS4 |
| GO_NEGATIVE_REGULATION_OF_GROWTH | 0.0e+00 | 2.0e-07 | 1813 | 247 | 30 | ACVRL1,ARHGAP4,BCL11A,CCN3,CDKL3,CDKN2A,DACT3,DCC,DRAXIN,EAF2,FGFR3,GDF9,GNG4,GREM1,HNF4A,KCNK2,LGMN,MAPK11,MT1F,MYL2,NKD1,NTN1,PTK2,SEMA4D,SEMA7A,SLC6A4,SLIT3,STK3,TLL2,TMPRSS4 |
| GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | 0.0e+00 | 2.0e-07 | 1813 | 219 | 28 | BTN2A2,CARD11,CD1D,CD209,CD6,CD70,CD74,CD83,CD86,CORO1A,DOCK8,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,NCK2,NCKAP1L,PRKCZ,PTAFR,RUNX3,SPTA1,TESPA1,VAV1 |
| GO_PROTEIN_AUTOPHOSPHORYLATION | 0.0e+00 | 2.0e-07 | 1813 | 233 | 29 | ACE,BMX,CAMK2B,CAMK4,CSF1R,DAPK1,DAPK2,DYRK1B,EPHB3,FGFR1,FGFR2,FGFR3,FGFR4,FLT4,GFRA2,GREM1,HCK,ITK,JAK2,JUN,LMTK2,MAP4K1,MAPK15,MKNK1,PRKCG,PRKD2,PTK2,STK26,TXK |
| GO_AMMONIUM_ION_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1813 | 206 | 27 | ACER2,ACER3,ACHE,AZIN2,CHRNB2,CPT1A,CPT1C,DDC,DRD2,DRD4,ENPP6,GPAT4,GPR37,ITGAM,LPCAT2,PCYT1B,PDE1B,PHOSPHO1,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,SGPP1,SLC44A3,SMPDL3B,TPH1,TPH2 |
| GO_EAR_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1813 | 220 | 28 | AHI1,ATOH1,ATP8A2,BCL2L11,CEBPA,CHRNA10,EPHB2,ESRRB,FGFR1,FGFR2,FREM2,GABRB2,HESX1,HEY2,HOXA1,IFT20,KCNK2,KCNQ4,LGR5,MYCL,NTN1,PLPPR4,POU4F3,RDH10,SCRIB,SLC17A8,SLC25A27,USH2A |
| GO_GLIOGENESIS | 0.0e+00 | 2.0e-07 | 1813 | 292 | 33 | ADAM22,ARHGEF10,B4GALT5,BACE2,BMERB1,CDH2,CDK5R2,CLU,CSF1R,CSPG5,CX3CR1,EGR2,FA2H,FPR2,GCM1,GPR37L1,IL33,IL34,LIN28A,METTL14,MYRF,NKX2-1,NKX6-1,P2RY1,PLP1,PTPRZ1,SCRIB,SH3TC2,SOX4,SOX6,SPINT1,TSPAN2,WASF3 |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 2.0e-07 | 1813 | 353 | 37 | ACSM2A,ACSM3,AKR1D1,ALOX15,AVPR1A,CD74,CEACAM1,CSPG5,CYP1A1,CYP1A2,CYP27A1,CYP39A1,CYP46A1,DHRS9,ELOVL4,FA2H,FADS6,FGFR4,GAD1,GGTLC3,GLS,GLS2,MALRD1,MTAP,NOXRED1,OAT,OSBPL6,PLA2G4A,PLP1,PTGIS,RBP1,RDH10,RGN,RIMKLA,RIMKLB,SDS,VCAN |
| GO_CELL_JUNCTION_ORGANIZATION | 0.0e+00 | 2.0e-07 | 1813 | 293 | 33 | ACE,ACTN2,ACVRL1,ARHGAP6,BMP6,CADM2,CAMSAP3,CDH1,CDH15,CDH2,CDH3,CDHR3,CSF1R,EPB41L5,ESAM,GPBAR1,GREM1,GRHL1,ITGA6,JAM3,LSR,NECTIN2,NFASC,OCLN,PARD6G,PTK2,SDK2,SNAI1,TESK2,TJP1,UGT8,VMP1,ZNF703 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1813 | 587 | 51 | BTN2A2,C1QL4,CADM4,CAMSAP3,CBL,CDKN2A,CEACAM1,CEBPA,CHRNA10,DRD2,DUSP1,DUSP26,DUSP9,DYNLL1,ELFN1,EPHB2,FKBP1B,GFRA2,GPATCH2,GREM1,GSKIP,JUN,KIRREL2,KLHL31,LDLRAD4,LMTK2,LMTK3,LRP6,MAPK8IP1,NCK2,NCKAP1L,NDRG2,P2RX7,PPP1R14C,PPP1R16B,PPP1R1C,PRKAR2B,PRKCZ,RGN,RIMBP2,SEMA4D,SFI1,SH2B3,SH3RF2,SOCS4,SRCIN1,TESC,TIGAR,TIMP3,VRK3,ZGPAT |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 2.0e-07 | 1813 | 622 | 53 | AHI1,AP3B2,ARL6,BICDL1,BICDL2,CBL,CDH2,CDH3,CEP19,CEP83,CLMN,CNIH2,DYNLL1,ESYT3,F5,GEM,GPR143,HAP1,IFT20,KIF13A,KIF5A,KIF5C,MAGI2,MAP1S,MAP6,MAPK15,MARK1,MFN1,NECTIN2,NTN1,PDZD8,PLIN5,PPP6C,PRKAR2B,PRKCZ,PTK2,RAB17,RAB3B,RAD21L1,SCFD1,SCRIB,SEC22B,SFI1,SLC2A4,SLC4A5,SLIT1,STX11,STX12,STX1A,STX6,SYBU,SYN3,TUBB4A |
| GO_CHEMICAL_SYNAPTIC_TRANSMISSION_POSTSYNAPTIC | 0.0e+00 | 3.0e-07 | 1813 | 109 | 19 | CELF4,CHRNA10,CHRNA7,CHRNB2,CHRNB4,DRD2,DRD4,EIF4A3,GLRA3,GRIK5,GRIN1,IGSF11,INSYN1,MAPK8IP2,NRXN1,P2RX7,PRKCZ,SLC29A1,STX1A |
| GO_MUSCLE_ORGAN_DEVELOPMENT | 0.0e+00 | 3.0e-07 | 1813 | 407 | 40 | ACHE,AKAP6,AKIRIN1,ALX4,BCL9,BORCS8-MEF2B,CFL2,CHODL,COL19A1,CYP26B1,DISP1,DLL4,EGR2,EOMES,FGFR1,FGFR2,GLI1,GREM1,HEY2,HEYL,HIVEP3,HLX,KCNK2,KLF5,LUC7L,MAPK11,MYH14,MYH15,MYL2,NEURL1,PAX5,POU4F1,RBM24,RYR1,SOX6,TLL2,TNNI3,TNNT2,VGLL2,XK |
| GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 3.0e-07 | 1813 | 184 | 25 | ARHGAP4,ARHGAP44,BCL11A,CD38,CDKL3,CRMP1,DCC,DPYSL3,DRAXIN,EPHB2,ITM2C,LINGO1,MYLIP,NFATC4,NGFR,NR2F1,NTN1,PTK2,RAB29,RAP1GAP,RGMA,RTN4RL2,SEMA4D,SEMA7A,TBC1D30 |
| GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 0.0e+00 | 3.0e-07 | 1813 | 211 | 27 | ADRA1A,ALOX15,CASR,CCL26,CD74,CHRNA7,CSF1R,DRD2,FGF18,FGF21,FGFR2,FGFR3,FGFR4,FGG,FLT4,FPR2,GAREM1,HAVCR2,HTR2A,JUN,NOX4,P2RY1,PRKCZ,PRKD2,SCIMP,SEMA7A,SLC30A10 |
| GO_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1813 | 89 | 17 | ADCY4,CASR,CHRM4,DRD2,DRD4,FPR2,GNAL,GNAZ,GPR37,GPR37L1,GRM7,NPY1R,OPRD1,OPRK1,P2RY1,S1PR3,SSTR2 |
| GO_NEGATIVE_REGULATION_OF_PEPTIDE_HORMONE_SECRETION | 0.0e+00 | 4.0e-07 | 1813 | 42 | 12 | ACVR1C,BMP8A,CCN3,DRD2,ENHO,FKBP1B,INHBB,KALRN,KCNJ11,PSMD9,SIRT4,VSNL1 |
| GO_OSSIFICATION | 0.0e+00 | 4.0e-07 | 1813 | 396 | 39 | ACHE,ACVR2A,ALOX15,BMP2K,BMP6,BMP8A,CASR,CEBPA,CHRD,CLEC11A,CLEC3A,COMP,CSGALNACT1,DHH,EGR2,EXT1,FGF18,FGFR2,FGFR3,FZD9,GLI1,GREM1,IFT80,LTF,MMP13,MMP16,MSX2,P2RX7,PHOSPHO1,PTGER4,PTK2,RORB,RYR1,SEMA4D,SEMA7A,SNAI1,TPH1,VCAN,XYLT1 |
| GO_REGULATION_OF_SYNAPTIC_VESICLE_CYCLE | 0.0e+00 | 4.0e-07 | 1813 | 112 | 19 | ADRA1A,CACNB2,CDH2,CHRNB2,CPLX1,CSPG5,DRD2,FGF14,GRIK5,HTR2A,MAGI2,NRXN1,P2RY1,PRKCG,RAB3B,RIMS3,SLC2A4,STX1A,SYP |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1813 | 348 | 36 | ACVR1C,ACVR2A,ACVRL1,BMP6,BMP8A,BTBD11,CBL,CCN3,CGN,CHRD,COMP,DMRT1,FMOD,GDF6,GDF9,GREM1,GREM2,HNF4A,IGSF1,INHBB,INHBC,JUN,LDLRAD4,MAGI2,MSX2,NEO1,NKX2-1,PPM1L,PRKCZ,PTK2,RGMA,SOSTDC1,TDGF1P3,TMEM100,UBE2D1,ZNF703 |
| GO_REGULATION_OF_HEART_RATE | 0.0e+00 | 5.0e-07 | 1813 | 101 | 18 | ADRA1A,AVPR1A,CACNA1G,CACNA2D1,CACNB2,DRD2,DSC2,FKBP1B,HCN4,HEY2,IRX5,KCNE5,KCNH2,KCNJ5,NOS1AP,SCN3B,SCN4B,SCN5A |
| GO_PATTERN_SPECIFICATION_PROCESS | 0.0e+00 | 5.0e-07 | 1813 | 446 | 42 | ACVR2A,AHI1,ALX4,AP1B1,APC2,ARL6,BICC1,CFAP53,CHRD,CYP26B1,DISP1,DLL4,DNAI1,EGR2,EOMES,EPB41L5,FGFR1,FGFR2,FOXA1,GLI1,GREM1,GREM2,HES2,HEY2,HEYL,ITGAM,LMX1B,LRP6,MEOX1,MESP2,MSX2,NKD1,NKX2-1,NKX3-1,NKX6-1,NRP2,PCSK5,PITX2,ROBO1,SNAI1,SOSTDC1,TDGF1P3 |
| GO_REGULATION_OF_INSULIN_SECRETION | 0.0e+00 | 5.0e-07 | 1813 | 175 | 24 | ABCC8,ACVR1C,BMP8A,CACNA2D2,CASR,CCN3,CD38,CPT1A,DOC2B,DRD2,ENHO,FKBP1B,HNF4A,INHBB,JAK2,KCNJ11,NKX6-1,NOS2,PSMD9,SIRT4,SOX4,STX1A,SYBU,VSNL1 |
| GO_REGULATION_OF_CHEMOTAXIS | 0.0e+00 | 5.0e-07 | 1813 | 216 | 27 | AKIRIN1,C5,CALR,CAMK1D,CASR,CCL26,CCN3,CCR6,CD74,CXCR2,DAPK2,DUSP1,FGF18,FGFR1,FPR2,GREM1,IL12A,IL16,JAM3,LGMN,MPP1,NCKAP1L,PRKD2,ROBO1,SCG2,SEMA4D,SEMA7A |
| GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 0.0e+00 | 5.0e-07 | 1813 | 710 | 57 | ADA2,AICDA,AOC1,ARHGAP9,CBL,CCR6,CD40,CD86,CEACAM1,CHRNB4,CORO1A,CXCR2,CYBB,DYNLL1,EOMES,FCN1,FPR2,FRMPD3,GCA,GOLGA7,HAVCR2,HLX,HP,HUWE1,HVCN1,IL23R,IL33,IST1,ITGAL,ITGAM,ITGAX,LAIR1,LILRA2,LTF,LY9,MAGT1,MGAM,NCKAP1L,NFASC,ORMDL3,PIGR,PLCL2,PRKCZ,PTAFR,PTGER4,PTPRN2,PYGL,RAB37,RAB44,RAB9B,S100A9,SELL,SIGLEC14,SPN,SPTAN1,TMC6,TMEM30A |
| GO_NEGATIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 6.0e-07 | 1813 | 534 | 47 | ACTN2,ACVR1C,ANO9,ASIC1,BMP8A,BTN2A2,CABP1,CCN3,CD22,CD34,CD74,CEACAM1,CNIH2,CORO1A,CTTNBP2NL,DRD2,DRD4,ENHO,EPHB2,FKBP1B,FZD9,GEM,GNAO1,GRM7,HTR2A,IL11,IL1R2,IL1RAPL1,IL33,INHBB,KALRN,KCNE5,KCNH2,KCNJ11,MRLN,NEDD4L,NOS1,OAZ2,P2RY1,PSMD9,PTGER4,SCAMP5,SIRT4,SLN,SRCIN1,TRIM9,VSNL1 |
| GO_CANONICAL_WNT_SIGNALING_PATHWAY | 0.0e+00 | 6.0e-07 | 1813 | 337 | 35 | AMER2,ANKRD6,APC2,BCL9,BICC1,BTRC,CDH2,CDH3,DACT3,DRAXIN,EDA,FGFR2,FZD9,GLI1,GPRC5B,GREM1,GSKIP,IFT20,IGFBP2,LGR5,LRP6,MAPK8IP1,MAPK8IP2,NKD1,PSMD9,SCEL,SCYL2,SOSTDC1,SOX4,STK3,SULF2,TCF7,TCF7L1,TLE3,ZNF703 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 6.0e-07 | 1813 | 337 | 35 | ARHGAP4,BCL11A,BMERB1,BRINP1,CALR,CD38,CDKL3,CRMP1,DCC,DISP3,DPYSL3,DRAXIN,EPHB2,GPR37L1,ITM2C,LIN28A,LINGO1,LTF,MYLIP,NFATC4,NGFR,NKX6-1,NOTCH3,NR2F1,NTN1,PAEP,POSTN,PTK2,RAB29,RGMA,RTN4RL2,S1PR3,SEMA4D,SEMA7A,SLC6A4 |
| GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | 0.0e+00 | 7.0e-07 | 1813 | 205 | 26 | ACTN2,ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP6,CCL26,CFL2,CORO1A,CRACD,ENAH,ESAM,FCHSD1,GRB2,HCK,JAK2,NCK2,NCKAP1L,PLEKHH2,SCIN,SPTA1,SPTAN1,SPTB,TENM1,WAS,WASF3 |
| GO_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 7.0e-07 | 1813 | 233 | 28 | ACSM2A,ACSM3,AKR1D1,ALOX15,AVPR1A,CD74,CEACAM1,CSPG5,CYP1A1,CYP1A2,CYP27A1,CYP39A1,CYP46A1,DHRS9,ELOVL4,FA2H,FADS6,FGFR4,GAD1,MALRD1,OSBPL6,PLP1,PTGIS,RBP1,RDH10,RGN,SDS,VCAN |
| GO_REGIONALIZATION | 0.0e+00 | 7.0e-07 | 1813 | 354 | 36 | ACVR2A,AHI1,ALX4,CHRD,CYP26B1,DISP1,DLL4,EGR2,EOMES,EPB41L5,FGFR1,FGFR2,FOXA1,GLI1,GREM1,GREM2,HES2,HEY2,HEYL,ITGAM,LMX1B,LRP6,MEOX1,MESP2,MSX2,NKD1,NKX2-1,NKX3-1,NKX6-1,NRP2,PCSK5,PITX2,ROBO1,SNAI1,SOSTDC1,TDGF1P3 |
| GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 0.0e+00 | 7.0e-07 | 1813 | 537 | 47 | ADCYAP1R1,ADRA1A,AKAP6,AP3B2,ARL6,BICDL1,BICDL2,CACNA2D1,CDH3,CEP19,CEP83,CNIH2,CORO1A,DRD2,F5,FAM155A,FKBP1B,GEM,GPR143,GRIK5,GRIN1,HAP1,HTR2A,KIF13A,KIF5A,KIF5C,LTF,MAPK15,NOS1,P2RX7,PLCD1,PLCH1,PLCL2,PPP6C,PRKCZ,PTPRN2,RAB17,RAD21L1,RYR1,RYR3,SCFD1,SCRIB,SEC22B,SLC2A4,SYBU,TRPA1,VSNL1 |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 7.0e-07 | 1813 | 752 | 59 | AP3B2,APC2,ARHGEF10,BICDL1,BICDL2,BMERB1,CAMSAP3,CAPN6,CDC14A,CEP19,CFAP53,CFAP61,CNIH2,CRIPT,CRMP1,DNAAF3,DNAH12,DNAH2,DNAH7,DNAI1,DYNLL1,EML1,EML4,FSD1,HAP1,HOOK1,HYDIN,IFT20,IFT80,JHY,KIAA1614,KIF13A,KIF13B,KIF21B,KIF27,KIF5A,KIF5C,KLC3,LRGUK,MAP1S,MAP6,MAP6D1,MAP7,MAPK15,MAPRE3,MARK1,NEURL1,PARD6G,PRKCZ,PTK2,STMND1,SYBU,TACC1,TEKT1,TPPP3,TUB,TUBA3C,TUBB2A,TUBB4A |
| GO_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 7.0e-07 | 1813 | 152 | 22 | ARHGAP4,BCL11A,CD38,CDKL3,CRMP1,DCC,DPYSL3,DRAXIN,EPHB2,ITM2C,LINGO1,MYLIP,NFATC4,NGFR,NR2F1,NTN1,PTK2,RAB29,RGMA,RTN4RL2,SEMA4D,SEMA7A |
| GO_NEGATIVE_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 8.0e-07 | 1813 | 294 | 32 | ACER2,ACVRL1,ADAM22,ARHGAP6,BMP6,BTN2A2,CD74,CD86,CDH1,CDKN2A,CEACAM1,DUSP1,EPB41L5,FGG,FGL1,HAVCR2,HLX,JAK2,JAM3,KNG1,MBP,MIA3,PELI1,PLA2G2D,PODXL,POSTN,PTK2,RUNX3,SEMA4D,SH2B3,SPN,ZNF703 |
| GO_INOSITOL_LIPID_MEDIATED_SIGNALING | 0.0e+00 | 8.0e-07 | 1813 | 193 | 25 | BTN2A2,CBL,CEACAM1,CSF1R,FGFR1,GPR143,HTR2A,JAK2,NKX3-1,NYAP2,PI4KAP2,PIK3AP1,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLCD1,PLCH1,PLCL2,PPP1R16B,PREX2,PTAFR,PTK2,SEMA4D,UNC5B |
| GO_EPITHELIAL_CELL_DEVELOPMENT | 0.0e+00 | 8.0e-07 | 1813 | 207 | 26 | BMP6,DMRT1,EPB41L5,FGFR1,FOXA1,GPAT4,GPR4,GSTM3,HNF4A,HOXB13,HYDIN,KLF5,MAGI2,NKX6-1,NUP210L,PODXL,PPP1R16B,RARB,S1PR3,SCRIB,SLC4A5,SPDEF,TFCP2L1,TIGAR,TJP1,VSIG1 |
| GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 0.0e+00 | 8.0e-07 | 1813 | 373 | 37 | ADAMTS14,ADAMTS20,ADAMTS3,ANXA9,CDH1,COL19A1,COL4A3,COL5A3,COMP,CSGALNACT1,EXOC8,FGFR4,FGG,FMOD,GREM1,ICAM2,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,JAM3,KLK7,KLKB1,LAMA4,MMP13,MMP16,NDNF,POSTN,PTK2,SCUBE1,SERAC1,SPINT1,SPOCK2,SULF2,TLL2,VCAN |
| GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 8.0e-07 | 1813 | 310 | 33 | ARHGAP4,BCL11A,BMERB1,BRINP1,CALR,CD38,CDKL3,CEND1,CRMP1,DCC,DISP3,DPYSL3,DRAXIN,EPHB2,GPR37L1,ITM2C,LIN28A,LINGO1,MYLIP,NFATC4,NGFR,NKX6-1,NOTCH3,NR2F1,NTN1,PTK2,RAB29,RGMA,RTN4RL2,SEMA4D,SEMA7A,SLC6A4,SLIT1 |
| GO_SPHINGOLIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 8.0e-07 | 1813 | 105 | 18 | ACER2,ACER3,ALDH3B2,B4GALT5,ELOVL4,FA2H,ORMDL3,P2RX7,PLPP2,PPM1L,PRKD2,SGPP1,ST3GAL5,ST8SIA1,ST8SIA6,TLCD3B,UGCG,UGT8 |
| GO_REGULATION_OF_PROTEIN_DEPOLYMERIZATION | 0.0e+00 | 8.0e-07 | 1813 | 83 | 16 | ACTN2,ADD2,APC2,BMERB1,CAMSAP3,CFL2,CRACD,MAP1S,MAP6D1,NES,PLEKHH2,SCIN,SLN,SPTA1,SPTAN1,SPTB |
| GO_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY | 0.0e+00 | 9.0e-07 | 1813 | 73 | 15 | ABHD5,ADCYAP1R1,ADRA1A,ARHGAP6,AVPR1A,FGFR1,FGFR2,FGFR3,HTR2A,ITK,NMUR1,PLIN5,PRKCZ,PTAFR,TXK |
| GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 1.0e-06 | 1813 | 223 | 27 | ARHGAP4,BCL11A,CALR,CD38,CDKL3,CRMP1,DCC,DISP3,DPYSL3,DRAXIN,EPHB2,GPR37L1,ITM2C,LINGO1,MYLIP,NFATC4,NGFR,NOTCH3,NR2F1,NTN1,PTK2,RAB29,RGMA,RTN4RL2,SEMA4D,SEMA7A,SLC6A4 |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 1.0e-07 | 1.0e-06 | 1813 | 723 | 57 | ACER2,ACER3,ACSM2A,ACSM3,ADA2,ADCYAP1R1,AKR1D1,ALOX15,AVPR1A,BMP6,CD74,CEACAM1,CSPG5,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP39A1,CYP46A1,DHRS9,ELOVL4,ENTPD3,FA2H,FADS6,FGFR4,GAD1,GGTLC3,GLS,GLS2,MALRD1,MDH1,MTAP,NOXRED1,OAT,OSBPL6,P2RY1,PDE10A,PDE4C,PLA2G4A,PLCD1,PLCH1,PLCL2,PLP1,PPIP5K1,PRTFDC1,PTAFR,PTGIS,RBP1,RDH10,RGN,RIMKLA,RIMKLB,SAMHD1,SDS,SNAI1,SRD5A2,VCAN |
| GO_CELLULAR_RESPONSE_TO_LIPID | 1.0e-07 | 1.0e-06 | 1813 | 615 | 51 | AHR,AICDA,ATP1A3,BCL2L11,BMP6,BRINP1,BRINP2,CALR,CASR,CD40,CD6,CD86,CLU,CPT1A,CX3CR1,CYP26B1,ESRRB,FFAR2,FGFR2,FOXA1,HAVCR2,HCK,HEYL,HNF4A,IL12A,JAK2,KCNMB1,LILRA2,LRP6,LTF,MAP4K1,MRC1,MSX2,NFATC4,NKX3-1,NOS2,NR2C1,NR2F1,NR5A2,NR6A1,NUGGC,POU4F1,PTAFR,PTGER4,RARB,RORB,SCIMP,SLC6A4,SSTR2,TESC,ZNF703 |
| GO_ERBB_SIGNALING_PATHWAY | 1.0e-07 | 1.0e-06 | 1813 | 143 | 21 | AFAP1L2,CBL,CEACAM1,GAREM1,GRB2,HAP1,LGMN,MATK,NCK2,NEURL1,NRG2,PIGR,PTK2,PTPN3,REPS2,SH3TC2,SHKBP1,SLC30A10,SOCS4,STAM2,ZGPAT |
| GO_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | 1.0e-07 | 1.0e-06 | 1813 | 64 | 14 | CEACAM1,CORO1A,CRTAM,HAVCR2,IL12A,NECTIN2,RAET1G,SERPINB9,SH2D1A,SLAMF7,ULBP1,ULBP2,ULBP3,VAV1 |
| GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORT | 1.0e-07 | 1.0e-06 | 1813 | 143 | 21 | ASIC1,ASIC3,ATP1A3,ATP1B1,ATP1B2,CACNA1G,CACNA1I,DRD4,FXYD7,HCN2,HCN4,NEDD4L,NOS1,PTPN3,SCN3A,SCN3B,SCN4B,SCN5A,SCNN1D,SLC24A4,TESC |
| GO_SKELETAL_SYSTEM_MORPHOGENESIS | 1.0e-07 | 1.1e-06 | 1813 | 239 | 28 | ALX4,ANXA9,BARX2,BMP6,COMP,CSGALNACT1,CYP26B1,EIF4A3,FGF18,FGFR1,FGFR2,FGFR3,GREM1,HOXA1,IFT80,IRX5,LRP6,LTF,MMP13,MMP16,MSX2,P2RX7,PAX5,PHOSPHO1,RARB,RDH10,SP5,VWA2 |
| GO_REGULATION_OF_LEUKOCYTE_MIGRATION | 1.0e-07 | 1.1e-06 | 1813 | 197 | 25 | AKIRIN1,C5,CALR,CAMK1D,CCN3,CCR6,CD74,CX3CR1,CXCR2,DAPK2,DOCK8,DUSP1,FPR2,GCSAML,GREM1,IL12A,IL33,JAM3,LGMN,MIA3,MPP1,NCKAP1L,PTAFR,PTGER4,SPN |
| GO_RESPONSE_TO_MECHANICAL_STIMULUS | 1.0e-07 | 1.1e-06 | 1813 | 211 | 26 | ANO3,ASIC3,ATP8A2,BMP6,CD40,CHRNA10,DRD2,HTR2A,IGFBP2,JUN,KCNC1,KCNK2,NRXN1,NRXN2,P2RX7,P2RY1,PKD1L2,POSTN,PTGER4,SCEL,STRBP,TLR5,TLR7,TMEM150C,TNFRSF8,TRPA1 |
| GO_AMINO_ACID_TRANSPORT | 1.0e-07 | 1.2e-06 | 1813 | 144 | 21 | AVPR1A,CPLX1,GLS,GLS2,GRM7,LRRC8C,LRRC8E,P2RX7,SLC16A10,SLC17A8,SLC1A4,SLC1A6,SLC36A2,SLC36A3,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLC6A14,STX1A,XK |
| GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 1.0e-07 | 1.2e-06 | 1813 | 157 | 22 | AMIGO1,CALR,CAMK2B,CDKL3,CHODL,CSPG5,FBXO31,FGG,IL1RAPL1,ISLR2,IST1,KALRN,MAP6,NGFR,NTN1,RND2,ROBO1,SEMA4D,SEMA7A,SHTN1,TRPV2,ZFYVE27 |
| GO_T_CELL_DIFFERENTIATION | 1.0e-07 | 1.2e-06 | 1813 | 240 | 28 | BTN2A2,CAMK4,CARD11,CCR6,CD1D,CD3D,CD74,CD83,CD86,CYP26B1,DLL4,EOMES,HLX,IL12A,IL23R,IL7,ITK,LY9,NCKAP1L,PLA2G2D,PRKCZ,PTGER4,RUNX3,SOX4,SPN,TCF7,TESPA1,VAV1 |
| GO_PROTEIN_MATURATION | 1.0e-07 | 1.2e-06 | 1813 | 285 | 31 | ACE,ADAMTS3,ANXA9,BACE2,CALR,COMP,CORIN,CPM,CPZ,CST7,CYFIP2,DISP1,FGG,FKBP1B,IL1R2,KLK1,KLKB1,LGMN,MMP16,MYRF,P2RX7,PCSK2,PCSK5,PLAT,SIRT4,SOX4,TESC,TMPRSS2,TSPAN15,TSPAN33,TSPAN5 |
| GO_CELL_MATRIX_ADHESION | 1.0e-07 | 1.2e-06 | 1813 | 226 | 27 | ACER2,ACTN2,ACVRL1,ARHGAP6,BCL2L11,CAMSAP3,CD34,CDKN2A,COL19A1,COL5A3,EDA,EMP2,EPB41L5,EPDR1,FGG,GREM1,ITGA6,ITGAL,ITGB7,JAM3,LYPD5,OTOA,POSTN,PRKCZ,PTK2,TESK2,VWA2 |
| GO_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | 1.0e-07 | 1.2e-06 | 1813 | 38 | 11 | CACNA1G,CACNA2D1,CACNB2,DSC2,HCN4,KCNE5,KCNH2,KCNJ5,SCN3B,SCN4B,SCN5A |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1.0e-07 | 1.2e-06 | 1813 | 620 | 51 | ACER2,BTN2A2,C1QL4,CADM4,CBL,CDKN2A,CDYL,CEACAM1,CEBPA,CHRNA10,DRD2,DUSP1,DUSP26,DUSP9,ELFN1,EPHB2,FKBP1B,GFRA2,GREM1,GSKIP,JUN,KDM1A,KIRREL2,KLHL31,LDLRAD4,LMTK2,LRP6,MAPK8IP1,NCK2,NCKAP1L,NDRG2,NXN,P2RX7,PAX5,PPP1R14C,PPP1R16B,PPP1R1C,PRKAR2B,PRKCG,PRKCZ,RGN,SEMA4D,SH2B3,SH3RF2,SOCS4,SOX4,SRCIN1,TESC,TIMP3,VRK3,ZGPAT |
| GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | 1.0e-07 | 1.4e-06 | 1813 | 56 | 13 | CACNA1G,CACNA2D1,CACNB2,DSC2,KCNE5,KCNH2,KCNJ5,KCNN2,NEDD4L,NOS1AP,SCN3B,SCN4B,SCN5A |
| GO_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 1.0e-07 | 1.5e-06 | 1813 | 186 | 24 | ACTN2,AKAP6,AMIGO1,CACNA2D1,CACNB2,CACNG7,CNIH2,DAPK1,DRD2,DRD4,EPHB2,FGF14,FKBP1B,GEM,GRIN1,HAP1,KCNC1,KCNE5,KCNJ11,MAPK8IP2,NOS1,NOS1AP,RASGRF1,RGS9 |
| GO_NEGATIVE_REGULATION_OF_SECRETION | 1.0e-07 | 1.5e-06 | 1813 | 243 | 28 | ACVR1C,ASIC1,BMP8A,BTN2A2,CCN3,CD22,CD34,CD74,CEACAM1,DRD2,DRD4,ENHO,FKBP1B,GRM7,IL11,IL1R2,IL1RAPL1,IL33,INHBB,KALRN,KCNJ11,P2RY1,PSMD9,PTGER4,SIRT4,SRCIN1,TRIM9,VSNL1 |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 1.0e-07 | 1.5e-06 | 1813 | 518 | 45 | ALS2,C5,CD40,CD74,CDK5R2,CDKN2A,CEBPA,CHRNA7,CNTD2,CSF1R,DIRAS3,DRD4,DUSP1,DUSP9,EPHB2,FGD2,FGF18,FGFR1,GHR,HERC5,HIGD1A,HTR2A,JAK2,KSR1,LRP6,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MAPRE3,MUC20,NOX4,NPFFR2,P2RX7,PIK3R5,PRKAR2B,ROBO1,SH2B3,STK3,SYAP1,TENM1 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 1.0e-07 | 1.5e-06 | 1813 | 1280 | 85 | AHR,AICDA,BAHD1,BARX2,BCL11A,BMP6,BTRC,CALR,CD38,CDKN2A,CDYL,CEBPA,CIITA,CPEB3,CRYM,DLL4,DLX4,DMAP1,DMRT1,DUSP26,EIF4A2,EOMES,ETV3,ETV7,FGFR1,FGFR2,FOXA1,GLIS3,GREM1,HES2,HESX1,HEY2,HEYL,HIC2,HNF4A,HOXB13,IKZF5,JUN,KDM1A,KLF5,MAPK10,MSX2,NCK2,NEDD4L,NFATC4,NFE2L3,NKX2-1,NKX3-1,NKX6-1,NOSTRIN,NOTCH3,NPAS1,NR2C1,NR2F1,NR6A1,PAX5,PAX9,POU4F1,PRAME,PRDM6,RARB,RGN,RITA1,RORB,RUNX3,SALL2,SEMA4D,SFMBT2,SLA2,SNAI1,SNAI3,SOX6,SP5,SPDEF,TCF7,TFCP2L1,TLE3,UBA3,UBE2D1,ZGPAT,ZNF253,ZNF431,ZNF703,ZNF93,ZNFX1 |
| GO_NEURON_MIGRATION | 1.0e-07 | 1.6e-06 | 1813 | 160 | 22 | ASTN1,ATOH1,CAMK2B,CDK5R2,DCC,DCDC2,DCLK1,DRD2,FBXO31,FGFR1,LHX6,MARK1,MDGA1,NDNF,NKX2-1,NKX6-1,NRP2,NTN1,POMGNT2,PTK2,SHTN1,TUBB2A |
| GO_SPHINGOLIPID_METABOLIC_PROCESS | 1.0e-07 | 1.6e-06 | 1813 | 160 | 22 | ACER2,ACER3,ALDH3B2,B4GALT5,ELOVL4,ESYT3,FA2H,ORMDL3,P2RX7,PLPP2,PPM1L,PRKD2,SFTPB,SGPP1,SMPDL3B,SPNS2,ST3GAL5,ST8SIA1,ST8SIA6,TLCD3B,UGCG,UGT8 |
| GO_T_CELL_PROLIFERATION | 1.0e-07 | 1.6e-06 | 1813 | 187 | 24 | BTN2A2,CARD11,CD1D,CD209,CD6,CD70,CD86,CORO1A,DOCK8,FKBP1B,HAVCR2,HHLA2,HLA-DPB1,IGFBP2,IL12A,IL23R,MAPK8IP1,NCK2,NCKAP1L,P2RX7,PELI1,PLA2G2D,SPN,SPTA1 |
| GO_NEURON_DEATH | 1.0e-07 | 1.7e-06 | 1813 | 353 | 35 | AGAP2,BCL2L11,CBL,CD34,CHRNA7,CLU,CORO1A,CRLF1,CX3CR1,DCC,DRAXIN,FGF21,FZD9,GABRB2,GRIK5,GRIN1,ITGAM,JAK2,JUN,LGMN,MT1F,NDNF,NES,NFATC4,NGFR,POU4F1,POU4F3,PRKCG,PTPRZ1,RAB29,SLC25A27,SLC30A10,SRPK2,TIGAR,UNC5B |
| GO_CELL_CELL_JUNCTION_ORGANIZATION | 1.0e-07 | 1.8e-06 | 1813 | 188 | 24 | ACE,BMP6,CADM2,CAMSAP3,CDH1,CDH15,CDH2,CDH3,CDHR3,CSF1R,ESAM,GPBAR1,GRHL1,JAM3,LSR,NECTIN2,NFASC,OCLN,PARD6G,SDK2,SNAI1,TJP1,UGT8,ZNF703 |
| GO_CELL_CHEMOTAXIS | 1.0e-07 | 1.8e-06 | 1813 | 306 | 32 | ABCC1,AKIRIN1,C5,CALR,CAMK1D,CCL26,CCN3,CCR6,CCRL2,CD74,CORO1A,CX3CR1,CXCR2,DAPK2,DUSP1,ELMO2,FFAR2,FGF18,FGFR1,FPR2,GREM1,IL12A,IL16,JAM3,LGMN,MPP1,NCKAP1L,PRKD2,S100A9,SAA4,SCG2,VAV1 |
| GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 1.0e-07 | 1.8e-06 | 1813 | 436 | 40 | ALS2,ANO3,ANO9,CAMSAP3,CLU,CNEP1R1,CRB1,EXOC8,FA2H,GOLGA8IP,GOLGA8S,HOOK1,IST1,MAPK15,MIA3,MYRF,NECTIN2,P2RX7,PARP11,RAB29,REEP1,RTN3,SH3TC2,SHTN1,SPTA1,STAM2,STX6,SYP,SYPL2,TBPL1,TMED6,TMEFF2,TOR1AIP2,TOR1B,UGCG,USP6NL,VMP1,XKR4,XKR5,ZFYVE27 |
| GO_INORGANIC_ION_IMPORT_ACROSS_PLASMA_MEMBRANE | 1.0e-07 | 1.8e-06 | 1813 | 88 | 16 | ATP1A3,ATP1B1,ATP1B2,CACNA2D1,FAM155A,HCN2,HCN4,KCNH2,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNK9,SLC12A8 |
| GO_GLIAL_CELL_DIFFERENTIATION | 1.0e-07 | 1.9e-06 | 1813 | 217 | 26 | ADAM22,ARHGEF10,B4GALT5,BACE2,CDH2,CLU,CSPG5,EGR2,FA2H,FPR2,GCM1,GPR37L1,IL34,LIN28A,METTL14,MYRF,NKX2-1,NKX6-1,PLP1,PTPRZ1,SH3TC2,SOX4,SOX6,SPINT1,TSPAN2,WASF3 |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 1.0e-07 | 1.9e-06 | 1813 | 594 | 49 | ABHD5,ACHE,ACSL6,ADCY4,ADCYAP1R1,AGAP2,AK5,AK7,AK9,ALOX15,BMX,DDHD1,ELOVL4,ETNPPL,FPR2,GPAT4,GUCA1B,GUCA1C,GUCY1A1,GUCY1A2,GUCY1B1,HTR2A,LIPH,LIPI,LPCAT2,MOCS2,NOS1,NOS2,P2RY1,PANK3,PCYT1B,PHOSPHO1,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLCD1,PLCH1,PLCL2,PPIP5K1,PTAFR,PTGIS,PYGL,SBF1,SERAC1,SLC44A3,TBPL1 |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 1.0e-07 | 1.9e-06 | 1813 | 189 | 24 | AKAP6,ATP8A2,CACNA2D2,CACNG7,DRD2,FGFR1,FGFR2,GHR,GLI1,HEY2,HLX,IL7,ISLR2,IST1,NEDD4L,NTN1,PLS1,RND2,SEMA4D,SEMA7A,SHTN1,SYT2,TRPV2,ZFYVE27 |
| GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | 1.0e-07 | 2.0e-06 | 1813 | 292 | 31 | ACHE,BMP6,C5,CASR,CD34,CD38,CRTAM,CSF1R,DOC2B,DRD2,FCN1,FFAR2,FGG,HAVCR2,IL33,ILDR1,JAK2,LILRA2,MAPK11,MBP,NKX6-1,P2RX7,PAEP,POSTN,PRKCZ,PSMD9,PTGER4,SCAMP5,SOX4,SYBU,VSNL1 |
| GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 1.0e-07 | 1.9e-06 | 1813 | 387 | 37 | ACTN2,ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP44,ARHGAP6,ARHGEF10,CCL26,CFL2,CORO1A,CRACD,CSF1R,DSC2,ESAM,FCHSD1,GPR65,GRB2,HCK,HCN4,JAM3,NCK2,NCKAP1L,NOS1AP,NOX4,PLEKHH2,PTGER4,RHOV,RND2,SCIN,SCN5A,SPTA1,SPTAN1,SPTB,TENM1,TMEFF2,WAS |
| GO_REGULATION_OF_BODY_FLUID_LEVELS | 1.0e-07 | 1.9e-06 | 1813 | 506 | 44 | ADCY4,ANXA9,CD34,CD40,CEACAM1,COMP,CYP26B1,CYP4F12,DOCK8,DRD2,EMP2,EPHB2,F5,FA2H,FGG,GPAT4,GRHL1,GUCA1B,HBE1,HBG2,HNF4A,HSD11B2,JAK2,JHY,KALRN,KDM1A,KLKB1,KNG1,LSR,NEURL1,OPRK1,P2RX7,P2RY1,PIK3R5,PLAT,PRKAR2B,PRKCG,SCUBE1,SH2B3,SLC29A1,SLC4A5,UGCG,VAV1,WAS |
| GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | 1.0e-07 | 1.9e-06 | 1813 | 261 | 29 | ADCYAP1R1,AKAP6,ANXA9,ATP1B1,CACNA2D1,CACNB2,CAMK2B,CASR,CORO1A,DRD2,DRD4,FGF14,FKBP1B,GEM,GNAO1,GRIN1,HAP1,IL16,LILRA2,MRLN,NOS1,NOS1AP,OPRD1,P2RX7,RGN,RGS9,SLN,TRPV2,TRPV3 |
| GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION | 1.0e-07 | 2.0e-06 | 1813 | 32 | 10 | CACNA1G,CACNA2D1,CACNB2,HCN4,KCNE5,KCNJ5,KCNN2,SCN3B,SCN4B,SCN5A |
| GO_INTERACTION_WITH_HOST | 1.0e-07 | 2.1e-06 | 1813 | 204 | 25 | BCL2L11,CBL,CD209,CD74,CD86,CDH1,CDHR3,CR2,FCN1,GRB2,GUCY1A1,HTR2A,IST1,ITGB7,KPNA1,KPNA5,KPNA7,MRC1,NCAM1,NECTIN2,SCRIB,SELPLG,SERPINB9,TMPRSS2,XPR1 |
| GO_MEMBRANE_REPOLARIZATION | 1.0e-07 | 2.3e-06 | 1813 | 49 | 12 | AKAP6,ATP1B1,ATP1B2,CACNA2D1,KCNE5,KCNH2,KCNJ5,KCNN2,NEDD4L,NOS1AP,SCN4B,SCN5A |
| GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 1.0e-07 | 2.3e-06 | 1813 | 544 | 46 | ACVRL1,AHI1,ANKRD6,BTRC,CAMSAP3,CASR,CEACAM1,CSF1R,CXCR2,DLL4,EOMES,EPB41L5,FGFR1,FGFR2,FOXA1,FRAS1,FREM2,GCM1,GRB2,GREB1L,GREM1,HESX1,HOXB13,IFT20,ITGAX,KIF26B,LGR5,LRP6,MAGI2,MSX2,NFATC4,NKD1,NKX2-1,NKX3-1,NTN1,PODXL,PRKD2,PSMD9,RDH10,SCRIB,SNAI1,SOSTDC1,SOX4,SPINT1,STK3,TMEFF2 |
| GO_BONE_MORPHOGENESIS | 1.0e-07 | 2.4e-06 | 1813 | 113 | 18 | ANXA9,BMP6,COMP,CSGALNACT1,CYP26B1,FGF18,FGFR2,FGFR3,IFT80,LRP6,LTF,MMP13,MMP16,MSX2,PHOSPHO1,RARB,SP5,VWA2 |
| GO_POSITIVE_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | 2.0e-07 | 2.6e-06 | 1813 | 59 | 13 | ADCYAP1R1,ADRA1A,ARHGAP6,AVPR1A,FGFR1,FGFR2,FGFR3,HTR2A,ITK,NMUR1,PRKCZ,PTAFR,TXK |
| GO_LIPID_CATABOLIC_PROCESS | 2.0e-07 | 2.7e-06 | 1813 | 328 | 33 | ABHD5,ABHD6,ACER2,ACER3,AKR1D1,CES3,CPT1A,CPT1C,CYP1A2,CYP26B1,CYP27A1,CYP39A1,CYP46A1,CYP4F12,CYP4F3,DDHD1,ENPP6,ETFBKMT,FABP6,FGF21,GDPD1,HSD17B6,LIPH,LIPI,PLA2G2D,PLA2G4A,PLA2G4E,PLAAT1,PLCD1,PLCH1,PLCXD3,PLIN5,SMPDL3B |
| GO_MEMBRANE_LIPID_METABOLIC_PROCESS | 2.0e-07 | 2.8e-06 | 1813 | 207 | 25 | ACER2,ACER3,AGMO,ALDH3B2,B4GALT4,B4GALT5,ELOVL4,ESYT3,FA2H,ORMDL3,P2RX7,PLPP2,PPM1L,PRKD2,SFTPB,SGPP1,SMPDL3B,SPNS2,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,TLCD3B,UGCG,UGT8 |
| GO_NOTCH_SIGNALING_PATHWAY | 2.0e-07 | 2.8e-06 | 1813 | 193 | 24 | ATOH1,BMP2K,CCN3,CEBPA,CNTN1,DLL4,DTX4,ENHO,FOXA1,HEY2,HEYL,MESP2,NEURL1,NEURL1B,NOTCH3,POSTN,RITA1,ROBO1,S1PR3,SNAI1,TIMP4,TMEM100,TSPAN15,TSPAN5 |
| GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | 2.0e-07 | 3.1e-06 | 1813 | 115 | 18 | ATOH1,BMP6,CDH2,FGFR1,FGFR2,FOXA1,GPAT4,HEY2,HNF4A,KLF5,MYCL,NKX6-1,POU4F3,RARB,SCRIB,SOX4,SPDEF,TIGAR |
| GO_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT | 2.0e-07 | 3.1e-06 | 1813 | 115 | 18 | ANO3,ANO9,CASR,CLCA3P,CLCN4,CLIC5,GABRA1,GABRA6,GABRB2,GABRD,GABRP,GABRQ,GLRA3,PTAFR,SLC12A8,SLC1A4,TTYH2,XPR1 |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 2.0e-07 | 3.1e-06 | 1813 | 604 | 49 | AKIRIN1,CALR,CAMK1D,CASR,CCL26,CCR6,CD40,CD74,CLEC7A,CORO1A,CSF1R,CX3CR1,CXCR2,DAPK2,DOCK8,EPB41L5,FBXO31,FGF18,FGFR1,FLT4,FPR2,IL12A,IL16,ITGA6,ITGAX,JAK2,JUN,LGMN,LRRC15,MAP2K3,MIA3,NCKAP1L,NOX4,NRP2,NTN1,PODXL,POSTN,PRKD2,PTAFR,PTK2,SCG2,SEMA4D,SEMA7A,SH3RF2,SHTN1,SNAI1,SPN,SPOCK2,ZNF703 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 2.0e-07 | 3.2e-06 | 1813 | 1470 | 93 | ACVRL1,AHR,AICDA,BAHD1,BARX2,BCL11A,BMP6,BTRC,CALR,CD38,CDK9,CDKN2A,CDYL,CEBPA,CELF4,CIITA,CPEB3,CRYM,DLL4,DLX4,DMAP1,DMRT1,DUSP1,DUSP26,EIF4A2,EOMES,ETV3,ETV7,FGFR1,FGFR2,FOXA1,GLIS3,GREM1,HES2,HESX1,HEY2,HEYL,HIC2,HNF4A,HOXB13,IKZF5,JUN,KCNK2,KDM1A,KLF5,MAPK10,MSX2,NCK2,NEDD4L,NFATC4,NFE2L3,NKX2-1,NKX3-1,NKX6-1,NOSTRIN,NOTCH3,NPAS1,NR2C1,NR2F1,NR6A1,PAX5,PAX9,POU4F1,PRAME,PRDM6,RARB,RBM24,RBM38,RGN,RITA1,RORB,RUNX3,SALL2,SEMA4D,SFMBT2,SLA2,SNAI1,SNAI3,SOX6,SP5,SPDEF,TCF7,TFCP2L1,TIGAR,TLE3,UBA3,UBE2D1,ZGPAT,ZNF253,ZNF431,ZNF703,ZNF93,ZNFX1 |
| GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION | 2.0e-07 | 3.4e-06 | 1813 | 154 | 21 | ACVR1C,BMP8A,BTN2A2,CCN3,CD22,CD34,CD74,DRD2,DRD4,ENHO,FKBP1B,IL1R2,IL33,INHBB,KALRN,KCNJ11,PSMD9,PTGER4,SIRT4,SRCIN1,VSNL1 |
| GO_REGULATION_OF_DEPHOSPHORYLATION | 2.0e-07 | 3.3e-06 | 1813 | 209 | 25 | CAMSAP3,CHP2,CNEP1R1,DRD2,DUSP26,ELFN1,FKBP1B,GPATCH2,JAK2,LMTK2,LMTK3,MAGI2,NCKAP1L,PPP1R14C,PPP1R16B,PPP1R1C,PPP1R42,PPP2R2C,RGN,RIMBP2,SEMA4D,SFI1,SH3RF2,SYMPK,VRK3 |
| GO_VESICLE_LOCALIZATION | 2.0e-07 | 3.6e-06 | 1813 | 210 | 25 | AP3B2,ARL6,BICDL1,BICDL2,CDH2,CDH3,CEP19,CNIH2,F5,GPR143,HAP1,KIF13A,KIF5A,KIF5C,MAGI2,MAPK15,PPP6C,PRKCZ,RAB17,SCFD1,SCRIB,SEC22B,SLC2A4,SYBU,SYN3 |
| GO_LOCALIZATION_WITHIN_MEMBRANE | 2.0e-07 | 3.8e-06 | 1813 | 93 | 16 | ARL6,ATP1B1,CDH2,CNIH2,FZD9,GRIK5,ITGAL,ITGB7,MAGI2,MESD,MIA3,NRXN1,NRXN2,PIGR,SCRIB,TMEFF2 |
| GO_NEGATIVE_REGULATION_OF_HORMONE_SECRETION | 2.0e-07 | 3.8e-06 | 1813 | 61 | 13 | ACVR1C,BMP8A,CCN3,DRD2,ENHO,FKBP1B,IL11,INHBB,KALRN,KCNJ11,PSMD9,SIRT4,VSNL1 |
| GO_REGULATION_OF_BLOOD_PRESSURE | 2.0e-07 | 4.0e-06 | 1813 | 183 | 23 | ACE,ACSM3,ACVRL1,ADRA1A,AVPR1A,CD34,CORIN,CYP4F12,DRD2,EMP2,GPR37L1,GUCY1A1,HSD11B2,KLK1,NCALD,NOS1,NOS2,NPY1R,PCSK5,POSTN,PTAFR,SLC4A5,TNNI3 |
| GO_EMBRYONIC_ORGAN_DEVELOPMENT | 2.0e-07 | 4.1e-06 | 1813 | 434 | 39 | AHI1,ALX4,ATOH1,ATP8A2,CEBPA,CHRNA10,EIF4A3,EOMES,EPHB2,FGFR1,FGFR2,GCM1,GLI1,GRB2,HESX1,HEY2,HLX,HOXA1,HS6ST1,IRX5,KCNQ4,LRP6,MMP16,NES,NTN1,PAX5,PCDH12,PCSK5,PLCD1,POU4F3,RARB,RDH10,SCRIB,SH2B3,SNAI1,SPINT1,STK3,TCF7,VASH2 |
| GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | 3.0e-07 | 4.2e-06 | 1813 | 212 | 25 | ADCY4,ADCYAP1R1,ADGRB2,ADGRB3,ADGRE1,ADGRL1,ADGRL2,ADRA1A,AHR,AKAP6,DRD2,GNAL,GPR65,GUCY1B1,IAPP,KSR1,LGR5,MC2R,NOS1,PDE10A,PDE11A,PEX5L,PRKAR2B,PTGER4,RUNDC3A |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 3.0e-07 | 4.2e-06 | 1813 | 1151 | 77 | AGPS,AKAP6,AP1B1,AP1S3,AP3B2,ARHGAP44,ARL14,ARL6,ATP1B1,CABP1,CALR,CAMSAP3,CD74,CDH1,CHP2,CLU,DDX25,DMAP1,DYNLL1,EGR2,EIF4A3,EVI5,GGA2,GOLGA7,GRTP1,HAP1,HUWE1,IFT20,IFT80,ITGAM,KIF13A,KIF13B,KIF5A,KIF5C,KPNA1,KPNA5,KPNA7,NAPG,NGFR,NOS2,OAZ2,PEX5L,RAB17,RAB29,RAB33A,RAB37,RAB3B,RAB44,RAB9B,RGPD3,RPH3A,SCRIB,SGSM1,SGSM3,SGTB,SH3TC2,SIRT4,SNX2,STAM2,STX11,STX12,STX1A,STX6,SYMPK,SYTL5,TBC1D1,TBC1D29P,TBC1D30,TENM1,TMED6,TMEM30A,TUB,UBE2D1,USP6NL,ZDHHC11B,ZDHHC15,ZDHHC23 |
| GO_REGULATION_OF_CELL_KILLING | 3.0e-07 | 4.3e-06 | 1813 | 94 | 16 | AZGP1,BCL2L11,CD1D,CEACAM1,CLEC7A,CRTAM,HAVCR2,IL12A,IL23R,ITGAM,NECTIN2,NOS2,P2RX7,SERPINB9,SH2D1A,VAV1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 3.0e-07 | 4.9e-06 | 1813 | 337 | 33 | ALS2,C5,CD40,CD74,CDK5R2,CHRNA7,CSF1R,DRD4,DUSP9,FGD2,FGF18,FGFR1,GHR,HIGD1A,HTR2A,JAK2,KSR1,LTF,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPRE3,MUC20,NOX4,P2RX7,PIK3R5,ROBO1,STK3,SYAP1,TENM1 |
| GO_LYMPHOCYTE_DIFFERENTIATION | 3.0e-07 | 5.1e-06 | 1813 | 354 | 34 | AICDA,BTN2A2,CAMK4,CARD11,CCR6,CD1D,CD3D,CD74,CD83,CD86,CR2,CYP26B1,DLL4,EOMES,FZD9,HLX,IL11,IL12A,IL23R,IL7,ITK,LY9,NCKAP1L,PLA2G2D,PLCL2,POLM,PRKCZ,PTGER4,RUNX3,SOX4,SPN,TCF7,TESPA1,VAV1 |
| GO_CELL_JUNCTION_ASSEMBLY | 3.0e-07 | 5.2e-06 | 1813 | 244 | 27 | ACE,ACTN2,ACVRL1,ARHGAP6,CAMSAP3,CDH1,CDH15,CDH2,CDH3,CDHR3,EPB41L5,ESAM,GPBAR1,GREM1,ITGA6,JAM3,LSR,NFASC,OCLN,PARD6G,PTK2,SNAI1,TESK2,TJP1,UGT8,VMP1,ZNF703 |
| GO_DRUG_TRANSPORT | 3.0e-07 | 5.2e-06 | 1813 | 200 | 24 | ABCC1,CALHM1,CHRNB2,DRD2,DRD4,GDF9,HBA1,HBE1,HBG2,HTR2A,MAPK15,RAB3B,RTBDN,SLC13A3,SLC17A8,SLC18A2,SLC1A6,SLC36A2,SLC36A3,SLC52A3,SYT13,SYT2,SYT5,TMEM30A |
| GO_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | 3.0e-07 | 5.1e-06 | 1813 | 259 | 28 | ACTN2,ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP6,ARHGEF10,CCL26,CFL2,CORO1A,CRACD,ESAM,FCHSD1,GPR65,GRB2,HCK,NCK2,NCKAP1L,NOX4,PLEKHH2,PTGER4,SCIN,SPTA1,SPTAN1,SPTB,TENM1,TMEFF2,WAS |
| GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | 3.0e-07 | 5.2e-06 | 1813 | 73 | 14 | AZGP1,CD1D,CEACAM1,CRTAM,HAVCR2,IL12A,IL23R,ITGAM,NECTIN2,NOS2,P2RX7,SERPINB9,SH2D1A,VAV1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 3.0e-07 | 5.3e-06 | 1813 | 526 | 44 | ACTR3C,ADGRB2,ADGRB3,ADGRL1,AKIRIN1,ALOX15,AMIGO1,ARHGEF10,BCL2L11,BIK,CBLN2,CCL26,CLEC7A,CLSTN3,CLU,CORO1A,CRACD,DPYSL3,EPB41L5,EPHB2,EPHB3,FCHSD1,GBP5,GPR65,GRB2,HAP1,HCK,IL1RAPL1,KCTD17,MAPK15,NCK2,NCKAP1L,NEURL1,NOX4,NRXN1,P2RX7,PIP4K2A,SCIN,SEMA4D,SLITRK2,SLITRK3,TENM1,TPPP3,WAS |
| GO_POSITIVE_REGULATION_OF_GROWTH | 3.0e-07 | 5.3e-06 | 1813 | 275 | 29 | AKAP6,ATP8A2,AVPR1A,CACNA2D2,CACNG7,CD38,DRD2,FGFR1,FGFR2,GHR,GLI1,HEY2,HLX,IL7,ISLR2,IST1,NEDD4L,NTN1,PLS1,RND2,RPS6KA3,S100A9,SEMA4D,SEMA7A,SHTN1,SYT2,TFCP2L1,TRPV2,ZFYVE27 |
| GO_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 3.0e-07 | 5.4e-06 | 1813 | 491 | 42 | AHR,BTN2A2,CAMK4,CARD11,CD1D,CD209,CD22,CD38,CD40,CD6,CD70,CD74,CD83,CD86,CEACAM1,CHRNB2,CLEC7A,CORO1A,CYP26B1,DOCK8,FGL1,GRB2,HAVCR2,HHLA2,HLA-DPB1,HLX,IGFBP2,IL12A,IL23R,IL7,MAPK8IP1,NCK2,NCKAP1L,PELI1,PLA2G2D,PRKCZ,RUNX3,SLA2,SPN,SPTA1,TESPA1,VAV1 |
| GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 3.0e-07 | 5.5e-06 | 1813 | 291 | 30 | ACTN2,ADGRB3,ADRA1A,AKAP6,AVPR1A,BARX2,BCL9,CACNA2D2,CALR,CCN3,CDH2,CFL2,COMP,CYP26B1,DYRK1B,GREM1,HEY2,IFT20,KLF5,MYL2,MYO18B,NOS1,NOX4,RARB,RBM24,RBM38,RYR1,SOX6,TNNT2,XK |
| GO_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION | 4.0e-07 | 5.7e-06 | 1813 | 96 | 16 | CARD11,CD1D,CD209,CD6,CD70,CD86,CORO1A,HAVCR2,HHLA2,HLA-DPB1,IGFBP2,IL12A,IL23R,NCK2,NCKAP1L,SPTA1 |
| GO_REGULATION_OF_SYNAPTIC_PLASTICITY | 4.0e-07 | 5.8e-06 | 1813 | 187 | 23 | ABHD6,CALB2,CAMK2B,CD38,CHRNA7,CPEB3,CX3CR1,CYP46A1,DRD2,EGR2,EPHB2,FGF14,GRIN1,IGSF11,LGMN,LZTS1,NEURL1,NFATC4,PRKCZ,RASGRF1,RIMS3,SLC4A10,SYP |
| GO_CARDIAC_MUSCLE_CELL_CONTRACTION | 4.0e-07 | 6.1e-06 | 1813 | 74 | 14 | CACNA1G,CACNA2D1,CACNB2,DSC2,HCN4,KCNE5,KCNH2,KCNJ5,KCNN2,NEDD4L,NOS1AP,SCN3B,SCN4B,SCN5A |
| GO_REGULATION_OF_SODIUM_ION_TRANSPORT | 4.0e-07 | 6.1e-06 | 1813 | 85 | 15 | ATP1B1,ATP1B2,CNTN1,DRD2,DRD4,FXYD7,NEDD4L,NKAIN1,NOS1,P2RX7,PTPN3,SCN3B,SCN4B,SCN5A,TESC |
| GO_GLUTAMINE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS | 4.0e-07 | 6.2e-06 | 1813 | 28 | 9 | ADHFE1,ASRGL1,GAD1,GLS,GLS2,NOS1,NOS2,OAT,PADI4 |
| GO_NEUROTRANSMITTER_REUPTAKE | 4.0e-07 | 6.2e-06 | 1813 | 28 | 9 | DRD2,DRD4,NOS1,RAB3B,SLC18A2,SLC29A1,SLC6A1,SLC6A11,SLC6A4 |
| GO_AMINE_TRANSPORT | 4.0e-07 | 6.5e-06 | 1813 | 97 | 16 | AVPR1A,CHRNB2,DDC,DRD2,DRD4,GRM7,HTR2A,P2RX7,P2RY1,RAB3B,SLC18A2,SLC6A1,STX1A,SYT13,SYT2,SYT5 |
| GO_POSITIVE_REGULATION_OF_CELL_KILLING | 4.0e-07 | 6.6e-06 | 1813 | 64 | 13 | AZGP1,BCL2L11,CD1D,CLEC7A,CRTAM,IL12A,IL23R,ITGAM,NECTIN2,NOS2,P2RX7,SH2D1A,VAV1 |
| GO_REGULATION_OF_PHOSPHATASE_ACTIVITY | 4.0e-07 | 6.9e-06 | 1813 | 175 | 22 | CAMSAP3,CHP2,DRD2,ELFN1,FKBP1B,GPATCH2,JAK2,LMTK2,LMTK3,MAGI2,NCKAP1L,PPP1R14C,PPP1R16B,PPP1R1C,PPP1R42,PPP2R2C,RGN,RIMBP2,SEMA4D,SFI1,SH3RF2,VRK3 |
| GO_AXON_EXTENSION | 4.0e-07 | 7.1e-06 | 1813 | 122 | 18 | ARHGAP4,CDKL3,DCLK1,DRAXIN,ISLR2,NKX6-1,NRP2,NTN1,OLFM1,POU4F3,SEMA4D,SEMA5B,SEMA7A,SHTN1,SLIT1,SLIT3,TRPV2,ZFYVE27 |
| GO_PROTEIN_DEPOLYMERIZATION | 5.0e-07 | 7.5e-06 | 1813 | 110 | 17 | ACTN2,ADD2,APC2,BMERB1,CAMSAP3,CFL2,CRACD,MAP1S,MAP6D1,NES,PLEKHH2,SCIN,SLN,SPTA1,SPTAN1,SPTB,STMND1 |
| GO_REGULATION_OF_LIPASE_ACTIVITY | 5.0e-07 | 7.5e-06 | 1813 | 98 | 16 | ABHD5,ADCYAP1R1,ADRA1A,ARHGAP6,AVPR1A,FGFR1,FGFR2,FGFR3,HTR2A,ITK,NMUR1,PCSK5,PLIN5,PRKCZ,PTAFR,TXK |
| GO_CHONDROCYTE_DIFFERENTIATION | 5.0e-07 | 7.9e-06 | 1813 | 123 | 18 | ACVRL1,ANXA9,BMP6,CCN3,COMP,FGF18,FGFR1,FGFR3,GDF6,GREM1,IFT80,MSX2,RARB,RUNX3,SCIN,SOX6,SULF2,VWA2 |
| GO_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | 5.0e-07 | 7.9e-06 | 1813 | 149 | 20 | AGAP2,CORO1A,CRLF1,CX3CR1,DRAXIN,FZD9,GABRB2,GRIN1,JAK2,JUN,LGMN,MT1F,NDNF,NES,NFATC4,POU4F1,PRKCG,PTPRZ1,SLC30A10,UNC5B |
| GO_MONOAMINE_TRANSPORT | 5.0e-07 | 8.1e-06 | 1813 | 87 | 15 | CHRNB2,DRD2,DRD4,HTR2A,MAPK15,NOS1,P2RY1,RAB3B,SLC18A2,SLC29A4,SLC6A4,STX1A,SYT13,SYT2,SYT5 |
| GO_ACTIN_FILAMENT_POLYMERIZATION | 5.0e-07 | 8.3e-06 | 1813 | 177 | 22 | ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP6,CCL26,CORO1A,CRACD,ESAM,FCHSD1,GRB2,HCK,JAK2,NCK2,NCKAP1L,SCIN,SPTA1,SPTAN1,SPTB,TENM1,WAS,WASF3 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 5.0e-07 | 8.4e-06 | 1813 | 111 | 17 | ARHGAP4,BCL11A,CDKL3,DCC,DRAXIN,FGFR3,KCNK2,LGMN,MAPK11,NKD1,NTN1,PTK2,SEMA4D,SEMA7A,SLC6A4,STK3,TLL2 |
| GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS | 6.0e-07 | 8.7e-06 | 1813 | 251 | 27 | ABHD5,ACHE,AGAP2,AGMO,ALOX15,BMX,CNEP1R1,DDHD1,ETNPPL,FPR2,GPAT4,HTR2A,LIPH,LIPI,LPCAT2,PCYT1B,PHOSPHO1,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,PLIN5,RGN,SBF1,SLC44A3 |
| GO_VESICLE_ORGANIZATION | 6.0e-07 | 8.6e-06 | 1813 | 330 | 32 | ALS2,ANXA9,CALR,CD34,CNIH2,CORO1A,CPLX1,DOC2B,EXOC8,F5,GPR143,GRIK5,HOOK1,IST1,KIF13A,MAPK15,MIA3,NECTIN2,P2RX7,PPP6C,SCFD1,SEC22B,SLC2A4,STAM2,STX11,STX12,STX1A,STX6,SYP,TBPL1,TRIM9,ZDHHC15 |
| GO_CELLULAR_PROCESS_INVOLVED_IN_REPRODUCTION_IN_MULTICELLULAR_ORGANISM | 6.0e-07 | 8.9e-06 | 1813 | 347 | 33 | CCR6,CDYL,CELF4,CYP26B1,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,GDF9,HOOK1,INHBB,IZUMO1,JAM3,LGR5,LIN28A,NECTIN2,NEURL1,NOX5,NUP210L,PAEP,PTCHD3,SLIT3,STRBP,TAF1L,TBPL1,TDRKH,TEX11,TSSK1B |
| GO_REGULATION_OF_NERVOUS_SYSTEM_PROCESS | 6.0e-07 | 8.9e-06 | 1813 | 137 | 19 | AVPR1A,CCN3,CELF4,CHRNA7,CHRNB4,CNIH2,CST7,EIF4A3,GRIN1,IGSF11,ITGAX,MYRF,NRXN1,OPRD1,PRKCZ,PTAFR,STX1A,TMEM100,WASF3 |
| GO_XENOBIOTIC_METABOLIC_PROCESS | 6.0e-07 | 8.9e-06 | 1813 | 124 | 18 | AHR,AKR7A3,AKR7L,AOC1,CES3,CYP1A1,CYP1A2,CYP26B1,CYP2B6,CYP2J2,CYP2S1,CYP46A1,GHR,GRIN1,GSTM3,HNF4A,LPO,NAT2 |
| GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | 6.0e-07 | 9.0e-06 | 1813 | 164 | 21 | ADRA1A,CACNB2,CALB2,CHRNA7,CHRNB2,CLSTN3,CX3CR1,CYP46A1,DRD2,DRD4,EPHB2,GRIN1,HAP1,IGSF11,LGMN,NFATC4,NRXN1,PRKCZ,RAB3B,RIMS3,STX1A |
| GO_EMBRYONIC_MORPHOGENESIS | 6.0e-07 | 9.2e-06 | 1813 | 592 | 47 | ACVR2A,AFF3,AHI1,ALX4,ATOH1,ATP8A2,BCL2L11,CHRD,CHRNA10,CYP26B1,DLL4,EIF4A3,EOMES,EPB41L5,EPHB2,EXT1,FGFR1,FGFR2,FRAS1,FREM2,GCM1,GLI1,GRB2,GREM1,GREM2,HESX1,HLX,HNF4A,HOXA1,IRX5,KCNQ4,LRP6,MBP,MESP2,MMP16,MSX2,NTN1,PAX5,POU4F3,RARB,RDH10,SCRIB,SNAI1,SOX4,SPINT1,STK3,TCF7 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 6.0e-07 | 9.2e-06 | 1813 | 432 | 38 | ACTR3C,ADD2,ALOX15,ARHGAP40,BCL2L11,BIK,CAMSAP3,CCL26,CLEC7A,CLU,CORO1A,CRACD,ESAM,FCHSD1,GBP5,GRB2,HCK,IAPP,JAM3,LCMT1,LDLRAD4,MAPK15,MAPRE3,NCK2,NCKAP1L,OPRD1,PRKCZ,PTGER4,SCIN,SPTA1,SPTAN1,SPTB,STX1A,TENM1,TPPP3,TRIM9,TUBB4A,WAS |
| GO_REGULATION_OF_CELL_SIZE | 6.0e-07 | 9.9e-06 | 1813 | 179 | 22 | ARHGAP4,CDKL3,DCC,DRAXIN,ISLR2,IST1,KDM1A,NKX6-1,NTN1,OLFM1,P2RX7,RB1CC1,RND2,SEMA4D,SEMA7A,SHTN1,SLC12A8,TMEM123,TRPV2,VAV1,XK,ZFYVE27 |
| GO_NEUROTRANSMITTER_METABOLIC_PROCESS | 7.0e-07 | 1.1e-05 | 1813 | 152 | 20 | ACHE,CD34,CLEC7A,CLU,CX3CR1,DDC,ENPP6,GAD1,GLDC,JAK2,NOS1,NOS1AP,NOS2,PDE1B,PTGIS,RGN,SDS,SLC6A4,TPH1,TPH2 |
| GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 7.0e-07 | 1.1e-05 | 1813 | 194 | 23 | ACE,ADRA1A,AFAP1L2,BMP6,CD40,CD74,CNTN1,CRLF1,CSF1R,DOK7,FGFR3,GHR,GPRC5B,GREM1,HTR2A,IL11,IL12A,IL23R,JAK2,NEURL1,NOX4,SEMA4D,SRCIN1 |
| GO_PEPTIDYL_CYSTEINE_MODIFICATION | 7.0e-07 | 1.1e-05 | 1813 | 47 | 11 | ACE,GOLGA7,MAP6D1,NOS1,NOS1AP,NOS2,RAB3B,S100A9,ZDHHC11B,ZDHHC15,ZDHHC23 |
| GO_LYMPHOCYTE_MEDIATED_IMMUNITY | 8.0e-07 | 1.1e-05 | 1813 | 351 | 33 | AICDA,AZGP1,C5,CCR6,CD1D,CD40,CD70,CD74,CEACAM1,CLU,CORO1A,CR2,CRTAM,EMP2,GCNT3,HAVCR2,IL12A,IL23R,MYO1G,NECTIN2,P2RX7,PRKCZ,RAET1G,SERPINB9,SH2D1A,SLA2,SLAMF7,SUSD4,ULBP1,ULBP2,ULBP3,VAV1,WAS |
| GO_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION | 8.0e-07 | 1.1e-05 | 1813 | 30 | 9 | GUCY1A1,GUCY1A2,GUCY1B1,MAFA,MT1F,NDNF,NOS1,NOS1AP,NOS2 |
| GO_RECEPTOR_CLUSTERING | 8.0e-07 | 1.2e-05 | 1813 | 57 | 12 | CDH2,FZD9,GRIK5,ITGAL,ITGB7,MAGI2,MESD,NRXN1,NRXN2,PIGR,SCRIB,TMEFF2 |
| GO_CARTILAGE_DEVELOPMENT | 8.0e-07 | 1.2e-05 | 1813 | 210 | 24 | ACVRL1,ANXA9,BARX2,BMP6,BMP8A,CCN3,COMP,CSGALNACT1,FGF18,FGFR1,FGFR3,GDF6,GREM1,IFT80,LRP6,MMP13,MSX2,RARB,RUNX3,SCIN,SNAI1,SOX6,SULF2,VWA2 |
| GO_NEGATIVE_REGULATION_OF_NEURON_DEATH | 8.0e-07 | 1.2e-05 | 1813 | 210 | 24 | AGAP2,CBL,CD34,CORO1A,CRLF1,CX3CR1,DRAXIN,FGF21,FZD9,GABRB2,GRIN1,JAK2,JUN,LGMN,MT1F,NDNF,NES,NFATC4,POU4F1,PRKCG,PTPRZ1,SLC30A10,TIGAR,UNC5B |
| GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | 8.0e-07 | 1.2e-05 | 1813 | 114 | 17 | B3GNT3,B4GALT4,B4GALT5,CHST4,CHST6,CSGALNACT1,CSPG5,FMOD,HYAL4,ITIH5,NDNF,PRELP,SPOCK2,SPOCK3,ST3GAL2,VCAN,XYLT1 |
| GO_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | 8.0e-07 | 1.2e-05 | 1813 | 114 | 17 | AKIRIN1,C5,CALR,CAMK1D,CCN3,CCR6,CD74,CXCR2,DAPK2,DUSP1,FPR2,GREM1,IL12A,JAM3,LGMN,MPP1,NCKAP1L |
| GO_SENSORY_SYSTEM_DEVELOPMENT | 8.0e-07 | 1.2e-05 | 1813 | 369 | 34 | ACHE,ACVRL1,AHI1,ARL6,ATP8A2,BMP6,CELF4,CRB1,CRYBB3,CYP1A1,DLL4,EPHB2,FREM2,GNAT2,IRX5,ITGAM,JUN,LRP6,MYH15,NES,NKD1,PITX2,POU4F1,RAB11FIP4,RARB,RDH10,RORB,SALL2,SDK2,SLC17A8,SLC4A5,TDRD7,TSPAN12,TUB |
| GO_CARBOHYDRATE_HOMEOSTASIS | 8.0e-07 | 1.3e-05 | 1813 | 241 | 26 | ACSM2A,BACE2,CASR,CEBPA,CYB5R4,FAM3B,FFAR2,FGF21,FGFR4,FKBP1B,FOXA1,GRIK5,HNF4A,KCNJ11,LIN28A,NGFR,NOX4,OAS1,PPP1R3G,PTPRN2,PYGL,SLC29A1,SLC2A4,SOX4,SYBU,VSNL1 |
| GO_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY | 9.0e-07 | 1.3e-05 | 1813 | 68 | 13 | ADGRB2,ADGRB3,ADGRL1,AMIGO1,CBLN2,CLSTN3,EPHB2,EPHB3,IL1RAPL1,NRXN1,SEMA4D,SLITRK2,SLITRK3 |
| GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | 9.0e-07 | 1.3e-05 | 1813 | 168 | 21 | AKIRIN1,BCL9,CFL2,COL19A1,CYP26B1,DISP1,EGR2,EOMES,HEYL,HIVEP3,HLX,KLF5,MYH14,MYH15,NEURL1,PAX5,RBM24,RYR1,TLL2,VGLL2,XK |
| GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 9.0e-07 | 1.3e-05 | 1813 | 23 | 8 | CACNA1G,CACNA2D1,CACNB2,HCN2,HCN4,SCN3B,SCN4B,SCN5A |
| GO_LOCOMOTORY_BEHAVIOR | 9.0e-07 | 1.3e-05 | 1813 | 197 | 23 | ADAM22,ALS2,ASTN1,CEND1,CHRNB2,CHRNB4,DRD2,DRD4,GAD1,GNAO1,GPR37,GRIN1,KALRN,KCND2,NKX2-1,NPY1R,OLFM2,OPRD1,OPRK1,PDE1B,PREX2,SLC18A2,SLC4A10 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 9.0e-07 | 1.3e-05 | 1813 | 115 | 17 | ACTN2,ADD2,APC2,BMERB1,CAMSAP3,CFL2,CLEC16A,CRACD,MAP1S,MAP6D1,NES,PLEKHH2,SCIN,SLN,SPTA1,SPTAN1,SPTB |
| GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 9.0e-07 | 1.3e-05 | 1813 | 141 | 19 | ADRA1A,ALS2,ARHGEF10,ARHGEF3,FGD2,FGD5,GPR4,GPR65,KALRN,MCF2L,MCF2L2,P2RY8,PLEKHG1,PLEKHG4B,PREX2,RASGRF1,ROBO1,TNFAIP1,VAV1 |
| GO_PROTEIN_POLYMERIZATION | 9.0e-07 | 1.3e-05 | 1813 | 273 | 28 | ACTR3C,ADD2,ALOX15,ARHGAP40,ARHGAP6,ARL6,CAMSAP3,CCL26,CORO1A,CRACD,ESAM,FCHSD1,FGG,GRB2,HCK,JAK2,MAPRE3,NCK2,NCKAP1L,SCIN,SPTA1,SPTAN1,SPTB,TENM1,TPPP3,TUBB4A,WAS,WASF3 |
| GO_AMINOGLYCAN_METABOLIC_PROCESS | 1.0e-06 | 1.4e-05 | 1813 | 169 | 21 | B3GAT2,B3GNT3,B4GALT4,B4GALT5,CHST4,CHST6,CSGALNACT1,CSPG5,EXT1,FMOD,GPC2,HS6ST1,HYAL4,ITIH5,NDNF,PRELP,SPOCK2,SPOCK3,ST3GAL2,VCAN,XYLT1 |
| GO_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS | 1.0e-06 | 1.4e-05 | 1813 | 169 | 21 | ABCC1,ACSL6,ACSM2A,ALOX15,AVPR1A,CD74,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F22,CYP4F3,CYP4F8,ELOVL4,GGTLC3,OXCT2,PLA2G4A,PTGIS,PTGR1 |
| GO_DRUG_CATABOLIC_PROCESS | 1.0e-06 | 1.5e-05 | 1813 | 142 | 19 | ACHE,ADA2,ALDH3B2,ASRGL1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,GLDC,HBA1,HBE1,HBG2,HP,LPO,NOS1,OXCT2,PXDNL,SDS,TAT |
| GO_ICOSANOID_METABOLIC_PROCESS | 1.0e-06 | 1.5e-05 | 1813 | 116 | 17 | ABCC1,ALOX15,AVPR1A,CD74,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F22,CYP4F3,CYP4F8,GGTLC3,PLA2G4A,PTGIS,PTGR1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | 1.0e-06 | 1.5e-05 | 1813 | 184 | 22 | BMP6,BTN2A2,CD74,CD86,CDH1,CEACAM1,EPB41L5,FGG,FGL1,HAVCR2,HLX,JAK2,MBP,MIA3,PELI1,PLA2G2D,PODXL,PTK2,RUNX3,SH2B3,SPN,ZNF703 |
| GO_NEURON_APOPTOTIC_PROCESS | 1.0e-06 | 1.5e-05 | 1813 | 243 | 26 | AGAP2,BCL2L11,CORO1A,CRLF1,CX3CR1,DRAXIN,FZD9,GABRB2,GRIK5,GRIN1,ITGAM,JAK2,JUN,LGMN,MT1F,NDNF,NES,NFATC4,NGFR,POU4F1,POU4F3,PRKCG,PTPRZ1,SLC30A10,SRPK2,UNC5B |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1.0e-06 | 1.5e-05 | 1813 | 459 | 39 | ACHE,BMP6,C5,CASR,CD34,CD38,CDH1,CHP2,CRTAM,CSF1R,DMAP1,DOC2B,DRD2,FCN1,FFAR2,FGG,HAVCR2,HUWE1,IL33,ITGAM,JAK2,LILRA2,MAPK11,MBP,NKX6-1,OAZ2,P2RX7,PAEP,POSTN,PRKCZ,PSMD9,PTGER4,RAB29,SCAMP5,SOX4,SYBU,TENM1,TMEM30A,VSNL1 |
| GO_PROTEIN_O_LINKED_GLYCOSYLATION | 1.0e-06 | 1.5e-05 | 1813 | 116 | 17 | B3GNT3,B4GALT5,CHST4,GALNT10,GALNT13,GALNT16,GALNT6,GALNT9,GCNT3,GCNT4,LARGE2,MUC20,OGA,POMGNT2,SDF2,ST3GAL2,ST8SIA6 |
| GO_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | 1.1e-06 | 1.6e-05 | 1813 | 104 | 16 | ALS2,CDH2,CDHR3,CLSTN3,CNIH2,DRD2,GRID1,GRIK4,GRIK5,GRIN1,GRM7,HTR2A,MAPK8IP2,NRXN1,SLC17A8,SLC1A4 |
| GO_ADAPTIVE_IMMUNE_RESPONSE | 1.2e-06 | 1.7e-05 | 1813 | 663 | 50 | ADGRE1,AICDA,ALOX15,AZGP1,C5,CAMK4,CCR6,CD1D,CD209,CD3D,CD40,CD6,CD70,CD74,CD86,CEACAM1,CLU,CR2,EMP2,EOMES,FGL1,GCNT3,HAVCR2,HLA-DPB1,HLX,IL12A,IL23R,IL33,ITK,JAK2,JAM3,LAIR1,LAMP3,LILRB5,LY9,MYO1G,NECTIN2,P2RX7,PRKCZ,PRKD2,RNF125,SH2D1A,SLA2,SLAMF7,SPN,SUSD4,TRAC,TRBV9,TXK,WAS |
| GO_ALPHA_AMINO_ACID_CATABOLIC_PROCESS | 1.2e-06 | 1.8e-05 | 1813 | 105 | 16 | ADHFE1,ASRGL1,CRYM,GAD1,GLDC,GLS,GLS2,HAL,HYKK,MAT1A,NOS1,NOS2,OAT,PADI4,SDS,TAT |
| GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 1.2e-06 | 1.8e-05 | 1813 | 376 | 34 | ACVRL1,ADAMTS3,ALS2,BCL2L11,C5,CAMSAP3,CEBPA,CELF4,DSC3,EOMES,EPB41L5,FGFR1,FGFR2,GCM1,GRB2,HEY2,HS6ST1,KPNA7,LMX1B,MED21,MYO18B,NXN,PCDH12,PLCD1,PLPP4,PNLDC1,RDH10,SNAI1,SOX6,SPINT1,ST8SIA6,STK3,TMEM100,VASH2 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 1.2e-06 | 1.8e-05 | 1813 | 410 | 36 | ANXA9,C5,CCN3,CD34,CEACAM1,CST7,DRD2,DUSP1,FGG,FPR2,GREM1,GRIN1,HAVCR2,IL1R2,KLKB1,KNG1,LILRA2,LRFN5,LTF,NRXN1,PLAT,PTGER4,PTGIS,RGMA,RNF125,ROBO1,SAMHD1,SCRIB,SEMA4D,SEMA7A,SERPINB9,SH2B3,SIGLEC11,SMPDL3B,TAFA3,TRAFD1 |
| GO_REGULATION_OF_NEUROTRANSMITTER_SECRETION | 1.2e-06 | 1.8e-05 | 1813 | 105 | 16 | ADRA1A,ASIC1,CACNB2,CHRNB2,CHRNB4,CPLX1,CSPG5,DRD2,GRIK5,HTR2A,MCTP2,P2RY1,PRKCG,RIMS3,STX1A,SYP |
| GO_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | 1.2e-06 | 1.8e-05 | 1813 | 70 | 13 | ADCYAP1R1,ADRA1A,ARHGAP6,AVPR1A,FGFR1,FGFR2,FGFR3,HTR2A,ITK,NMUR1,PRKCZ,PTAFR,TXK |
| GO_SENSORY_PERCEPTION_OF_PAIN | 1.2e-06 | 1.8e-05 | 1813 | 105 | 16 | ASIC3,CCN3,CHRNB2,GRIN1,HTR2A,IAPP,KCND2,NPY1R,OPRD1,OPRK1,P2RX7,P2RY1,PTAFR,SCN3B,TMEM100,TRPA1 |
| GO_SPERMATID_DIFFERENTIATION | 1.2e-06 | 1.7e-05 | 1813 | 157 | 20 | CCR6,CDYL,DDX25,DHH,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,HOOK1,JAM3,NECTIN2,NEURL1,NUP210L,PAEP,PTCHD3,STRBP,TBPL1,TSSK1B |
| GO_EPIDERMIS_DEVELOPMENT | 1.3e-06 | 1.9e-05 | 1813 | 464 | 39 | ALX4,ATOH1,CASP14,CDH3,CNFN,CYP26B1,DSC2,DSC3,DSG3,EDA,FA2H,FGFR1,FGFR2,GLI1,GRHL1,HEY2,HOXB13,KAZN,KLK7,KRT6B,KRT78,KRTAP9-6,LGR5,MSX2,MYCL,PITX2,POU2F3,POU4F3,SCEL,SCRIB,SGPP1,SNAI1,SOSTDC1,SULT2B1,TGM5,TNFRSF19,UGCG,USH2A,WAS |
| GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 1.3e-06 | 1.8e-05 | 1813 | 463 | 39 | A2ML1,C5,CAMSAP3,CNN3,COL4A3,CST7,ELFN1,FKBP1B,GPATCH2,ITIH5,KNG1,LAMP3,LMTK2,LMTK3,LTF,NCKAP1L,NGFR,NOS1,PLIN5,PPP1R14C,PPP1R1C,PRKCZ,PTPRN2,RGN,RIMBP2,RPS6KA3,SEMA4D,SERPINB7,SERPINB9,SFI1,SH3RF2,SPINK13,SPINT1,SPOCK2,SPOCK3,TIMP3,TIMP4,TNNI3,TNNT2 |
| GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 1.3e-06 | 1.8e-05 | 1813 | 216 | 24 | AMER2,ANKRD6,APC2,BICC1,CDH2,DACT3,DRAXIN,GLI1,GREM1,IFT80,IGFBP2,LRP6,MAPK8IP1,MAPK8IP2,NFATC4,NKD1,NXN,PSMD9,RNF43,SCYL2,SHISA2,SOSTDC1,STK3,TLE3 |
| GO_REGULATION_OF_DENDRITE_MORPHOGENESIS | 1.3e-06 | 1.8e-05 | 1813 | 93 | 15 | ADGRB3,ARHGAP44,CAMK2B,CDKL3,CHRNB2,FBXO31,GRIN1,IL1RAPL1,KALRN,KNDC1,LZTS1,NEDD4L,NFATC4,SEMA4D,SRCIN1 |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 1.4e-06 | 1.9e-05 | 1813 | 704 | 52 | ACTN2,ADCY4,ATP1A3,ATP6V0B,ATP6V1C2,AVPR1A,BCL2L11,CALR,CEACAM1,CHRM4,CHRNA7,CHRNB2,DUSP1,ENHO,ESRRB,FGF21,FOXA1,GHR,GRB2,HEYL,HNF4A,IGFBP2,INHBB,JAK2,JUN,LGR5,MSX2,NKX3-1,NKX6-1,NPFFR1,NPFFR2,NR2C1,NR2F1,NR5A2,NR6A1,POU4F1,PRKAR2B,PRKCZ,PTGER4,PTK2,RARB,RGS10,RORB,SLC2A4,SLC30A10,SLC5A5,SLIT3,SSTR2,SYAP1,UGCG,VWA2,ZNF703 |
| GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS | 1.4e-06 | 2.0e-05 | 1813 | 145 | 19 | ACER2,ACER3,ALDH3B2,B4GALT5,ELOVL4,FA2H,ORMDL3,P2RX7,PLPP2,PPM1L,PRKD2,SGPP1,ST3GAL2,ST3GAL5,ST8SIA1,ST8SIA6,TLCD3B,UGCG,UGT8 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 1.4e-06 | 2.0e-05 | 1813 | 860 | 60 | BARX2,BCL11A,BMP6,CALR,CEBPA,CIITA,CPEB3,CRYM,DLL4,DLX4,DMAP1,DMRT1,DUSP26,EOMES,ETV3,ETV7,FGFR1,FGFR2,FOXA1,GLIS3,HES2,HESX1,HEY2,HEYL,HOXB13,IKZF5,JUN,KDM1A,KLF5,MAPK10,MSX2,NCK2,NEDD4L,NFATC4,NFE2L3,NKX2-1,NKX6-1,NOTCH3,NPAS1,NR2C1,NR2F1,NR6A1,PAX5,POU4F1,RARB,RITA1,RUNX3,SALL2,SEMA4D,SLA2,SNAI1,SNAI3,SOX6,SP5,SPDEF,TCF7,TFCP2L1,UBE2D1,ZGPAT,ZNF431 |
| GO_NEUROTRANSMITTER_BIOSYNTHETIC_PROCESS | 1.4e-06 | 2.0e-05 | 1813 | 106 | 16 | ACHE,CD34,CLEC7A,CLU,CX3CR1,DDC,GAD1,JAK2,NOS1,NOS1AP,NOS2,PTGIS,RGN,SLC6A4,TPH1,TPH2 |
| GO_MEMORY | 1.5e-06 | 2.1e-05 | 1813 | 119 | 17 | ASIC1,BRINP1,CAMK4,CHRNA7,CHRNB2,CPEB3,CX3CR1,DRD2,GRIN1,HTR2A,KALRN,KCNK2,LGMN,NFATC4,PRKCZ,RASGRF1,SLC6A4 |
| GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | 1.5e-06 | 2.0e-05 | 1813 | 94 | 15 | ACE,ADRA1A,AVPR1A,CORIN,CYP4F12,DRD2,EMP2,GPR37L1,HSD11B2,KLK1,NCALD,PCSK5,POSTN,SLC4A5,TNNI3 |
| GO_PROTEIN_LOCALIZATION_TO_SYNAPSE | 1.6e-06 | 2.3e-05 | 1813 | 83 | 14 | ADAM22,ARHGAP44,CACNG7,CLSTN3,CNIH2,CPLX1,GRIN1,KIF5A,KIF5C,MAPK10,NRXN1,NRXN2,PRKCZ,SCRIB |
| GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 1.7e-06 | 2.3e-05 | 1813 | 120 | 17 | AFAP1L2,CBL,CEACAM1,GAREM1,GRB2,HAP1,NCK2,NEURL1,PIGR,PTK2,PTPN3,REPS2,SHKBP1,SLC30A10,SOCS4,STAM2,ZGPAT |
| GO_IMPORT_ACROSS_PLASMA_MEMBRANE | 1.7e-06 | 2.3e-05 | 1813 | 120 | 17 | ATP1A3,ATP1B1,ATP1B2,CACNA2D1,FAM155A,HCN2,HCN4,KCNH2,KCNJ11,KCNJ12,KCNJ15,KCNJ5,KCNJ6,KCNK5,KCNK9,SLC12A8,SLC1A6 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 1.7e-06 | 2.4e-05 | 1813 | 469 | 39 | BTN2A2,C1QL4,CADM4,CBL,CDKN2A,CEACAM1,CEBPA,CHRNA10,DRD2,DUSP1,DUSP26,DUSP9,DYNLL1,EPHB2,GFRA2,GREM1,GSKIP,JUN,KIRREL2,KLHL31,LDLRAD4,LRP6,MAPK8IP1,NCK2,NDRG2,P2RX7,PRKAR2B,PRKCZ,RGN,SEMA4D,SH2B3,SH3RF2,SOCS4,SRCIN1,TESC,TIGAR,TIMP3,VRK3,ZGPAT |
| GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | 1.7e-06 | 2.4e-05 | 1813 | 51 | 11 | AZGP1,CD1D,CRTAM,IL12A,IL23R,ITGAM,NECTIN2,NOS2,P2RX7,SH2D1A,VAV1 |
| GO_REGULATION_OF_REPRODUCTIVE_PROCESS | 1.7e-06 | 2.4e-05 | 1813 | 161 | 20 | ACVR1C,CALR,CCR6,DMRT1,DUSP1,EAF2,GCM1,GDF9,INHBB,MAPK15,MSX2,NKX3-1,NOX5,P2RY1,PAEP,PTAFR,RGN,SNAI1,SPINK13,STK3 |
| GO_RESPONSE_TO_ANTIBIOTIC | 1.7e-06 | 2.4e-05 | 1813 | 331 | 31 | ADCYAP1R1,AHR,AOC1,CBL,CHRNB2,CIITA,CLU,CYB5R4,CYBB,CYP1A1,DMAP1,DRD2,DRD4,DUSP1,FGFR2,FKBP1B,GNAO1,GPR37,GPR37L1,GRIN1,HBA1,HP,HTR3A,JAK2,JUN,KCNMB1,KDM1A,PLA2G4A,SLC2A4,STK26,TRPA1 |
| GO_RESPONSE_TO_CALCIUM_ION | 1.7e-06 | 2.4e-05 | 1813 | 147 | 19 | ALOX15,CASR,CHP2,CPNE4,DUSP1,FGG,JUN,KCNMB1,LGMN,P2RX7,RYR1,RYR3,SCN5A,SLC6A1,SYT13,SYT2,SYT5,TNNT2,TPH2 |
| GO_MICROTUBULE_BASED_MOVEMENT | 1.9e-06 | 2.6e-05 | 1813 | 283 | 28 | AP3B2,BICDL1,BICDL2,CAMSAP3,CFAP53,CFAP61,CNIH2,DNAH12,DNAH2,DNAH7,DNAI1,DYNLL1,HAP1,HYDIN,IFT20,IFT80,KIF13A,KIF13B,KIF21B,KIF27,KIF5A,KIF5C,KLC3,MAP1S,PRKCZ,SYBU,TEKT1,TUB |
| GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 1.9e-06 | 2.6e-05 | 1813 | 96 | 15 | AKAP6,ATP1B1,CACNA2D1,CACNB2,DRD2,DRD4,FGF14,FKBP1B,GEM,HAP1,MRLN,NOS1,NOS1AP,RGN,SLN |
| GO_REGULATION_OF_PRESYNAPSE_ORGANIZATION | 1.9e-06 | 2.5e-05 | 1813 | 33 | 9 | CBLN2,CLSTN3,IL1RAPL1,LRFN5,MDGA1,NRXN1,NTNG2,SLITRK2,SLITRK3 |
| GO_CELLULAR_RESPONSE_TO_DRUG | 2.0e-06 | 2.7e-05 | 1813 | 436 | 37 | ACER2,AHR,AMIGO1,AOC1,BCL11A,CDH1,CHRM4,CHRNA7,CHRNB2,CYBB,DDC,DRD2,DRD4,FGF21,GNAL,GNAO1,GPR37,GPR37L1,GUCY1B1,HTR2A,HTR3A,HTR3B,KCNC1,KCNH2,KCNJ11,KCNMB1,MAP4K1,NKX3-1,NOS2,P2RX7,P2RY1,PTAFR,RGS10,RGS9,RYR1,RYR3,STK26 |
| GO_CYTOKINE_SECRETION | 2.0e-06 | 2.7e-05 | 1813 | 252 | 26 | BTN2A2,C5,CARD11,CD34,CRTAM,CSF1R,DRD2,FCN1,FFAR2,GBP5,HAVCR2,IL1R2,IL33,LILRA2,MAPK11,MBP,NOS2,NOX5,P2RX7,PAEP,POSTN,PRKCZ,PTGER4,SCAMP5,TLR10,TLR5 |
| GO_GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS | 2.0e-06 | 2.8e-05 | 1813 | 73 | 13 | ADHFE1,ASRGL1,GAD1,GLS,GLS2,HAL,NOS1,NOS2,NOXRED1,OAT,PADI4,SIRT4,TAT |
| GO_POSITIVE_REGULATION_OF_CHEMOTAXIS | 2.0e-06 | 2.8e-05 | 1813 | 135 | 18 | AKIRIN1,CALR,CAMK1D,CASR,CCL26,CCR6,CD74,CXCR2,DAPK2,FGF18,FGFR1,FPR2,IL12A,IL16,LGMN,NCKAP1L,PRKD2,SCG2 |
| GO_RESPONSE_TO_ESTRADIOL | 2.0e-06 | 2.8e-05 | 1813 | 135 | 18 | ADCYAP1R1,BCL2L11,CALR,CD38,CYP1A2,DHH,DUSP1,FOXA1,IGFBP2,KCNJ11,MSX2,POSTN,POU4F1,RGS9,SLC6A1,SLC6A4,SSTR2,ZNF703 |
| GO_GLAND_MORPHOGENESIS | 2.1e-06 | 2.8e-05 | 1813 | 122 | 17 | BTRC,CEACAM1,CSF1R,EDA,FGFR1,FGFR2,FGL1,FOXA1,GLI1,HOXB13,LRP6,MSX2,NKX3-1,NTN1,SCRIB,SOSTDC1,SULF2 |
| GO_REGULATION_OF_PROTEOLYSIS | 2.2e-06 | 3.0e-05 | 1813 | 735 | 53 | A2ML1,ACER2,ACVR1C,ANXA9,BCL2L11,BTRC,C5,CASP14,CEBPA,CLEC16A,CLEC7A,CLU,COL4A3,CST7,CYFIP2,DAPK1,DNAJC1,FGFR4,GRIN1,IL1R2,IL33,IST1,ITIH5,JAK2,KLKB1,KNG1,LAMP3,LGMN,LTF,MBP,NGFR,NKX3-1,PLAT,PRKCG,PTK2,PTPN3,RGN,ROBO1,RPS6KA3,S100A9,SERPINB7,SERPINB9,SH3RF2,SIRT4,SOCS4,SPINK13,SPINT1,SPOCK2,SPOCK3,TIMP3,TIMP4,TNFSF10,TNFSF15 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 2.3e-06 | 3.1e-05 | 1813 | 603 | 46 | BCL2L11,BIK,CASP14,CD38,CD70,CD74,CLU,CX3CR1,DAPK1,DAPK2,DAPL1,DCC,FGFR1,FGFR3,FGG,FZD9,GSKIP,HIGD1A,IL12A,IL33,IL7,INHBB,ITGA6,ITGAM,ITM2C,JAK2,JUN,KDM1A,MAPK8IP1,MAPK8IP2,NCK2,NFATC4,NKX3-1,P2RX7,POU4F1,PTGIS,RB1CC1,S100A9,SCG2,SEPTIN4,SGPP1,SNAI1,STK3,TIMP3,TNFSF10,UNC5B |
| GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS | 2.3e-06 | 3.1e-05 | 1813 | 270 | 27 | ACER2,ACER3,ADCYAP1R1,AKR1D1,ALOX15,BMP6,CDH3,CYB5R1,CYP26B1,CYP27A1,CYP39A1,CYP46A1,DDC,FGFR4,GPR37,MALRD1,OSBPL6,P2RY1,PLCD1,PLCH1,PLCL2,PPIP5K1,PTAFR,SNAI1,SRD5A2,TPH1,TPH2 |
| GO_REGULATION_OF_POTASSIUM_ION_TRANSPORT | 2.3e-06 | 3.1e-05 | 1813 | 110 | 16 | ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,DRD2,HTR2A,KCNC1,KCNE5,KCNH2,KCNIP4,KCNMB1,KCNN2,NEDD4L,NOS1,NOS1AP |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_PROCESS | 2.4e-06 | 3.2e-05 | 1813 | 63 | 12 | CHRNA7,CHRNB4,CST7,GRIN1,IGSF11,ITGAX,MYRF,NRXN1,PRKCZ,PTAFR,STX1A,WASF3 |
| GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | 2.4e-06 | 3.1e-05 | 1813 | 123 | 17 | CD34,CLEC7A,CLU,CX3CR1,CYBB,CYP1A1,CYP1A2,GRIN1,JAK2,NOS1,NOS1AP,NOS2,NOX4,PTGIS,RGN,SLC18A2,SLC30A10 |
| GO_GERM_CELL_DEVELOPMENT | 2.5e-06 | 3.3e-05 | 1813 | 255 | 26 | CCR6,CDYL,CELF4,DDX25,DHH,DMRT1,DPY19L2,DPY19L2P1,DPY19L2P2,FAM9A,FAM9B,FSCN3,GDF9,HOOK1,INHBB,JAM3,LGR5,LIN28A,NECTIN2,NEURL1,NUP210L,PAEP,PTCHD3,STRBP,TBPL1,TSSK1B |
| GO_LEUKOCYTE_CHEMOTAXIS | 2.5e-06 | 3.3e-05 | 1813 | 224 | 24 | AKIRIN1,C5,CALR,CAMK1D,CCL26,CCN3,CCR6,CD74,CORO1A,CXCR2,DAPK2,DUSP1,FFAR2,FPR2,GREM1,IL12A,IL16,JAM3,LGMN,MPP1,NCKAP1L,S100A9,SCG2,VAV1 |
| GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 2.5e-06 | 3.3e-05 | 1813 | 549 | 43 | ACE,ADA2,AOC1,ARHGAP9,CBL,CEACAM1,CHRNB4,CXCR2,CYBB,DYNLL1,FCN1,FPR2,FRMPD3,GCA,GOLGA7,HP,HUWE1,HVCN1,IST1,ITGAL,ITGAM,ITGAX,LAIR1,LTF,MAGT1,MGAM,NCKAP1L,NFASC,ORMDL3,PIGR,PTAFR,PTPRN2,PYGL,RAB37,RAB44,RAB9B,S100A9,SELL,SERPINB9,SIGLEC14,SPTAN1,TMC6,TMEM30A |
| GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | 2.5e-06 | 3.3e-05 | 1813 | 34 | 9 | ATP1B1,ATP1B2,CNTN1,DRD4,NOS1,SCN3B,SCN4B,SCN5A,TESC |
| GO_PROTEIN_DEPHOSPHORYLATION | 2.5e-06 | 3.3e-05 | 1813 | 320 | 30 | BTRC,CDC14A,CNEP1R1,CTTNBP2NL,DRD2,DUSP1,DUSP26,DUSP9,ELFN1,FKBP1B,JAK2,LMTK2,MAGI2,NCKAP1L,PLPP2,PPM1J,PPM1L,PPP1R14C,PPP1R16B,PPP1R1C,PPP2R2C,PPP6C,PTPN3,PTPRN2,PTPRZ1,RGN,SBF1,SH3RF2,SYMPK,VRK3 |
| GO_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | 2.5e-06 | 3.3e-05 | 1813 | 43 | 10 | CACNA1G,CACNA1I,CDK5R2,DOC2B,SCAMP5,STX1A,SYT13,SYT2,SYT5,TRIM9 |
| GO_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | 2.5e-06 | 3.3e-05 | 1813 | 86 | 14 | CDH2,CEND1,CX3CR1,DISP3,DLL4,DRD2,FZD9,GLI1,GPR37L1,KDM1A,NES,PTPRZ1,SLC6A4,SPINT1 |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 2.7e-06 | 3.5e-05 | 1813 | 372 | 33 | ACSL6,ACSM2A,ACSM3,B3GNT3,B4GALT4,B4GALT5,CHST4,CHST6,CSGALNACT1,CSPG5,ELOVL4,FMOD,GGTLC3,GHR,GPAT4,GSTM3,HYAL4,LPO,MAT1A,MTAP,NDNF,NOX4,PRELP,SPOCK2,SPOCK3,ST3GAL2,SULT2B1,SULT4A1,THEM4,TPST1,TSTD1,VCAN,XYLT1 |
| GO_DETECTION_OF_ABIOTIC_STIMULUS | 2.8e-06 | 3.7e-05 | 1813 | 138 | 18 | ANO3,ASIC3,ATP8A2,CHRNA10,CNGA1,CNGB1,ELOVL4,GNAT2,GUCA1B,GUCA1C,HTR2A,NMT2,NPFFR2,PKD1L2,PLEKHB1,SEMA5B,TRPA1,TRPM8 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 2.8e-06 | 3.7e-05 | 1813 | 75 | 13 | ADD2,APC2,BMERB1,CAMSAP3,CLEC16A,CRACD,MAP6D1,PLEKHH2,SCIN,SLN,SPTA1,SPTAN1,SPTB |
| GO_ACID_SECRETION | 3.0e-06 | 3.9e-05 | 1813 | 125 | 17 | ACE,AVPR1A,CASR,CPLX1,DRD2,DRD4,GLS,GLS2,GRM7,MAP2K6,NOS2,P2RX7,PLA2G2D,PLA2G4A,SLC1A6,SLC6A1,STX1A |
| GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | 3.0e-06 | 3.9e-05 | 1813 | 181 | 21 | AP3B2,BICDL1,BICDL2,CAMSAP3,CNIH2,DYNLL1,HAP1,HOOK1,IFT20,IFT80,KIF13A,KIF5A,KIF5C,KLC3,MAP1S,MAP6,MAP6D1,MYO10,PRKCZ,SYBU,TUB |
| GO_RESPONSE_TO_OXYGEN_LEVELS | 3.0e-06 | 3.9e-05 | 1813 | 391 | 34 | ACVRL1,ATP1B1,CASR,CBL,CD34,CD38,CHRNA7,CHRNB2,CYB5R4,CYBB,CYP1A1,DRD2,HIGD1A,HSD11B2,KCND2,KCNK2,KCNMB1,NDNF,NKX3-1,NOS1,NOS2,NOX4,OPRD1,PLAT,POSTN,PSMD9,PTGIS,RYR1,SCFD1,SIRT4,SLC29A1,SLC2A4,SLC6A4,TIGAR |
| GO_MONOCARBOXYLIC_ACID_TRANSPORT | 3.1e-06 | 4.0e-05 | 1813 | 167 | 20 | ACE,CASR,CEACAM1,CPT1A,DRD2,DRD4,MAP2K6,NOS2,P2RX7,PLA2G2D,PLA2G4A,SLC16A10,SLC16A2,SLC16A5,SLC27A6,SLC6A1,SLC6A11,SLC6A12,SLC6A13,SLCO2B1 |
| GO_PROTEIN_KINASE_B_SIGNALING | 3.1e-06 | 4.0e-05 | 1813 | 274 | 27 | BTN2A2,CD40,CD86,CX3CR1,DRD2,FGF18,FGFR1,FGFR2,FGFR3,FGFR4,GRB2,IAPP,LIN28A,MAGI2,NKX3-1,NOX4,NRG2,OTUD3,PIK3AP1,PIK3C2B,PIK3R5,PTK2,SH2B3,STK3,THEM4,TMEM100,VAV1 |
| GO_SENSORY_ORGAN_MORPHOGENESIS | 3.1e-06 | 4.0e-05 | 1813 | 258 | 26 | AHI1,ARL6,ATOH1,ATP8A2,CHRNA10,CRB1,CYP26B1,EPHB2,FGFR1,FGFR2,GNAT2,HESX1,HOXA1,IRX5,KCNQ4,LRP6,NKD1,NTN1,PITX2,POU4F3,RARB,RORB,SCRIB,SDK2,TDRD7,TSPAN12 |
| GO_WOUND_HEALING | 3.1e-06 | 4.0e-05 | 1813 | 572 | 44 | ACVRL1,AKIRIN1,ALOX15,ANXA9,BCL9,CADM4,CCN3,CD34,CD40,CDH3,CEACAM1,CLEC7A,COMP,DOCK8,F5,FGFR1OP2,FGFR2,FGG,FZD9,GPR4,HBE1,HBG2,HNF4A,JAK2,KDM1A,KLF5,KLKB1,KNG1,MIA3,MSX2,NDNF,P2RX7,P2RY1,PIK3R5,PLAT,POSTN,PRKAR2B,PRKCG,SCRIB,SCUBE1,SH2B3,TMEFF2,VAV1,WAS |
| GO_HEART_MORPHOGENESIS | 3.3e-06 | 4.3e-05 | 1813 | 259 | 26 | ACVRL1,AHI1,DLL4,EOMES,FGFR2,HEY2,HEYL,JUN,MESP2,MSX2,MYL2,NPY1R,NRP2,OLFM1,PITX2,POU4F1,PTK2,RARB,ROBO1,RYR1,SLIT3,SNAI1,SOX4,TMEM100,TNNI3,TNNT2 |
| GO_POSITIVE_REGULATION_OF_AXONOGENESIS | 3.4e-06 | 4.3e-05 | 1813 | 88 | 14 | AMIGO1,CHODL,ISLR2,IST1,MAP6,NGFR,NTN1,RND2,ROBO1,SEMA4D,SEMA7A,SHTN1,TRPV2,ZFYVE27 |
| GO_POSTSYNAPSE_ORGANIZATION | 3.4e-06 | 4.4e-05 | 1813 | 168 | 20 | ARHGAP44,CAMK2B,CDH2,CHRNA7,CRIPT,EPHB2,EPHB3,FZD9,IL1RAPL1,KALRN,LGMN,LRFN1,MAGI2,MESD,NOS1AP,NRP2,NRXN1,NRXN2,NTNG2,SRCIN1 |
| GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 3.5e-06 | 4.5e-05 | 1813 | 394 | 34 | ADD2,AICDA,APC2,ARHGAP6,BMERB1,CAMSAP3,CLEC16A,CLU,CORO1A,CRACD,DMRT1,DUSP1,FZD9,HIGD1A,IAPP,IQCJ-SCHIP1,KDM1A,LCMT1,MAP6D1,PAX5,PLEKHH2,SCFD1,SCIN,SEC22B,SIRT4,SPTA1,SPTAN1,SPTB,TBC1D30,TIGAR,TMEFF2,TRIM9,TUBB4A,WAS |
| GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 3.5e-06 | 4.5e-05 | 1813 | 213 | 23 | AZGP1,CD1D,CD40,CD74,CD86,CRTAM,FFAR2,GPRC5B,HLX,IL12A,IL23R,IL33,ITGAM,KLK7,NECTIN2,P2RX7,PRKCZ,PTAFR,RAET1G,SCIMP,SEMA7A,SH2D1A,VAV1 |
| GO_EPITHELIAL_TUBE_MORPHOGENESIS | 3.8e-06 | 4.9e-05 | 1813 | 327 | 30 | ACVRL1,AHI1,BTRC,CASR,CSF1R,CXCR2,DLL4,EOMES,FGFR2,FOXA1,GREB1L,GREM1,HESX1,ITGAX,KIF26B,LGR5,LRP6,MSX2,NFATC4,NKX2-1,NKX3-1,NTN1,PODXL,PRKD2,RDH10,SCRIB,SOSTDC1,SOX4,SPINT1,STK3 |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION | 3.8e-06 | 4.9e-05 | 1813 | 141 | 18 | C5,CD34,CRTAM,CSF1R,DRD2,FCN1,FFAR2,HAVCR2,IL33,LILRA2,MAPK11,MBP,P2RX7,PAEP,POSTN,PRKCZ,PTGER4,SCAMP5 |
| GO_REGULATION_OF_PHOSPHOLIPASE_C_ACTIVITY | 3.8e-06 | 4.9e-05 | 1813 | 45 | 10 | ADCYAP1R1,ADRA1A,ARHGAP6,AVPR1A,FGFR1,HTR2A,ITK,NMUR1,PTAFR,TXK |
| GO_SYNAPTIC_TRANSMISSION_GABAERGIC | 3.8e-06 | 4.9e-05 | 1813 | 45 | 10 | ADRA1A,CLSTN3,DRD2,GABRA1,GABRA6,GABRB2,HAP1,PLCL2,SLC6A1,SYN3 |
| GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 3.9e-06 | 4.9e-05 | 1813 | 89 | 14 | ACE,ADRA1A,AFAP1L2,CBL,CSF1R,DOK7,GPRC5B,GREM1,NCK2,NEURL1,NOX4,SOCS4,SRCIN1,ZGPAT |
| GO_CALCIUM_ION_REGULATED_EXOCYTOSIS | 4.0e-06 | 5.1e-05 | 1813 | 66 | 12 | CACNA1G,CACNA1I,CDK5R2,DOC2B,RIMS3,SCAMP5,SCIN,STX1A,SYT13,SYT2,SYT5,TRIM9 |
| GO_POSITIVE_REGULATION_OF_HORMONE_SECRETION | 4.1e-06 | 5.2e-05 | 1813 | 128 | 17 | BMP6,CASR,CD38,DOC2B,DRD2,FGFR1,FGG,ILDR1,INHBB,JAK2,NKX3-1,NKX6-1,P2RY1,PSMD9,SOX4,SYBU,VSNL1 |
| GO_VIRAL_LIFE_CYCLE | 4.1e-06 | 5.2e-05 | 1813 | 328 | 30 | AICDA,CD209,CD74,CD86,CDHR3,CR2,FCN1,HTR2A,IST1,ITGB7,KPNA1,LAMP3,LRRC15,LTF,MRC1,NCAM1,NECTIN2,NEDD4L,NMT2,NR5A2,OAS1,OASL,PCSK5,RAB29,SELPLG,SRPK2,TMPRSS2,UBAP1,USP6NL,XPR1 |
| GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS | 4.2e-06 | 5.3e-05 | 1813 | 200 | 22 | ADHFE1,ASRGL1,AZIN2,CRYM,GAD1,GLDC,GLS,GLS2,HAL,HNF4A,HYKK,MAT1A,MTAP,NOS1,NOS2,NOX4,NOXRED1,OAT,PADI4,SDS,SIRT4,TAT |
| GO_FATTY_ACID_METABOLIC_PROCESS | 4.2e-06 | 5.3e-05 | 1813 | 380 | 33 | ABHD5,ACSL6,ACSM2A,ACSM3,ALOX15,AVPR1A,CD74,CEACAM1,CPT1A,CPT1C,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F3,CYP4F8,ELOVL4,ETFBKMT,FA2H,FADS6,GPAT4,PLA2G4A,PLIN5,PLP1,PRKAR2B,PTGIS,PTGR1,RGN,SIRT4,SLC27A6,THEM4 |
| GO_NEGATIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 4.2e-06 | 5.3e-05 | 1813 | 142 | 18 | ADD2,APC2,ARHGAP6,BMERB1,CAMSAP3,CLU,CORO1A,CRACD,IAPP,MAP6D1,PLEKHH2,SCIN,SPTA1,SPTAN1,SPTB,TMEFF2,TUBB4A,WAS |
| GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | 4.4e-06 | 5.5e-05 | 1813 | 78 | 13 | ADRA1A,CACNB2,CHRNB2,CPLX1,CSPG5,DRD2,GRIK5,HTR2A,P2RY1,PRKCG,RIMS3,STX1A,SYP |
| GO_CILIUM_ORGANIZATION | 4.5e-06 | 5.6e-05 | 1813 | 381 | 33 | AHI1,ARL6,CDC14A,CEP19,CEP83,CFAP53,CFAP61,DCDC2,DNAAF3,DNAH7,DNAI1,DYNLL1,GFY,HAP1,HYDIN,IFT20,IFT80,IQUB,JHY,KCTD17,KIF27,LRGUK,MAPK15,NECTIN2,NEURL1,PRKAR2B,RAB17,SEPTIN6,SFI1,TBC1D30,TEKT1,TUB,TUBB4A |
| GO_PROTEIN_PROCESSING | 4.5e-06 | 5.6e-05 | 1813 | 216 | 23 | ACE,ADAMTS3,ANXA9,BACE2,COMP,CORIN,CPM,CPZ,CST7,CYFIP2,FGG,IL1R2,KLK1,KLKB1,LGMN,MMP16,MYRF,P2RX7,PCSK2,PCSK5,PLAT,SIRT4,TMPRSS2 |
| GO_REGULATION_OF_PROTEIN_POLYMERIZATION | 4.5e-06 | 5.6e-05 | 1813 | 216 | 23 | ACTR3C,ADD2,ALOX15,ARHGAP40,CAMSAP3,CCL26,CORO1A,CRACD,ESAM,FCHSD1,GRB2,HCK,MAPRE3,NCK2,NCKAP1L,SCIN,SPTA1,SPTAN1,SPTB,TENM1,TPPP3,TUBB4A,WAS |
| GO_ACIDIC_AMINO_ACID_TRANSPORT | 4.7e-06 | 5.9e-05 | 1813 | 67 | 12 | AVPR1A,CPLX1,GLS,GLS2,GRM7,LRRC8C,LRRC8E,P2RX7,SLC17A8,SLC1A6,SLC6A1,STX1A |
| GO_LIPID_TRANSLOCATION | 4.7e-06 | 5.9e-05 | 1813 | 46 | 10 | ABCB1,ABCC1,ANO3,ANO9,ATP8A2,P2RX7,SLC66A2,TMEM30A,XKR4,XKR5 |
| GO_NEUROTRANSMITTER_UPTAKE | 4.7e-06 | 5.9e-05 | 1813 | 46 | 10 | DRD2,DRD4,NOS1,RAB3B,SLC18A2,SLC1A6,SLC29A1,SLC6A1,SLC6A11,SLC6A4 |
| GO_ORGANELLE_ASSEMBLY | 4.9e-06 | 6.1e-05 | 1813 | 835 | 57 | ACTN2,AHI1,ARHGEF10,ARL6,CD34,CDC14A,CEP19,CEP83,CFAP53,CFL2,CORO1A,DCDC2,DNAAF3,DNAH7,DNAI1,DYNLL1,GFY,HAP1,HCK,HYDIN,IFT20,IFT80,IQUB,IST1,JHY,KCTD17,KIF27,LRFN1,LRGUK,MAPK15,MAPRE3,MYL2,NECTIN2,NEURL1,NRXN1,NRXN2,NTNG2,P2RX7,PIP4K2A,PLS1,PRKAR2B,RAB17,RB1CC1,RPL3L,SCFD1,SEC22B,SEPTIN6,SFI1,STAM2,STX12,TBC1D30,TBPL1,TEKT1,TMEM41B,TNNT2,TUBB4A,VMP1 |
| GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 4.9e-06 | 6.1e-05 | 1813 | 202 | 22 | CLEC7A,FCN1,FFAR2,FGG,HAVCR2,ITGAM,LGMN,LILRA2,LTF,MAP2K6,PELI1,PIK3AP1,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SMPDL3B,TLR10,TLR5,TLR7,UBE2D1 |
| GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT | 5.1e-06 | 6.3e-05 | 1813 | 79 | 13 | B4GALT5,CHRNB2,DCC,DCLK1,DRD2,EPHB2,EPHB3,FGFR2,LHX6,NRP2,PTK2,ROBO1,SLC4A10 |
| GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 5.3e-06 | 6.5e-05 | 1813 | 455 | 37 | AZGP1,C5,CD1D,CD22,CD40,CD74,CD86,CEACAM1,CFHR1,CLU,CR2,CRTAM,FFAR2,GPRC5B,HAVCR2,HERC5,HLX,IFNLR1,IL12A,IL23R,IL33,ITGAM,KLK7,NECTIN2,P2RX7,PRKCZ,PTAFR,RAET1G,RNF125,RNF216,SCIMP,SEMA7A,SERPINB9,SH2D1A,SUSD4,VAV1,WAS |
| GO_ORGAN_GROWTH | 5.4e-06 | 6.6e-05 | 1813 | 203 | 22 | ADRA1A,AKAP6,ANXA9,BCL2L11,CACNA2D2,COMP,FGFR1,FGFR2,FGFR3,GLI1,HEY2,HLX,IL7,KCNK2,MAPK11,MMP13,MSX2,PTK2,RARB,SLC6A4,STK3,VWA2 |
| GO_NEGATIVE_REGULATION_OF_CELL_MOTILITY | 5.5e-06 | 6.8e-05 | 1813 | 350 | 31 | ABHD6,ACVR1C,ACVRL1,ARHGAP4,BMERB1,C5,CALR,CCN3,CD74,CDH1,CHRD,CX3CR1,DLL4,DPYSL3,DRD2,DUSP1,GREM1,IL33,LDLRAD4,MAGI2,MAPK15,MIA3,NKX2-1,PTGER4,RGN,ROBO1,SPOCK3,SRGAP3,STK26,TMEFF2,WAS |
| GO_CELL_CELL_JUNCTION_ASSEMBLY | 5.6e-06 | 6.9e-05 | 1813 | 131 | 17 | ACE,CDH1,CDH15,CDH2,CDH3,CDHR3,ESAM,GPBAR1,JAM3,LSR,NFASC,OCLN,PARD6G,SNAI1,TJP1,UGT8,ZNF703 |
| GO_LEARNING | 5.7e-06 | 7.0e-05 | 1813 | 145 | 18 | ADGRB3,ASIC1,CHRNB2,DRD2,EIF4A3,EPHB2,GRIN1,IFT20,JUN,KALRN,LGMN,MAPK8IP2,NRXN1,NRXN2,NRXN3,PDE1B,PRKAR2B,SLC6A1 |
| GO_POSITIVE_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 5.7e-06 | 7.0e-05 | 1813 | 145 | 18 | ADCYAP1R1,AVPR1A,BMP6,CD74,CPT1A,ESRRB,GUCA1B,GUCA1C,HTR2A,NOS1,NOS2,P2RX7,P2RY1,PLIN5,PPP1R3G,PTAFR,RDH10,RGN |
| GO_CELL_MATURATION | 5.8e-06 | 7.1e-05 | 1813 | 174 | 20 | ADGRB3,B4GALT5,BCL11A,CCR6,CEBPA,CLEC7A,FGFR1,FGG,FOXA1,GPAT4,HOXB13,IRX5,KDM1A,L3MBTL3,LHX6,NFASC,NKX6-1,PAEP,SRRM4,TFCP2L1 |
| GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT | 5.8e-06 | 7.1e-05 | 1813 | 47 | 10 | ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,KCNC1,KCNE5,KCNH2,KCNMB1,NOS1AP |
| GO_RESPONSE_TO_AMINE | 5.8e-06 | 7.1e-05 | 1813 | 47 | 10 | ASIC1,DRD2,DRD4,GLDC,GRIN1,KCNC1,PDE1B,RGS10,RGS9,SLC18A2 |
| GO_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | 6.0e-06 | 7.3e-05 | 1813 | 105 | 15 | CDH3,CHRNB2,CRYM,DDC,DRD2,DRD4,GCNT4,GPR37,ITGAM,PDE1B,SLC16A10,SLC16A2,SLC5A5,TPH1,TPH2 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 6.1e-06 | 7.5e-05 | 1813 | 440 | 36 | ADA2,ADHFE1,AICDA,AKR1D1,ALDH3B2,ASRGL1,CPT1A,CPT1C,CRYM,CYP1A1,CYP26B1,CYP27A1,CYP39A1,CYP46A1,CYP4F12,CYP4F3,ENTPD3,ETFBKMT,GAD1,GALM,GLDC,GLS,GLS2,HAL,HYKK,MAT1A,MIOX,NOS1,NOS2,OAT,OXCT2,PADI4,PLIN5,SDS,TAT,TIGAR |
| GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 6.2e-06 | 7.6e-05 | 1813 | 335 | 30 | AMIGO1,AOC1,ASGR1,AVPR1A,BCL11A,BMP6,CASR,CBL,CD40,CLEC16A,CYBB,DAPL1,DEPDC5,DSC2,HIGD1A,INHBB,ITGA6,JUN,P2RX7,P2RY1,PIK3C2B,POSTN,PTGER4,RYR3,STK26,TLR5,TLR7,TMEM150C,TNFRSF8,XPR1 |
| GO_PEPTIDYL_SERINE_MODIFICATION | 6.6e-06 | 8.0e-05 | 1813 | 319 | 29 | CAMK4,DCLK1,DYRK1B,GALNT13,GALNT16,IL11,LMTK2,MAP4K1,MARK1,MAST1,MKNK1,NCK2,NDNF,NOS1,OPRD1,PLCL2,PRKCG,PRKCZ,PRKD2,RPS6KA3,SBK1,SGK2,SH2D3A,SH2D3C,SPOCK2,SPOCK3,TENM1,TSSK1B,VRK3 |
| GO_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | 6.6e-06 | 7.9e-05 | 1813 | 58 | 11 | C5,CD74,CLEC7A,CSF1R,FFAR2,HAVCR2,IL33,IL7,MBP,POSTN,TLR7 |
| GO_TELENCEPHALON_DEVELOPMENT | 6.7e-06 | 8.0e-05 | 1813 | 253 | 25 | ATOH1,AVPR1A,BMERB1,CDH2,CDK5R2,CSF1R,DRD2,EFNA2,EOMES,EPHB2,EPHB3,EXT1,GRIN1,KDM1A,LHX6,LRP6,NKX2-1,NRP2,PAX5,RARB,ROBO1,RTN4RL2,SCN5A,SEMA7A,TACC1 |
| GO_ENTRY_INTO_HOST | 6.9e-06 | 8.4e-05 | 1813 | 133 | 17 | CBL,CD209,CD74,CD86,CDH1,CDHR3,CR2,FCN1,GRB2,HTR2A,ITGB7,MRC1,NCAM1,NECTIN2,SELPLG,TMPRSS2,XPR1 |
| GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | 6.9e-06 | 8.4e-05 | 1813 | 147 | 18 | ABHD5,ABHD6,AGAP2,AVPR1A,BMP6,CD74,CNEP1R1,CPT1A,DISP3,FGF21,FGFR3,FPR2,HTR2A,PLIN5,PTK2,RDH10,RGN,SIRT4 |
| GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 7.0e-06 | 8.4e-05 | 1813 | 337 | 30 | ADHFE1,ASRGL1,AZIN2,CRYM,DDC,GAD1,GLDC,GLS,GLS2,HAL,HNF4A,HYKK,MAT1A,MTAP,NOS1,NOS2,NOX4,NOXRED1,OAT,OAZ2,PADI4,PSMD9,RIMKLA,RIMKLB,SDS,SIRT4,TARS3,TAT,TPH1,TPH2 |
| GO_NATURAL_KILLER_CELL_MEDIATED_IMMUNE_RESPONSE_TO_TUMOR_CELL | 7.0e-06 | 8.4e-05 | 1813 | 9 | 5 | CEACAM1,CRTAM,HAVCR2,IL12A,NECTIN2 |
| GO_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | 7.1e-06 | 8.5e-05 | 1813 | 254 | 25 | ABCA5,ABCG4,ANXA9,ASIC3,BMP6,CEACAM1,CHRNB2,CLU,DRD2,DRD4,HTR2A,LRP6,MAPK15,NOS1,P2RY1,RAB3B,SERAC1,SLC18A2,SLC6A4,SLCO2B1,STX12,STX1A,SYT13,SYT2,SYT5 |
| GO_CELL_FATE_COMMITMENT | 7.5e-06 | 8.9e-05 | 1813 | 271 | 26 | APC2,ATOH1,CYP26B1,DHH,DLL4,EBF2,EOMES,FGFR1,FGFR2,FOXA1,GCM1,HEY2,IL23R,IL7,LY9,MNX1,MYL2,NKX2-1,NKX6-1,NOTCH3,POU4F1,SOSTDC1,SOX6,SPDEF,SPN,ZNF521 |
| GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 7.5e-06 | 8.9e-05 | 1813 | 94 | 14 | AFAP1L2,CBL,CEACAM1,GRB2,HAP1,LGMN,NCK2,NEURL1,PTPN3,SH3TC2,SHKBP1,SOCS4,STAM2,ZGPAT |
| GO_TRANSMISSION_OF_NERVE_IMPULSE | 7.5e-06 | 9.0e-05 | 1813 | 70 | 12 | AVPR1A,CACNA1G,CACNA1I,CHRNB4,FKBP1B,JAM3,KCND2,MYH14,NFASC,OTOA,SCN3A,SCN5A |
| GO_NEURAL_PRECURSOR_CELL_PROLIFERATION | 7.6e-06 | 9.1e-05 | 1813 | 148 | 18 | CDH2,CEND1,CX3CR1,DISP3,DLL4,DRD2,EML1,FGFR1,FGFR2,FZD9,GLI1,GPR37L1,IFT20,KDM1A,NES,PTPRZ1,SLC6A4,SPINT1 |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 7.8e-06 | 9.3e-05 | 1813 | 463 | 37 | ACSL6,ACSM2A,ACSM3,ADA2,ADCY4,AK5,AK9,CARD11,ELOVL4,ESRRB,GPAT4,GUCA1B,GUCA1C,GUCY1A1,GUCY1A2,GUCY1B1,HTR2A,KDM1A,LRGUK,MFN1,MPP1,MTAP,NOS1,NOS2,OGDHL,P2RX7,PANK3,PDE10A,PDE4C,PRTFDC1,SAMHD1,SLC22A11,SULT2B1,SULT4A1,THEM4,TIGAR,TPST1 |
| GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | 7.9e-06 | 9.4e-05 | 1813 | 322 | 29 | BTRC,CARD11,CD209,CLEC7A,FCN1,FFAR2,FGG,HAVCR2,HCK,ICAM2,ITGAM,LGMN,LILRA2,LTF,MAP2K6,MUC20,PELI1,PIK3AP1,PSMD9,RNF125,RPS6KA3,S100A9,SCIMP,SFTPA2,SMPDL3B,TLR10,TLR5,TLR7,UBE2D1 |
| GO_TISSUE_HOMEOSTASIS | 8.2e-06 | 9.7e-05 | 1813 | 224 | 23 | AZGP1,CD34,CD38,CDH3,CNGB1,CORO1A,CRACD,CSF1R,ESRRB,IAPP,IL7,ILDR2,LTF,NOX4,P2RX7,PIGR,POTEE,POTEF,POTEI,RDH12,TUB,USH2A,VSIG1 |
| GO_RENAL_SYSTEM_PROCESS | 8.3e-06 | 9.8e-05 | 1813 | 121 | 16 | ADCY4,ADRA1A,AVPR1A,CD34,CHRNB2,CHRNB4,CORIN,CYP4F12,DRD2,EMP2,HSD11B2,LGMN,PCSK5,PRKAR2B,SLC4A5,SULF2 |
| GO_PRIMARY_AMINO_COMPOUND_BIOSYNTHETIC_PROCESS | 8.4e-06 | 9.9e-05 | 1813 | 5 | 4 | AZIN2,DDC,TPH1,TPH2 |
| GO_BONE_MATURATION | 8.6e-06 | 1.0e-04 | 1813 | 22 | 7 | FGFR3,GREM1,LTF,PHOSPHO1,RYR1,SEMA4D,XYLT1 |
| GO_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 8.6e-06 | 1.0e-04 | 1813 | 108 | 15 | ACTN2,ADRA1A,CASR,CX3CR1,CXCR2,DRD2,FPR2,GPR4,GPR65,HTR2A,NMUR1,OPRD1,OPRK1,P2RY1,P2RY8 |
| GO_MEMBRANE_FUSION | 9.2e-06 | 1.1e-04 | 1813 | 150 | 18 | ANXA9,CALR,CORO1A,CPLX1,DOC2B,GCA,GRIK5,IZUMO1,MFN1,NAPG,NECTIN2,NOX5,SEC22B,STX11,STX12,STX1A,STX6,TRIM9 |
| GO_O_GLYCAN_PROCESSING | 9.2e-06 | 1.1e-04 | 1813 | 60 | 11 | B3GNT3,B4GALT5,CHST4,GALNT10,GALNT13,GALNT6,GALNT9,GCNT3,GCNT4,MUC20,ST3GAL2 |
| GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 9.2e-06 | 1.1e-04 | 1813 | 150 | 18 | BTN2A2,CBL,CEACAM1,FGFR1,HTR2A,JAK2,NKX3-1,NYAP2,PIK3AP1,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PPP1R16B,PREX2,PTK2,SEMA4D,UNC5B |
| GO_ACTIVATION_OF_GTPASE_ACTIVITY | 9.6e-06 | 1.1e-04 | 1813 | 96 | 14 | APC2,ARHGEF10,EVI5,GPR65,GRTP1,RALGAPB,RASGRF1,SCRIB,SGSM1,SGSM3,TBC1D1,TBC1D29P,TBC1D30,USP6NL |
| GO_HINDBRAIN_DEVELOPMENT | 1.0e-05 | 1.2e-04 | 1813 | 151 | 18 | AHI1,CDK5R2,CEND1,CNTN1,EGR2,GLI1,GPR37L1,GRIN1,HAP1,KCNC1,KNDC1,LRP6,MYO16,POU4F1,SCN5A,SCRIB,SLC6A4,SSTR2 |
| GO_MESENCHYME_DEVELOPMENT | 1.0e-05 | 1.2e-04 | 1813 | 276 | 26 | ACVRL1,DACT3,EOMES,EPB41L5,FGFR1,FGFR2,FOXA1,GREM1,HEY2,HEYL,LDLRAD4,LRP6,MEOX1,MSX2,NKX2-1,NRP2,OLFM1,PITX2,RBM24,RDH10,ROBO1,SEMA4D,SEMA7A,SNAI1,TMEM100,ZNF703 |
| GO_NEGATIVE_REGULATION_OF_LOCOMOTION | 1.0e-05 | 1.2e-04 | 1813 | 396 | 33 | ABHD6,ACVR1C,ACVRL1,ARHGAP4,BMERB1,C5,CALR,CCN3,CD74,CDH1,CHRD,CX3CR1,DLL4,DPYSL3,DRD2,DUSP1,GREM1,IL33,LDLRAD4,MAGI2,MAPK15,MIA3,NKX2-1,PTGER4,RGN,ROBO1,SEMA4D,SEMA7A,SPOCK3,SRGAP3,STK26,TMEFF2,WAS |
| GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 1.0e-05 | 1.2e-04 | 1813 | 227 | 23 | ACVR1C,AICDA,ANXA9,CALR,CEACAM1,DRD2,FCN1,HAVCR2,JUN,LILRA2,LTF,OAS1,OASL,PAEP,POU2F3,RNF125,SAMHD1,SCRIB,SERPINB9,SIGLEC11,SPINK13,SRPK2,TRAFD1 |
| GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 1.0e-05 | 1.2e-04 | 1813 | 259 | 25 | C5,CD40,CD74,CHRNA7,DRD4,DUSP9,FGD2,FGF18,FGFR1,GHR,HTR2A,JAK2,KSR1,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MUC20,NOX4,P2RX7,PIK3R5,ROBO1,TENM1 |
| GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | 1.0e-05 | 1.2e-04 | 1813 | 414 | 34 | ABHD5,ABHD6,AGAP2,ALAS1,AVPR1A,BMP6,CD74,CEACAM1,CNEP1R1,CPT1A,CYP1A1,DHH,DISP3,ENHO,ETFBKMT,FGF21,FGFR3,FGFR4,FPR2,GRHL1,HNF4A,HTR2A,LSR,MALRD1,ORMDL3,PIK3R5,PLIN5,PTK2,RDH10,RGN,SIRT4,SLA2,SNAI1,SOCS4 |
| GO_ACTIVATION_OF_PHOSPHOLIPASE_C_ACTIVITY | 1.1e-05 | 1.3e-04 | 1813 | 31 | 8 | ADCYAP1R1,ADRA1A,ARHGAP6,AVPR1A,HTR2A,ITK,NMUR1,TXK |
| GO_CELLULAR_AMINO_ACID_CATABOLIC_PROCESS | 1.1e-05 | 1.3e-04 | 1813 | 124 | 16 | ADHFE1,ASRGL1,CRYM,GAD1,GLDC,GLS,GLS2,HAL,HYKK,MAT1A,NOS1,NOS2,OAT,PADI4,SDS,TAT |
| GO_CELLULAR_RESPONSE_TO_XENOBIOTIC_STIMULUS | 1.1e-05 | 1.3e-04 | 1813 | 182 | 20 | AHR,AKR7A3,AKR7L,AOC1,CES3,CYP1A1,CYP1A2,CYP26B1,CYP2B6,CYP2J2,CYP2S1,CYP46A1,GHR,GRIN1,GSTM3,HNF4A,LPO,NAT2,RYR1,RYR3 |
| GO_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 1.1e-05 | 1.2e-04 | 1813 | 433 | 35 | BTRC,CAMK1D,CARD11,CD40,CDKN2A,CLU,CX3CR1,EDA,EOMES,FOXA1,GREM1,HAVCR2,HCK,HEYL,JAK2,JUN,KDM1A,LPAR5,LRP6,LTF,MAPK10,MAPK11,MSX2,NEUROG2,NKX3-1,NKX6-1,OPRD1,PELI1,POU4F1,PRKCZ,PRKD2,PTGIS,S100A9,STK3,ZNF431 |
| GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH | 1.1e-05 | 1.2e-04 | 1813 | 110 | 15 | ARHGAP4,CDKL3,DCC,DRAXIN,ISLR2,IST1,NKX6-1,NTN1,OLFM1,RND2,SEMA4D,SEMA7A,SHTN1,TRPV2,ZFYVE27 |
| GO_RESPONSE_TO_ACID_CHEMICAL | 1.1e-05 | 1.3e-04 | 1813 | 345 | 30 | ACER2,AMIGO1,AVPR1A,BCL11A,BMP6,BRINP1,BRINP2,CD38,CPEB3,CPT1A,CYBB,CYP26B1,DUSP1,FFAR2,FGF21,FGFR2,GLDC,GLRA3,GRIN1,IGFBP2,KCNMB1,MAPK10,NEURL1,NFATC4,PTAFR,PTGER4,RARB,RORB,SLC6A4,TESC |
| GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | 1.1e-05 | 1.3e-04 | 1813 | 152 | 18 | AHR,AKAP6,DUSP1,HCN2,HCN4,JUN,KCNJ11,KDM1A,NOX4,P2RX7,P2RY1,PTAFR,RYR1,RYR3,SELL,SLC5A5,SLC6A1,SLC6A4 |
| GO_SYNAPTIC_TRANSMISSION_CHOLINERGIC | 1.1e-05 | 1.3e-04 | 1813 | 31 | 8 | ACHE,ANXA9,CHRFAM7A,CHRNA10,CHRNA7,CHRNB2,CHRNB4,RIC3 |
| GO_CYTOSOLIC_CALCIUM_ION_TRANSPORT | 1.2e-05 | 1.4e-04 | 1813 | 183 | 20 | ADCYAP1R1,ADRA1A,AKAP6,CACNA2D1,CORO1A,DRD2,FAM155A,FKBP1B,GRIN1,HAP1,HTR2A,NOS1,P2RX7,PLCD1,PLCH1,PLCL2,RGS9,RYR1,RYR3,TRPA1 |
| GO_NEGATIVE_REGULATION_OF_DEPHOSPHORYLATION | 1.2e-05 | 1.4e-04 | 1813 | 111 | 15 | CAMSAP3,ELFN1,FKBP1B,GPATCH2,LMTK2,LMTK3,NCKAP1L,PPP1R14C,PPP1R16B,PPP1R1C,RGN,RIMBP2,SEMA4D,SFI1,SH3RF2 |
| GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 1.2e-05 | 1.3e-04 | 1813 | 73 | 12 | ACTN2,AKAP6,AMIGO1,CACNA2D1,CACNB2,EPHB2,FGF14,HAP1,KCNC1,KCNJ11,NOS1AP,RGS9 |
| GO_REGULATION_OF_CARDIAC_CONDUCTION | 1.2e-05 | 1.3e-04 | 1813 | 73 | 12 | ATP1A3,ATP1B1,ATP1B2,ATP2A3,ATP2B2,CORIN,FKBP1B,FXYD7,KCNJ11,NOS1,RYR1,RYR3 |
| GO_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION | 1.3e-05 | 1.5e-04 | 1813 | 41 | 9 | ATP1B1,CACNA2D1,KCNE5,KCNH2,KCNJ5,KCNN2,NOS1AP,SCN4B,SCN5A |
| GO_DOPAMINE_TRANSPORT | 1.3e-05 | 1.4e-04 | 1813 | 51 | 10 | CHRNB2,DRD2,DRD4,HTR2A,MAPK15,RAB3B,SLC18A2,SYT13,SYT2,SYT5 |
| GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 1.3e-05 | 1.5e-04 | 1813 | 199 | 21 | BCL11A,BTRC,CASR,COL19A1,DLL4,DRD2,FGFR1,FGFR2,FOXA1,GCM1,GRB2,GREB1L,GREM1,HOXB13,LRP6,MSX2,NFATC4,NKX2-1,NKX3-1,RDH10,SPINT1 |
| GO_NEURAL_NUCLEUS_DEVELOPMENT | 1.3e-05 | 1.4e-04 | 1813 | 62 | 11 | CDK5R2,CHRNB2,DYNLL1,KCNC1,MBP,NDRG2,NKX2-1,PLP1,POTEE,SCRIB,SYPL2 |
| GO_REGULATION_OF_PROTEIN_DEPHOSPHORYLATION | 1.3e-05 | 1.4e-04 | 1813 | 139 | 17 | CNEP1R1,DRD2,DUSP26,ELFN1,FKBP1B,JAK2,LMTK2,MAGI2,NCKAP1L,PPP1R14C,PPP1R16B,PPP1R1C,PPP2R2C,RGN,SH3RF2,SYMPK,VRK3 |
| GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT | 1.3e-05 | 1.4e-04 | 1813 | 62 | 11 | ATP1B1,ATP1B2,DRD4,FXYD7,NEDD4L,NOS1,PTPN3,SCN3B,SCN4B,SCN5A,TESC |
| GO_STEROID_METABOLIC_PROCESS | 1.3e-05 | 1.5e-04 | 1813 | 331 | 29 | AKR1B15,AKR1D1,BMP6,CEBPA,CYB5R1,CYP1A1,CYP1A2,CYP26B1,CYP27A1,CYP2B6,CYP39A1,CYP46A1,DHH,DHRS2,DHRS9,DISP3,FGFR1,FGFR4,HSD11B2,HSD17B6,LGMN,MALRD1,NR5A2,OSBPL6,SNAI1,SRD5A2,SULT2B1,SULT4A1,TFCP2L1 |
| GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | 1.3e-05 | 1.5e-04 | 1813 | 112 | 15 | ALOX15,AVPR1A,CD74,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F3,CYP4F8,ELOVL4,PLA2G4A,PTGIS,PTGR1 |
| GO_DIENCEPHALON_DEVELOPMENT | 1.4e-05 | 1.5e-04 | 1813 | 74 | 12 | CDH1,CHRNB2,DRD2,GLI1,HAP1,HESX1,KCNC1,LRP6,NKX2-1,NRP2,PITX2,POU4F1 |
| GO_MAMMARY_GLAND_DUCT_MORPHOGENESIS | 1.4e-05 | 1.6e-04 | 1813 | 32 | 8 | BTRC,CSF1R,FGFR2,LRP6,MSX2,NTN1,SCRIB,SOSTDC1 |
| GO_MESENCHYMAL_CELL_DIFFERENTIATION | 1.4e-05 | 1.6e-04 | 1813 | 216 | 22 | DACT3,EOMES,EPB41L5,FGFR1,FGFR2,FOXA1,GREM1,HEY2,HEYL,LDLRAD4,LRP6,MSX2,NKX2-1,NRP2,OLFM1,PITX2,RDH10,SEMA4D,SEMA7A,SNAI1,TMEM100,ZNF703 |
| GO_RETINA_HOMEOSTASIS | 1.4e-05 | 1.5e-04 | 1813 | 74 | 12 | AZGP1,CDH3,CNGB1,ESRRB,LTF,PIGR,POTEE,POTEF,POTEI,RDH12,TUB,USH2A |
| GO_EXPORT_ACROSS_PLASMA_MEMBRANE | 1.5e-05 | 1.7e-04 | 1813 | 52 | 10 | ABCB1,ABCC1,ATP1A3,ATP1B1,ATP1B2,KCNE5,KCNH2,KCNT2,RGS9,SLC40A1 |
| GO_PLACENTA_DEVELOPMENT | 1.5e-05 | 1.6e-04 | 1813 | 155 | 18 | CEBPA,EOMES,FGFR2,GCM1,GRB2,HEY2,HS6ST1,LHX4,MC2R,PCDH12,PLAC1,PLCD1,PTGIS,PTK2,SNAI1,SPINT1,STK3,VASH2 |
| GO_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION | 1.5e-05 | 1.7e-04 | 1813 | 52 | 10 | ABCB1,ABCC1,ANO3,ANO9,ATP8A2,P2RX7,SLC66A2,TMEM30A,XKR4,XKR5 |
| GO_SMOOTHENED_SIGNALING_PATHWAY | 1.5e-05 | 1.7e-04 | 1813 | 141 | 17 | ARL6,BOC,BTRC,DCDC2,DHH,DISP1,DISP3,FGFR2,FOXA1,GLI1,GPC2,GPR37L1,IFT20,IFT80,IQUB,NKX6-1,SCUBE1 |
| GO_MEMBRANE_BIOGENESIS | 1.6e-05 | 1.8e-04 | 1813 | 42 | 9 | ANXA9,CDH2,EMP2,EPHB2,IL1RAPL1,MAGI2,NRXN1,NRXN2,UGCG |
| GO_RESPONSE_TO_AMMONIUM_ION | 1.6e-05 | 1.8e-04 | 1813 | 186 | 20 | AOC1,CHRM4,CHRNA7,CHRNB2,DRD2,DRD4,GABRA1,GABRB2,GLDC,GNAL,GNAO1,GRIN1,HTR2A,HTR3A,HTR3B,PRKCG,PTAFR,RGS10,RGS9,SLC6A1 |
| GO_ALPHA_BETA_T_CELL_DIFFERENTIATION | 1.7e-05 | 1.9e-04 | 1813 | 101 | 14 | CD83,CD86,EOMES,HLX,IL23R,ITK,LY9,NCKAP1L,PLA2G2D,PRKCZ,PTGER4,RUNX3,SPN,TCF7 |
| GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | 1.7e-05 | 1.8e-04 | 1813 | 114 | 15 | B3GNT3,B4GALT4,B4GALT5,CHST4,CHST6,CSGALNACT1,CSPG5,EXT1,FMOD,GPC2,HS6ST1,PRELP,ST3GAL2,VCAN,XYLT1 |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 1.7e-05 | 1.9e-04 | 1813 | 406 | 33 | AP3B2,ARL6,BICDL1,BICDL2,CBL,CDH3,CEP19,CEP83,CLMN,CNIH2,F5,GEM,GPR143,HAP1,KIF13A,KIF5A,KIF5C,MAP1S,MAPK15,MARK1,NECTIN2,NTN1,PPP6C,PRKCZ,PTK2,RAB17,RAD21L1,SCFD1,SCRIB,SEC22B,SLC2A4,SLIT1,SYBU |
| GO_MAMMARY_GLAND_DEVELOPMENT | 1.7e-05 | 1.8e-04 | 1813 | 142 | 17 | BCL2L11,BTRC,CSF1R,FGFR2,GPAT4,JAK2,KALRN,LRP6,MSX2,NEURL1,NTN1,ROBO1,SCRIB,SLC29A1,SOSTDC1,TPH1,ZNF703 |
| GO_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | 1.7e-05 | 1.9e-04 | 1813 | 157 | 18 | ATP1A3,ATP1B1,ATP1B2,ATP6V0B,ATP6V1C2,AVPR1A,CORIN,CXorf21,CYP4F12,DRD2,KCNH2,NEDD4L,SLC12A8,SLC4A10,SLC4A5,SLC4A8,SLC9B1,TMPRSS3 |
| GO_ARACHIDONIC_ACID_METABOLIC_PROCESS | 1.8e-05 | 2.0e-04 | 1813 | 53 | 10 | ALOX15,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F3,PLA2G4A,PTGIS |
| GO_CELL_CYCLE | 1.8e-05 | 2.0e-04 | 1813 | 1864 | 103 | ABCB1,AFAP1L2,AHR,AICDA,ANKK1,ARHGEF10,BCL2L11,BRINP1,BRINP2,BTN2A2,BTRC,CALR,CDC14A,CDK5R2,CDK9,CDKL3,CDKN2A,CEBPA,CNEP1R1,CNTD2,CYP1A1,CYP26B1,DCDC1,DIRAS3,DMRT1,DRD2,DUSP1,DYNLL1,EML1,EML4,ESRRB,EVI5,FAM9A,FAM9B,FBXL7,FBXO31,FGFR1,FGFR2,FOXA1,FSD1,FZD9,GEM,GLI1,HERC5,IL12A,IST1,JUN,KIAA1614,KIF13A,KLK10,LCMT1,LGMN,LRP6,LZTS1,MAGI2,MAP2K6,MAPK15,MAPRE3,MLF1,MSX2,MYO16,NABP1,NES,NKX3-1,NOX5,NUGGC,PARD6G,PHC1,PIWIL3,POU4F1,PPP1R1C,PPP2R2C,PPP6C,PRKAR2B,PSMD9,PTPN3,RAB11FIP4,RAD21L1,RB1CC1,RBM38,RPS6KA3,RUNX3,SCRIB,SEPTIN3,SEPTIN4,SEPTIN6,SFI1,SGSM3,SLC6A4,SOX4,SRPK2,SYCE2,TACC1,TAF1L,TDRKH,TEX11,TEX12,TUBB2A,TUBB4A,UBA3,UBE2D1,ZNF703,ZNRD2 |
| GO_CELLULAR_DEFENSE_RESPONSE | 1.8e-05 | 2.0e-04 | 1813 | 53 | 10 | CCR6,CD300C,CX3CR1,CXCR2,DCDC2,GNLY,ITK,KLRC3,SH2D1A,SPN |
| GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 1.8e-05 | 2.0e-04 | 1813 | 481 | 37 | ALOX15,BTN2A2,C5,CCN3,CD22,CD74,CD86,CEACAM1,CST7,CXCR2,DRD2,DUSP1,FGL1,GREM1,HAVCR2,HLX,IL33,LILRA2,LRFN5,LTF,MIA3,PELI1,PLA2G2D,PLCL2,PTGER4,RNF125,RUNX3,SAMHD1,SCRIB,SERPINB9,SLA2,SMPDL3B,SPN,TAFA3,TMEM176B,TRAFD1,ZBTB46 |
| GO_RESPONSE_TO_AMPHETAMINE | 1.8e-05 | 2.0e-04 | 1813 | 33 | 8 | ASIC1,DRD2,DRD4,GRIN1,PDE1B,RGS10,RGS9,SLC18A2 |
| GO_EMBRYONIC_PLACENTA_DEVELOPMENT | 1.9e-05 | 2.1e-04 | 1813 | 89 | 13 | CEBPA,EOMES,FGFR2,GCM1,GRB2,HEY2,HS6ST1,PCDH12,PLCD1,SNAI1,SPINT1,STK3,VASH2 |
| GO_PROTEOGLYCAN_METABOLIC_PROCESS | 1.9e-05 | 2.1e-04 | 1813 | 89 | 13 | B3GAT2,CSGALNACT1,CSPG5,EXT1,EXTL2,HS6ST1,HYAL4,NDNF,SPOCK2,SPOCK3,SULF2,VCAN,XYLT1 |
| GO_RECEPTOR_MEDIATED_ENDOCYTOSIS | 1.9e-05 | 2.1e-04 | 1813 | 320 | 28 | ACHE,AHI1,ANXA9,ASGR1,BMP2K,CALR,CBL,CEACAM1,CLU,CXCR2,DRD2,DRD4,FCHO1,FPR2,GRB2,GREM1,HBA1,HP,ITGAM,LRP6,MAGI2,MAPK8IP1,MAPK8IP2,MRC1,SCGB3A2,SCRIB,SCYL2,STAB1 |
| GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT | 1.9e-05 | 2.1e-04 | 1813 | 89 | 13 | ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,KCNC1,KCNE5,KCNH2,KCNIP4,KCNMB1,KCNN2,NEDD4L,NOS1AP |
| GO_ADHERENS_JUNCTION_ORGANIZATION | 2.0e-05 | 2.2e-04 | 1813 | 65 | 11 | BMP6,CADM2,CAMSAP3,CDH1,CDH15,CDH2,CDH3,CDHR3,JAM3,NECTIN2,ZNF703 |
| GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 2.0e-05 | 2.1e-04 | 1813 | 338 | 29 | C5,CD40,CD74,CHRNA7,DRD4,DUSP1,DUSP9,EPHB2,FGD2,FGF18,FGFR1,GHR,HTR2A,JAK2,KSR1,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MAPK8IP1,MUC20,NOX4,P2RX7,PIK3R5,ROBO1,SH2B3,TENM1 |
| GO_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | 2.0e-05 | 2.1e-04 | 1813 | 43 | 9 | CEACAM1,CRTAM,HAVCR2,IL12A,NECTIN2,RAET1G,SERPINB9,SH2D1A,VAV1 |
| GO_SEX_DIFFERENTIATION | 2.0e-05 | 2.2e-04 | 1813 | 270 | 25 | ACVR2A,ADCYAP1R1,BCL2L11,BIK,BMP6,CBL,DHH,DMRT1,GDF9,GREB1L,HNF4A,INHBB,IRX5,LRP6,NKX2-1,NKX3-1,NUP210L,PCYT1B,RAD21L1,RDH10,SLIT3,SRD5A2,TCF7,TEX11,TNFSF10 |
| GO_CELLULAR_HORMONE_METABOLIC_PROCESS | 2.1e-05 | 2.2e-04 | 1813 | 130 | 16 | ADH1B,AKR1B15,AKR1D1,BMP6,CYP1A1,CYP1A2,CYP26B1,CYP2S1,CYP46A1,DHRS2,DHRS9,HSD17B6,RBP1,RDH10,RDH12,SRD5A2 |
| GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | 2.1e-05 | 2.2e-04 | 1813 | 130 | 16 | AKIRIN1,CALR,CAMK1D,CCR6,CD74,CX3CR1,CXCR2,DAPK2,DOCK8,FPR2,IL12A,LGMN,MIA3,NCKAP1L,PTAFR,SPN |
| GO_ORGANIC_ACID_CATABOLIC_PROCESS | 2.2e-05 | 2.3e-04 | 1813 | 271 | 25 | ADHFE1,AKR1D1,ASRGL1,CPT1A,CPT1C,CRYM,CYP26B1,CYP39A1,CYP4F12,CYP4F3,ETFBKMT,GAD1,GLDC,GLS,GLS2,HAL,HYKK,MAT1A,NOS1,NOS2,OAT,PADI4,PLIN5,SDS,TAT |
| GO_KERATAN_SULFATE_METABOLIC_PROCESS | 2.3e-05 | 2.5e-04 | 1813 | 34 | 8 | B3GNT3,B4GALT4,B4GALT5,CHST4,CHST6,FMOD,PRELP,ST3GAL2 |
| GO_POSITIVE_REGULATION_OF_AMINE_TRANSPORT | 2.3e-05 | 2.5e-04 | 1813 | 34 | 8 | AVPR1A,CHRNB2,DRD2,DRD4,P2RX7,RAB3B,SLC6A1,STX1A |
| GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 2.4e-05 | 2.6e-04 | 1813 | 44 | 9 | ACVR1C,ACVR2A,ACVRL1,DMRT1,GDF6,IGSF1,INHBB,MAGI2,TDGF1P3 |
| GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS | 2.4e-05 | 2.6e-04 | 1813 | 44 | 9 | B3GAT2,CSGALNACT1,CSPG5,HYAL4,NDNF,SPOCK2,SPOCK3,VCAN,XYLT1 |
| GO_CIRCADIAN_RHYTHM | 2.4e-05 | 2.5e-04 | 1813 | 207 | 21 | AHR,BTRC,CHRNB2,CPT1A,DDC,DRD2,DRD4,HNF4A,HUWE1,JUN,KCND2,MAPK10,NGFR,NKX2-1,NOS2,PRKCG,RORB,SLC6A4,SPSB4,TPH1,TPH2 |
| GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | 2.4e-05 | 2.6e-04 | 1813 | 104 | 14 | ADAM11,CEACAM1,EMP2,FYB2,HCK,ITGA6,ITGAL,ITGAM,ITGAX,ITGB7,PLP1,PTK2,SEMA7A,VAV1 |
| GO_PLASMA_MEMBRANE_ORGANIZATION | 2.4e-05 | 2.6e-04 | 1813 | 104 | 14 | ANO3,ANO9,CLU,CRB1,FA2H,MYRF,P2RX7,SH3TC2,SPTA1,SYPL2,TMEFF2,UGCG,XKR4,XKR5 |
| GO_RESPONSE_TO_HISTAMINE | 2.4e-05 | 2.6e-04 | 1813 | 11 | 5 | AOC1,DRD2,DRD4,GABRA1,GABRB2 |
| GO_RESPONSE_TO_PEPTIDE | 2.4e-05 | 2.6e-04 | 1813 | 525 | 39 | ABCC1,ACTN2,ACVR1C,ADCY4,ATP1A3,ATP6V0B,ATP6V1C2,BCL2L11,CACNA2D1,CASR,CD40,CEACAM1,CHRNA7,CYBB,EGR2,ENHO,FGF21,FPR2,GHR,GRB2,HSD11B2,INHBB,JAK2,KLF5,LGMN,LRP6,MMP13,NGFR,NKX6-1,PRKAR2B,PRKCZ,PTK2,SLC2A4,SLC30A10,STAT4,SYAP1,TIMP4,TNFSF10,VWA2 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 2.5e-05 | 2.7e-04 | 1813 | 802 | 53 | ACTN2,ADCYAP1R1,AKAP6,ANXA9,ARHGAP44,CABP1,CDH1,CDH2,CDH3,CHP2,CNIH2,CORO1A,CRIPT,DCLK1,DMAP1,DRD4,EPHB2,FKBP1B,FZD9,GPC2,GPR143,GRIN1,HAP1,HUWE1,ITGAM,KCNJ11,KDM1A,KIAA1614,LRRC15,MAGI2,MAPK15,MESD,MRLN,NEDD4L,NGFR,NOS1,OAZ2,P2RX7,PARD6G,PLS1,PRKCZ,RAB29,REEP1,SCFD1,SCRIB,SH3TC2,SIRT4,SLC2A4,STX6,SYBU,TENM1,TMEM30A,VSNL1 |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 2.5e-05 | 2.6e-04 | 1813 | 526 | 39 | ACVR1C,AMIGO1,AOC1,ASGR1,AVPR1A,BCL11A,BMP8A,CASR,CBL,CD40,CLEC16A,CYBB,CYP1A1,CYP26B1,DAPL1,DEPDC5,DSC2,FGF21,FKBP1B,GRIN1,HIGD1A,HSD11B2,IGFBP2,INHBB,ITGA6,JUN,KCNJ11,P2RX7,P2RY1,PIK3C2B,POSTN,PRKCG,RYR3,SELL,SLC6A4,SSTR2,STK26,TPH2,XPR1 |
| GO_CALCIUM_ION_TRANSMEMBRANE_IMPORT_INTO_CYTOSOL | 2.6e-05 | 2.8e-04 | 1813 | 147 | 17 | AKAP6,CACNA2D1,CORO1A,DRD2,FAM155A,FKBP1B,GRIN1,HAP1,HTR2A,NOS1,P2RX7,PLCD1,PLCH1,PLCL2,RYR1,RYR3,TRPA1 |
| GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | 2.6e-05 | 2.8e-04 | 1813 | 177 | 19 | AKIRIN1,ARHGAP44,DCDC2,DPYSL3,HAP1,IFT20,KCTD17,KLF5,MAPK15,MYO10,NEURL1,P2RX7,PODXL,PPP1R16B,RAB17,RAP1GAP,TBC1D30,TENM1,WAS |
| GO_ENDOTHELIUM_DEVELOPMENT | 2.8e-05 | 2.9e-04 | 1813 | 133 | 16 | ACVRL1,ANXA9,BMP6,CD34,CEACAM1,DLL4,GSTM3,HEY2,ITGAX,PPP1R16B,PRKD2,S1PR3,SCUBE1,SLC40A1,TJP1,TMEM100 |
| GO_ANIMAL_ORGAN_MATURATION | 2.9e-05 | 3.0e-04 | 1813 | 26 | 7 | FGFR3,GREM1,LTF,PHOSPHO1,RYR1,SEMA4D,XYLT1 |
| GO_GLYCOSPHINGOLIPID_BIOSYNTHETIC_PROCESS | 2.9e-05 | 3.0e-04 | 1813 | 26 | 7 | B4GALT5,FA2H,ST3GAL5,ST8SIA1,ST8SIA6,UGCG,UGT8 |
| GO_LEUKOCYTE_TETHERING_OR_ROLLING | 2.9e-05 | 3.0e-04 | 1813 | 26 | 7 | ADD2,CX3CR1,ITGB7,PTAFR,SELL,SELPLG,SPN |
| GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 2.9e-05 | 3.0e-04 | 1813 | 148 | 17 | ADD2,APC2,ARHGAP6,BMERB1,CAMSAP3,CORO1A,CRACD,IQCJ-SCHIP1,MAP6D1,PLEKHH2,SCIN,SPTA1,SPTAN1,SPTB,TMEFF2,TUBB4A,WAS |
| GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 2.9e-05 | 3.0e-04 | 1813 | 148 | 17 | BTN2A2,CD74,CD83,CD86,HLX,IL12A,IL23R,IL34,IL7,JUN,NCKAP1L,POU4F1,PRKCZ,RUNX3,TESC,TESPA1,ZBTB46 |
| GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 2.9e-05 | 3.0e-04 | 1813 | 26 | 7 | ACTN2,AKAP6,AMIGO1,ATP1B1,ATP1B2,KCNC1,NOS1AP |
| GO_REGULATION_OF_BINDING | 2.9e-05 | 3.0e-04 | 1813 | 381 | 31 | ACE,ADD2,ANXA9,CDK9,CFHR1,CRMP1,EBF2,EIF4A3,ENHO,EPB41L5,GREM2,HEY2,JAK2,JUN,KDM1A,MAPRE3,MRLN,MSX2,NES,NFATC4,NKX3-1,P2RY1,PLCL2,POU4F1,PRMT8,SLN,SPTA1,STK3,SYAP1,SYMPK,ZBTB7C |
| GO_REGULATION_OF_NMDA_RECEPTOR_ACTIVITY | 2.9e-05 | 3.0e-04 | 1813 | 35 | 8 | ACTN2,CNIH2,DAPK1,EPHB2,GRIN1,MAPK8IP2,RASGRF1,RGS9 |
| GO_RHYTHMIC_PROCESS | 2.9e-05 | 3.0e-04 | 1813 | 293 | 26 | AHR,BTRC,CHRNB2,CPT1A,DDC,DRD2,DRD4,EGR2,GDF9,HNF4A,HUWE1,JUN,KCND2,MAP2K6,MAPK10,NGFR,NKX2-1,NOS2,PRKCG,RORB,SLC6A4,SLIT3,SPSB4,TIMP4,TPH1,TPH2 |
| GO_SYNAPSE_MATURATION | 2.9e-05 | 3.0e-04 | 1813 | 26 | 7 | ADGRL1,CAMK2B,CX3CR1,NEURL1,NFATC4,NRXN1,SYBU |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 3.0e-05 | 3.1e-04 | 1813 | 134 | 16 | ADD2,CLU,CRACD,IAPP,JAM3,LCMT1,LDLRAD4,OPRD1,PRKCZ,PTGER4,SCIN,SPTA1,SPTAN1,SPTB,TRIM9,TUBB4A |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 3.0e-05 | 3.1e-04 | 1813 | 627 | 44 | ACSL6,ACSM2A,ACSM3,ADA2,ADCY4,AICDA,AK5,AK7,AK9,ASMTL,CARD11,CSGALNACT1,ELOVL4,ENTPD3,ESRRB,EXTL2,GPAT4,GUCA1B,GUCA1C,GUCY1A1,GUCY1A2,GUCY1B1,HTR2A,KDM1A,LRGUK,MFN1,MPP1,MTAP,NOS1,NOS2,OGDHL,P2RX7,PANK3,PDE10A,PDE4C,PRTFDC1,PTGIS,SAMHD1,SULT2B1,SULT4A1,TBPL1,THEM4,TIGAR,TPST1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 3.0e-05 | 3.1e-04 | 1813 | 56 | 10 | ACE,ADRA1A,AFAP1L2,CSF1R,DOK7,GPRC5B,GREM1,NEURL1,NOX4,SRCIN1 |
| GO_RECEPTOR_LOCALIZATION_TO_SYNAPSE | 3.0e-05 | 3.1e-04 | 1813 | 56 | 10 | ADAM22,ARHGAP44,CACNG7,CNIH2,CPLX1,KIF5A,KIF5C,MAPK10,PRKCZ,SCRIB |
| GO_RECEPTOR_METABOLIC_PROCESS | 3.1e-05 | 3.2e-04 | 1813 | 195 | 20 | ACHE,AHI1,ALS2,ANXA9,CEACAM1,CXCR2,DRD2,DRD4,FGF21,GRB2,GREM1,JAK2,LGMN,LMTK2,MAGI2,MYLIP,RAB29,RNF43,SCRIB,SCYL2 |
| GO_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 3.1e-05 | 3.2e-04 | 1813 | 149 | 17 | ACHE,ACVRL1,AHI1,ARL6,ATP8A2,CELF4,DLL4,GNAT2,IRX5,LRP6,RAB11FIP4,RORB,SDK2,SLC17A8,SLC4A5,TSPAN12,TUB |
| GO_CELL_RECOGNITION | 3.2e-05 | 3.3e-04 | 1813 | 211 | 21 | AMIGO1,CD209,CD6,CLEC7A,CRTAM,CSGALNACT1,DOCK8,EPHB2,EPHB3,FCN1,HAVCR2,HVCN1,IGSF9,IZUMO1,NCK2,OPCML,PAEP,PCDH12,ROBO1,TUB,VCAN |
| GO_NEGATIVE_REGULATION_OF_AXONOGENESIS | 3.2e-05 | 3.3e-04 | 1813 | 68 | 11 | ARHGAP4,CDKL3,DCC,DRAXIN,EPHB2,LINGO1,NGFR,NTN1,PTK2,SEMA4D,SEMA7A |
| GO_NEURAL_RETINA_DEVELOPMENT | 3.2e-05 | 3.3e-04 | 1813 | 68 | 11 | AHI1,ARL6,ATP8A2,DLL4,GNAT2,IRX5,RAB11FIP4,RORB,SDK2,SLC17A8,TSPAN12 |
| GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 3.3e-05 | 3.4e-04 | 1813 | 261 | 24 | ABHD5,ACHE,AGAP2,ALOX15,BMX,DDHD1,ETNPPL,FPR2,GPAT4,HTR2A,LIPH,LIPI,LPCAT2,PCYT1B,PHOSPHO1,PIK3C2B,PIK3R5,PIP4K2A,PIP5K1B,PLA2G2D,PLA2G4A,SBF1,SERAC1,SLC44A3 |
| GO_RESPONSE_TO_ORGANOPHOSPHORUS | 3.3e-05 | 3.4e-04 | 1813 | 135 | 16 | AHR,AKAP6,DUSP1,HCN2,HCN4,JUN,KCNJ11,KDM1A,NOX4,P2RX7,P2RY1,PTAFR,RYR3,SELL,SLC5A5,SLC6A4 |
| GO_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS | 3.4e-05 | 3.4e-04 | 1813 | 107 | 14 | ACSL6,ALOX15,CPT1A,CYP1A1,CYP1A2,CYP2B6,CYP2J2,CYP2S1,CYP4F12,CYP4F3,PLA2G4A,PLP1,PTGIS,SLC27A6 |
| GO_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 3.4e-05 | 3.5e-04 | 1813 | 150 | 17 | ACER2,ACVR1C,BCL2L11,CASP14,CLEC7A,COL4A3,CYFIP2,DAPK1,GRIN1,JAK2,LGMN,NGFR,NKX3-1,ROBO1,S100A9,TNFSF10,TNFSF15 |
| GO_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 3.4e-05 | 3.5e-04 | 1813 | 150 | 17 | FGG,HAVCR2,ITGAM,LGMN,LILRA2,LTF,PELI1,PIK3AP1,RPS6KA3,S100A9,SCIMP,SFTPA2,SMPDL3B,TLR10,TLR5,TLR7,UBE2D1 |
| GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | 3.5e-05 | 3.5e-04 | 1813 | 46 | 9 | ADGRL1,AMIGO1,CD209,CD6,CDH2,CRB1,IL1RAPL1,ITGAL,TENM1 |
| GO_CELLULAR_RESPONSE_TO_AMMONIUM_ION | 3.6e-05 | 3.7e-04 | 1813 | 136 | 16 | AOC1,CHRM4,CHRNA7,CHRNB2,DRD2,DRD4,GABRA1,GABRB2,GNAL,GNAO1,HTR2A,HTR3A,HTR3B,PTAFR,RGS10,RGS9 |
| GO_EPITHELIAL_CELL_PROLIFERATION | 3.7e-05 | 3.8e-04 | 1813 | 441 | 34 | ACVR2A,ACVRL1,BMP6,BTRC,CCL26,CCN3,CD34,CDH3,CEACAM1,DLL4,EAF2,FGFR1,FGFR2,FGL1,FLT4,GLI1,IFT80,JUN,LGR5,NGFR,NKX3-1,NKX6-1,NOX5,NRP2,PPP1R16B,PRKD2,RGN,ROBO1,RUNX3,SCG2,SCN5A,SULF2,VASH2,ZNF703 |
| GO_MODIFICATION_OF_MORPHOLOGY_OR_PHYSIOLOGY_OF_OTHER_ORGANISM | 3.7e-05 | 3.7e-04 | 1813 | 166 | 18 | ANXA9,BCL2L11,CD209,CLEC7A,CSF1R,GNLY,HTN3,JUN,KPNA1,KPNA5,KPNA7,LTF,NOS2,P2RX7,POU2F3,S100A9,SCRIB,SERPINB9 |
| GO_PROTEIN_CATABOLIC_PROCESS | 3.7e-05 | 3.8e-04 | 1813 | 938 | 59 | AGAP2,AMN1,ANXA9,APC2,AZIN2,BACE2,BTRC,CBL,CDH1,CEACAM1,CEBPA,CLEC16A,CLU,CPVL,DNAJC18,FBXL7,FBXO31,FBXO44,HUWE1,IL33,KCTD17,KCTD2,LAMP3,LGMN,MYLIP,NCCRP1,NEDD4L,NKD1,NOS2,OAZ2,OGA,P2RX7,PELI1,PRKCG,PSMD9,PTK2,PTPN3,RGN,RNF125,RNF216,RNF43,SEC22B,SGSM3,SGTB,SH3RF2,SOCS4,SPSB4,STT3B,TIMP3,TIMP4,TNFAIP1,TRIM9,UBAP1,UBE2D1,UBE2W,UBE3D,UBE4A,USP35,USP43 |
| GO_B_CELL_PROLIFERATION | 3.9e-05 | 4.0e-04 | 1813 | 95 | 13 | AHR,CARD11,CD22,CD38,CD40,CD70,CD74,CHRNB2,CR2,IL7,NCKAP1L,PELI1,PLCL2 |
| GO_ALPHA_BETA_T_CELL_ACTIVATION | 4.0e-05 | 4.0e-04 | 1813 | 137 | 16 | CD83,CD86,EOMES,HLX,IL12A,IL23R,ITK,LY9,MAPK8IP1,NCKAP1L,PLA2G2D,PRKCZ,PTGER4,RUNX3,SPN,TCF7 |
| GO_POSTSYNAPTIC_MEMBRANE_ASSEMBLY | 4.0e-05 | 4.0e-04 | 1813 | 12 | 5 | CDH2,EPHB2,MAGI2,NRXN1,NRXN2 |
| GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 4.1e-05 | 4.1e-04 | 1813 | 334 | 28 | ADCY4,C5,CD74,CHRNA7,DRD2,DRD4,DUSP9,EMP2,GHR,GPRC5B,GREM1,IL23R,JAK2,KSR1,MAP2K3,MAP2K6,MAP3K15,MAP4K1,MAPK10,MAPK11,MUC20,NCKAP1L,P2RX7,PRKAR2B,PRKCZ,STK26,STK3,TNFSF15 |
| GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | 4.1e-05 | 4.1e-04 | 1813 | 231 | 22 | ACTN2,ADRA1A,AKAP6,CALR,DLL4,FGFR1,FGFR2,GLI1,GREM1,HEY2,IFT20,KCNK2,MAPK11,MYL2,MYO18B,NOX4,POU4F1,RARB,SGCZ,SOX6,TNNI3,TNNT2 |
| GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT | 4.1e-05 | 4.1e-04 | 1813 | 58 | 10 | BMP6,FGFR1,GPAT4,HNF4A,KLF5,NKX6-1,RARB,SCRIB,SPDEF,TIGAR |
| GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 4.1e-05 | 4.2e-04 | 1813 | 183 | 19 | AMER2,ANKRD6,APC2,BICC1,CDH2,DACT3,DRAXIN,GLI1,GREM1,IGFBP2,LRP6,MAPK8IP1,MAPK8IP2,NKD1,PSMD9,SCYL2,SOSTDC1,STK3,TLE3 |
| GO_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | 4.1e-05 | 4.1e-04 | 1813 | 19 | 6 | CACNA1G,CACNA1I,CDK5R2,DOC2B,SCAMP5,STX1A |
| GO_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT | 4.2e-05 | 4.2e-04 | 1813 | 70 | 11 | BTRC,CSF1R,FGFR2,JAK2,LRP6,MSX2,NTN1,ROBO1,SCRIB,SOSTDC1,ZNF703 |
| GO_MACROPHAGE_ACTIVATION | 4.4e-05 | 4.4e-04 | 1813 | 96 | 13 | CD74,CEBPA,CLU,CST7,FPR2,HAVCR2,IL33,ITGAM,JAK2,JUN,LRFN5,TAFA3,TLR7 |
| GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 4.4e-05 | 4.4e-04 | 1813 | 96 | 13 | ARHGAP4,CDKL3,DCC,DRAXIN,EPHB2,LINGO1,NFATC4,NGFR,NTN1,POSTN,PTK2,SEMA4D,SEMA7A |
| GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | 4.4e-05 | 4.4e-04 | 1813 | 96 | 13 | ACTR3C,ALOX15,CCL26,CORO1A,CRACD,FCHSD1,GRB2,HCK,NCK2,NCKAP1L,SCIN,TENM1,WAS |
| GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 4.4e-05 | 4.4e-04 | 1813 | 96 | 13 | CADM4,CYBB,CYFIP2,ELMO2,FGF18,FLT4,MAPK11,NCK2,NCKAP1L,NRP2,PRKD2,PTK2,VAV1 |
| GO_CYTOKINE_METABOLIC_PROCESS | 4.5e-05 | 4.5e-04 | 1813 | 124 | 15 | CARD11,CD74,CD86,CLEC7A,CX3CR1,CYBB,INHBB,JAK2,MAP2K3,PCSK5,PTAFR,SPN,TLR7,TNFRSF8,TNFSF15 |
| GO_MICROTUBULE_BASED_TRANSPORT | 4.5e-05 | 4.4e-04 | 1813 | 184 | 19 | AP3B2,BICDL1,BICDL2,CAMSAP3,CFAP53,CNIH2,DYNLL1,HAP1,IFT20,IFT80,KIF13A,KIF27,KIF5A,KIF5C,KLC3,MAP1S,PRKCZ,SYBU,TUB |
| GO_NEGATIVE_REGULATION_OF_CELL_GROWTH | 4.5e-05 | 4.4e-04 | 1813 | 184 | 19 | ACVRL1,ARHGAP4,BCL11A,CCN3,CDKL3,CDKN2A,DACT3,DCC,DRAXIN,EAF2,GDF9,GNG4,GREM1,HNF4A,MYL2,NTN1,SEMA4D,SEMA7A,SLIT3 |
| GO_REGULATION_OF_OSSIFICATION | 4.5e-05 | 4.5e-04 | 1813 | 200 | 20 | ACVR2A,BMP2K,BMP6,CEBPA,CHRD,COMP,EGR2,FGFR2,FZD9,GLI1,GREM1,LTF,MSX2,P2RX7,PHOSPHO1,PTGER4,PTK2,RORB,SEMA4D,TPH1 |
| GO_GLIAL_CELL_ACTIVATION | 4.8e-05 | 4.7e-04 | 1813 | 59 | 10 | BACE2,CLU,CST7,FPR2,IL33,ITGAM,JAK2,JUN,TAFA3,TLR7 |
| GO_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | 4.8e-05 | 4.7e-04 | 1813 | 71 | 11 | BMP6,BMP8A,BTBD11,CCN3,GDF6,GDF9,HNF4A,INHBB,INHBC,JUN,MAGI2 |
| GO_REPLACEMENT_OSSIFICATION | 4.9e-05 | 4.9e-04 | 1813 | 28 | 7 | BMP6,CSGALNACT1,FGF18,FGFR3,MMP13,MMP16,PHOSPHO1 |
| GO_SYNAPTIC_MEMBRANE_ADHESION | 4.9e-05 | 4.9e-04 | 1813 | 28 | 7 | LRFN5,LRRC4C,MDGA1,NRXN1,NTNG2,SLITRK2,SLITRK3 |
| GO_LABYRINTHINE_LAYER_DEVELOPMENT | 5.0e-05 | 4.9e-04 | 1813 | 48 | 9 | FGFR2,GCM1,GRB2,HEY2,HS6ST1,PCDH12,PLCD1,SPINT1,VASH2 |
| GO_NEGATIVE_REGULATION_OF_BINDING | 5.0e-05 | 4.9e-04 | 1813 | 170 | 18 | ACE,CFHR1,CRMP1,EIF4A3,ENHO,EPB41L5,HEY2,JAK2,JUN,KDM1A,MRLN,MSX2,NES,NFATC4,NKX3-1,P2RY1,SLN,SYMPK |
| GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT | 5.0e-05 | 4.9e-04 | 1813 | 125 | 15 | ADCYAP1R1,AKAP6,ANXA9,ATP1B1,CACNA2D1,CACNB2,CASR,FGF14,GRIN1,HAP1,LILRA2,P2RX7,RGN,TRPV2,TRPV3 |
| GO_PRESYNAPSE_ORGANIZATION | 5.0e-05 | 4.9e-04 | 1813 | 48 | 9 | CBLN2,CLSTN3,IL1RAPL1,LRFN5,MDGA1,NRXN1,NTNG2,SLITRK2,SLITRK3 |
| GO_SMOOTH_MUSCLE_CONTRACTION | 5.1e-05 | 5.0e-04 | 1813 | 111 | 14 | ADRA1A,CD38,CHRNB2,CHRNB4,COMP,DRD2,FKBP1B,GUCY1A1,HTR2A,NMUR1,PTAFR,SSTR2,SULF2,TNNI3 |
Num: 4 (Pathways: 727 DK: 16)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (16) | CDK11A, CDK12, CDK17, CDKL1, CLK3, COQ8A, CSNK1G1, CSNK2A2, DYRK2, HIPK1, NEK7, PDIK1L, RIOK3, SCYL1, STK19, TLK2 |
| Light Kinase (41) | ABL2, ARAF, ATM, AURKB, BRD4, BTK, BUB1, CAMK2G, CDK1, CDK2, CHEK1, CLK1, DGKZ, FER, GRK7, GSK3A, GTF2F1, HKDC1, IRAK3, LYN, MAP2K7, MAP4K4, MAPK6, MAPK8, MASTL, MELK, MYLK2, NEK2, PAK1, PAK2, PLK4, RPS6KA5, SIK1, SIK1B, SMG1, SRPK1, STK10, STK35, TYRO3, WEE1, YES1 |
| Non-kinase Count | 1873 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 840 | 207 | AAR2,AGO2,AKAP8L,ALYREF,ATF4,ATM,BCAS2,BUD13,C9orf78,CACTIN,CASC3,CBLL1,CCNB1,CCNT1,CD2BP2,CDC40,CDK11A,CDK12,CELF1,CHERP,CIR1,CLASRP,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CPEB1,CPSF2,CPSF6,CPSF7,CSDE1,CWC22,CWC25,CWC27,CWF19L1,CWF19L2,DAZAP1,DCP1A,DCP2,DDX1,DHX34,DIS3,DKC1,EIF3E,ESS2,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FIP1L1,FMR1,FRG1,FXR1,GPATCH1,GRSF1,GSPT1,GTF2F1,GTF2H2,HNRNPA1,HNRNPA3,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPU,HNRNPUL1,HSF1,HSPA8,ISY1,JMJD6,KHDC4,KIN,LSM11,LSM8,LUC7L2,MAGOHB,MED1,MTPAP,NONO,NSRP1,NT5C3B,NUDT21,PABPC1,PABPC3,PABPN1,PAF1,PAIP1,PAPOLA,PATL2,PCBP2,PHF5A,POLDIP3,PPP4R2,PPWD1,PQBP1,PRCC,PRKRIP1,PRPF18,PRPF38A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUF60,PUM1,PUM2,PUS1,PUS7,RALY,RBBP6,RBM10,RBM15,RBM17,RBM22,RBM25,RBM26,RBM27,RBM39,RBM42,RBM4B,RBM7,RBM8A,RBMX,RBMX2,RBMXL2,RC3H1,RNF40,RNPS1,RPL21,RPL22,RPS7,SARNP,SART1,SART3,SCAF1,SCAF8,SCNM1,SET,SF1,SF3A2,SF3A3,SF3B2,SLBP,SLC11A1,SLTM,SLU7,SMG1,SMG5,SMG7,SMG8,SMG9,SMU1,SNIP1,SNRPA,SNRPA1,SNRPB,SNW1,SREK1,SREK1IP1,SRPK1,SRRT,SRSF11,SRSF4,SUPT6H,SUPV3L1,SYF2,TENT4A,TFIP11,THOC1,THOC5,U2AF1L5,U2SURP,UBB,UBC,UPF3B,VIRMA,WBP11,WDR83,XAB2,YJU2,YTHDF2,YTHDF3,ZC3H14,ZC3H3,ZC3HAV1,ZCCHC8,ZNF326,ZRSR2 |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 1864 | 299 | AATF,ABRAXAS2,ACTR3,ACTR8,AKAP8,AKAP8L,ANKLE2,ATF2,ATM,AURKB,AZI2,BABAM1,BAP1,BID,BIN1,BRCA2,BRD4,BUB1,C2CD3,CASP3,CCNA2,CCNB1,CCNB1IP1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK11A,CDK12,CDK17,CDK2,CDK5RAP3,CDKL1,CDT1,CENPA,CENPK,CENPQ,CENPT,CENPW,CEP120,CEP135,CEP55,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CHTF18,CKAP2,CKAP5,CLASP2,CLTA,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CNTROB,CRLF3,CSNK2A2,CSPP1,CUL1,CUL3,CUL4A,CUZD1,DDB1,DDX11,DMC1,DNM2,DOT1L,DRG1,DTL,DYNC1LI1,E2F3,E4F1,EDN1,EIF4G2,ESPL1,FANCI,FANCM,FBXL3,FBXO6,FBXO7,FBXW11,FEM1B,FER,FGFR1OP,FOXC1,GSPT1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HINFP,HJURP,HMMR,HNRNPU,HSF1,HUS1B,INCENP,INTS7,IPO7,IQGAP3,JTB,KIAA0753,KIF18A,KIF2C,KLF4,KLHDC3,KLHL18,KLHL21,KMT5A,KNSTRN,KPNB1,L3MBTL2,LIN54,LIN9,LSM11,MAPK6,MASTL,MCIDAS,MCM7,MCMDC2,MCPH1,MDM4,MECP2,MED1,MELK,MIS12,MIS18A,MND1,MNS1,MSH4,MTA3,MTBP,MUS81,MYO19,NAE1,NCAPH,NCAPH2,NCOR1,NDEL1,NEK2,NEK7,NME6,NOTCH1,NSFL1C,NSMCE2,NUDT15,NUF2,NUP43,NUP62,NUSAP1,ODF2,ORC6,PAF1,PARD3,PCM1,PCNP,PEA15,PES1,PGGT1B,PHB2,PHC3,PHF13,PHIP,PLK4,PMF1,PML,POLE,PPM1A,PPP1R15A,PRC1,PRCC,PRKAB1,PRR11,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC3IP,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,PTP4A1,PTPN11,PUM1,RAB35,RACGAP1,RAD1,RAD21,RAD51,RAD54L,RAE1,RAN,RASSF1,RBBP4,RBBP8,RBM7,RCC1,RCC2,RFC1,RFWD3,RIF1,RNASEH2B,RNF4,RPA2,RPA4,RRM1,SBDS,SDE2,SENP5,SENP6,SFN,SH2B1,SIK1,SIRT1,SLC25A33,SLC26A8,SLC38A9,SLF1,SMC1B,SMC4,SOX15,SPDYA,STAG1,STAG2,STARD9,STK10,SYF2,TAF2,TBRG1,TBX3,TCF7L2,TENT4A,TFDP2,THAP1,THAP5,THOC1,THOC5,TLK2,TNKS,TOP2A,TOP3A,TOPBP1,TPX2,TSC1,TUBA1C,TUBA8,TUBB,UBB,UBE2C,UBE2I,UHRF2,UIMC1,USP16,USP3,USP47,UVRAG,VPS4A,WAC,WAPL,WDR62,WEE1,YAF2,YTHDF2,YY1AP1,ZBTB49,ZC3HC1,ZFP42,ZNF16 |
| GO_RNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 917 | 201 | AAR2,ADAT2,AGO2,AKAP8L,ALKBH1,ALKBH8,ALYREF,BCAS2,BUD13,C1D,C9orf78,CACTIN,CASC3,CCNB1,CCNL1,CCNT1,CD2BP2,CDC40,CDK11A,CDK12,CDKAL1,CELF1,CHERP,CIR1,CLASRP,CLK1,CLK3,CNOT6L,CPEB1,CPSF2,CPSF6,CPSF7,CWC22,CWC25,CWC27,CWF19L1,CWF19L2,DAZAP1,DDX1,DDX52,DDX54,DIS3,DKC1,DUS3L,ESS2,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FCF1,FIP1L1,FMR1,FRG1,FXR1,GAR1,GPATCH1,GRSF1,GTF2F1,GTF2H2,HNRNPA1,HNRNPA3,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPU,HNRNPUL1,HSD17B10,HSF1,HSPA8,INTS7,ISY1,JMJD6,KHDC4,KIN,LSM11,LSM8,LUC7L2,MAGOHB,MRM3,MTERF4,MTPAP,NAF1,NCOR1,NOL9,NONO,NSA2,NSRP1,NSUN3,NUDT21,PABPC1,PABPN1,PAF1,PAPOLA,PCBP2,PES1,PHF5A,POLDIP3,POP7,PPIG,PPP4R2,PPWD1,PQBP1,PRCC,PRKRIP1,PRPF18,PRPF38A,PUF60,PUM1,PUM2,PUS1,PUS7,RALY,RBBP6,RBM10,RBM15,RBM17,RBM22,RBM25,RBM26,RBM27,RBM39,RBM42,RBM4B,RBM6,RBM7,RBM8A,RBMX,RBMX2,RBMXL2,RIOK3,RNF40,RNPS1,RPS7,RPUSD4,RRP1,RRP9,RTCA,SARNP,SART1,SART3,SBDS,SCAF1,SCAF8,SCNM1,SEPHS1,SF1,SF3A2,SF3A3,SF3B2,SLBP,SLTM,SLU7,SMU1,SNIP1,SNRPA,SNRPA1,SNRPB,SNW1,SREK1,SREK1IP1,SRFBP1,SRPK1,SRRT,SRSF11,SRSF4,SUPT6H,SUPV3L1,SYF2,TENT4A,TEX10,TFIP11,THOC1,THOC5,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TSR1,TSR2,TYW3,U2AF1L5,U2SURP,UPF3B,UTP18,VIRMA,WBP11,WDR4,WDR83,XAB2,YJU2,ZBTB8OS,ZC3H14,ZC3H3,ZC3H7A,ZCCHC4,ZCCHC8,ZNF326,ZRSR2 |
| GO_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1399 | 232 | ABRAXAS2,ACTR3,AKAP8,AKAP8L,ANKLE2,ATF2,ATM,AURKB,BABAM1,BID,BIN1,BRCA2,BRD4,BUB1,C2CD3,CCNA2,CCNB1,CCNB1IP1,CCNB2,CCNK,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK2,CDK5RAP3,CDT1,CENPA,CENPK,CENPQ,CENPW,CEP120,CEP135,CEP55,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CKAP5,CLASP2,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CNTROB,CRLF3,CSNK2A2,CSPP1,CUL1,CUL3,CUL4A,DDB1,DDX11,DMC1,DNM2,DRG1,DTL,DYNC1LI1,E4F1,EDN1,EIF4G2,ESPL1,FANCM,FBXL3,FBXO7,FBXW11,FGFR1OP,GSPT1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HINFP,HMMR,HNRNPU,HSF1,HUS1B,INCENP,IQGAP3,JTB,KIAA0753,KIF18A,KIF2C,KLF4,KLHDC3,KLHL18,KLHL21,KNSTRN,KPNB1,L3MBTL2,LSM11,MASTL,MCM7,MCMDC2,MCPH1,MDM4,MECP2,MED1,MELK,MIS12,MND1,MSH4,MTA3,MTBP,MUS81,MYO19,NAE1,NCAPH,NCAPH2,NCOR1,NDEL1,NEK2,NEK7,NME6,NOTCH1,NSFL1C,NSMCE2,NUF2,NUP62,NUSAP1,ODF2,ORC6,PAF1,PCM1,PHB2,PHC3,PHF13,PHIP,PLK4,PML,POLE,PPM1A,PPP1R15A,PRC1,PRCC,PRKAB1,PRR11,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC3IP,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RAB35,RACGAP1,RAD1,RAD21,RAD51,RAD54L,RAE1,RAN,RASSF1,RBBP4,RBBP8,RCC1,RCC2,RFC1,RFWD3,RNASEH2B,RNF4,RPA2,RPA4,SBDS,SDE2,SENP6,SFN,SH2B1,SLC25A33,SLC38A9,SLF1,SMC1B,SMC4,SOX15,SPDYA,STAG1,STAG2,STARD9,SYF2,TAF2,TBRG1,TCF7L2,TENT4A,TFDP2,TNKS,TOP2A,TOP3A,TOPBP1,TPX2,TUBB,UBB,UBE2C,UHRF2,UIMC1,USP16,USP47,UVRAG,VPS4A,WAPL,WDR62,WEE1,YAF2,YTHDF2,ZBTB49,ZNF16 |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 856 | 181 | AATF,ACD,ACTL6A,ACTR8,ALKBH1,ALKBH3,ALKBH8,AP5Z1,APTX,ASCC2,ATF2,ATM,ATMIN,ATXN3,BABAM1,BCL2L12,BCL2L2,BID,BRCA2,BRD4,CASP3,CCDC13,CCNB1,CCNK,CDC25C,CDCA5,CDK1,CDK2,CDK5RAP3,CDKN2AIP,CGAS,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,COPS2,COPS3,COPS7B,CUL4A,DDB1,DDX1,DDX11,DMC1,DNAJA1,DOT1L,DTL,DYRK2,EEF1E1,EID3,ERCC8,FANCG,FANCI,FANCM,FBXO6,FEM1B,FMR1,FXR1,GINS4,GTF2H2,GTF2H2C,H4-16,HELB,HIC1,HINFP,HIPK1,HMCES,HMGB2,HNRNPK,HSF1,HUS1B,IGHMBP2,INIP,INO80B,INO80D,INTS7,ISY1,KAT5,KDM2A,KIN,KMT5A,LYN,MARCHF7,MASTL,MBD4,MCM7,MCMDC2,MDM4,MMS22L,MRPS35,MSH4,MUS81,NEIL3,NONO,NPLOC4,NSD2,NSMCE2,NUCKS1,PAK1,PARP2,PAXX,PEA15,PHF1,PML,POLE,POLK,POLL,PPP1R15A,PPP4C,PPP4R2,PTPN11,RAD1,RAD18,RAD21,RAD51,RAD51AP1,RAD54L,RBBP6,RBBP8,RBM17,RCHY1,RECQL,RECQL4,RFC1,RFWD3,RIF1,RNASEH2A,RNASEH2B,RNF138,RPA2,RPA4,SFN,SHLD1,SHLD2,SIRT1,SLF1,SMG1,SNW1,SPDYA,SYF2,TAF9B,TDP2,TENT4A,TERF2IP,TFDP2,TFIP11,THOC1,THOC5,TLK2,TOP2A,TOPBP1,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2D3,UBE2T,UBQLN4,UFD1,UIMC1,UNG,USP1,USP16,USP3,USP47,USP7,UVRAG,WAC,WDR4,WDR48,XAB2,XIAP,XRCC4,YAP1,YJU2,YY1,ZBTB40 |
| GO_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 1223 | 214 | ACD,ACTL6A,ACTR6,ACTR8,AKAP8,AKAP8L,ANP32B,ANP32E,ATAD2,ATF2,ATM,AURKB,BABAM1,BAP1,BAZ2A,BRCA2,BRD1,BRD4,BRMS1,BRMS1L,BUB1,CCNA2,CCNB1,CCNB1IP1,CDC27,CDC6,CDCA5,CDK1,CDK2,CDT1,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,CHEK1,CHMP4B,CHMP5,CHTF18,COPS2,COPS3,COPS7B,CREBBP,CUL3,CUL4A,DAXX,DCAF1,DCP2,DDB1,DDX1,DDX11,DFFB,DKC1,DMC1,DNAJC2,DOT1L,DPF2,DR1,DYNC1LI1,ERCC8,ESPL1,EXOSC10,EZH1,FAM172BP,FMR1,GAR1,GINS4,GRWD1,GTF2H2,H1-4,H2BC3,H4-16,HAT1,HELB,HJURP,HMGB2,HNRNPA1,HNRNPU,HP1BP3,HUS1B,IGHMBP2,INCENP,ING3,INO80B,JMJD6,KANSL1,KANSL2,KAT5,KAT7,KDM2A,KDM6A,KDM6B,KIF18A,KIF2C,KMT2A,KMT2B,KMT5A,KNSTRN,KPNB1,L3MBTL2,LTO1,MAP2K7,MAPK8,MBIP,MCM7,MCMDC2,MCPH1,MECP2,METTL4,MIER1,MIS12,MIS18A,MSH4,MSL2,MSL3,MTA3,NAF1,NAP1L1,NAP1L4,NCAPH,NCAPH2,NCOR1,NEK2,NEK7,NSD2,NSD3,NSMCE2,NUCKS1,NUF2,NUP62,NUSAP1,PAF1,PAK1,PCGF5,PHB2,PHF1,PHF13,PML,POLE,PRC1,PRDM4,PSMG2,PWP1,RACGAP1,RAD21,RAD51,RAD54L,RAD54L2,RAE1,RAN,RBBP4,RECQL,RECQL4,RFC1,RFWD3,RIF1,RNF4,RNF40,RPA2,RPS6KA5,SART3,SENP6,SET,SETDB1,SIN3B,SIRT1,SLF1,SMAD4,SMC1B,SMC4,SMG1,SMG5,SMG7,SNW1,SOX15,SPTY2D1,SRPK1,STAG1,STAG2,SUPT6H,SUPT7L,SUPV3L1,TADA1,TADA2B,TAF5L,TAF9B,TCF7L2,TELO2,TENT4A,TERF2IP,TET3,TFIP11,TLK2,TNKS,TOP2A,TOP3A,TRIP12,UBB,UBC,UBE2A,UIMC1,USP16,USP21,USP3,USP7,VPS4A,WAC,WAPL,YY1,ZNF335,ZSCAN4 |
| GO_MRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 503 | 139 | AAR2,AKAP8L,ALYREF,BCAS2,BUD13,C9orf78,CACTIN,CASC3,CCNB1,CCNT1,CD2BP2,CDC40,CDK11A,CDK12,CELF1,CHERP,CIR1,CLASRP,CNOT6L,CPEB1,CPSF2,CPSF6,CPSF7,CWC22,CWC25,CWC27,CWF19L1,CWF19L2,DAZAP1,DDX1,ESS2,FIP1L1,FMR1,FRG1,FXR1,GPATCH1,GRSF1,GTF2F1,GTF2H2,HNRNPA1,HNRNPA3,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPU,HNRNPUL1,HSF1,HSPA8,ISY1,JMJD6,KHDC4,KIN,LSM11,LSM8,LUC7L2,MAGOHB,MTPAP,NONO,NSRP1,NUDT21,PABPC1,PABPN1,PAF1,PAPOLA,PCBP2,PHF5A,POLDIP3,PPP4R2,PPWD1,PQBP1,PRCC,PRKRIP1,PRPF18,PRPF38A,PUF60,RALY,RBBP6,RBM10,RBM15,RBM17,RBM22,RBM25,RBM26,RBM27,RBM39,RBM42,RBM4B,RBM7,RBM8A,RBMX,RBMX2,RBMXL2,RNF40,RNPS1,SARNP,SART1,SART3,SCAF1,SCAF8,SCNM1,SF1,SF3A2,SF3A3,SF3B2,SLBP,SLTM,SLU7,SMU1,SNIP1,SNRPA,SNRPA1,SNRPB,SNW1,SREK1,SREK1IP1,SRPK1,SRRT,SRSF11,SRSF4,SUPT6H,SYF2,TENT4A,TFIP11,THOC1,THOC5,U2AF1L5,U2SURP,UPF3B,VIRMA,WBP11,WDR83,XAB2,YJU2,ZC3H14,ZC3H3,ZCCHC8,ZNF326,ZRSR2 |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 1224 | 212 | AATF,ATF2,ATM,AURKB,BABAM1,BAP1,BID,BIN1,BRCA2,BRD4,BUB1,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK11A,CDK12,CDK17,CDK2,CDK5RAP3,CDKL1,CDT1,CEP120,CEP135,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP5,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CSNK2A2,CSPP1,CUL1,CUL3,CUL4A,DDB1,DDX11,DOT1L,DRG1,DTL,DYNC1LI1,E2F3,E4F1,EDN1,EIF4G2,ESPL1,FBXL3,FBXO6,FBXO7,FEM1B,FGFR1OP,FOXC1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HINFP,HMMR,HNRNPU,HSF1,HUS1B,INCENP,INTS7,IPO7,KLF4,KLHL18,KLHL21,KNSTRN,L3MBTL2,LIN54,LIN9,LSM11,MASTL,MCIDAS,MCPH1,MDM4,MECP2,MED1,MTA3,MTBP,MUS81,MYO19,NAE1,NEK2,NEK7,NME6,NOTCH1,NSFL1C,NSMCE2,NUP62,NUSAP1,ODF2,PAF1,PCM1,PEA15,PES1,PGGT1B,PHB2,PHC3,PHIP,PLK4,PML,PPM1A,PPP1R15A,PRC1,PRCC,PRKAB1,PRR11,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,PTPN11,PUM1,RACGAP1,RAD1,RAD21,RAD51,RAE1,RASSF1,RBBP4,RBBP8,RCC1,RCC2,RFWD3,RNASEH2B,RNF4,RPA2,RPA4,SDE2,SENP6,SFN,SH2B1,SIK1,SIRT1,SLC25A33,SLC38A9,SLF1,SOX15,SPDYA,STAG1,STAG2,SYF2,TBRG1,TBX3,TCF7L2,TFDP2,THAP1,THAP5,THOC1,THOC5,TNKS,TOP2A,TOPBP1,TPX2,TSC1,TUBB,UBE2C,UHRF2,UIMC1,USP16,USP47,UVRAG,VPS4A,WAC,WAPL,WEE1,YAF2,YTHDF2,YY1AP1,ZBTB49,ZNF16 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 1930 | 1114 | 201 | ABRAXAS2,ACTL6A,ACTR8,ADRM1,ARRDC3,ASB3,ASB7,ATXN3,AXIN1,BABAM1,BAG2,BAP1,BRAP,BTBD1,CBLL1,CCNA2,CCNB1IP1,CDC16,CDC25A,CDC27,CDK1,CDK5RAP3,CNOT4,COP1,COPS2,COPS3,COPS7B,CUL1,CUL3,CUL4A,DAXX,DCAF1,DCAF12,DCAF15,DCUN1D2,DDB1,DESI2,DMAC2,DNAJA1,DTL,DTX3,E4F1,EIF3F,ERCC8,FANCI,FANCM,FBXL3,FBXO11,FBXO2,FBXO30,FBXO6,FBXO7,FBXW11,FBXW2,FEM1B,FOXK2,GSK3A,H2BC3,HGS,INO80B,INO80D,ITCH,KBTBD8,KCMF1,KLHL18,KLHL21,LRRC41,MARCHF7,MASTL,MDM4,MED1,MED10,MED27,MED30,MED31,MINDY4,MKRN2,MSL2,MTBP,NAE1,NFE2L2,NMI,NSMCE2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OBI1,OTUD4,OTUD7B,PAF1,PCGF5,PCNP,PEF1,PEX14,PLAA,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAB1A,RAD18,RAE1,RANGAP1,RBBP6,RC3H1,RCE1,RCHY1,RFWD3,RLIM,RNF10,RNF126,RNF138,RNF19B,RNF25,RNF31,RNF38,RNF4,RNF40,RNF6,RNF7,RPS7,RUSC1,SART3,SDE2,SENP1,SENP5,SENP6,SENP7,SIRT1,SMAD4,SMURF1,SOCS6,SPOPL,STAM,SUMO2,SUMO3,TADA2B,TAF9B,TICAM1,TNIP2,TNKS,TRAF2,TRAIP,TRIM23,TRIM56,TRIP12,UBA2,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2M,UBE2T,UBE2Z,UBE3A,UFD1,UFL1,UHRF2,UIMC1,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,USPL1,WAC,WASHC1,WDR20,WDR48,XIAP,YY1,ZC3HC1,ZFP91,ZNF738,ZNRF3 |
| GO_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 1030 | 191 | AATF,ABRAXAS2,AKAP8,AKAP8L,ANKLE2,ATF2,ATM,AURKB,AZI2,BID,BRCA2,BRD4,BUB1,CCNA2,CCNB1,CCNB2,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK11A,CDK2,CDK5RAP3,CDT1,CENPA,CENPK,CENPT,CENPW,CEP135,CEP55,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CKAP2,CKAP5,CLASP2,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CNTROB,CRLF3,CUL1,CUL3,CUL4A,DDB1,DNM2,DRG1,DTL,DYNC1LI1,E4F1,EDN1,ESPL1,FBXL3,FBXO7,FBXW11,FER,FGFR1OP,FOXC1,GSPT1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HINFP,HMMR,HNRNPU,HSF1,HUS1B,INCENP,IQGAP3,JTB,KIF18A,KIF2C,KLF4,KLHL18,KNSTRN,KPNB1,LSM11,MASTL,MCIDAS,MCM7,MCPH1,MDM4,MECP2,MELK,MIS12,MTA3,MTBP,MUS81,NAE1,NCAPH,NCAPH2,NDEL1,NEK2,NEK7,NME6,NSFL1C,NSMCE2,NUDT15,NUF2,NUP62,NUSAP1,ODF2,ORC6,PCM1,PHB2,PHF13,PHIP,PLK4,PML,POLE,PRC1,PRCC,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,PTPN11,RAB35,RACGAP1,RAD21,RAD51,RAE1,RAN,RBBP8,RCC1,RCC2,RFWD3,RNASEH2B,RPA2,RPA4,RRM1,SBDS,SFN,SH2B1,SIK1,SIRT1,SLF1,SMC4,SPDYA,STAG1,STAG2,SYF2,TAF2,TENT4A,TFDP2,THAP1,TNKS,TOP2A,TOPBP1,TPX2,TUBA1C,TUBA8,TUBB,UBE2C,USP16,USP3,USP47,VPS4A,WAPL,WDR62,WEE1 |
| GO_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 925 | 178 | ACD,ACTL6A,ACTR8,ALKBH1,ALKBH3,ALYREF,AP5Z1,APTX,ASCC2,ATM,ATXN3,AURKB,BABAM1,BAZ2A,BRCA2,CASP3,CCNB1IP1,CDADC1,CDC6,CDCA5,CDK1,CDK2,CDT1,CGAS,CHEK1,CHTF18,CLCF1,COPS2,COPS3,COPS7B,CUL4A,DCAF1,DCP2,DDB1,DDX1,DDX11,DFFB,DKC1,DMC1,DNAJC2,DTL,EID3,ERCC8,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,FANCG,FANCI,FANCM,FBXO6,GAR1,GIN1,GINS4,GSK3A,GTF2H2,GTF2H2C,H1-4,H4-16,HELB,HINFP,HMGB2,HNRNPA1,HNRNPU,HSF1,HUS1B,IGHMBP2,INIP,INO80B,INO80D,ISY1,KAT5,KDM2A,KIN,KLF4,KLHDC3,KMT2A,KPNA2,KPNB1,LIN9,LTO1,MAP2K7,MBD4,MCM7,MCMDC2,MECP2,METTL4,MIS18A,MMS22L,MND1,MSH4,MUS81,NAF1,NEIL3,NEK2,NEK7,NONO,NPLOC4,NSD2,NSMCE2,NUCKS1,NUDT15,ORC6,OTUD4,PARP2,PAXX,PML,POLE,POLK,POLL,PPP4C,PPP4R2,PSMC3IP,RAD1,RAD18,RAD21,RAD51,RAD51AP1,RAD54L,RAN,RBBP8,RBM17,RCHY1,RECQL,RECQL4,RFC1,RFWD3,RIF1,RNASEH2A,RNF138,RPA2,RPA4,SH2B1,SHLD1,SHLD2,SIRT1,SLF1,SMG1,SMG5,SMG7,SUPT6H,SUPV3L1,TATDN2,TCF3,TCF7L2,TDP2,TELO2,TENT4A,TERF2IP,TET3,TFIP11,THOC1,TNKS,TOP2A,TOP3A,TOPBP1,TRIP12,UBB,UBC,UBE2A,UBE2D3,UBE2T,UBQLN4,UFD1,UHRF2,UIMC1,UNG,USP1,USP3,USP47,USP7,UVRAG,WDR48,XAB2,XRCC4,YY1,ZSCAN4 |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1180 | 201 | ADRM1,AGO2,AP2B1,ARAF,ATM,ATXN3,AUP1,AURKB,AXIN1,BAG2,BAP1,CAPN2,CASC3,CASP3,CCNB1,CDC16,CDC27,CDK1,CDK2,CDK5RAP3,CHMP4B,CLN6,CLPP,CLTA,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,COP1,COPS3,CSDE1,CSNK2A2,CTSL,CUL1,CUL3,CUL4A,DCP1A,DCP2,DDA1,DDB1,DERL2,DFFB,DHX34,DIS3,DKC1,DMAC2,DNAJB14,DTL,ECPAS,EIF3E,ERCC8,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,FMR1,FXR1,GRSF1,GSK3A,GSPT1,HMGB2,HNRNPU,HSF1,HSP90B2P,HSPA8,ITCH,KAT5,KPNB1,MAGOHB,MARCHF7,MTPAP,MUS81,NAF1,NFE2L2,NPLOC4,NSFL1C,NT5C3B,NUDT15,OTUD7B,PABPC1,PAIP1,PATL2,PCBP2,PCNP,PDCL3,PLAA,PML,POMT2,PPP2CB,PRPF18,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,PUM1,PUM2,RBBP6,RBM10,RBM7,RBM8A,RC3H1,RCHY1,RLIM,RNASEH2A,RNASEH2B,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RNPS1,RPL21,RPL22,RPS7,SENP1,SET,SIRT1,SLC11A1,SMG1,SMG5,SMG7,SMG8,SMG9,SMURF1,SNX5,SOCS6,SPOPL,SUMO2,SUPV3L1,TENT4A,TLK2,TMEM199,TMUB2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,UPF3B,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,VPS35,VPS37A,VPS4A,WAC,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZCCHC8,ZFAND2A,ZNRF3 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1410 | 215 | ABHD17B,ADRM1,AGO2,AP2B1,ARAF,ATM,ATXN3,AUP1,AURKB,AXIN1,AZIN1,BAG2,BAG3,BAP1,BCAN,CAPN2,CASC3,CASP3,CCNB1,CDC16,CDC27,CDK1,CDK2,CDK5RAP3,CHMP4B,CLN6,CLPP,CLTA,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,COP1,COPS3,CSDE1,CSNK2A2,CTSL,CUL1,CUL3,CUL4A,DCP1A,DCP2,DDA1,DDB1,DERL2,DFFB,DHX34,DIS3,DKC1,DMAC2,DNAJB14,DTL,ECPAS,EGLN2,EIF3E,ERCC8,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,FMR1,FXR1,GRSF1,GSK3A,GSPT1,HGS,HMGB2,HMMR,HNRNPU,HSF1,HSP90B2P,HSPA8,IRAK3,ITCH,KAT5,KPNB1,MAGOHB,MARCHF7,MDM4,MTMR2,MTPAP,MUS81,NAF1,NFE2L2,NPLOC4,NSFL1C,NT5C3B,NUDT15,OAZ3,OTUD7B,PABPC1,PAIP1,PATL2,PCBP2,PCNP,PDCL3,PLAA,PML,POMT2,PPP2CB,PRPF18,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,PUM1,PUM2,RBBP6,RBM10,RBM7,RBM8A,RC3H1,RCHY1,RHBDD3,RLIM,RNASEH2A,RNASEH2B,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RNPS1,RPL21,RPL22,RPS7,SENP1,SET,SIRT1,SLC11A1,SMG1,SMG5,SMG7,SMG8,SMG9,SMURF1,SNX5,SOCS6,SPOPL,SUMO2,SUPV3L1,TENT4A,TLK2,TMEM199,TMUB2,TRAF2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,UPF3B,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,UVRAG,VPS35,VPS37A,VPS4A,WAC,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZCCHC8,ZFAND2A,ZNRF3 |
| GO_RNA_SPLICING | 0.0e+00 | 0.0e+00 | 1930 | 433 | 118 | AAR2,AKAP8L,ALYREF,BCAS2,BUD13,C9orf78,CACTIN,CASC3,CD2BP2,CDC40,CDK12,CELF1,CHERP,CIR1,CLASRP,CLK1,CLK3,CPSF2,CPSF7,CWC22,CWC25,CWC27,CWF19L1,CWF19L2,DAZAP1,DDX1,ESS2,FIP1L1,FMR1,FRG1,FXR1,GPATCH1,GTF2F1,HNRNPA1,HNRNPA3,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPU,HNRNPUL1,HSPA8,ISY1,JMJD6,KHDC4,LSM8,LUC7L2,MAGOHB,NONO,NSRP1,NUDT21,PABPC1,PABPN1,PAPOLA,PCBP2,PHF5A,PPIG,PPP4R2,PPWD1,PQBP1,PRCC,PRKRIP1,PRPF18,PRPF38A,PUF60,RALY,RBM10,RBM15,RBM17,RBM22,RBM25,RBM39,RBM42,RBM4B,RBM7,RBM8A,RBMX,RBMX2,RBMXL2,RNPS1,SART1,SART3,SCAF1,SCNM1,SF1,SF3A2,SF3A3,SF3B2,SLU7,SMU1,SNIP1,SNRPA,SNRPA1,SNRPB,SNW1,SREK1,SREK1IP1,SRPK1,SRRT,SRSF11,SRSF4,SUPT6H,SYF2,TFIP11,THOC1,THOC5,U2AF1L5,U2SURP,UPF3B,VIRMA,WBP11,WDR83,XAB2,YJU2,ZBTB8OS,ZCCHC8,ZNF326,ZRSR2 |
| GO_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 790 | 152 | ATM,AURKB,BABAM1,BID,BIN1,BRCA2,BRD4,BUB1,CCNB1,CCNK,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK2,CDK5RAP3,CDT1,CEP120,CEP135,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP5,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CSNK2A2,CSPP1,CUL1,CUL3,CUL4A,DDB1,DDX11,DRG1,DTL,DYNC1LI1,E4F1,EDN1,ESPL1,FBXO7,FGFR1OP,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HMMR,HNRNPU,HUS1B,INCENP,KLF4,KLHL18,KLHL21,KNSTRN,L3MBTL2,LSM11,MCPH1,MDM4,MECP2,MED1,MTA3,MTBP,MYO19,NAE1,NEK2,NME6,NSFL1C,NSMCE2,NUP62,NUSAP1,ODF2,PAF1,PCM1,PHB2,PHC3,PHIP,PLK4,PML,PRC1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RACGAP1,RAD1,RAD21,RAD51,RAE1,RBBP4,RBBP8,RCC1,RCC2,RFWD3,RNASEH2B,RNF4,RPA2,SDE2,SENP6,SFN,SH2B1,SLC25A33,SLF1,SOX15,STAG1,STAG2,SYF2,TFDP2,TNKS,TOPBP1,TPX2,TUBB,UBE2C,UHRF2,UIMC1,USP47,UVRAG,VPS4A,WAPL,WEE1,YAF2,YTHDF2,ZNF16 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 0.0e+00 | 1930 | 912 | 157 | ARRDC3,ASB3,ASB7,AXIN1,BAG2,BRAP,BTBD1,CBLL1,CCNB1IP1,CDC16,CDC27,CDK5RAP3,CNOT4,COP1,CUL1,CUL3,CUL4A,DAXX,DCAF1,DCAF12,DCAF15,DCUN1D2,DDB1,DMAC2,DNAJA1,DTL,DTX3,E4F1,ERCC8,FANCI,FANCM,FBXL3,FBXO11,FBXO2,FBXO30,FBXO6,FBXO7,FBXW11,FBXW2,FEM1B,GSK3A,H2BC3,ITCH,KBTBD8,KCMF1,KLHL18,KLHL21,LRRC41,MARCHF7,MASTL,MED1,MED10,MED27,MED30,MED31,MKRN2,MSL2,MTBP,NAE1,NFE2L2,NMI,NSMCE2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OBI1,PAF1,PCGF5,PCNP,PEF1,PEX14,PLAA,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAB1A,RAD18,RAE1,RANGAP1,RBBP6,RC3H1,RCHY1,RFWD3,RLIM,RNF10,RNF126,RNF138,RNF19B,RNF25,RNF31,RNF38,RNF4,RNF40,RNF6,RNF7,RPS7,RUSC1,SDE2,SENP1,SENP5,SENP6,SIRT1,SMURF1,SOCS6,SPOPL,SUMO2,SUMO3,TICAM1,TNKS,TRAF2,TRAIP,TRIM23,TRIM56,TRIP12,UBA2,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2M,UBE2T,UBE2Z,UBE3A,UFL1,UHRF2,USP7,WAC,WASHC1,WDR48,XIAP,ZC3HC1,ZFP91,ZNF738,ZNRF3 |
| GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS | 0.0e+00 | 0.0e+00 | 1930 | 345 | 98 | AAR2,ALYREF,BCAS2,BUD13,C9orf78,CACTIN,CASC3,CD2BP2,CDC40,CELF1,CHERP,CPSF2,CPSF7,CWC22,CWC25,CWC27,CWF19L1,CWF19L2,DAZAP1,DDX1,ESS2,FIP1L1,FMR1,FRG1,FXR1,GPATCH1,GTF2F1,HNRNPA1,HNRNPA3,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPU,HNRNPUL1,HSPA8,ISY1,JMJD6,KHDC4,LSM8,LUC7L2,MAGOHB,NSRP1,NUDT21,PABPC1,PABPN1,PAPOLA,PCBP2,PHF5A,PPWD1,PQBP1,PRCC,PRPF18,PRPF38A,PUF60,RALY,RBM10,RBM15,RBM17,RBM22,RBM25,RBM42,RBM4B,RBM7,RBM8A,RBMX,RBMX2,RBMXL2,RNPS1,SART1,SART3,SCNM1,SF1,SF3A2,SF3A3,SF3B2,SLU7,SMU1,SNIP1,SNRPA,SNRPA1,SNRPB,SNW1,SREK1,SRPK1,SRRT,SRSF11,SRSF4,SYF2,TFIP11,U2AF1L5,U2SURP,UPF3B,WBP11,WDR83,XAB2,ZCCHC8,ZRSR2 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1870 | 231 | AATF,ACD,ACTL6A,ACTR3,AGO2,AKAP8L,ALYREF,ANKRD49,ATAD2,ATF1,ATF2,ATF4,ATM,ATMIN,AURKB,AXIN1,BABAM1,BCL2L12,BRCA2,BRD4,CCNA2,CCNB1,CCNK,CCNT1,CCNT2,CDK12,CDK2,CDK5RAP3,CHEK1,CHTF18,CKAP2,CLCF1,CNOT6,CNOT6L,CNOT9,CPEB1,CREB1,CREBBP,CRLF3,CRTC3,CTBP2,DAXX,DAZAP1,DDX11,DKC1,DNAJC2,DNM2,DOT1L,DPF2,DR1,DVL3,E2F3,E4F1,EDN1,EIF2A,ELF2,ELF5,ELK1,ELL,ERCC8,EXOSC3,EXOSC9,EZH1,FBXW11,FOXC1,FOXJ2,FOXJ3,FOXK2,FUBP3,GALR2,GMEB1,GMEB2,GPATCH3,GPBP1L1,GRSF1,GSK3A,GTF2F1,H1-4,HINFP,HMGB2,HNRNPA1,HNRNPK,HNRNPU,HOXA11,HOXA9,HOXC11,HSF1,HSF2,ILF3,JMJD6,KAT5,KAT7,KDM6B,KLF4,KMT2A,KMT2B,MAFG,MAP2K7,MCIDAS,MECP2,MED1,MED10,MED13,MED17,MED27,MED30,MED31,MED6,MLLT10,MTA3,NAF1,NEK2,NEK7,NFE2L2,NFKB1,NFKBIB,NFYC,NHLH1,NOTCH1,NR2C2,NRF1,NRL,NSD2,NSD3,NUCKS1,NUDT21,NUP62,OTUD4,PABPC1,PAF1,PBX3,PCGF5,PFKFB3,PHF1,PHF5A,PHIP,PKNOX1,PLAGL2,PMF1,PML,PPM1A,PPP3R1,PPRC1,PQBP1,PRDM4,PSMC2,PSMC3,PSMC3IP,PSMC4,PSMC6,PTOV1,PUM1,PWP1,RAD51,RAN,RAP2C,RBM15,RBM22,RBMX,RC3H1,REL,RFC1,RIF1,RNF10,RNF4,RNF6,RPS6KA5,SCAF8,SENP1,SHLD1,SHLD2,SIRT1,SIX4,SLC11A1,SLF1,SMAD4,SNW1,SOX15,SP3,SUMO2,SUPT6H,SUPT7L,SUPV3L1,TADA1,TADA2B,TAF2,TAF5L,TAF9B,TBR1,TBX3,TCERG1,TCF20,TCF3,TCF7L2,TEAD4,TET3,TFDP2,THOC1,THOC5,TNIP2,TNKS,TOP2A,UBB,UBC,UBE3A,UIMC1,USP16,USP21,USP7,WAC,YAF2,YAP1,YES1,YTHDF2,YTHDF3,YY1,ZBTB49,ZC3HAV1,ZEB1,ZEB2,ZNF131,ZNF148,ZNF24,ZNF300,ZNF382,ZNF496,ZNF597,ZNF613,ZNF639,ZNF649,ZNF835 |
| GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 664 | 131 | AATF,ATF2,ATM,AURKB,BID,BRCA2,BRD4,BUB1,CCNB1,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK2,CDK5RAP3,CDT1,CEP135,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CKAP5,CLTC,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL1,CUL3,CUL4A,DDB1,DRG1,DTL,DYNC1LI1,E4F1,EDN1,ESPL1,FBXO7,FGFR1OP,FOXC1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HMMR,HNRNPU,HSF1,HUS1B,INCENP,KLF4,KLHL18,LSM11,MCIDAS,MCPH1,MDM4,MECP2,MTA3,MTBP,MUS81,NAE1,NEK2,NEK7,NME6,NSFL1C,NSMCE2,NUP62,NUSAP1,ODF2,PCM1,PHB2,PHIP,PLK4,PML,PRCC,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,PTPN11,RAD21,RAE1,RCC1,RCC2,RFWD3,RNASEH2B,RPA2,SFN,SH2B1,SIK1,SIRT1,SLF1,STAG1,STAG2,SYF2,TFDP2,THAP1,TNKS,TOP2A,TOPBP1,TPX2,TUBB,UBE2C,USP47,VPS4A,WEE1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1988 | 232 | AATF,ACD,ACTL6A,ACTR3,AGO2,AKAP8L,ALYREF,ANKRD49,ATAD2,ATF1,ATF2,ATF4,ATM,ATMIN,AURKB,AXIN1,BCL2L12,BRCA2,BRD4,CAPN2,CCNA2,CCNK,CCNT1,CCNT2,CDK1,CDK12,CDK2,CDK5RAP3,CDT1,CHEK1,CHTF18,CKAP2,CNOT6,CNOT9,CREB1,CREBBP,CRLF3,CRTC3,CTBP2,DAXX,DDB1,DDX11,DKC1,DNAJC2,DNM2,DOT1L,DPF2,DR1,DVL3,DYRK2,E2F3,E4F1,EDN1,EIF2A,EIF2S3B,EIF3E,EIF5A,ELF2,ELF5,ELK1,ELL,EXOSC9,EZH1,FAF1,FBXW11,FMR1,FOXC1,FOXJ2,FOXJ3,FOXK2,FUBP3,FXR1,GALR2,GMEB1,GMEB2,GPATCH3,GPBP1L1,GSK3A,GTF2F1,H1-4,HINFP,HMGB2,HNRNPA1,HNRNPK,HNRNPL,HNRNPU,HOXA11,HOXA9,HOXC11,HSF1,HSF2,ILF3,JMJD6,KAT5,KAT7,KDM6B,KLF4,KMT2A,KMT2B,MAFG,MAP2K7,MCIDAS,MECP2,MED1,MED10,MED13,MED17,MED27,MED30,MED31,MED6,MLLT10,MTA3,NAF1,NEK2,NEK7,NFE2L2,NFKB1,NFKBIB,NFYC,NGRN,NHLH1,NOTCH1,NR2C2,NRF1,NRL,NSD3,NUCKS1,NUP62,PABPC1,PAF1,PAIP1,PAWR,PBX3,PCGF5,PHF1,PHF5A,PHIP,PKNOX1,PLAGL2,PMF1,PML,POLDIP3,POMT2,PPM1A,PPP1R15A,PPP3R1,PPRC1,PQBP1,PRDM4,PSMC2,PSMC3,PSMC3IP,PSMC4,PSMC6,PTOV1,PWP1,RAB38,RAB3GAP1,RAN,RAP2C,RBM15,RBMX,REL,RFC1,RNF10,RNF4,RNF6,RPS6KA5,RPUSD4,SCAF8,SENP1,SIRT1,SIX4,SLC11A1,SMAD4,SNW1,SOX15,SP3,STOML2,SUMO2,SUPT6H,SUPT7L,TADA1,TADA2B,TAF2,TAF5L,TAF9B,TBR1,TBX3,TCERG1,TCF20,TCF3,TCF7L2,TEAD4,TET3,TFDP2,THOC1,THOC5,TICAM1,TNIP2,TNKS,TOP2A,UBB,UBC,UBE3A,UPF3B,USP16,USP21,VPS35,WAC,YAF2,YAP1,YES1,YTHDF2,YTHDF3,YY1,ZBTB49,ZCCHC4,ZEB1,ZEB2,ZNF131,ZNF148,ZNF24,ZNF300,ZNF382,ZNF496,ZNF597,ZNF613,ZNF639,ZNF649,ZNF835 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1470 | 194 | ACD,ATAD2,ATF2,ATM,ATXN1L,AURKB,BAG3,BAP1,BAZ2A,BCL7A,BRMS1,BRMS1L,C11orf95,C1D,CCNT1,CDK2,CGAS,CHCHD3,CIR1,CNOT2,COPS2,CREB1,CREBBP,CREBZF,CTBP2,CUL3,DAXX,DCAF1,DCP2,DDX54,DEPDC1,DHX34,DKC1,DNAJB1,DNAJB6,DNAJC2,DOT1L,DPF2,DR1,E2F3,E4F1,EDN1,EXOSC10,EZH1,FAM172BP,FBXW11,FMR1,FOXC1,FOXK2,GSK3A,H1-4,H4-16,HAT1,HELB,HIC1,HINFP,HMGB2,HNRNPA1,HNRNPK,HNRNPL,HNRNPU,HSF1,HSPA8,IGHMBP2,ILF3,KAT5,KAT7,KDM2A,KLF4,KMT2A,KMT5A,LANCL2,LRRFIP1,MAF1,MCPH1,MDM4,MECP2,MED1,MIER1,MIER3,MSL3,MTA3,MXD1,N4BP2L2,NAB1,NAF1,NCOR1,NELFA,NFKB1,NKAP,NONO,NOTCH1,NSD2,OTUD7B,PABPC1,PAF1,PAIP1,PAWR,PER3,PEX14,PFDN5,PHB2,PML,PPM1A,RBBP8,RBM10,RBM42,RBMX,RCOR3,REL,RFC1,RIF1,RLIM,RNF40,RNPS1,RPS6KA5,SARNP,SCAF4,SCAF8,SCAI,SET,SETDB1,SF1,SHLD1,SHLD2,SIN3B,SIRT1,SIX4,SLC11A1,SMAD4,SNW1,SOX15,SP3,SPINDOC,SRSF4,STRN3,TAF9B,TBPL2,TBR1,TBX3,TCERG1,TCF3,TCF7L2,TDP2,TENT4A,TERF2IP,TFDP2,TFIP11,THAP1,THOC1,TNKS,TRIP12,UBB,UBC,UBE2D3,UBE2I,UBQLN4,UIMC1,USP3,USP47,YAF2,YAP1,YY1,ZBTB14,ZBTB2,ZBTB26,ZBTB33,ZBTB34,ZC3H14,ZEB1,ZEB2,ZNF131,ZNF136,ZNF140,ZNF148,ZNF157,ZNF165,ZNF189,ZNF202,ZNF215,ZNF24,ZNF263,ZNF296,ZNF382,ZNF568,ZNF597,ZNF613,ZNF639,ZNF649,ZNF668,ZNF675,ZNF835,ZNF85,ZSCAN4 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1930 | 1779 | 216 | ABRAXAS2,ACTL6A,ACTR8,ADAMTS6,ADRM1,ALG13,ANP32B,APH1A,ARAF,ARL6IP1,ATXN3,AUP1,AURKB,AXIN1,BABAM1,BAG2,BAP1,BCL2L12,BID,BIN1,C2CD3,CAPN10,CAPN2,CAPN7,CASP10,CASP3,CASP7,CCNA2,CCNB1,CDC16,CDC25A,CDC27,CDK1,CDK2,CHMP4B,CLDN4,CLN6,CLPP,CNOT4,COA8,COL6A3,COP1,COPS2,COPS3,COPS7B,CPAMD8,CSNK2A2,CTSL,CUL1,CUL3,CUL4A,CUZD1,DDA1,DDB1,DERL2,DESI2,DMAC2,DNAJB14,DNAJB6,DPP10,DPP7,DPP9,DTL,ECPAS,EIF3F,EIF3H,ERAP1,ERCC8,ERO1B,ESPL1,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,FBXW2,FMR1,FOXK2,GSK3A,HGS,HMCES,HSF1,HSP90B2P,INO80B,INO80D,INPP5B,ITCH,KAT5,KHDC1L,KLF4,LVRN,LYN,MARCHF7,MDM4,MEP1B,MINDY4,MTCH1,NDEL1,NFE2L2,NFKB1,NPEPPSP1,NPLOC4,NRIP3,NSFL1C,NUDT15,OTUD4,OTUD7B,PAK2,PCBP2,PCNP,PDCL3,PLAA,PML,PMPCB,POMT2,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,RBBP6,RBMX,RCE1,RCHY1,RHBDD3,RLIM,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RPS7,SART3,SDE2,SEC11A,SENP1,SENP5,SENP6,SENP7,SERPINC1,SFN,SIRT1,SMAD4,SMURF1,SOCS6,SPCS2,SPINK5,SPOPL,STAM,STOML2,SUMO2,TADA2B,TAF9B,TLK2,TMUB2,TNFRSF10A,TNIP2,TRAF2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,UIMC1,UQCRC2,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,USPL1,VPS37A,VPS4A,WAC,WDR20,WDR48,XIAP,YY1,ZFAND2A,ZNRF3,ZUP1 |
| GO_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 1930 | 551 | 115 | ACTL6A,ACTR8,ALKBH1,ALKBH3,AP5Z1,APTX,ASCC2,ATM,ATXN3,BABAM1,BRCA2,CDCA5,CDK1,CDK2,CGAS,CHEK1,COPS2,COPS3,COPS7B,CUL4A,DDB1,DDX1,DDX11,DMC1,DTL,EID3,ERCC8,FANCG,FANCI,FANCM,FBXO6,GINS4,GTF2H2,GTF2H2C,H4-16,HELB,HINFP,HMGB2,HSF1,HUS1B,IGHMBP2,INIP,INO80B,INO80D,ISY1,KAT5,KDM2A,KIN,MBD4,MCM7,MCMDC2,MMS22L,MSH4,MUS81,NEIL3,NONO,NPLOC4,NSD2,NSMCE2,NUCKS1,PARP2,PAXX,PML,POLE,POLK,POLL,PPP4C,PPP4R2,RAD1,RAD18,RAD21,RAD51,RAD51AP1,RAD54L,RBBP8,RBM17,RCHY1,RECQL,RECQL4,RFC1,RFWD3,RIF1,RNASEH2A,RNF138,RPA2,RPA4,SHLD1,SHLD2,SIRT1,SLF1,SMG1,TDP2,TENT4A,TERF2IP,TFIP11,TOPBP1,TRIP12,UBB,UBC,UBE2A,UBE2D3,UBE2T,UBQLN4,UFD1,UIMC1,UNG,USP1,USP3,USP47,USP7,UVRAG,WDR48,XAB2,XRCC4,YY1 |
| GO_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 637 | 123 | AKAP8,AKAP8L,ATM,AURKB,BABAM1,BID,BRD4,BUB1,CCNA2,CCNB1,CCNB2,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK2,CDK5RAP3,CDT1,CEP135,CEP57,CEP72,CEP76,CHEK1,CHMP4B,CKAP5,CLASP2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CUL1,CUL3,CUL4A,DDB1,DNM2,DTL,DYNC1LI1,ESPL1,FBXL3,FBXO7,FBXW11,FGFR1OP,GSPT1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HINFP,HMMR,HUS1B,IQGAP3,KLF4,KLHL18,LSM11,MASTL,MCM7,MDM4,MECP2,MELK,MTA3,MTBP,NAE1,NEK2,NSMCE2,ODF2,ORC6,PAF1,PCM1,PHB2,PLK4,PML,POLE,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RAD21,RBBP8,RCC1,RCC2,RFWD3,RNASEH2B,RPA2,RPA4,SFN,SPDYA,SYF2,TAF2,TFDP2,TOPBP1,TPX2,TUBB,UBE2C,UIMC1,USP47,VPS4A,WEE1,ZNF16 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1710 | 209 | AATF,ACTL6A,ACTR3,AGO2,AKAP8L,ALYREF,ANKRD49,ATAD2,ATF1,ATF2,ATF4,ATM,ATMIN,AXIN1,BCL2L12,BRCA2,BRD4,CCNA2,CCNB1,CCNK,CCNT1,CCNT2,CDK12,CDK2,CDK5RAP3,CHEK1,CKAP2,CNOT6,CNOT6L,CNOT9,CPEB1,CREB1,CREBBP,CRLF3,CRTC3,CTBP2,DAXX,DAZAP1,DDX11,DNAJC2,DNM2,DOT1L,DPF2,DR1,DVL3,E2F3,E4F1,EDN1,EIF2A,ELF2,ELF5,ELK1,ELL,EXOSC9,EZH1,FBXW11,FOXC1,FOXJ2,FOXJ3,FOXK2,FUBP3,GALR2,GMEB1,GMEB2,GPATCH3,GPBP1L1,GRSF1,GSK3A,GTF2F1,H1-4,HINFP,HMGB2,HNRNPK,HNRNPU,HOXA11,HOXA9,HOXC11,HSF1,HSF2,ILF3,JMJD6,KAT5,KAT7,KDM6B,KLF4,KMT2A,KMT2B,MAFG,MAP2K7,MCIDAS,MECP2,MED1,MED10,MED13,MED17,MED27,MED30,MED31,MED6,MLLT10,MTA3,NFE2L2,NFKB1,NFKBIB,NFYC,NHLH1,NOTCH1,NR2C2,NRF1,NRL,NSD3,NUCKS1,NUDT21,NUP62,PABPC1,PAF1,PBX3,PCGF5,PHF1,PHF5A,PHIP,PKNOX1,PLAGL2,PMF1,PML,PPM1A,PPP3R1,PPRC1,PQBP1,PRDM4,PSMC2,PSMC3,PSMC3IP,PSMC4,PSMC6,PTOV1,PUM1,PWP1,RAN,RAP2C,RBM15,RBM22,RBMX,RC3H1,REL,RFC1,RNF10,RNF4,RNF6,RPS6KA5,SCAF8,SENP1,SIRT1,SIX4,SLC11A1,SMAD4,SNW1,SOX15,SP3,SUMO2,SUPT6H,SUPT7L,SUPV3L1,TADA1,TADA2B,TAF2,TAF5L,TAF9B,TBR1,TBX3,TCERG1,TCF20,TCF3,TCF7L2,TEAD4,TET3,TFDP2,THOC1,THOC5,TNIP2,TNKS,TOP2A,UBB,UBC,UBE3A,USP16,USP21,WAC,YAF2,YAP1,YES1,YTHDF2,YTHDF3,YY1,ZBTB49,ZC3HAV1,ZEB1,ZEB2,ZNF131,ZNF148,ZNF24,ZNF300,ZNF382,ZNF496,ZNF597,ZNF613,ZNF639,ZNF649,ZNF835 |
| GO_REGULATION_OF_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 325 | 89 | AGO2,C9orf78,CCNB1,CCNT1,CDK11A,CELF1,CNOT6L,CPEB1,CPSF6,CPSF7,CWC22,DAZAP1,DCP1A,DCP2,DHX34,DIS3,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FMR1,FXR1,HNRNPA1,HNRNPK,HNRNPL,HNRNPU,HSF1,HSPA8,JMJD6,NSRP1,NUDT21,PABPC1,PABPN1,PAF1,PAIP1,PAPOLA,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RBM10,RBM15,RBM17,RBM25,RBM42,RBM4B,RBM7,RBM8A,RBMX,RC3H1,RNF40,RNPS1,SART3,SET,SLC11A1,SLTM,SMU1,SNRPA,SNW1,SREK1,SRPK1,SRSF4,SUPT6H,TENT4A,UBB,UBC,VIRMA,YTHDF2,YTHDF3,ZC3H14,ZC3H3,ZC3HAV1 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 1782 | 211 | AAR2,ABCA1,ABITRAM,ACTR3,ADRM1,AGO2,AIDA,AKR1C1,ANP32B,AP2B1,ATF1,ATM,AXIN1,BAG4,BAIAP2L1,BAZ2A,BID,BIN1,BRF2,BRIX1,CAMSAP1,CCNB1,CD2BP2,CD3G,CDK1,CDT1,CELF1,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,CEP57,CHMP4B,CKAP5,CLASP2,CLINT1,CLPP,CLTA,CLTB,CLTC,CNIH1,COA6,COA8,COPS7B,COX19,COX20,CPSF6,CPSF7,CREB1,CREBBP,CRTC3,CUL1,CUL3,CUL4A,DAXX,DDB1,DDX1,DENR,DFFB,DIAPH3,DMAC2,DMC1,DNAJB14,DR1,DRG1,ECPAS,ECSIT,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4B,EIF5,FAF1,FER,GRWD1,GTF2H2,GTF3C3,H1-4,H2BC3,H4-16,HAT1,HDGFL3,HJURP,HMGB2,HP1BP3,HSCB,HSD17B10,HSF1,HSPA8,ISY1,JMJD6,KAT5,KCTD14,KHDC4,KLHL21,KMT2A,LCP1,LPXN,LUC7L2,MATN1,MCM7,MCMDC2,MDM4,MECP2,MED6,MIS12,MIS18A,MTPN,NAF1,NAP1L1,NAP1L4,NCKAP1,NDEL1,NDUFA10,NDUFA9,NDUFAF6,NDUFS3,NDUFS7,NDUFS8,NSG1,NUDT21,NUP153,NUP205,NUP62,PAK1,PARD3,PDCL,PEF1,PEX14,PLAGL2,PML,POMP,PPAN,PPM1A,PPP6R1,PRKAB1,PRPF18,PSMC2,PSMC3,PSMC4,PSMC6,PSMG2,PTPN11,RAB1A,RAD51,RBBP4,RBMX,RCC1,RICTOR,RIOK3,RNF4,RPA2,RRM1,SAMM50,SAR1A,SART1,SART3,SEC24B,SEC24C,SENP6,SET,SF1,SF3A2,SF3A3,SLAIN2,SLC25A33,SLF1,SLU7,SMAD4,SNRPB,SPTY2D1,SRPK1,ST13,STOML2,SYT1,TBPL2,TCF7L2,TFIP11,TICAM1,TMED2,TMEM170A,TMEM199,TRAF2,TRAPPC10,TSC1,TWF1,UBB,UBC,UBE2C,UBE2K,UGDH,USP16,UVRAG,VAMP7,VBP1,VDAC2,VPS35,WASH3P,WASH6P,WASHC1,XAB2,YAP1,ZNF148,ZRSR2 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 1741 | 208 | ABCA1,ACAP2,ACD,AFTPH,AKAP8L,ALYREF,ANP32B,AP1G1,AP2B1,AP3B1,AP4S1,AP5Z1,ARCN1,ARL6IP1,ATP5F1B,ATP5MG,ATP5PB,AUP1,BAAT,BAG3,BAG4,BAP1,BID,BIN1,BLOC1S2,BTK,C12orf4,CAPN10,CASC3,CDC40,CEP120,CHMP4B,CHMP5,CLTA,CLTB,CLTC,CNIH1,CPSF2,CPSF6,CSNK2A2,CTDSPL2,CUL3,CYC1,DCTN4,DCTN5,DCTN6,DENND1B,DENND5A,DERL2,DYNC1LI1,EIF5A,ERGIC2,ERGIC3,FAM53C,FBXO7,FER,FIP1L1,GET3,GOSR1,GRPEL1,GRPEL2,GSK3A,HGS,HNRNPA1,HNRNPU,HSPA8,HSPA9,IPO11,IPO7,KLHL21,KPNA2,KPNA4,KPNB1,LCP1,LYN,MAGOHB,MAIP1,MED1,MFN2,MTERF4,MTMR2,MYLK2,MYO19,NDEL1,NPLOC4,NSG1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NUP62CL,NXT1,PABPN1,PAK1,PARD3,PCM1,PDCD10,PEF1,PEX14,PHB2,PLEKHA3,PML,PMPCB,POLDIP3,PPM1A,PPP6R1,PTPN11,PTPN23,RAB14,RAB15,RAB18,RAB1A,RAB21,RAB28,RAB35,RAB38,RABGEF1,RABL3,RAE1,RAN,RANGAP1,RBM22,RBM26,RBM27,RBM8A,RBSN,RGPD6,RNF126,RNF31,RNPS1,RPL21,RPL22,RPS7,RUFY3,SAMM50,SAR1A,SARNP,SEC24B,SEC24C,SEC61A2,SEC62,SEC63,SFN,SLBP,SLU7,SMG1,SMG5,SMG7,SMURF1,SNRPB,SNX11,SNX16,SNX5,SOD1,SPCS2,SRP72,SRSF11,SRSF4,SSR1,SSR2,SSR3,STAM,STOML2,STX16,STX18,SUPT6H,TAP2,TBC1D15,TBC1D22B,TCF7L2,THOC1,THOC5,TIMM10,TIMM10B,TIMM44,TIMM50,TMED2,TMED5,TMEM108,TMEM87A,TNPO2,TRAPPC10,TRIM23,TSC1,TTC26,TUBA1C,TUBB,UBB,UBC,UBE2D3,UFD1,UPF3B,UQCRC2,VAMP7,VAPA,VPS26A,VPS35,VPS37A,VPS4A,VPS51,VTI1A,WASH3P,WASH6P,WASHC1,XPO4,ZDHHC18 |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 782 | 133 | ADRM1,AP2B1,ARAF,ATXN3,AUP1,AURKB,AXIN1,BAG2,BAP1,CAPN2,CCNB1,CDC16,CDC27,CDK1,CDK2,CDK5RAP3,CHMP4B,CLPP,CLTA,CLTC,CNOT4,COP1,COPS3,CSNK2A2,CTSL,CUL1,CUL3,CUL4A,DDA1,DDB1,DERL2,DMAC2,DNAJB14,DTL,ECPAS,ERCC8,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,FMR1,GSK3A,HSP90B2P,ITCH,KAT5,MARCHF7,NFE2L2,NPLOC4,NSFL1C,NUDT15,OTUD7B,PCBP2,PCNP,PDCL3,PLAA,PML,POMT2,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,RBBP6,RCHY1,RLIM,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RPS7,SENP1,SIRT1,SMURF1,SNX5,SOCS6,SPOPL,SUMO2,TLK2,TMEM199,TMUB2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,VPS35,VPS37A,VPS4A,WAC,ZFAND2A,ZNRF3 |
| GO_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 938 | 146 | ABHD17B,ADRM1,AP2B1,ARAF,ATM,ATXN3,AUP1,AURKB,AXIN1,AZIN1,BAG2,BAG3,BAP1,CAPN2,CCNB1,CDC16,CDC27,CDK1,CDK2,CDK5RAP3,CHMP4B,CLN6,CLPP,CLTA,CLTC,CNOT4,COP1,COPS3,CSNK2A2,CTSL,CUL1,CUL3,CUL4A,DDA1,DDB1,DERL2,DMAC2,DNAJB14,DTL,ECPAS,EGLN2,ERCC8,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,FMR1,GSK3A,HGS,HSP90B2P,HSPA8,IRAK3,ITCH,KAT5,MARCHF7,MDM4,NFE2L2,NPLOC4,NSFL1C,NUDT15,OAZ3,OTUD7B,PCBP2,PCNP,PDCL3,PLAA,PML,POMT2,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,RBBP6,RCHY1,RHBDD3,RLIM,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RPS7,SENP1,SIRT1,SMURF1,SNX5,SOCS6,SPOPL,SUMO2,TLK2,TMEM199,TMUB2,TRAF2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,VPS35,VPS37A,VPS4A,WAC,ZFAND2A,ZNRF3 |
| GO_MODIFICATION_DEPENDENT_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 642 | 119 | ADRM1,ARAF,ATXN3,AUP1,AURKB,AXIN1,BAP1,CCNB1,CDC16,CDC27,CDK1,CDK2,CNOT4,COP1,COPS3,CSNK2A2,CUL1,CUL3,CUL4A,DDA1,DDB1,DERL2,DMAC2,DNAJB14,DTL,ECPAS,ERCC8,EXOSC10,EXOSC3,EXOSC9,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,GSK3A,HSP90B2P,ITCH,KAT5,NFE2L2,NPLOC4,NSFL1C,OTUD7B,PCBP2,PCNP,PDCL3,PLAA,PML,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,RBBP6,RCHY1,RLIM,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RPS7,SENP1,SIRT1,SMURF1,SPOPL,SUMO2,TLK2,TMUB2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,VPS37A,VPS4A,WAC,ZFAND2A,ZNRF3 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 1930 | 218 | ABHD17B,ACD,AKAP8L,ALYREF,ANP32B,AP1G1,AP2B1,AP3B1,AP4S1,ARCN1,ARL6IP1,ATAD1,ATM,AUP1,AURKB,BAAT,BAG3,BAG4,BAP1,BID,BLZF1,BRCA2,C2CD3,CASC3,CDC40,CDCA5,CDK1,CDK5RAP3,CDT1,CENPA,CENPQ,CEP72,CHMP4B,CLASP2,CLTA,CLTB,CLTC,CPSF2,CSNK2A2,CTDSPL2,DCP1A,DDX1,DERL2,DKC1,DNAJA1,DNAJB6,DNM2,DPP10,DVL3,EIF5A,EXOSC10,EXOSC3,FAM53C,FBXO7,FIP1L1,GET3,GORASP2,GPR158,GRPEL1,GRPEL2,GSK3A,HGS,HNRNPU,HSPA8,HSPA9,ILRUN,IPO11,IPO7,KAT7,KIAA0753,KLHL21,KPNA2,KPNA4,KPNB1,LCP1,LEMD2,LIN7C,LZTFL1,MAGOHB,MAIP1,MAPK8,MCPH1,MED1,MFN2,MIS12,MTBP,MTERF4,NDEL1,NPLOC4,NSFL1C,NSG1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,OTUD7B,PABPN1,PAF1,PAK1,PARD3,PCM1,PDCD10,PES1,PEX14,PHB2,PML,PMPCB,POLDIP3,PPM1A,PPP1R15A,PPP3CC,PPP3R1,PRPF18,PTPN11,RAB11FIP2,RAB14,RAB15,RAB18,RAB1A,RAB21,RAB28,RAB35,RAB38,RAB3GAP1,RABGEF1,RABL3,RAD21,RAE1,RAN,RANGAP1,RBM22,RBM8A,RCC2,RER1,RGPD6,RNF31,RNPS1,RPA2,RPL21,RPL22,RPS7,RUFY3,SAMM50,SAR1A,SARNP,SEC24B,SEC24C,SEC61A2,SEC62,SEC63,SFN,SIX4,SLBP,SLC4A1,SLC7A11,SLF1,SLMAP,SLU7,SMG1,SMG5,SMG7,SMURF1,SNX11,SNX16,SNX5,SPCS2,SRP72,SRSF11,SRSF4,SSR1,SSR2,SSR3,STAM,STX16,STX18,SUPT6H,SUPT7L,TBC1D15,TBC1D22B,TBRG1,TCF7L2,TERF2IP,TFDP2,THOC1,THOC5,TIMM10,TIMM10B,TIMM44,TIMM50,TMED2,TMED5,TNKS,TNPO2,TRIM23,TSC1,TTC26,TTC7B,TWF1,UBB,UBC,UBE2D3,UFD1,UPF3B,UQCRC2,VAMP7,VAPA,VPS26A,VPS35,VPS37A,VPS4A,VTI1A,WAPL,WASH3P,XPO4,ZDHHC18 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 1036 | 150 | AAR2,ABITRAM,ACTR3,ADRM1,AGO2,ANP32B,AP2B1,ATF1,ATM,AXIN1,BAG4,BAIAP2L1,BAZ2A,BIN1,BRF2,BRIX1,CAMSAP1,CD2BP2,CDT1,CELF1,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,CKAP5,CLASP2,CLINT1,CLTA,CLTB,CLTC,COA6,COA8,COPS7B,COX19,COX20,CPSF6,CPSF7,CREB1,CUL4A,DAXX,DDB1,DDX1,DENR,DIAPH3,DMAC2,DMC1,DNAJB14,DR1,DRG1,ECPAS,ECSIT,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4B,EIF5,FER,GRWD1,GTF2H2,GTF3C3,H1-4,H2BC3,H4-16,HAT1,HDGFL3,HJURP,HMGB2,HP1BP3,HSF1,ISY1,KHDC4,LUC7L2,MCM7,MCMDC2,MECP2,MED6,MIS12,MIS18A,MTPN,NAF1,NAP1L1,NAP1L4,NCKAP1,NDEL1,NDUFA10,NDUFA9,NDUFAF6,NDUFS3,NDUFS7,NDUFS8,NSG1,NUDT21,NUP153,NUP205,PAK1,POMP,PPAN,PPM1A,PRPF18,PSMC2,PSMC3,PSMC4,PSMC6,PSMG2,RAD51,RBBP4,RBMX,RICTOR,RNF4,RPA2,SAMM50,SART1,SART3,SENP6,SET,SF1,SF3A2,SF3A3,SLAIN2,SLC25A33,SLU7,SMAD4,SNRPB,SPTY2D1,SRPK1,TBPL2,TMEM170A,TMEM199,TRAF2,TWF1,UBB,UBC,UBE2C,UBE2K,UVRAG,VAMP7,VBP1,VDAC2,WASH3P,WASH6P,WASHC1,XAB2,ZRSR2 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 1267 | 167 | ABITRAM,ABL2,ACD,ACTR3,AKAP8,AKAP8L,ATAD2,ATM,ATMIN,ATXN2L,AURKB,BAG3,BAG4,BAIAP2L1,BAP1,BID,BIN1,BRD4,BUB1,CAMSAP1,CAPN2,CCNB1,CDC25C,CDC27,CDC6,CDCA5,CDKL1,CDT1,CEP120,CEP135,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CLASP2,CLTC,CNOT2,CNOT6,CNOT6L,CNTROB,COA8,CSNK2A2,CUL3,DCP2,DDX11,DKC1,DNM2,DRG1,DYNC1LI1,EDN1,ESPL1,EXOSC10,FBXO7,FER,FMR1,GSK3A,GTF2H2,H1-4,HDGFL3,HNRNPA1,HNRNPU,KAT7,KIF18A,KMT2A,KMT2B,LCP1,LRRTM2,MAP2K7,MAPK8,MCPH1,MECP2,METTL4,MFN2,MIER1,MNS1,MTBP,MTPN,MYO19,NAF1,NCKAP1,NEK2,NEK7,NME6,NSD3,NSFL1C,NSMCE2,NUP62,NUSAP1,PAF1,PAK1,PATL2,PHB2,PHF1,PHIP,PLK4,PML,PPIF,PPP3CC,PPP3R1,PSMG2,RAB3GAP1,RAD1,RAD21,RAE1,RASSF1,RBSN,RCC1,RICTOR,RIF1,RND3,RNF31,RNF4,RNF40,RPS6KA5,SAR1A,SART3,SEC24B,SENP6,SET,SETDB1,SFN,SH2B1,SIRT1,SLAIN2,SLC25A5,SLF1,SMAD4,SMG1,SMG5,SMG7,SMURF1,SNW1,SPTY2D1,STAG1,STAG2,STAM,STX18,SUPT6H,SYT1,TADA2B,TCHP,TERF2IP,TFDP2,TLK2,TNKS,TOP2A,TPX2,TRIP12,TSC1,TWF1,UBE2C,UBE2D3,UBQLN4,USP30,USP7,UVRAG,VDAC1,VPS35,WAPL,WASF2,WASH3P,WASH6P,WASHC1,ZEB2,ZNF335 |
| GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 482 | 100 | ATM,AURKB,BABAM1,BID,BRD4,BUB1,CCNB1,CDC16,CDC25A,CDC25C,CDC27,CDC6,CDCA5,CDK1,CDK2,CDK5RAP3,CDT1,CEP135,CEP57,CEP72,CEP76,CHEK1,CKAP5,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL1,CUL3,CUL4A,DDB1,DTL,DYNC1LI1,ESPL1,FBXO7,FGFR1OP,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HMMR,HUS1B,KLF4,KLHL18,LSM11,MDM4,MECP2,MTA3,MTBP,NAE1,NEK2,NSMCE2,ODF2,PAF1,PCM1,PHB2,PLK4,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RAD21,RCC2,RFWD3,RNASEH2B,RPA2,SFN,SYF2,TFDP2,TOPBP1,TPX2,TUBB,UBE2C,UIMC1,USP47,VPS4A,WEE1,ZNF16 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1301 | 168 | ABHD17B,ACER1,ADRM1,AMT,AP2B1,ARAF,ATM,ATXN3,AUP1,AURKB,AXIN1,AZIN1,BAG2,BAG3,BAP1,BCAN,CAPN2,CCNB1,CDADC1,CDC16,CDC27,CDK1,CDK2,CDK5RAP3,CHMP4B,CLN6,CLPP,CLTA,CLTC,CNOT4,COP1,COPS3,CSNK2A2,CTSL,CUL1,CUL3,CUL4A,DDA1,DDB1,DERL2,DMAC2,DNAJB14,DTL,ECPAS,EGLN2,ERAP1,ERCC8,FAF1,FBXL3,FBXO11,FBXO2,FBXO6,FBXO7,FBXW11,FMR1,GALC,GDPD3,GLA,GLUD1,GSK3A,HGS,HINT1,HMMR,HSD17B10,HSP90B2P,HSPA8,IRAK3,ITCH,KAT5,LIPC,LVRN,MARCHF7,MBD4,MDM4,NFE2L2,NPEPPSP1,NPLOC4,NSFL1C,NT5C3A,NUDT15,NUDT4,OAZ3,OTUD7B,PCBP2,PCNP,PDCL3,PDXDC1,PLAA,PML,PNPLA8,POMT2,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,RBBP6,RCHY1,RHBDD3,RLIM,RNF126,RNF19B,RNF4,RNF40,RNF6,RNF7,RPS7,SENP1,SIRT1,SMURF1,SNX5,SOCS6,SPOPL,SUMO2,TET3,TLK2,TMEM199,TMUB2,TRAF2,TRIP12,UBA6,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBE2Z,UBE3A,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,UNG,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,VPS35,VPS37A,VPS4A,WAC,ZFAND2A,ZNRF3 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1673 | 194 | AATF,ACD,AGO2,ATAD2,ATF2,ATF4,ATXN1L,AURKB,BAG3,BANK1,BAP1,BAZ2A,BCL7A,BRCA2,BRMS1,BRMS1L,C11orf95,C1D,CDC6,CDK2,CELF1,CHCHD3,CIR1,CLTC,CNOT10,CNOT2,CNOT3,CNOT6L,CNOT9,COA8,COPS2,CPEB1,CREB1,CREBBP,CREBZF,CTBP2,CUL3,DAXX,DCAF1,DCP2,DDX54,DEPDC1,DNAJB1,DNAJB6,DNAJC2,DOT1L,DPF2,DR1,E2F3,E4F1,EDN1,EIF3E,EXOSC10,EZH1,FAM172BP,FBXW11,FMR1,FOXC1,FOXK2,FXR1,GLA,GSK3A,H1-4,H4-16,HAT1,HIC1,HINFP,HMGB2,HNRNPA1,HNRNPU,HSF1,HSPA8,IGHMBP2,ILF3,KAT5,KAT7,KDM2A,KLF4,KMT5A,LANCL2,LRRFIP1,MAF1,MCPH1,MDM4,MECP2,MED1,MIER1,MIER3,MSL3,MTA3,MXD1,N4BP2L2,NAB1,NCOR1,NELFA,NFKB1,NKAP,NMI,NONO,NOTCH1,NSD2,OTUD7B,PAF1,PATL2,PAWR,PER3,PEX14,PFDN5,PGGT1B,PHB2,PML,PPM1A,PUM1,PUS7,RBBP8,RBM10,RC3H1,RCOR3,REL,RFC1,RIF1,RLIM,RPS6KA5,SARNP,SCAF4,SCAF8,SCAI,SET,SETDB1,SF1,SIK1,SIN3B,SIRT1,SIX4,SMAD4,SNW1,SOD1,SOX15,SP3,SPINDOC,STRN3,TAF9B,TBPL2,TBR1,TBX3,TCERG1,TCF3,TCF7L2,TDP2,TFDP2,THAP1,TSC1,UBB,UBC,UBE2D3,UBE2I,UIMC1,USP3,USP47,WAPL,YAF2,YAP1,YTHDF2,YTHDF3,YY1,ZBTB14,ZBTB2,ZBTB26,ZBTB33,ZBTB34,ZEB1,ZEB2,ZNF131,ZNF136,ZNF140,ZNF148,ZNF157,ZNF165,ZNF189,ZNF202,ZNF215,ZNF24,ZNF263,ZNF296,ZNF382,ZNF568,ZNF597,ZNF613,ZNF639,ZNF649,ZNF668,ZNF675,ZNF835,ZNF85 |
| GO_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 271 | 75 | AKAP8,AKAP8L,ATM,AURKB,BABAM1,BRD4,CCNA2,CCNB1,CCNB2,CDC25A,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CEP135,CEP57,CEP72,CEP76,CHEK1,CKAP5,CUL1,DNM2,DTL,FBXL3,FBXW11,FGFR1OP,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HMMR,HUS1B,MASTL,MECP2,MELK,MTA3,NAE1,NEK2,ODF2,PCM1,PLK4,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAD21,RCC2,RNASEH2B,SYF2,TAF2,TOPBP1,TPX2,TUBB,UIMC1,USP47,VPS4A,WEE1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 637 | 112 | ATF2,ATM,AURKB,BABAM1,BIN1,BUB1,CASP3,CCNB1,CCNK,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CUL1,CUL4A,DOT1L,DTL,DYNC1LI1,E4F1,EIF4G2,ESPL1,FBXO6,FBXO7,FEM1B,FOXC1,HINFP,HUS1B,INTS7,IPO7,KLF4,L3MBTL2,MCPH1,MDM4,MTBP,MUS81,NAE1,NEK2,NME6,NOTCH1,PEA15,PHC3,PML,PPM1A,PPP1R15A,PRCC,PRKAB1,PRR11,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,PTPN11,RAD1,RAD21,RAD51,RASSF1,RBBP4,RBBP8,RFWD3,RNASEH2B,RPA2,RPA4,SDE2,SFN,SLC25A33,SLC38A9,SYF2,TBRG1,TCF7L2,TFDP2,THAP5,THOC1,THOC5,TNKS,TOP2A,TOPBP1,UHRF2,UIMC1,USP47,VPS4A,WAC,WAPL,WEE1,YAF2,ZBTB49 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 1151 | 152 | ACD,AKAP8L,ALYREF,ANP32B,AP1G1,AP2B1,AP3B1,AP4S1,ARCN1,ARL6IP1,AUP1,BAAT,BAG3,BAG4,BAP1,BID,CASC3,CDC40,CHMP4B,CLTA,CLTB,CLTC,CPSF2,CSNK2A2,CTDSPL2,DERL2,EIF5A,FAM53C,FBXO7,FIP1L1,GET3,GRPEL1,GRPEL2,GSK3A,HGS,HNRNPU,HSPA8,HSPA9,IPO11,IPO7,KPNA2,KPNA4,KPNB1,LCP1,MAGOHB,MAIP1,MED1,MFN2,MTERF4,NDEL1,NPLOC4,NSG1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,PAK1,PARD3,PCM1,PDCD10,PEX14,PHB2,PML,PMPCB,POLDIP3,PPM1A,PTPN11,RAB14,RAB15,RAB18,RAB1A,RAB21,RAB28,RAB35,RAB38,RABGEF1,RABL3,RAE1,RAN,RANGAP1,RBM22,RBM8A,RGPD6,RNF31,RNPS1,RPL21,RPL22,RPS7,RUFY3,SAMM50,SAR1A,SARNP,SEC24B,SEC24C,SEC61A2,SEC62,SEC63,SFN,SLBP,SLU7,SMG1,SMG5,SMG7,SMURF1,SNX11,SNX16,SNX5,SPCS2,SRP72,SRSF11,SRSF4,SSR1,SSR2,SSR3,STAM,STX16,STX18,SUPT6H,TBC1D15,TBC1D22B,TCF7L2,THOC1,THOC5,TIMM10,TIMM10B,TIMM44,TIMM50,TMED2,TMED5,TNPO2,TRIM23,TSC1,TTC26,UBB,UBC,UBE2D3,UFD1,UPF3B,UQCRC2,VAMP7,VPS26A,VPS35,VPS37A,VPS4A,VTI1A,WASH3P,XPO4,ZDHHC18 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1930 | 1559 | 181 | AIDA,AP1G1,ATF4,ATM,ATXN3,AXIN1,BABAM1,BAG1,BAG2,BAG3,BAG4,BAP1,BCL2L12,BID,BRD4,BTK,CACTIN,CAMK2G,CD200R1,CD226,CGAS,CHEK1,CHORDC1,CLASP2,CLDN4,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,CUL4A,DAXX,DDX11,DDX60,DERL2,DNAJA1,DNAJB1,DNAJB6,DNAJC2,DNAJC7,DVL3,EDN1,EEF1E1,EID3,ERAP1,ERCC8,FBXO7,FBXW11,FEM1B,FMR1,FXR1,GPATCH3,HELB,HIC1,HMGB2,HNRNPK,HSF1,HSPA8,HSPH1,IL18RAP,ILRUN,IRAK3,ITCH,KLF4,KMT5A,LYN,MAP2K7,MAP4K4,MARCHF7,MATR3,MCPH1,MED1,MICB,MUC13,NCOR1,NDEL1,NFE2L2,NFKB1,NMI,NONO,NPLOC4,NSD2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OTUD4,OXR1,PAK1,PAK2,PARP14,PAWR,PCBP2,PDCD10,PML,POLR3C,POLR3F,PPP1R15A,PPP4C,PPP4R2,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RAD51,RAD51AP1,RAE1,RFWD3,RHBDD3,RICTOR,RIF1,RIOK3,RNASEH2B,RPA2,RPS6KA5,SERPINC1,SHLD1,SHLD2,SIRT1,SLC7A11,SLF1,SMG1,SOD1,SOX15,SPINK5,SUCNR1,TAB2,TAF9B,TERF2IP,TFIP11,THBD,THOC1,THOC5,TICAM1,TNIP2,TRAF2,TRAF4,TRIP12,TSC1,TYRO3,UBB,UBC,UBE2D3,UBE2K,UBQLN4,UFD1,UIMC1,USP1,USP14,USP47,VAMP7,VPS35,XIAP,YJU2,YTHDF2,YTHDF3,ZEB2,ZNF622,ZNF675 |
| GO_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 324 | 78 | ABRAXAS2,ACTR3,AKAP8,AKAP8L,ATM,AURKB,BUB1,CCNB1,CCNB1IP1,CDC27,CDC6,CDCA5,CDT1,CENPK,CENPQ,CENPT,CENPW,CHMP4B,CHMP5,CIAO2A,CSNK2A2,CUL3,DDX11,DMC1,DYNC1LI1,ESPL1,FANCM,HJURP,HNRNPU,INCENP,KIF18A,KIF2C,KNSTRN,KPNB1,MCMDC2,MIS12,MIS18A,MSH4,MUS81,NCAPH,NCAPH2,NDEL1,NEK2,NSMCE2,NUF2,NUP43,NUP62,NUSAP1,PHB2,PHF13,PMF1,PRC1,PSMG2,PUM1,PUM2,RACGAP1,RAD18,RAD21,RAN,RCC1,RCC2,RIOK3,SLC25A5,SLF1,SMC1B,SMC4,SRPK1,STAG1,STAG2,TENT4A,TLK2,TNKS,TOP2A,TOP3A,UBE2I,UVRAG,VPS4A,WAPL |
| GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 214 | 64 | ATM,AURKB,BABAM1,BRD4,CCNB1,CDC25A,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CEP135,CEP57,CEP72,CEP76,CHEK1,CKAP5,CUL1,DTL,FGFR1OP,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HMMR,HUS1B,MECP2,MTA3,NAE1,NEK2,ODF2,PCM1,PLK4,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAD21,RCC2,RNASEH2B,SYF2,TOPBP1,TPX2,TUBB,UIMC1,USP47,VPS4A |
| GO_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 795 | 121 | ACTL6A,ACTR6,ACTR8,AKAP8,AKAP8L,ANP32B,ANP32E,ATAD2,ATF2,ATM,AURKB,BABAM1,BAP1,BAZ2A,BRCA2,BRD1,BRD4,BRMS1,BRMS1L,CCNA2,CCNB1,CDK1,CDK2,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,CHEK1,CREBBP,DAXX,DCAF1,DDB1,DDX11,DNAJC2,DOT1L,DPF2,DR1,EZH1,FAM172BP,FMR1,GRWD1,H1-4,H2BC3,H4-16,HAT1,HJURP,HMGB2,HNRNPU,HP1BP3,ING3,INO80B,JMJD6,KANSL1,KANSL2,KAT5,KAT7,KDM2A,KDM6A,KDM6B,KMT2A,KMT2B,KMT5A,L3MBTL2,MAPK8,MBIP,MECP2,METTL4,MIER1,MIS18A,MSL2,MSL3,MTA3,NAP1L1,NAP1L4,NCOR1,NSD2,NSD3,NUCKS1,PAF1,PAK1,PCGF5,PHF1,PHF13,PRDM4,PWP1,RBBP4,RIF1,RNF40,RPS6KA5,SART3,SET,SETDB1,SIN3B,SIRT1,SMAD4,SNW1,SOX15,SPTY2D1,SRPK1,SUPT6H,SUPT7L,SUPV3L1,TADA1,TADA2B,TAF5L,TAF9B,TET3,TLK2,TRIP12,UBE2A,UIMC1,USP16,USP21,USP3,USP7,WAC,ZNF335 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1280 | 158 | ATAD2,ATF2,ATXN1L,AURKB,BAG3,BAP1,BAZ2A,BCL7A,BRMS1,BRMS1L,C11orf95,C1D,CDK2,CHCHD3,CIR1,CNOT2,COPS2,CREB1,CREBBP,CREBZF,CTBP2,CUL3,DAXX,DCAF1,DDX54,DEPDC1,DNAJB1,DNAJB6,DOT1L,DPF2,DR1,E2F3,E4F1,EDN1,EZH1,FAM172BP,FBXW11,FOXC1,FOXK2,H1-4,H4-16,HAT1,HIC1,HINFP,HMGB2,HNRNPU,HSF1,HSPA8,IGHMBP2,ILF3,KAT5,KAT7,KDM2A,KLF4,KMT5A,LANCL2,LRRFIP1,MAF1,MCPH1,MDM4,MECP2,MED1,MIER1,MIER3,MSL3,MTA3,MXD1,N4BP2L2,NAB1,NCOR1,NELFA,NFKB1,NKAP,NONO,NOTCH1,NSD2,OTUD7B,PAF1,PAWR,PER3,PEX14,PFDN5,PHB2,PML,PPM1A,RBBP8,RBM10,RCOR3,REL,RFC1,RIF1,RLIM,RPS6KA5,SARNP,SCAF4,SCAF8,SCAI,SET,SETDB1,SF1,SIN3B,SIRT1,SIX4,SMAD4,SNW1,SOX15,SP3,SPINDOC,STRN3,TAF9B,TBPL2,TBR1,TBX3,TCERG1,TCF3,TCF7L2,TDP2,TFDP2,THAP1,UBB,UBC,UBE2D3,UBE2I,UIMC1,USP3,USP47,YAF2,YAP1,YY1,ZBTB14,ZBTB2,ZBTB26,ZBTB33,ZBTB34,ZEB1,ZEB2,ZNF131,ZNF136,ZNF140,ZNF148,ZNF157,ZNF165,ZNF189,ZNF202,ZNF215,ZNF24,ZNF263,ZNF296,ZNF382,ZNF568,ZNF597,ZNF613,ZNF639,ZNF649,ZNF668,ZNF675,ZNF835,ZNF85 |
| GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 478 | 92 | ARAF,ATXN3,AUP1,AURKB,BAG2,CCNB1,CDC16,CDC27,CDK1,CDK2,COP1,CUL1,CUL3,CUL4A,DDA1,DDB1,DERL2,DMAC2,DNAJB14,ECPAS,ERCC8,FAF1,FBXL3,FBXO2,FBXO6,FBXW11,FMR1,GSK3A,HSP90B2P,ITCH,KAT5,MARCHF7,NFE2L2,NPLOC4,NSFL1C,NUDT15,PCBP2,PCNP,PLAA,PML,POMT2,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RCHY1,RNF126,RNF19B,RNF4,RNF40,RNF7,SENP1,SIRT1,SMURF1,SOCS6,SPOPL,SUMO2,TLK2,TMUB2,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2I,UBE2K,UBQLN4,UBXN11,UBXN4,UBXN8,UFD1,UFL1,USP14,USP7,WAC,ZFAND2A |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 987 | 135 | AADAC,ABL2,AGO2,ARAF,ATM,ATP6V0A2,ATP6V1G1,ATP6V1H,ATXN3,AXIN1,AZIN1,BAG2,BAG3,CASP3,CDK5RAP3,CHMP4B,CISD2,CNOT6L,COP1,CRTC3,CSNK2A2,DCP1A,DCP2,DDA1,DDB1,DERL2,DHX34,DIS3,DKC1,DTL,EGLN2,EIF4G2,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FAF1,FBXO7,FMR1,FOXK2,FXR1,GRSF1,GSK3A,HGS,HNRNPU,HSF1,HSPA8,IRAK3,ITCH,KAT5,MAPK8,MARCHF7,MDM4,MFN2,MTMR2,NAF1,NFE2L2,NUDT15,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OAZ3,PABPC1,PAIP1,PDCL3,PFKFB3,PML,PRKAB1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB3GAP1,RAE1,RBM10,RC3H1,RCHY1,RHBDD3,RNF19B,RNF40,RPS7,SENP1,SET,SIRT1,SLC11A1,SLC38A9,SMURF1,SNX5,SUMO2,SUPV3L1,TAB2,TENT4A,TICAM1,TLK2,TSC1,UBB,UBC,UBE2K,UBE3A,UBQLN4,UFL1,USP14,USP30,USP7,UVRAG,VDAC1,VPS26A,VPS35,WAC,WASHC1,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZFAND2A |
| GO_RNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 404 | 84 | AGO2,ATM,CASC3,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CSDE1,DCP1A,DCP2,DHX34,DIS3,DKC1,EIF3E,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FMR1,FXR1,GRSF1,GSPT1,HNRNPU,HSPA8,MAGOHB,MTPAP,NAF1,NT5C3B,PABPC1,PAIP1,PATL2,PRPF18,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RBM10,RBM7,RBM8A,RC3H1,RNASEH2A,RNASEH2B,RNPS1,RPL21,RPL22,RPS7,SET,SLC11A1,SMG1,SMG5,SMG7,SMG8,SMG9,SUPV3L1,TENT4A,UBB,UBC,UPF3B,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZCCHC8 |
| GO_CELL_DIVISION | 0.0e+00 | 0.0e+00 | 1930 | 598 | 102 | ABRAXAS2,ACTR3,ACTR8,ANKLE2,AURKB,BABAM1,BRCA2,BUB1,CCNA2,CCNB1,CCNB2,CCNK,CCNT1,CCNT2,CDC16,CDC25A,CDC25C,CDC6,CDCA5,CDK1,CDK2,CDT1,CENPA,CENPT,CENPW,CEP55,CHMP4B,CHMP5,CKAP2,CKAP5,CLASP2,CLTA,CLTC,CNTROB,CSPP1,CUL3,CUZD1,DYNC1LI1,E4F1,ESPL1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HNRNPU,INCENP,JTB,KIF2C,KLHL21,KMT5A,KNSTRN,MASTL,MIS12,MIS18A,MYO19,NCAPH,NEK2,NOTCH1,NSMCE2,NUF2,NUP43,NUP62,NUSAP1,ORC6,PARD3,PHF13,PLK4,PMF1,PRC1,RAB35,RACGAP1,RAD21,RAE1,RAN,RBBP8,RCC1,RCC2,SDE2,SENP5,SFN,SMC4,SPART,STAG1,STAG2,TIAL1,TNKS,TOP2A,TPX2,TUBA1C,TUBB,UBE2C,UBE2I,USP16,UVRAG,VPS4A,WAPL,WEE1,WNT9B,ZC3HC1,ZNF16 |
| GO_CELLULAR_NITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 587 | 101 | AGO2,ATM,CASC3,CASP3,CDADC1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CSDE1,DCP1A,DCP2,DFFB,DHX34,DIS3,DKC1,EIF3E,ENTPD7,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FMR1,FXR1,GRSF1,GSK3A,GSPT1,HINT1,HMGB2,HNRNPU,HSF1,HSPA8,KPNB1,MAGOHB,MBD4,MTPAP,MUS81,NAF1,NT5C3A,NT5C3B,NUDT15,NUDT4,PABPC1,PAIP1,PATL2,PRPF18,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RBM10,RBM7,RBM8A,RC3H1,RNASEH2A,RNASEH2B,RNPS1,RPL21,RPL22,RPS7,SET,SLC11A1,SMG1,SMG5,SMG7,SMG8,SMG9,SUPV3L1,TENT4A,TET3,UBB,UBC,UNG,UPF3B,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZCCHC8 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL | 0.0e+00 | 0.0e+00 | 1930 | 299 | 72 | ABRAXAS2,ACTL6A,ACTR8,ADRM1,ATXN3,BABAM1,BAP1,CCNA2,CDC25A,CDK1,COPS2,COPS3,COPS7B,DESI2,EIF3F,FOXK2,HGS,INO80B,INO80D,ITCH,MDM4,MINDY4,OTUD4,OTUD7B,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RCE1,SART3,SENP1,SENP5,SENP6,SENP7,SMAD4,STAM,TADA2B,TAF9B,TNIP2,TRAF2,UBB,UBC,UFD1,UIMC1,USP1,USP14,USP16,USP21,USP3,USP30,USP38,USP47,USP7,USPL1,WDR20,WDR48,YY1 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 831 | 118 | AADAC,ABL2,AGO2,ARAF,ATM,ATP6V0A2,ATP6V1G1,ATP6V1H,ATXN3,AXIN1,BAG2,BAG3,CASP3,CDK5RAP3,CHMP4B,CISD2,CNOT6L,COP1,CSNK2A2,DCP1A,DCP2,DDA1,DERL2,DHX34,DIS3,DKC1,EIF4G2,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FAF1,FBXO7,FMR1,FOXK2,FXR1,GRSF1,GSK3A,HNRNPU,HSF1,HSPA8,ITCH,KAT5,MAPK8,MARCHF7,MFN2,MTMR2,NAF1,NFE2L2,NUDT15,PABPC1,PAIP1,PDCL3,PFKFB3,PML,PRKAB1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB3GAP1,RBM10,RC3H1,RCHY1,RNF19B,RNF40,RPS7,SENP1,SET,SIRT1,SLC11A1,SLC38A9,SMURF1,SNX5,SUMO2,SUPV3L1,TAB2,TENT4A,TICAM1,TLK2,TSC1,UBB,UBC,UBE2K,UBE3A,UBQLN4,UFL1,USP14,USP30,USP7,UVRAG,VDAC1,VPS26A,VPS35,WAC,WASHC1,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZFAND2A |
| GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 636 | 102 | AGO2,ATM,CASC3,CASP3,CDADC1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CSDE1,DCP1A,DCP2,DFFB,DHX34,DIS3,DKC1,EIF3E,ENTPD7,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FMR1,FXR1,GRSF1,GSK3A,GSPT1,HINT1,HMGB2,HNRNPU,HSF1,HSPA8,KPNB1,MAGOHB,MBD4,MTPAP,MUS81,NAF1,NFE2L2,NT5C3A,NT5C3B,NUDT15,NUDT4,PABPC1,PAIP1,PATL2,PRPF18,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RBM10,RBM7,RBM8A,RC3H1,RNASEH2A,RNASEH2B,RNPS1,RPL21,RPL22,RPS7,SET,SLC11A1,SMG1,SMG5,SMG7,SMG8,SMG9,SUPV3L1,TENT4A,TET3,UBB,UBC,UNG,UPF3B,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1,ZCCHC8 |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 0.0e+00 | 1930 | 940 | 126 | ALYREF,AP1G1,AP2B1,ATP6V1H,AZI2,BIN1,BRD4,BUB1,CBLL1,CCDC86,CCNA2,CCNK,CCNT1,CCNT2,CD200R1,CDC25C,CDK1,CENPA,CGAS,CHMP4B,CHMP5,COPS7B,CREB1,CREBBP,CRTC3,CTBP2,CUL1,CUL4A,DAXX,DCAF1,DDB1,DDX11,DENR,DOCK2,DYNC1LI1,E4F1,EIF3F,EIF3G,EIF3L,EIF4A1,FMR1,GTF2F1,HMGN2,HNRNPA1,HNRNPK,HSPA8,ILF3,IPO7,ITCH,ITSN2,KAT5,KIN,KPNA2,KPNA4,KPNB1,LYN,LYZ,MECP2,MICB,NCKAP1,NELFA,NFE2L2,NOTCH1,NUCKS1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PABPC1,PABPN1,PAK2,PCBP2,PDCL3,PML,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC3,RAB1A,RAE1,RAN,RBM15,RCC1,RICTOR,RPL21,RPL22,RPS7,SET,SETDB1,SF3B2,SIRT1,SLC25A5,SLC52A2,SNW1,SRPK1,SUPT6H,TAP2,THOC1,THOC5,TICAM1,TOP2A,TRIM23,TYRO3,UBB,UBC,UBE2I,UBE3A,UNG,USP7,UVRAG,VAPA,VDAC1,VPS35,VPS37A,VPS4A,WAPL,WASF2,WDR48,XRCC4,ZC3HAV1,ZNF639 |
| GO_ORGANELLE_FISSION | 0.0e+00 | 0.0e+00 | 1930 | 450 | 84 | ABRAXAS2,ACTR3,AKAP8,AKAP8L,ATM,AURKB,BRCA2,BUB1,CCNB1,CCNB1IP1,CDC25C,CDC27,CDC6,CDCA5,CDT1,CENPK,CHEK1,CHMP4B,CHMP5,CLASP2,CUL3,DMC1,DNM2,DRG1,DYNC1LI1,EDN1,ESPL1,FANCM,HNRNPU,HSF1,INCENP,KIF18A,KIF2C,KLHDC3,KNSTRN,KPNB1,MASTL,MCMDC2,MIS12,MND1,MSH4,MTBP,MTFR2,MUS81,MYO19,NCAPH,NCAPH2,NDEL1,NEK2,NME6,NSFL1C,NSMCE2,NUF2,NUP62,NUSAP1,PHB2,PHF13,PHIP,PRC1,PSMC3IP,PSMG2,RACGAP1,RAD1,RAD21,RAD51,RAD54L,RAN,RCC1,SH2B1,SLF1,SMC4,SPDYA,STAG1,STAG2,TENT4A,TNKS,TOP2A,TPX2,UBB,UBE2C,USP16,VPS35,VPS4A,WAPL |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 1235 | 146 | ACER1,AIPL1,ATF2,ATF4,ATM,ATP6V0A2,ATP6V1G1,ATXN3,AURKB,BABAM1,BAG1,BAG2,BAG3,BAG4,BRCA2,BRD1,CAMK2G,CAPN2,CASP3,CCNA2,CCNB1,CDC25A,CHEK1,CHORDC1,COP1,COPS3,CPEB1,CREB1,CREBBP,DAXX,DDB1,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC2,DNAJC7,DNM2,DTL,EDN1,EGLN2,EIF2B4,ELK1,ERCC8,FANCG,FBXL3,FMR1,GNB1,GRK7,GTF2H2,HP1BP3,HSF1,HSF2,HSP90AA2P,HSP90AA4P,HSP90AB4P,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,INIP,INTS7,KAT5,LYN,LZIC,MAP2K7,MAPK8,MBD4,MBIP,MDM4,MECP2,MICB,MTPN,NFE2L2,NFKB1,NOTCH1,NUCKS1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PAK1,PDCL3,PER3,PHB2,PML,POLK,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,RAD1,RAD18,RAD51,RAD51AP1,RAD54L,RAE1,RBM4B,RFWD3,RO60,RPA2,RRH,RRM1,SDE2,SIK1,SIRT1,SLC7A11,SLU7,SMAD4,SOD1,SORD,THBD,TLK2,TMEM199,TNFRSF10A,TOPBP1,TSC1,UBB,UBC,UBE2A,UCP3,UIMC1,USP1,USP47,XRCC4,YAP1,YY1 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1930 | 419 | 80 | AAR2,AATF,AGO2,ATM,BRIX1,C1D,CD2BP2,CELF1,CPSF6,CPSF7,CUL4A,DDX1,DDX52,DDX54,DENR,DIS3,DKC1,EIF2A,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF5,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FCF1,FRG1,GAR1,ISY1,KHDC4,LTO1,LUC7L2,MRM3,MRPS2,MTERF4,NAF1,NIP7,NOL9,NSA2,NSUN3,NUDT21,PAK1IP1,PES1,POP7,PPAN,PRPF18,PWP1,RAN,RBMX,RIOK3,RPS7,RRP1,RRP9,SART1,SART3,SBDS,SF1,SF3A2,SF3A3,SLU7,SNRPB,SRFBP1,SRPK1,TEX10,THUMPD1,TSC1,TSR1,TSR2,URB2,UTP18,WBP11,XAB2,ZCCHC4,ZNF622,ZRSR2 |
| GO_DNA_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1930 | 288 | 66 | ACTL6A,ACTR8,ALYREF,AP5Z1,ATM,BRCA2,CCNB1IP1,CGAS,CHEK1,CLCF1,DCAF1,DMC1,EID3,EXOSC3,FANCM,GINS4,H1-4,HELB,HMGB2,HUS1B,IGHMBP2,INO80B,INO80D,KIN,KLHDC3,KPNA2,MCM7,MCMDC2,MMS22L,MND1,MSH4,MUS81,NONO,NSD2,NSMCE2,NUCKS1,POLL,PPP4C,PPP4R2,PSMC3IP,RAD21,RAD51,RAD51AP1,RAD54L,RBBP8,RECQL,RECQL4,RFWD3,RIF1,RNF138,RPA2,RPA4,SHLD1,SHLD2,SUPT6H,SUPV3L1,TCF3,TERF2IP,THOC1,TOP2A,UBQLN4,UNG,WDR48,XRCC4,YY1,ZSCAN4 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 356 | 73 | ATM,AURKB,BABAM1,BUB1,CCNB1,CCNK,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL1,DTL,DYNC1LI1,ESPL1,FBXO7,HUS1B,KLF4,L3MBTL2,MDM4,MTBP,NAE1,NEK2,NME6,PHC3,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RAD1,RAD21,RAD51,RBBP4,RBBP8,RFWD3,RPA2,SFN,SYF2,TFDP2,TNKS,TOPBP1,UIMC1,USP47,VPS4A,WAPL,WEE1,YAF2 |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 1930 | 944 | 122 | ABHD17B,ACD,AP2B1,AP3B1,ATAD1,ATM,AURKB,BAAT,BAG3,BAG4,BAP1,BID,BRCA2,C2CD3,CDCA5,CDK1,CDK5RAP3,CDT1,CENPA,CENPQ,CEP72,CHMP4B,CSNK2A2,DCP1A,DDX1,DKC1,DNAJA1,DNAJB6,DNM2,FAM53C,FBXO7,GET3,GRPEL1,GRPEL2,GSK3A,HGS,HNRNPU,HSPA8,ILRUN,IPO11,IPO7,KAT7,KIAA0753,KLHL21,KPNA2,KPNA4,KPNB1,LEMD2,LZTFL1,MAIP1,MAPK8,MCPH1,MED1,MFN2,MIS12,MTBP,MTERF4,NSFL1C,NUP153,NUP50,NUP62,NXT1,OTUD7B,PAF1,PCM1,PES1,PEX14,PHB2,PML,PMPCB,PPP1R15A,PPP3CC,PPP3R1,RAB35,RAB3GAP1,RAD21,RAN,RANGAP1,RBM22,RCC2,RER1,RGPD6,RNF31,RPA2,RPL21,RPL22,RPS7,SAMM50,SEC61A2,SEC62,SEC63,SFN,SIX4,SLF1,SMURF1,SNX16,SPCS2,SRP72,SSR3,SUPT7L,TBRG1,TERF2IP,TFDP2,TIMM10,TIMM10B,TIMM44,TIMM50,TNKS,TNPO2,TTC26,UBB,UBC,UBE2D3,UQCRC2,VAMP7,VAPA,VPS35,VPS37A,VPS4A,VTI1A,WAPL,WASH3P |
| GO_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 347 | 71 | ACD,AKAP8,AKAP8L,ATAD2,ATM,AURKB,BRD4,BUB1,CCNB1,CDC27,CDC6,CDCA5,CDT1,CHEK1,CUL3,DCP2,DDX11,DKC1,DYNC1LI1,ESPL1,EXOSC10,FMR1,GTF2H2,H1-4,HNRNPA1,HNRNPU,KAT7,KMT2A,KMT2B,MAP2K7,MAPK8,MCPH1,MECP2,METTL4,MIER1,NAF1,NEK2,NEK7,NSD3,NSMCE2,PAF1,PHF1,PML,PSMG2,RAD21,RIF1,RNF4,RNF40,RPS6KA5,SART3,SENP6,SET,SETDB1,SIRT1,SLF1,SMAD4,SMG1,SMG5,SMG7,SNW1,SPTY2D1,SUPT6H,TADA2B,TERF2IP,TLK2,TNKS,TOP2A,TRIP12,USP7,WAPL,ZNF335 |
| GO_REGULATION_OF_MRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 141 | 46 | C9orf78,CCNB1,CCNT1,CDK11A,CELF1,CPEB1,CPSF6,CPSF7,CWC22,DAZAP1,FMR1,FXR1,HNRNPA1,HNRNPK,HNRNPL,HNRNPU,HSF1,JMJD6,NSRP1,NUDT21,PABPN1,PAF1,PAPOLA,RBM10,RBM15,RBM17,RBM25,RBM42,RBM4B,RBM7,RBM8A,RBMX,RNF40,RNPS1,SART3,SLTM,SMU1,SNRPA,SNW1,SREK1,SRPK1,SRSF4,SUPT6H,VIRMA,ZC3H14,ZC3H3 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1930 | 1258 | 141 | ABL2,ACTL6A,AIPL1,ALG5,ARAF,ATF2,ATM,AURKB,AXIN1,BAG4,BANK1,BRCA2,BRD1,BRD4,BTK,CCNB1,CDK1,CDK2,CHEK1,CLCF1,CLK1,CLK3,CNOT9,CREBBP,CSNK1G1,CSNK2A2,CWC27,DCAF1,DOT1L,DPF2,DPH2,DPH5,DPH7,DR1,DYRK2,EEF1AKMT2,EGLN2,EZH1,FBXO11,FER,FGFR1OP,GGNBP2,GSK3A,H1-4,HAT1,HIPK1,HSF1,IBTK,ING3,JMJD6,KANSL1,KANSL2,KAT5,KAT7,KDM6A,KMT2A,KMT2B,KMT5A,LYN,MAP2K7,MAPK8,MASTL,MBIP,MECP2,MELK,METTL21A,MSL2,MSL3,MYLK2,NAA20,NAA25,NAA35,NSD2,NSD3,NSMCE2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OGFOD1,OXR1,PAK1,PAK2,PARD3,PARP14,PARP2,PDCD10,PDCL3,PHF1,PPIF,PPIG,PPIL4,PPP2R5D,PPWD1,PRDM4,PTPN11,PWP1,RAE1,RANGAP1,RAP2C,RICTOR,RIF1,RPS6KA5,SCYL1,SENP1,SENP5,SENP6,SENP7,SET,SETD4,SETDB1,SIRT1,SMAD4,SMG1,SNW1,STT3A,SUMO2,SUMO3,SUPT6H,SUPT7L,TADA1,TADA2B,TAF5L,TAF9B,TERF2IP,TET3,TLK2,TNKS,TTLL4,TWF1,TYRO3,UBA2,UBE2I,UBE2K,USPL1,WEE1,YES1,ZDHHC18,ZNF335 |
| GO_RNA_3_END_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 150 | 47 | ALYREF,CASC3,CCNB1,CCNT1,CDC40,CPEB1,CPSF2,CPSF6,CPSF7,DKC1,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FIP1L1,GRSF1,HSD17B10,HSF1,INTS7,LSM11,MAGOHB,MTPAP,NUDT21,PABPC1,PABPN1,PAF1,PAPOLA,POLDIP3,RBM8A,RNF40,RNPS1,SARNP,SCAF8,SLBP,SLU7,SNRPA,SRSF11,SRSF4,SUPV3L1,TENT4A,THOC1,THOC5,UPF3B,VIRMA,ZC3H14,ZC3H3 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 624 | 94 | ACD,ACTR3,AKAP8,AKAP8L,ATM,ATMIN,AURKB,BAG4,BAIAP2L1,BAP1,BID,BIN1,BRD4,CCNB1,CDCA5,CDT1,CEP120,CEP135,CNOT2,CNOT6,CNOT6L,COA8,CSNK2A2,CUL3,DDX11,DKC1,DRG1,EDN1,ESPL1,FBXO7,FER,FMR1,GSK3A,GTF2H2,HNRNPA1,HNRNPU,KAT7,KMT2A,LCP1,MAP2K7,MAPK8,MECP2,MFN2,MIER1,MNS1,NAF1,NCKAP1,NEK2,NEK7,NSD3,NSFL1C,NSMCE2,NUP62,NUSAP1,PAF1,PAK1,PHB2,PHF1,PHIP,PLK4,PML,PPIF,PPP3CC,PPP3R1,RAB3GAP1,RAD21,RICTOR,RIF1,RNF31,RNF40,RPS6KA5,SART3,SETDB1,SFN,SH2B1,SIRT1,SLAIN2,SLF1,SMAD4,SMURF1,SNW1,STX18,SYT1,TADA2B,TFDP2,TNKS,TSC1,UBE2C,UBE2D3,UVRAG,VPS35,WASH3P,WASH6P,WASHC1 |
| GO_DOUBLE_STRAND_BREAK_REPAIR | 0.0e+00 | 0.0e+00 | 1930 | 251 | 59 | ACTR8,AP5Z1,APTX,ATM,BABAM1,BRCA2,CDCA5,CGAS,CHEK1,DDX1,DDX11,DMC1,ERCC8,GINS4,H4-16,HELB,HSF1,HUS1B,KAT5,KDM2A,MCM7,MCMDC2,MMS22L,MUS81,NSD2,NSMCE2,NUCKS1,PARP2,PAXX,PML,POLL,PPP4C,PPP4R2,RAD21,RAD51,RAD51AP1,RAD54L,RBBP8,RECQL,RECQL4,RFWD3,RIF1,RNF138,RPA2,RPA4,SHLD1,SHLD2,SLF1,TDP2,TENT4A,TERF2IP,TFIP11,TRIP12,UBQLN4,UIMC1,UVRAG,WDR48,XRCC4,YY1 |
| GO_MITOTIC_NUCLEAR_DIVISION | 0.0e+00 | 0.0e+00 | 1930 | 264 | 60 | ABRAXAS2,AKAP8,AKAP8L,ATM,AURKB,BUB1,CCNB1,CDC25C,CDC27,CDC6,CDCA5,CDT1,CENPK,CHEK1,CHMP4B,CHMP5,CLASP2,CUL3,DRG1,DYNC1LI1,EDN1,ESPL1,HNRNPU,INCENP,KIF18A,KIF2C,KNSTRN,KPNB1,MIS12,MTBP,NCAPH,NCAPH2,NDEL1,NEK2,NME6,NSFL1C,NSMCE2,NUF2,NUP62,NUSAP1,PHB2,PHF13,PHIP,PRC1,PSMG2,RACGAP1,RAD21,RAN,RCC1,SH2B1,SLF1,SMC4,STAG1,STAG2,TENT4A,TNKS,TPX2,UBE2C,USP16,VPS4A |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 553 | 87 | ABRAXAS2,ATXN3,AURKB,BRCA2,C2CD3,CAMSAP1,CCDC13,CCNB1,CDK1,CDK2,CENPA,CENPW,CEP120,CEP135,CEP57,CEP72,CEP76,CFAP157,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CKAP5,CLASP2,CLTC,CNTROB,DRG1,DYNC1LI1,ESPL1,FER,FGFR1OP,FOPNL,GSK3A,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HDGFL3,HNRNPU,KIAA0753,KIF18A,KIF2C,KNSTRN,KPNB1,MCIDAS,MCPH1,MECP2,NCOR1,NDEL1,NEK2,NEK7,NSFL1C,NUF2,NUP62,NUSAP1,ODF2,PAK1,PARD3,PCM1,PEX14,PLK4,PRC1,RACGAP1,RAE1,RAN,RASSF1,RCC1,RNF4,RSPH4A,SBDS,SENP6,SLAIN2,STAG1,STAG2,STARD9,TNKS,TPX2,TTC26,TUBA1C,TUBA8,TUBB,UVRAG,WDR62,WEE1 |
| GO_COVALENT_CHROMATIN_MODIFICATION | 0.0e+00 | 0.0e+00 | 1930 | 473 | 80 | ACTL6A,AKAP8,AKAP8L,ATF2,ATM,AURKB,BAP1,BAZ2A,BRCA2,BRD1,BRD4,BRMS1,BRMS1L,CCNA2,CCNB1,CDK1,CDK2,CHEK1,CREBBP,DCAF1,DDB1,DOT1L,DPF2,DR1,EZH1,FMR1,H1-4,HAT1,ING3,JMJD6,KANSL1,KANSL2,KAT5,KAT7,KDM2A,KDM6A,KDM6B,KMT2A,KMT2B,KMT5A,MAPK8,MBIP,MECP2,MIER1,MSL2,MSL3,MTA3,NSD2,NSD3,PAF1,PCGF5,PHF1,PRDM4,PWP1,RIF1,RNF40,RPS6KA5,SART3,SET,SETDB1,SIN3B,SIRT1,SMAD4,SNW1,SUPT6H,SUPT7L,TADA1,TADA2B,TAF5L,TAF9B,TET3,TRIP12,UBE2A,UIMC1,USP16,USP21,USP3,USP7,WAC,ZNF335 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1930 | 1198 | 135 | AATF,ACTR3,AGO2,AKAP8L,ATAD2,ATF1,ATF2,ATF4,ATM,BCL2L12,BRD4,CCNK,CCNT1,CCNT2,CDK12,CDK5RAP3,CKAP2,CREB1,CREBBP,CRLF3,CRTC3,CTBP2,DOT1L,DPF2,DR1,E2F3,EDN1,EIF2A,ELF5,ELK1,ELL,EXOSC9,EZH1,FOXC1,FOXJ2,FOXJ3,FOXK2,FUBP3,GALR2,GMEB1,GSK3A,GTF2F1,HMGB2,HNRNPK,HNRNPU,HOXA9,HOXC11,HSF1,HSF2,JMJD6,KAT5,KAT7,KDM6B,KLF4,KMT2A,MAFG,MCIDAS,MED1,MED10,MED13,MED17,MED6,MLLT10,NFE2L2,NFKB1,NFYC,NHLH1,NOTCH1,NR2C2,NRF1,NRL,NUCKS1,PAF1,PBX3,PCGF5,PHIP,PKNOX1,PLAGL2,PPP3R1,PPRC1,PRDM4,PSMC2,PSMC3,PSMC4,PSMC6,PTOV1,RBM15,RBMX,REL,RNF10,RNF4,RPS6KA5,SENP1,SIRT1,SIX4,SLC11A1,SMAD4,SNW1,SOX15,SP3,SUMO2,SUPT6H,TAF2,TAF9B,TBR1,TBX3,TCF20,TCF3,TCF7L2,TEAD4,TET3,TFDP2,TNIP2,TNKS,TOP2A,UBB,UBC,UBE3A,USP16,YAP1,YES1,YY1,ZBTB49,ZEB1,ZEB2,ZNF131,ZNF148,ZNF24,ZNF300,ZNF382,ZNF597,ZNF613,ZNF639,ZNF649,ZNF835 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1930 | 1994 | 185 | ABL2,AIDA,AKAP8,AKAP8L,ARAF,ATM,AURKB,AXIN1,BAG4,BANK1,BRAP,BRD4,BTK,BUB1,C3orf33,CACTIN,CAMK2G,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK1,CDK11A,CDK12,CDK17,CDK2,CDK5RAP3,CDKL1,CHEK1,CHORDC1,CLCF1,CLK1,CLK3,CNOT9,COPS2,CREB1,CSNK1G1,CSNK2A2,CUL1,CUL3,DAXX,DBNDD2,DCAF1,DNAJA1,DVL3,DYRK2,EDN1,EIF2A,FAF1,FBXO7,FBXW11,FER,FGF22,FGFR1OP,FMR1,FRS3,FXR1,GFRAL,GGNBP2,GRK7,GSK3A,GTF2H2,HGS,HIPK1,HSF1,IBTK,ILF3,IPO7,IQGAP3,IRAK3,ITCH,JTB,KLB,KLF4,LEMD2,LYN,MAP2K7,MAP4K4,MAPK6,MAPK8,MASTL,MBIP,MED1,MELK,MYLK2,NCOR1,NEK2,NEK7,NFKB1,NOTCH1,NUP62,PABPN1,PAK1,PAK2,PARD3,PARP14,PDCD10,PDCL3,PDIK1L,PEA15,PHB2,PHIP,PLK4,PML,PPIL4,PPP2R5D,PPP2R5E,PRKAB1,PRKRIP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PWP1,RAD51,RAP2C,RASA2,RHBDD3,RICTOR,RIOK3,RPS6KA5,SCYL1,SFN,SIK1,SIK1B,SIRT1,SLC11A1,SMAD4,SMG1,SMG8,SOD1,SPDYA,SRPK1,STK10,STK19,STK35,TAB2,TELO2,TERF2IP,TLK2,TMEM119,TNFRSF10A,TNIP2,TNKS,TPX2,TRAF2,TRAF4,TSC1,TWF1,TYRO3,UBB,UBC,UBE2K,UVRAG,WDR83,WEE1,WNT9B,YES1,ZEB2,ZFP91,ZNF622,ZNF675 |
| GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 1930 | 861 | 110 | AGO2,ALKBH1,ATF4,BANK1,CASC3,CELF1,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,DCP1A,DCP2,DDX1,DIS3,DKC1,DPH2,DPH5,DPH7,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3H,EIF4B,EIF4G2,EIF5,EIF5A,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FMR1,FXR1,GSPT1,H4-16,HNRNPL,HNRNPU,HSPA8,ILF3,KBTBD8,MATR3,MTIF2,MTPN,NAF1,NCOR1,NGRN,NSUN3,NUDT21,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OGFOD1,PABPC1,PAIP1,PATL2,POLDIP3,PPP1R15A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,PUS7,RAE1,RAN,RBM10,RBM4B,RBM8A,RC3H1,RPL22,RPUSD4,SARNP,SET,SLC11A1,SNIP1,SRRT,TACO1,TENT4A,TSC1,UBB,UBC,UPF3B,USP16,YTHDF2,YTHDF3,ZC3H14,ZC3H7A,ZCCHC4 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 267 | 59 | ATM,AURKB,BABAM1,BUB1,CCNB1,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL1,DTL,DYNC1LI1,FBXO7,HUS1B,KLF4,MDM4,NAE1,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RAD21,RFWD3,RPA2,SFN,SYF2,TFDP2,TOPBP1,UIMC1,USP47,VPS4A,WEE1 |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 752 | 101 | ABRAXAS2,ACTR3,AP3B1,ATXN3,AURKB,BAG3,BLOC1S2,BRCA2,C2CD3,CAMSAP1,CCDC13,CCNB1,CDK1,CDK2,CENPA,CENPW,CEP120,CEP135,CEP57,CEP72,CEP76,CFAP157,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CKAP5,CLASP2,CLTC,CNTROB,DRG1,DYNC1LI1,ESPL1,FER,FGFR1OP,FOPNL,GSK3A,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HDGFL3,HNRNPU,HSPA8,KIAA0753,KIF18A,KIF21A,KIF2C,KNSTRN,KPNB1,MCIDAS,MCPH1,MECP2,MEMO1,NCOR1,NDEL1,NEK2,NEK7,NSFL1C,NUF2,NUP62,NUSAP1,ODF2,PAK1,PARD3,PCM1,PEX14,PLK4,PRC1,RAB1A,RAB21,RACGAP1,RAE1,RAN,RASSF1,RCC1,RNF4,RSPH4A,SBDS,SENP6,SLAIN2,SOD1,STAG1,STAG2,STARD9,TMEM108,TNKS,TPX2,TTC26,TUBA1C,TUBA8,TUBB,UBB,UVRAG,VAMP7,VBP1,WDR62,WEE1 |
| GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 339 | 66 | ATF2,ATM,AURKB,BUB1,CCNB1,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL1,DYNC1LI1,E4F1,FBXO7,FOXC1,HUS1B,KLF4,MCPH1,MDM4,MTBP,MUS81,NAE1,NME6,PML,PRCC,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PSMG2,RAD21,RFWD3,RPA2,SFN,SYF2,TFDP2,TNKS,TOP2A,TOPBP1,USP47,VPS4A,WEE1 |
| GO_DNA_INTEGRITY_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1930 | 158 | 46 | ATF2,ATM,BABAM1,CCNB1,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL4A,DOT1L,DTL,FBXO6,FEM1B,HINFP,HUS1B,INTS7,MDM4,MUS81,NAE1,PEA15,PML,PTPN11,RAD1,RFWD3,RNASEH2B,RPA2,RPA4,SFN,SYF2,TFDP2,THOC1,THOC5,TOP2A,TOPBP1,UIMC1,WAC |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 1220 | 134 | ABCA1,ABL2,ACD,ACTR3,AKAP8,AKAP8L,AP2B1,ATAD1,ATF1,ATM,ATMIN,AURKB,BAG4,BAIAP2L1,BAP1,BID,BIN1,BRD4,CAPN2,CBLL1,CCNB1,CDCA5,CDT1,CEP120,CEP135,CLASP2,CNOT2,CNOT6,CNOT6L,COA8,CREB1,CSNK2A2,CUL3,CUL4A,DDB1,DDX11,DKC1,DNM2,DRG1,DVL3,EDN1,EIF5A,ESPL1,FAF1,FBXO7,FER,FMR1,GSK3A,GTF2H2,HNRNPA1,HNRNPK,HNRNPU,HSF1,ITSN2,KAT7,KMT2A,LCP1,LRRTM2,LYN,MAP2K7,MAP4K4,MAPK6,MAPK8,MECP2,MFN2,MIER1,MNS1,NAF1,NCKAP1,NDEL1,NEK2,NEK7,NFE2L2,NSD3,NSFL1C,NSMCE2,NUP62,NUSAP1,PAF1,PAK1,PHB2,PHF1,PHIP,PLAA,PLK4,PML,PPIF,PPP1R15A,PPP3CC,PPP3R1,PSMC2,PSMC3,PSMC4,PSMC6,PTPN23,RAB21,RAB3GAP1,RAD21,RICTOR,RIF1,RNF31,RNF40,RPA2,RPS6KA5,RUFY3,SART3,SETDB1,SF3A2,SFN,SH2B1,SIRT1,SLAIN2,SLF1,SMAD4,SMURF1,SNW1,SRPX2,STX18,SYT1,TADA2B,TFDP2,TNKS,TSC1,TWF1,UBE2C,UBE2D3,UVRAG,VAMP7,VPS35,WASF2,WASH3P,WASH6P,WASHC1,ZEB2 |
| GO_CELL_CYCLE_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1930 | 217 | 53 | ATF2,ATM,AURKB,BABAM1,BUB1,CCNB1,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL4A,DOT1L,DTL,DYNC1LI1,FBXO6,FEM1B,HINFP,HUS1B,INTS7,MDM4,MUS81,NAE1,PEA15,PML,PRCC,PSMG2,PTPN11,RAD1,RFWD3,RNASEH2B,RPA2,RPA4,SFN,SYF2,TFDP2,THOC1,THOC5,TOP2A,TOPBP1,UIMC1,VPS4A,WAC,WEE1 |
| GO_NUCLEAR_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 263 | 58 | ABRAXAS2,ACTR3,AKAP8,AKAP8L,ATM,AURKB,BUB1,CCNB1,CCNB1IP1,CDC27,CDC6,CDCA5,CDT1,CENPK,CENPQ,CHMP4B,CHMP5,CUL3,DDX11,DMC1,DYNC1LI1,ESPL1,FANCM,HNRNPU,INCENP,KIF18A,KIF2C,KNSTRN,KPNB1,MCMDC2,MIS12,MSH4,MUS81,NCAPH,NCAPH2,NEK2,NSMCE2,NUF2,NUP62,NUSAP1,PHB2,PHF13,PRC1,PSMG2,RACGAP1,RAD21,RAN,RCC2,SLF1,SMC1B,SMC4,STAG1,STAG2,TENT4A,TNKS,TOP2A,VPS4A,WAPL |
| GO_PROTEIN_POLYUBIQUITINATION | 0.0e+00 | 0.0e+00 | 1930 | 312 | 63 | CDC16,CDC27,CUL1,CUL3,DTL,ERCC8,FBXL3,FBXO11,FBXO2,FBXO30,FBXO6,FBXO7,FBXW11,FBXW2,ITCH,MARCHF7,NMI,PLAA,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RBBP6,RC3H1,RLIM,RNF126,RNF19B,RNF31,RNF4,RNF40,RNF6,RUSC1,SMURF1,TNKS,TRAF2,TRIM56,TRIP12,UBB,UBC,UBE2A,UBE2C,UBE2D3,UBE2K,UBE2T,UBE3A,XIAP,ZFP91,ZNF738 |
| GO_MRNA_3_END_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 98 | 37 | ALYREF,CASC3,CCNB1,CCNT1,CDC40,CPEB1,CPSF2,CPSF6,CPSF7,FIP1L1,GRSF1,HSF1,LSM11,MAGOHB,MTPAP,NUDT21,PABPC1,PABPN1,PAF1,PAPOLA,POLDIP3,RBM8A,RNF40,RNPS1,SARNP,SCAF8,SLBP,SLU7,SNRPA,SRSF11,SRSF4,THOC1,THOC5,UPF3B,VIRMA,ZC3H14,ZC3H3 |
| GO_NUCLEAR_EXPORT | 0.0e+00 | 0.0e+00 | 1930 | 195 | 50 | AKAP8L,ALYREF,ANP32B,BAG3,CASC3,CDC40,CPSF2,CPSF6,CTDSPL2,EIF5A,FIP1L1,HNRNPA1,HSPA9,MAGOHB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,PPM1A,PTPN11,RAE1,RAN,RANGAP1,RBM22,RBM26,RBM27,RBM8A,RNPS1,SARNP,SFN,SLBP,SLU7,SMG1,SMG5,SMG7,SMURF1,SRSF11,SRSF4,SUPT6H,TCF7L2,THOC1,THOC5,TSC1,UPF3B,XPO4 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1930 | 751 | 99 | AIDA,ATF4,ATM,ATXN3,AXIN1,BABAM1,BAG1,BAG2,BAG3,BAG4,BCL2L12,BID,CAMK2G,CGAS,CHEK1,CHORDC1,CREBBP,CUL4A,DAXX,DDX11,DERL2,DNAJA1,DNAJB1,DNAJB6,DNAJC2,DNAJC7,DVL3,EDN1,EEF1E1,EID3,ERCC8,FBXO7,FEM1B,FMR1,FXR1,HELB,HIC1,HNRNPK,HSF1,HSPA8,HSPH1,ITCH,KLF4,KMT5A,LYN,MAP2K7,MAP4K4,MARCHF7,NCOR1,NDEL1,NFE2L2,NONO,NSD2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OXR1,PAK1,PAWR,PDCD10,PML,PPP1R15A,PPP4C,PPP4R2,RAD51,RAD51AP1,RAE1,RFWD3,RIF1,RNASEH2B,RPA2,SHLD1,SHLD2,SIRT1,SLC7A11,SLF1,SMG1,SOD1,TAF9B,TERF2IP,TFIP11,THOC1,THOC5,TRAF2,TRAF4,TRIP12,TSC1,UBQLN4,UIMC1,USP1,USP14,USP47,YJU2,ZEB2,ZNF622,ZNF675 |
| GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 540 | 82 | AGO2,AP1G1,BTK,CACTIN,CCNT1,CD226,CGAS,CHMP4B,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDB1,DDX60,FBXW11,FMR1,GPATCH3,GTF2F1,HMGB2,IL18RAP,IRAK3,ITCH,KPNA2,LHFPL2,LYN,MATR3,MED1,MUC13,NELFA,NFKB1,NONO,NOTCH1,NPLOC4,NUCKS1,OTUD4,PABPC1,PAK1,PAK2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,SNW1,SRPK1,TAB2,TICAM1,TNIP2,TOP2A,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAPA,VPS4A,XIAP,ZNF639 |
| GO_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 229 | 53 | AKAP8L,ALYREF,ATM,CASC3,CDC40,CKAP5,CPSF2,CPSF6,DCP2,DKC1,EIF5A,EXOSC10,EXOSC3,FIP1L1,FMR1,HNRNPA1,HNRNPA3,HNRNPU,HSF1,MAGOHB,NAF1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,PRPF18,RAE1,RAN,RBM26,RBM27,RBM8A,RNPS1,SARNP,SLBP,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,TNKS,TSC1,UPF3B,YY1,ZC3H3 |
| GO_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 189 | 48 | AKAP8,AKAP8L,ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDCA5,CDT1,CENPK,CHMP4B,CHMP5,CUL3,DDX11,DYNC1LI1,ESPL1,HNRNPU,INCENP,KIF18A,KIF2C,KNSTRN,KPNB1,MIS12,NCAPH,NCAPH2,NEK2,NSMCE2,NUF2,NUP62,NUSAP1,PHB2,PHF13,PRC1,PSMG2,RACGAP1,RAD21,RAN,SLF1,SMC1B,SMC4,STAG1,STAG2,TENT4A,TNKS,TOP2A,VPS4A,WAPL |
| GO_DNA_CONFORMATION_CHANGE | 0.0e+00 | 0.0e+00 | 1930 | 322 | 62 | AKAP8,AKAP8L,ANP32B,CCNB1,CDCA5,CDK1,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,CHTF18,CUL4A,DAXX,DDB1,DDX1,DDX11,DFFB,ERCC8,GINS4,GRWD1,GTF2H2,H1-4,H2BC3,H4-16,HAT1,HELB,HJURP,HMGB2,HP1BP3,IGHMBP2,MCM7,MCPH1,MIS18A,NAP1L1,NAP1L4,NCAPH,NCAPH2,NUSAP1,PAF1,PHF13,RAD51,RAD54L,RAD54L2,RBBP4,RECQL,RECQL4,SART3,SET,SMC4,SPTY2D1,SRPK1,SUPV3L1,TENT4A,TOP2A,TOP3A,UBB,UBC,WAPL |
| GO_NUCLEAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 347 | 64 | AKAP8L,ALYREF,ANP32B,BAG3,CASC3,CDC40,CPSF2,CPSF6,CTDSPL2,EIF5A,FAM53C,FIP1L1,HNRNPA1,HSPA9,IPO11,IPO7,KPNA2,KPNA4,KPNB1,MAGOHB,MED1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NUP62CL,NXT1,PABPN1,PHB2,PML,POLDIP3,PPM1A,PTPN11,RAB18,RAE1,RAN,RANGAP1,RBM22,RBM26,RBM27,RBM8A,RGPD6,RNPS1,SARNP,SFN,SLBP,SLU7,SMG1,SMG5,SMG7,SMURF1,SNRPB,SRSF11,SRSF4,SUPT6H,TCF7L2,THOC1,THOC5,TNPO2,TSC1,UPF3B,XPO4 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 391 | 68 | ATM,AURKB,BRCA2,BRD4,CCNB1,CCNK,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDCA5,CDK1,CDK2,CDT1,CEP120,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CSPP1,CUL3,CUL4A,DDX11,DTL,DYNC1LI1,EDN1,ESPL1,HNRNPU,HSF1,KLHL18,LSM11,MDM4,MECP2,MED1,MTA3,MTBP,NSFL1C,NSMCE2,NUP62,NUSAP1,PAF1,PGGT1B,PHB2,PHIP,PLK4,PML,PTPN11,RACGAP1,RAD21,RCC2,SFN,SH2B1,SLF1,SOX15,SPDYA,TBX3,TFDP2,THOC1,THOC5,UBE2C,UHRF2,ZNF16 |
| GO_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1930 | 267 | 56 | ALYREF,ATF1,ATM,BRCA2,CCNA2,CDC6,CDK1,CDK2,CDT1,CHEK1,CHTF18,DDX11,DNAJC2,DTL,E4F1,FAF1,FANCM,GINS4,GRWD1,HELB,IGHMBP2,KAT5,KAT7,KIN,MCIDAS,MCM7,MCMDC2,MMS22L,NAP1L1,NUCKS1,OBI1,ORC6,POLE,POLK,POLL,RAD1,RAD51,RBBP4,RBBP6,RBBP8,RECQL,RECQL4,RFC1,RFWD3,RNASEH2A,RPA2,RPA4,RRM1,SDE2,SET,STOML2,TBRG1,THOC1,TOP3A,TOPBP1,WAPL |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1670 | 157 | ACTR3,AP1G1,AP3B1,ATM,ATXN1L,BANK1,BTK,BTN2A1,BTN2A3P,C12orf4,CACTIN,CASP3,CD200R1,CD226,CD274,CD300LG,CD3G,CFHR2,CGAS,CLCF1,CLEC4A,CNOT4,CNPY3,CREB1,CREBBP,CTSL,CUL1,CUL4A,DDX1,DDX60,DENND1B,DPF2,EDN1,EIF2B4,ELF2,ERAP1,EXOSC3,FBXO7,FBXW11,FER,FOXC1,GNRH1,GPATCH3,H4-16,HMGB2,HOXA9,HSPA9,HSPH1,IGHV3-43,IGKV1D-33,IL18RAP,ILRUN,IRAK3,ITCH,KMT2A,KMT2B,LPXN,LYN,MAP2K7,MAPK8,MARCHF7,MATR3,MED1,MICB,MUC13,N4BP2L2,NCKAP1,NFE2L2,NFKB1,NFKBID,NKAP,NMI,NONO,NOTCH1,NPLOC4,NSD2,NUDT21,OTUD4,PAF1,PAK1,PAK2,PARP14,PAWR,PCBP2,POLR3C,POLR3F,PPP3R1,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,PUS7,RAB11FIP2,RBM15,RC3H1,RHBDD3,RIF1,RIOK3,RNF31,RPS6KA5,SART1,SENP1,SH3KBP1,SHLD1,SHLD2,SIRT1,SLC11A1,SLC7A11,SOCS6,SOD1,SPINK5,STK10,STOML2,SUPT6H,TAB2,TCF3,THOC1,TICAM1,TNIP2,TRAF2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,VAV2,WASF2,XIAP,YAP1,YES1,YTHDF2,YTHDF3,ZEB1,ZNF16,ZNF335,ZNF675 |
| GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 199 | 48 | AGO2,CNOT6L,DCP1A,DCP2,DHX34,DIS3,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FMR1,FXR1,HNRNPU,HSPA8,PABPC1,PAIP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RBM10,RC3H1,SET,SLC11A1,TENT4A,UBB,UBC,YTHDF2,YTHDF3,ZC3H14,ZC3HAV1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 105 | 36 | ATM,AURKB,BABAM1,CDC6,CDK1,CDK5RAP3,CHEK1,CUL1,DTL,HUS1B,NAE1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAD21,SYF2,TOPBP1,UIMC1,USP47,VPS4A |
| GO_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 835 | 102 | ABRAXAS2,ACTR3,ATG12,ATMIN,ATXN2L,AURKB,BAG3,BRIX1,C2CD3,CCDC13,CDK1,CDK2,CDKL1,CENPA,CENPK,CENPT,CENPW,CEP120,CEP135,CEP57,CEP72,CEP76,CEP89,CFAP157,CHMP4B,CHMP5,CKAP5,CNOT2,CNOT6,CNOT6L,CNTROB,DNM2,DRG1,EDN1,EIF2A,FBF1,FGFR1OP,FOPNL,GABARAPL1,GORASP2,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HGS,HNRNPU,IQCB1,KIAA0753,KPNB1,LCP1,LRRTM2,MCIDAS,MFN2,MIS12,MNS1,MRPS2,MTERF4,NCOR1,NEK2,NEK7,NIP7,NOTCH1,NSFL1C,NUP62,ODF2,OGFOD1,PATL2,PCM1,PLK4,PPAN,PTPN23,PUM2,RAB14,RAB1A,RAB38,RAB3GAP1,RACGAP1,RC3H1,RCC1,RNF4,RO60,RSPH4A,SBDS,SENP6,SIX4,SMAD4,SMURF1,STAG1,STAG2,STAM,STARD9,STX18,TCHP,TNKS,TPX2,TTC26,TUBB,VPS37A,VPS4A,WDR62 |
| GO_PEPTIDYL_LYSINE_MODIFICATION | 0.0e+00 | 0.0e+00 | 1930 | 397 | 67 | ACTL6A,ATF2,BRCA2,BRD1,BRD4,CHEK1,CREBBP,DOT1L,DPF2,DR1,EEF1AKMT2,EZH1,H1-4,HAT1,ING3,JMJD6,KANSL1,KANSL2,KAT5,KAT7,KDM6A,KMT2A,KMT2B,KMT5A,MBIP,MECP2,METTL21A,MSL2,MSL3,NSD2,NSD3,NSMCE2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PHF1,PWP1,RAE1,RANGAP1,RIF1,RPS6KA5,SENP1,SENP5,SENP6,SENP7,SET,SETD4,SETDB1,SIRT1,SMAD4,SNW1,SUMO2,SUMO3,SUPT6H,SUPT7L,TADA1,TADA2B,TAF5L,TAF9B,TET3,UBA2,UBE2I,USPL1,ZNF335 |
| GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 353 | 63 | ACD,ALYREF,ATM,AURKB,BABAM1,CDK2,CDT1,CGAS,CHEK1,CHTF18,CLCF1,CUL4A,DCP2,DDX11,DKC1,DNAJC2,ERCC8,EXOSC10,EXOSC3,GSK3A,H1-4,HELB,HNRNPA1,HNRNPU,HSF1,KLF4,KMT2A,KPNA2,MAP2K7,MECP2,MIS18A,NAF1,NEK2,NEK7,NSD2,NUCKS1,OTUD4,PML,PPP4C,PPP4R2,RAD51,RAD51AP1,RIF1,RPA2,SH2B1,SHLD1,SHLD2,SIRT1,SLF1,SMG1,SMG5,SMG7,SUPT6H,TERF2IP,TFIP11,THOC1,TNKS,TRIP12,UBQLN4,UIMC1,USP1,USP7,ZSCAN4 |
| GO_SPINDLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 169 | 44 | ABRAXAS2,AURKB,CCNB1,CENPW,CEP120,CEP72,CHMP4B,CHMP5,CKAP5,CLASP2,CLTC,DRG1,ESPL1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HNRNPU,KNSTRN,KPNB1,MECP2,NCOR1,NEK2,NEK7,NUF2,NUP62,PRC1,RACGAP1,RAE1,RAN,RCC1,RNF4,SBDS,SENP6,STAG1,STAG2,STARD9,TNKS,TPX2,TUBB,UVRAG,WDR62 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 777 | 97 | AGO2,AP1G1,BTK,CACTIN,CCNK,CCNT1,CD226,CGAS,CHMP4B,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDB1,DDX60,ERAP1,FBXW11,FMR1,GPATCH3,GTF2F1,HMGB2,IL18RAP,ILF3,ILRUN,IRAK3,ITCH,KPNA2,LHFPL2,LYN,MATR3,MED1,MICB,MUC13,NELFA,NFKB1,NMI,NONO,NOTCH1,NPLOC4,NUCKS1,OTUD4,PABPC1,PAK1,PAK2,PARP14,PCBP2,PML,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,SETDB1,SNW1,SPINK5,SRPK1,TAB2,TICAM1,TNIP2,TOP2A,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAPA,VPS4A,XIAP,YTHDF2,YTHDF3,ZC3HAV1,ZNF639 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1880 | 167 | AIDA,AKAP8,AKAP8L,ANKLE2,ARAF,ARRDC3,ATM,AXIN1,BAG2,BAG4,BANK1,BRD4,BRMS1,C3orf33,CACTIN,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK1,CDK12,CDK5RAP3,CHEK1,CHORDC1,CLCF1,CNOT9,CUL3,DAXX,DBNDD2,DCUN1D2,DNAJA1,DVL3,EDN1,FAF1,FANCI,FANCM,FBXO2,FBXO7,FEM1B,FER,FGFR1OP,FMR1,FXR1,GFRAL,GGNBP2,GSK3A,HGS,HSF1,IBTK,IPO7,IQGAP3,IRAK3,ITCH,JTB,KAT5,KAT7,KLB,KLF4,KMT2A,KMT2B,LEMD2,LYN,MAP2K7,MAP4K4,MAPK8,MARCHF7,MASTL,MBIP,MECP2,MTBP,NCOR1,NMI,NOTCH1,NSD3,NUP62,OTUD4,OXR1,PAF1,PAK1,PAK2,PARD3,PARP14,PDCD10,PDCL3,PEA15,PEF1,PHB2,PHF1,PHIP,PLAA,PML,POMT2,PPIL4,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R1B,PPP2R5D,PPP2R5E,PPP4R2,PPP6R1,PRKRIP1,PTPN11,PWP1,RAB1A,RAB3GAP1,RAD51,RAP2C,RCHY1,RICTOR,RIF1,RNF40,RPS6KA5,RPS7,SART3,SET,SFN,SIRT1,SLC11A1,SMAD4,SMG8,SNW1,SOD1,SPDYA,SPOPL,STK10,SUPT6H,TAB2,TADA2B,TELO2,TERF2IP,TICAM1,TMEM119,TNFRSF10A,TPX2,TRAF2,TRAF4,TRIP12,TSC1,TWF1,UBB,UBC,UBE2C,UBE2I,UBE2K,UBE3A,UFL1,UVRAG,WASHC1,WDR48,WNT9B,XIAP,YES1,ZEB2,ZFP91,ZNF335,ZNF622,ZNF675 |
| GO_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 85 | 32 | DPF2,FOXC1,HSPA9,ITCH,KMT2A,N4BP2L2,NFE2L2,NOTCH1,NUDT21,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUS7,TCF3,YAP1,YTHDF2 |
| GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 240 | 51 | AKAP8L,ALYREF,CASC3,CDC40,CKAP5,CPSF2,CPSF6,EIF5A,FIP1L1,FMR1,HNRNPA1,HNRNPA3,HNRNPU,HSF1,MAGOHB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,RAE1,RAN,RBM26,RBM27,RBM8A,RNPS1,SARNP,SLBP,SLC25A19,SLC25A25,SLC25A32,SLC25A33,SLC25A5,SLC35B1,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,TNKS,TSC1,UPF3B,ZC3H3 |
| GO_MITOTIC_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 151 | 41 | AKAP8,AKAP8L,ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDCA5,CDT1,CENPK,CHMP4B,CHMP5,CUL3,DYNC1LI1,ESPL1,HNRNPU,INCENP,KIF18A,KIF2C,KNSTRN,KPNB1,MIS12,NCAPH,NCAPH2,NEK2,NSMCE2,NUF2,NUP62,NUSAP1,PHF13,PRC1,PSMG2,RACGAP1,RAD21,RAN,SLF1,SMC4,TENT4A,TNKS,VPS4A |
| GO_PEPTIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 879 | 103 | AARSD1,ABCF1,AGO2,ALKBH1,APH1A,ATF4,BANK1,BIN1,CASC3,CASP3,CDKAL1,CELF1,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,DDX1,DENR,DPH2,DPH5,DPH7,DRG1,EEF1B2,EEF1E1,EIF1AD,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF4B,EIF4G2,EIF5,EIF5A,ERAP1,ERO1B,FMR1,FXR1,GSK3A,GSPT1,GSR,HNRNPL,HSPA14,IGHMBP2,ILF3,KBTBD8,LTO1,LVRN,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTIF2,MTPN,MTRF1L,NARS1,NFE2L2,NGRN,NPEPPSP1,NSUN3,OGFOD1,PABPC1,PAIP1,PATL2,POLDIP3,PPP1R15A,PUM1,PUM2,PUS7,QRSL1,RBM4B,RBM8A,RC3H1,RPL21,RPL22,RPS7,RPUSD4,SARNP,SEC11A,SLC7A11,SOD1,SPCS2,TACO1,TSC1,UPF3B,USP16,WARS2,YTHDF2,YTHDF3,ZC3H15,ZCCHC4 |
| GO_ESTABLISHMENT_OF_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 196 | 46 | AKAP8L,ALYREF,ATM,CASC3,CDC40,CKAP5,CPSF2,CPSF6,EIF5A,FIP1L1,FMR1,HNRNPA1,HNRNPA3,HNRNPU,HSF1,MAGOHB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,RAE1,RAN,RBM26,RBM27,RBM8A,RNPS1,SARNP,SLBP,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,TNKS,TSC1,UPF3B,ZC3H3 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1930 | 860 | 101 | ATF2,ATXN1L,AURKB,BAG3,BRMS1,BRMS1L,CDK2,CHCHD3,CNOT2,COPS2,CREBBP,CUL3,DCAF1,DNAJB1,DPF2,DR1,E2F3,E4F1,EDN1,EZH1,FOXC1,FOXK2,H1-4,HIC1,HINFP,HNRNPU,HSF1,IGHMBP2,KAT5,KLF4,KMT5A,LRRFIP1,MCPH1,MDM4,MECP2,MED1,MIER1,MIER3,MTA3,MXD1,N4BP2L2,NCOR1,NELFA,NFKB1,NKAP,NOTCH1,NSD2,OTUD7B,PAF1,PAWR,PER3,PPM1A,RBM10,REL,RFC1,RIF1,RLIM,SARNP,SCAF4,SCAF8,SIN3B,SIRT1,SMAD4,SNW1,SOX15,SP3,TAF9B,TBR1,TBX3,TCERG1,TCF3,TCF7L2,THAP1,UBB,UBC,UBE2D3,UBE2I,USP3,YY1,ZBTB14,ZBTB2,ZBTB26,ZBTB34,ZEB1,ZEB2,ZNF131,ZNF136,ZNF140,ZNF148,ZNF157,ZNF189,ZNF202,ZNF263,ZNF296,ZNF382,ZNF568,ZNF613,ZNF649,ZNF668,ZNF675,ZNF835 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 297 | 56 | ATM,AURKB,BRD4,CCNB1,CDC25A,CDC25C,CDC6,CDCA5,CDK1,CDK2,CDT1,CEP120,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CSPP1,CUL3,CUL4A,DDX11,DTL,DYNC1LI1,EDN1,ESPL1,HNRNPU,KLHL18,LSM11,MDM4,MECP2,MED1,MTA3,MTBP,NSFL1C,NSMCE2,NUP62,NUSAP1,PAF1,PHB2,PHIP,PLK4,PML,RACGAP1,RAD21,RCC2,SFN,SH2B1,SLF1,SOX15,TFDP2,UBE2C,UHRF2,ZNF16 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1930 | 1748 | 157 | AATF,ADNP2,AIFM2,AIPL1,ALKBH1,ANKLE2,ANP32B,AP2B1,APH1A,ARAF,ARL6IP1,ATAD3A,ATF2,ATF4,ATM,AURKB,BAG1,BAG3,BAG4,BCL2L12,BCL2L2,BID,BIN1,BNIP1,BNIP2,BRMS1,BTBD10,BTK,C3orf38,CAPN10,CAPN2,CASP10,CASP3,CD200R1,CD274,CD3G,CDK1,CHMP4B,CLCF1,COA8,CREB1,CREBBP,CSNK2A2,DAXX,DDB1,DNAJA1,DNAJB6,DNM2,E2F3,EDN1,EEF1E1,EGLN2,ELK1,FAF1,FBXO11,FBXO7,FEM1B,FGD1,FOXC1,FRZB,GFRAL,GNA13,GNRH1,GPR75,GSK3A,HMGB2,HNRNPK,HSF1,HSPA9,ING3,ITCH,KHDC1L,KLF4,LYN,MAP4K4,MAPK8,MARCHF7,MDM4,MECP2,MED1,MELK,MFN2,MTCH1,NAA35,NAE1,NDUFS3,NFE2L2,NFKB1,NFKBID,NONO,NOTCH1,NUP62,OXR1,PAK2,PARP2,PAWR,PDCD10,PEA15,PHB2,PHIP,PLAGL2,PML,PPIF,PPP2R1B,PPP3CC,PPP3R1,PSMC1,PSMG2,RABGGTB,RAD18,RASSF3,RBM10,RBM25,REL,RNPS1,RPS7,SAP30BP,SENP1,SET,SFN,SIK1,SIRT1,SIX4,SLC25A5,SLC7A11,SMAD4,SOD1,SUPV3L1,TAF9B,TAX1BP1,TBX3,TCF7L2,TFDP2,TNFRSF10A,TNFRSF10D,TNIP2,TOP2A,TRAF2,TRAF4,TRAF5,TSC1,TYRO3,UBB,UBC,UBE2M,UBE2Z,UFL1,UNG,USP47,VAV2,VDAC2,VPS35,XIAP,YAP1,ZC3HC1,ZNF16,ZNF622 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 400 | 65 | AP1G1,BTK,CACTIN,CD226,CD274,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,FBXW11,GPATCH3,HMGB2,IL18RAP,IRAK3,ITCH,LYN,MATR3,MED1,MUC13,NFKB1,NONO,NPLOC4,OTUD4,PAK1,PAK2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,XIAP |
| GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 522 | 75 | AP1G1,BTK,CACTIN,CD226,CD274,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,ERAP1,FBXW11,GPATCH3,HMGB2,IL18RAP,ILRUN,IRAK3,ITCH,LYN,MATR3,MED1,MICB,MUC13,NFKB1,NMI,NONO,NPLOC4,OTUD4,PAK1,PAK2,PARP14,PCBP2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,SPINK5,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,XIAP,YTHDF2,YTHDF3 |
| GO_PEPTIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 736 | 91 | AARSD1,ABCF1,AGO2,ALKBH1,ATF4,BANK1,CASC3,CDKAL1,CELF1,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,DDX1,DENR,DPH2,DPH5,DPH7,DRG1,EEF1B2,EEF1E1,EIF1AD,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF4B,EIF4G2,EIF5,EIF5A,FMR1,FXR1,GSPT1,HNRNPL,HSPA14,IGHMBP2,ILF3,KBTBD8,LTO1,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTIF2,MTPN,MTRF1L,NARS1,NFE2L2,NGRN,NSUN3,OGFOD1,PABPC1,PAIP1,PATL2,POLDIP3,PPP1R15A,PUM1,PUM2,PUS7,QRSL1,RBM4B,RBM8A,RC3H1,RPL21,RPL22,RPS7,RPUSD4,SARNP,SLC7A11,TACO1,TSC1,UPF3B,USP16,WARS2,YTHDF2,YTHDF3,ZC3H15,ZCCHC4 |
| GO_RNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 0.0e+00 | 1930 | 136 | 38 | AKAP8L,ALYREF,CASC3,CDC40,CPSF2,CPSF6,EIF5A,FIP1L1,HNRNPA1,MAGOHB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,RAE1,RAN,RBM26,RBM27,RBM8A,RNPS1,SARNP,SLBP,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,TSC1,UPF3B |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 622 | 82 | ACTR3,AP3B1,ARCN1,ATM,BIN1,BLOC1S2,BTK,C12orf4,C2CD3,CCNB1,CDCA5,CDK1,CDT1,CENPA,CENPQ,CEP120,CEP135,CEP57,CEP72,CEP76,CEP89,CHMP4B,CHMP5,CKAP5,CLASP2,CNIH1,CTBP2,CUL3,DNM2,ESPL1,FBF1,FER,FGFR1OP,GOSR1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HNRNPU,IQCB1,KIF18A,KIF2C,KLHL21,KPNB1,KXD1,LYN,MCPH1,MFN2,MIS12,MYO19,NDEL1,NEK2,NSFL1C,NUF2,NUP62,NUSAP1,ODF2,PARD3,PCM1,PDCD10,PEF1,PEX14,PLK4,POLR2M,PPP6R1,RAB15,RAB1A,RAN,SAR1A,SEC24B,SEC24C,STX16,SYT1,TMED2,TRAPPC10,TUBB,UBB,UVRAG,VAMP7,VPS4A |
| GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 287 | 54 | ACTR6,ANP32B,ANP32E,BAZ2A,BRF2,CDT1,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,CREB1,CUL4A,DAXX,DDB1,DMC1,DR1,GRWD1,GTF2H2,GTF3C3,H1-4,H2BC3,H4-16,HAT1,HJURP,HMGB2,HP1BP3,MCM7,MCMDC2,MED6,MIS12,MIS18A,NAP1L1,NAP1L4,PAF1,PSMC2,PSMC3,PSMC4,PSMC6,RAD51,RBBP4,RNF4,RPA2,SART3,SENP6,SET,SPTY2D1,SUPT6H,TBPL2,UBB,UBC |
| GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 116 | 35 | CDK12,FOXC1,HNRNPU,HSPA9,ITCH,KMT2A,N4BP2L2,NFE2L2,NOTCH1,NUDT21,OCIAD1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUS7,PWP1,TCF3,YAP1,YTHDF2 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 1930 | 564 | 77 | ACD,AP2B1,AP3B1,ATAD1,ATM,BAAT,BAG3,BAG4,BAP1,BID,BRCA2,CHMP4B,CSNK2A2,DKC1,DNAJA1,DNM2,FAM53C,FBXO7,GET3,GRPEL1,GRPEL2,GSK3A,HGS,HSPA8,IPO11,IPO7,KPNA2,KPNA4,KPNB1,MAIP1,MAPK8,MED1,MFN2,MTERF4,NUP153,NUP50,NUP62,NXT1,PEX14,PHB2,PML,PMPCB,PPP3CC,PPP3R1,RAB3GAP1,RAN,RBM22,RGPD6,RNF31,RPL21,RPL22,RPS7,SAMM50,SEC61A2,SEC62,SEC63,SFN,SMURF1,SNX16,SPCS2,SRP72,SSR3,TFDP2,TIMM10,TIMM10B,TIMM44,TIMM50,TNPO2,UBB,UBC,UBE2D3,UQCRC2,VAMP7,VPS37A,VPS4A,VTI1A,WASH3P |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 1703 | 152 | AATF,ABL2,ADIPOR1,AIDA,ARRDC3,ATF4,ATM,AXIN1,BANK1,BCL2L12,BCL2L2,BID,BRAP,C3orf33,CACTIN,CD200R1,CDK5RAP3,CGAS,CLASP2,CNOT2,CNOT9,CRTC3,CSNK2A2,CTDSPL2,CUL3,DERL2,DNAJA1,DNM2,DVL3,DYRK2,EDN1,FBXO7,FBXW11,FER,FRZB,GFRAL,GGNBP2,GPATCH3,GSK3A,GTF2H2,HELB,HGS,HIC1,HMGB2,HSF1,ILRUN,IRAK3,ITCH,ITFG2,KLF4,LEMD2,LPXN,LYN,MARCHF7,MBIP,MFN2,MICB,MTMR2,NCOR1,NDUFS3,NFE2L2,NFKB1,NFKBID,NMI,NONO,NOTCH1,NPLOC4,NUP62,OTUD4,OTUD7B,OXR1,PAK1IP1,PARP14,PAWR,PCBP2,PEA15,PFDN5,PHB2,PHIP,PPIF,PPM1A,PPP1R15A,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,RASA2,RC3H1,RIF1,RIOK3,RNF126,SCAI,SH3KBP1,SHLD1,SHLD2,SIRT1,SLC25A5,SLC7A11,SMAD4,SMURF1,SNX5,SOCS6,SOD1,SPART,SPINK5,STAM,STRN3,TAF9B,TCF7L2,TFIP11,THBD,THOC1,THOC5,TICAM1,TNFRSF10A,TRAF2,TRAIP,TRIP12,TSC1,TYRO3,UBB,UBC,UBQLN4,UFD1,USP14,USP47,VDAC2,VPS35,YAP1,YJU2,YTHDF2,YTHDF3,ZC3HC1,ZNF675,ZNRF3 |
| GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 217 | 46 | ATM,BABAM1,BCL2L12,BID,CGAS,CHEK1,CUL4A,DDX11,EEF1E1,EID3,ERCC8,FEM1B,FMR1,FXR1,HELB,HIC1,HNRNPK,HSF1,KMT5A,MARCHF7,NSD2,PML,PPP4C,PPP4R2,RAD51,RAD51AP1,RFWD3,RIF1,RNASEH2B,RPA2,SHLD1,SHLD2,SIRT1,SLF1,SMG1,TAF9B,TERF2IP,TFIP11,THOC1,THOC5,TRIP12,UBQLN4,UIMC1,USP1,USP47,YJU2 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1724 | 152 | ADRM1,AKAP8,AKAP8L,ANKLE2,ANP32B,ARAF,ARRDC3,ATM,ATXN3,AXIN1,BAG2,BAG4,BANK1,BID,BRD4,BRMS1,CASP10,CASP3,CCNB1,CCNK,CCNT1,CCNT2,CDC6,CDK1,CDK5RAP3,CLCF1,CLDN4,CLN6,CNOT9,COA8,COP1,CUL3,DAXX,DCUN1D2,DDA1,DDB1,DTL,DVL3,EDN1,EGLN2,EIF2S3B,EIF3E,EIF5A,FAF1,FANCI,FANCM,FBXW11,FMR1,FXR1,GFRAL,GSK3A,HNRNPK,HNRNPL,HSF1,IQGAP3,ITCH,JTB,KAT5,KAT7,KHDC1L,KLB,KLF4,KMT2A,LYN,MAP2K7,MAP4K4,MAPK8,MARCHF7,MASTL,MECP2,MTCH1,MTPN,NFE2L2,NGRN,NMI,NOTCH1,NSD3,OAZ3,PABPC1,PAF1,PAIP1,PAK1,PAK2,PARP14,PAWR,PDCD10,PEA15,PEF1,PHB2,PHF1,PML,POLDIP3,POMT2,PPP1R15A,PPP2R5D,PSMC1,PSMC2,PSMC4,PSME2,PTPN11,RAB1A,RAB3GAP1,RAP2C,RCHY1,RHBDD3,RICTOR,RIF1,RNF19B,RNF40,RPS6KA5,RPUSD4,SART3,SENP1,SIRT1,SLC11A1,SMAD4,SMURF1,SNW1,SOD1,SPDYA,STK10,SUMO2,TAB2,TADA2B,TCF7L2,TELO2,TERF2IP,TICAM1,TMEM119,TNFRSF10A,TPX2,TRAF2,TRAF4,UBB,UBC,UBE2C,UBE2I,UBE2K,UBE3A,UPF3B,USP16,VPS35,WDR48,XIAP,YES1,YTHDF2,YTHDF3,ZCCHC4,ZEB2,ZFAND2A,ZFP91,ZNF622 |
| GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 322 | 56 | BTK,CACTIN,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,FBXW11,GPATCH3,IRAK3,ITCH,LYN,MATR3,MUC13,NFKB1,NONO,NPLOC4,OTUD4,PAK1,PAK2,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UFD1,XIAP |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1930 | 1781 | 155 | ABL2,ACAP2,ACD,ADRM1,AGAP6,AHSA2P,ANP32B,APH1A,ARHGAP11B,ARHGAP19,ARRDC3,ATF2,AURKB,AXIN1,AZIN1,BID,BNIP2,BTK,CASP10,CASP3,CCNB1,CCNK,CCNT1,CCNT2,CDC6,CDCA5,CDK1,CDT1,CHTF18,CLDN4,CNOT6,CNOT9,COA8,CRTC3,CTBP2,CWF19L1,CYB5B,DAXX,DCP1A,DCUN1D2,DDX11,DENND1B,DEPDC1,DGKZ,DKC1,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC9,DNM2,DOCK2,DVL3,EDN1,EIF3E,FER,FMR1,FOXC1,GALR2,GDI2,GFRAL,GNA13,GSK3A,GTF2F1,GTF2H2,HMGB2,HNRNPL,HNRNPU,HSCB,HSF1,IL18RAP,IQGAP3,IRAK3,JTB,KHDC1L,KLF4,KMT2A,LRRFIP1,LYN,MAP2K7,MAP4K4,MAPK8,MASTL,MED1,MTCH1,MTPN,NAF1,NCAPH,NDEL1,NEK2,NEK7,NFKB1,PABPN1,PAK1,PAK2,PDCD10,PEA15,PHB2,PLAA,PML,PPP1R15A,PPP2CB,PPRC1,PSME2,PTPN11,RAB11FIP2,RAB1A,RAB3GAP1,RACGAP1,RAN,RANGAP1,RASA2,RCC2,RFC1,RGPD6,RICTOR,RNF25,RNF31,RPS6KA5,SENP1,SIRT1,SLC11A1,SOD1,SPDYA,STK10,TAB2,TBC1D15,TBC1D22B,TCF3,TCF7L2,TELO2,TERF2IP,TICAM1,TNFRSF10A,TNKS,TPX2,TRAF2,TRAF4,TRAF5,TRIM23,TSC1,UBA2,UBB,UBC,UBE2C,UBE2I,VAV2,WAPL,WNT9B,XRCC4,ZC3H15,ZEB2,ZFP91,ZNF16,ZNF622 |
| GO_RESPONSE_TO_HEAT | 0.0e+00 | 0.0e+00 | 1930 | 183 | 42 | ATM,ATXN3,BAG1,BAG2,BAG3,BAG4,CAMK2G,CHORDC1,CREBBP,DAXX,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC2,DNAJC7,EIF2B4,HSF1,HSF2,HSP90AA2P,HSP90AA4P,HSP90AB4P,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,LYN,MAP2K7,MICB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PDCL3,RAE1,RPA2,SIRT1,SLU7,SOD1 |
| GO_NCRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 471 | 68 | AARSD1,ADAT2,AGO2,ALKBH1,ALKBH8,C1D,CDKAL1,DDX1,DDX52,DDX54,DIS3,DKC1,DUS3L,EEF1E1,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FCF1,FRG1,GAR1,GRSF1,HSD17B10,INTS7,MRM3,MTERF4,NAF1,NARS1,NFKB1,NOL9,NSA2,NSUN3,PES1,POP7,PUS1,PUS7,QRSL1,RAN,RBM7,RC3H1,RIOK3,RPS7,RPUSD4,RRP1,RRP9,SART1,SBDS,SEPHS1,SRFBP1,SRRT,TENT4A,TEX10,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TSR1,TSR2,TYW3,UTP18,WARS2,WBP11,WDR4,ZBTB8OS,ZCCHC4,ZCCHC8 |
| GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 81 | 29 | AURKB,CCNB1,CDC16,CDC27,CDK1,CDK2,CUL3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,UBB,UBC,UBE2C |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 1335 | 127 | ABITRAM,ABL2,ABRAXAS2,ACTR3,ATXN3,AURKB,BAG4,BAIAP2L1,BIN1,BRCA2,C2CD3,CAMSAP1,CAPN10,CAPN2,CCDC13,CCNB1,CDK1,CDK2,CENPA,CENPW,CEP120,CEP135,CEP57,CEP72,CEP76,CFAP157,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CKAP5,CLASP2,CLTC,CNTROB,CUL3,DIAPH2,DIAPH3,DNAJB6,DOCK2,DRG1,DYNC1LI1,EDN1,EPB41L4A,ESPL1,FER,FGD1,FGFR1OP,FLII,FMNL3,FOPNL,GSK3A,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HDGFL3,HNRNPU,KIAA0753,KIF18A,KIF2C,KNSTRN,KPNB1,KRT16,LCP1,MCIDAS,MCPH1,MECP2,MTPN,NCKAP1,NCOR1,NDEL1,NEK2,NEK7,NSFL1C,NUF2,NUP62,NUSAP1,ODF2,PAK1,PARD3,PAWR,PCM1,PDCL3,PEX14,PHIP,PLK4,PRC1,RACGAP1,RAE1,RAN,RASSF1,RCC1,RICTOR,RND3,RNF4,RSPH4A,RUFY3,SBDS,SENP6,SH3KBP1,SIX4,SLAIN2,SMAD4,SOD1,STAG1,STAG2,STARD9,STRIP1,TNKS,TPX2,TSC1,TTC26,TUBA1C,TUBA8,TUBB,TWF1,UVRAG,VPS4A,WASF2,WASH3P,WASH6P,WASHC1,WDR62,WEE1 |
| GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 177 | 41 | ACD,AKAP8,AKAP8L,ATM,AURKB,BRD4,CCNB1,CDT1,CUL3,DDX11,DKC1,ESPL1,FMR1,GTF2H2,HNRNPA1,HNRNPU,KAT7,KMT2A,MAP2K7,MECP2,MIER1,NAF1,NEK2,NEK7,NSD3,NSMCE2,PAF1,PHF1,PML,RAD21,RIF1,RNF40,RPS6KA5,SART3,SETDB1,SIRT1,SLF1,SMAD4,SNW1,TADA2B,TNKS |
| GO_MRNA_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 151 | 38 | AKAP8L,ALYREF,CASC3,CDC40,CPSF2,EIF5A,FIP1L1,FMR1,HNRNPA1,HNRNPA3,HSF1,MAGOHB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,RAE1,RBM8A,RNPS1,SARNP,SLBP,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,TNKS,UPF3B,ZC3H3 |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 1116 | 113 | ACTR3,AP1G1,BTK,BTN2A1,BTN2A3P,C12orf4,CACTIN,CD200R1,CD226,CD274,CD300LG,CD3G,CFHR2,CGAS,CLCF1,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX1,DDX60,DENND1B,EIF2B4,ELF2,ERAP1,EXOSC3,FBXW11,FER,GPATCH3,HMGB2,IGHV3-43,IGKV1D-33,IL18RAP,IRAK3,ITCH,LPXN,LYN,MAP2K7,MAPK8,MATR3,MED1,MICB,MUC13,NCKAP1,NFKB1,NFKBID,NMI,NONO,NPLOC4,NSD2,OTUD4,PAK1,PAK2,PARP14,PAWR,POLR3C,POLR3F,PPP3R1,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RC3H1,RIF1,RIOK3,RNF31,RPS6KA5,SHLD1,SHLD2,SIRT1,SLC11A1,SPINK5,STOML2,SUPT6H,TAB2,THOC1,TICAM1,TNIP2,TRAF2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,VAV2,WASF2,XIAP,YES1,YTHDF2,YTHDF3 |
| GO_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 83 | 29 | FOXC1,HSPA9,ITCH,KMT2A,N4BP2L2,NFE2L2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUS7,TCF3,YAP1,YTHDF2 |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1930 | 990 | 104 | AP3B1,ATM,ATXN1L,AZI2,BRCA2,BTK,CASP3,CCNB2,CD274,CD3G,CLCF1,CNOT4,CREB1,CREBBP,CUL4A,DCAF1,DOCK2,DPF2,EXOSC3,FBXO7,FOXC1,H4-16,HIPK1,HMGB2,HOXA9,HSPA9,IRAK3,ITCH,ITFG2,JMJD6,KLF4,KMT2A,KMT2B,LYN,MARCHF7,MED1,MELK,N4BP2L2,NCAPH2,NFE2L2,NFKBID,NKAP,NOTCH1,NSD2,NUDT21,PAF1,PKNOX1,PML,POLL,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUS7,RBM15,RC3H1,RIF1,RO60,RPL22,SART1,SART3,SBDS,SENP1,SHLD1,SHLD2,SIRT1,SIX4,SLC25A38,SLC4A1,SLC7A6OS,SOD1,SP3,SPINK5,SUPT6H,TCF3,THOC1,THOC5,TOP2A,TSC1,TYRO3,UNG,WASF2,XRCC4,YAP1,YTHDF2,ZEB1,ZNF16,ZNF675 |
| GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 0.0e+00 | 0.0e+00 | 1930 | 363 | 58 | AFP,ASB3,ASB7,ATG12,BTBD1,COP1,COPS2,COPS3,COPS7B,CUL1,CUL3,CUL4A,DDA1,DDB1,DTL,ERCC8,FBXL3,FBXO11,FBXO2,FBXO30,FBXO6,FBXO7,FBXW11,FBXW2,FEM1B,KBTBD8,KLHL21,LRRC41,NAE1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTP4A2,RAB1A,RAB38,RABGGTB,RNF7,SERPINC1,SOCS6,STT3A,UBE2M,UBXN7 |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 528 | 71 | AIFM2,ATAD3A,ATF2,ATG12,ATP5F1B,ATP5MG,ATP5PB,BAG3,BAG4,BAP1,BID,BLOC1S2,CEP89,CHCHD3,CISD2,COA8,COX19,COX20,CSNK2A2,DMAC2,DNM2,ECSIT,FANCG,FBXO7,GABARAPL1,GRPEL1,GRPEL2,GSK3A,HSD17B10,JTB,MAIP1,MAPK8,MFN2,MTERF4,MTFR2,MYO19,NDUFA10,NDUFA9,NDUFAF6,NDUFS3,NDUFS7,NDUFS8,NRF1,PHB2,PMPCB,PPIF,PPP2CB,PPP3CC,PPP3R1,PPRC1,RAB38,RNF31,SAMM50,SFN,SLC25A33,SLC25A5,SMURF1,STOML2,SUPV3L1,TFDP2,TIMM10,TIMM10B,TIMM44,TIMM50,TMEM11,TOP3A,UBE2D3,UQCRC2,USP30,VDAC1,VPS35 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 895 | 97 | ACTR3,AP1G1,BTK,BTN2A1,BTN2A3P,CACTIN,CD226,CD274,CD3G,CFHR2,CGAS,CLCF1,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX1,DDX60,DENND1B,EIF2B4,ELF2,EXOSC3,FBXW11,GPATCH3,HMGB2,IGHV3-43,IGKV1D-33,IL18RAP,IRAK3,ITCH,LPXN,LYN,MATR3,MED1,MICB,MUC13,NCKAP1,NFKB1,NFKBID,NONO,NPLOC4,NSD2,OTUD4,PAK1,PAK2,PAWR,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RC3H1,RIF1,RIOK3,RNF31,RPS6KA5,SHLD1,SHLD2,SIRT1,SLC11A1,STOML2,TAB2,TICAM1,TNIP2,TRAF2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,VAV2,WASF2,XIAP,YES1 |
| GO_CELLULAR_RESPONSE_TO_HEAT | 0.0e+00 | 0.0e+00 | 1930 | 142 | 36 | ATM,ATXN3,BAG1,BAG2,BAG3,BAG4,CAMK2G,CHORDC1,CREBBP,DAXX,DNAJB1,DNAJB6,DNAJC2,DNAJC7,HSF1,HSF2,HSP90AA2P,HSP90AA4P,HSP90AB4P,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,LYN,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PDCL3,RAE1,RPA2,SIRT1,SLU7 |
| GO_MRNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 0.0e+00 | 1930 | 111 | 32 | AKAP8L,ALYREF,CASC3,CDC40,CPSF2,EIF5A,FIP1L1,MAGOHB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,POLDIP3,RAE1,RBM8A,RNPS1,SARNP,SLBP,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,UPF3B |
| GO_RECOMBINATIONAL_REPAIR | 0.0e+00 | 0.0e+00 | 1930 | 136 | 35 | AP5Z1,ATM,BRCA2,CGAS,CHEK1,DMC1,GINS4,HELB,HUS1B,MCM7,MCMDC2,MMS22L,MUS81,NSMCE2,NUCKS1,POLL,PPP4C,PPP4R2,RAD51,RAD51AP1,RAD54L,RBBP8,RECQL,RECQL4,RFWD3,RIF1,RNF138,RPA2,RPA4,SHLD1,SHLD2,TERF2IP,UBQLN4,WDR48,YY1 |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1859 | 155 | AARSD1,AATF,ABCA1,ABCF1,ABHD17B,ABHD3,ACER1,AGO2,ALG13,ALG5,ALKBH1,ATF4,ATG12,ATP5F1B,ATP5MG,ATP5PB,AZIN1,BANK1,BCAN,CAPN2,CASC3,CDADC1,CDKAL1,CELF1,CHST3,CLTC,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,CSNK2A2,CTPS1,CYC1,DCK,DCTD,DDX1,DENR,DHDDS,DOLPP1,DPH2,DPH5,DPH7,DRG1,EEF1B2,EEF1E1,EIF1AD,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF4B,EIF4G2,EIF5,EIF5A,FMR1,FXR1,GLUD1,GMPS,GSPT1,HNRNPK,HNRNPL,HSPA14,IBA57,IGHMBP2,ILF3,KBTBD8,KLF4,LTO1,MOCOS,MPDU1,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTHFD1,MTIF2,MTPN,MTRF1L,MUC13,NAPRT,NARS1,NAXD,NFE2L2,NFKB1,NGRN,NME6,NMI,NSUN3,OAZ3,OGFOD1,PABPC1,PAIP1,PAPSS2,PATL2,PAWR,PGAP2,POFUT2,POLDIP3,POMT2,PPCDC,PPM1A,PPP1R15A,PTS,PUM1,PUM2,PUS7,QRSL1,RAB38,RAB3GAP1,RBM4B,RBM8A,RC3H1,RPL21,RPL22,RPS7,RPUSD4,SARNP,SEPHS1,SLC22A13,SLC25A38,SLC7A11,ST8SIA4,ST8SIA5,STOML2,STT3A,TACO1,TCF7L2,TET3,TICAM1,TSC1,TYW3,UGDH,UPF3B,USP16,VAPA,VPS35,WARS2,YTHDF2,YTHDF3,ZC3H15,ZCCHC4,ZDHHC18 |
| GO_NCRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 378 | 58 | ADAT2,AGO2,ALKBH1,ALKBH8,C1D,CDKAL1,DDX1,DDX52,DDX54,DIS3,DKC1,DUS3L,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FCF1,FRG1,GAR1,GRSF1,HSD17B10,INTS7,MRM3,MTERF4,NAF1,NOL9,NSA2,NSUN3,PES1,POP7,PUS1,PUS7,RIOK3,RPS7,RPUSD4,RRP1,RRP9,SART1,SBDS,SEPHS1,SRFBP1,SRRT,TENT4A,TEX10,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TSR1,TSR2,TYW3,UTP18,WBP11,WDR4,ZBTB8OS,ZCCHC4 |
| GO_REGULATION_OF_RNA_SPLICING | 0.0e+00 | 0.0e+00 | 1930 | 138 | 35 | C9orf78,CDK12,CELF1,CLK1,CLK3,CWC22,DAZAP1,FMR1,FXR1,HNRNPA1,HNRNPH1,HNRNPK,HNRNPL,HNRNPU,JMJD6,NSRP1,PQBP1,RBM10,RBM15,RBM17,RBM22,RBM25,RBM42,RBM4B,RBM7,RBM8A,RBMX,RNPS1,SART3,SMU1,SNW1,SREK1,SRPK1,SRSF4,ZNF326 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1146 | 112 | AARSD1,ABCF1,ACER1,AGO2,ALKBH1,APH1A,ATF4,BAAT,BANK1,BIN1,CASC3,CASP3,CDKAL1,CELF1,CLN6,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,DDX1,DENR,DPH2,DPH5,DPH7,DRG1,EEF1B2,EEF1E1,EIF1AD,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF4B,EIF4G2,EIF5,EIF5A,ERAP1,ERO1B,FMR1,FXR1,GALC,GLA,GSK3A,GSPT1,GSR,HNRNPL,HSPA14,IGHMBP2,ILF3,KBTBD8,LTO1,LVRN,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTHFD1,MTIF2,MTPN,MTRF1L,NARS1,NFE2L2,NGRN,NPEPPSP1,NSUN3,OGFOD1,PABPC1,PAIP1,PATL2,POLDIP3,PPP1R15A,PUM1,PUM2,PUS7,QRSL1,RBM4B,RBM8A,RC3H1,RPL21,RPL22,RPS7,RPUSD4,SARNP,SEC11A,SLC25A32,SLC7A11,SOD1,SPCS2,ST8SIA4,TACO1,TSC1,UPF3B,USP16,VNN3,WARS2,YTHDF2,YTHDF3,ZC3H15,ZCCHC4 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1930 | 1029 | 104 | ACTL6A,ALKBH1,ANKRD11,ATM,BRCA2,C2CD3,CAPN2,CASP3,CCNB1,CCNB1IP1,CCNB2,CDK1,CELF1,CIR1,CLASP2,CNOT2,CNOT3,COPS2,COPS3,CREBBP,CUL3,CUL4A,DNAJB6,DVL3,E4F1,EDN1,ELF5,ELL,FOXC1,FRZB,GGNBP2,GINS4,GNA13,GRSF1,HINFP,HIPK1,HOXA11,HOXA9,HOXC11,HOXC9,HSF1,INPP5B,KBTBD8,KDM6A,KDM6B,KLF4,KMT2A,LAMA2,MAFG,MED1,MFN2,MTHFD1,NDEL1,NEK2,NFE2L2,NOTCH1,NR2C2,OTUD7B,PAF1,PEF1,PLK4,POFUT2,POLE,PSMC3,PSMC4,RAB14,RACGAP1,RBBP6,RBBP8,RICTOR,RNASEH2B,RPS7,SBDS,SEC24B,SEC24C,SIX4,SMAD4,SMG9,SOD1,SP3,SSR2,SUPT20H,SUPT6H,SYF2,TBR1,TBX3,TET3,THOC5,TMED2,TOP2A,TRIP12,TSC1,UBE2A,UGDH,WDR48,WNT9B,XAB2,YAP1,YTHDF2,ZEB1,ZEB2,ZFAND5,ZNF335,ZNF568 |
| GO_INTERLEUKIN_1_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 100 | 30 | CUL1,FBXW11,IRAK3,NFKB1,OTUD4,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RPS6KA5,TAB2,TNIP2,UBB,UBC,ZNF675 |
| GO_DNA_PACKAGING | 0.0e+00 | 0.0e+00 | 1930 | 210 | 42 | AKAP8,AKAP8L,ANP32B,CCNB1,CDCA5,CDK1,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,DAXX,DFFB,GRWD1,H1-4,H2BC3,H4-16,HAT1,HJURP,HMGB2,HP1BP3,MCPH1,MIS18A,NAP1L1,NAP1L4,NCAPH,NCAPH2,NUSAP1,PAF1,PHF13,RBBP4,SART3,SET,SMC4,SPTY2D1,SRPK1,TENT4A,TOP2A,WAPL |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1187 | 113 | ACTR3,AP1G1,AP3B1,ATXN1L,BTK,BTN2A1,BTN2A3P,C12orf4,CACTIN,CD226,CD274,CD3G,CFHR2,CGAS,CLCF1,CLEC4A,CNPY3,CREB1,CREBBP,CTSL,CUL1,DDX1,DDX60,DENND1B,EDN1,EIF2B4,ELF2,EXOSC3,FBXW11,FER,FOXC1,GPATCH3,HMGB2,HSPH1,IGHV3-43,IGKV1D-33,IL18RAP,IRAK3,ITCH,LPXN,LYN,MATR3,MED1,MICB,MUC13,N4BP2L2,NCKAP1,NFKB1,NFKBID,NKAP,NONO,NPLOC4,NSD2,NUDT21,OTUD4,PAK1,PAK2,PAWR,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RC3H1,RIF1,RIOK3,RNF31,RPS6KA5,SART1,SH3KBP1,SHLD1,SHLD2,SIRT1,SLC11A1,STOML2,TAB2,TICAM1,TNIP2,TRAF2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,VAV2,WASF2,XIAP,YES1,ZNF16,ZNF335 |
| GO_AMIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 876 | 93 | AARSD1,ABCF1,AGO2,ALKBH1,ATF4,BANK1,CASC3,CDKAL1,CELF1,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,DDX1,DENR,DPH2,DPH5,DPH7,DRG1,EEF1B2,EEF1E1,EIF1AD,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF4B,EIF4G2,EIF5,EIF5A,FMR1,FXR1,GSPT1,HNRNPL,HSPA14,IGHMBP2,ILF3,KBTBD8,LTO1,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTHFD1,MTIF2,MTPN,MTRF1L,NARS1,NFE2L2,NGRN,NSUN3,OGFOD1,PABPC1,PAIP1,PATL2,POLDIP3,PPP1R15A,PUM1,PUM2,PUS7,QRSL1,RBM4B,RBM8A,RC3H1,RPL21,RPL22,RPS7,RPUSD4,SARNP,SLC7A11,ST8SIA4,TACO1,TSC1,UPF3B,USP16,WARS2,YTHDF2,YTHDF3,ZC3H15,ZCCHC4 |
| GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1930 | 267 | 47 | ATM,AURKB,BCL2L12,BRCA2,CCNB1,CDC25C,CDK1,CDK2,CDK5RAP3,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CSNK2A2,DYRK2,EEF1E1,HIC1,HINT1,HIPK1,HNRNPK,KAT5,KMT5A,MARCHF7,MDM4,PAK1IP1,PML,PRKAB1,RAD1,RBBP4,RBBP8,RPA2,RPS7,SFN,SIRT1,SNW1,TAF2,TAF9B,TFDP2,TOP3A,TOPBP1,TPX2,UBB,YJU2 |
| GO_RIBOSOME_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1930 | 290 | 49 | AATF,BRIX1,C1D,CUL4A,DDX52,DDX54,DIS3,DKC1,EIF2A,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FCF1,FRG1,GAR1,LTO1,MRM3,MRPS2,MTERF4,NAF1,NIP7,NOL9,NSA2,NSUN3,PAK1IP1,PES1,POP7,PPAN,PWP1,RAN,RIOK3,RPS7,RRP1,RRP9,SART1,SBDS,SRFBP1,TEX10,THUMPD1,TSC1,TSR1,TSR2,URB2,UTP18,WBP11,ZCCHC4,ZNF622 |
| GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1930 | 376 | 56 | ACTL6A,ALKBH1,ANKRD11,BRCA2,C2CD3,CAPN2,CCNB1,CCNB1IP1,CCNB2,CIR1,CNOT2,CNOT3,COPS2,COPS3,CUL3,CUL4A,DNAJB6,EDN1,ELL,FOXC1,GGNBP2,GINS4,GNA13,HINFP,HSF1,INPP5B,KDM6A,MAFG,MED1,MFN2,NDEL1,NEK2,NOTCH1,OTUD7B,PLK4,PSMC3,PSMC4,RBBP6,RBBP8,RNASEH2B,SBDS,SEC24C,SMAD4,SMG9,SP3,SSR2,SUPT6H,SYF2,TBX3,TMED2,UBE2A,WNT9B,XAB2,ZFAND5,ZNF335,ZNF568 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 208 | 41 | AGO2,ATM,CASC3,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CSDE1,DCP1A,DCP2,DHX34,DIS3,EIF3E,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,GSPT1,MAGOHB,MTPAP,NT5C3B,PABPC1,PATL2,PRPF18,RBM8A,RC3H1,RNPS1,RPL21,RPL22,RPS7,SMG1,SMG5,SMG7,SMG8,SMG9,TENT4A,UPF3B |
| GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 133 | 33 | BRCA2,C2CD3,CDK1,CDK2,CEP120,CEP135,CEP72,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP5,CLASP2,CNTROB,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,KIAA0753,MCIDAS,MCPH1,NDEL1,NEK2,NSFL1C,NUP62,ODF2,PCM1,PLK4,UVRAG,WDR62 |
| GO_RESPONSE_TO_RADIATION | 0.0e+00 | 0.0e+00 | 1930 | 441 | 61 | AIPL1,ATF4,ATM,AURKB,BABAM1,BRCA2,CASP3,CDC25A,CHEK1,COP1,COPS3,CREB1,CREBBP,DDB1,DNM2,DTL,ELK1,ERCC8,FANCG,FBXL3,FMR1,GNB1,GRK7,GTF2H2,HSF1,INIP,INTS7,KAT5,LZIC,MAP2K7,MAPK8,MBD4,MECP2,NUCKS1,PER3,PML,POLK,RAD1,RAD18,RAD51,RAD51AP1,RAD54L,RBM4B,RFWD3,RO60,RRH,RRM1,SDE2,SIK1,SIRT1,SLC7A11,THBD,TLK2,TOPBP1,UBE2A,UIMC1,USP1,USP47,XRCC4,YAP1,YY1 |
| GO_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 674 | 78 | ACTR3,BTK,BTN2A1,BTN2A3P,CACTIN,CD200R1,CD226,CD3G,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,DENND1B,EIF2B4,ELF2,FBXW11,FER,GPATCH3,IGHV3-43,IGKV1D-33,IRAK3,ITCH,LPXN,LYN,MAP2K7,MAPK8,MICB,MUC13,NCKAP1,NFKB1,NFKBID,NPLOC4,OTUD4,PAK1,PAK2,PAWR,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RC3H1,RIOK3,RNF31,RPS6KA5,STOML2,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UFD1,VAV2,WASF2,XIAP,YES1 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | 0.0e+00 | 0.0e+00 | 1930 | 190 | 39 | AP1G1,AP2B1,CLEC4A,CLTA,CLTC,CTSL,DCTN4,DCTN5,DCTN6,DNM2,DYNC1LI1,ERAP1,KIF18A,KIF2C,MICB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RACGAP1,SEC24B,SEC24C,SLC11A1,TAP2 |
| GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 514 | 66 | AP1G1,BTK,CACTIN,CD226,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,FBXW11,GPATCH3,HMGB2,IL18RAP,IRAK3,ITCH,LYN,MATR3,MED1,MUC13,NFKB1,NONO,NPLOC4,OTUD4,PAK1,PAK2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,SUCNR1,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,XIAP |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1823 | 148 | AIDA,AKAP8,AKAP8L,ANKLE2,ARAF,ATM,AXIN1,BAG4,BANK1,BRD4,BTBD10,C3orf33,CACTIN,CAPN2,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CD2BP2,CDC25A,CDC25C,CDC6,CDK1,CDK12,CDK5RAP3,CHORDC1,CLCF1,CNOT9,DAXX,DBNDD2,DGKZ,DNAJA1,DVL3,EDN1,ELL,FAF1,FBXO7,FER,FGFR1OP,FMR1,FXR1,GFRAL,GGNBP2,GSK3A,HGS,HNRNPU,HSF1,IBTK,IPO7,IQGAP3,IRAK3,ITCH,JTB,KLB,KLF4,LEMD2,LYN,MAP2K7,MAP4K4,MASTL,MBIP,MCM7,MCPH1,MTMR2,NCOR1,NOTCH1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PAK1,PAK2,PARD3,PARP14,PCDH11X,PDCD10,PDCL3,PEA15,PFKFB3,PHB2,PHIP,PML,PPIF,PPIL4,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R1B,PPP2R5D,PPP2R5E,PPP4R2,PPP6R1,PRKRIP1,PTPN11,PWP1,RAB38,RAD51,RAE1,RAP2C,RBM26,RICTOR,RPS6KA5,SET,SFN,SIRT1,SLC11A1,SLC25A33,SMAD4,SMG5,SMG7,SMG8,SOCS6,SOD1,SPDYA,SRPX2,STK10,STOML2,TAB2,TELO2,TERF2IP,TMEM119,TNFRSF10A,TPX2,TRAF2,TRAF4,TSC1,TWF1,UBB,UBC,UBE2K,UVRAG,VAV2,WASHC1,WNT9B,YES1,ZEB2,ZFP91,ZNF16,ZNF622,ZNF675 |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1930 | 1427 | 125 | AATF,ABL2,ADIPOR1,AIDA,ARRDC3,ATAD1,ATM,AXIN1,BANK1,BCL2L12,BCL2L2,BID,BRAP,C3orf33,CACTIN,CDK5RAP3,CNOT2,CNOT9,CRTC3,CSNK2A2,CTDSPL2,CUL3,DNAJA1,DNM2,DVL3,DYRK2,EDN1,FBXW11,FMR1,FRZB,GFRAL,GGNBP2,GPATCH3,GSK3A,GTF2H2,HGS,HIC1,HMGB2,IRAK3,ITCH,ITFG2,KLF4,LEMD2,LPXN,LYN,MARCHF7,MBIP,MFN2,MTMR2,NCOR1,NDUFS3,NFE2L2,NFKBID,NONO,NOTCH1,NPLOC4,NUP62,OR56A4,OTUD4,OTUD7B,PAK1IP1,PARP14,PAWR,PEA15,PFDN5,PHB2,PHIP,PPIF,PPM1A,PPP1R15A,PPP2CB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,RASA2,RIOK3,RNF126,SCAI,SH3KBP1,SIRT1,SLC25A5,SMAD4,SMURF1,SNX5,SOCS6,SPART,STAM,STRN3,TAF9B,TCF7L2,TICAM1,TNFRSF10A,TRAF2,TRAIP,TSC1,TYRO3,UBB,UBC,UFD1,USP47,VDAC2,YAP1,YJU2,YTHDF2,YTHDF3,ZC3HC1,ZNF675,ZNRF3 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 804 | 86 | AP1G1,ATM,BAP1,BRD4,BTK,CACTIN,CD200R1,CD226,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,ERAP1,FBXW11,GPATCH3,HMGB2,IL18RAP,ILRUN,IRAK3,ITCH,KLF4,LYN,MATR3,MCPH1,MED1,MICB,MUC13,NFKB1,NMI,NONO,NPLOC4,OTUD4,PAK1,PAK2,PARP14,PCBP2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RHBDD3,RICTOR,RIOK3,RPS6KA5,SOD1,SPINK5,SUCNR1,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,VPS35,XIAP,YTHDF2,YTHDF3 |
| GO_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1930 | 1457 | 126 | ACTR3,AFP,AGO2,ALKBH1,ANKRD49,ATM,BCL2L2,BRCA2,BUB1,CAPN2,CASP3,CCNB1,CCNB1IP1,CDC25A,CDC25C,CDK1,CDK2,CELF1,CEP57,CFAP157,CIP2A,CLDN4,CNOT9,CSDE1,CSNK2A2,DAZAP1,DIAPH2,DMC1,DNAJA1,DNAJB6,DNM2,EDN1,EIF2B4,ESPL1,FANCG,FANCM,FEM1B,FOXC1,GGNBP2,GNRH1,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,HUS1B,ICA1L,INPP5B,KIF18A,KLHDC3,KMT2B,LHFPL2,LIN9,MASTL,MCMDC2,MED1,MND1,MNS1,MSH4,MUS81,NCAPH,NCAPH2,NEK2,NLRP14,NOTCH1,NR2C2,NUF2,NUP62,OAZ3,ODF2,PHB2,PLK4,PSMC3IP,PTPN11,PUM1,RACGAP1,RAD1,RAD21,RAD51,RAD54L,RAI14,RBBP8,RBM15,RBM7,RNF38,RRM1,SF1,SIRT1,SIX4,SLC26A8,SMAD4,SMC1B,SMC4,SNRPA1,SOD1,SORD,SOX15,SP3,SPDYA,SRPK1,STAG2,TBX3,THBD,TIAL1,TMED2,TMEM119,TOP2A,TOP3A,TTC26,TYRO3,UBB,UBE2A,UBE3A,UBXN8,VDAC2,WAPL,WDR48,WNT9B,YTHDF2,YY1,ZFP42,ZNF148,ZNF296,ZNF568 |
| GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 484 | 63 | AGO2,ALKBH1,ATF4,BANK1,BIN1,CASC3,CASP3,CELF1,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,CPEB1,DDX1,DPH2,DPH5,DPH7,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3H,EIF4B,EIF4G2,EIF5,EIF5A,FMR1,FXR1,GSK3A,GSPT1,HNRNPL,ILF3,KBTBD8,MTIF2,MTPN,NFE2L2,NGRN,NSUN3,OGFOD1,PABPC1,PAIP1,PATL2,POLDIP3,PPP1R15A,PUM1,PUM2,PUS7,RBM4B,RBM8A,RC3H1,RPL22,RPUSD4,SARNP,SLC7A11,TACO1,TSC1,UPF3B,USP16,YTHDF2,YTHDF3,ZCCHC4 |
| GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 115 | 30 | CLEC4A,CREBBP,CUL1,FBXW11,LYN,MUC13,NFKB1,PAK1,PAK2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RPS6KA5,TAB2 |
| GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_HYPOXIA | 0.0e+00 | 0.0e+00 | 1930 | 77 | 25 | CREBBP,EGLN2,NFE2L2,NOTCH1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,UBB,UBC |
| GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1930 | 125 | 31 | ATF4,BAG3,CHEK1,CREBBP,DNAJB1,EGLN2,HSF1,HSF2,NFE2L2,NOTCH1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,UBB,UBC |
| GO_MEIOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 245 | 43 | ACTR3,ATM,BRCA2,BUB1,CCNB1IP1,CDC25A,CDC25C,CDK2,DMC1,ESPL1,FANCM,HSF1,HUS1B,KIF18A,KLHDC3,MASTL,MCMDC2,MND1,MNS1,MSH4,MUS81,NCAPH,NCAPH2,NEK2,NUF2,PSMC3IP,RAD1,RAD21,RAD51,RAD54L,RBBP8,RBM7,SLC26A8,SMC1B,SMC4,SPDYA,STAG2,TOP2A,TOP3A,UBB,WAPL,YTHDF2,ZFP42 |
| GO_RNA_POLYADENYLATION | 0.0e+00 | 0.0e+00 | 1930 | 46 | 20 | CCNT1,CPEB1,CPSF2,CPSF6,CPSF7,FIP1L1,GRSF1,HSF1,MTPAP,NUDT21,PABPC1,PAF1,PAPOLA,RNF40,SCAF8,SNRPA,TENT4A,VIRMA,ZC3H14,ZC3H3 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 603 | 71 | AATF,ATF4,ATM,BAG3,BCL2L12,BCL2L2,BID,BLOC1S2,BRCA2,BTK,CASP10,CASP3,COA8,CSNK2A2,CUL1,CUL3,CUL4A,DAXX,DIDO1,DNAJA1,DPF2,DYRK2,FAF1,FEM1B,GFRAL,GSK3A,HIC1,HINT1,HIPK1,HMGB2,HNRNPK,MAPK8,MARCHF7,MELK,NDUFS3,NFE2L2,NONO,PAK2,PARP2,PAWR,PDCD10,PEA15,PHIP,PLAGL2,PML,PPIF,PPP1R15A,PPP2R1B,PPP3CC,PPP3R1,RPS7,SENP1,SFN,SIRT1,SLC25A5,SNW1,SOD1,TAF9B,TCF7L2,TFDP2,TICAM1,TIMM50,TNFRSF10A,TRAF2,UBB,UBE2K,USP47,VDAC2,YAP1,ZC3HC1,ZNF622 |
| GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | 0.0e+00 | 0.0e+00 | 1930 | 102 | 28 | C9orf78,CELF1,CWC22,DAZAP1,FMR1,FXR1,HNRNPA1,HNRNPK,HNRNPL,HNRNPU,JMJD6,NSRP1,RBM10,RBM15,RBM17,RBM25,RBM42,RBM4B,RBM7,RBM8A,RBMX,RNPS1,SART3,SMU1,SNW1,SREK1,SRPK1,SRSF4 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 0.0e+00 | 0.0e+00 | 1930 | 649 | 74 | ACTL6A,ALKBH1,ANKRD11,ATM,BRCA2,C2CD3,CAPN2,CASP3,CCNB1,CCNB1IP1,CCNB2,CELF1,CIR1,CNOT2,CNOT3,COPS2,COPS3,CUL3,CUL4A,DNAJB6,DVL3,EDN1,ELL,FOXC1,GGNBP2,GINS4,GNA13,HINFP,HOXA11,HOXA9,HOXC11,HOXC9,HSF1,INPP5B,KBTBD8,KDM6A,MAFG,MED1,MFN2,MTHFD1,NDEL1,NEK2,NOTCH1,OTUD7B,PEF1,PLK4,PSMC3,PSMC4,RBBP6,RBBP8,RICTOR,RNASEH2B,RPS7,SBDS,SEC24B,SEC24C,SIX4,SMAD4,SMG9,SP3,SSR2,SUPT6H,SYF2,TBX3,TMED2,TSC1,UBE2A,WNT9B,XAB2,ZEB1,ZEB2,ZFAND5,ZNF335,ZNF568 |
| GO_MITOTIC_CELL_CYCLE_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1930 | 165 | 35 | ATF2,ATM,AURKB,BUB1,CCNB1,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CDT1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,DYNC1LI1,HUS1B,MDM4,MUS81,NAE1,PML,PRCC,PSMG2,RFWD3,RPA2,SFN,SYF2,TFDP2,TOP2A,TOPBP1,VPS4A,WEE1 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION | 0.0e+00 | 0.0e+00 | 1930 | 227 | 41 | AP1G1,AP2B1,AP3B1,CLEC4A,CLTA,CLTC,CTSL,DCTN4,DCTN5,DCTN6,DNM2,DYNC1LI1,ERAP1,KIF18A,KIF2C,MICB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAB35,RACGAP1,SEC24B,SEC24C,SLC11A1,TAP2 |
| GO_MACROMOLECULE_METHYLATION | 0.0e+00 | 0.0e+00 | 1930 | 306 | 48 | ALKBH8,BAZ2A,BRD4,CBLL1,DOT1L,EEF1AKMT2,EZH1,FBXO11,GSK3A,GSPT1,H1-4,HSD17B10,KDM6A,KMT2A,KMT2B,KMT5A,MECP2,METTL21A,METTL4,MIS18A,MRM3,MTERF4,NSD2,NSD3,NSUN3,PAF1,PHF1,PRDM4,PWP1,RBM15,RIF1,SETD4,SETDB1,SIRT1,SMAD4,SNRPB,SNW1,SUPT6H,TET3,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,VIRMA,WDR4,ZCCHC4,ZNF335 |
| GO_REGULATION_OF_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 103 | 28 | ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDCA5,CDT1,CSNK2A2,CUL3,DDX11,DYNC1LI1,ESPL1,HNRNPU,KIF2C,KNSTRN,NEK2,NSMCE2,PSMG2,PUM1,PUM2,RACGAP1,RAD18,RAD21,RCC2,SLF1,TNKS,WAPL |
| GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 95 | 27 | CUL1,CUL4A,DMAC2,FBXL3,FBXO2,FBXO6,FBXW11,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RNF7 |
| GO_RESPONSE_TO_TEMPERATURE_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 249 | 43 | ATM,ATXN3,BAG1,BAG2,BAG3,BAG4,CAMK2G,CHORDC1,CREBBP,DAXX,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC2,DNAJC7,EIF2B4,HSF1,HSF2,HSP90AA2P,HSP90AA4P,HSP90AB4P,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,LYN,MAP2K7,MICB,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PDCL3,RAE1,RPA2,SIRT1,SLU7,SOD1,UCP3 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1930 | 942 | 93 | ABCA1,ABITRAM,ACTR3,AIDA,ATM,ATMIN,ATXN2L,BAG4,BAIAP2L1,BID,BIN1,CAMSAP1,CDKL1,CDT1,CEP120,CEP135,CEP76,CHMP4B,CHMP5,CLASP2,CNOT2,CNOT6,CNOT6L,CNTROB,CREB1,CUL4A,DDB1,DNAJB1,DNAJB6,DNM2,DR1,DRG1,EDN1,FAF1,FER,FMR1,FXR1,GTF2H2,HGS,HJURP,HNRNPU,HSF1,HSPA8,LCP1,LRRTM2,MAP4K4,MECP2,MNS1,MTPN,NCKAP1,NDEL1,NOTCH1,NUP62,PAK1,PATL2,PEX14,PLK4,PPM1A,PSMC2,PSMC3,PSMC4,PSMC6,PTPN11,RAB3GAP1,RCC2,RICTOR,RIOK3,RNF4,RPA2,SAR1A,SENP6,SIX4,SLAIN2,SLF1,SMAD4,SPTY2D1,SRPX2,STAG1,STAG2,STAM,STX18,TCHP,TFIP11,TICAM1,TSC1,TWF1,VDAC2,VPS35,VPS4A,WASF2,WASH3P,WASH6P,WASHC1 |
| GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | 0.0e+00 | 0.0e+00 | 1930 | 297 | 47 | AGO2,APTX,CASP3,CNOT2,CNOT6,CNOT6L,CPSF2,CPSF6,CPSF7,CUL4A,DCP1A,DCP2,DDB1,DDX1,DFFB,DIS3,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FANCM,FIP1L1,GTF2H2,HMCES,HMGB2,HSF1,KPNB1,MUS81,NOL9,NUDT21,POLE,POLK,POP7,RAD1,RBBP8,REXO2,RFC1,RNASEH2A,RNASEH2B,RPA2,TATDN2,TDP2,UBB,UBC,ZC3H12C |
| GO_REGULATION_OF_NUCLEAR_DIVISION | 0.0e+00 | 0.0e+00 | 1930 | 187 | 37 | ATM,AURKB,BUB1,CCNB1,CDC25C,CDC27,CDC6,CDCA5,CDT1,CHEK1,CHMP4B,CHMP5,CUL3,DRG1,DYNC1LI1,EDN1,ESPL1,HNRNPU,MTBP,NEK2,NME6,NSFL1C,NSMCE2,NUP62,NUSAP1,PHB2,PHIP,PSMG2,RAD1,RAD21,RCC1,SH2B1,SLF1,STAG1,STAG2,TNKS,UBE2C |
| GO_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 286 | 46 | AKAP8L,ALYREF,AP2B1,ATAD1,ATM,CASC3,CDC40,CEP72,CPSF2,DNM2,EIF5A,FIP1L1,HNRNPU,KLHL21,MAGOHB,NSG1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,NXT1,PABPN1,PCM1,POLDIP3,RAE1,RAN,RBM8A,RCC2,RNPS1,SARNP,SLBP,SLU7,SMG1,SMG5,SMG7,SRSF11,SRSF4,SUPT6H,THOC1,THOC5,TSC1,TTC26,UPF3B,VPS35 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1930 | 1869 | 147 | ADIPOR1,ATM,AXIN1,BAG4,BANK1,BID,BRD4,CAPN10,CASP10,CD226,CD3G,CDK1,CDK5RAP3,CDKN2AIP,CGAS,CHERP,CLCF1,CNOT9,COA8,CREB1,CREBBP,CRLF3,CSNK1G1,CTBP2,DAXX,DDX1,DDX60,DVL3,EDN1,EEF1E1,EIF2A,FAF1,FGF22,FMR1,GFRAL,GID8,GLUD1,GPR89A,GSK3A,HIC1,HINT1,HSF1,IQGAP3,ITPR3,ITSN2,KLB,LAMA2,LANCL2,LRRTM2,LYN,MAP2K7,MAP4K4,MAPK8,MECP2,MED1,MIER1,NEPRO,NFKB1,NOTCH1,NOTCH2NLA,NSG1,NUCKS1,NUP62,PAK1,PAK2,PARP14,PDCD10,PDCL,PEA15,PHB2,PHIP,PLAGL2,PML,PPIF,PPM1A,PPP2R1B,PPP3CC,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PTPN23,PUM1,PUM2,RAB3GAP1,RC3H1,REL,RICTOR,RNF31,RPS7,RUSC1,SFN,SH2B1,SIRT1,SLC38A9,SMAD4,SNW1,SOD1,STAM,STK19,SYT1,TAB2,TCF7L2,TEDC1,TELO2,TERF2IP,TFDP2,TICAM1,TMEM108,TNFRSF10A,TNIP2,TNKS,TRAF2,TRAF4,TRAF5,UBB,UBC,UBE2I,UBE2K,UBE3A,USP47,VAMP7,VAPA,VPS35,XIAP,YAP1,ZC3H3,ZEB2,ZFP91,ZNF622 |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 1567 | 130 | ABCA1,ACTR3,AKAP8,ANKHD1,AP1G1,BAIAP2L1,BANK1,BTK,CA3,CACTIN,CAMK2G,CAPN2,CASP3,CD226,CD274,CGAS,CHMP5,CLEC4A,CNPY3,CRCP,CREBBP,CREBZF,CTSL,CUL1,DDX1,DDX60,ECSIT,EDN1,ERAP1,EXOSC4,EXOSC5,FBXW11,FER,FMR1,GNRH1,GPATCH3,GTF2F1,HMGB2,HMGN2,HNRNPUL1,HSF1,IGHV3-43,IL18RAP,ILF3,ILRUN,IPO7,IRAK3,ITCH,KRT16,LGALS8,LYN,LYZ,MAPK8,MATR3,MED1,MICB,MUC13,MUS81,NFKB1,NFKBIB,NMI,NONO,NOTCH1,NPLOC4,NT5C3A,OCIAD2,OTUD4,PABPN1,PAF1,PAK1,PAK2,PARP14,PCBP2,PLAA,PML,POLR3C,POLR3E,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RAB14,RAB1A,RIOK3,RPS6KA5,SLC11A1,SPINK5,SRPK1,ST13,TAB2,THBD,TICAM1,TNIP2,TRIM23,TRIM56,TUBB,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,USP14,VAMP7,XIAP,YAP1,YTHDF2,YTHDF3,ZC3HAV1 |
| GO_ACTIVATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 720 | 78 | ACTR3,BTK,BTN2A1,BTN2A3P,CACTIN,CD226,CD3G,CFHR2,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,DENND1B,EIF2B4,ELF2,FBXW11,GPATCH3,IGHV3-43,IGKV1D-33,IRAK3,ITCH,LPXN,LYN,MATR3,MICB,MUC13,NCKAP1,NFKB1,NFKBID,NONO,NPLOC4,OTUD4,PAK1,PAK2,PAWR,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RC3H1,RIOK3,RNF31,RPS6KA5,STOML2,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UFD1,VAV2,WASF2,XIAP,YES1 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1930 | 1863 | 146 | ABCA1,ABL2,ADIPOR1,AIDA,ARAF,ARFGEF2,ARHGAP11B,ARHGAP19,ARHGEF38,ARRDC3,ATM,AURKB,AXIN1,BAG4,BANK1,BCL2L12,BCL2L2,BID,BRD4,C3orf33,CASP10,CDK1,CDK12,CDK2,CDK5RAP3,CEP55,CGAS,CHEK1,CHERP,CRTC3,CSNK2A2,CUL3,DAXX,DDX1,DDX60,DNAJA1,DNM2,DVL3,DYRK2,EDN1,EEF1E1,FBXW11,FGD1,FGF22,GDI2,GFRAL,GNA13,GPATCH3,GPR89A,GSK3A,HGS,HIC1,HINT1,HIPK1,HNRNPK,INPP5B,IQGAP3,IRAK3,ITCH,ITFG2,ITSN2,KAT5,KLB,KLF4,KMT5A,LEMD2,LYN,MAP2K7,MAP4K4,MARCHF7,MBIP,MDM4,MFN2,MIER1,NCOR1,NDUFS3,NFE2L2,NFKBID,NONO,NOTCH1,NPLOC4,NUP62,OTUD7B,PAK1,PAK1IP1,PDCD10,PEA15,PHB2,PLAGL2,PML,PPIF,PPM1A,PPP2CB,PRKAB1,PTPN11,PUM1,PUM2,RACGAP1,RAD1,RASA2,RBBP4,RBBP8,RC3H1,REL,RICTOR,RIOK3,RNF31,RPA2,RPS7,SCAI,SIRT1,SLC38A9,SMAD4,SOD1,STK19,TAB2,TAF2,TAF9B,TCF7L2,TELO2,TERF2IP,TICAM1,TNFRSF10A,TNIP2,TOP3A,TOPBP1,TPX2,TRAF2,TRAF4,TRAF5,TSC1,UBB,UBC,UBE2I,UBE3A,UFD1,USP47,VAPA,VAV2,VDAC2,XIAP,YJU2,ZEB2,ZFP91,ZNF622,ZNF675 |
| GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 62 | 22 | AZIN1,OAZ3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SLC7A11 |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS | 0.0e+00 | 0.0e+00 | 1930 | 134 | 31 | ABRAXAS2,AURKB,CCNB1,CENPA,CHMP4B,CHMP5,CLASP2,CLTC,DRG1,ESPL1,HNRNPU,KPNB1,MCPH1,MECP2,NDEL1,NEK2,NSFL1C,NUF2,NUP62,NUSAP1,PRC1,RACGAP1,RAE1,RAN,RCC1,SBDS,STAG1,STAG2,TNKS,TPX2,WDR62 |
| GO_METHYLATION | 0.0e+00 | 0.0e+00 | 1930 | 366 | 52 | ALKBH8,AMT,AS3MT,BAZ2A,BRD4,CBLL1,DOT1L,DPH5,EEF1AKMT2,EZH1,FBXO11,GSK3A,GSPT1,H1-4,HSD17B10,KDM6A,KMT2A,KMT2B,KMT5A,MECP2,METTL21A,METTL4,MIS18A,MRM3,MTERF4,NSD2,NSD3,NSUN3,PAF1,PHF1,PRDM4,PWP1,RBM15,RIF1,SETD4,SETDB1,SIRT1,SMAD4,SMYD5,SNRPB,SNW1,SUPT6H,TET3,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,VIRMA,WDR4,ZCCHC4,ZNF335 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1930 | 976 | 94 | ACD,AIDA,ARRDC3,AURKB,AXIN1,BAG2,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK1,CDK12,CDK5RAP3,CHORDC1,CHTF18,DAXX,DBNDD2,DCUN1D2,DGKZ,DKC1,DNAJA1,DVL3,EDN1,FAF1,FBXO7,FEM1B,FGFR1OP,GFRAL,GGNBP2,GSK3A,HGS,HNRNPU,IBTK,IPO7,IQGAP3,IRAK3,JTB,KLF4,LYN,MAP2K7,MAP4K4,MASTL,MBIP,MCPH1,NAF1,NEK2,NEK7,NUP62,PABPN1,PAK1,PAK2,PDCD10,PEA15,PRKRIP1,PTPN11,RAB1A,RAP2C,RICTOR,RPS7,SFN,SIRT1,SLC11A1,SMG8,SOCS6,SOD1,SPDYA,STK10,TAB2,TELO2,TNFRSF10A,TNKS,TPX2,TRAF2,TRAF4,TSC1,UBB,UBC,UBE2C,UBE2I,UVRAG,VAV2,WASHC1,ZEB2,ZFP91,ZNF16,ZNF622,ZNF675 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1930 | 1030 | 97 | AATF,ADNP2,AIPL1,ALKBH1,ANKLE2,AP2B1,ARAF,ARL6IP1,ATAD3A,ATF4,AURKB,BAG1,BAG3,BAG4,BCL2L12,BCL2L2,BID,BNIP1,BNIP2,BTBD10,CASP3,CD200R1,CDK1,CHMP4B,CLCF1,CREB1,CSNK2A2,DDB1,DNAJA1,DNAJB6,EDN1,FBXO7,FOXC1,GFRAL,GNRH1,HMGB2,HNRNPK,HSF1,HSPA9,ITCH,KLF4,MAP4K4,MAPK8,MARCHF7,MDM4,MECP2,MED1,NAA35,NDUFS3,NFE2L2,NFKB1,NONO,NOTCH1,NUP62,OXR1,PAK2,PARP2,PDCD10,PEA15,PHB2,PHIP,PPIF,PSMC1,PSMG2,RAD18,REL,SET,SFN,SIRT1,SIX4,SLC25A5,SLC7A11,SMAD4,SOD1,SUPV3L1,TAF9B,TAX1BP1,TBX3,TCF7L2,TNFRSF10A,TNFRSF10D,TNIP2,TRAF2,TSC1,TYRO3,UBB,UBC,UBE2Z,UFL1,UNG,USP47,VDAC2,VPS35,XIAP,YAP1,ZC3HC1,ZNF16 |
| GO_TELOMERE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 175 | 35 | ACD,ATM,AURKB,BRCA2,DCP2,DKC1,DOT1L,EXOSC10,GAR1,H4-16,HNRNPA1,HNRNPU,HUS1B,LTO1,MAP2K7,NAF1,NEK2,NEK7,NSMCE2,PML,POLE,RAD51,RECQL4,RFC1,RIF1,RPA2,SMG1,SMG5,SMG7,TELO2,TERF2IP,TFIP11,TNKS,USP7,ZSCAN4 |
| GO_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 166 | 34 | DPF2,FOXC1,HSPA9,ITCH,KMT2A,N4BP2L2,NFE2L2,NOTCH1,NUDT21,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUS7,SLC7A6OS,TCF3,TOP2A,YAP1,YTHDF2 |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 547 | 65 | AKAP8L,ATG12,AXIN1,CAMSAP1,CAPN10,CAPN2,CASP3,CCNB1,CCNB2,CDK1,CDK5RAP3,CHMP5,CISD2,CKAP2,CKAP5,CLASP2,CSNK2A2,CTSL,DENR,DFFB,DVL3,EIF5A,EXOG,FBXO7,GABARAPL1,GRWD1,GSK3A,GSPT1,HDGFL3,HMGB2,HSF1,HSPA8,IRAK3,KIF18A,KIF2C,KPNB1,LCP1,MFN2,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTIF2,MTPN,MTRF1L,NDEL1,OGFOD1,PEX14,SCAF4,SCAF8,SET,SMURF1,TFIP11,TOP2A,TWF1,UBQLN4,USP30,UVRAG,VDAC1,VPS4A,WASHC1 |
| GO_STEM_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 252 | 42 | CDK12,EDN1,FOXC1,FRZB,HNRNPU,HSPA9,ITCH,KBTBD8,KMT2A,N4BP2L2,NFE2L2,NOTCH1,NUDT21,OCIAD1,PEF1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUS7,PWP1,SMAD4,TCF3,YAP1,YTHDF2,ZEB2 |
| GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 299 | 46 | ATM,BID,BRD4,CCNA2,CCNB1,CDC25A,CDC25C,CDC6,CDK1,CDK2,CDT1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,CUL1,CUL3,CUL4A,FBXO7,GSPT1,HINFP,IQGAP3,KLF4,LSM11,MCM7,MDM4,MTBP,ORC6,PAF1,PHB2,PML,POLE,PSME2,RBBP8,RCC1,RFWD3,RPA2,RPA4,SFN,SPDYA,TFDP2,WEE1 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT | 0.0e+00 | 0.0e+00 | 1930 | 79 | 24 | ATM,BAG1,BAG2,BAG3,BAG4,CAMK2G,CHORDC1,CREBBP,DNAJB1,DNAJB6,DNAJC2,DNAJC7,HSF1,HSPA8,HSPH1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,RAE1,RPA2,SIRT1 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1930 | 1429 | 120 | ABL2,ACAP2,ACD,ADRM1,AGAP6,AHSA2P,ANP32B,APH1A,ARHGAP11B,ARHGAP19,ARRDC3,AURKB,AXIN1,AZIN1,BID,BNIP2,CASP10,CASP3,CCNB1,CCNK,CCNT1,CCNT2,CDC6,CDK1,CHTF18,CLDN4,COA8,CWF19L1,CYB5B,DAXX,DCP1A,DCUN1D2,DDX11,DENND1B,DEPDC1,DGKZ,DKC1,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC9,DOCK2,DVL3,EDN1,GDI2,GFRAL,GNA13,GSK3A,GTF2F1,GTF2H2,HMGB2,HNRNPU,HSCB,HSF1,IQGAP3,JTB,KHDC1L,KLF4,LYN,MAP2K7,MAP4K4,MAPK8,MASTL,MTCH1,NAF1,NCAPH,NDEL1,NEK2,NEK7,PABPN1,PAK1,PAK2,PDCD10,PEA15,PLAA,PML,PPP1R15A,PSME2,PTPN11,RAB11FIP2,RAB1A,RAB3GAP1,RACGAP1,RANGAP1,RASA2,RCC2,RFC1,RGPD6,RICTOR,SENP1,SIRT1,SLC11A1,SOD1,SPDYA,STK10,TAB2,TBC1D15,TBC1D22B,TELO2,TNFRSF10A,TNKS,TPX2,TRAF2,TRAF4,TRIM23,TSC1,UBA2,UBB,UBC,UBE2C,UBE2I,VAV2,WNT9B,XRCC4,ZC3H15,ZEB2,ZFP91,ZNF16,ZNF622 |
| GO_MITOCHONDRIAL_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 258 | 42 | ATF2,ATP5F1B,ATP5MG,ATP5PB,BAG3,BAG4,BAP1,BID,BLOC1S2,CSNK2A2,CYC1,FBXO7,GRPEL1,GRPEL2,GSK3A,MAIP1,MAPK8,MCUR1,MFN2,MTERF4,PMPCB,PPIF,PPP3CC,PPP3R1,RNF31,SAMM50,SFN,SLC25A28,SLC25A32,SLC25A33,SLC25A38,SLC25A5,STOML2,TFDP2,TIMM10,TIMM10B,TIMM44,TIMM50,UBE2D3,UCP3,UQCRC2,VPS35 |
| GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1930 | 106 | 27 | ATF2,ATM,CCNB1,CDC25C,CDC6,CDK1,CDK2,CDK5RAP3,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,HUS1B,MDM4,MUS81,NAE1,PML,RFWD3,RPA2,SFN,SYF2,TFDP2,TOP2A,TOPBP1 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 193 | 36 | AAR2,AGO2,ATM,BRIX1,CD2BP2,CELF1,CPSF6,CPSF7,DDX1,DENR,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF5,ISY1,KHDC4,LUC7L2,NAF1,NUDT21,PPAN,PRPF18,RBMX,SART1,SART3,SF1,SF3A2,SF3A3,SLU7,SNRPB,SRPK1,TFIP11,XAB2,ZRSR2 |
| GO_SPINDLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 107 | 27 | ABRAXAS2,AURKB,CENPW,CHMP4B,CHMP5,DRG1,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HNRNPU,KPNB1,NCOR1,NEK2,NEK7,RACGAP1,RCC1,RNF4,SENP6,STAG1,STAG2,STARD9,TNKS,TPX2,TUBB |
| GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 164 | 33 | BRCA2,BRD4,CCNB1,CDC25A,CDC25C,CDC6,CDCA5,CDK1,CDT1,CUL3,CUL4A,DTL,DYNC1LI1,EDN1,ESPL1,HNRNPU,HSF1,KLHL18,LSM11,MECP2,MTA3,MTBP,NSFL1C,NSMCE2,NUP62,NUSAP1,PHB2,PHIP,PTPN11,RCC2,SH2B1,SLF1,UBE2C |
| GO_CELL_CELL_SIGNALING_BY_WNT | 0.0e+00 | 0.0e+00 | 1930 | 521 | 62 | AGO2,AP2B1,AXIN1,BCL7B,CLTC,CSNK1G1,CSNK2A2,CUL1,CUL3,DDB1,DVL3,FBXW11,FRZB,GID8,GNB1,GSK3A,HIC1,KDM6A,KLF4,LRRFIP2,NFKB1,NOTCH1,PAF1,PFDN5,PPM1A,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN23,RNF138,SMURF1,STRN,TCF7L2,TNKS,UBB,UBC,USP47,VPS26A,VPS35,WNT9B,XIAP,YAP1,ZBTB33,ZEB2,ZNRF3 |
| GO_PROTEIN_FOLDING | 0.0e+00 | 0.0e+00 | 1930 | 220 | 38 | BAG1,BAG2,BAG3,BAG4,CHORDC1,CSNK2A2,CWC27,DNAJA1,DNAJA2,DNAJB1,DNAJB14,DNAJB6,DNAJC2,DNAJC7,ERO1B,GNB1,GRPEL1,GRPEL2,HSP90AA2P,HSP90AA4P,HSP90AB4P,HSP90B2P,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,MPDU1,NFYC,PDCL,PDCL3,PFDN4,PFDN5,PPIF,PPIG,PSMC1,ST13,VBP1 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 643 | 70 | AP1G1,BTK,CACTIN,CD226,CGAS,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,EDN1,FBXW11,GPATCH3,HMGB2,IL18RAP,IRAK3,ITCH,LYN,MATR3,MED1,MUC13,NDEL1,NFKB1,NONO,NPLOC4,OTUD4,PAK1,PAK2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,SNW1,SUCNR1,TAB2,THBD,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,VAMP7,XIAP |
| GO_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 1005 | 93 | ACTR3,AKAP8,ANKHD1,AP1G1,BTK,CACTIN,CAMK2G,CD226,CGAS,CLEC4A,CNPY3,CRCP,CREBBP,CTSL,CUL1,DDX1,DDX60,ECSIT,EDN1,ERAP1,FBXW11,GPATCH3,HMGB2,IGHV3-43,IL18RAP,ILRUN,IPO7,IRAK3,ITCH,KRT16,LYN,MATR3,MED1,MUC13,NFKB1,NMI,NONO,NPLOC4,OTUD4,PAK1,PAK2,PARP14,PCBP2,PML,POLR3C,POLR3E,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RIOK3,RPS6KA5,SLC11A1,SRPK1,TAB2,TICAM1,TNIP2,TRIM23,TRIM56,TUBB,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,USP14,VAMP7,XIAP,YTHDF2,YTHDF3,ZC3HAV1 |
| GO_MEMBRANE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 875 | 85 | ABCA1,ACTR3,AKAP8L,ANKLE2,AP2B1,AP3B1,ARL6IP1,ATF2,ATP5F1B,ATP5MG,ATP5PB,AURKB,BAIAP2L1,BID,BIN1,BLOC1S2,BNIP1,CCNB1,CCNB2,CD3G,CDK1,CEP55,CHCHD3,CHMP4B,CHMP5,CLTA,CLTB,CLTC,CNIH1,CUL3,DNM2,DOCK2,GET3,GOSR1,GSK3A,HGS,HSPA8,IGHV3-43,KLHL21,LEMD2,MAIP1,MAPK8,MFN2,MTCH1,NDEL1,NSFL1C,PEF1,PLEKHA3,PPIF,PPP3CC,PPP3R1,PPP6R1,RAB1A,REPS1,RER1,SAMM50,SAR1A,SEC24B,SEC24C,SFN,SH3KBP1,SLC25A5,SLC4A1,SLC7A11,SMURF1,SOD1,STAM,STX16,STX18,SYT1,TAP2,TFDP2,TIMM10,TIMM50,TMED2,TMEM11,TMEM170A,TRAPPC10,UBB,UBC,UVRAG,VAMP7,VAPA,VPS4A,VTI1A |
| GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME | 0.0e+00 | 0.0e+00 | 1930 | 78 | 23 | CELF1,FMR1,FXR1,HNRNPA1,HNRNPL,HNRNPU,NSRP1,PQBP1,RBM10,RBM15,RBM17,RBM25,RBM4B,RBM7,RBM8A,RBMX,RNPS1,SART3,SCNM1,SLU7,SMU1,SREK1,SRSF4 |
| GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 168 | 33 | BTK,CUL1,FBXW11,FER,IGKV1D-33,LYN,MAP2K7,MAPK8,NFKB1,PAK1,PAK2,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TAB2,VAV2 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | 0.0e+00 | 0.0e+00 | 1930 | 233 | 39 | ATF4,ATP6V0A2,ATP6V1G1,CCNA2,CCNB1,CPEB1,CREBBP,EDN1,EGLN2,GNB1,HP1BP3,MDM4,NFE2L2,NOTCH1,PHB2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SIRT1,TMEM199,TSC1,UBB,UBC |
| GO_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 190 | 35 | ACD,ATM,AURKB,CHTF18,DCP2,DKC1,DNAJC2,DTL,EXOSC10,GAR1,HNRNPA1,HNRNPU,KLF4,LIN9,MAP2K7,NAF1,NEK2,NEK7,NPLOC4,POLE,POLK,POLL,RCHY1,RFC1,RPA2,SH2B1,SIRT1,SMG5,SMG7,TELO2,TERF2IP,TNKS,UBB,UBC,UFD1 |
| GO_REGULATION_OF_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 190 | 35 | AKAP8,AKAP8L,ATAD2,ATM,BRD4,CCNB1,CHEK1,FMR1,H1-4,HNRNPU,KAT7,KMT2A,KMT2B,MAPK8,MECP2,METTL4,MIER1,NSD3,PAF1,PHF1,RIF1,RNF40,RPS6KA5,SART3,SET,SETDB1,SIRT1,SMAD4,SNW1,SPTY2D1,SUPT6H,TADA2B,TLK2,TRIP12,ZNF335 |
| GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 201 | 36 | BTN2A1,BTN2A3P,CD226,CD3G,CUL1,DENND1B,EIF2B4,FBXW11,NFKB1,NFKBID,PAK1,PAK2,PAWR,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RC3H1,RNF31,STOML2,TAB2 |
| GO_REGULATION_OF_HEMOPOIESIS | 0.0e+00 | 0.0e+00 | 1930 | 477 | 58 | AP3B1,ATXN1L,BTK,CNOT4,CREB1,CREBBP,CUL4A,DPF2,FBXO7,FOXC1,H4-16,HMGB2,HOXA9,HSPA9,ITCH,KMT2A,KMT2B,LYN,MED1,N4BP2L2,NFE2L2,NFKBID,NKAP,NOTCH1,NUDT21,PAF1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUS7,RBM15,RC3H1,SART1,SENP1,SOD1,SPINK5,TCF3,YAP1,YTHDF2,ZEB1,ZNF16,ZNF675 |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1930 | 1625 | 128 | AIDA,AKAP8,AKAP8L,ANKLE2,ARAF,ATM,AXIN1,BAG4,BANK1,BRD4,BTBD10,C3orf33,CACTIN,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK1,CDK12,CDK5RAP3,CHORDC1,CLCF1,CNOT9,DAXX,DBNDD2,DGKZ,DNAJA1,DVL3,EDN1,FAF1,FBXO7,FER,FGFR1OP,FMR1,FXR1,GFRAL,GGNBP2,GSK3A,HGS,HNRNPU,HSF1,IBTK,IPO7,IQGAP3,IRAK3,ITCH,JTB,KLB,KLF4,LEMD2,LYN,MAP2K7,MAP4K4,MBIP,MCM7,MCPH1,NCOR1,NOTCH1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PAK1,PAK2,PARD3,PARP14,PDCD10,PDCL3,PEA15,PFKFB3,PHB2,PHIP,PML,PPIF,PPIL4,PPP2R5D,PPP2R5E,PRKRIP1,PTPN11,PWP1,RAD51,RAE1,RAP2C,RICTOR,RPS6KA5,SFN,SIRT1,SLC11A1,SLC25A33,SMAD4,SMG8,SOCS6,SOD1,SPDYA,SRPX2,STK10,TAB2,TELO2,TERF2IP,TMEM119,TNFRSF10A,TPX2,TRAF2,TRAF4,TSC1,TWF1,UBB,UBC,UBE2K,UVRAG,VAV2,WASHC1,WNT9B,YES1,ZEB2,ZFP91,ZNF16,ZNF622,ZNF675 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 0.0e+00 | 0.0e+00 | 1930 | 97 | 25 | CLEC4A,ERAP1,MICB,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SEC24B,SEC24C,TAP2 |
| GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | 0.0e+00 | 0.0e+00 | 1930 | 133 | 29 | ATM,BABAM1,BID,BRCA2,CCNB1,CDC25C,CDK1,CDK2,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,DTL,EEF1E1,HIC1,KAT5,KMT5A,MARCHF7,MDM4,PML,SFN,SIRT1,TFDP2,UIMC1,YJU2 |
| GO_PROTEIN_TARGETING | 0.0e+00 | 0.0e+00 | 1930 | 428 | 54 | AP3B1,AP4S1,ARL6IP1,BAAT,BAG3,BAG4,BAP1,BID,CHMP4B,CSNK2A2,FBXO7,GET3,GRPEL1,GRPEL2,GSK3A,HGS,HSPA8,MAIP1,MFN2,MTERF4,PAK1,PARD3,PEX14,PMPCB,RABGEF1,RNF31,RPL21,RPL22,RPS7,SAMM50,SEC61A2,SEC62,SEC63,SMURF1,SNX16,SPCS2,SRP72,SSR1,SSR2,SSR3,TIMM10,TIMM10B,TIMM44,TIMM50,UBB,UBC,UBE2D3,UQCRC2,VAMP7,VPS37A,VPS4A,VTI1A,WASH3P,ZDHHC18 |
| GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 81 | 23 | AZIN1,OAZ3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SLC7A11,VPS35 |
| GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 388 | 51 | ARAF,ATXN3,AXIN1,AZIN1,BAG2,CDK5RAP3,COP1,CSNK2A2,DDA1,DDB1,DERL2,DTL,EGLN2,FAF1,FMR1,GSK3A,HGS,IRAK3,ITCH,MARCHF7,MDM4,NFE2L2,NUDT15,OAZ3,PDCL3,PML,PSMC1,PSMC2,PSMC4,PSMD1,PSMD2,PSME2,RCHY1,RHBDD3,RNF19B,RNF40,RPS7,SENP1,SMURF1,SUMO2,TLK2,UBB,UBE2K,UBE3A,UBQLN4,UFL1,USP14,USP7,VPS35,WAC,ZFAND2A |
| GO_FC_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 240 | 39 | ACTR3,BTK,CD200R1,CD3G,CUL1,FBXW11,FER,IGKV1D-33,LYN,MAP2K7,MAPK8,NCKAP1,NFKB1,PAK1,PAK2,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TAB2,VAV2,WASF2,YES1 |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 1124 | 99 | AIPL1,AP1G1,ATM,BAP1,BRD4,BTK,CACTIN,CD200R1,CD226,CGAS,CLASP2,CLEC4A,CNPY3,CREBBP,CTSL,CUL1,DDX60,EDN1,ERAP1,FBXW11,GPATCH3,GRK7,HMGB2,IL18RAP,ILRUN,IRAK3,ITCH,KLF4,LYN,MATR3,MCPH1,MED1,MICB,MUC13,NDEL1,NFE2L2,NFKB1,NMI,NONO,NOTCH1,NPLOC4,OTUD4,PAK1,PAK2,PARP14,PCBP2,POLR3C,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RHBDD3,RICTOR,RIOK3,RPS6KA5,SERPINC1,SNW1,SOD1,SOX15,SPINK5,SUCNR1,TAB2,TBR1,THBD,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,USP14,VAMP7,VPS35,XIAP,YTHDF2,YTHDF3 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 724 | 74 | ACD,ANKRD13D,ATAD2,ATM,AURKB,BAG3,BAG4,BUB1,CAMSAP1,CCNB1,CDT1,CHEK1,CHMP4B,CKAP2,CLASP2,DCP2,DENND5A,DNAJB1,DNAJB6,DNM2,DYNC1LI1,ESPL1,EXOSC10,GSK3A,H1-4,HDGFL3,HNRNPA1,HNRNPU,HSF1,HSPA8,IFRD1,IRAK3,LRRTM2,MTBP,MTMR2,MTPN,NEK2,NME6,NOTCH1,PATL2,PEX14,PHF1,PPIF,PPM1A,PSMG2,RAD1,RAD21,RCC2,RIOK3,RNF6,RUFY3,SCAF4,SCAF8,SET,SIRT1,SLC25A5,SMAD4,SPART,SUPT6H,TCHP,TERF2IP,TFIP11,TNKS,TOP2A,TRIP12,TSC1,TWF1,UBE3A,UBQLN4,USP30,VDAC2,VPS35,WAPL,WASF2 |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 0.0e+00 | 0.0e+00 | 1930 | 1200 | 103 | ACTR3,AKAP8,ANKHD1,AP1G1,BTK,CACTIN,CAMK2G,CD226,CGAS,CLEC4A,CNPY3,CRCP,CREBBP,CTSL,CUL1,DDX1,DDX60,ECSIT,EDN1,ERAP1,EXOSC4,EXOSC5,FBXW11,GPATCH3,HMGB2,IGHV3-43,IL18RAP,ILF3,ILRUN,IPO7,IRAK3,ITCH,KRT16,LGALS8,LYN,LYZ,MATR3,MED1,MICB,MUC13,NFKB1,NMI,NONO,NPLOC4,NT5C3A,OTUD4,PAK1,PAK2,PARP14,PCBP2,PML,POLR3C,POLR3E,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RAB14,RAB1A,RIOK3,RPS6KA5,SLC11A1,SPINK5,SRPK1,TAB2,TICAM1,TNIP2,TRIM23,TRIM56,TUBB,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,USP14,VAMP7,XIAP,YTHDF2,YTHDF3,ZC3HAV1 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | 0.0e+00 | 0.0e+00 | 1930 | 110 | 26 | AP2B1,CLTC,DVL3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SEC24B,SMURF1,WNT9B,ZNRF3 |
| GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 150 | 30 | AGO2,AP2B1,CLTC,DVL3,FRZB,GNB1,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SMURF1,TCF7L2,WNT9B,ZNRF3 |
| GO_NIK_NF_KAPPAB_SIGNALING | 0.0e+00 | 0.0e+00 | 1930 | 183 | 33 | ADIPOR1,CUL1,EDN1,FBXW11,NFKB1,PPM1A,PPP4C,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RC3H1,REL,TERF2IP,TNFRSF10A,TRAF2,TRAF4,ZFP91 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 252 | 39 | ARAF,ATXN3,AXIN1,BAG2,CDK5RAP3,COP1,CSNK2A2,DDA1,DERL2,FAF1,FMR1,GSK3A,MARCHF7,NFE2L2,NUDT15,PDCL3,PML,PSMC1,PSMC2,PSMC4,PSME2,RCHY1,RNF19B,RNF40,RPS7,SENP1,SMURF1,SUMO2,TLK2,UBB,UBE2K,UBE3A,UBQLN4,UFL1,USP14,USP7,VPS35,WAC,ZFAND2A |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 406 | 51 | ACTR3,AP3B1,ATM,BLOC1S2,BTK,C12orf4,CCNB1,CDCA5,CDT1,CENPA,CENPQ,CEP120,CHMP4B,CHMP5,CLASP2,CNIH1,CUL3,DNM2,ESPL1,FER,GOSR1,HNRNPU,KIF18A,KIF2C,KLHL21,KPNB1,LYN,MCPH1,MIS12,MYO19,NDEL1,NSFL1C,NUF2,NUP62,NUSAP1,PARD3,PCM1,PDCD10,PEF1,PEX14,PPP6R1,RAB1A,RAN,SAR1A,SEC24B,SEC24C,TMED2,TRAPPC10,UBB,VAMP7,VPS4A |
| GO_RESPONSE_TO_INTERLEUKIN_1 | 0.0e+00 | 0.0e+00 | 1930 | 207 | 35 | CACTIN,CUL1,EDN1,FBXW11,IRAK3,NFKB1,OTUD4,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RBMX,RC3H1,RPS6KA5,TAB2,TNIP2,UBB,UBC,YY1,ZNF675 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 1930 | 232 | 37 | ARRDC3,AXIN1,BAG2,CDK5RAP3,CUL3,DAXX,DCUN1D2,DNAJA1,FANCI,FANCM,FBXO2,FEM1B,GSK3A,ITCH,MARCHF7,MASTL,MTBP,NMI,OTUD4,PEF1,PLAA,RAB1A,RCHY1,RNF40,RPS7,SART3,SPOPL,TICAM1,TRIP12,UBB,UBE2C,UBE2I,UBE3A,UFL1,WASHC1,WDR48,XIAP |
| GO_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1930 | 735 | 73 | ADRM1,ANP32B,ARAF,ARL6IP1,ATXN3,AXIN1,BAG2,BCL2L12,BID,BIN1,C2CD3,CASP10,CLDN4,CLN6,COA8,COL6A3,COP1,CPAMD8,CSNK2A2,DDA1,DERL2,DNAJB6,FBXW11,FMR1,GSK3A,HSF1,INPP5B,ITCH,KHDC1L,KLF4,LYN,MARCHF7,MTCH1,NFE2L2,NUDT15,OTUD4,PAK2,PDCL3,PML,PSMA3,PSMC1,PSMC2,PSMC4,PSME2,RCHY1,RNF19B,RNF40,RPS7,SART3,SENP1,SERPINC1,SFN,SIRT1,SMURF1,SPINK5,SPOPL,SUMO2,TLK2,TNFRSF10A,TRAF2,UBB,UBE2K,UBE2Z,UBE3A,UBQLN4,UFL1,USP14,USP47,USP7,WAC,WDR48,XIAP,ZFAND2A |
| GO_MEIOTIC_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 187 | 33 | ACTR3,ATM,BRCA2,BUB1,CCNB1IP1,CDC25A,CDC25C,DMC1,ESPL1,FANCM,HSF1,HUS1B,KIF18A,KLHDC3,MASTL,MCMDC2,MND1,MSH4,MUS81,NCAPH,NCAPH2,NUF2,PSMC3IP,RAD1,RAD21,RAD51,RAD54L,SMC4,SPDYA,TOP2A,UBB,WAPL,YTHDF2 |
| GO_MITOTIC_SPINDLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 107 | 25 | ABRAXAS2,AURKB,CCNB1,CHMP4B,CHMP5,CLASP2,CLTC,DRG1,HNRNPU,KPNB1,MECP2,NEK2,NUF2,NUP62,PRC1,RACGAP1,RAE1,RAN,RCC1,SBDS,STAG1,STAG2,TNKS,TPX2,WDR62 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 802 | 77 | ABHD17B,AKAP8L,ANP32B,AP2B1,ATAD1,BAG3,BAG4,BAP1,BID,C12orf4,CAPN10,CDCA5,CDK1,CDK5RAP3,CDT1,CENPQ,CEP72,CLTC,CPSF6,CSNK2A2,CTDSPL2,DERL2,DKC1,DNAJA1,DPP10,DVL3,FER,GOSR1,GSK3A,HNRNPU,ILRUN,KAT7,LCP1,LYN,LZTFL1,MAPK8,MTMR2,MYLK2,NDEL1,NSFL1C,NUP153,NUP62,OTUD7B,PAK1,PARD3,PCM1,PDCD10,PML,PPM1A,PPP3CC,PPP3R1,PTPN11,PTPN23,RAB11FIP2,RAB21,RAN,RANGAP1,RBM22,RBM26,RBM27,RER1,RNF31,RUFY3,SAR1A,SEC24B,SFN,SLC7A11,STX18,SUPT6H,TCF7L2,TFDP2,UBE2D3,VAMP7,VPS35,VPS4A,WAPL,XPO4 |
| GO_REGULATION_OF_MRNA_3_END_PROCESSING | 0.0e+00 | 0.0e+00 | 1930 | 28 | 14 | CCNB1,CCNT1,CPEB1,CPSF6,CPSF7,HSF1,NUDT21,PAF1,PAPOLA,RNF40,SNRPA,VIRMA,ZC3H14,ZC3H3 |
| GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 147 | 29 | AXIN1,CSNK1G1,GID8,NFKB1,PPM1A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TNKS,USP47,VPS35,XIAP,YAP1 |
| GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 500 | 57 | ACTR3,BTK,BTN2A1,BTN2A3P,CD200R1,CD226,CD3G,CLEC4A,CREBBP,CUL1,DENND1B,EIF2B4,ELF2,FBXW11,FER,IGHV3-43,IGKV1D-33,LPXN,LYN,MAP2K7,MAPK8,MICB,MUC13,NCKAP1,NFKB1,NFKBID,PAK1,PAK2,PAWR,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RC3H1,RNF31,RPS6KA5,STOML2,TAB2,VAV2,WASF2,YES1 |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1935 | 141 | ABCA1,ABCB7,ABL2,ACD,ACER1,ADIPOR1,AIPL1,AKR1C1,ANKRD11,ARRDC3,ATF4,ATM,ATP13A3,ATP5F1B,ATP6V0A2,ATP6V1G1,ATP6V1H,AURKB,BAG3,BAP1,BRCA2,CASP3,CCNB2,CHERP,CHMP4B,CLDN4,CLN6,CNOT3,COX19,CREBBP,CRTC3,CUL1,DCP2,DDB1,DKC1,EDN1,EGLN2,ERO1B,EXOSC10,FOXC1,FOXK2,GALR2,GAR1,GLRX3,GNA13,GNB1,GPR89A,GPR89B,GSR,H4-16,HKDC1,HMGB2,HNRNPA1,HNRNPU,HSF1,HSPA9,HUS1B,IBTK,IQCB1,ITPR3,JMJD6,KDM6B,KRT16,LIPC,LTO1,LYN,LYZ,MAFG,MAIP1,MAP2K7,MCUR1,MED1,MED13,MFN2,MUC13,NAF1,NEK2,NEK7,NFE2L2,NOTCH1,NSMCE2,NUCKS1,OR56A4,PKNOX1,PLAA,PML,POLE,PRKAB1,PTPN11,QSOX2,RAB11FIP2,RAB38,RAD51,RALY,RC3H1,RECQL4,RFC1,RIF1,RPA2,SART3,SENP1,SFN,SIRT1,SLC11A1,SLC25A28,SLC25A38,SLC30A5,SLC39A8,SLC41A1,SLC4A1,SLC66A1,SLC7A11,SLMAP,SMAD4,SMG1,SMG5,SMG7,SNX5,SOD1,SP3,STOML2,SUCNR1,TCF7L2,TELO2,TERF2IP,TFIP11,TMEM119,TMEM199,TNKS,TXNL1,TYRO3,UBB,UBE2C,UBE2K,USP7,WDR48,XIAP,YAP1,ZNF16,ZNF675,ZSCAN4 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 1881 | 138 | ABCA1,ABL2,ADIPOR1,ANP32B,AP3B1,ATF1,BIN1,BNIP2,BTK,CAPN2,CDK1,CDK12,CDK5RAP3,CLASP2,CLCF1,CNOT4,CREB1,CREBBP,CTSL,CUL4A,DENND5A,DMRTA2,DNM2,DPF2,DVL3,EDN1,ELF5,FBXO7,FMR1,FOXC1,FOXJ2,FRZB,GNRH1,GSK3A,H4-16,HMGB2,HNRNPU,HOXA11,HOXA9,HSPA9,IFRD1,IQCB1,ISL2,ITCH,ITSN2,KLF4,KMT2A,KMT2B,LYN,MAFG,MAPK6,MECP2,MED1,MED28,N4BP2L2,NAP1L1,NDEL1,NEPRO,NFE2L2,NFKB1,NFKBID,NKAP,NOTCH1,NUDT21,OCIAD1,PAF1,PAK1,PARP2,PCM1,PLAA,POFUT2,PQBP1,PRTG,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PUS7,PWP1,RAB21,RBM15,RC3H1,RCC2,RNF10,RNF6,RUFY3,SART1,SENP1,SF3A2,SFN,SIK1,SINHCAF,SIRT1,SIX4,SMAD4,SMURF1,SNW1,SOD1,SPART,SPINK5,SRRT,ST7,SUPT6H,SYT1,TBR1,TBX3,TCF3,TCF7L2,TMEM119,TSC1,TWF1,UBE3A,UFL1,VAMP7,WNT9B,YAP1,YTHDF2,YY1,ZEB1,ZEB2,ZNF16,ZNF335,ZNF675 |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1930 | 622 | 65 | AGO2,AP2B1,AXIN1,BCL7B,CLTC,CSNK1G1,CSNK2A2,CUL1,CUL3,DDB1,DVL3,FBXW11,FRZB,GID8,GNB1,GSK3A,HIC1,KDM6A,KLF4,LRRFIP2,MECP2,MTMR2,NFKB1,NOTCH1,PAF1,PFDN5,PPM1A,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAB3GAP1,RNF138,SMURF1,STRN,TCF7L2,TMEM108,TNKS,UBB,UBC,USP47,VPS26A,VPS35,WNT9B,XIAP,YAP1,ZBTB33,ZEB2,ZNRF3 |
| GO_RESPONSE_TO_OXYGEN_LEVELS | 0.0e+00 | 0.0e+00 | 1930 | 391 | 49 | ATF4,ATM,ATP6V0A2,ATP6V1G1,CAPN2,CASP3,CCNA2,CCNB1,CPEB1,CREB1,CREBBP,EDN1,EGLN2,GNB1,HP1BP3,HSF1,MDM4,MECP2,NFE2L2,NOTCH1,PAK1,PHB2,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SIRT1,SMAD4,TMEM199,TSC1,UBB,UBC,UCP3 |
| GO_TYPE_I_INTERFERON_PRODUCTION | 0.0e+00 | 0.0e+00 | 1930 | 129 | 27 | AZI2,CACTIN,CGAS,CRCP,CREBBP,GPATCH3,HMGB2,ILRUN,ITCH,LRRFIP1,NFKB1,NMI,NPLOC4,PCBP2,POLR3C,POLR3E,POLR3F,PQBP1,PTPN11,REL,RIOK3,TAX1BP1,TICAM1,TRAIP,TRIM56,UFD1,YY1 |
| GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1930 | 181 | 32 | ATM,AURKB,BCL2L12,CDK2,CDK5RAP3,CHEK1,CSNK2A2,DYRK2,EEF1E1,HIC1,HIPK1,HNRNPK,KAT5,KMT5A,MARCHF7,MDM4,PAK1IP1,PML,PRKAB1,RAD1,RBBP4,RBBP8,RPA2,RPS7,SIRT1,TAF2,TAF9B,TOP3A,TOPBP1,TPX2,UBB,YJU2 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 0.0e+00 | 0.0e+00 | 1930 | 76 | 21 | CLEC4A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TAP2 |
| GO_NUCLEOTIDE_EXCISION_REPAIR | 0.0e+00 | 0.0e+00 | 1930 | 111 | 25 | ATXN3,BRCA2,COPS2,COPS3,COPS7B,CUL4A,DDB1,ERCC8,GTF2H2,GTF2H2C,HUS1B,ISY1,NEIL3,POLE,POLK,POLL,RBBP8,RFC1,RPA2,RPA4,SIRT1,UBB,UBC,USP7,XAB2 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 537 | 59 | ABHD17B,AKAP8L,ANP32B,AP2B1,ATAD1,BAG3,BAG4,BAP1,BID,CDCA5,CDK1,CDK5RAP3,CDT1,CENPQ,CEP72,CLTC,CSNK2A2,CTDSPL2,DERL2,DKC1,DNAJA1,DPP10,DVL3,GSK3A,ILRUN,KAT7,LCP1,LZTFL1,MAPK8,NDEL1,NSFL1C,NUP62,OTUD7B,PAK1,PCM1,PDCD10,PPM1A,PPP3CC,PPP3R1,PTPN11,RAB11FIP2,RAN,RANGAP1,RBM22,RER1,RNF31,RUFY3,SAR1A,SFN,SLC7A11,SUPT6H,TCF7L2,TFDP2,UBE2D3,VAMP7,VPS35,VPS4A,WAPL,XPO4 |
| GO_REGULATION_OF_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 1930 | 122 | 26 | BABAM1,CGAS,CHEK1,CUL4A,DDX11,ERCC8,HELB,HSF1,NSD2,PML,PPP4C,PPP4R2,RAD51,RAD51AP1,RIF1,RPA2,SHLD1,SHLD2,SIRT1,SLF1,TERF2IP,TFIP11,TRIP12,UBQLN4,UIMC1,USP1 |
| GO_RESPONSE_TO_IONIZING_RADIATION | 0.0e+00 | 0.0e+00 | 1930 | 144 | 28 | ATM,BABAM1,BRCA2,CASP3,COP1,DNM2,ELK1,ERCC8,HSF1,INIP,INTS7,KAT5,LZIC,NUCKS1,PML,RAD1,RAD51,RAD51AP1,RAD54L,RFWD3,RRM1,SIRT1,THBD,TLK2,TOPBP1,UIMC1,XRCC4,YAP1 |
| GO_RRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 221 | 35 | C1D,DDX52,DDX54,DIS3,DKC1,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FCF1,FRG1,GAR1,MRM3,MTERF4,NAF1,NOL9,NSA2,NSUN3,PES1,POP7,RIOK3,RPS7,RRP1,RRP9,SART1,SBDS,SRFBP1,TEX10,THUMPD1,TSR1,TSR2,UTP18,WBP11,ZCCHC4 |
| GO_G1_DNA_DAMAGE_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1930 | 64 | 19 | ATM,CCNB1,CDC25C,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,MDM4,PML,RFWD3,RPA2,SFN,TFDP2,WAC |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1189 | 98 | AATF,AGO2,AIDA,ARL6IP1,ATF4,AZIN1,BAG2,BANK1,BCL2L12,BIN1,C3orf33,CACTIN,CASP3,CCNB1,CDK5RAP3,CELF1,CHORDC1,CNOT10,CNOT2,CNOT3,CNOT6L,CNOT9,COL6A3,CPAMD8,CPEB1,CSNK2A2,DBNDD2,DERL2,DNAJA1,DNAJB6,EDN1,EIF3E,FBXO7,FGFR1OP,FMR1,FXR1,GGNBP2,IBTK,ILF3,IPO7,IRAK3,ITCH,KLF4,LEMD2,LYN,MARCHF7,MASTL,MBIP,MDM4,NCOR1,NFKB1,NMI,NUP62,OXR1,PAK2,PARD3,PARP14,PATL2,PDCL3,PHF1,PLAA,PML,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R5D,PRKRIP1,PUM1,PUS7,PWP1,RC3H1,RPS7,SENP1,SERPINC1,SET,SFN,SIRT1,SMAD4,SPINK5,SPOPL,SUPT6H,TERF2IP,TLK2,TRIP12,TSC1,UBE2Z,UFL1,USP14,USP47,USP7,VPS35,WAC,XIAP,YTHDF2,YTHDF3,ZNF675 |
| GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1930 | 107 | 24 | ATM,BRCA2,CCNB1,CDC25C,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,EEF1E1,HIC1,KAT5,KMT5A,MARCHF7,MDM4,PML,SFN,SIRT1,TFDP2,YJU2 |
| GO_CELL_CYCLE_ARREST | 0.0e+00 | 0.0e+00 | 1930 | 237 | 36 | ATM,BIN1,CCNB1,CCNK,CDC25C,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,E4F1,EIF4G2,MCPH1,MDM4,MTBP,NOTCH1,PML,PPM1A,PPP1R15A,PRKAB1,PRR11,RASSF1,SDE2,SFN,SLC25A33,SLC38A9,TBRG1,TCF7L2,TFDP2,UHRF2,ZBTB49 |
| GO_REGULATION_OF_MRNA_POLYADENYLATION | 0.0e+00 | 0.0e+00 | 1930 | 17 | 11 | CCNT1,CPEB1,CPSF6,CPSF7,HSF1,NUDT21,RNF40,SNRPA,VIRMA,ZC3H14,ZC3H3 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1930 | 974 | 85 | AFP,ALKBH1,ANKRD49,ATM,BCL2L2,BRCA2,CASP3,CCNB1,CCNB1IP1,CDC25C,CELF1,CEP57,CFAP157,CIP2A,CNOT9,CSDE1,CSNK2A2,DAZAP1,DIAPH2,DMC1,DNAJA1,DNAJB6,DNM2,EIF2B4,FANCG,FEM1B,FOXC1,GGNBP2,GNRH1,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,ICA1L,INPP5B,KIF18A,KMT2B,LHFPL2,MCMDC2,MED1,MNS1,MSH4,NLRP14,NOTCH1,NR2C2,NUP62,OAZ3,ODF2,PHB2,PLK4,PTPN11,PUM1,RACGAP1,RAI14,RBM15,RNF38,RRM1,SF1,SIRT1,SIX4,SLC26A8,SMAD4,SNRPA1,SOD1,SOX15,SP3,SRPK1,TBX3,TIAL1,TMED2,TMEM119,TTC26,TYRO3,UBB,UBE3A,WDR48,WNT9B,YTHDF2,YY1,ZFP42,ZNF296,ZNF568 |
| GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 0.0e+00 | 0.0e+00 | 1930 | 82 | 21 | ACD,ATM,AURKB,DCP2,DKC1,EXOSC10,GAR1,HNRNPA1,HNRNPU,MAP2K7,NAF1,NEK2,NEK7,RAD51,RFC1,SMG5,SMG7,TELO2,TERF2IP,TNKS,ZSCAN4 |
| GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_CELL_CYCLE_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1930 | 74 | 20 | ATM,BABAM1,CCNB1,CDC25C,CDK1,CDK2,CHEK1,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,DTL,MDM4,PML,SFN,TFDP2,UIMC1 |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1930 | 1765 | 129 | ABCF1,ACTR3,AKAP8,ANKHD1,AP1G1,ATM,BAP1,BRD4,BTK,CACTIN,CAMK2G,CD200R1,CD226,CGAS,CLEC4A,CNPY3,CRCP,CREBBP,CTSL,CUL1,DDX1,DDX60,ECSIT,EDN1,ERAP1,EXOSC4,EXOSC5,FBXW11,GPATCH3,HMGB2,HSF1,IGHV3-43,IL18RAP,ILF3,ILRUN,IPO7,IRAK3,ITCH,KDM6B,KLF4,KRT16,LGALS8,LYN,LYZ,MATR3,MCPH1,MECP2,MED1,MEP1B,MICB,MUC13,NFE2L2,NFKB1,NFKBID,NMI,NONO,NOTCH1,NPLOC4,NT5C3A,OTUD4,PAK1,PAK2,PARP14,PCBP2,PLAA,PML,POLR3C,POLR3E,POLR3F,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PUM1,PUM2,RAB11FIP2,RAB14,RAB1A,REL,RHBDD3,RICTOR,RIOK3,RPS6KA5,SERPINC1,SLC11A1,SOCS6,SOD1,SPINK5,SRPK1,SUCNR1,TAB2,TIAL1,TICAM1,TNIP2,TRIM23,TRIM56,TUBB,TYRO3,UBB,UBC,UBE2D3,UBE2K,UFD1,USP14,VAMP7,VDAC1,VPS35,XIAP,YTHDF2,YTHDF3,ZC3HAV1,ZNF148 |
| GO_RNA_MODIFICATION | 0.0e+00 | 0.0e+00 | 1930 | 161 | 29 | ADAT2,ALKBH1,ALKBH3,ALKBH8,CBLL1,CDKAL1,DKC1,DUS3L,GAR1,HSD17B10,JMJD6,MRM3,MTERF4,NAF1,NSUN3,PUS1,PUS7,RBM15,RPUSD4,SEPHS1,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,VIRMA,WDR4,ZCCHC4 |
| GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | 0.0e+00 | 0.0e+00 | 1930 | 141 | 27 | BAG3,BAG4,BAP1,BID,CSNK2A2,DNAJA1,FBXO7,GRPEL1,GRPEL2,GSK3A,MAIP1,MAPK8,MFN2,MTERF4,PMPCB,PPP3CC,PPP3R1,RNF31,SAMM50,SFN,TFDP2,TIMM10,TIMM10B,TIMM44,TIMM50,UBE2D3,UQCRC2 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY | 0.0e+00 | 0.0e+00 | 1930 | 77 | 20 | AGO2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,DCP1A,DCP2,DIS3,EXOSC3,EXOSC4,EXOSC5,EXOSC9,NT5C3B,PABPC1,PATL2,RC3H1,TENT4A |
| GO_PROTEIN_MONOUBIQUITINATION | 0.0e+00 | 0.0e+00 | 1930 | 69 | 19 | CUL1,CUL3,DDB1,DTL,FANCM,KBTBD8,KLHL21,OBI1,PAF1,PCGF5,PEF1,RAD18,RNF126,RNF40,UBB,UBE2D3,UBE2T,WAC,WDR48 |
| GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 312 | 41 | BTK,BTN2A1,BTN2A3P,CD226,CD3G,CUL1,DENND1B,EIF2B4,ELF2,FBXW11,IGHV3-43,LPXN,LYN,NFKB1,NFKBID,PAK1,PAK2,PAWR,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RC3H1,RNF31,STOML2,TAB2 |
| GO_CILIARY_BASAL_BODY_PLASMA_MEMBRANE_DOCKING | 0.0e+00 | 0.0e+00 | 1930 | 95 | 22 | C2CD3,CDK1,CEP135,CEP57,CEP72,CEP76,CEP89,CKAP5,FBF1,FGFR1OP,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,IQCB1,NEK2,ODF2,PCM1,PLK4,TUBB |
| GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 394 | 47 | ACD,ATAD2,ATM,AURKB,BAG3,BAG4,BUB1,CAMSAP1,CCNB1,CDT1,CHEK1,CHMP4B,CKAP2,CLASP2,DCP2,DNM2,DYNC1LI1,ESPL1,EXOSC10,H1-4,HDGFL3,HNRNPA1,HNRNPU,MTBP,MTPN,NEK2,NME6,PATL2,PHF1,PPIF,PSMG2,RAD1,RAD21,SET,SIRT1,SLC25A5,SMAD4,SUPT6H,TCHP,TERF2IP,TNKS,TOP2A,TRIP12,TWF1,USP30,WAPL,WASF2 |
| GO_CHROMOSOME_CONDENSATION | 0.0e+00 | 0.0e+00 | 1930 | 47 | 16 | AKAP8,AKAP8L,CCNB1,CDCA5,CDK1,DFFB,H1-4,MCPH1,NCAPH,NCAPH2,NUSAP1,PHF13,SMC4,TENT4A,TOP2A,WAPL |
| GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR | 0.0e+00 | 0.0e+00 | 1930 | 78 | 20 | CGAS,CHEK1,DDX11,HELB,HSF1,NSD2,PML,PPP4C,PPP4R2,RAD51,RAD51AP1,RIF1,RPA2,SHLD1,SHLD2,SLF1,TERF2IP,TFIP11,TRIP12,UBQLN4 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION | 0.0e+00 | 0.0e+00 | 1930 | 250 | 36 | BAZ2A,BRF2,CCNB1,CDK1,CRCP,CREB1,CREBBP,DR1,E2F3,GTF2F1,GTF2H2,GTF3C3,H4-16,MECP2,MED1,MED10,MED13,MED17,MED27,MED30,MED31,MED6,NOTCH1,NR2C2,NR2C2AP,PSMC2,PSMC3,PSMC4,PSMC6,SNAPC5,SNW1,TAF2,TAF9B,TBPL2,TEAD4,YAP1 |
| GO_PROTEIN_ACETYLATION | 0.0e+00 | 0.0e+00 | 1930 | 202 | 32 | ACTL6A,ATF2,BRCA2,BRD1,CHEK1,CREBBP,DPF2,DR1,HAT1,ING3,KANSL1,KANSL2,KAT5,KAT7,KMT2A,MBIP,MECP2,MSL2,MSL3,NAA20,NAA25,NAA35,RPS6KA5,SET,SIRT1,SMAD4,SUPT7L,TADA1,TADA2B,TAF5L,TAF9B,TERF2IP |
| GO_REGULATION_OF_HISTONE_MODIFICATION | 0.0e+00 | 0.0e+00 | 1930 | 146 | 27 | AKAP8,AKAP8L,ATM,BRD4,CCNB1,CHEK1,FMR1,KAT7,KMT2A,KMT2B,MAPK8,MECP2,NSD3,PAF1,PHF1,RIF1,RNF40,RPS6KA5,SART3,SET,SIRT1,SMAD4,SNW1,SUPT6H,TADA2B,TRIP12,ZNF335 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 289 | 39 | ATF4,ATM,BCL2L12,BCL2L2,BID,BRCA2,CASP3,COA8,CUL1,CUL3,CUL4A,DNAJA1,DYRK2,HIC1,HINT1,HIPK1,HNRNPK,MARCHF7,MELK,NDUFS3,NFE2L2,NONO,PDCD10,PLAGL2,PML,PPIF,PPP1R15A,RPS7,SFN,SIRT1,SNW1,SOD1,TAF9B,TRAF2,UBB,UBE2K,USP47,VDAC2,ZNF622 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 106 | 23 | BRD4,CCNB1,CDC25A,CDC25C,CDC6,CDCA5,CDK1,CDT1,CUL3,CUL4A,DTL,ESPL1,KLHL18,LSM11,MECP2,MTA3,MTBP,NSMCE2,PAF1,PHB2,RCC2,UBE2C,ZNF16 |
| GO_ENDOSOMAL_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 228 | 34 | ABCA1,ACAP2,AP3B1,AP5Z1,BLOC1S2,CHMP4B,CHMP5,CLTC,DENND1B,DENND5A,GOSR1,HGS,NSG1,PTPN23,RAB14,RAB35,RBSN,RNF126,SNX5,STAM,STX16,TMEM87A,TRAPPC10,UBB,UBC,VPS26A,VPS35,VPS37A,VPS4A,VPS51,VTI1A,WASH3P,WASH6P,WASHC1 |
| GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 192 | 31 | ACD,ATM,AURKB,BABAM1,CDK2,CHTF18,CLCF1,DDX11,DKC1,ERCC8,EXOSC3,HNRNPA1,HSF1,KLF4,MAP2K7,MECP2,NAF1,NEK2,NEK7,NSD2,OTUD4,PML,RAD51,RIF1,SHLD1,SHLD2,SIRT1,SLF1,TNKS,UIMC1,USP7 |
| GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 181 | 30 | AXIN1,CSNK1G1,GID8,NFKB1,PPM1A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TNKS,USP47,VPS35,XIAP,YAP1,ZEB2 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 1545 | 115 | ABHD17B,ABITRAM,ABL2,ACTR3,ALKBH1,ATF1,ATMIN,BAG4,BLOC1S2,C12orf57,C2CD3,CAMSAP1,CASP3,CCDC13,CDK1,CDKL1,CEP120,CEP135,CEP57,CEP72,CEP76,CEP89,CFAP157,CKAP5,CNTROB,CREB1,CUL3,DENND5A,DNM2,DVL3,FBF1,FBXO7,FER,FGD1,FGFR1OP,FMR1,FOPNL,FXR1,FXYD5,GALR2,GSK3A,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,HDGFL3,IFRD1,IQCB1,ISL2,ITSN2,KLF4,LAMA2,LYN,MAP4K4,MAPK6,MCIDAS,MECP2,MNS1,MTMR2,NCKAP1,NDEL1,NEK2,NFE2L2,NOTCH1,ODF2,PAK1,PAK2,PARD3,PCM1,PDCL,PLAA,PLK4,PQBP1,PTPN11,PTPN23,RAB21,RAB35,RCC2,RNF6,RO60,RPS6KA5,RSPH4A,RUFY3,SEC24B,SF3A2,SH2B1,SH3KBP1,SMAD4,SMURF1,SOD1,SPART,STRN,SYT1,TBR1,TCHP,TMEM108,TSC1,TTC26,TUBB,TWF1,UBA6,UBB,UBE3A,USP21,VAMP7,VAPA,VAV2,VPS35,WASF2,WASHC1,WEE1,ZEB2,ZNF335 |
| GO_CHROMOSOME_SEPARATION | 0.0e+00 | 0.0e+00 | 1930 | 89 | 21 | ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDT1,CSNK2A2,CUL3,DYNC1LI1,ESPL1,FANCM,MSH4,MUS81,NCAPH,NCAPH2,NSMCE2,PSMG2,RAD21,TOP2A,TOP3A |
| GO_GROWTH | 0.0e+00 | 0.0e+00 | 1930 | 990 | 84 | ACTL6A,ADIPOR1,ADNP2,ALKBH1,ANKRD11,ATAD3A,ATM,BAP1,BLZF1,BRCA2,BRMS1L,CCNB1,CCNB2,CDK1,CDK11A,CDKN2AIP,COL6A3,COPS2,CREB1,CRLF3,DCAF1,DERL2,DNM2,E4F1,EDN1,EGLN2,EIF4G2,EXOSC4,EXOSC9,FGFR1OP,FOXC1,FRZB,GINS4,GSK3A,HOXA11,HSF1,IFRD1,ING3,ITCH,ITSN2,KAT5,KDM6A,MATN1,MED1,MTPN,NDEL1,NDUFS3,NME6,NOTCH1,PAK1,PAK2,PARP2,PLAA,PML,PTPN11,RAB21,RBBP6,RNF6,RUFY3,SBDS,SFN,SIRT1,SIX4,SLC25A25,SLC25A33,SMAD4,SMURF1,SOCS6,SOD1,SOX15,SPART,SUPV3L1,SYT1,TAF9B,TCHP,TMED2,TMEM108,UBE3A,USP47,WDR48,YAP1,YY1,ZEB2,ZNF639 |
| GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 431 | 49 | AADAC,AGO2,ATM,ATXN3,AXIN1,BAG2,BAG3,CNOT6L,COP1,DDA1,DDB1,DTL,EGLN2,FAF1,FBXO7,FMR1,GRSF1,GSK3A,HSF1,ITCH,KAT5,MFN2,NFE2L2,OAZ3,PABPC1,PFKFB3,PSMC1,PSMC2,PSMC4,PUM1,RAB3GAP1,RC3H1,RCHY1,RHBDD3,RNF19B,RNF40,SIRT1,SMURF1,SUMO2,SUPV3L1,TICAM1,TSC1,UVRAG,VPS35,WAC,YTHDF2,YTHDF3,ZC3HAV1,ZFAND2A |
| GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 72 | 19 | ACD,ATM,AURKB,DCP2,DKC1,EXOSC10,GAR1,HNRNPA1,HNRNPU,MAP2K7,NAF1,NEK2,NEK7,RFC1,SMG5,SMG7,TELO2,TERF2IP,TNKS |
| GO_REGULATION_OF_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 194 | 31 | ATMIN,ATXN2L,CDKL1,CEP120,CEP135,CEP76,CHMP4B,CHMP5,CNOT2,CNOT6,CNOT6L,CNTROB,DNM2,DRG1,EDN1,HNRNPU,LCP1,LRRTM2,MNS1,NUP62,PATL2,PLK4,RAB3GAP1,RNF4,SENP6,SMAD4,STAG1,STAG2,STAM,STX18,TCHP |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 432 | 49 | ABCA1,ABITRAM,ACTR3,AIDA,ATM,BAG4,BAIAP2L1,BID,BIN1,CAMSAP1,CDT1,CREB1,CUL4A,DDB1,DR1,DRG1,FAF1,FER,GTF2H2,HJURP,HSPA8,LCP1,MECP2,MTPN,NCKAP1,PAK1,PEX14,PPM1A,PSMC2,PSMC3,PSMC4,PSMC6,PTPN11,RICTOR,RIOK3,RNF4,RPA2,SAR1A,SENP6,SLAIN2,SLF1,TFIP11,TICAM1,TWF1,VDAC2,VPS35,WASH3P,WASH6P,WASHC1 |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 1604 | 118 | ABCA1,ABCA11P,ABCB7,ABCD4,ABCF1,AQP6,ARL6IP1,ATP5F1B,ATP5MG,ATP5PB,ATP6V0A2,ATP6V1G1,ATP6V1H,AZIN1,BIN1,CAPN10,CHERP,CLCC1,CLDN4,COA8,COX5A,CYC1,DNM2,DPP10,EDN1,FMR1,FXYD5,GABRG3,GALR2,GPR89A,GPR89B,GRPEL1,GRPEL2,GSK3A,HSPA8,IBTK,ITPR3,KCNK7,LYN,MAIP1,MCUR1,MTMR6,NDUFS7,NFE2L2,NIPA2,OAZ3,OR56A4,PEA15,PEX14,PHB2,PMPCB,PPIF,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,REM2,SEC61A2,SEC62,SEC63,SFXN5,SLC11A1,SLC16A4,SLC17A9,SLC19A2,SLC22A13,SLC25A19,SLC25A25,SLC25A26,SLC25A28,SLC25A32,SLC25A33,SLC25A38,SLC25A5,SLC26A7,SLC26A8,SLC30A5,SLC35B1,SLC35F1,SLC35F2,SLC38A9,SLC39A8,SLC3A2,SLC41A1,SLC4A1,SLC5A10,SLC66A1,SLC6A9,SLC7A11,SLC7A5P1,SLMAP,STOML2,TAP2,TIMM44,TIMM50,TSC1,UBB,UBC,UCP3,VDAC1,VDAC2,YES1 |
| GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1930 | 348 | 43 | AKAP8L,ANP32B,BAG3,BAG4,BAP1,C12orf4,CAPN10,CPSF6,CSNK2A2,CTDSPL2,DERL2,FER,GSK3A,LCP1,LYN,MTMR2,MYLK2,NDEL1,NUP153,NUP62,PAK1,PCM1,PDCD10,PPM1A,PTPN11,PTPN23,RAB21,RAN,RANGAP1,RBM22,RBM26,RBM27,RNF31,RUFY3,SAR1A,SEC24B,SFN,STX18,SUPT6H,TCF7L2,UBE2D3,VAMP7,XPO4 |
| GO_TRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 183 | 30 | AARSD1,ADAT2,ALKBH1,ALKBH8,CDKAL1,DDX1,DUS3L,EEF1E1,EXOSC10,EXOSC3,EXOSC9,GRSF1,HSD17B10,NARS1,NSUN3,POP7,PUS1,PUS7,QRSL1,RPUSD4,SEPHS1,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,WARS2,WDR4,ZBTB8OS |
| GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1930 | 433 | 49 | ACD,AIPL1,ANKRD11,ATM,AURKB,BAG3,BRCA2,CHMP4B,DCP2,DKC1,EXOSC10,FOXC1,GAR1,H4-16,HNRNPA1,HNRNPU,HUS1B,IQCB1,LTO1,LYZ,MAP2K7,MUC13,NAF1,NEK2,NEK7,NOTCH1,NSMCE2,PML,POLE,PTPN11,RAD51,RECQL4,RFC1,RIF1,RPA2,SMG1,SMG5,SMG7,SOD1,TELO2,TERF2IP,TFIP11,TMEM119,TNKS,TYRO3,USP7,YAP1,ZNF675,ZSCAN4 |
| GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1930 | 141 | 26 | AP2B1,CLTC,DVL3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SEC24B,SMURF1,WNT9B,ZNRF3 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1930 | 526 | 55 | ABCA1,ACTR3,ATM,ATMIN,BAG4,BAIAP2L1,BID,BIN1,CDT1,CEP120,CEP135,CLASP2,CNOT2,CNOT6,CNOT6L,CREB1,CUL4A,DDB1,DNM2,DRG1,EDN1,FAF1,FER,FMR1,GTF2H2,HGS,HSF1,LCP1,LRRTM2,MAP4K4,MECP2,MNS1,NCKAP1,NDEL1,NUP62,PAK1,PLK4,PSMC2,PSMC3,PSMC4,PSMC6,RAB3GAP1,RICTOR,RPA2,SLAIN2,SLF1,SRPX2,STAM,STX18,TSC1,VPS4A,WASF2,WASH3P,WASH6P,WASHC1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1247 | 98 | AKAP8,AKAP8L,ANKLE2,ARAF,ARRDC3,ATM,AXIN1,BAG4,BANK1,BRD4,BRMS1,CCNB1,CCNK,CCNT1,CCNT2,CDC6,CDK1,CDK5RAP3,CLCF1,CNOT9,CUL3,DAXX,DCUN1D2,DVL3,EDN1,FANCI,FANCM,FMR1,FXR1,GFRAL,GSK3A,HSF1,IQGAP3,JTB,KAT5,KAT7,KLB,KMT2A,LYN,MAP2K7,MAP4K4,MARCHF7,MASTL,MECP2,NMI,NOTCH1,NSD3,PAF1,PAK1,PAK2,PARP14,PDCD10,PEA15,PEF1,PHB2,PHF1,POMT2,PPP1R15A,PPP2R5D,PTPN11,RAB1A,RAB3GAP1,RAP2C,RCHY1,RICTOR,RIF1,RNF40,RPS6KA5,SART3,SIRT1,SLC11A1,SMAD4,SNW1,SOD1,SPDYA,STK10,TAB2,TADA2B,TELO2,TERF2IP,TICAM1,TMEM119,TNFRSF10A,TPX2,TRAF2,TRAF4,UBB,UBC,UBE2C,UBE2I,UBE2K,UBE3A,WDR48,XIAP,YES1,ZEB2,ZFP91,ZNF622 |
| GO_PROTEIN_ACYLATION | 0.0e+00 | 0.0e+00 | 1930 | 246 | 35 | ABHD17B,ACTL6A,ATF2,BRCA2,BRD1,CHEK1,CREBBP,DPF2,DR1,HAT1,ING3,KANSL1,KANSL2,KAT5,KAT7,KMT2A,MBIP,MECP2,MSL2,MSL3,NAA20,NAA25,NAA35,PPM1A,RPS6KA5,SET,SIRT1,SMAD4,SUPT7L,TADA1,TADA2B,TAF5L,TAF9B,TERF2IP,ZDHHC18 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 366 | 44 | AADAC,AGO2,ATM,ATXN3,AXIN1,BAG2,BAG3,CNOT6L,COP1,DDA1,FAF1,FBXO7,FMR1,GRSF1,GSK3A,HSF1,ITCH,KAT5,MFN2,NFE2L2,PABPC1,PFKFB3,PSMC1,PSMC2,PSMC4,PUM1,RAB3GAP1,RC3H1,RCHY1,RNF19B,RNF40,SIRT1,SMURF1,SUMO2,SUPV3L1,TICAM1,TSC1,UVRAG,VPS35,WAC,YTHDF2,YTHDF3,ZC3HAV1,ZFAND2A |
| GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME | 0.0e+00 | 0.0e+00 | 1930 | 83 | 20 | ACD,ATM,AURKB,BRCA2,CDCA5,CDK1,CDT1,CENPA,CENPQ,DKC1,LEMD2,MIS12,MTBP,RAD21,RCC2,RPA2,SLF1,TERF2IP,TNKS,WAPL |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1962 | 136 | AARSD1,ABCA1,ABCD4,ACER1,ACO2,ADIPOR1,AFP,AKR1C1,ALDH2,AMT,AS3MT,ATF4,ATP5F1B,ATP5MG,ATP5PB,AZIN1,BAAT,BCAN,BNIP2,CBR3,CDADC1,CHST3,CLN6,CLTC,COQ8A,CS,CTPS1,CYC1,DCK,DCTD,DDB1,DHDDS,DYRK2,ECI1,EDN1,EEF1E1,ENTPD7,ERO1B,FOXK2,GALR2,GLUD1,GMPPB,GMPS,GSK3A,GSR,HDLBP,HINT1,HKDC1,HMMR,HSD17B10,IDH3B,INPP5B,KPNB1,LIPC,LYRM4,MBD4,MECP2,MRPS36,MTHFD1,MTMR2,NAPRT,NARS1,NAXD,NDUFA9,NFKB1,NFYC,NME6,NT5C3A,NT5C3B,NUDT15,NUDT4,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OAZ3,PAPSS2,PDXDC1,PFKFB3,PLAA,PNPLA8,POFUT2,PPCDC,PRKAB1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTS,QRSL1,RAE1,RAN,RDH16,REXO2,RNASEH2B,RPIA,RRM1,SEPHS1,SIK1,SIRT1,SLC19A2,SLC22A13,SLC25A19,SLC25A32,SLC4A1,SLC52A2,SLC7A11,SOD1,SORD,STOML2,TGDS,TSTA3,UCP3,UGDH,UGT2B7,UNG,VDAC1,VNN3,WARS2 |
| GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1930 | 544 | 56 | AP2B1,C2CD3,CASP3,CLASP2,CLTC,DVL3,EDN1,FEM1B,FRZB,GNA13,GRSF1,HOXA11,KDM6A,KLF4,KRT16,LIN7C,MED1,MTHFD1,NOTCH1,PAK1,PDCD10,PHB2,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RBM15,RPS7,SEC24B,SIX4,SMAD4,SMURF1,TBR1,TBX3,TMED2,TSC1,WNT9B,YAP1,ZEB2,ZNRF3 |
| GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 0.0e+00 | 0.0e+00 | 1930 | 31 | 13 | ALYREF,BRD4,CCNK,CCNT1,CCNT2,CDK12,ELL,GTF2F1,PAF1,SCAF8,SUPT6H,THOC1,THOC5 |
| GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 0.0e+00 | 0.0e+00 | 1930 | 51 | 16 | ALYREF,BRD4,CCNK,CCNT1,CCNT2,CDK12,ELL,GTF2F1,HNRNPU,NELFA,PAF1,SCAF8,SUPT6H,THOC1,THOC5,ZNF326 |
| GO_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1930 | 250 | 35 | AP2B1,CLTC,DVL3,EDN1,FOXC1,HOXA11,HOXC11,MED1,NOTCH1,PHB2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SEC24B,SIX4,SMAD4,SMURF1,WNT9B,ZNRF3 |
| GO_REGULATION_OF_DNA_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1930 | 103 | 22 | ALYREF,CGAS,CHEK1,CLCF1,EXOSC3,H1-4,HELB,KPNA2,NSD2,PPP4C,PPP4R2,RAD51,RAD51AP1,RIF1,RPA2,SHLD1,SHLD2,SUPT6H,TERF2IP,THOC1,UBQLN4,ZSCAN4 |
| GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 0.0e+00 | 0.0e+00 | 1930 | 201 | 31 | ATF4,ATXN3,BAG3,CDK5RAP3,CUL3,DAXX,DDX11,DERL2,DNAJA1,DNAJB1,DNAJB14,FBXO6,GET3,GSK3A,HSF1,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,KLHDC3,MFN2,NFE2L2,POMT2,PPP1R15A,RNF126,SRPRB,SSR1,TATDN2,UBXN4,UFD1 |
| GO_PROTEIN_METHYLATION | 0.0e+00 | 0.0e+00 | 1930 | 178 | 29 | BRD4,DOT1L,EEF1AKMT2,EZH1,FBXO11,GSPT1,H1-4,KDM6A,KMT2A,KMT2B,KMT5A,MECP2,METTL21A,NSD2,NSD3,PAF1,PHF1,PRDM4,PWP1,RIF1,SETD4,SETDB1,SIRT1,SMAD4,SNRPB,SNW1,SUPT6H,TET3,ZNF335 |
| GO_PEPTIDYL_LYSINE_ACETYLATION | 0.0e+00 | 0.0e+00 | 1930 | 168 | 28 | ACTL6A,ATF2,BRCA2,BRD1,CHEK1,CREBBP,DPF2,DR1,HAT1,ING3,KANSL1,KANSL2,KAT5,KAT7,KMT2A,MBIP,MECP2,MSL2,MSL3,RPS6KA5,SET,SIRT1,SMAD4,SUPT7L,TADA1,TADA2B,TAF5L,TAF9B |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 0.0e+00 | 1930 | 1210 | 95 | ABCD4,ACTR3,ADIPOR1,ATP5F1B,BAG4,BTK,CACTIN,CAMK2G,CAPN2,CASP3,CD274,CLCF1,CNOT9,CREB1,CTBP2,CUL1,EDN1,FBXW11,FER,FOXC1,GPR75,GSK3A,HIPK1,HNRNPU,HSPA8,HSPA9,IL18RAP,IRAK3,KLF4,LCP1,LRRC70,MAP2K7,MAPK8,MED1,MRPL15,NFE2L2,NFKB1,NMI,OTUD4,PAK2,PARP14,PDCD10,PGGT1B,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PTPN23,RBM15,RBMX,RC3H1,REL,RIF1,RNF31,RO60,RPS6KA5,SIRT1,SLC11A1,SLC25A5,SMAD4,SNRPA1,SOD1,TAB2,TAX1BP1,TNIP2,TRAF2,TRAIP,TRIM56,TXLNA,UBB,UBC,UBE2K,YTHDF2,YTHDF3,YY1,ZC3H15,ZEB1,ZNF675 |
| GO_REGULATION_OF_GROWTH | 0.0e+00 | 0.0e+00 | 1930 | 680 | 64 | ACTL6A,ADIPOR1,ADNP2,ATAD3A,BAP1,BLZF1,BRMS1L,CCNB1,CCNB2,CDK1,CDK11A,CDKN2AIP,CREB1,CRLF3,DCAF1,DERL2,DNM2,E4F1,EDN1,EGLN2,EIF4G2,EXOSC4,EXOSC9,FGFR1OP,FOXC1,FRZB,GSK3A,HSF1,IFRD1,ING3,ITCH,ITSN2,KAT5,MTPN,NDEL1,NDUFS3,NME6,NOTCH1,PAK1,PAK2,PARP2,PLAA,PML,RAB21,RNF6,RUFY3,SFN,SIRT1,SIX4,SLC25A33,SMAD4,SMURF1,SOCS6,SOD1,SOX15,SPART,SUPV3L1,SYT1,TAF9B,TCHP,USP47,YAP1,YY1,ZNF639 |
| GO_TRANSLATIONAL_INITIATION | 0.0e+00 | 0.0e+00 | 1930 | 192 | 30 | AGO2,ALKBH1,ATF4,BANK1,DDX1,DENR,EIF1AD,EIF2A,EIF2B4,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF4B,EIF4G2,EIF5,FMR1,LTO1,MTIF2,PABPC1,PAIP1,PPP1R15A,RPL21,RPL22,RPS7,YTHDF2,YTHDF3 |
| GO_GAMETE_GENERATION | 0.0e+00 | 0.0e+00 | 1930 | 698 | 65 | AFP,ANKRD49,ATM,BCL2L2,BRCA2,CCNB1,CCNB1IP1,CDC25C,CELF1,CEP57,CFAP157,CIP2A,CSNK2A2,DAZAP1,DIAPH2,DMC1,DNAJA1,DNM2,FANCG,FOXC1,GGNBP2,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,ICA1L,INPP5B,KIF18A,KMT2B,MASTL,MCMDC2,MNS1,MSH4,NCAPH,NCAPH2,NLRP14,NOTCH1,NR2C2,NUP62,OAZ3,ODF2,PUM1,RACGAP1,RAI14,SIRT1,SLC26A8,SMAD4,SNRPA1,SOD1,SPDYA,SRPK1,TIAL1,TMEM119,TOP2A,TTC26,TYRO3,UBB,WDR48,YTHDF2,YY1,ZNF148,ZNF296 |
| GO_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1930 | 181 | 29 | AP2B1,CLASP2,CLTC,DVL3,PHB2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SEC24B,SIX4,SMURF1,WNT9B,ZNRF3 |
| GO_POSITIVE_REGULATION_OF_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 106 | 22 | AKAP8,AKAP8L,ATM,BRD4,CCNB1,FMR1,KAT7,KMT2A,MECP2,MIER1,NSD3,PAF1,PHF1,RIF1,RNF40,RPS6KA5,SART3,SETDB1,SIRT1,SMAD4,SNW1,TADA2B |
| GO_TISSUE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1930 | 670 | 63 | AP2B1,C2CD3,CASP3,CLASP2,CLTC,COL6A3,DVL3,EDN1,FEM1B,FOXC1,FRZB,GNA13,GRSF1,HOXA11,KDM6A,KDM6B,KLF4,KRT16,LIN7C,MATN1,MDM4,MED1,MTHFD1,MYLK2,NOTCH1,PAK1,PDCD10,PHB2,PML,POFUT2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RBM15,RPS7,SEC24B,SIX4,SMAD4,SMURF1,TBR1,TBX3,TMED2,TSC1,WNT9B,YAP1,ZEB2,ZNRF3 |
| GO_REGULATION_OF_CELL_CYCLE_ARREST | 0.0e+00 | 0.0e+00 | 1930 | 107 | 22 | ATM,BIN1,CCNB1,CCNK,CDC25C,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,MDM4,PML,SDE2,SFN,SLC25A33,TFDP2,UHRF2 |
| GO_NUCLEOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 184 | 29 | ACTR6,ANP32B,ANP32E,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,DAXX,GRWD1,H1-4,H2BC3,H4-16,HAT1,HJURP,HMGB2,HP1BP3,MIS18A,NAP1L1,NAP1L4,PAF1,RBBP4,SART3,SET,SPTY2D1,SUPT6H |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1930 | 872 | 75 | AIDA,AXIN1,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK1,CDK12,CDK5RAP3,CHORDC1,DAXX,DBNDD2,DGKZ,DNAJA1,DVL3,EDN1,FAF1,FBXO7,FGFR1OP,GFRAL,GGNBP2,HGS,HNRNPU,IBTK,IPO7,IQGAP3,IRAK3,JTB,KLF4,LYN,MAP2K7,MAP4K4,MBIP,MCPH1,NUP62,PAK1,PAK2,PDCD10,PEA15,PRKRIP1,PTPN11,RAP2C,RICTOR,SFN,SIRT1,SLC11A1,SMG8,SOCS6,SOD1,SPDYA,STK10,TAB2,TELO2,TNFRSF10A,TPX2,TRAF2,TRAF4,TSC1,UBB,UBC,UVRAG,VAV2,WASHC1,ZEB2,ZFP91,ZNF16,ZNF622,ZNF675 |
| GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 185 | 29 | ARAF,ATXN3,BAG2,COP1,DDA1,DERL2,FMR1,GSK3A,MARCHF7,NFE2L2,NUDT15,PSMC1,PSMC2,PSMC4,PSME2,RCHY1,RNF19B,RNF40,SENP1,SUMO2,TLK2,UBB,UBE2K,UBQLN4,UFL1,USP14,USP7,WAC,ZFAND2A |
| GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 80 | 19 | ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDCA5,CDT1,CUL3,DDX11,DYNC1LI1,ESPL1,HNRNPU,NSMCE2,PSMG2,RAD21,SLF1,TNKS,WAPL |
| GO_PEPTIDYL_LYSINE_METHYLATION | 0.0e+00 | 0.0e+00 | 1930 | 130 | 24 | BRD4,DOT1L,EEF1AKMT2,EZH1,H1-4,KDM6A,KMT2A,KMT2B,KMT5A,MECP2,METTL21A,NSD2,NSD3,PHF1,PWP1,RIF1,SETD4,SETDB1,SIRT1,SMAD4,SNW1,SUPT6H,TET3,ZNF335 |
| GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1930 | 28 | 12 | CCNB1,CDC6,CDT1,CUL3,DDX11,ESPL1,HNRNPU,NSMCE2,RAD18,RAD21,RCC2,SLF1 |
| GO_REGULATION_OF_TELOMERE_MAINTENANCE | 0.0e+00 | 0.0e+00 | 1930 | 81 | 19 | ACD,ATM,AURKB,DCP2,DKC1,EXOSC10,HNRNPA1,HNRNPU,MAP2K7,NAF1,NEK2,NEK7,PML,SMG1,SMG5,SMG7,TERF2IP,TNKS,USP7 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 1721 | 121 | ABCA1,ACAP2,ADIPOR1,AKAP8,AKR1C1,ATF4,ATP6V0A2,ATP6V1G1,ATP6V1H,AXIN1,BAG4,BAIAP2L1,BCL2L2,CAPN10,CAPN2,CASP3,CASP7,CCNA2,CDC6,CEP57,CHMP5,CLDN4,CNOT2,CNOT9,CPEB1,CREB1,CREBBP,CTDSPL2,CTSL,CYC1,DAXX,DDX11,DDX54,DNAJA1,DNM2,EDN1,EGLN2,EIF2B4,ELK1,FER,FGF22,FOXC1,FRS3,GNB1,GNRH1,GPR83,GSK3A,GTF2F1,HMGB2,HNRNPA1,HNRNPH1,HNRNPU,HSF1,KAT5,KIF18A,KLB,KLF4,LANCL2,LEMD2,LRIT3,LYN,MBD4,MCM7,MED1,MUS81,NCOR1,NDEL1,NFE2L2,NFKB1,NOTCH1,NR2C2,NSG1,NUCKS1,NUP62,OR56A4,PAK1,PARD3,PHB2,PHIP,PML,PPM1A,PTPN11,RAB14,RAB35,RAD51,RAN,RANGAP1,RBBP4,RBBP8,RNF4,RNF40,RNF6,SHCBP1,SIRT1,SLC25A33,SLC38A9,SMAD4,SMURF1,SNW1,SOD1,SORD,SPART,SRSF4,STRN3,TIAL1,TICAM1,TMEM108,TSC1,UBB,UBC,UBE2D3,UBE2I,UBE3A,UCP3,UFL1,VPS35,XIAP,YAP1,YES1,YY1,ZEB1 |
| GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER | 0.0e+00 | 0.0e+00 | 1930 | 188 | 29 | CCNB1,CDK1,CREB1,CREBBP,DR1,E2F3,GTF2F1,GTF2H2,MECP2,MED1,MED10,MED13,MED17,MED27,MED30,MED31,MED6,NOTCH1,NR2C2,NR2C2AP,PSMC2,PSMC3,PSMC4,PSMC6,SNW1,TAF2,TAF9B,TEAD4,YAP1 |
| GO_PROTEIN_TARGETING_TO_MITOCHONDRION | 0.0e+00 | 0.0e+00 | 1930 | 101 | 21 | BAG3,BAG4,BAP1,BID,CSNK2A2,FBXO7,GRPEL1,GRPEL2,GSK3A,MAIP1,MFN2,MTERF4,PMPCB,RNF31,SAMM50,TIMM10,TIMM10B,TIMM44,TIMM50,UBE2D3,UQCRC2 |
| GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 278 | 36 | AXIN1,CNOT2,CNOT9,CTBP2,DAXX,DDX54,DDX60,DNAJA1,EGLN2,GPATCH3,ITCH,KAT5,MED1,NCOR1,NPLOC4,PAK1,PHB2,PML,PUM1,PUM2,RAN,RIOK3,RNF4,RNF6,SIRT1,SNW1,STRN3,TAB2,UBB,UBC,UBE2I,UBE3A,UFD1,UFL1,XIAP,YAP1 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1930 | 853 | 73 | AFP,ANKRD49,ATM,BCL2L2,BRCA2,CASP3,CCNB1,CCNB1IP1,CDC25C,CELF1,CEP57,CFAP157,CIP2A,CSNK2A2,DAZAP1,DIAPH2,DMC1,DNAJA1,DNM2,EDN1,FANCG,FOXC1,GGNBP2,GNRH1,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,ICA1L,INPP5B,KIF18A,KMT2B,MASTL,MCMDC2,MED1,MNS1,MSH4,NCAPH,NCAPH2,NLRP14,NOTCH1,NR2C2,NUP62,OAZ3,ODF2,PTPN11,PUM1,RACGAP1,RAI14,SIRT1,SLC26A8,SMAD4,SNRPA1,SOD1,SP3,SPDYA,SRPK1,TIAL1,TMED2,TMEM119,TOP2A,TTC26,TYRO3,UBB,UBE2A,WDR48,YTHDF2,YY1,ZNF148,ZNF296 |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1930 | 737 | 66 | AIFM2,ANP32B,APH1A,ATF2,ATF4,ATM,BID,BIN1,BRMS1,C3orf38,CAPN10,CAPN2,CASP10,CASP3,CD274,COA8,CREB1,DAXX,DNAJA1,DNM2,E2F3,EEF1E1,ELK1,FAF1,FGD1,FRZB,GNA13,GSK3A,HSF1,ING3,KHDC1L,LYN,MAPK8,MELK,MFN2,MTCH1,NFKBID,NOTCH1,PAK2,PAWR,PEA15,PLAGL2,PML,PPIF,PPP2R1B,PPP3CC,PPP3R1,RBM10,RNPS1,RPS7,SAP30BP,SENP1,SFN,SIK1,SIRT1,SOD1,TFDP2,TNFRSF10A,TOP2A,TRAF2,UBB,UBC,UBE2M,UBE2Z,VAV2,ZNF622 |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 0.0e+00 | 0.0e+00 | 1930 | 499 | 51 | ABL2,ATG12,ATM,ATP6V0A2,ATP6V1G1,ATP6V1H,BAG3,CASP3,CHMP4B,CISD2,CLTC,CSNK2A2,EIF4G2,FBXO7,FOXK2,GABARAPL1,GSK3A,HGS,HSPA8,ILRUN,KAT5,LGALS8,MAPK8,MFN2,NSFL1C,PLAA,PRKAB1,RAB1A,RAB3GAP1,SIRT1,SLC38A9,SMURF1,SNX5,STAM,SUPT20H,TAB2,TICAM1,TLK2,TSC1,UBQLN4,USP30,UVRAG,VDAC1,VPS26A,VPS35,VPS37A,VPS4A,VPS51,VTI1A,WAC,WASHC1 |
| GO_CANONICAL_WNT_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 337 | 40 | AXIN1,CSNK1G1,CUL3,DVL3,FRZB,GID8,GSK3A,KDM6A,KLF4,NFKB1,NOTCH1,PFDN5,PPM1A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TCF7L2,TNKS,USP47,VPS35,WNT9B,XIAP,YAP1,ZNRF3 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 1454 | 106 | ACAP2,ADIPOR1,AKAP8,AKR1C1,ATF4,ATP6V0A2,ATP6V1G1,ATP6V1H,AXIN1,BAG4,BAIAP2L1,BCL2L2,CAPN10,CAPN2,CASP3,CASP7,CCNA2,CDC6,CEP57,CHMP5,CNOT2,CNOT9,CPEB1,CREB1,CREBBP,CTDSPL2,CTSL,DAXX,DDX11,DDX54,DNAJA1,DNM2,EDN1,EGLN2,ELK1,FER,FGF22,FOXC1,FRS3,GNB1,GSK3A,GTF2F1,HNRNPA1,HNRNPH1,HNRNPU,HSF1,KAT5,KIF18A,KLB,KLF4,LANCL2,LEMD2,LRIT3,LYN,MCM7,MED1,MUS81,NCOR1,NDEL1,NFE2L2,NFKB1,NOTCH1,NR2C2,NSG1,NUCKS1,NUP62,OR56A4,PAK1,PARD3,PHB2,PHIP,PML,PPM1A,PTPN11,RAB14,RAB35,RAD51,RAN,RANGAP1,RNF4,RNF6,SHCBP1,SIRT1,SLC25A33,SLC38A9,SMAD4,SMURF1,SNW1,SOD1,SPART,STRN3,TIAL1,TMEM108,TSC1,UBB,UBC,UBE2D3,UBE2I,UBE3A,UCP3,UFL1,VPS35,XIAP,YAP1,YES1,ZEB1 |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1930 | 1287 | 97 | ABL2,ACAP2,ADRM1,AGAP6,AHSA2P,ANKLE2,ANP32B,ARHGAP11B,ARHGAP19,ARL6IP1,BAG4,BCL2L12,BID,BIN1,BNIP2,CASP10,CD2BP2,CDK5RAP3,CLDN4,COA8,COL6A3,CPAMD8,DDX11,DENND1B,DEPDC1,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC9,DOCK2,DVL3,ELL,FGD1,GDI2,GNA13,GTF2H2,HMGB2,HNRNPU,HSCB,HSF1,IQGAP3,KHDC1L,KLF4,LIPC,LYN,MAP4K4,MAPK8,MASTL,MTCH1,NCAPH,NDEL1,PAK2,PCDH11X,PLAA,PML,PPIF,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R1B,PPP2R5D,PPP2R5E,PPP4R2,PPP6R1,PSMA3,PSME2,RAB11FIP2,RAB3GAP1,RACGAP1,RANGAP1,RASA2,RBM26,RCC2,RGPD6,RICTOR,SENP1,SERPINC1,SET,SFN,SIRT1,SOD1,SPINK5,TBC1D15,TBC1D22B,TMED2,TNFRSF10A,TRAF2,TSC1,UBE2Z,USP14,USP47,VAV2,XIAP,ZC3H15 |
| GO_DNA_DEPENDENT_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1930 | 146 | 25 | ALYREF,BRCA2,CDC6,CDK2,CDT1,CHTF18,DDX11,FANCM,GINS4,HELB,MCM7,MCMDC2,MMS22L,NUCKS1,ORC6,POLE,RAD51,RECQL,RECQL4,RFC1,RFWD3,RPA2,RPA4,STOML2,THOC1 |
| GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 146 | 25 | ACD,ATAD2,ATM,AURKB,BUB1,CCNB1,CDT1,DCP2,DYNC1LI1,ESPL1,EXOSC10,H1-4,HNRNPA1,HNRNPU,PHF1,PSMG2,RAD21,SET,SIRT1,SUPT6H,TERF2IP,TNKS,TOP2A,TRIP12,WAPL |
| GO_SEX_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1930 | 270 | 35 | AFP,ATM,BCL2L2,BRCA2,CASP3,CNOT9,CSDE1,DMC1,EIF2B4,FANCG,FOXC1,GNRH1,HMGB2,HOXA11,HOXA9,KIF18A,KMT2B,LHFPL2,MSH4,PTPN11,RNF38,RRM1,SF1,SIRT1,SIX4,SMAD4,SOD1,SOX15,TBX3,TYRO3,UBB,UBE3A,WDR48,WNT9B,ZFP42 |
| GO_RESPONSE_TO_LIGHT_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 311 | 38 | AIPL1,ATF4,AURKB,BRCA2,CASP3,CDC25A,CHEK1,COPS3,CREB1,CREBBP,DDB1,DNM2,DTL,ELK1,ERCC8,FBXL3,FMR1,GNB1,GRK7,GTF2H2,MAP2K7,MAPK8,MECP2,PER3,PML,POLK,RAD18,RBM4B,RO60,RRH,SDE2,SIK1,SIRT1,SLC7A11,UBE2A,USP1,USP47,YY1 |
| GO_CHROMOSOME_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1930 | 76 | 18 | ACTR3,ATM,CCNB1,CDCA5,CDT1,CENPQ,CHMP4B,CHMP5,CUL3,HNRNPU,KIF18A,KIF2C,KPNB1,MIS12,NDEL1,NUF2,NUP62,VPS4A |
| GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION | 0.0e+00 | 0.0e+00 | 1930 | 51 | 15 | CDCA5,CDT1,CUL3,EDN1,ESPL1,HNRNPU,NSFL1C,NSMCE2,NUP62,NUSAP1,PHB2,PHIP,SH2B1,SLF1,UBE2C |
| GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 183 | 28 | AXIN1,CUL3,DVL3,FRZB,GSK3A,NOTCH1,PFDN5,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TCF7L2,ZNRF3 |
| GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 220 | 31 | CAMSAP1,CEP120,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CLASP2,CLTC,DRG1,GSK3A,HDGFL3,HNRNPU,KIF18A,MCPH1,MECP2,MEMO1,NEK2,NSFL1C,NUP62,PAK1,PLK4,RAE1,RASSF1,RNF4,SENP6,SLAIN2,STAG1,STAG2,TPX2 |
| GO_MITOTIC_METAPHASE_PLATE_CONGRESSION | 0.0e+00 | 0.0e+00 | 1930 | 44 | 14 | CCNB1,CDCA5,CDT1,CHMP4B,CHMP5,CUL3,HNRNPU,KIF18A,KIF2C,KPNB1,MIS12,NUF2,NUP62,VPS4A |
| GO_CHROMATIN_REMODELING | 0.0e+00 | 0.0e+00 | 1930 | 172 | 27 | ACTL6A,ACTR6,ACTR8,ANP32E,BAZ2A,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,DAXX,DR1,EZH1,H4-16,HJURP,INO80B,KDM6A,KDM6B,MIS18A,PAK1,RBBP4,SPTY2D1,SUPT6H,TADA2B |
| GO_AMINE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 138 | 24 | AZIN1,MECP2,OAZ3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SLC7A11,VPS35 |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1930 | 974 | 79 | AIDA,ARAF,AXIN1,BANK1,BRAP,C3orf33,CDK1,CDK12,CDK5RAP3,CUL1,CUL3,DAXX,DNAJA1,DVL3,EDN1,FBXW11,FGF22,FRS3,GFRAL,HGS,HSF1,IQGAP3,IRAK3,ITCH,KLB,KLF4,LEMD2,LYN,MAP2K7,MAP4K4,MAPK6,MAPK8,MBIP,MED1,NCOR1,NFKB1,NOTCH1,NUP62,PABPN1,PAK1,PAK2,PDCD10,PEA15,PHB2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,RASA2,RHBDD3,SMAD4,SOD1,STK10,TAB2,TNIP2,TRAF2,TRAF4,UBB,UBC,WDR83,ZEB2,ZNF622,ZNF675 |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1930 | 1174 | 90 | AIDA,ANP32E,ARL6IP1,AURKB,BAG2,BAG4,BCL2L12,BIN1,BRMS1,CACTIN,CASP3,CD2BP2,CDK5RAP3,CFHR2,CHORDC1,COL6A3,CPAMD8,DBNDD2,DDX11,DNAJA1,DNAJB6,ELL,FAF1,FBXO7,FGFR1OP,FMR1,GALR2,GGNBP2,GLA,GSK3A,GTF2F1,HNRNPU,IBTK,ILRUN,IPO7,IRAK3,ITCH,KLF4,LYN,MAPK8,MASTL,MBIP,MED13,NEK2,NFKB1,NFKBID,NOTCH1,NUCKS1,NUP62,OAZ3,OR56A4,PAK2,PCDH11X,PEX14,PHB2,PPIF,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PRKRIP1,RBM26,RCC2,REM2,RLIM,RPS7,SERPINC1,SET,SFN,SIK1,SIRT1,SPINK5,SUMO3,TAX1BP1,TCF7L2,TFIP11,TMED2,TNKS,TRAIP,TSC1,UBE2Z,UFL1,USP14,USP47,USP7,WAPL,WASHC1,XIAP,ZNF675 |
| GO_RESPONSE_TO_UV | 0.0e+00 | 0.0e+00 | 1930 | 139 | 24 | ATF4,AURKB,BRCA2,CASP3,CDC25A,CHEK1,CREBBP,DDB1,DTL,ERCC8,FMR1,GTF2H2,MAP2K7,MAPK8,PML,POLK,RAD18,RO60,SDE2,SIRT1,UBE2A,USP1,USP47,YY1 |
| GO_DEPHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1930 | 479 | 49 | ACP7,ANKLE2,APTX,BAG4,CA3,CAMK2G,CD2BP2,CDC25A,CDC25C,CDK5RAP3,CTDSPL2,ELL,FBXW11,ILKAP,INPP5B,MASTL,MTMR2,MTMR6,NT5C3A,NT5C3B,PCDH11X,PFKFB3,PLPP5,PPM1A,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2CB,PPP2R1B,PPP2R5D,PPP2R5E,PPP3CC,PPP3R1,PPP4C,PPP4R2,PPP6R1,PTP4A1,PTP4A2,PTPN11,PTPN23,RBM26,RPAP2,SET,SMG5,SMG7,TIMM50,TSC1 |
| GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 436 | 46 | ABCA1,AKAP8L,ANKLE2,ARFGEF2,ARL6IP1,BAIAP2L1,BIN1,BLOC1S2,BLZF1,BNIP1,CCNB1,CCNB2,CDK1,CHMP4B,CHMP5,CLASP2,CREB1,DNM2,GET3,GOLGA8H,GORASP2,HGS,LEMD2,NDEL1,NPLOC4,NSFL1C,PDCD10,RAB18,RAB1A,RAB38,RAB3GAP1,RBSN,SLC4A1,SOD1,STAM,STX16,STX18,TJAP1,TMED2,TMED5,TMEM170A,VPS37A,VPS4A,VPS51,VTI1A,WASH3P |
| GO_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 1930 | 1442 | 104 | AP1G1,AP3B1,ATM,AZI2,BANK1,BTK,C12orf4,CASP3,CD226,CD274,CD3G,CGAS,CLCF1,CLEC4A,CRTC3,CTPS1,DCAF1,DGKZ,DOCK2,DPP7,DYNC1LI1,EDN1,EXOSC3,FBXO7,FER,GDI2,GLA,GNA13,GNB1,GNRH1,HOXA9,HSPA6,HSPA8,HSPH1,IGHV3-43,IL18RAP,ITFG2,ITPR3,JMJD6,KCMF1,KPNB1,LCP1,LYN,LYZ,MARCHF7,MICB,NAPRT,NCAPH2,NFKB1,NFKBID,NKAP,NSD2,PAK1,PAK2,PAWR,PKNOX1,PSMA2,PSMB7,PSMC2,PSMC3,PSMD1,PSMD12,PSMD2,PSMD6,PTPN11,RAB14,RAB18,RAP2C,RC3H1,RHBDD3,RIF1,RPL22,SART1,SH3KBP1,SHLD1,SHLD2,SLC11A1,SLC7A11,SMAD4,SOCS6,SOD1,SOX15,SP3,SPINK5,STK10,STOML2,SUCNR1,SUPT6H,TCF3,THBD,THOC1,TICAM1,TNIP2,TSC1,TUBB,TXLNA,TYRO3,UNG,VAMP7,VAPA,VAV2,YES1,ZEB1,ZNF335 |
| GO_BLASTOCYST_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1930 | 99 | 20 | ACTL6A,BRCA2,CAPN2,CCNB1IP1,CNOT2,CNOT3,COPS2,CUL3,GINS4,MFN2,NDEL1,NEK2,PSMC3,PSMC4,RBBP8,SBDS,SP3,SUPT6H,UBE2A,XAB2 |
| GO_CYTOPLASMIC_TRANSLATION | 0.0e+00 | 0.0e+00 | 1930 | 99 | 20 | CPEB1,DENR,DPH2,DPH5,DPH7,DRG1,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF5,FMR1,GSPT1,HSPA14,RPL22,YTHDF2,ZC3H15 |
| GO_RESPONSE_TO_OXIDATIVE_STRESS | 0.0e+00 | 0.0e+00 | 1930 | 453 | 47 | ADNP2,APTX,ATF4,BRF2,BTK,CA3,CAPN2,CASP3,CCNA2,CDK1,CDK2,COA8,DNM2,EDN1,ERCC8,FBXO7,FER,GSR,HSF1,IL18RAP,KDM6B,KLF4,KPNA4,MAPK8,MELK,MICB,NAPRT,NDUFS8,NFE2L2,NONO,NUDT15,OXR1,PAWR,PDCD10,PML,PPIF,PPP2CB,PSMB5,PYROXD1,SIRT1,SLC7A11,SOD1,TRAF2,TSC1,UBE3A,UCP3,ZNF622 |
| GO_CHROMATIN_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 165 | 26 | ANP32B,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,DAXX,GRWD1,H1-4,H2BC3,H4-16,HAT1,HJURP,HMGB2,HP1BP3,MIS18A,NAP1L1,NAP1L4,PAF1,RBBP4,SART3,SET,SPTY2D1 |
| GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1930 | 439 | 46 | AFP,ALKBH1,ATM,BCL2L2,BRCA2,CASP3,CSDE1,DAZAP1,DMC1,DNAJB6,EIF2B4,FANCG,FEM1B,FOXC1,GGNBP2,GNRH1,HMGB2,HOXA11,HOXA9,HSF1,KIF18A,KMT2B,MED1,MSH4,NOTCH1,PLK4,PTPN11,RBM15,RNF38,RRM1,SF1,SIRT1,SIX4,SMAD4,SOD1,SOX15,SP3,TBX3,TMED2,TYRO3,UBB,UBE3A,WDR48,WNT9B,ZFP42,ZNF568 |
| GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1930 | 203 | 29 | ATM,BID,CCNB1,CDC25C,CDC6,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CUL4A,FBXO7,KLF4,LSM11,MDM4,MTBP,PAF1,PHB2,PML,PSME2,RFWD3,RPA2,SFN,TFDP2,WEE1 |
| GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 166 | 26 | BAG4,HIPK1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RNF31,TAX1BP1,TRAF2,TRAIP,ZNF675 |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 567 | 54 | ABITRAM,ACTR3,ATMIN,BAG4,C2CD3,CCDC13,CDK1,CDKL1,CEP120,CEP135,CEP57,CEP72,CEP76,CEP89,CFAP157,CKAP5,CNTROB,DNM2,FBF1,FER,FGD1,FGFR1OP,FMR1,FOPNL,FXR1,FXYD5,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,IQCB1,MCIDAS,MNS1,NCKAP1,NDEL1,NEK2,NOTCH1,ODF2,PCM1,PLK4,PTPN23,RCC2,RO60,RSPH4A,SH2B1,TCHP,TTC26,TUBB,TWF1,VAV2,WASF2,WASHC1 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST | 0.0e+00 | 0.0e+00 | 1930 | 81 | 18 | ATM,CCNB1,CDC25C,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,CRLF3,MDM4,PML,SFN,TFDP2,UHRF2 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1930 | 1135 | 87 | ABCA1,ADIPOR1,ATF4,ATP6V0A2,ATP6V1G1,ATP6V1H,ATXN3,AUP1,BAIAP2L1,BCL2L2,CAPN10,CAPN2,CASP3,CASP7,CCNA2,CDC6,CDK1,CDK2,CGAS,CHMP5,CPEB1,CREB1,CYC1,DAXX,DDX1,DDX11,DERL2,DNAJB14,DNM2,ECPAS,EDN1,EIF2B4,FBXO2,FBXO6,FER,FMR1,GNB1,GNRH1,GSK3A,HNRNPL,HSF1,HSP90B2P,IRAK3,KAT7,KLF4,LYN,NDEL1,NFE2L2,NFKB1,NOTCH1,NPLOC4,NSG1,NUCKS1,OR56A4,PAK1,PEA15,PHIP,POMT2,PQBP1,PSMB2,PSMC6,PTPN11,RAD51,RANGAP1,RBBP4,RIOK3,RNF40,SIRT1,SLC25A33,SLC38A9,SLC3A2,SOD1,SRSF4,THBD,TICAM1,TMUB2,TRAF2,TSC1,UBE3A,UBXN4,UBXN8,UCP3,UFD1,UFL1,USP14,VPS35,ZEB1 |
| GO_NEURON_DEATH | 0.0e+00 | 0.0e+00 | 1930 | 353 | 40 | ALKBH1,AP2B1,ATF2,ATF4,ATM,BID,BTBD10,CAPN2,CASP3,CD200R1,CHMP4B,CLCF1,CREB1,DAXX,EGLN2,ELK1,FBXO7,GFRAL,GPR75,GSK3A,HSF1,MECP2,NAE1,NONO,OXR1,PARP2,PSMC1,REL,SET,SIRT1,SIX4,SLC7A11,SOD1,TRAF2,TSC1,TYRO3,UBB,UBE2M,VPS35,XIAP |
| GO_KINETOCHORE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1930 | 21 | 10 | CDT1,CENPA,CENPK,CENPT,CENPW,MIS12,NUF2,RNF4,SENP6,SMC4 |
| GO_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE | 0.0e+00 | 0.0e+00 | 1930 | 33 | 12 | ABRAXAS2,AURKB,CCNB1,CDT1,HNRNPU,KIF2C,KNSTRN,MIS12,NEK2,NUF2,RACGAP1,RCC2 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 1930 | 82 | 18 | BCL2L12,BID,CGAS,HELB,HSF1,MARCHF7,RIF1,SHLD1,SHLD2,SIRT1,TAF9B,TFIP11,THOC1,THOC5,TRIP12,UBQLN4,USP47,YJU2 |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 1016 | 80 | AFP,AGO2,ANKRD49,ATM,BCL2L2,BRCA2,CAPN2,CCNB1,CCNB1IP1,CDC25C,CDK1,CELF1,CEP57,CFAP157,CIP2A,CLDN4,CSNK2A2,DAZAP1,DIAPH2,DMC1,DNAJA1,DNM2,EDN1,FANCG,FOXC1,GGNBP2,GNRH1,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,ICA1L,INPP5B,KIF18A,KMT2B,LHFPL2,MASTL,MCMDC2,MED1,MNS1,MSH4,NCAPH,NCAPH2,NLRP14,NOTCH1,NR2C2,NUP62,OAZ3,ODF2,PUM1,RACGAP1,RAI14,SIRT1,SLC26A8,SMAD4,SNRPA1,SOD1,SP3,SPDYA,SRPK1,THBD,TIAL1,TMED2,TMEM119,TOP2A,TTC26,TYRO3,UBB,UBE2A,UBE3A,UBXN8,VDAC2,WDR48,YTHDF2,YY1,ZNF148,ZNF296 |
| GO_VIRAL_LIFE_CYCLE | 0.0e+00 | 0.0e+00 | 1930 | 328 | 38 | CCNK,CDK1,CHMP4B,CHMP5,CTBP2,DDB1,FMR1,ILF3,ITCH,KPNA2,KPNB1,NOTCH1,NUCKS1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PABPC1,PCBP2,PML,RAB1A,RAE1,RAN,SETDB1,SLC52A2,SRPK1,TOP2A,TYRO3,UBB,UBC,UVRAG,VAPA,VPS37A,VPS4A,ZC3HAV1,ZNF639 |
| GO_CENTROMERE_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1930 | 56 | 15 | CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,H4-16,HJURP,MIS12,MIS18A,RBBP4,RNF4,SENP6 |
| GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 314 | 37 | AZIN1,CDK5RAP3,CHMP4B,CRTC3,CSNK2A2,DERL2,DHX34,DKC1,EIF4G2,FMR1,FOXK2,GSK3A,HNRNPU,IRAK3,MARCHF7,MDM4,MTMR2,NAF1,PABPC1,PAIP1,PDCL3,PML,RBM10,RPS7,SENP1,SLC11A1,TAB2,TENT4A,TLK2,TSC1,UBQLN4,USP14,USP30,USP7,VPS35,WAC,WASHC1 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1930 | 259 | 33 | CDK5RAP3,CHMP4B,CSNK2A2,DERL2,DHX34,DKC1,EIF4G2,FMR1,FOXK2,GSK3A,HNRNPU,MARCHF7,MTMR2,NAF1,PABPC1,PAIP1,PDCL3,PML,RBM10,RPS7,SENP1,SLC11A1,TAB2,TENT4A,TLK2,TSC1,UBQLN4,USP14,USP30,USP7,VPS35,WAC,WASHC1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 1930 | 135 | 23 | ARRDC3,AXIN1,CDK5RAP3,CUL3,DCUN1D2,FANCI,FANCM,GSK3A,MARCHF7,MASTL,NMI,PEF1,RAB1A,RCHY1,RNF40,SART3,TICAM1,UBB,UBE2C,UBE2I,UBE3A,WDR48,XIAP |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1930 | 791 | 67 | ADIPOR1,BAG4,CACTIN,CAMK2G,CASP3,CLCF1,CNOT9,CUL1,EDN1,FBXW11,FER,FOXC1,GPR75,HIPK1,HSPA8,HSPA9,IL18RAP,IRAK3,LCP1,MED1,NFKB1,NMI,OTUD4,PAK2,PARP14,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,RBM15,RNF31,RPS6KA5,SIRT1,SMAD4,SNRPA1,SOD1,TAB2,TAX1BP1,TNIP2,TRAF2,TRAIP,TXLNA,UBB,UBC,UBE2K,YTHDF2,YTHDF3,ZC3H15,ZEB1,ZNF675 |
| GO_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 0.0e+00 | 0.0e+00 | 1930 | 433 | 45 | ATF2,BRMS1,BTK,C3orf33,CACTIN,CDK5RAP3,CREBZF,CRTC3,EDN1,FAF1,FER,IL18RAP,IRAK3,ITCH,KLF4,LRRFIP1,MAPK8,MED13,MTPN,NFKB1,NFKBID,PEX14,PHB2,PPRC1,RLIM,RNF25,RNF31,RPS6KA5,SIK1,SIRT1,TAB2,TAX1BP1,TCF3,TCF7L2,TERF2IP,TICAM1,TRAF2,TRAF5,TRAIP,UBB,UBC,UBE2I,UFL1,USP7,ZNF675 |
| GO_DNA_GEOMETRIC_CHANGE | 0.0e+00 | 1.0e-07 | 1930 | 114 | 21 | CHTF18,CUL4A,DDB1,DDX1,DDX11,ERCC8,GINS4,GTF2H2,HELB,HMGB2,IGHMBP2,MCM7,RAD51,RAD54L,RAD54L2,RECQL,RECQL4,SUPV3L1,TOP2A,UBB,UBC |
| GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1930 | 125 | 22 | ACD,ATM,CGAS,DCP2,DNAJC2,EXOSC10,H1-4,HELB,HNRNPA1,HNRNPU,HSF1,KMT2A,RIF1,SHLD1,SHLD2,TERF2IP,TFIP11,THOC1,TNKS,TRIP12,UBQLN4,ZSCAN4 |
| GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 1.0e-07 | 1930 | 481 | 48 | ATM,BANK1,BTK,CACTIN,CASP3,CD200R1,CD274,CUL4A,DPF2,FBXO7,FER,GNRH1,GPATCH3,H4-16,HOXA9,HSPA9,ILRUN,IRAK3,ITCH,LPXN,LYN,MARCHF7,MICB,N4BP2L2,NFE2L2,NFKBID,NMI,NOTCH1,NPLOC4,OTUD4,PAF1,PARP14,PAWR,PCBP2,PSMA1,RBM15,RC3H1,RHBDD3,RIOK3,SOCS6,SPINK5,THOC1,TICAM1,TYRO3,UFD1,YTHDF2,YTHDF3,ZNF675 |
| GO_METAPHASE_PLATE_CONGRESSION | 0.0e+00 | 1.0e-07 | 1930 | 57 | 15 | CCNB1,CDCA5,CDT1,CENPQ,CHMP4B,CHMP5,CUL3,HNRNPU,KIF18A,KIF2C,KPNB1,MIS12,NUF2,NUP62,VPS4A |
| GO_SEXUAL_REPRODUCTION | 0.0e+00 | 1.0e-07 | 1930 | 847 | 70 | AFP,ANKRD49,ATM,BCL2L2,BRCA2,CCNB1,CCNB1IP1,CDC25C,CDK1,CELF1,CEP57,CFAP157,CIP2A,CSNK2A2,DAZAP1,DIAPH2,DMC1,DNAJA1,DNM2,FANCG,FOXC1,GGNBP2,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,ICA1L,INPP5B,KIF18A,KMT2B,LHFPL2,MASTL,MCMDC2,MNS1,MSH4,NCAPH,NCAPH2,NLRP14,NOTCH1,NR2C2,NUP62,OAZ3,ODF2,PUM1,RACGAP1,RAI14,SIRT1,SLC26A8,SMAD4,SNRPA1,SOD1,SPDYA,SRPK1,TIAL1,TMEM119,TOP2A,TTC26,TYRO3,UBB,UBE3A,UBXN8,VDAC2,WDR48,YTHDF2,YY1,ZNF148,ZNF296 |
| GO_MALE_GAMETE_GENERATION | 0.0e+00 | 1.0e-07 | 1930 | 562 | 53 | ANKRD49,ATM,BCL2L2,BRCA2,CCNB1,CCNB1IP1,CDC25C,CEP57,CFAP157,CIP2A,CSNK2A2,DAZAP1,DMC1,DNAJA1,DNM2,FANCG,GGNBP2,GOLGA3,GORASP2,HMGB2,HOXA11,HOXA9,HSF1,HSF2,ICA1L,INPP5B,KIF18A,MCMDC2,MNS1,MSH4,NLRP14,NOTCH1,NR2C2,NUP62,OAZ3,ODF2,PUM1,RACGAP1,RAI14,SIRT1,SLC26A8,SMAD4,SNRPA1,SOD1,SPDYA,SRPK1,TMEM119,TTC26,TYRO3,UBB,WDR48,YY1,ZNF296 |
| GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | 0.0e+00 | 1.0e-07 | 1930 | 223 | 30 | AFP,ATM,BCL2L2,BRCA2,CASP3,CSDE1,DMC1,EIF2B4,FANCG,FOXC1,GNRH1,HMGB2,HOXA11,HOXA9,KIF18A,KMT2B,LHFPL2,MSH4,RNF38,RRM1,SF1,SIRT1,SIX4,SMAD4,SOD1,SOX15,UBB,UBE3A,WDR48,ZFP42 |
| GO_MITOTIC_CHROMOSOME_CONDENSATION | 0.0e+00 | 1.0e-07 | 1930 | 17 | 9 | AKAP8,AKAP8L,CDCA5,NCAPH,NCAPH2,NUSAP1,PHF13,SMC4,TENT4A |
| GO_HISTONE_METHYLATION | 0.0e+00 | 1.0e-07 | 1930 | 138 | 23 | BRD4,DOT1L,EZH1,H1-4,KDM6A,KMT2A,KMT2B,KMT5A,MECP2,NSD2,NSD3,PAF1,PHF1,PRDM4,PWP1,RIF1,SETDB1,SIRT1,SMAD4,SNW1,SUPT6H,TET3,ZNF335 |
| GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 0.0e+00 | 1.0e-07 | 1930 | 162 | 25 | ATF4,ATXN3,BAG3,CDK5RAP3,CUL3,DAXX,DDX11,DERL2,DNAJB14,GET3,GSK3A,HSF1,HSPA14,HSPA6,HSPA8,HSPA9,KLHDC3,NFE2L2,POMT2,PPP1R15A,RNF126,SRPRB,SSR1,TATDN2,UFD1 |
| GO_CELLULAR_RESPONSE_TO_LIPID | 0.0e+00 | 1.0e-07 | 1930 | 615 | 56 | ABCA1,ABL2,ADNP2,AKAP8,ATM,AXIN1,BCL2L2,CACTIN,CAPN2,CCNA2,CCNB1,CD274,CHMP5,CNOT2,CNOT9,CREB1,DAXX,DDX54,DNAJA1,EDN1,EGLN2,ELK1,GNB1,HMGB2,HNRNPU,HSF1,KAT5,KIF18A,KLF4,LANCL2,LYN,MAPK8,MED1,NCOR1,NFKB1,NFKBIB,NR2C2,PABPN1,PAF1,PAK1,PHB2,PLAA,RAN,RNF4,RNF6,SIRT1,SNW1,STRN3,TICAM1,TNIP2,UBE2I,UBE3A,UFL1,WNT9B,YAP1,YES1 |
| GO_CENTROSOME_DUPLICATION | 0.0e+00 | 1.0e-07 | 1930 | 67 | 16 | BRCA2,C2CD3,CDK2,CEP120,CEP135,CEP72,CEP76,CHMP4B,CHMP5,CHORDC1,CKAP5,CNTROB,KIAA0753,NUP62,PLK4,WDR62 |
| GO_CELLULAR_RESPONSE_TO_RADIATION | 0.0e+00 | 1.0e-07 | 1930 | 187 | 27 | AIPL1,ATF4,ATM,AURKB,CDC25A,CHEK1,CREBBP,DDB1,DNM2,ELK1,FMR1,GNB1,GRK7,HSF1,INTS7,NUCKS1,POLK,RAD1,RAD51,RAD51AP1,RRH,SDE2,SIRT1,TLK2,USP47,YAP1,YY1 |
| GO_TRNA_PROCESSING | 0.0e+00 | 1.0e-07 | 1930 | 128 | 22 | ADAT2,ALKBH1,ALKBH8,CDKAL1,DDX1,DUS3L,GRSF1,HSD17B10,NSUN3,POP7,PUS1,PUS7,RPUSD4,SEPHS1,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,WDR4,ZBTB8OS |
| GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1930 | 337 | 38 | AARSD1,AMT,AZIN1,BAAT,CTPS1,EEF1E1,ERO1B,GLUD1,GMPS,HSD17B10,MECP2,MTHFD1,NARS1,OAZ3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTS,QRSL1,SEPHS1,SLC7A11,WARS2 |
| GO_GOLGI_VESICLE_TRANSPORT | 0.0e+00 | 1.0e-07 | 1930 | 367 | 40 | AP1G1,ARCN1,ARFGEF2,BLZF1,BNIP1,CNIH1,CUL3,DCTN4,DCTN5,DCTN6,DNM2,DYNC1LI1,ERGIC2,ERGIC3,GOLGA3,GOSR1,KIF18A,KIF2C,KLHL21,PEF1,PPP6R1,RAB14,RAB1A,RACGAP1,RBSN,RER1,SAR1A,SCAMP3,SCYL1,SEC24B,SEC24C,STX18,TMED2,TMED5,TRAPPC10,UVRAG,VAMP7,VAPA,VPS51,VTI1A |
| GO_NON_RECOMBINATIONAL_REPAIR | 0.0e+00 | 1.0e-07 | 1930 | 97 | 19 | ATM,BABAM1,ERCC8,H4-16,HSF1,KAT5,KDM2A,NSD2,PAXX,POLL,RBBP8,RIF1,RNF138,SHLD1,SHLD2,TFIP11,UIMC1,UVRAG,XRCC4 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 1.0e-07 | 1930 | 1698 | 115 | ABCA1,ABL2,ADIPOR1,ADNP2,AKAP8,AKR1C1,APTX,ATF2,ATF4,ATM,ATP6V0A2,ATP6V1G1,ATP6V1H,BAIAP2L1,BCL2L2,BTK,CA3,CACTIN,CAPN10,CAPN2,CASP3,CCNA2,CCNB1,CD274,CDC6,CDK1,CDK2,CDT1,CHMP5,CLDN4,COA8,CPEB1,CREB1,CYC1,DDX11,DNM2,EDN1,EEF1B2,EIF2B4,ELK1,FER,GDAP2,GNB1,GNRH1,GSK3A,HMGB2,HNRNPL,HSF1,IL18RAP,IRAK3,KAT5,KAT7,KDM6B,KIF18A,KLF4,KPNA4,LANCL2,LYN,MAPK8,MBD4,MED1,MICB,NDEL1,NDUFA9,NFE2L2,NFKB1,NFKBIB,NOTCH1,NSG1,NUCKS1,NUDT15,OR56A4,OXR1,PABPN1,PAF1,PAK1,PAWR,PDCD10,PHB2,PHIP,PLAA,PPIF,PPP2CB,PTPN11,RAB11FIP2,RAD51,RANGAP1,RBBP4,RBBP8,RNF40,SETDB1,SIRT1,SLC11A1,SLC25A33,SLC38A9,SNW1,SOD1,SRSF4,STRN3,TAB2,TCF7L2,THBD,TICAM1,TNIP2,TRAF2,TSC1,UBE3A,UCP3,UFL1,VPS35,WNT9B,YAP1,YES1,YY1,ZEB1 |
| GO_REGULATION_OF_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1930 | 153 | 24 | ARAF,AXIN1,COP1,CSNK2A2,DDA1,GSK3A,NFE2L2,PDCL3,PML,RCHY1,RNF19B,RPS7,SENP1,SMURF1,SUMO2,TLK2,UBE2K,UBE3A,UBQLN4,UFL1,USP14,USP7,WAC,ZFAND2A |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 1.0e-07 | 1930 | 655 | 58 | ACD,ARRDC3,AURKB,AXIN1,CCNB1,CCNK,CCNT1,CCNT2,CDC6,CDK1,CHTF18,DAXX,DCUN1D2,DGKZ,DKC1,DVL3,EDN1,GFRAL,GSK3A,IQGAP3,JTB,KLF4,LYN,MAP2K7,MAP4K4,MASTL,NAF1,NEK2,NEK7,PABPN1,PAK1,PAK2,PDCD10,PEA15,PTPN11,RAB1A,RICTOR,SIRT1,SLC11A1,SOD1,SPDYA,STK10,TAB2,TELO2,TNFRSF10A,TNKS,TPX2,TRAF2,TRAF4,UBB,UBC,UBE2C,UBE2I,VAV2,ZEB2,ZFP91,ZNF16,ZNF622 |
| GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 1930 | 216 | 29 | AXIN1,CUL3,DVL3,FRZB,GSK3A,HIC1,NOTCH1,PFDN5,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TCF7L2,ZNRF3 |
| GO_HISTONE_EXCHANGE | 0.0e+00 | 1.0e-07 | 1930 | 60 | 15 | ACTR6,ANP32E,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,H4-16,HJURP,MIS18A,RBBP4,SPTY2D1 |
| GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | 0.0e+00 | 1.0e-07 | 1930 | 191 | 27 | ANP32B,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,DAXX,GRWD1,H1-4,H2BC3,H4-16,HAT1,HJURP,HMGB2,HP1BP3,MIS18A,NAP1L1,NAP1L4,PAF1,RBBP4,SART3,SET,SPTY2D1,TLK2 |
| GO_MEMBRANE_DOCKING | 0.0e+00 | 1.0e-07 | 1930 | 179 | 26 | C2CD3,CDK1,CEP135,CEP57,CEP72,CEP76,CEP89,CKAP5,CTBP2,FBF1,FGFR1OP,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,IQCB1,NEK2,ODF2,PCM1,PLK4,RAB15,STX16,SYT1,TUBB |
| GO_VESICLE_ORGANIZATION | 0.0e+00 | 2.0e-07 | 1930 | 330 | 37 | ABCA1,AP1G1,AP3B1,ARFGEF2,BLOC1S2,CHMP4B,CHMP5,CNIH1,CREB1,CUL3,DNM2,GOSR1,HGS,KLHL21,PEF1,PPP6R1,RAB14,RAB1A,RAB38,SAR1A,SEC24B,SEC24C,SNX11,STAM,STX16,SYT1,TAP2,TMED2,TRAPPC10,UVRAG,VAMP7,VAPA,VPS37A,VPS4A,VTI1A,WASH3P,ZEB2 |
| GO_CELL_GROWTH | 0.0e+00 | 2.0e-07 | 1930 | 483 | 47 | ADIPOR1,ADNP2,ATAD3A,BAP1,BLZF1,CDK11A,CDKN2AIP,CRLF3,DERL2,DNM2,EDN1,EGLN2,EIF4G2,EXOSC4,EXOSC9,FGFR1OP,FRZB,GSK3A,IFRD1,ITCH,ITSN2,MTPN,NDEL1,NDUFS3,NME6,PAK1,PARP2,PLAA,PML,RAB21,RNF6,RUFY3,SFN,SIRT1,SLC25A33,SMAD4,SMURF1,SPART,SUPV3L1,SYT1,TAF9B,TCHP,TMEM108,USP47,YY1,ZEB2,ZNF639 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 0.0e+00 | 2.0e-07 | 1930 | 111 | 20 | ADRM1,ALYREF,BRD4,CCNK,CCNT1,CCNT2,CDK12,EAF1,ELL,ELOA,GTF2F1,GTF2H2,HNRNPU,NELFA,PAF1,SCAF8,SUPT6H,THOC1,THOC5,ZNF326 |
| GO_HOMOLOGOUS_RECOMBINATION | 0.0e+00 | 2.0e-07 | 1930 | 53 | 14 | ATM,CCNB1IP1,DMC1,FANCM,KLHDC3,MCMDC2,MND1,MSH4,MUS81,PSMC3IP,RAD21,RAD51,RAD54L,TOP2A |
| GO_INTERSTRAND_CROSS_LINK_REPAIR | 0.0e+00 | 2.0e-07 | 1930 | 53 | 14 | FANCG,FANCI,FANCM,MUS81,NUCKS1,RAD51,RAD51AP1,RFWD3,RPA2,UBB,UBC,UBE2T,USP1,WDR48 |
| GO_REGULATION_OF_PROTEIN_STABILITY | 0.0e+00 | 2.0e-07 | 1930 | 288 | 34 | APTX,BAG2,BAG3,CASP3,CDKN2AIP,COA8,CREB1,CREBBP,CUL3,DVL3,FBXL3,FBXO7,FBXW11,HSP90AA2P,HSP90AA4P,HSP90AB4P,HSPA8,MARCHF7,MDM4,PDCD10,PDCL3,PER3,PHB2,QRSL1,RPS7,SIRT1,TAF9B,TBRG1,TELO2,TNIP2,TSC1,USP3,USP7,VPS35 |
| GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 0.0e+00 | 2.0e-07 | 1930 | 288 | 34 | ATF4,ATXN3,AUP1,CDK5RAP3,DDX11,DERL2,DNAJB14,ECPAS,FBXO2,FBXO6,GET3,GORASP2,GSK3A,HSP90B2P,KLHDC3,NFE2L2,NPLOC4,PML,POMT2,PPP1R15A,PPP2CB,PSMC6,SIRT1,SRPRB,SSR1,TATDN2,TMUB2,TRAF2,UBE2K,UBXN4,UBXN8,UFD1,UFL1,USP14 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 2.0e-07 | 1930 | 532 | 50 | ACO2,AIFM2,ALDH2,ATP5F1B,ATP5MG,ATP5PB,BID,CCNB1,CDK1,COA6,COA8,COX5A,CS,CYC1,DYRK2,FOXK2,GLRX3,GSK3A,GSR,HKDC1,IDH3B,MECP2,MTFR2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,NRF1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PFKFB3,PHB2,PPIF,PPP1R2,RAE1,RDH16,RPIA,SLC25A25,SLC25A33,SLC4A1,STOML2,TSTA3,UQCRC2,UQCRH |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 0.0e+00 | 2.0e-07 | 1930 | 207 | 28 | ANP32B,BAG3,BAP1,CAPN10,CPSF6,CSNK2A2,CTDSPL2,GSK3A,MTMR2,PAK1,PCM1,PDCD10,PPM1A,PTPN23,RAB21,RAN,RBM22,RBM26,RBM27,RNF31,RUFY3,SAR1A,SFN,STX18,TCF7L2,UBE2D3,VAMP7,XPO4 |
| GO_CYTOKINESIS | 0.0e+00 | 2.0e-07 | 1930 | 170 | 25 | ACTR3,AURKB,BRCA2,CDC6,CENPA,CEP55,CHMP4B,CHMP5,CKAP2,CNTROB,CSPP1,CUL3,ESPL1,INCENP,JTB,KLHL21,MYO19,NUP62,NUSAP1,PLK4,PRC1,RAB35,RACGAP1,UVRAG,VPS4A |
| GO_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 0.0e+00 | 2.0e-07 | 1930 | 62 | 15 | ACD,ATM,AURKB,DCP2,DKC1,EXOSC10,HNRNPA1,HNRNPU,MAP2K7,NAF1,NEK2,NEK7,SMG5,SMG7,TNKS |
| GO_HISTONE_PHOSPHORYLATION | 0.0e+00 | 2.0e-07 | 1930 | 38 | 12 | AKAP8,AKAP8L,ATM,AURKB,CCNA2,CCNB1,CDK1,CDK2,CHEK1,DCAF1,FMR1,RPS6KA5 |
| GO_LYMPHOCYTE_ACTIVATION | 0.0e+00 | 2.0e-07 | 1930 | 736 | 62 | AP1G1,AP3B1,ATM,AZI2,BANK1,BTK,CASP3,CD274,CD3G,CGAS,CLCF1,CLEC4A,CTPS1,DCAF1,DOCK2,EXOSC3,FBXO7,GNRH1,HSPH1,IGHV3-43,ITFG2,JMJD6,LCP1,LYN,MARCHF7,MICB,NCAPH2,NFKBID,NKAP,NSD2,PAK1,PAK2,PAWR,PKNOX1,PTPN11,RC3H1,RHBDD3,RIF1,RPL22,SART1,SH3KBP1,SHLD1,SHLD2,SLC11A1,SOCS6,SOD1,SP3,SPINK5,STOML2,SUPT6H,TCF3,THOC1,TICAM1,TNIP2,TSC1,TXLNA,TYRO3,UNG,VAMP7,YES1,ZEB1,ZNF335 |
| GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 2.0e-07 | 1930 | 408 | 42 | AATF,BCL2L12,BCL2L2,BID,COA8,CSNK2A2,DNAJA1,FAF1,FEM1B,GFRAL,GSK3A,HMGB2,HNRNPK,MAPK8,MARCHF7,NDUFS3,NFE2L2,NONO,PAK2,PEA15,PHIP,PLAGL2,PML,PPIF,PPP2R1B,PPP3CC,PPP3R1,RPS7,SFN,SIRT1,SLC25A5,SOD1,TAF9B,TCF7L2,TFDP2,TNFRSF10A,TRAF2,UBB,USP47,VDAC2,YAP1,ZC3HC1 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 2.0e-07 | 1930 | 534 | 50 | ABITRAM,ABL2,ACTR3,BAG4,BAIAP2L1,BIN1,CAMSAP1,CAPN2,CEP120,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,CKAP2,CLASP2,CLTC,DRG1,EDN1,FER,GSK3A,HDGFL3,HNRNPU,KIF18A,MCPH1,MECP2,MTPN,NCKAP1,NEK2,NSFL1C,NUP62,PAK1,PLK4,RAE1,RASSF1,RICTOR,RND3,RNF4,SENP6,SLAIN2,SMAD4,STAG1,STAG2,TPX2,TSC1,TWF1,WASF2,WASH3P,WASH6P,WASHC1 |
| GO_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS | 0.0e+00 | 2.0e-07 | 1930 | 38 | 12 | AKAP8L,ANP32B,BAG3,CTDSPL2,PPM1A,PTPN11,RANGAP1,RBM22,SFN,SUPT6H,TCF7L2,XPO4 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 2.0e-07 | 1930 | 1037 | 79 | ABHD17B,AKAP8L,ANP32B,AP2B1,ATAD1,BAG3,BAG4,BANK1,BAP1,BID,CAPN10,CD200R1,CD274,CDCA5,CDK1,CDK5RAP3,CDT1,CENPQ,CEP120,CEP135,CEP72,CLTC,CSNK2A2,CTDSPL2,DERL2,DKC1,DNAJA1,DNAJB6,DPP10,DVL3,GLUD1,GSK3A,HSPA8,ILRUN,ITPR3,KAT7,LCP1,LYN,LZTFL1,MAPK8,NDEL1,NSD2,NSFL1C,NUP62,OTUD7B,PAK1,PCM1,PDCD10,PML,PPM1A,PPP3CC,PPP3R1,PTPN11,PTPN23,RAB11FIP2,RAB14,RAN,RANGAP1,RBM22,RER1,RHBDD3,RNF31,RUFY3,SAR1A,SFN,SIX4,SLC25A5,SLC7A11,SUPT6H,TCF7L2,TFDP2,TRAF2,UBE2D3,UFL1,VAMP7,VPS35,VPS4A,WAPL,XPO4 |
| GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION | 0.0e+00 | 2.0e-07 | 1930 | 46 | 13 | CGAS,CHEK1,HELB,PPP4C,PPP4R2,RAD51,RAD51AP1,RIF1,RPA2,SHLD1,SHLD2,TERF2IP,UBQLN4 |
| GO_HISTONE_MRNA_METABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1930 | 25 | 10 | ATM,CPSF2,DCP2,EXOSC10,EXOSC4,LSM11,MTPAP,SLBP,SNRPB,TENT4A |
| GO_IMMUNE_EFFECTOR_PROCESS | 0.0e+00 | 3.0e-07 | 1930 | 1267 | 91 | ACTR3,AP1G1,BTK,C12orf4,CD226,CD3G,CFHR2,CGAS,CLCF1,CRCP,DDX1,DDX60,DENND1B,DOCK2,DPP7,DYNC1LI1,EXOSC3,EXOSC4,EXOSC5,FER,GDI2,GLA,GPATCH3,HSPA6,HSPA8,IGHV3-43,IGKV1D-33,IL18RAP,ILF3,ILRUN,IRAK3,ITCH,ITFG2,KCMF1,KPNB1,LCP1,LYN,LYZ,MICB,NAPRT,NCKAP1,NFKB1,NFKBID,NPLOC4,NSD2,NT5C3A,PAK1,PCBP2,PML,POLR3C,POLR3E,POLR3F,PQBP1,PSMA2,PSMB7,PSMC2,PSMC3,PSMD1,PSMD12,PSMD2,PSMD6,PUM1,PUM2,RAB14,RAB18,RAP2C,RC3H1,RIF1,RIOK3,SHLD1,SHLD2,SLC11A1,SPINK5,STK10,SUCNR1,SUPT6H,THOC1,TICAM1,TRAF2,TRIM56,TSC1,TSTA3,TUBB,UFD1,UNG,VAMP7,VAPA,VAV2,WASF2,YES1,ZC3HAV1 |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 2.0e-07 | 1930 | 1061 | 80 | ABCA1,APTX,ARL6IP1,ATF4,CA3,CAPN2,CASP3,CCNA2,CCNB1,CDK1,CDK2,CHMP5,CLDN4,CREB1,CTPS1,DAXX,DDX11,DNM2,DVL3,EDN1,EEF1B2,FMR1,GABRG3,GNB1,GNRH1,GSK3A,HMGB2,HNRNPA1,HSF1,IL18RAP,KAT7,KDM6B,KLF4,KMT2A,KPNA4,LYN,MCM7,NFE2L2,NFKB1,NOTCH1,NSG1,NUDT15,OR56A4,PAWR,PDCD10,PEA15,PPIF,PPP2CB,PTPN11,RAD51,RAD54L,RBM22,SETDB1,SIRT1,SLC11A1,SLC19A2,SLC22A13,SLC25A19,SLC25A25,SLC25A26,SLC25A32,SLC25A38,SLC25A5,SLC38A9,SLC52A2,SLC66A1,SLC6A9,SLC7A11,SOD1,SORD,SRP72,SYT1,TENT4A,TRAF2,UBE3A,UFL1,UQCRC2,USP47,VPS35,YAP1 |
| GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE | 0.0e+00 | 3.0e-07 | 1930 | 39 | 12 | CUL4A,DDB1,DNAJA1,DTL,MRPS35,RAD18,RFC1,RPA2,UBB,UBC,USP1,WDR48 |
| GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION | 0.0e+00 | 3.0e-07 | 1930 | 64 | 15 | CDCA5,CDT1,CUL3,EDN1,ESPL1,HNRNPU,NSFL1C,NSMCE2,NUP62,NUSAP1,PHB2,PHIP,SH2B1,SLF1,UBE2C |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 3.0e-07 | 1930 | 1716 | 114 | ATF2,ATM,ATXN1L,BAP1,BID,BRCA2,BTK,C18orf54,CASP3,CCNA2,CCNB1,CD274,CDC6,CDK1,CDK2,CHERP,CIP2A,CLCF1,CNOT6,CNOT6L,CREB1,CTBP2,CUL3,CUL4A,DERL2,DMRTA2,DNAJA2,DOT1L,E2F3,EDN1,EEF1E1,EIF5A,FBXO2,FER,FGFR1OP,FOXJ2,FRZB,GGNBP2,GID8,GNRH1,HGS,HIPK1,HMGB2,HNRNPU,HP1BP3,HSF1,IQGAP3,JTB,KLB,KLF4,LYN,MAFG,MARCHF7,MDM4,MECP2,MED1,MED31,MFN2,MTA3,MTBP,N4BP2L2,NAP1L1,NOTCH1,NUP62,PAK1,PAWR,PDCD10,PDCL3,PGGT1B,PHB2,PHIP,PML,PRC1,RBBP4,RBM10,RC3H1,RICTOR,RNASEH2B,RNF10,RNF126,SF1,SFN,SHCBP1,SINHCAF,SIRT1,SIX4,SLC25A33,SLC25A5,SLC7A11,SMAD4,SOX15,SPDYA,SSR1,STRN,SYF2,TBRG1,TBX3,TCF7L2,THAP12,TIAL1,TICAM1,TMEM119,TSC1,UBE2A,UFL1,WAPL,WDR48,XIAP,YAP1,YES1,ZBTB49,ZEB1,ZNF16,ZNF335 |
| GO_MACROAUTOPHAGY | 0.0e+00 | 3.0e-07 | 1930 | 295 | 34 | ATG12,ATP6V0A2,ATP6V1G1,ATP6V1H,BAG3,CASP3,CHMP4B,CSNK2A2,GABARAPL1,HGS,ILRUN,LGALS8,MAPK8,MFN2,NSFL1C,PLAA,PRKAB1,RAB1A,RAB3GAP1,SIRT1,SLC38A9,SMURF1,SNX5,STAM,TSC1,UBQLN4,USP30,UVRAG,VDAC1,VPS26A,VPS35,VPS37A,VPS4A,WAC |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 3.0e-07 | 1930 | 542 | 50 | ABL2,ADIPOR1,AIDA,ARRDC3,ATM,BANK1,BCL2L12,BCL2L2,BID,C3orf33,CDK5RAP3,CRTC3,CUL3,DNAJA1,DYRK2,FBXW11,GPATCH3,GSK3A,IRAK3,ITCH,ITFG2,KLF4,LEMD2,LYN,MARCHF7,MBIP,MFN2,NCOR1,NDUFS3,NFE2L2,NFKBID,NONO,NPLOC4,NUP62,OTUD7B,PPIF,PPM1A,PPP2CB,RASA2,RIOK3,SCAI,SIRT1,SMAD4,TAF9B,TSC1,UFD1,USP47,VDAC2,YJU2,ZNF675 |
| GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | 0.0e+00 | 4.0e-07 | 1930 | 84 | 17 | CCNT1,DHX34,FMR1,HNRNPK,HNRNPL,HNRNPU,PABPC1,PAIP1,RBM10,RBM42,RBMX,RNF40,RNPS1,SLC11A1,SRSF4,TENT4A,ZC3H14 |
| GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 4.0e-07 | 1930 | 227 | 29 | AKAP8L,ANP32B,BAG3,BAG4,BAP1,CSNK2A2,CTDSPL2,DERL2,GSK3A,LCP1,NDEL1,NUP62,PAK1,PCM1,PDCD10,PPM1A,PTPN11,RAN,RANGAP1,RBM22,RNF31,RUFY3,SAR1A,SFN,SUPT6H,TCF7L2,UBE2D3,VAMP7,XPO4 |
| GO_FEMALE_SEX_DIFFERENTIATION | 0.0e+00 | 4.0e-07 | 1930 | 116 | 20 | AFP,ATM,BRCA2,CASP3,DMC1,EIF2B4,FANCG,FOXC1,GNRH1,KMT2B,LHFPL2,MSH4,SIRT1,SMAD4,SOD1,TBX3,TYRO3,UBB,UBE3A,ZFP42 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 4.0e-07 | 1930 | 326 | 36 | ABHD17B,ANP32B,AP2B1,BAG3,BAP1,BID,CDK1,CDK5RAP3,CDT1,CENPQ,CSNK2A2,CTDSPL2,DKC1,DPP10,GSK3A,KAT7,MAPK8,NUP62,PAK1,PCM1,PDCD10,PPM1A,PPP3CC,PPP3R1,RAB11FIP2,RAN,RBM22,RER1,RNF31,RUFY3,SAR1A,SFN,TCF7L2,TFDP2,UBE2D3,XPO4 |
| GO_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 4.0e-07 | 1930 | 326 | 36 | AXIN1,CAMSAP1,CHMP5,CKAP2,CKAP5,CLASP2,DVL3,EIF5A,GABARAPL1,GRWD1,GSPT1,HDGFL3,HSPA8,IRAK3,KIF18A,KIF2C,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTPN,MTRF1L,OGFOD1,PEX14,SCAF4,SCAF8,SET,TFIP11,TWF1,UBQLN4,UVRAG,VPS4A |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1930 | 371 | 39 | AXIN1,CSNK1G1,CUL3,DVL3,FRZB,GID8,GSK3A,HIC1,NFKB1,NOTCH1,PFDN5,PPM1A,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,TCF7L2,TNKS,USP47,VPS35,XIAP,YAP1,ZEB2,ZNRF3 |
| GO_CENTRIOLE_ASSEMBLY | 0.0e+00 | 4.0e-07 | 1930 | 40 | 12 | C2CD3,CDK2,CEP120,CEP135,CEP72,CEP76,CNTROB,KIAA0753,MCIDAS,NUP62,PLK4,WDR62 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 4.0e-07 | 1930 | 243 | 30 | ABCA1,ACTR3,ATM,BAG4,BAIAP2L1,BID,BIN1,CDT1,CREB1,CUL4A,DDB1,DRG1,FAF1,FER,GTF2H2,LCP1,MECP2,NCKAP1,PAK1,PSMC2,PSMC3,PSMC4,PSMC6,RICTOR,RPA2,SLAIN2,SLF1,WASH3P,WASH6P,WASHC1 |
| GO_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 4.0e-07 | 1930 | 435 | 43 | ADIPOR1,AZIN1,CLTC,DDB1,DYRK2,FOXK2,GSK3A,KPNB1,NFKB1,NFYC,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OAZ3,PFKFB3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAE1,RAN,SIK1,SIRT1,SLC7A11,SOD1 |
| GO_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1930 | 129 | 21 | AXIN1,CNOT2,CNOT9,DAXX,DDX54,DNAJA1,EGLN2,KAT5,MED1,NCOR1,PAK1,PHB2,RAN,RNF4,RNF6,SIRT1,STRN3,UBE2I,UBE3A,UFL1,YAP1 |
| GO_RESPONSE_TO_LIPID | 0.0e+00 | 4.0e-07 | 1930 | 930 | 72 | ABCA1,ABL2,ADNP2,AKAP8,ATM,AXIN1,BCL2L2,CACTIN,CAPN2,CASP3,CCNA2,CCNB1,CD274,CHMP5,CLDN4,CNOT2,CNOT9,CREB1,DAXX,DDX54,DNAJA1,EDN1,EGLN2,ELK1,FER,GDAP2,GNB1,GNRH1,GPR83,HMGB2,HNRNPU,HSF1,IRAK3,KAT5,KIF18A,KLF4,LANCL2,LYN,MAPK8,MBD4,MED1,MICB,NCOR1,NFKB1,NFKBIB,NOTCH1,NR2C2,PABPN1,PAF1,PAK1,PHB2,PLAA,RAN,RBBP8,RNF4,RNF6,SIRT1,SLC11A1,SNW1,STRN3,TAB2,THBD,TICAM1,TNIP2,UBE2I,UBE3A,UCP3,UFL1,WNT9B,YAP1,YES1,YY1 |
| GO_TRNA_MODIFICATION | 0.0e+00 | 5.0e-07 | 1930 | 86 | 17 | ADAT2,ALKBH1,ALKBH8,CDKAL1,DUS3L,HSD17B10,NSUN3,PUS1,PUS7,SEPHS1,THUMPD1,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,WDR4 |
| GO_CYTOKINE_PRODUCTION | 0.0e+00 | 5.0e-07 | 1930 | 808 | 65 | ABCA1,AKAP8,ARFGEF2,ATF2,ATF4,AZI2,BANK1,BAP1,BTK,CACTIN,CAPN2,CD200R1,CD226,CD274,CGAS,CLEC4A,CRCP,CREB1,CREBBP,DDX1,DDX60,DENND1B,GPATCH3,HMGB2,HSF1,IL18RAP,ILRUN,IRAK3,ITCH,KAT5,KLF4,LRRFIP1,LYN,NFKB1,NMI,NOTCH1,NPLOC4,OTUD7B,PAWR,PCBP2,PML,POLR3C,POLR3E,POLR3F,PQBP1,PTPN11,PUM1,PUM2,RAB1A,REL,RIOK3,RPS6KA5,SIRT1,SLC11A1,SMAD4,SOD1,STOML2,SUCNR1,TAX1BP1,TICAM1,TRAF2,TRAIP,TRIM56,UFD1,YY1 |
| GO_NUCLEUS_ORGANIZATION | 0.0e+00 | 5.0e-07 | 1930 | 130 | 21 | AKAP8L,ANKLE2,BIN1,CCNB1,CCNB2,CDK1,CHMP4B,CHMP5,HMGB2,LEMD2,NDEL1,NSFL1C,NUP153,NUP205,PES1,PML,SF1,SRPK1,TMEM170A,USPL1,VPS4A |
| GO_REGULATION_OF_SPINDLE_ORGANIZATION | 0.0e+00 | 5.0e-07 | 1930 | 41 | 12 | CHMP4B,CHMP5,CLTC,DRG1,HNRNPU,NUP62,RAE1,RNF4,SENP6,STAG1,STAG2,TPX2 |
| GO_ATP_METABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 1930 | 303 | 34 | ATP5F1B,ATP5MG,ATP5PB,BID,CCNB1,CDK1,COA6,COX5A,CYC1,FOXK2,HKDC1,HSPA8,MECP2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PFKFB3,PPIF,RAE1,SLC25A25,SLC25A33,SLC4A1,STOML2,UQCRC2,UQCRH |
| GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 6.0e-07 | 1930 | 108 | 19 | ACD,ATM,AURKB,CHTF18,DCP2,DKC1,DNAJC2,EXOSC10,HNRNPA1,HNRNPU,KLF4,MAP2K7,NAF1,NEK2,NEK7,SH2B1,SMG5,SMG7,TNKS |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 0.0e+00 | 6.0e-07 | 1930 | 131 | 21 | ATM,CCNB1,CDC25C,CDK1,CDK2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,FBXO7,KLF4,MDM4,PML,RFWD3,RPA2,SFN,TFDP2,WEE1 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY | 0.0e+00 | 6.0e-07 | 1930 | 120 | 20 | CASC3,DCP1A,DCP2,DHX34,EIF3E,EXOSC10,GSPT1,MAGOHB,PABPC1,RBM8A,RNPS1,RPL21,RPL22,RPS7,SMG1,SMG5,SMG7,SMG8,SMG9,UPF3B |
| GO_CILIUM_ORGANIZATION | 0.0e+00 | 7.0e-07 | 1930 | 381 | 39 | ACTR3,ATMIN,C2CD3,CCDC13,CDK1,CDKL1,CEP120,CEP135,CEP57,CEP72,CEP76,CEP89,CFAP157,CKAP5,CNTROB,DNM2,FBF1,FGFR1OP,FOPNL,HAUS1,HAUS2,HAUS4,HAUS5,HAUS6,HAUS7,IQCB1,MCIDAS,MNS1,NEK2,NOTCH1,ODF2,PCM1,PLK4,PTPN23,RO60,RSPH4A,TCHP,TTC26,TUBB |
| GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | 0.0e+00 | 7.0e-07 | 1930 | 78 | 16 | AGO2,CCNB1,CNOT6L,CPEB1,DAZAP1,HSF1,NUDT21,PABPC1,PAF1,PUM1,RBMX,RC3H1,SNW1,YTHDF2,YTHDF3,ZC3HAV1 |
| GO_ATP_DEPENDENT_CHROMATIN_REMODELING | 0.0e+00 | 8.0e-07 | 1930 | 89 | 17 | ACTL6A,ACTR6,ACTR8,ANP32E,CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,H4-16,HJURP,MIS18A,RBBP4,SPTY2D1 |
| GO_REGULATION_OF_TRANSLATIONAL_INITIATION | 0.0e+00 | 8.0e-07 | 1930 | 79 | 16 | AGO2,ALKBH1,ATF4,BANK1,DDX1,EIF3E,EIF3H,EIF4B,EIF4G2,EIF5,FMR1,MTIF2,PAIP1,PPP1R15A,YTHDF2,YTHDF3 |
| GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION | 0.0e+00 | 8.0e-07 | 1930 | 35 | 11 | CPSF2,CPSF7,FIP1L1,LSM11,NUDT21,PABPN1,PAPOLA,SCAF4,SCAF8,SLBP,SNRPB |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | 1.0e-07 | 9.0e-07 | 1930 | 266 | 31 | BAG3,CDK1,CDK5RAP3,DKC1,DNAJB6,FAM53C,HNRNPU,ILRUN,IPO11,IPO7,KAT7,KPNA2,KPNA4,KPNB1,MED1,NUP153,NUP50,NUP62,NXT1,OTUD7B,PAF1,PHB2,PML,RAN,RANGAP1,RBM22,RGPD6,SIX4,SUPT7L,TBRG1,TNPO2 |
| GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION | 1.0e-07 | 1.0e-06 | 1930 | 135 | 21 | ATF2,ATP5F1B,ATP5MG,ATP5PB,BID,BLOC1S2,CHCHD3,GSK3A,MAIP1,MAPK8,MFN2,PPIF,PPP3CC,PPP3R1,SAMM50,SFN,SLC25A5,TFDP2,TIMM10,TIMM50,TMEM11 |
| GO_PROTEIN_AUTOUBIQUITINATION | 1.0e-07 | 1.0e-06 | 1930 | 70 | 15 | CNOT4,ERCC8,ITCH,MARCHF7,OBI1,RAD18,RNF10,RNF19B,RNF4,TRAF2,UBE2A,UBE2D3,UBE2T,UBE3A,UHRF2 |
| GO_PROTEASOMAL_UBIQUITIN_INDEPENDENT_PROTEIN_CATABOLIC_PROCESS | 1.0e-07 | 1.0e-06 | 1930 | 22 | 9 | NFE2L2,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7 |
| GO_REGULATION_OF_SISTER_CHROMATID_COHESION | 1.0e-07 | 1.0e-06 | 1930 | 22 | 9 | BUB1,CDCA5,DDX11,ESPL1,NSMCE2,RAD21,SLF1,TNKS,WAPL |
| GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS | 1.0e-07 | 1.1e-06 | 1930 | 148 | 22 | AGO2,CNOT2,CNOT6,CNOT6L,CPSF2,CPSF6,CPSF7,DCP2,DIS3,EXOG,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,FIP1L1,NOL9,NUDT21,POP7,REXO2,RNASEH2A,RNASEH2B |
| GO_DEVELOPMENT_OF_PRIMARY_FEMALE_SEXUAL_CHARACTERISTICS | 1.0e-07 | 1.2e-06 | 1930 | 102 | 18 | AFP,ATM,BRCA2,CASP3,DMC1,EIF2B4,FANCG,FOXC1,GNRH1,KMT2B,LHFPL2,MSH4,SIRT1,SMAD4,SOD1,UBB,UBE3A,ZFP42 |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 1.0e-07 | 1.2e-06 | 1930 | 704 | 58 | ADIPOR1,AKAP8,AKR1C1,ATP6V0A2,ATP6V1G1,ATP6V1H,AXIN1,BAIAP2L1,BCL2L2,CAPN10,CCNA2,CDC6,CNOT2,CNOT9,CPEB1,CREB1,CTSL,DAXX,DDX54,DNAJA1,EDN1,EGLN2,ELK1,FER,GNB1,GSK3A,HNRNPU,HSF1,KAT5,KIF18A,LANCL2,LYN,MED1,NCOR1,NDEL1,NFE2L2,NFKB1,NOTCH1,NR2C2,NUCKS1,NUP62,PAK1,PHB2,PHIP,PTPN11,RAN,RANGAP1,RNF4,RNF6,SIRT1,SLC25A33,STRN3,TSC1,UBE2I,UBE3A,UCP3,UFL1,YAP1 |
| GO_PROTEIN_SUMOYLATION | 1.0e-07 | 1.2e-06 | 1930 | 81 | 16 | NSMCE2,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,RAE1,RANGAP1,SENP1,SENP5,SENP6,SUMO2,SUMO3,UBA2,UBE2I |
| GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | 1.0e-07 | 1.2e-06 | 1930 | 328 | 35 | AIPL1,ATF4,ATM,AURKB,BAG3,CASP3,CDC25A,CHEK1,CREBBP,DDB1,DNM2,ELK1,FMR1,GNB1,GRK7,HSF1,INTS7,MAPK8,MBIP,MTPN,NFKB1,NUCKS1,POLK,PTPN11,RAD1,RAD51,RAD51AP1,RRH,SDE2,SIRT1,TLK2,TNFRSF10A,USP47,YAP1,YY1 |
| GO_REGULATION_OF_AUTOPHAGY | 1.0e-07 | 1.2e-06 | 1930 | 328 | 35 | ABL2,ATM,ATP6V0A2,ATP6V1G1,ATP6V1H,BAG3,CASP3,CHMP4B,CISD2,CSNK2A2,EIF4G2,FBXO7,FOXK2,GSK3A,KAT5,MAPK8,MFN2,PRKAB1,RAB3GAP1,SIRT1,SLC38A9,SMURF1,SNX5,TAB2,TICAM1,TLK2,TSC1,UBQLN4,USP30,UVRAG,VDAC1,VPS26A,VPS35,WAC,WASHC1 |
| GO_MULTI_ORGANISM_LOCALIZATION | 1.0e-07 | 1.3e-06 | 1930 | 62 | 14 | FMR1,KPNA2,KPNB1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,RAE1,RAN,UBB,UBC,VPS37A |
| GO_REGULATION_OF_CHROMOSOME_SEPARATION | 1.0e-07 | 1.3e-06 | 1930 | 62 | 14 | ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDT1,CSNK2A2,CUL3,DYNC1LI1,ESPL1,NSMCE2,PSMG2,RAD21 |
| GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 1.0e-07 | 1.4e-06 | 1930 | 537 | 48 | ACTR3,AP3B1,ATM,BLOC1S2,CCNB1,CDCA5,CDT1,CENPA,CENPQ,CHERP,CHMP4B,CHMP5,CLASP2,CNIH1,CUL3,DNM2,ESPL1,GOSR1,HNRNPU,IBTK,ITPR3,KIF18A,KIF2C,KLHL21,KPNB1,LYN,MCPH1,MIS12,NDEL1,NSFL1C,NUF2,NUP62,NUSAP1,PARD3,PDCD10,PEF1,PML,PPP6R1,RAB11FIP2,RAB1A,SAR1A,SEC24B,SEC24C,SMURF1,TMED2,TRAPPC10,VAMP7,VPS4A |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 1.0e-07 | 1.6e-06 | 1930 | 362 | 37 | ADRM1,ANP32B,ATXN3,AXIN1,BAG2,BID,CASP10,CLDN4,CLN6,COA8,COP1,DDA1,FBXW11,FMR1,GSK3A,HSF1,KHDC1L,LYN,MTCH1,NFE2L2,PML,PSMC1,PSMC2,PSMC4,PSME2,RCHY1,RNF19B,RNF40,SART3,SENP1,SIRT1,SMURF1,SUMO2,TNFRSF10A,TRAF2,WDR48,ZFAND2A |
| GO_SISTER_CHROMATID_COHESION | 1.0e-07 | 1.6e-06 | 1930 | 63 | 14 | BUB1,CDCA5,DDX11,ESPL1,NSMCE2,PHB2,RAD21,SLF1,SMC1B,STAG1,STAG2,TENT4A,TNKS,WAPL |
| GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS_VIA_GERMLINE_RECOMBINATION_WITHIN_A_SINGLE_LOCUS | 1.0e-07 | 1.6e-06 | 1930 | 63 | 14 | ATM,CLCF1,DCAF1,EXOSC3,HMGB2,NSD2,RIF1,SHLD1,SHLD2,SUPT6H,TCF3,THOC1,UNG,XRCC4 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 1.0e-07 | 1.7e-06 | 1930 | 625 | 53 | AP2B1,ARL6IP1,BAG4,BID,BLZF1,CHMP4B,CLASP2,CLTC,DPP10,GET3,GORASP2,GPR158,HGS,LIN7C,LZTFL1,MAIP1,MAPK8,NSG1,PAK1,PARD3,PPP3CC,PPP3R1,RAB11FIP2,RAB15,RAB38,RAB3GAP1,RABGEF1,RER1,RPL21,RPL22,RPS7,SAMM50,SEC61A2,SEC62,SEC63,SFN,SLC4A1,SLC7A11,SLMAP,SMURF1,SRP72,SSR1,SSR2,SSR3,TFDP2,TIMM10,TMED2,TTC7B,VAMP7,VPS35,VPS37A,VPS4A,ZDHHC18 |
| GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR | 1.0e-07 | 1.7e-06 | 1930 | 73 | 15 | COPS2,COPS3,COPS7B,CUL4A,DDB1,ERCC8,GTF2H2,ISY1,POLK,RFC1,RPA2,UBB,UBC,USP7,XAB2 |
| GO_NEGATIVE_REGULATION_OF_MRNA_PROCESSING | 1.0e-07 | 1.8e-06 | 1930 | 30 | 10 | CCNT1,HNRNPK,HNRNPL,RBM10,RBM42,RBMX,RNF40,RNPS1,SRSF4,ZC3H14 |
| GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 1.0e-07 | 1.8e-06 | 1930 | 105 | 18 | AKAP8L,ANP32B,BAG3,CPSF6,CTDSPL2,NUP153,NUP62,PPM1A,PTPN11,RAN,RANGAP1,RBM22,RBM26,RBM27,SFN,SUPT6H,TCF7L2,XPO4 |
| GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 1.0e-07 | 1.8e-06 | 1930 | 232 | 28 | APTX,BTK,CAPN2,CASP3,CCNA2,CDK1,CDK2,COA8,DNM2,EDN1,FER,HSF1,IL18RAP,KDM6B,KLF4,KPNA4,MAPK8,NFE2L2,NUDT15,PAWR,PDCD10,PPIF,PPP2CB,SIRT1,SOD1,TRAF2,UBE3A,UCP3 |
| GO_DNA_MODIFICATION | 1.0e-07 | 2.0e-06 | 1930 | 117 | 19 | ALKBH1,ALKBH3,ASCC2,BAZ2A,CDADC1,EXOSC3,EXOSC4,EXOSC5,GSK3A,KMT2A,MBD4,MECP2,METTL4,MIS18A,OTUD4,PARP2,TET3,UNG,USP7 |
| GO_PROTEIN_IMPORT | 1.0e-07 | 2.0e-06 | 1930 | 192 | 25 | BAG3,FAM53C,GRPEL1,GRPEL2,HSPA8,IPO11,IPO7,KPNA2,KPNA4,KPNB1,MED1,NUP153,NUP50,NUP62,NXT1,PEX14,PHB2,PML,RAN,RBM22,RGPD6,SAMM50,TIMM44,TIMM50,TNPO2 |
| GO_CELLULAR_KETONE_METABOLIC_PROCESS | 1.0e-07 | 2.2e-06 | 1930 | 248 | 29 | ADIPOR1,AFP,AKR1C1,AZIN1,CBR3,COQ8A,NDUFA9,OAZ3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SIRT1,SLC7A11 |
| GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION | 1.0e-07 | 2.1e-06 | 1930 | 55 | 13 | CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,H4-16,HAT1,HJURP,MIS18A,RBBP4 |
| GO_MEIOSIS_I_CELL_CYCLE_PROCESS | 1.0e-07 | 2.2e-06 | 1930 | 118 | 19 | ATM,BRCA2,CCNB1IP1,CDC25A,CDC25C,DMC1,ESPL1,FANCM,KLHDC3,MCMDC2,MND1,MSH4,MUS81,PSMC3IP,RAD21,RAD51,RAD54L,TOP2A,UBB |
| GO_CYTOPLASMIC_TRANSLATIONAL_INITIATION | 2.0e-07 | 2.5e-06 | 1930 | 31 | 10 | DENR,EIF2S3B,EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF4A1,EIF5,YTHDF2 |
| GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | 2.0e-07 | 2.5e-06 | 1930 | 181 | 24 | ADIPOR1,AZIN1,OAZ3,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,SIRT1,SLC7A11 |
| GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS | 2.0e-07 | 2.5e-06 | 1930 | 75 | 15 | ATM,CLCF1,DCAF1,EXOSC3,HMGB2,NSD2,POLL,RIF1,SHLD1,SHLD2,SUPT6H,TCF3,THOC1,UNG,XRCC4 |
| GO_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE | 2.0e-07 | 2.6e-06 | 1930 | 56 | 13 | ATM,AURKB,BUB1,CCNB1,CDC27,CDC6,CDT1,CUL3,DYNC1LI1,ESPL1,NSMCE2,PSMG2,RAD21 |
| GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 2.0e-07 | 2.5e-06 | 1930 | 47 | 12 | CACTIN,GPATCH3,ILRUN,ITCH,NMI,NPLOC4,PCBP2,REL,TAX1BP1,TRAIP,UFD1,YY1 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 2.0e-07 | 2.5e-06 | 1930 | 1163 | 82 | AGO2,AP2B1,ATF2,CAMSAP1,CAPN2,CLASP2,CLDN4,CLTC,DNM2,DVL3,EDN1,ERAP1,FGD1,FMNL3,FOXC1,FOXJ2,GNA13,HGS,HIPK1,HOXA11,HOXC11,IFRD1,ITSN2,KLF4,MECP2,MED1,MYO19,NDEL1,NFE2L2,NOTCH1,PAK1,PDCD10,PDCL3,PHB2,PHIP,PLAA,PML,PQBP1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,QRICH1,RAB21,RC3H1,RCC2,RND3,RNF6,RUFY3,SEC24B,SH3KBP1,SIRT1,SIX4,SMAD4,SMURF1,SPART,SPINK5,SRPX2,STRIP1,SYT1,TBR1,UBE3A,VAMP7,VPS35,WNT9B,ZEB2,ZNRF3 |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 2.0e-07 | 2.8e-06 | 1930 | 1071 | 77 | ANKRD11,AP2B1,AQP6,ATF2,C12orf57,C2CD3,CLTC,COL6A3,CUL1,CUL3,DVL3,EDN1,FEM1B,FGD1,FOXC1,FRZB,GSK3A,HIPK1,HOXA11,HOXC11,HOXC9,KDM6A,LAMA2,LAMB4,LCTL,LEMD2,MATN1,MDM4,MED1,MFN2,MTHFD1,MYLK2,NAB1,NOTCH1,NRL,NSD2,PHB2,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RBM15,RELT,SEC24B,SIX4,SMAD4,SMURF1,SOD1,SP3,TBR1,TBX3,TMED2,TMEM119,WDR48,WNT9B,YAP1,YY1,ZEB1,ZFAND5,ZNF335,ZNRF3 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 2.0e-07 | 2.7e-06 | 1930 | 995 | 73 | ACTL6A,ANKLE2,ANP32B,ARCN1,ARHGAP11B,ATM,ATP5PB,ATXN1L,BAG3,BCAN,BIN1,BRCA2,C12orf57,C2CD3,CASP3,CDK5RAP3,CEP120,CLCF1,CREB1,CSNK2A2,DMRTA2,DNAJB1,DRP2,EIF2B4,EZH1,FOXC1,GLUD1,ISL2,KDM6B,LYN,MCPH1,MECP2,MED1,MTPN,NCKAP1,NDEL1,NDUFS3,NHLH1,NOTCH1,NOTCH2NLA,PAK1,PBX3,PCM1,PPP3CC,PTPN11,PTS,RAB18,RAB3GAP1,RAD1,RRM1,SEC24B,SLC7A11,SMG9,SNRPB,SPINK5,SYT1,TBR1,TBX3,TMEM108,TSC1,TYRO3,UBA6,UBB,UBE3A,WDR62,WNT9B,XAB2,ZEB1,ZEB2,ZIC5,ZNF148,ZNF335,ZNF430 |
| GO_OXIDATIVE_PHOSPHORYLATION | 2.0e-07 | 2.8e-06 | 1930 | 144 | 21 | ATP5F1B,ATP5MG,ATP5PB,BID,CCNB1,CDK1,COA6,COX5A,CYC1,MECP2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,PPIF,SLC25A33,STOML2,UQCRC2,UQCRH |
| GO_NEGATIVE_REGULATION_OF_NEURON_DEATH | 2.0e-07 | 3.0e-06 | 1930 | 210 | 26 | ALKBH1,AP2B1,ATF4,BTBD10,CD200R1,CHMP4B,CLCF1,CREB1,FBXO7,GFRAL,HSF1,MECP2,NONO,OXR1,PARP2,PSMC1,REL,SET,SIRT1,SIX4,SLC7A11,SOD1,TRAF2,TSC1,TYRO3,VPS35 |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 2.0e-07 | 3.0e-06 | 1930 | 518 | 46 | AIDA,CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK1,CDK12,CDK5RAP3,CHORDC1,DAXX,DNAJA1,DVL3,EDN1,FBXO7,GFRAL,HGS,IPO7,IQGAP3,IRAK3,LYN,MAP2K7,MBIP,NUP62,PAK1,PDCD10,PEA15,PTPN11,SFN,SIRT1,SOD1,SPDYA,TAB2,TELO2,TRAF2,UBB,UBC,UVRAG,ZEB2,ZNF675 |
| GO_CHROMATIN_REMODELING_AT_CENTROMERE | 2.0e-07 | 3.2e-06 | 1930 | 48 | 12 | CENPA,CENPK,CENPM,CENPO,CENPP,CENPQ,CENPT,CENPW,H4-16,HJURP,MIS18A,RBBP4 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 2.0e-07 | 3.2e-06 | 1930 | 587 | 50 | AIDA,ANKLE2,BAG4,C3orf33,CACTIN,CASP3,CCNB1,CD2BP2,CDK5RAP3,CHORDC1,DBNDD2,DNAJA1,ELL,FBXO7,FGFR1OP,GGNBP2,GSK3A,HNRNPU,IBTK,IPO7,IRAK3,ITCH,KLF4,LEMD2,LYN,MASTL,MBIP,NCOR1,NUP62,PAK2,PARD3,PARP14,PCDH11X,PPIF,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R5D,PRKRIP1,PWP1,RBM26,SET,SFN,SIRT1,SMAD4,TERF2IP,WASHC1,ZNF675 |
| GO_CHAPERONE_COFACTOR_DEPENDENT_PROTEIN_REFOLDING | 2.0e-07 | 3.3e-06 | 1930 | 32 | 10 | BAG1,DNAJB1,DNAJB14,DNAJC7,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,ST13 |
| GO_POSITIVE_REGULATION_OF_CELL_GROWTH | 2.0e-07 | 3.3e-06 | 1930 | 171 | 23 | ADNP2,CDKN2AIP,DERL2,EDN1,EIF4G2,EXOSC4,EXOSC9,FGFR1OP,ITSN2,MTPN,NDEL1,PAK1,PARP2,PLAA,RUFY3,SFN,SLC25A33,SMURF1,SUPV3L1,SYT1,TAF9B,USP47,ZNF639 |
| GO_REGULATION_OF_CELL_CYCLE_CHECKPOINT | 2.0e-07 | 3.3e-06 | 1930 | 32 | 10 | CCNB1,CDT1,CUL4A,DYNC1LI1,FEM1B,RFWD3,RNASEH2B,RPA2,THOC1,THOC5 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 2.0e-07 | 3.5e-06 | 1930 | 1825 | 115 | AAMP,ABCA1,ABL2,ADIPOR1,AGO2,AP3B1,ARFGEF2,ATF1,ATF2,ATF4,ATP5F1B,ATXN1L,BIN1,BTK,CAPN7,CCNB1,CD226,CD274,CDK1,CGAS,CLASP2,CLCF1,CNOT3,CRCP,CREB1,CREBBP,DDX1,DDX60,DMRTA2,DVL3,EDN1,ERAP1,EXOSC3,FMR1,FOXC1,GPATCH3,GSK3A,HIPK1,HMGB2,HOXA11,HOXC11,HSF1,IQGAP3,IRAK3,ITSN2,KDM6B,KLF4,LRRFIP1,LRRTM2,LYN,MAP4K4,MAPK6,MED1,MFN2,MTPN,N4BP2L2,NAP1L1,NDEL1,NFE2L2,NFKB1,NFKBID,NKAP,NOTCH1,NPLOC4,NR2C2,NSD2,NUDT21,PAK1,PARD3,PARP2,PDCL3,PLAA,POLR3C,POLR3E,POLR3F,PQBP1,PRKAB1,PTPN11,PUM1,PUM2,RAB21,RIF1,RIOK3,RNF10,RUFY3,SART1,SF3A2,SHLD1,SHLD2,SIRT1,SIX4,SLC11A1,SMAD4,SMURF1,SNW1,SNX5,SOD1,SRPX2,SRRT,SYT1,TCF3,TCF7L2,THBD,TICAM1,TMEM119,TRAF2,TWF1,UFD1,UFL1,VAMP7,YAP1,ZEB1,ZEB2,ZNF16,ZNF335 |
| GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | 2.0e-07 | 3.5e-06 | 1930 | 313 | 33 | BAG4,CACTIN,CASP3,EDN1,HIPK1,MAP2K7,NFE2L2,NFKB1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RNF31,SIRT1,TAX1BP1,TRAF2,TRAIP,ZNF675 |
| GO_CYTOSOLIC_TRANSPORT | 2.0e-07 | 3.7e-06 | 1930 | 159 | 22 | AP1G1,CLTC,DENND5A,GOSR1,MTMR2,PTPN23,RAB14,RAB21,RBSN,RNF126,SNX16,SNX5,STX16,TMEM87A,TRAPPC10,VPS26A,VPS35,VPS51,VTI1A,WASH3P,WASH6P,WASHC1 |
| GO_ERAD_PATHWAY | 2.0e-07 | 3.7e-06 | 1930 | 99 | 17 | ATXN3,AUP1,DERL2,DNAJB14,ECPAS,FBXO2,FBXO6,HSP90B2P,NFE2L2,NPLOC4,POMT2,PSMC6,TMUB2,UBXN4,UBXN8,UFD1,USP14 |
| GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI | 2.0e-07 | 3.7e-06 | 1930 | 88 | 16 | CLTC,DENND5A,GOSR1,RBSN,RNF126,SNX5,STX16,TMEM87A,TRAPPC10,VPS26A,VPS35,VPS51,VTI1A,WASH3P,WASH6P,WASHC1 |
| GO_REGULATION_OF_TRANSPORT | 3.0e-07 | 4.3e-06 | 1930 | 1894 | 118 | ABCA1,ABL2,AKAP8L,ANKRD13D,ANP32B,AP1G1,AP2B1,ARL6IP1,ATAD1,ATF4,AZIN1,BAG3,BAG4,BANK1,BAP1,BID,BIN1,C12orf4,CAMK2G,CAPN10,CBLL1,CD200R1,CD274,CLASP2,COA8,CPSF6,CREB1,CSNK2A2,CTDSPL2,DERL2,DNAJA1,DNM2,DOCK2,DPP10,EDN1,FER,FMR1,FXYD5,GALR2,GLUD1,GOSR1,GPR89A,GPR89B,GSK3A,HGS,HNRNPK,HSPA8,ITPR3,KCNK7,KMT2A,LCP1,LRRTM2,LYN,MAPK8,MTMR2,MYLK2,NCOR1,NDEL1,NFE2L2,NFKB1,NOTCH1,NUP153,NUP62,OAZ3,OR56A4,PAK1,PCM1,PDCD10,PEA15,PHB2,PLAA,PML,POFUT2,PPIF,PPM1A,PPP3CC,PPP3R1,PTPN11,PTPN23,RAB15,RAB21,RAB3GAP1,RAN,RANGAP1,RBM22,RBM26,RBM27,REM2,RHBDD3,RNF31,RUFY3,SAR1A,SEC24B,SFN,SIK1,SIRT1,SLC11A1,SLC25A5,SLC30A5,SLC7A11,SLMAP,SMAD4,SNX5,SOD1,STAM,STX18,SUPT6H,SYT1,TCF7L2,TFDP2,TRAF2,UBE2D3,VAMP7,VPS35,VPS4A,XPO4,YES1,YRDC |
| GO_DE_NOVO_PROTEIN_FOLDING | 3.0e-07 | 4.6e-06 | 1930 | 41 | 11 | BAG1,DNAJB1,DNAJB14,DNAJC2,DNAJC7,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,ST13 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 3.0e-07 | 4.7e-06 | 1930 | 973 | 71 | ABCA1,ATF1,ATF4,AXIN1,BCL2L2,CASP3,CASP7,CCNA2,CCNB1,CDK1,CGAS,CLDN4,CNOT2,CNOT9,DAXX,DDX1,DDX54,DNAJA1,DNM2,EDN1,EGLN2,ELK1,ERCC8,GNB1,GNRH1,GPR83,GSK3A,HMGB2,HNRNPU,HSF1,IRAK3,KAT5,KIF18A,KLF4,LYN,MBD4,MED1,NCOR1,NFKB1,NOTCH1,NR2C2,NSG1,OR56A4,PAK1,PAK2,PEA15,PHB2,PQBP1,PSMB2,RAD51,RAE1,RAN,RBBP8,RIOK3,RNF4,RNF6,SIRT1,SLC3A2,SLC7A11,SNW1,SOD1,STRN3,TAF2,THBD,TICAM1,UBE2I,UBE3A,UCP3,UFL1,VPS35,YAP1 |
| GO_RNA_METHYLATION | 3.0e-07 | 4.8e-06 | 1930 | 79 | 15 | ALKBH8,CBLL1,HSD17B10,MRM3,MTERF4,NSUN3,RBM15,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,VIRMA,WDR4,ZCCHC4 |
| GO_MEIOTIC_CHROMOSOME_SEGREGATION | 3.0e-07 | 5.1e-06 | 1930 | 90 | 16 | ACTR3,ATM,BUB1,CCNB1IP1,DMC1,ESPL1,FANCM,MCMDC2,MSH4,MUS81,NCAPH,NCAPH2,NUF2,SMC4,TOP2A,WAPL |
| GO_RESPONSE_TO_HORMONE | 3.0e-07 | 5.1e-06 | 1930 | 994 | 72 | ADIPOR1,AKAP8,AKR1C1,ATP6V0A2,ATP6V1G1,ATP6V1H,AXIN1,BAIAP2L1,BCL2L2,CAPN10,CASP3,CCNA2,CDC6,CLDN4,CNOT2,CNOT9,CPEB1,CREB1,CTSL,CYC1,DAXX,DDX54,DNAJA1,EDN1,EGLN2,EIF2B4,ELK1,FER,GNB1,GNRH1,GPR83,GSK3A,HMGB2,HNRNPU,HSF1,KAT5,KIF18A,LANCL2,LYN,MBD4,MED1,NCOR1,NDEL1,NFE2L2,NFKB1,NOTCH1,NR2C2,NUCKS1,NUP62,PAK1,PHB2,PHIP,PTPN11,RAN,RANGAP1,RBBP4,RBBP8,RNF4,RNF40,RNF6,SIRT1,SLC25A33,SORD,SRSF4,STRN3,TSC1,UBE2I,UBE3A,UCP3,UFL1,YAP1,YY1 |
| GO_HEAD_DEVELOPMENT | 3.0e-07 | 5.3e-06 | 1930 | 774 | 60 | ANKRD11,ANP32B,ARCN1,ARHGAP11B,ATM,ATP5PB,ATXN1L,BAG3,BCAN,BRCA2,C12orf57,C2CD3,CASP3,CDK5RAP3,CEP120,CREB1,CSNK2A2,DMRTA2,DNAJB1,EZH1,FOXC1,GLUD1,KDM6B,MCPH1,MECP2,MED1,MTPN,NDEL1,NDUFS3,NOTCH1,NOTCH2NLA,PAK1,PCM1,PPP3CC,PTPN11,RAB18,RAB3GAP1,RAD1,RRM1,SEC24B,SLC7A11,SMG9,SNRPB,SYT1,TBR1,TBX3,TMEM108,TSC1,TYRO3,UBA6,UBB,UBE3A,WDR62,WNT9B,XAB2,ZEB2,ZFAND5,ZNF148,ZNF335,ZNF430 |
| GO_REGULATION_OF_BINDING | 3.0e-07 | 5.2e-06 | 1930 | 381 | 37 | ACD,AIDA,AURKB,BAG2,BTBD1,CDCA5,CDT1,CFHR2,CTBP2,DDX11,DOT1L,EIF3E,FMR1,FOXC1,GTF2F1,HJURP,HMGB2,HNRNPL,HSF1,ILRUN,KLF4,MAPK8,NEK2,NUCKS1,PEX14,PPP2CB,RAN,SMAD4,SUMO3,TCF7L2,TFIP11,TICAM1,TNKS,TRAF2,TRAF4,WAPL,ZNF675 |
| GO_MAINTENANCE_OF_CELL_NUMBER | 4.0e-07 | 5.6e-06 | 1930 | 163 | 22 | CNOT2,CNOT3,CUL4A,DPPA4,ELF5,KLF4,MCPH1,MED10,MED27,MED28,MED30,NKAP,NOTCH1,PAF1,PCM1,RIF1,SMAD4,SRRT,TAF5L,TBX3,WNT9B,YAP1 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 4.0e-07 | 5.7e-06 | 1930 | 351 | 35 | ADNP2,ATF4,ATM,BRF2,BTK,CASP3,CCNA2,CDK1,CDK2,DNAJA1,DNM2,FBXO7,FER,GSR,HSF1,IL18RAP,KDM6B,KLF4,MAPK8,MBIP,MELK,NFE2L2,NONO,OXR1,PAWR,PDCD10,PML,PPIF,PYROXD1,SIRT1,SLC7A11,SOD1,TRAF2,TSC1,ZNF622 |
| GO_POSITIVE_REGULATION_OF_GROWTH | 4.0e-07 | 5.7e-06 | 1930 | 275 | 30 | ADNP2,CCNB1,CDK1,CDKN2AIP,CREB1,DERL2,EDN1,EIF4G2,EXOSC4,EXOSC9,FGFR1OP,HSF1,ITSN2,MTPN,NDEL1,NOTCH1,PAK1,PARP2,PLAA,RUFY3,SFN,SLC25A33,SMURF1,SOX15,SUPV3L1,SYT1,TAF9B,USP47,YAP1,ZNF639 |
| GO_PROTEIN_DEPHOSPHORYLATION | 4.0e-07 | 5.6e-06 | 1930 | 320 | 33 | ANKLE2,CAMK2G,CDC25A,CDC25C,CTDSPL2,FBXW11,ILKAP,MASTL,MTMR2,MTMR6,PPM1A,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2CB,PPP2R1B,PPP2R5D,PPP2R5E,PPP3CC,PPP3R1,PPP4C,PPP4R2,PPP6R1,PTP4A1,PTP4A2,PTPN11,PTPN23,RPAP2,SET,TIMM50,TSC1 |
| GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 4.0e-07 | 5.6e-06 | 1930 | 447 | 41 | ABCA1,ABL2,ARFGEF2,ARHGEF38,BRAP,CCNA2,CDK2,CUL3,DNM2,FGD1,GNA13,GNB1,IQGAP3,ITSN2,KPNB1,LYN,MAP4K4,MFN2,NCKAP1,NOTCH1,NUP62,PPP2CB,RAB14,RAB15,RAB18,RAB1A,RAB21,RAB28,RAB35,RAB38,RABL3,RAP2C,RASA2,RASSF1,RIT1,RND3,SCAI,SETDB1,STK19,VAV2,WASF2 |
| GO_HISTONE_H3_ACETYLATION | 4.0e-07 | 5.8e-06 | 1930 | 60 | 13 | BRCA2,BRD1,CHEK1,DR1,KAT7,KMT2A,MBIP,SIRT1,SMAD4,SUPT7L,TADA1,TAF5L,TAF9B |
| GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION | 4.0e-07 | 5.8e-06 | 1930 | 60 | 13 | ATM,AURKB,BUB1,CCNB1,CDT1,CHEK1,DYNC1LI1,MTBP,NME6,PSMG2,RAD1,RAD21,TNKS |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 4.0e-07 | 5.7e-06 | 1930 | 960 | 70 | ATF2,ATXN1L,CCNA2,CCNB1,CD274,CDC6,CDK1,CDK2,CIP2A,CLCF1,CNOT6,CNOT6L,CUL3,CUL4A,DERL2,DMRTA2,DNAJA2,DOT1L,E2F3,EDN1,EIF5A,FER,FGFR1OP,FOXJ2,GID8,HIPK1,HMGB2,HNRNPU,HSF1,IQGAP3,KLB,LYN,MARCHF7,MECP2,MED1,MFN2,MTA3,N4BP2L2,NAP1L1,NOTCH1,PAK1,PDCD10,PDCL3,PGGT1B,PHIP,PML,PRC1,RICTOR,RNASEH2B,SINHCAF,SIRT1,SLC25A33,SLC25A5,SMAD4,SOX15,SPDYA,SSR1,SYF2,TBX3,TCF7L2,TIAL1,TICAM1,TMEM119,UBE2A,UFL1,WAPL,WDR48,YAP1,ZNF16,ZNF335 |
| GO_MITOTIC_CYTOKINESIS | 4.0e-07 | 5.9e-06 | 1930 | 70 | 14 | CENPA,CEP55,CHMP4B,CHMP5,CKAP2,CNTROB,ESPL1,INCENP,JTB,NUP62,NUSAP1,RAB35,RACGAP1,VPS4A |
| GO_INTERFERON_BETA_PRODUCTION | 4.0e-07 | 6.2e-06 | 1930 | 51 | 12 | CACTIN,HMGB2,NMI,POLR3C,POLR3F,PTPN11,REL,RIOK3,TICAM1,TRAIP,TRIM56,YY1 |
| GO_NEUROGENESIS | 4.0e-07 | 6.2e-06 | 1930 | 1625 | 104 | ABITRAM,ABL2,ADNP2,ALKBH1,ATF1,ATF4,BIN1,BLOC1S2,BTBD1,C12orf57,CAMSAP1,CASP3,CDK1,CDK5RAP3,CEP120,CLCF1,COPS2,CREB1,DENND5A,DMRTA2,DNM2,DVL3,EIF2B4,FBXO7,FMR1,GALR2,GNRH1,GSK3A,HDGFL3,HIPK1,HMGB2,IFRD1,ISL2,ITSN2,KLF4,LAMA2,LEMD2,LYN,MAP4K4,MAPK6,MECP2,MED1,MTCH1,MTMR2,MTPN,NAB1,NAP1L1,NCKAP1,NDEL1,NEPRO,NFE2L2,NGRN,NOTCH1,NRL,PAK1,PAK2,PARD3,PBX3,PCM1,PLAA,PQBP1,PRTG,PTPN11,RAB21,RAB35,RACGAP1,RNF10,RNF6,RPS6KA5,RUFY3,SEC24B,SF3A2,SH3KBP1,SIX4,SMAD4,SMURF1,SNW1,SOD1,SPART,SPINK5,SRRT,STRN,SYT1,TBR1,TCF3,TDP2,TMEM108,TSC1,TWF1,UBA6,UBB,UBE3A,UFL1,USP21,VAMP7,VAPA,WDR62,WEE1,WNT9B,YAP1,YTHDF2,ZEB1,ZEB2,ZNF335 |
| GO_MITOCHONDRIAL_GENE_EXPRESSION | 4.0e-07 | 6.7e-06 | 1930 | 165 | 22 | ALKBH1,HSD17B10,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTIF2,MTRF1L,NGRN,NSUN3,PUS1,QRSL1,RPUSD4,SLC25A33,SUPV3L1,TRMT10A,WARS2 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 5.0e-07 | 6.8e-06 | 1930 | 323 | 33 | ARL6IP1,BID,BLZF1,CHMP4B,GET3,GORASP2,MAIP1,MAPK8,NSG1,PAK1,PARD3,PPP3CC,PPP3R1,RAB3GAP1,RABGEF1,RPL21,RPL22,RPS7,SAMM50,SEC61A2,SEC62,SEC63,SFN,SRP72,SSR1,SSR2,SSR3,TFDP2,TIMM10,VAMP7,VPS35,VPS37A,ZDHHC18 |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 5.0e-07 | 7.0e-06 | 1930 | 569 | 48 | ABCA1,ABL2,ARFGEF2,ARHGAP11B,ARHGAP19,ARHGEF38,BRAP,CCNA2,CDK2,CUL3,DNM2,DOCK2,FGD1,GDI2,GNA13,GNB1,INPP5B,IQGAP3,ITSN2,KPNB1,LYN,MAP4K4,MFN2,NCKAP1,NOTCH1,NUP62,PPP2CB,RAB14,RAB15,RAB18,RAB1A,RAB21,RAB28,RAB35,RAB38,RABL3,RACGAP1,RAP2C,RAPGEFL1,RASA2,RASSF1,RIT1,RND3,SCAI,SETDB1,STK19,VAV2,WASF2 |
| GO_MRNA_3_SPLICE_SITE_RECOGNITION | 5.0e-07 | 7.4e-06 | 1930 | 6 | 5 | ISY1,SF1,SF3A2,SF3A3,SLU7 |
| GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_EXONUCLEOLYTIC | 5.0e-07 | 7.5e-06 | 1930 | 43 | 11 | CNOT2,CNOT6,CNOT6L,DCP2,DIS3,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,REXO2 |
| GO_TRANSCRIPTION_PREINITIATION_COMPLEX_ASSEMBLY | 5.0e-07 | 7.5e-06 | 1930 | 43 | 11 | BAZ2A,BRF2,CREB1,DR1,GTF3C3,MED6,PSMC2,PSMC3,PSMC4,PSMC6,TBPL2 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | 6.0e-07 | 8.4e-06 | 1930 | 72 | 14 | BAG3,BAG4,BAP1,BID,CSNK2A2,DNAJA1,GSK3A,MAPK8,PPP3CC,PPP3R1,RNF31,SFN,TFDP2,UBE2D3 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 6.0e-07 | 8.6e-06 | 1930 | 823 | 62 | AIDA,ANP32E,ARL6IP1,BAG2,BAG4,BCL2L12,BIN1,CASP3,CD2BP2,CDK5RAP3,CHORDC1,COL6A3,CPAMD8,DBNDD2,DNAJA1,DNAJB6,ELL,FBXO7,FGFR1OP,GALR2,GGNBP2,GLA,GSK3A,HNRNPU,IBTK,IPO7,IRAK3,KLF4,LYN,MASTL,MBIP,NFKB1,NOTCH1,NUP62,OAZ3,OR56A4,PAK2,PCDH11X,PPIF,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PRKRIP1,RBM26,RCC2,RPS7,SERPINC1,SET,SFN,SIRT1,SPINK5,TFIP11,TMED2,TSC1,UBE2Z,USP14,USP47,WASHC1,XIAP,ZNF675 |
| GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 6.0e-07 | 8.7e-06 | 1930 | 181 | 23 | BAG3,BAG4,BAP1,BID,COA8,CSNK2A2,FBXO7,GSK3A,MAPK8,MFN2,MYO19,PPIF,PPP3CC,PPP3R1,RNF31,SFN,SLC25A5,SMURF1,TFDP2,UBE2D3,USP30,VDAC1,VPS35 |
| GO_MONOUBIQUITINATED_PROTEIN_DEUBIQUITINATION | 6.0e-07 | 8.9e-06 | 1930 | 10 | 6 | ATXN3,BAP1,USP1,USP16,USP47,USP7 |
| GO_MITOCHONDRIAL_TRANSMEMBRANE_TRANSPORT | 6.0e-07 | 8.9e-06 | 1930 | 94 | 16 | ATP5F1B,ATP5MG,ATP5PB,CYC1,GRPEL1,GRPEL2,MAIP1,MCUR1,SLC25A28,SLC25A32,SLC25A33,SLC25A38,STOML2,TIMM44,TIMM50,UCP3 |
| GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 6.0e-07 | 9.0e-06 | 1930 | 83 | 15 | ADRM1,BRD4,CCNK,CCNT1,CCNT2,CDK12,EAF1,ELL,ELOA,GTF2F1,GTF2H2,HNRNPU,NELFA,PAF1,SUPT6H |
| GO_RNA_SURVEILLANCE | 6.0e-07 | 9.0e-06 | 1930 | 15 | 7 | EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,PRPF18,SUPV3L1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS | 6.0e-07 | 9.2e-06 | 1930 | 21 | 8 | ANP32B,BAG3,CTDSPL2,PPM1A,RBM22,SFN,TCF7L2,XPO4 |
| GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION | 6.0e-07 | 9.2e-06 | 1930 | 21 | 8 | AURKB,CDK1,CDT1,CENPA,CENPQ,MIS12,MTBP,RCC2 |
| GO_RESPONSE_TO_VIRUS | 6.0e-07 | 9.4e-06 | 1930 | 328 | 33 | CGAS,CRCP,CREBZF,DDX1,DDX60,EXOSC4,EXOSC5,FMR1,GPATCH3,GTF2F1,HNRNPUL1,ILF3,ILRUN,IRAK3,ITCH,LGALS8,MICB,NPLOC4,NT5C3A,PCBP2,PML,POLR3C,POLR3E,POLR3F,PQBP1,PSMA2,PUM1,PUM2,RIOK3,TICAM1,TRIM56,UFD1,ZC3HAV1 |
| GO_CELL_CELL_SIGNALING | 7.0e-07 | 1.0e-05 | 1930 | 1665 | 105 | AGO2,AP2B1,ATAD1,ATXN3,AXIN1,BCL7B,BTK,CAMK2G,CAPN10,CEP89,CGAS,CLTC,CREB1,CSNK1G1,CSNK2A2,CTBP2,CUL1,CUL3,DDB1,DGKZ,DVL3,EDN1,FBXW11,FMR1,FRZB,GABRG3,GID8,GLUD1,GNB1,GNRH1,GSK3A,HIC1,HSPA8,ITPR3,KDM6A,KLF4,KPNA2,LAMA2,LIN7C,LRRFIP2,LRRTM2,LYN,MECP2,MTMR2,MYLK2,NFKB1,NOTCH1,NSG1,OR56A4,PAF1,PFDN5,PPM1A,PPP3R1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTPN11,PTPN23,RAB11FIP2,RAB1A,RAB3GAP1,RNF138,RPL22,SH3KBP1,SLC25A5,SLC6A9,SLC7A11,SMAD4,SMURF1,STRN,SYT1,TBX3,TCF7L2,TMEM108,TNKS,UBB,UBC,USP14,USP47,VAMP7,VDAC1,VPS26A,VPS35,WNT9B,XIAP,YAP1,ZBTB33,ZEB2,ZNRF3 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING | 7.0e-07 | 1.1e-05 | 1930 | 36 | 10 | AGO2,CNOT10,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT9,PABPC1,TENT4A |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 8.0e-07 | 1.1e-05 | 1930 | 614 | 50 | ABCA1,ATF4,AXIN1,BCL2L2,CASP3,CASP7,CCNA2,CCNB1,CGAS,CNOT2,CNOT9,DAXX,DDX54,DNAJA1,DNM2,EDN1,EGLN2,ELK1,GNB1,GSK3A,HNRNPU,HSF1,KAT5,KIF18A,KLF4,MED1,NCOR1,NFKB1,NR2C2,NSG1,OR56A4,PAK1,PAK2,PHB2,PQBP1,RAD51,RAE1,RAN,RIOK3,RNF4,RNF6,SIRT1,SNW1,SOD1,STRN3,UBE2I,UBE3A,UFL1,VPS35,YAP1 |
| GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | 8.0e-07 | 1.2e-05 | 1930 | 45 | 11 | ATM,AURKB,BUB1,CCNB1,CDT1,DYNC1LI1,ESPL1,PSMG2,RAD21,TNKS,WAPL |
| GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 9.0e-07 | 1.2e-05 | 1930 | 227 | 26 | CACTIN,CCNK,GPATCH3,ILF3,ILRUN,IRAK3,ITCH,MICB,NMI,NPLOC4,NUCKS1,PARP14,PCBP2,PML,PSMC3,RIOK3,SETDB1,SPINK5,SRPK1,TYRO3,UFD1,VAPA,YTHDF2,YTHDF3,ZC3HAV1,ZNF639 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 9.0e-07 | 1.4e-05 | 1930 | 97 | 16 | CACTIN,GPATCH3,ILRUN,IRAK3,ITCH,MICB,NMI,NPLOC4,PARP14,PCBP2,RIOK3,SPINK5,TYRO3,UFD1,YTHDF2,YTHDF3 |
| GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 1.0e-06 | 1.4e-05 | 1930 | 37 | 10 | ACD,ATM,AURKB,DKC1,HNRNPA1,MAP2K7,NAF1,NEK2,NEK7,TNKS |
| GO_TRANSCRIPTION_BY_RNA_POLYMERASE_III | 1.0e-06 | 1.4e-05 | 1930 | 55 | 12 | BRF2,CRCP,ELL,GTF3C3,MAF1,POLR1D,POLR3C,POLR3E,POLR3F,RO60,SNAPC5,TBPL2 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1.0e-06 | 1.5e-05 | 1930 | 620 | 50 | AIDA,BAG2,C3orf33,CACTIN,CASP3,CCNB1,CDK5RAP3,CHORDC1,DBNDD2,DNAJA1,FBXO7,FGFR1OP,GGNBP2,IBTK,IPO7,IRAK3,ITCH,KLF4,LEMD2,LYN,MARCHF7,MASTL,MBIP,NCOR1,NUP62,OXR1,PAK2,PARD3,PARP14,PHF1,PLAA,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R5D,PRKRIP1,PWP1,RPS7,SET,SFN,SIRT1,SMAD4,SPOPL,SUPT6H,TERF2IP,TRIP12,UFL1,ZNF675 |
| GO_CYTOSKELETON_DEPENDENT_CYTOKINESIS | 1.1e-06 | 1.5e-05 | 1930 | 98 | 16 | ACTR3,AURKB,CENPA,CEP55,CHMP4B,CHMP5,CKAP2,CNTROB,ESPL1,INCENP,JTB,NUP62,NUSAP1,RAB35,RACGAP1,VPS4A |
| GO_KINETOCHORE_ASSEMBLY | 1.1e-06 | 1.5e-05 | 1930 | 16 | 7 | CENPA,CENPK,CENPT,CENPW,MIS12,RNF4,SENP6 |
| GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 1.2e-06 | 1.7e-05 | 1930 | 202 | 24 | BTK,CACTIN,CNPY3,CTSL,DDX60,GPATCH3,IRAK3,ITCH,LYN,NPLOC4,OTUD4,PUM1,PUM2,RAB11FIP2,RIOK3,TAB2,TICAM1,TNIP2,TYRO3,UBB,UBC,UBE2D3,UFD1,XIAP |
| GO_G0_TO_G1_TRANSITION | 1.3e-06 | 1.9e-05 | 1930 | 47 | 11 | CHEK1,L3MBTL2,MDM4,MED1,PHC3,RAD51,RBBP4,RBBP8,SOX15,TFDP2,YAF2 |
| GO_HORMONE_MEDIATED_SIGNALING_PATHWAY | 1.3e-06 | 1.9e-05 | 1930 | 232 | 26 | ADIPOR1,AXIN1,CNOT2,CNOT9,DAXX,DDX54,DNAJA1,EGLN2,KAT5,LANCL2,MED1,NCOR1,NR2C2,NUP62,PAK1,PHB2,PTPN11,RAN,RNF4,RNF6,SIRT1,STRN3,UBE2I,UBE3A,UFL1,YAP1 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 1.3e-06 | 1.9e-05 | 1930 | 1033 | 72 | ABHD3,ATM,ATP5F1B,ATP5MG,ATP5PB,BAAT,CAPN2,CDADC1,CSNK2A2,CTPS1,CYC1,DCK,DCTD,DGKZ,DHDDS,DOLPP1,FOXK2,GALR2,GDPD3,GMPS,HINT1,HKDC1,INPP5B,KLF4,LIPC,LYN,MBD4,MECP2,MOCOS,MTHFD1,MTMR2,MTMR6,NAPRT,NAXD,NME6,NT5C3A,NT5C3B,NUDT15,NUDT4,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PAPSS2,PFKFB3,PGAP2,PIPSL,PLAA,PLEKHA3,PLPP5,PNPLA8,PPCDC,RAB14,RAB38,RAE1,RAN,REXO2,RNASEH2B,RPIA,RRM1,SLC22A13,SLC4A1,SMG1,SOCS6,SORD,STOML2,TTC7B,UNG,VAV2,WASHC1 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 1.3e-06 | 1.8e-05 | 1930 | 30 | 9 | BRD4,CCNB1,CDC25A,CDC25C,CDK1,DTL,MECP2,MTA3,RCC2 |
| GO_RHYTHMIC_PROCESS | 1.4e-06 | 2.0e-05 | 1930 | 293 | 30 | AFP,ATF4,CASP3,CDK1,CLDN4,CREB1,CREBBP,CUL4A,DDB1,DTL,FBXL3,FBXW11,GNRH1,HNRNPL,HNRNPU,KDM2A,KMT2A,MAPK8,NCOR1,NDUFA9,NONO,PER3,PML,RBM4B,SIK1,SIRT1,TOP2A,TYRO3,UBE3A,USP7 |
| GO_MITOTIC_SPINDLE_ASSEMBLY | 1.5e-06 | 2.1e-05 | 1930 | 57 | 12 | ABRAXAS2,AURKB,CHMP4B,CHMP5,DRG1,HNRNPU,KPNB1,NEK2,RACGAP1,STAG1,STAG2,TPX2 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 1.5e-06 | 2.1e-05 | 1930 | 219 | 25 | ATXN3,AXIN1,BAG2,COP1,DDA1,DDB1,DTL,EGLN2,FAF1,FMR1,GSK3A,ITCH,NFE2L2,OAZ3,PSMC1,PSMC2,PSMC4,RCHY1,RHBDD3,RNF19B,RNF40,SMURF1,SUMO2,VPS35,ZFAND2A |
| GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY | 1.5e-06 | 2.1e-05 | 1930 | 57 | 12 | CELF1,DDX1,ISY1,KHDC4,LUC7L2,RBMX,SF1,SF3A2,SF3A3,SLU7,SRPK1,ZRSR2 |
| GO_IMPORT_INTO_NUCLEUS | 1.6e-06 | 2.2e-05 | 1930 | 164 | 21 | BAG3,FAM53C,HNRNPA1,IPO11,IPO7,KPNA2,KPNA4,KPNB1,MED1,NUP153,NUP50,NUP62,NXT1,PHB2,PML,RAB18,RAN,RBM22,RGPD6,SNRPB,TNPO2 |
| GO_UBIQUITIN_DEPENDENT_ERAD_PATHWAY | 1.6e-06 | 2.2e-05 | 1930 | 78 | 14 | AUP1,DERL2,DNAJB14,ECPAS,FBXO2,FBXO6,HSP90B2P,NFE2L2,NPLOC4,PSMC6,TMUB2,UBXN4,UBXN8,USP14 |
| GO_DNA_LIGATION | 1.7e-06 | 2.4e-05 | 1930 | 17 | 7 | APTX,HMGB2,PAXX,RAD51,TFIP11,TOP2A,XRCC4 |
| GO_MRNA_SPLICE_SITE_SELECTION | 1.7e-06 | 2.4e-05 | 1930 | 31 | 9 | CELF1,ISY1,KHDC4,LUC7L2,RBMX,SF1,SF3A2,SF3A3,SLU7 |
| GO_PROTEIN_DESUMOYLATION | 1.7e-06 | 2.3e-05 | 1930 | 7 | 5 | SENP1,SENP5,SENP6,SENP7,USPL1 |
| GO_PROTEIN_LOCALIZATION_TO_KINETOCHORE | 1.7e-06 | 2.4e-05 | 1930 | 17 | 7 | AURKB,CDK1,CDT1,CENPQ,MIS12,MTBP,RCC2 |
| GO_REGULATION_OF_DNA_DAMAGE_CHECKPOINT | 1.7e-06 | 2.4e-05 | 1930 | 17 | 7 | CUL4A,FEM1B,RFWD3,RNASEH2B,RPA2,THOC1,THOC5 |
| GO_ENDOPLASMIC_RETICULUM_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT | 1.8e-06 | 2.5e-05 | 1930 | 207 | 24 | ARCN1,CNIH1,CUL3,DCTN4,DCTN5,DCTN6,DYNC1LI1,ERGIC2,ERGIC3,GOSR1,KLHL21,PEF1,PPP6R1,RAB1A,SAR1A,SEC24B,SEC24C,STX18,TMED2,TMED5,TRAPPC10,VAMP7,VAPA,VTI1A |
| GO_REGULATION_OF_HISTONE_METHYLATION | 1.8e-06 | 2.4e-05 | 1930 | 68 | 13 | BRD4,KMT2A,KMT2B,MECP2,NSD3,PAF1,PHF1,RIF1,SIRT1,SMAD4,SNW1,SUPT6H,ZNF335 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 1.8e-06 | 2.4e-05 | 1930 | 561 | 46 | ACER1,APTX,ATF1,ATF2,ATF4,BAP1,CAPN2,CASP3,CCNA2,CCNB1,CDK1,CDK2,CREB1,DAXX,DDX11,DNM2,EDN1,FMR1,GNRH1,GSK3A,HNRNPA1,HSF1,IL18RAP,ITPR3,KDM6B,KLF4,KPNA4,MAPK8,NFE2L2,PAWR,PDCD10,PEF1,PPIF,PPP2CB,RAD51,SIRT1,SLC30A5,SLC41A1,SOD1,SORD,SUCNR1,SYT1,TRAF2,UBE3A,UCP3,XRCC4 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 1.9e-06 | 2.7e-05 | 1930 | 1318 | 86 | ADIPOR1,AKAP8,ARRDC3,ATF2,ATF4,BANK1,BIN1,BRCA2,BTK,CACTIN,CD200R1,CD274,CLEC4A,CUL4A,DENND5A,DPF2,EDN1,FBXO7,FOXC1,FOXJ2,FRZB,GLRX3,GNRH1,GPATCH3,GSK3A,H4-16,HGS,HOXA9,HSF1,HSPA9,IFRD1,ILRUN,IRAK3,ISL2,ITCH,KAT5,KLF4,LYN,MECP2,MED1,MTMR2,N4BP2L2,NEPRO,NFE2L2,NFKB1,NFKBID,NMI,NOTCH1,NPLOC4,OTUD7B,PAF1,PAK1,PCBP2,PCM1,PDCD10,PHB2,PML,PRTG,PTPN11,PTPN23,RBM15,RC3H1,REL,RNF10,RNF6,RPS6KA5,RUFY3,SIX4,SLC11A1,SMAD4,SMURF1,SOD1,SOX15,SPART,SPINK5,TAX1BP1,THBD,THOC1,TMEM119,TRAIP,TSC1,UBE3A,UFD1,WNT9B,YY1,ZNF675 |
| GO_VIRAL_GENE_EXPRESSION | 2.0e-06 | 2.7e-05 | 1930 | 194 | 23 | CCNT1,CCNT2,DENR,EIF3F,EIF3G,EIF3L,GTF2F1,NELFA,NUCKS1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PCBP2,PSMC3,RAE1,RPL21,RPL22,RPS7,SNW1,ZNF639 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | 2.1e-06 | 2.9e-05 | 1930 | 103 | 16 | ATM,BCL2L12,BCL2L2,BID,BRCA2,DYRK2,HIC1,HIPK1,HNRNPK,MARCHF7,PML,SFN,SIRT1,SNW1,TAF9B,USP47 |
| GO_PROTEIN_TARGETING_TO_VACUOLE | 2.1e-06 | 2.9e-05 | 1930 | 40 | 10 | AP3B1,HGS,HSPA8,SMURF1,SNX16,VAMP7,VPS37A,VPS4A,VTI1A,WASH3P |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 2.2e-06 | 3.0e-05 | 1930 | 1164 | 78 | AARSD1,ACO2,ADIPOR1,AKR1C1,AMT,AS3MT,AZIN1,BAAT,BCAN,BNIP2,CHST3,CLTC,CS,CTPS1,ECI1,EDN1,EEF1E1,ERO1B,FOXK2,GLUD1,GMPS,HKDC1,HMMR,HSD17B10,IDH3B,LIPC,MECP2,MRPS36,MTHFD1,NARS1,NFKB1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,OAZ3,PAPSS2,PDXDC1,PFKFB3,PLAA,PNPLA8,PRKAB1,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,PTS,QRSL1,RAE1,SEPHS1,SIRT1,SLC25A32,SLC4A1,SLC7A11,SORD,UCP3,UGDH,UGT2B7,VDAC1,VNN3,WARS2 |
| GO_REGULATION_OF_GENE_SILENCING | 2.2e-06 | 3.0e-05 | 1930 | 154 | 20 | AGO2,ATAD2,CDK2,FMR1,FXR1,H1-4,H4-16,MIER1,NCOR1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PUM1,PUM2,RAE1,SETDB1,SIRT1 |
| GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY | 2.2e-06 | 3.0e-05 | 1930 | 181 | 22 | AXIN1,CNOT2,CNOT9,DAXX,DDX54,DNAJA1,EGLN2,KAT5,MED1,NCOR1,NR2C2,PAK1,PHB2,RAN,RNF4,RNF6,SIRT1,STRN3,UBE2I,UBE3A,UFL1,YAP1 |
| GO_RESPONSE_TO_X_RAY | 2.3e-06 | 3.2e-05 | 1930 | 32 | 9 | ATM,BRCA2,CASP3,DNM2,ERCC8,NUCKS1,RAD51,THBD,XRCC4 |
| GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | 2.4e-06 | 3.3e-05 | 1930 | 104 | 16 | CCNT1,CHMP4B,DDB1,FMR1,GTF2F1,KPNA2,NELFA,NOTCH1,NUCKS1,PABPC1,SNW1,SRPK1,TOP2A,VAPA,VPS4A,ZNF639 |
| GO_HISTONE_MRNA_CATABOLIC_PROCESS | 2.5e-06 | 3.3e-05 | 1930 | 12 | 6 | ATM,DCP2,EXOSC10,EXOSC4,MTPAP,TENT4A |
| GO_REGULATION_OF_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE | 2.5e-06 | 3.3e-05 | 1930 | 12 | 6 | CCNB1,HNRNPU,KNSTRN,NEK2,RACGAP1,RCC2 |
| GO_SNORNA_3_END_PROCESSING | 2.5e-06 | 3.3e-05 | 1930 | 12 | 6 | DKC1,EXOSC10,EXOSC3,EXOSC4,EXOSC5,TENT4A |
| GO_CHAPERONE_MEDIATED_PROTEIN_FOLDING | 2.6e-06 | 3.6e-05 | 1930 | 60 | 12 | BAG1,CHORDC1,DNAJB1,DNAJB14,DNAJC7,HSPA14,HSPA6,HSPA8,HSPA9,HSPH1,PDCL3,ST13 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 2.7e-06 | 3.7e-05 | 1930 | 156 | 20 | CASP3,EIF2S3B,EIF3E,EIF5A,FMR1,FXR1,GSK3A,HNRNPL,NFE2L2,NGRN,PABPC1,PAIP1,POLDIP3,PPP1R15A,RPUSD4,UPF3B,USP16,YTHDF2,YTHDF3,ZCCHC4 |
| GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 2.7e-06 | 3.6e-05 | 1930 | 117 | 17 | BAP1,BID,COA8,CSNK2A2,FBXO7,GSK3A,MAPK8,MFN2,PPIF,PPP3CC,PPP3R1,RNF31,SFN,SMURF1,TFDP2,UBE2D3,VPS35 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 2.8e-06 | 3.8e-05 | 1930 | 143 | 19 | ATXN3,AXIN1,BAG2,COP1,DDA1,FAF1,FMR1,GSK3A,NFE2L2,PSMC1,PSMC2,PSMC4,RCHY1,RNF19B,RNF40,SMURF1,SUMO2,VPS35,ZFAND2A |
| GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 2.9e-06 | 3.9e-05 | 1930 | 25 | 8 | GPATCH3,ILRUN,ITCH,MICB,NPLOC4,PCBP2,RIOK3,UFD1 |
| GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 3.0e-06 | 4.0e-05 | 1930 | 273 | 28 | AZI2,BRD4,BTK,CASP10,DDX1,GPR89A,MIER1,NFKB1,NFKBID,NUP62,OTUD7B,PPM1A,REL,RIOK3,RNF31,SIRT1,SNIP1,TAB2,TERF2IP,TICAM1,TNIP2,TRAF2,TRAF5,UBB,UBC,UBE2I,VAPA,ZNF675 |
| GO_ELECTRON_TRANSPORT_CHAIN | 3.1e-06 | 4.2e-05 | 1930 | 185 | 22 | AIFM2,ALDH2,BID,CCNB1,CDK1,COA6,COX5A,CYC1,GLRX3,GSR,IDH3B,MECP2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,RDH16,TSTA3,UQCRC2,UQCRH |
| GO_REPLICATION_FORK_PROCESSING | 3.1e-06 | 4.1e-05 | 1930 | 33 | 9 | ALYREF,BRCA2,DDX11,FANCM,MMS22L,NUCKS1,RAD51,RFWD3,THOC1 |
| GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR | 3.2e-06 | 4.2e-05 | 1930 | 51 | 11 | DTL,NPLOC4,POLE,POLK,RCHY1,RFC1,RPA2,SIRT1,UBB,UBC,UFD1 |
| GO_NUCLEAR_ENVELOPE_ORGANIZATION | 3.2e-06 | 4.2e-05 | 1930 | 51 | 11 | AKAP8L,ANKLE2,CCNB1,CCNB2,CDK1,CHMP4B,LEMD2,NDEL1,NSFL1C,TMEM170A,VPS4A |
| GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE | 3.2e-06 | 4.2e-05 | 1930 | 51 | 11 | ACD,ATM,AURKB,DKC1,HNRNPA1,MAP2K7,NAF1,NEK2,NEK7,PML,TNKS |
| GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 3.2e-06 | 4.2e-05 | 1930 | 106 | 16 | CASP3,CCNA2,CCNB1,CCNB2,CCNK,CCNL1,CCNT1,CCNT2,CDC25A,CDC25C,CDC6,CDK5RAP3,FBXO7,IPO7,SFN,SPDYA |
| GO_DEFENSE_RESPONSE_TO_VIRUS | 3.4e-06 | 4.4e-05 | 1930 | 244 | 26 | CGAS,CRCP,DDX1,DDX60,EXOSC4,EXOSC5,GPATCH3,ILF3,ILRUN,ITCH,MICB,NPLOC4,NT5C3A,PCBP2,PML,POLR3C,POLR3E,POLR3F,PQBP1,PUM1,PUM2,RIOK3,TICAM1,TRIM56,UFD1,ZC3HAV1 |
| GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY | 3.4e-06 | 4.5e-05 | 1930 | 42 | 10 | ALYREF,BRCA2,DDX11,FANCM,MMS22L,NUCKS1,POLE,RAD51,RFWD3,THOC1 |
| GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION | 3.4e-06 | 4.5e-05 | 1930 | 42 | 10 | BRD4,KMT2A,MECP2,NSD3,PAF1,PHF1,RIF1,SIRT1,SMAD4,SNW1 |
| GO_REGULATION_OF_MACROAUTOPHAGY | 3.4e-06 | 4.5e-05 | 1930 | 172 | 21 | ATP6V0A2,ATP6V1G1,ATP6V1H,BAG3,CASP3,CHMP4B,MAPK8,MFN2,PRKAB1,RAB3GAP1,SIRT1,SLC38A9,SMURF1,SNX5,TSC1,UBQLN4,USP30,UVRAG,VPS26A,VPS35,WAC |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 3.5e-06 | 4.6e-05 | 1930 | 984 | 68 | ABCA1,ANP32B,AP1G1,AP2B1,ARL6IP1,ATAD1,ATF4,AZIN1,BAG3,BAP1,BID,CAPN10,CBLL1,CD274,CLASP2,COA8,CPSF6,CREB1,CSNK2A2,CTDSPL2,DNM2,DOCK2,EDN1,FMR1,GALR2,GLUD1,GSK3A,HGS,HNRNPK,KMT2A,MAPK8,MTMR2,NFE2L2,PAK1,PCM1,PDCD10,PLAA,PPM1A,PPP3CC,PPP3R1,PTPN11,PTPN23,RAB15,RAB21,RAB3GAP1,RAN,RBM22,RBM26,RBM27,RNF31,RUFY3,SAR1A,SFN,SIRT1,SLC11A1,SMAD4,SNX5,SOD1,STAM,STX18,SYT1,TCF7L2,TFDP2,UBE2D3,VAMP7,VPS35,VPS4A,XPO4 |
| GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 3.9e-06 | 5.1e-05 | 1930 | 231 | 25 | AATF,BCL2L12,BCL2L2,BID,CSNK2A2,DNAJA1,GFRAL,HMGB2,MARCHF7,NDUFS3,NFE2L2,NONO,PEA15,PHIP,PPIF,SIRT1,SLC25A5,TAF9B,TCF7L2,TNFRSF10A,TRAF2,USP47,VDAC2,YAP1,ZC3HC1 |
| GO_POSTREPLICATION_REPAIR | 3.9e-06 | 5.0e-05 | 1930 | 52 | 11 | DTL,NPLOC4,POLK,RAD18,RCHY1,RFC1,RPA2,UBB,UBC,UBE2A,UFD1 |
| GO_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 4.0e-06 | 5.2e-05 | 1930 | 491 | 41 | AP1G1,AP3B1,ATM,BANK1,BTK,CASP3,CD274,CGAS,CLCF1,EXOSC3,FBXO7,GNRH1,HSPH1,IGHV3-43,LYN,MARCHF7,NFKBID,NKAP,NSD2,PAK1,PAK2,PAWR,PTPN11,RC3H1,RHBDD3,RIF1,SART1,SH3KBP1,SHLD1,SHLD2,SOCS6,SOD1,SPINK5,SUPT6H,THOC1,TICAM1,TNIP2,TYRO3,YES1,ZEB1,ZNF335 |
| GO_NEGATIVE_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | 4.3e-06 | 5.6e-05 | 1930 | 8 | 5 | DPF2,HSPA9,N4BP2L2,NFE2L2,NOTCH1 |
| GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 4.5e-06 | 5.8e-05 | 1930 | 63 | 12 | DDX60,GPATCH3,ITCH,NPLOC4,PUM1,PUM2,RIOK3,TAB2,UBB,UBC,UFD1,XIAP |
| GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 4.5e-06 | 5.8e-05 | 1930 | 63 | 12 | ANP32B,BAG3,CPSF6,CTDSPL2,PPM1A,RAN,RBM22,RBM26,RBM27,SFN,TCF7L2,XPO4 |
| GO_REGULATION_OF_HISTONE_PHOSPHORYLATION | 4.5e-06 | 5.8e-05 | 1930 | 13 | 6 | AKAP8,AKAP8L,ATM,CCNB1,FMR1,RPS6KA5 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 4.6e-06 | 6.0e-05 | 1930 | 1208 | 79 | ABCA1,ABL2,ADIPOR1,ADNP2,AKAP8,AKR1C1,ATF4,ATM,ATP6V0A2,ATP6V1G1,ATP6V1H,BAIAP2L1,BCL2L2,BTK,CACTIN,CAPN10,CAPN2,CCNA2,CCNB1,CD274,CDC6,CDK1,CDK2,CHMP5,CPEB1,CREB1,DDX11,DNM2,EDN1,ELK1,FER,GNB1,GSK3A,HMGB2,HSF1,IL18RAP,KAT5,KDM6B,KIF18A,KLF4,LANCL2,LYN,MAPK8,MED1,NDEL1,NFE2L2,NFKB1,NFKBIB,NSG1,NUCKS1,OR56A4,OXR1,PABPN1,PAF1,PAK1,PAWR,PDCD10,PHB2,PHIP,PLAA,PPIF,PTPN11,RAB11FIP2,RAD51,RANGAP1,SIRT1,SLC25A33,SLC38A9,SNW1,SOD1,TICAM1,TNIP2,TRAF2,TSC1,VPS35,WNT9B,YAP1,YES1,ZEB1 |
| GO_ATP_SYNTHESIS_COUPLED_ELECTRON_TRANSPORT | 4.7e-06 | 6.0e-05 | 1930 | 97 | 15 | BID,CCNB1,CDK1,COA6,COX5A,CYC1,MECP2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,UQCRC2,UQCRH |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 4.7e-06 | 6.0e-05 | 1930 | 1051 | 71 | ACTR3,ADIPOR1,AFP,AP2B1,APH1A,ATP6V0A2,ATP6V1G1,ATP6V1H,BAIAP2L1,CASP3,CEP57,CNOT9,CREB1,CREBBP,CTDSPL2,DNM2,FAM83B,FER,FGF22,FOXC1,FRS3,GFRAL,GIGYF1,GSK3A,GTF2F1,HGS,HNRNPA1,HNRNPH1,KLB,LEMD2,LRIT3,LYN,NCKAP1,NDEL1,NOTCH1,NUCKS1,NUP62,PAK1,PAK2,PARD3,PHIP,PML,PPM1A,PTPN11,RAB14,RNF126,RPS6KA5,SH2B1,SH3KBP1,SHCBP1,SIRT1,SMAD4,SMURF1,SNW1,SNX5,SPART,STAM,TIAL1,TMEM108,TSC1,TYRO3,UBB,UBC,UBE2D3,VAV2,WASF2,XIAP,YES1,ZC3H3,ZEB1,ZFAND5 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | 4.7e-06 | 6.0e-05 | 1930 | 74 | 13 | ATMIN,CEP120,CEP135,CNOT2,CNOT6,CNOT6L,EDN1,LCP1,MNS1,NUP62,PLK4,RAB3GAP1,STX18 |
| GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 4.7e-06 | 6.0e-05 | 1930 | 74 | 13 | CGAS,DDX60,GPATCH3,ILRUN,ITCH,MICB,NPLOC4,PCBP2,PQBP1,PUM1,PUM2,RIOK3,UFD1 |
| GO_SOMATIC_RECOMBINATION_OF_IMMUNOGLOBULIN_GENE_SEGMENTS | 4.7e-06 | 6.0e-05 | 1930 | 53 | 11 | CLCF1,EXOSC3,NSD2,RIF1,SHLD1,SHLD2,SUPT6H,TCF3,THOC1,UNG,XRCC4 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS_INVOLVED_IN_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 4.8e-06 | 6.1e-05 | 1930 | 122 | 17 | ATXN3,AXIN1,BAG2,COP1,DDA1,FMR1,GSK3A,NFE2L2,PSMC1,PSMC2,PSMC4,RCHY1,RNF19B,RNF40,SMURF1,SUMO2,ZFAND2A |
| GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | 4.9e-06 | 6.2e-05 | 1930 | 219 | 24 | CAMSAP1,CKAP2,CKAP5,CLASP2,EIF5A,GSPT1,HDGFL3,HSPA8,KIF18A,KIF2C,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTPN,MTRF1L,OGFOD1,PEX14,TWF1,VPS4A |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 5.1e-06 | 6.5e-05 | 1930 | 767 | 56 | ABL2,ACAP2,ADRM1,AGAP6,AHSA2P,ANP32B,ARHGAP11B,ARHGAP19,BID,BNIP2,CASP10,CLDN4,COA8,DDX11,DENND1B,DEPDC1,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC9,DOCK2,DVL3,GDI2,GNA13,GTF2H2,HMGB2,HNRNPU,HSCB,HSF1,KHDC1L,LYN,MAP4K4,MAPK8,MTCH1,NCAPH,NDEL1,PLAA,PML,PPP1R15A,PSME2,RAB11FIP2,RAB3GAP1,RACGAP1,RANGAP1,RASA2,RCC2,RGPD6,SENP1,SIRT1,TBC1D15,TBC1D22B,TNFRSF10A,TRAF2,TSC1,ZC3H15 |
| GO_NEGATIVE_REGULATION_OF_DNA_REPAIR | 5.3e-06 | 6.7e-05 | 1930 | 35 | 9 | CGAS,HELB,HSF1,RIF1,SHLD1,SHLD2,TFIP11,TRIP12,UBQLN4 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_EXONUCLEOLYTIC | 5.3e-06 | 6.7e-05 | 1930 | 35 | 9 | CNOT6,DCP1A,DCP2,DIS3,EXOSC3,EXOSC4,EXOSC5,EXOSC9,NT5C3B |
| GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 5.5e-06 | 7.0e-05 | 1930 | 586 | 46 | AGO2,ATAD2,BAZ2A,CELF1,CHEK1,CNOT6,CREBZF,DOT1L,EXOSC10,EZH1,FAM172BP,FMR1,FXR1,GSK3A,H1-4,H4-16,HAT1,HNRNPU,KMT2B,LRIF1,MECP2,MIER1,MSL3,NCOR1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PCGF5,PHF1,PUM1,PUM2,RAE1,RAN,RBBP4,RBM15,RIF1,RLIM,SETDB1,SIRT1,SNIP1,SRRT,ZC3H7A,ZNF335 |
| GO_REGULATION_OF_SPINDLE_ASSEMBLY | 5.6e-06 | 7.0e-05 | 1930 | 27 | 8 | CHMP4B,CHMP5,DRG1,HNRNPU,RNF4,SENP6,STAG1,STAG2 |
| GO_OVARIAN_FOLLICLE_DEVELOPMENT | 5.7e-06 | 7.2e-05 | 1930 | 54 | 11 | ATM,DMC1,EIF2B4,FANCG,FOXC1,GNRH1,KMT2B,MSH4,SMAD4,SOD1,UBE3A |
| GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | 6.0e-06 | 7.6e-05 | 1930 | 124 | 17 | AIFM2,ATF2,BID,BLOC1S2,COA8,GSK3A,JTB,MAPK8,PPIF,PPP2CB,PPP3CC,PPP3R1,SFN,SLC25A5,TFDP2,TIMM50,VPS35 |
| GO_CIRCADIAN_RHYTHM | 6.0e-06 | 7.6e-05 | 1930 | 207 | 23 | ATF4,CDK1,CLDN4,CREB1,DDB1,FBXL3,FBXW11,HNRNPL,HNRNPU,KDM2A,KMT2A,MAPK8,NCOR1,NDUFA9,NONO,PER3,PML,RBM4B,SIK1,SIRT1,TOP2A,UBE3A,USP7 |
| GO_ERROR_FREE_TRANSLESION_SYNTHESIS | 6.3e-06 | 7.9e-05 | 1930 | 20 | 7 | NPLOC4,RCHY1,RFC1,RPA2,UBB,UBC,UFD1 |
| GO_HEART_DEVELOPMENT | 6.3e-06 | 7.9e-05 | 1930 | 589 | 46 | ADAMTS6,AP2B1,ATF2,ATM,C2CD3,CASP3,CCNB1,CDK1,CDKL1,CREB1,DCTN5,DNM2,EDN1,FOXC1,GSK3A,HNRNPU,JMJD6,KDM6A,KDM6B,LEMD2,MATR3,MDM4,MED1,MTERF4,MTHFD1,MYLK2,NOTCH1,NSD2,PAK1,PARP2,POPDC2,PTPN11,RBM15,SEC24B,SIK1,SMAD4,SMG9,TAB2,TBR1,TBX3,TFDP2,TMED2,TSC1,YAP1,YY1,ZBTB14 |
| GO_HISTONE_H4_ACETYLATION | 6.4e-06 | 8.0e-05 | 1930 | 65 | 12 | ACTL6A,BRCA2,HAT1,ING3,KANSL1,KANSL2,KAT5,KAT7,KMT2A,MSL2,MSL3,SIRT1 |
| GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 6.4e-06 | 8.0e-05 | 1930 | 76 | 13 | AXIN1,CNOT2,CNOT9,MED1,NCOR1,PAK1,PHB2,RNF6,SIRT1,STRN3,UBE2I,UFL1,YAP1 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR | 6.6e-06 | 8.2e-05 | 1930 | 45 | 10 | BCL2L12,BRCA2,DYRK2,HIPK1,HNRNPK,MARCHF7,PML,SIRT1,SNW1,TAF9B |
| GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION | 6.6e-06 | 8.2e-05 | 1930 | 45 | 10 | CGAS,H1-4,HELB,RIF1,SHLD1,SHLD2,TERF2IP,THOC1,UBQLN4,ZSCAN4 |
| GO_PEPTIDYL_LYSINE_TRIMETHYLATION | 6.6e-06 | 8.2e-05 | 1930 | 45 | 10 | BRD4,H1-4,KMT2A,KMT2B,MECP2,NSD3,PWP1,SIRT1,TET3,ZNF335 |
| GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 6.7e-06 | 8.3e-05 | 1930 | 125 | 17 | ARAF,COP1,DDA1,GSK3A,NFE2L2,RCHY1,RNF19B,SENP1,SUMO2,TLK2,UBE2K,UBQLN4,UFL1,USP14,USP7,WAC,ZFAND2A |
| GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY | 6.8e-06 | 8.4e-05 | 1930 | 36 | 9 | ACD,AURKB,DKC1,KLF4,MAP2K7,NAF1,NEK2,NEK7,TNKS |
| GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | 6.9e-06 | 8.5e-05 | 1930 | 88 | 14 | BRMS1,CACTIN,CDK5RAP3,FAF1,IRAK3,ITCH,KLF4,NFKBID,SIRT1,TAX1BP1,TRAIP,UFL1,USP7,ZNF675 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 6.9e-06 | 8.5e-05 | 1930 | 100 | 15 | ATM,BABAM1,DDX11,EEF1E1,EID3,ERCC8,FMR1,FXR1,HIC1,RIF1,SHLD1,SHLD2,SIRT1,SLF1,UIMC1 |
| GO_TELOMERE_CAPPING | 6.9e-06 | 8.5e-05 | 1930 | 55 | 11 | ACD,ATM,AURKB,H4-16,MAP2K7,NEK2,NEK7,TERF2IP,TFIP11,TNKS,USP7 |
| GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL | 7.1e-06 | 8.7e-05 | 1930 | 209 | 23 | ABCA1,ABL2,ADNP2,AKAP8,AKR1C1,ATM,CAPN2,CCNB1,CPEB1,CREB1,EDN1,GNB1,HSF1,KLF4,LANCL2,LYN,PHB2,SLC38A9,SNW1,WNT9B,YAP1,YES1,ZEB1 |
| GO_REGULATION_OF_DEPHOSPHORYLATION | 7.1e-06 | 8.7e-05 | 1930 | 209 | 23 | ANKLE2,BAG4,CD2BP2,CDK5RAP3,ELL,MASTL,MTMR2,PCDH11X,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R1B,PPP2R5D,PPP2R5E,PPP4R2,PPP6R1,RBM26,SET,SMG5,SMG7,TSC1 |
| GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 7.4e-06 | 9.1e-05 | 1930 | 77 | 13 | CGAS,CRCP,CREBBP,HMGB2,LRRFIP1,NFKB1,POLR3C,POLR3E,POLR3F,PQBP1,PTPN11,RIOK3,TICAM1 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 7.7e-06 | 9.4e-05 | 1930 | 153 | 19 | ANP32B,BAG3,BAP1,CSNK2A2,CTDSPL2,GSK3A,PAK1,PCM1,PDCD10,PPM1A,RAN,RBM22,RNF31,RUFY3,SAR1A,SFN,TCF7L2,UBE2D3,XPO4 |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 7.9e-06 | 9.6e-05 | 1930 | 1428 | 89 | ABL2,AGO2,AP3B1,ATF1,ATF4,ATXN1L,BIN1,BNIP2,BTK,CAPN2,CCNB1,CD274,CDK1,CGAS,CLASP2,CLCF1,CREB1,DMRTA2,DNM2,DVL3,EDN1,EEF1E1,ERAP1,EXOSC3,FMR1,FOXC1,FRZB,HIPK1,HMGB2,HNRNPU,HOXA11,HOXC11,HSF1,IQGAP3,IRAK3,ITSN2,KLF4,LRRTM2,LYN,MAPK6,MED1,N4BP2L2,NAP1L1,NDEL1,NFE2L2,NFKB1,NFKBID,NKAP,NOTCH1,NR2C2,NSD2,NUDT21,PAK1,PARD3,PARP2,PAWR,PDCL3,PLAA,PWP1,RAB21,RIF1,RNF10,RUFY3,SART1,SF3A2,SFN,SHLD1,SHLD2,SIRT1,SIX4,SMAD4,SMURF1,SNW1,SOX15,SRPX2,SRRT,SYT1,TCF3,TCF7L2,TMEM119,TWF1,UFL1,VAMP7,VPS35,YAP1,ZEB1,ZEB2,ZNF16,ZNF335 |
| GO_REGULATION_OF_CYTOKINESIS | 7.9e-06 | 9.6e-05 | 1930 | 89 | 14 | AURKB,BRCA2,CDC6,CSPP1,CUL3,INCENP,KLHL21,MYO19,NUP62,PLK4,PRC1,RACGAP1,UVRAG,VPS4A |
| GO_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY | 8.3e-06 | 1.0e-04 | 1930 | 56 | 11 | AXIN1,CNOT2,CNOT9,DDX54,EGLN2,MED1,PAK1,PHB2,STRN3,UFL1,YAP1 |
| GO_PROTEIN_K48_LINKED_UBIQUITINATION | 8.3e-06 | 1.0e-04 | 1930 | 56 | 11 | ITCH,NMI,RNF126,RNF4,RNF6,UBE2A,UBE2C,UBE2D3,UBE2K,UBE2T,UBE3A |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR | 8.6e-06 | 1.0e-04 | 1930 | 78 | 13 | BCL2L12,BRCA2,DYRK2,HINT1,HIPK1,HNRNPK,MARCHF7,PML,RPS7,SIRT1,SNW1,TAF9B,UBB |
| GO_CELLULAR_COMPONENT_DISASSEMBLY_INVOLVED_IN_EXECUTION_PHASE_OF_APOPTOSIS | 8.7e-06 | 1.1e-04 | 1930 | 37 | 9 | CAPN10,CASP3,CDK5RAP3,DFFB,EXOG,HMGB2,HSF1,KPNB1,TOP2A |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II | 8.8e-06 | 1.1e-04 | 1930 | 102 | 15 | AP1G1,AP2B1,CLTA,CLTC,CTSL,DCTN4,DCTN5,DCTN6,DNM2,DYNC1LI1,KIF18A,KIF2C,RACGAP1,SEC24B,SEC24C |
| GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 8.8e-06 | 1.1e-04 | 1930 | 67 | 12 | ACD,ATM,AURKB,CHTF18,DKC1,HNRNPA1,KLF4,MAP2K7,NAF1,NEK2,NEK7,TNKS |
| GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 8.8e-06 | 1.1e-04 | 1930 | 455 | 38 | AP1G1,BTK,C12orf4,CD226,CFHR2,CGAS,CLCF1,DDX1,DDX60,EXOSC3,FER,GPATCH3,IGKV1D-33,IL18RAP,ILRUN,IRAK3,ITCH,LYN,MICB,NFKBID,NPLOC4,NSD2,PCBP2,PQBP1,PUM1,PUM2,RC3H1,RIF1,RIOK3,SHLD1,SHLD2,SPINK5,SUPT6H,THOC1,TICAM1,TRAF2,UFD1,VAMP7 |
| GO_VACUOLAR_TRANSPORT | 9.0e-06 | 1.1e-04 | 1930 | 141 | 18 | AP1G1,AP3B1,BIN1,CHMP4B,CHMP4BP1,CHMP5,HGS,HSPA8,RBSN,SMURF1,SNX16,VAMP7,VPS35,VPS37A,VPS4A,VPS51,VTI1A,WASH3P |
| GO_NEGATIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | 9.1e-06 | 1.1e-04 | 1930 | 21 | 7 | HNRNPK,HNRNPL,RBM10,RBM42,RBMX,RNPS1,SRSF4 |
| GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 9.1e-06 | 1.1e-04 | 1930 | 21 | 7 | CDK12,HNRNPU,HSPA9,N4BP2L2,NFE2L2,NOTCH1,YAP1 |
| GO_REGULATION_OF_VIRAL_INDUCED_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 9.1e-06 | 1.1e-04 | 1930 | 21 | 7 | DDX60,GPATCH3,NPLOC4,PUM1,PUM2,RIOK3,UFD1 |
| GO_RESPIRATORY_ELECTRON_TRANSPORT_CHAIN | 9.3e-06 | 1.1e-04 | 1930 | 115 | 16 | AIFM2,BID,CCNB1,CDK1,COA6,COX5A,CYC1,MECP2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,UQCRC2,UQCRH |
| GO_GOLGI_ORGANIZATION | 9.9e-06 | 1.2e-04 | 1930 | 142 | 18 | BLZF1,CDK1,CLASP2,DNM2,GOLGA8H,GORASP2,NPLOC4,NSFL1C,PDCD10,RAB1A,RBSN,STX16,STX18,TJAP1,TMED2,TMED5,VPS51,VTI1A |
| GO_POSITIVE_REGULATION_OF_TRANSLATION | 1.0e-05 | 1.2e-04 | 1930 | 129 | 17 | EIF2S3B,EIF3E,EIF5A,FMR1,FXR1,HNRNPL,NGRN,PABPC1,PAIP1,POLDIP3,PPP1R15A,RPUSD4,UPF3B,USP16,YTHDF2,YTHDF3,ZCCHC4 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1.0e-05 | 1.2e-04 | 1930 | 767 | 55 | AKAP8L,ANP32B,ATAD1,BAG3,BAG4,BANK1,BAP1,BID,CAPN10,CD200R1,CD274,CEP120,CEP135,CSNK2A2,CTDSPL2,DERL2,DKC1,DNAJA1,GLUD1,GSK3A,HSPA8,ITPR3,LCP1,LYN,MAPK8,NDEL1,NSD2,NUP62,PAK1,PCM1,PDCD10,PML,PPM1A,PPP3CC,PPP3R1,PTPN11,PTPN23,RAN,RANGAP1,RBM22,RHBDD3,RNF31,RUFY3,SAR1A,SFN,SLC25A5,SLC7A11,SUPT6H,TCF7L2,TFDP2,TRAF2,UBE2D3,VAMP7,VPS35,XPO4 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 1.1e-05 | 1.3e-04 | 1930 | 1117 | 73 | AATF,AGO2,AKR1C1,ALG13,ALG5,ATP5F1B,ATP5MG,ATP5PB,BAAT,BCAN,CDADC1,CHST3,CLN6,CLTC,CTPS1,CYC1,DCK,DCTD,DERL2,DHDDS,DOLPP1,FBXO2,FBXO6,FOXC1,FOXK2,GALC,GLA,GMPPB,GMPS,GSK3A,HINT1,HKDC1,HMMR,MBD4,MPDU1,MUC13,NFKB1,NME6,NT5C3A,NUDT15,NUDT4,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PAPSS2,PAWR,PFKFB3,PGAP2,POFUT2,POMT2,PPCDC,RAB1A,RAE1,RAN,RNASEH2B,RPIA,RRM1,SLC4A1,SORD,ST8SIA4,ST8SIA5,STOML2,STT3A,TCF7L2,TET3,TGDS,TSTA3,TYW3,UGDH,UNG |
| GO_NCRNA_EXPORT_FROM_NUCLEUS | 1.1e-05 | 1.3e-04 | 1930 | 38 | 9 | NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,RAE1,RAN,TSC1 |
| GO_NEGATIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 1.1e-05 | 1.3e-04 | 1930 | 171 | 20 | BRMS1,CACTIN,CDK5RAP3,FAF1,IRAK3,ITCH,KLF4,MED13,NFKBID,PEX14,PHB2,RLIM,SIK1,SIRT1,TAX1BP1,TCF7L2,TRAIP,UFL1,USP7,ZNF675 |
| GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 1.1e-05 | 1.3e-04 | 1930 | 130 | 17 | ATAD2,BAZ2A,CREBZF,DOT1L,EZH1,FAM172BP,H1-4,H4-16,HAT1,MECP2,MIER1,MSL3,PHF1,RBBP4,RIF1,SETDB1,SIRT1 |
| GO_PROTEIN_STABILIZATION | 1.1e-05 | 1.3e-04 | 1930 | 185 | 21 | BAG2,BAG3,COA8,CREB1,DVL3,HSP90AA2P,HSP90AA4P,HSP90AB4P,MARCHF7,MDM4,PDCD10,PDCL3,PER3,PHB2,RPS7,TAF9B,TBRG1,TELO2,TNIP2,TSC1,USP7 |
| GO_REGULATION_OF_CELL_ACTIVATION | 1.1e-05 | 1.2e-04 | 1930 | 619 | 47 | AP1G1,AP3B1,ATM,BANK1,BTK,C12orf4,CASP3,CD226,CD274,CGAS,CLCF1,EXOSC3,FBXO7,FER,GNRH1,HSPH1,IGHV3-43,LYN,MARCHF7,NFKBID,NKAP,NSD2,PAK1,PAK2,PAWR,PTPN11,RC3H1,RHBDD3,RIF1,SART1,SH3KBP1,SHLD1,SHLD2,SOCS6,SOD1,SOX15,SPINK5,SUPT6H,THBD,THOC1,TICAM1,TNIP2,TYRO3,VAMP7,YES1,ZEB1,ZNF335 |
| GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION | 1.2e-05 | 1.4e-04 | 1930 | 69 | 12 | ATM,DNM2,ELK1,HSF1,INTS7,NUCKS1,RAD1,RAD51,RAD51AP1,SIRT1,TLK2,YAP1 |
| GO_CELLULAR_RESPONSE_TO_RETINOIC_ACID | 1.2e-05 | 1.4e-04 | 1930 | 69 | 12 | ABCA1,ABL2,ADNP2,ATM,CREB1,KLF4,LYN,PHB2,SNW1,WNT9B,YAP1,YES1 |
| GO_CENTROSOME_SEPARATION | 1.2e-05 | 1.4e-04 | 1930 | 15 | 6 | CHEK1,CNTROB,NDEL1,NEK2,NSFL1C,NUP62 |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | 1.2e-05 | 1.4e-04 | 1930 | 58 | 11 | BAP1,BID,CSNK2A2,GSK3A,MAPK8,PPP3CC,PPP3R1,RNF31,SFN,TFDP2,UBE2D3 |
| GO_POSITIVE_REGULATION_OF_VIRAL_LIFE_CYCLE | 1.2e-05 | 1.4e-04 | 1930 | 58 | 11 | CHMP4B,DDB1,FMR1,KPNA2,NOTCH1,NUCKS1,PABPC1,SRPK1,TOP2A,VAPA,VPS4A |
| GO_REGULATION_OF_CENTROSOME_CYCLE | 1.2e-05 | 1.4e-04 | 1930 | 58 | 11 | CEP120,CEP76,CHEK1,CHMP4B,CHMP5,CHORDC1,MCPH1,NEK2,NSFL1C,NUP62,PLK4 |
| GO_REGULATION_OF_RNA_POLYMERASE_II_TRANSCRIPTIONAL_PREINITIATION_COMPLEX_ASSEMBLY | 1.2e-05 | 1.4e-04 | 1930 | 15 | 6 | CREB1,DR1,PSMC2,PSMC3,PSMC4,PSMC6 |
| GO_CELLULAR_RESPIRATION | 1.3e-05 | 1.5e-04 | 1930 | 187 | 21 | ACO2,AIFM2,BID,CCNB1,CDK1,COA6,COX5A,CS,CYC1,IDH3B,MECP2,MTFR2,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,SLC25A25,UQCRC2,UQCRH |
| GO_MITOTIC_G2_M_TRANSITION_CHECKPOINT | 1.3e-05 | 1.5e-04 | 1930 | 30 | 8 | ATM,CDC6,CDK1,CDK5RAP3,HUS1B,NAE1,SYF2,TOPBP1 |
| GO_PROTEIN_REFOLDING | 1.4e-05 | 1.6e-04 | 1930 | 39 | 9 | DNAJA2,HSPA14,HSPA6,HSPA8,HSPA9,PDCL,PPIF,PPIG,ST13 |
| GO_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY | 1.4e-05 | 1.6e-04 | 1930 | 39 | 9 | AXIN1,CNOT2,CNOT9,MED1,PAK1,PHB2,STRN3,UFL1,YAP1 |
| GO_TRNA_METHYLATION | 1.4e-05 | 1.6e-04 | 1930 | 39 | 9 | ALKBH8,HSD17B10,NSUN3,THUMPD2,TRMT1,TRMT10A,TRMT13,TYW3,WDR4 |
| GO_VESICLE_BUDDING_FROM_MEMBRANE | 1.4e-05 | 1.6e-04 | 1930 | 106 | 15 | AP3B1,CNIH1,CUL3,DNM2,KLHL21,PEF1,PPP6R1,RAB1A,SAR1A,SEC24B,SEC24C,TMED2,TRAPPC10,VAPA,VPS4A |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_VACUOLE | 1.5e-05 | 1.7e-04 | 1930 | 49 | 10 | AP3B1,HGS,HSPA8,SMURF1,SNX16,VAMP7,VPS37A,VPS4A,VTI1A,WASH3P |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 1.5e-05 | 1.7e-04 | 1930 | 627 | 47 | ATP5F1B,ATP5MG,ATP5PB,BAAT,CDADC1,CTPS1,CYC1,DCK,DCTD,ENTPD7,FOXK2,GMPPB,GMPS,GSK3A,GSR,HINT1,HKDC1,MBD4,MTHFD1,NAPRT,NAXD,NME6,NT5C3A,NT5C3B,NUDT15,NUDT4,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PAPSS2,PFKFB3,PPCDC,RAE1,RAN,REXO2,RNASEH2B,RRM1,SLC22A13,SLC4A1,STOML2,TGDS,TSTA3,UGDH,UNG |
| GO_REGULATION_OF_ATPASE_ACTIVITY | 1.5e-05 | 1.7e-04 | 1930 | 82 | 13 | AHSA2P,DNAJA1,DNAJA2,DNAJB1,DNAJB6,DNAJC9,GTF2H2,HNRNPU,HSCB,NCAPH,PPIF,SIRT1,TSC1 |
| GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 1.5e-05 | 1.7e-04 | 1930 | 297 | 28 | AIDA,AXIN1,CUL1,DAXX,DNAJA1,DVL3,EDN1,FBXW11,GFRAL,ITCH,KAT7,LYN,MAP2K7,MAP4K4,MAPK8,NCOR1,NFKB1,PAK1,PDCD10,TAB2,TNIP2,TRAF2,TRAF4,UBB,UBC,ZEB2,ZNF622,ZNF675 |
| GO_REGULATION_OF_DNA_REPLICATION | 1.6e-05 | 1.8e-04 | 1930 | 107 | 15 | ATF1,BRCA2,CCNA2,CDC6,CDK1,CDK2,CDT1,CHTF18,FAF1,MCIDAS,NUCKS1,OBI1,RBBP6,STOML2,WAPL |
| GO_REGULATION_OF_PHOSPHATASE_ACTIVITY | 1.6e-05 | 1.8e-04 | 1930 | 175 | 20 | ANKLE2,BAG4,CD2BP2,CDK5RAP3,ELL,MASTL,PCDH11X,PPP1R15A,PPP1R2,PPP1R26,PPP1R27,PPP1R37,PPP2R1B,PPP2R5D,PPP2R5E,PPP4R2,PPP6R1,RBM26,SET,TSC1 |
| GO_CELL_DEATH_IN_RESPONSE_TO_OXIDATIVE_STRESS | 1.7e-05 | 1.9e-04 | 1930 | 95 | 14 | ATF4,FBXO7,MELK,NFE2L2,NONO,OXR1,PAWR,PDCD10,PML,SIRT1,SLC7A11,SOD1,TSC1,ZNF622 |
| GO_G2_DNA_DAMAGE_CHECKPOINT | 1.7e-05 | 2.0e-04 | 1930 | 31 | 8 | ATM,BABAM1,CDK1,CDK5RAP3,CHEK1,DTL,SYF2,UIMC1 |
| GO_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 1.7e-05 | 2.0e-04 | 1930 | 31 | 8 | BRD4,CDK12,ELL,GTF2F1,HNRNPU,NELFA,PAF1,SUPT6H |
| GO_EPITHELIUM_DEVELOPMENT | 1.8e-05 | 2.0e-04 | 1930 | 1296 | 81 | ACER1,AKR1C1,AP2B1,ATM,BRCA2,C2CD3,CASP3,CDK1,CLASP2,CLTC,CREB1,CTSL,DVL3,EDN1,ELF5,FEM1B,FOXC1,FOXJ2,FRZB,GNA13,GRSF1,GSK3A,HNRNPH3,HOXA11,IQGAP3,KDM6A,KDM6B,KLF4,KRT16,LIN7C,MAFG,MCIDAS,MED1,MTHFD1,NOTCH1,PAK1,PDCD10,PHB2,PLK4,PML,PSMA1,PSMA2,PSMA3,PSMA7,PSMB2,PSMB5,PSMB6,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC6,PSMD1,PSMD12,PSMD2,PSMD6,PSMD8,PSME2,RAP2C,RBBP6,RBM15,RPS7,SEC24B,SFN,SIX4,SLC7A11,SMAD4,SMURF1,SOD1,SPINK5,TBR1,TBX3,TMED2,TSC1,VDAC1,WNT9B,YAP1,ZEB1,ZEB2,ZNRF3 |
| GO_HISTONE_DEUBIQUITINATION | 1.8e-05 | 2.0e-04 | 1930 | 23 | 7 | BAP1,SART3,UIMC1,USP16,USP21,USP3,USP7 |
| GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DAMAGE_RECOGNITION | 1.8e-05 | 2.0e-04 | 1930 | 23 | 7 | COPS2,COPS3,COPS7B,CUL4A,DDB1,UBB,UBC |
| GO_REGULATION_OF_CYTOPLASMIC_MRNA_PROCESSING_BODY_ASSEMBLY | 1.8e-05 | 2.1e-04 | 1930 | 10 | 5 | ATXN2L,CNOT2,CNOT6,CNOT6L,PATL2 |
| GO_FORMATION_OF_CYTOPLASMIC_TRANSLATION_INITIATION_COMPLEX | 1.9e-05 | 2.1e-04 | 1930 | 16 | 6 | EIF3E,EIF3F,EIF3G,EIF3H,EIF3L,EIF5 |
| GO_NEGATIVE_REGULATION_OF_B_CELL_PROLIFERATION | 1.9e-05 | 2.1e-04 | 1930 | 16 | 6 | ATM,BTK,CASP3,LYN,PAWR,RC3H1 |
| GO_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | 1.9e-05 | 2.1e-04 | 1930 | 16 | 6 | AKAP8L,CPSF6,NUP153,RBM26,RBM27,SUPT6H |
| GO_SNORNA_METABOLIC_PROCESS | 1.9e-05 | 2.1e-04 | 1930 | 16 | 6 | DKC1,EXOSC10,EXOSC3,EXOSC4,EXOSC5,TENT4A |
| GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 2.0e-05 | 2.3e-04 | 1930 | 223 | 23 | BAG3,BCL2L2,BID,BLOC1S2,CASP3,DAXX,FAF1,FEM1B,GFRAL,GSK3A,HIPK1,HMGB2,PAK2,PARP2,PEA15,PHIP,PML,PPP2R1B,TCF7L2,TNFRSF10A,TRAF2,YAP1,ZC3HC1 |
| GO_FEMALE_GAMETE_GENERATION | 2.1e-05 | 2.3e-04 | 1930 | 136 | 17 | AFP,ATM,BRCA2,CCNB1,DIAPH2,DMC1,HSF1,KMT2B,MASTL,MCMDC2,MSH4,NCAPH,NCAPH2,SIRT1,TOP2A,UBB,YTHDF2 |
| GO_PEPTIDYL_SERINE_MODIFICATION | 2.1e-05 | 2.4e-04 | 1930 | 319 | 29 | ARAF,ATM,AURKB,AXIN1,BAG4,CCNB1,CDK1,CDK2,CLK1,CNOT9,CSNK1G1,CSNK2A2,DYRK2,GGNBP2,GSK3A,HIPK1,MAPK8,MASTL,PAK1,PAK2,PARP2,PDCD10,PWP1,RICTOR,RPS6KA5,SMG1,TERF2IP,TLK2,TNKS |
| GO_TRANSLESION_SYNTHESIS | 2.1e-05 | 2.4e-04 | 1930 | 41 | 9 | DTL,NPLOC4,POLK,RCHY1,RFC1,RPA2,UBB,UBC,UFD1 |
| GO_COPII_COATED_VESICLE_BUDDING | 2.2e-05 | 2.4e-04 | 1930 | 73 | 12 | CNIH1,CUL3,KLHL21,PEF1,PPP6R1,RAB1A,SAR1A,SEC24B,SEC24C,TMED2,TRAPPC10,VAPA |
| GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION | 2.2e-05 | 2.5e-04 | 1930 | 32 | 8 | ATM,BANK1,BTK,CASP3,LYN,PAWR,RC3H1,THOC1 |
| GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING | 2.2e-05 | 2.5e-04 | 1930 | 32 | 8 | CCNB1,CPEB1,DAZAP1,HSF1,NUDT21,PAF1,RBMX,SNW1 |
| GO_MITOCHONDRIAL_TRANSLATION | 2.3e-05 | 2.6e-04 | 1930 | 137 | 17 | ALKBH1,MRPL15,MRPL37,MRPL9,MRPS15,MRPS2,MRPS30,MRPS35,MRPS36,MTERF4,MTIF2,MTRF1L,NGRN,NSUN3,QRSL1,RPUSD4,WARS2 |
| GO_CHROMATIN_ORGANIZATION_INVOLVED_IN_REGULATION_OF_TRANSCRIPTION | 2.4e-05 | 2.7e-04 | 1930 | 124 | 16 | ATAD2,BAZ2A,CHEK1,DOT1L,EZH1,FAM172BP,H1-4,H4-16,HAT1,KMT2B,MECP2,MIER1,MSL3,RIF1,SETDB1,SIRT1 |
| GO_GENE_SILENCING | 2.4e-05 | 2.7e-04 | 1930 | 530 | 41 | AGO2,ATAD2,BAZ2A,CDK2,CELF1,CNOT10,CNOT2,CNOT3,CNOT6,CNOT6L,CNOT9,DOT1L,EZH1,FAM172BP,FMR1,FXR1,H1-4,H4-16,HAT1,KMT2B,MECP2,MIER1,MSL3,NCOR1,NUP153,NUP205,NUP42,NUP43,NUP50,NUP62,PABPC1,PUM1,PUM2,RAE1,RAN,RIF1,SETDB1,SIRT1,SNIP1,SRRT,ZC3H7A |
| GO_MEIOTIC_CHROMOSOME_SEPARATION | 2.4e-05 | 2.7e-04 | 1930 | 24 | 7 | ESPL1,FANCM,MSH4,MUS81,NCAPH,NCAPH2,TOP2A |
| GO_OXIDATION_REDUCTION_PROCESS | 2.4e-05 | 2.7e-04 | 1930 | 1005 | 66 | ACO2,ADIPOR1,AIFM2,AKR1C1,ALDH2,ALKBH1,ALKBH3,ALKBH8,BID,CBR3,CCNB1,CDK1,COA6,COX5A,CS,CTBP2,CYB5B,CYC1,DUS3L,DYRK2,ECI1,ECSIT,EGLN2,ERO1B,FOXK2,GFER,GFOD2,GLRX3,GLUD1,GSK3A,GSR,HSD17B10,HSPBAP1,IDH3B,JMJD6,KDM2A,KDM6A,KDM6B,KIAA1191,MECP2,MRPS36,MTFR2,MTHFD1,NDUFA10,NDUFA9,NDUFC2-KCTD14,NDUFS3,NDUFS7,NDUFS8,OGFOD1,OXR1,PPP1R2,PYROXD1,QSOX2,RDH16,RPIA,RRM1,SLC25A25,SOD1,SORD,TET3,TSTA3,TXNL1,UGDH,UQCRC2,UQCRH |
| GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 2.4e-05 | 2.6e-04 | 1930 | 180 | 20 | BID,COA8,FAF1,GSK3A,MAPK8,PAK2,PEA15,PLAGL2,PML,PPIF,PPP2R1B,PPP3CC,PPP3R1,RPS7,SFN,SIRT1,SOD1,TFDP2,TRAF2,UBB |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 2.5e-05 | 2.7e-04 | 1930 | 1026 | 67 | ATM,AXIN1,BAG4,BANK1,BID,BRD4,CASP10,CDK1,CDK5RAP3,CGAS,CHERP,DAXX,DDX1,DDX60,DVL3,EDN1,EEF1E1,FGF22,GFRAL,GPR89A,GSK3A,HIC1,HINT1,IQGAP3,KLB,LYN,MAP2K7,MAP4K4,MIER1,NOTCH1,NUP62,PAK1,PDCD10,PEA15,PHB2,PLAGL2,PPM1A,PTPN11,PUM1,PUM2,RC3H1,REL,RICTOR,RNF31,RPS7,SIRT1,SLC38A9,SOD1,STK19,TAB2,TCF7L2,TELO2,TERF2IP,TICAM1,TNFRSF10A,TNIP2,TRAF2,TRAF4,TRAF5,UBB,UBC,UBE2I,UBE3A,VAPA,ZEB2,ZFP91,ZNF622 |
| GO_PROTEIN_POLYMERIZATION | 2.5e-05 | 2.7e-04 | 1930 | 273 | 26 | ABITRAM,ACTR3,BAG4,BAIAP2L1,BIN1,CAMSAP1,CKAP5,CLASP2,DIAPH3,DRG1,FER,HDGFL3,MECP2,MTPN,NCKAP1,NDEL1,PAK1,RICTOR,SLAIN2,TWF1,UBE2C,UBE2K,VDAC2,WASH3P,WASH6P,WASHC1 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 2.5e-05 | 2.8e-04 | 1930 | 928 | 62 | ABL2,ATF1,BIN1,CDK1,CDK5RAP3,CLCF1,CREB1,DENND5A,DMRTA2,DNM2,DVL3,FBXO7,FMR1,GNRH1,GSK3A,HMGB2,IFRD1,ISL2,ITSN2,KLF4,LRRTM2,LYN,MAPK6,MED1,MTMR2,NAP1L1,NDEL1,NEPRO,NFE2L2,NOTCH1,PAK1,PARD3,PCM1,PLAA,PQBP1,PRTG,RAB21,RNF10,RNF6,RUFY3,SEC24B,SF3A2,SIX4,SMURF1,SNW1,SPART,SRPX2,SRRT,SYT1,TBR1,TCF3,TSC1,TWF1,UBE3A,UFL1,VAMP7,VPS35,YAP1,YTHDF2,ZEB1,ZEB2,ZNF335 |
| GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY | 2.6e-05 | 2.8e-04 | 1930 | 52 | 10 | BTK,CD226,CLCF1,EXOSC3,NSD2,RIF1,SHLD1,SHLD2,SUPT6H,THOC1 |
| GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ENDOPLASMIC_RETICULUM | 2.6e-05 | 2.8e-04 | 1930 | 86 | 13 | ARCN1,BNIP1,ERGIC2,ERGIC3,KIF18A,KIF2C,RAB1A,RACGAP1,RER1,SCYL1,STX18,TMED2,UVRAG |
| GO_POSITIVE_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEGREGATION | 2.8e-05 | 3.1e-04 | 1930 | 17 | 6 | CDT1,CUL3,ESPL1,HNRNPU,NSMCE2,SLF1 |
| GO_PSEUDOURIDINE_SYNTHESIS | 2.8e-05 | 3.1e-04 | 1930 | 17 | 6 | DKC1,GAR1,NAF1,PUS1,PUS7,RPUSD4 |
| GO_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE | 2.8e-05 | 3.1e-04 | 1930 | 33 | 8 | ATF4,DAXX,HNRNPA1,HSF1,PPIF,RNF4,SRRT,ZFAND2A |
| GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION | 2.9e-05 | 3.2e-04 | 1930 | 75 | 12 | CPSF2,CPSF7,FIP1L1,GTF2H2,LSM11,NUDT21,PABPN1,PAPOLA,SCAF4,SCAF8,SLBP,SNRPB |
| GO_VESICLE_TARGETING_TO_FROM_OR_WITHIN_GOLGI | 2.9e-05 | 3.2e-04 | 1930 | 75 | 12 | CNIH1,CUL3,GOSR1,KLHL21,PEF1,PPP6R1,RAB1A,SAR1A,SEC24B,SEC24C,TMED2,TRAPPC10 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 3.0e-05 | 3.2e-04 | 1930 | 213 | 22 | AP1G1,BTK,C12orf4,CD226,CLCF1,DDX1,DDX60,EXOSC3,FER,IL18RAP,LYN,MICB,NFKBID,NSD2,PUM1,PUM2,RIF1,SHLD1,SHLD2,TICAM1,TRAF2,VAMP7 |
| GO_REGULATION_OF_PROTEIN_MONOUBIQUITINATION | 3.1e-05 | 3.4e-04 | 1930 | 6 | 4 | FANCM,PEF1,UBB,WDR48 |
| GO_POSITIVE_REGULATION_OF_MRNA_3_END_PROCESSING | 3.2e-05 | 3.5e-04 | 1930 | 11 | 5 | CCNB1,CPEB1,HSF1,NUDT21,PAF1 |
| GO_POSITIVE_REGULATION_OF_RNA_POLYMERASE_II_TRANSCRIPTIONAL_PREINITIATION_COMPLEX_ASSEMBLY | 3.2e-05 | 3.5e-04 | 1930 | 11 | 5 | CREB1,PSMC2,PSMC3,PSMC4,PSMC6 |
| GO_POSTTRANSLATIONAL_PROTEIN_TARGETING_TO_ENDOPLASMIC_RETICULUM_MEMBRANE | 3.2e-05 | 3.5e-04 | 1930 | 11 | 5 | CHMP4B,GET3,SEC61A2,SEC62,SEC63 |
| GO_CELLULAR_RESPONSE_TO_LIGHT_STIMULUS | 3.3e-05 | 3.5e-04 | 1930 | 127 | 16 | AIPL1,ATF4,AURKB,CDC25A,CHEK1,CREBBP,DDB1,FMR1,GNB1,GRK7,POLK,RRH,SDE2,SIRT1,USP47,YY1 |
| GO_EMBRYONIC_MORPHOGENESIS | 3.3e-05 | 3.5e-04 | 1930 | 592 | 44 | C2CD3,CASP3,CLASP2,CREBBP,CUL3,DNAJB6,DVL3,EDN1,ELF5,FOXC1,FRZB,GRSF1,HIPK1,HOXA11,HOXA9,HOXC11,HOXC9,KDM6A,KDM6B,KLF4,MED1,MTHFD1,NOTCH1,PAF1,POFUT2,RPS7,SEC24B,SIX4,SMAD4,SOD1,SP3,SUPT20H,SYF2,TBR1,TBX3,TMED2,TSC1,UGDH,WNT9B,YAP1,YTHDF2,ZEB1,ZEB2,ZNF568 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 3.3e-05 | 3.5e-04 | 1930 | 88 | 13 | CDK5RAP3,CSNK2A2,DERL2,MARCHF7,PDCL3,PML,RPS7,SENP1,TLK2,USP14,USP7,VPS35,WAC |
| GO_REGULATION_OF_CIRCADIAN_RHYTHM | 3.4e-05 | 3.7e-04 | 1930 | 114 | 15 | CDK1,CREB1,DDB1,FBXL3,FBXW11,KDM2A,MAPK8,NONO,PER3,PML,RBM4B,SIK1,TOP2A,UBE3A,USP7 |
| GO_RESPONSE_TO_ACID_CHEMICAL | 3.5e-05 | 3.8e-04 | 1930 | 345 | 30 | ABCA1,ABL2,ADNP2,AKAP8,AKR1C1,ATF2,ATM,CAPN2,CASP3,CCNB1,CPEB1,CREB1,EDN1,GDAP2,GNB1,GNRH1,HSF1,KLF4,LANCL2,LYN,MICB,PHB2,SLC38A9,SNW1,UFL1,WNT9B,YAP1,YES1,YY1,ZEB1 |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 3.5e-05 | 3.8e-04 | 1930 | 725 | 51 | ACTR3,ADIPOR1,AP2B1,APH1A,ATP6V0A2,ATP6V1G1,ATP6V1H,BAIAP2L1,CASP3,CEP57,CNOT9,FAM83B,FER,FGF22,FOXC1,FRS3,GFRAL,GIGYF1,GSK3A,GTF2F1,HGS,HNRNPA1,HNRNPH1,KLB,LRIT3,LYN,NCKAP1,NDEL1,NUCKS1,NUP62,PAK1,PAK2,PHIP,PTPN11,RAB14,RNF126,RPS6KA5,SH2B1,SH3KBP1,SHCBP1,SIRT1,SNX5,STAM,TIAL1,TMEM108,TSC1,TYRO3,VAV2,WASF2,YES1,ZFAND5 |
| GO_NCRNA_CATABOLIC_PROCESS | 3.6e-05 | 3.8e-04 | 1930 | 34 | 8 | DIS3,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,RBM7,ZCCHC8 |
| GO_PROTEIN_K63_LINKED_DEUBIQUITINATION | 3.6e-05 | 3.8e-04 | 1930 | 34 | 8 | ABRAXAS2,ATXN3,BABAM1,DESI2,OTUD4,OTUD7B,UIMC1,USP16 |
| GO_REGULATION_OF_ISOTYPE_SWITCHING | 3.6e-05 | 3.8e-04 | 1930 | 34 | 8 | CLCF1,EXOSC3,NSD2,RIF1,SHLD1,SHLD2,SUPT6H,THOC1 |
| GO_NEURON_DIFFERENTIATION | 3.7e-05 | 4.0e-04 | 1930 | 1365 | 83 | ABITRAM,ABL2,ADNP2,ALKBH1,ATF1,ATF4,BIN1,BLOC1S2,C12orf57,CAMSAP1,CASP3,CDK5RAP3,COPS2,CREB1,DENND5A,DMRTA2,DNM2,DVL3,FBXO7,FMR1,GALR2,GSK3A,HDGFL3,HIPK1,IFRD1,ISL2,ITSN2,KLF4,LAMA2,LYN,MAP4K4,MAPK6,MECP2,MED1,MTCH1,MTMR2,MTPN,NCKAP1,NDEL1,NEPRO,NFE2L2,NGRN,NOTCH1,NRL,PAK1,PAK2,PARD3,PBX3,PLAA,PQBP1,PTPN11,RAB21,RAB35,RNF6,RPS6KA5,RUFY3,SEC24B,SF3A2,SH3KBP1,SMAD4,SMURF1,SOD1,SPART,SPINK5,STRN,SYT1,TBR1,TCF3,TDP2,TMEM108,TSC1,TWF1,UBA6,UBB,UBE3A,USP21,VAMP7,VAPA,WEE1,WNT9B,ZEB1,ZEB2,ZNF335 |
| GO_CELLULAR_PROCESS_INVOLVED_IN_REPRODUCTION_IN_MULTICELLULAR_ORGANISM | 3.9e-05 | 4.2e-04 | 1930 | 347 | 30 | ATM,BRCA2,CCNB1,CCNB1IP1,CELF1,CEP57,CFAP157,DIAPH2,DMC1,FANCG,FOXC1,HMGB2,HSF1,ICA1L,KIF18A,KMT2B,MASTL,MCMDC2,NCAPH,NCAPH2,ODF2,SLC26A8,SPDYA,SRPK1,TIAL1,TMEM119,TOP2A,TTC26,UBB,YTHDF2 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 3.9e-05 | 4.1e-04 | 1930 | 709 | 50 | ADIPOR1,ATF4,ATP6V0A2,ATP6V1G1,ATP6V1H,BAIAP2L1,BCL2L2,CAPN10,CAPN2,CASP3,CASP7,CCNA2,CDC6,CDK2,CGAS,CHMP5,CPEB1,CREB1,DAXX,DDX11,DNM2,EDN1,FER,FMR1,GNB1,GSK3A,HSF1,KLF4,LYN,NDEL1,NFE2L2,NFKB1,NSG1,NUCKS1,OR56A4,PAK1,PHIP,PQBP1,PTPN11,RAD51,RANGAP1,RIOK3,SIRT1,SLC25A33,SLC38A9,SOD1,TRAF2,TSC1,VPS35,ZEB1 |
| GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS | 3.9e-05 | 4.1e-04 | 1930 | 248 | 24 | AXIN1,CNOT2,CNOT9,DAXX,DDX54,DNAJA1,EDN1,EGLN2,HNRNPU,KAT5,MED1,NCOR1,NR2C2,PAK1,PHB2,RAN,RNF4,RNF6,SIRT1,STRN3,UBE2I,UBE3A,UFL1,YAP1 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 3.9e-05 | 4.2e-04 | 1930 | 469 | 37 | AIDA,ANKLE2,C3orf33,CACTIN,CASP3,CCNB1,CDK5RAP3,CHORDC1,DBNDD2,DNAJA1,FBXO7,FGFR1OP,GGNBP2,HNRNPU,IBTK,IPO7,IRAK3,ITCH,KLF4,LEMD2,LYN,MBIP,NCOR1,NUP62,PAK2,PARD3,PARP14,PPIF,PPP2R5D,PRKRIP1,PWP1,SFN,SIRT1,SMAD4,TERF2IP,WASHC1,ZNF675 |
| GO_CLATHRIN_COAT_ASSEMBLY | 4.1e-05 | 4.3e-04 | 1930 | 18 | 6 | AP2B1,CLINT1,CLTA,CLTB,CLTC,NSG1 |
| GO_DOSAGE_COMPENSATION | 4.1e-05 | 4.3e-04 | 1930 | 18 | 6 | EXOSC10,HNRNPU,LRIF1,PCGF5,RBM15,RLIM |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 4.1e-05 | 4.3e-04 | 1930 | 18 | 6 | BRD4,CDK12,ELL,GTF2F1,PAF1,SUPT6H |
| GO_PROTEIN_AUTOPHOSPHORYLATION | 4.1e-05 | 4.3e-04 | 1930 | 233 | 23 | ATM,AURKB,BTK,CDK12,CLK1,CLK3,FER,GRK7,IRAK3,LYN,MELK,MYLK2,NEK2,PAK1,PAK2,PPP2R5D,PPP2R5E,RAP2C,SIK1,SMG1,STK10,TYRO3,YES1 |
| GO_MUSCLE_STRUCTURE_DEVELOPMENT | 4.2e-05 | 4.4e-04 | 1930 | 673 | 48 | BIN1,BNIP2,BTBD1,CAPN2,CASP3,CCNB1,CCNT2,CDK1,COL6A3,COPS2,CREB1,DMRTA2,EDN1,FLNC,FOXC1,FRG1,FXR1,GSK3A,HINFP,HNRNPU,IFRD1,KDM6B,LAMA2,LEMD2,MECP2,MED1,MED28,MTPN,MYLK2,NOTCH1,PAK1,PARP2,POPDC2,SIK1,SIRT1,SIX4,SMAD4,SOX15,SUPT6H,TBX3,TCF3,TCF7L2,TEAD4,TMEM119,TSC1,YAP1,YY1,ZEB1 |
| GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 4.3e-05 | 4.5e-04 | 1930 | 750 | 52 | ABCA1,ADIPOR1,ANP32B,CDK12,CUL4A,DENND5A,DPF2,ELF5,FBXO7,FOXJ2,FRZB,GNRH1,GSK3A,H4-16,HNRNPU,HOXA9,HSPA9,IFRD1,IQCB1,ISL2,LYN,MECP2,MED1,MED28,N4BP2L2,NEPRO,NFE2L2,NFKBID,NOTCH1,PAF1,PAK1,PCM1,PRTG,RBM15,RC3H1,RCC2,RNF10,RNF6,RUFY3,SINHCAF,SIRT1,SIX4,SMAD4,SPART,TBX3,TMEM119,TSC1,UBE3A,YAP1,YY1,ZEB1,ZNF675 |
| GO_RESPONSE_TO_PEPTIDE | 4.3e-05 | 4.5e-04 | 1930 | 525 | 40 | ADIPOR1,ATP6V0A2,ATP6V1G1,ATP6V1H,BAIAP2L1,BCL2L2,CAPN10,CCNA2,CDC6,CHMP5,CPEB1,CREB1,CYC1,DDX11,EDN1,EIF2B4,FER,GNRH1,GSK3A,HNRNPL,HSF1,KAT7,KLF4,LYN,NDEL1,NFE2L2,NFKB1,NOTCH1,NUCKS1,PAK1,PHIP,PTPN11,RANGAP1,RBBP4,RNF40,SIRT1,SLC25A33,SRSF4,TSC1,UCP3 |
| GO_MATURATION_OF_5_8S_RRNA | 4.4e-05 | 4.5e-04 | 1930 | 26 | 7 | C1D,EXOSC10,EXOSC3,EXOSC4,EXOSC9,NOL9,PES1 |
| GO_NEGATIVE_REGULATION_OF_RNA_SPLICING | 4.4e-05 | 4.5e-04 | 1930 | 26 | 7 | HNRNPK,HNRNPL,RBM10,RBM42,RBMX,RNPS1,SRSF4 |
| GO_REGULATION_OF_TELOMERE_CAPPING | 4.4e-05 | 4.5e-04 | 1930 | 26 | 7 | ATM,AURKB,MAP2K7,NEK2,NEK7,TNKS,USP7 |
| GO_RRNA_MODIFICATION | 4.5e-05 | 4.7e-04 | 1930 | 35 | 8 | DKC1,GAR1,MRM3,MTERF4,NAF1,NSUN3,THUMPD1,ZCCHC4 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 4.6e-05 | 4.8e-04 | 1930 | 1047 | 67 | ABCA1,ADIPOR1,ANP32B,ATF2,BCL2L12,BRCA2,CDK12,CLASP2,CUL4A,DENND5A,DPF2,ELF5,FBXO7,FOXC1,FOXJ2,FRZB,GNRH1,GSK3A,H4-16,HGS,HNRNPU,HOXA9,HSPA9,IFRD1,IQCB1,ISL2,KLF4,LYN,MECP2,MED1,MED28,MTMR2,N4BP2L2,NEPRO,NFE2L2,NFKBID,NOTCH1,PAF1,PAK1,PCM1,PDCD10,PHB2,PML,PRTG,RBM15,RC3H1,RCC2,RNF10,RNF6,RUFY3,SINHCAF,SIRT1,SIX4,SMAD4,SOX15,SPART,SPINK5,TBX3,THOC1,TMEM119,TSC1,UBE3A,WNT9B,YAP1,YY1,ZEB1,ZNF675 |
| GO_SNRNA_METABOLIC_PROCESS | 4.7e-05 | 4.9e-04 | 1930 | 45 | 9 | DKC1,EXOSC10,EXOSC3,EXOSC4,EXOSC5,EXOSC9,INTS7,RBM7,ZCCHC8 |
| GO_DEVELOPMENTAL_GROWTH | 4.8e-05 | 5.0e-04 | 1930 | 677 | 48 | ALKBH1,ANKRD11,ATM,BRCA2,CCNB1,CDK1,COL6A3,COPS2,CREB1,DNM2,EDN1,FOXC1,GINS4,GSK3A,HOXA11,HSF1,IFRD1,ITSN2,KDM6A,MATN1,MED1,MTPN,NDEL1,NOTCH1,PAK1,PARP2,PLAA,PTPN11,RAB21,RBBP6,RNF6,RUFY3,SBDS,SIX4,SLC25A25,SMAD4,SMURF1,SOD1,SOX15,SPART,SYT1,TMED2,TMEM108,UBE3A,WDR48,YAP1,YY1,ZEB2 |
| GO_POSITIVE_REGULATION_OF_MEMBRANE_PERMEABILITY | 4.8e-05 | 5.0e-04 | 1930 | 67 | 11 | ATF2,BID,BLOC1S2,GSK3A,MAPK8,PPIF,PPP3CC,PPP3R1,SFN,SLC25A5,TFDP2 |
| GO_RESPONSE_TO_HYDROGEN_PEROXIDE | 4.8e-05 | 5.0e-04 | 1930 | 145 | 17 | APTX,CAPN2,CASP3,CDK1,HSF1,IL18RAP,KDM6B,KLF4,KPNA4,NFE2L2,PAWR,PDCD10,PPIF,PPP2CB,SIRT1,SOD1,UBE3A |
Num: 11 (Pathways: 700 DK: 14)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (14) | CDK19, DSTYK, HIPK3, LRRK1, MAP3K10, MARK4, NEK11, PIP4K2C, PIP5K1C, RPS6KC1, SBK3, SRPK3, STK38L, TTBK2 |
| Light Kinase (32) | AAK1, ABR, ACVR1, BRD2, CAMK2D, CSNK1D, DGKD, EIF2AK3, FRK, GSK3B, HK1, ILK, INSR, JAK1, LATS2, MAP2K2, MAP3K8, MAPK1, MAPKAPK2, MST1R, MYLK3, MYLK4, NRBP1, NUAK1, PEAK1, PI4K2A, PINK1, SIK3, TAOK3, TGFBR1, TRPM7, ULK1 |
| Non-kinase Count | 1183 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_EXOCYTOSIS | 0.0e+00 | 0.0e+00 | 1229 | 900 | 113 | A1BG,ABR,APBA2,APLP2,APP,ARL8A,ATP11A,ATP13A2,ATP6AP1,ATP6AP2,ATP6V1D,CAP1,CAPN1,CD109,CD63,CDA,CHI3L1,CHMP2A,CHP1,CMTM6,CPNE3,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYSTM1,DMTN,DNAJC3,DNASE1L1,DSP,DYNC1H1,EEF2,EXOC1,EXOC3,EXOC4,EXOC6B,FCER1G,FRK,FTH1,FTL,GAA,GALNS,GMFG,GNAI2,GNS,GRN,GSK3B,HEBP2,HGF,HMOX1,HRG,HYAL3,IDH1,IGF2R,IQGAP1,ITGAV,LAMP2,LAMTOR3,LGALS3,MAGED2,MANBA,MAPK1,MICAL1,MOSPD2,NEU1,NSF,PGM1,PIP5K1C,PLEKHO2,PRCP,PRKN,PROS1,PSAP,PSEN1,RAB11FIP5,RAB31,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RHOA,RHOG,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLC15A4,SLC2A5,SNAP23,SRP14,STING1,STX3,STXBP2,STXBP5,SYNGR3,SYT15,TIMP2,TMBIM1,TOLLIP,TOM1,TSPAN14,VAT1,VNN1,VPS11,WASHC3,YPEL5 |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 1229 | 1680 | 155 | A1BG,AACS,ABR,ANXA4,APBA2,APLP2,APP,AQP9,ARL8A,ATP11A,ATP13A2,ATP6AP1,ATP6AP2,ATP6V1D,CAP1,CAPN1,CD109,CD63,CDA,CHI3L1,CHMP2A,CHP1,CMTM6,COPG1,CPNE3,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYP51A1,CYSTM1,DMTN,DNAJC3,DNASE1L1,DSP,DYNC1H1,DYSF,EEF2,ERP29,EXOC1,EXOC3,EXOC4,EXOC6B,FBLN5,FCER1G,FRK,FRMD4A,FRMD8,FTH1,FTL,FURIN,GAA,GALNS,GALR1,GLUL,GMFG,GNAI2,GNAS,GNS,GRN,GSK3B,HEBP2,HGF,HK1,HMGCR,HMOX1,HRG,HYAL3,IDH1,IGF2R,IL17RA,IQGAP1,ITGAV,ITPR2,KDM5B,LAMP2,LAMTOR3,LGALS3,LRP1,MAGED2,MANBA,MAPK1,MDK,MICAL1,MOSPD2,MPC2,NCOA1,NCOR2,NEU1,NLRP10,NOTCH2,NSF,PAX8,PGM1,PINK1,PIP5K1C,PLA2R1,PLEKHO2,PRCP,PRKN,PROS1,PSAP,PSEN1,RAB11FIP5,RAB31,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RCN3,RHBDF1,RHOA,RHOG,RHOT1,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLC15A4,SLC22A4,SLC26A6,SLC2A5,SLC38A2,SNAP23,SPTBN1,SRP14,STAT5B,STING1,STX3,STXBP2,STXBP5,SYNGR3,SYT15,TIMP2,TMBIM1,TNFRSF14,TNFSF4,TOLLIP,TOM1,TRAF6,TRPM4,TRPV4,TSPAN14,VAT1,VNN1,VPS11,WASHC3,YPEL5 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1741 | 157 | ACOT8,ACOX1,AKAP13,APOD,APP,APPBP2,ARHGAP21,ARL8A,ARL8B,ATG13,ATP13A2,ATXN1,BBS12,BCAS3,BTBD8,CAPZB,CD63,CD81,CDC42,CEMIP,CERT1,CHM,CHMP1B,CHMP2A,CHP1,CLN3,CLTCL1,CMTM6,COPG1,CSNK1D,CTSA,DAB2,DCTN2,DENND10,DENND3,DMTN,DST,DYNC1H1,EHHADH,EPS15,ERC1,ERP29,EXOC4,FCER1G,GABARAP,GDI1,GOLGA2,GOLGB1,GSK3B,HEATR5B,HMOX1,HTATIP2,IDH1,IFT27,INPP5K,INSIG1,KCNE1,KIF3C,KIFAP3,LAMP2,LCA5,LEPROT,LYST,MAP1B,MAP2,MAP2K2,MAPK1,MIEF2,MON2,MSN,MT-ATP6,MT-ATP8,MTM1,MVB12B,MYO1C,NCOA4,NPEPPS,NRBP1,NSF,NUCB1,OS9,OSBPL2,PAOX,PCSK9,PEX6,PHYH,PINK1,PKIG,PMM1,PRKN,PROS1,PRR5L,PSEN1,PTTG1IP,RAB23,RAB31,RAB32,RAB43,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RABGAP1,RABGAP1L,RFTN1,RGP1,RHOT1,RILP,RTN2,S100A13,SCARB2,SDCBP,SH3GLB1,SMG6,SNAP23,SNX33,SNX6,SNX8,SNX9,SPAG9,SPTBN1,SQSTM1,SRP14,STARD4,STX3,STX7,STX8,STXBP2,TBC1D12,TBC1D17,TBC1D22A,TBC1D23,TBC1D3B,TBC1D9B,TMED4,TMEM50A,TMEM50B,TOM1,TRAPPC6A,TRAPPC8,TSC2,UBXN6,USP6,VIPAS39,VPS11,VPS26C,WASHC2C,WASL,WDR19,WIPI1,YIPF5,YWHAZ,ZDHHC1,ZDHHC2,ZDHHC7,ZFYVE16 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 1930 | 160 | ACOT8,ACOX1,APOD,APPBP2,ARMCX3,ATG13,ATP13A2,ATP6V1D,BBS12,BCAS3,CD63,CD81,CDC42,CEMIP,CHM,CHP1,CLTCL1,COPG1,CORO1B,CSNK1D,CTNNA1,CTNNB1,CTSA,CYLD,DAB2,DBN1,DCTN2,DMTN,EHHADH,EIF2AK3,EPS15,ERP29,EXOC1,EXOC3,EXOC4,FBLN5,FCER1G,FCHO2,FGF13,GABARAP,GBP2,GDI1,GLIS2,GLUL,GOLGB1,GSK3B,HK1,IDH1,IFT27,INPP5K,INSIG1,IQGAP1,ITGB1,KCNE1,KIF3C,KIFAP3,LAMP2,LAMTOR3,LCA5,LEPROT,LGALS3,LRP1,LRSAM1,MACF1,MADCAM1,MAP2,MAPK1,MARK4,MEAK7,MIEF2,MOAP1,MSN,MYADM,MYO1C,NCOA4,NPEPPS,NSF,NUCB1,NUMB,OPHN1,OPTN,OS9,PAOX,PEX6,PHYH,PINK1,PKIG,PMM1,PRKN,PRR5L,PSEN1,PTTG1IP,RAB11FIP5,RAB23,RAB31,RAB32,RAB43,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RABGAP1,RABGAP1L,RFTN1,RHOG,RHOQ,RRAGC,RTN2,RTN4,SCARB2,SDCBP,SH3GLB1,SKP1,SMAD7,SMG6,SNX33,SNX6,SNX8,SNX9,SORBS1,SPTBN1,SQSTM1,SRP14,STX3,STX7,STX8,TAPT1,TBC1D12,TBC1D17,TBC1D22A,TBC1D3B,TBC1D9B,TINF2,TMBIM1,TMED4,TMEM150A,TMEM59,TMEM88,TOLLIP,TOM1,TP53INP2,TRAPPC8,TSC2,TSPAN14,TTBK2,USP6,VIPAS39,VPS11,VPS26C,WASHC2C,WASL,WDR19,WDR45,WIPI1,YWHAZ,ZDHHC1,ZDHHC2,ZDHHC7,ZFYVE16 |
| GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 0.0e+00 | 0.0e+00 | 1229 | 549 | 83 | A1BG,ABR,ADAM17,ARL8A,ATP11A,ATP6AP2,ATP6V1D,CAP1,CAPN1,CD63,CDA,CHI3L1,CMTM6,CPNE3,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYSTM1,DNAJC3,DNASE1,DNASE1L1,DSP,DYNC1H1,EEF2,FCER1G,FRK,FTH1,FTL,GAA,GALNS,GMFG,GNS,GRN,HEBP2,HMOX1,IDH1,IGF2R,IQGAP1,ITGAV,LAMP2,LAMTOR3,LGALS3,MANBA,MAPK1,MOSPD2,NEU1,PGM1,PLEKHO2,PRCP,PSAP,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RHOA,RHOG,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLC15A4,SLC2A5,SNAP23,SPON2,SRP14,STING1,STXBP2,TIMP2,TMBIM1,TOLLIP,TOM1,TSPAN14,VAT1,VNN1,YPEL5 |
| GO_IMMUNE_EFFECTOR_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1267 | 125 | A1BG,ABI1,ABR,ACTG1,ADAM17,APLF,APP,ARL8A,ARPC3,ATP11A,ATP6AP2,ATP6V1D,BAIAP2,C1S,CAP1,CAPN1,CD63,CD81,CDA,CDC42,CHI3L1,CMTM6,CPNE3,CRK,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYSTM1,DNAJC3,DNASE1,DNASE1L1,DSP,DYNC1H1,DYSF,EEF2,ERCC6,EXOC1,FCER1G,FCGRT,FRK,FTH1,FTL,GAA,GALNS,GMFG,GNS,GRN,HEBP2,HK1,HMOX1,IDH1,IFIT3,IGF2R,IGHV3-74,IQGAP1,IRF9,ITGAV,LAMP2,LAMTOR3,LGALS3,LRP1,LYST,MANBA,MAPK1,MDK,MICA,MOSPD2,MYO1C,NDFIP1,NEU1,NOTCH2,PGM1,PLEKHO2,PRCP,PROS1,PSAP,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RAPGEF1,RFTN1,RHOA,RHOG,S100A11,S100A13,SDCBP,SERINC3,SERINC5,SERPINB1,SERPINB6,SHFL,SIRPA,SIRPB1,SLAMF6,SLC15A4,SLC2A5,SMAD7,SNAP23,SPON2,SRP14,STAT2,STAT5B,STING1,STX7,STXBP2,SWAP70,TIMP2,TMBIM1,TNFRSF14,TNFSF4,TOLLIP,TOM1,TRAF6,TRPM4,TSPAN14,VAT1,VNN1,WASL,YPEL5 |
| GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1229 | 710 | 93 | A1BG,ABR,APLF,APP,ARL8A,ATP11A,ATP6AP2,ATP6V1D,CAP1,CAPN1,CD63,CD81,CDA,CHI3L1,CMTM6,CPNE3,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYSTM1,DNAJC3,DNASE1,DNASE1L1,DSP,DYNC1H1,DYSF,EEF2,FCER1G,FRK,FTH1,FTL,GAA,GALNS,GMFG,GNS,GRN,HEBP2,HMOX1,IDH1,IGF2R,IQGAP1,ITGAV,LAMP2,LAMTOR3,LGALS3,LRP1,MANBA,MAPK1,MDK,MOSPD2,NDFIP1,NEU1,NOTCH2,PGM1,PLEKHO2,PRCP,PSAP,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RHOA,RHOG,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLAMF6,SLC15A4,SLC2A5,SMAD7,SNAP23,SRP14,STING1,STXBP2,SWAP70,TIMP2,TMBIM1,TNFSF4,TOLLIP,TOM1,TSPAN14,VAT1,VNN1,YPEL5 |
| GO_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 1229 | 1442 | 132 | A1BG,ABR,ACTG1,ADAM17,APLF,APP,ARL8A,ATP11A,ATP6AP2,ATP6V1D,CAP1,CAPN1,CD151,CD276,CD63,CD81,CDA,CDC42,CHI3L1,CMTM6,CPNE3,CST3,CSTB,CTNNB1,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYLD,CYSTM1,DGKD,DMTN,DNAJC3,DNASE1,DNASE1L1,DSP,DUSP3,DYNC1H1,DYSF,EEF2,EFNB3,FCER1G,FNIP1,FRK,FTH1,FTL,FZD8,GAA,GALNS,GMFG,GNAS,GNS,GPNMB,GRN,HDAC5,HEBP2,HMOX1,HRG,IDH1,IGBP1,IGF2R,IGHV3-74,IL17RA,ILK,IQGAP1,ITGAV,ITGB1,ITPR2,KLF6,LAMP2,LAMTOR3,LGALS3,LMBR1L,LRP1,LRRC8A,MANBA,MAP3K8,MAPK1,MDK,MICA,MOSPD2,MSN,MYL12A,NDFIP1,NEU1,NOS3,NOTCH2,PGM1,PJA2,PLEKHO2,PRCP,PSAP,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RHOA,RHOG,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLAMF6,SLC15A4,SLC2A5,SMAD7,SNAP23,SRP14,STAT5B,STING1,STXBP2,SWAP70,TGFBR1,TIMP2,TMBIM1,TNFRSF14,TNFSF4,TOLLIP,TOM1,TRAF6,TSPAN14,TWSG1,VAT1,VNN1,YPEL5,YWHAZ,ZMIZ1 |
| GO_LEUKOCYTE_MEDIATED_IMMUNITY | 0.0e+00 | 0.0e+00 | 1229 | 872 | 101 | A1BG,ABR,ADAM17,APLF,ARL8A,ATP11A,ATP6AP2,ATP6V1D,C1S,CAP1,CAPN1,CD63,CD81,CDA,CHI3L1,CMTM6,CPNE3,CRK,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYSTM1,DNAJC3,DNASE1,DNASE1L1,DSP,DYNC1H1,EEF2,FCER1G,FCGRT,FRK,FTH1,FTL,GAA,GALNS,GMFG,GNS,GRN,HEBP2,HMOX1,IDH1,IGF2R,IGHV3-74,IQGAP1,ITGAV,LAMP2,LAMTOR3,LGALS3,LYST,MANBA,MAPK1,MICA,MOSPD2,NDFIP1,NEU1,PGM1,PLEKHO2,PRCP,PSAP,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RFTN1,RHOA,RHOG,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLAMF6,SLC15A4,SLC2A5,SMAD7,SNAP23,SPON2,SRP14,STAT5B,STING1,STX7,STXBP2,SWAP70,TIMP2,TMBIM1,TNFSF4,TOLLIP,TOM1,TRAF6,TRPM4,TSPAN14,VAT1,VNN1,YPEL5 |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 0.0e+00 | 0.0e+00 | 1229 | 650 | 86 | A1BG,ABR,APP,ARL8A,ATP11A,ATP6AP2,ATP6V1D,CAP1,CAPN1,CD63,CDA,CHI3L1,CMTM6,CPNE3,CST3,CSTB,CTSA,CTSB,CTSD,CYB5R3,CYFIP1,CYSTM1,DNAJC3,DNASE1,DNASE1L1,DSP,DYNC1H1,DYSF,EEF2,FCER1G,FRK,FTH1,FTL,GAA,GALNS,GMFG,GNS,GRN,HEBP2,HMOX1,IDH1,IGF2R,IQGAP1,ITGAV,LAMP2,LAMTOR3,LGALS3,MANBA,MAPK1,MOSPD2,NEU1,NOTCH2,PGM1,PJA2,PLEKHO2,PRCP,PSAP,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RHOA,RHOG,S100A11,S100A13,SDCBP,SERPINB1,SERPINB6,SIRPA,SIRPB1,SLC15A4,SLC2A5,SNAP23,SRP14,STING1,STXBP2,TIMP2,TMBIM1,TOLLIP,TOM1,TRAF6,TSPAN14,VAT1,VNN1,YPEL5 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1301 | 118 | ACAN,ACAT1,ALDH6A1,APOC1,ATP13A2,ATP2B4,BLVRB,CACUL1,CAMLG,CD81,CDA,CEMIP,CHP1,CLN8,CPQ,CSNK1D,CSPG4,CST3,CTBS,CTNNB1,CTSA,CTSB,CTSD,CTSF,CUL7,CYLD,CYP51A1,DAB2,DAB2IP,DACT1,DCN,DENND3,DNAJB2,DNAJC3,DYSF,EFNA1,FAP,FBXL12,FBXL2,FURIN,GABARAPL2,GALNS,GLUL,GNS,GSK3B,HMGCR,HMOX1,HYAL3,KCTD10,KCTD21,LAMP2,LRP1,LRRC29,LRSAM1,MANBA,MSN,MTM1,MVB12B,NDFIP1,NEU1,NOS3,NPEPPS,NRDC,NSF,NT5C2,OPHN1,OS9,PAOX,PCSK9,PINK1,PLA2G15,PRKN,PSAP,PSEN1,PTTG1IP,RAB7A,RCN3,RGP1,RHBDF1,RILP,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SAT2,SCPEP1,SDC2,SDCBP,SGPL1,SHARPIN,SIRT2,SKP1,SMAD7,SMPD1,SNX33,SNX9,SPSB3,SQSTM1,TIMP2,TOLLIP,TP53INP2,TPP1,TRPC4AP,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,UPB1,USP11,USP6,USP9Y,VPS11,ZER1 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 1863 | 144 | ABR,AKAP13,AKR1C3,APP,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ATP2B4,ATP6AP1,ATP6AP2,AUTS2,CAMK2D,CASTOR2,CASTOR3,CAVIN3,CD81,CDC42,CDC42SE1,CDC42SE2,CHI3L1,CHP1,CRK,CSPG4,CTNNB1,CXCR4,CYLD,CYTH1,CYTH2,DAB2IP,DACT1,DCN,DSTYK,DUSP3,EFNA1,EIF2AK3,EPS8L1,EPS8L2,ERCC6,ERP29,FBXL2,FNIP1,FZD8,GDI1,GMIP,GNAI2,GPNMB,GRINA,GSK3B,HGF,HIPK3,HMGCR,HMOX1,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,ITGB1,KANK1,KCTD10,LAMTOR3,LBH,LITAF,LMCD1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MIB2,MST1R,MTM1,MYADM,NDFIP1,NFAT5,NOTCH2,NUAK1,OPHN1,OPTN,PHLDA3,PIK3IP1,PINK1,PIP4K2C,PIP5K1C,PJA2,PLA2R1,PPEF2,PPM1N,PPP2R5B,PRKN,PRR5L,PRXL2C,PSAP,PSD4,PSEN1,PTPRR,PTTG1IP,RAPGEF1,RCN3,RHOA,RHOC,RHOG,RHOQ,RHOT1,RRAGC,RRAS,RTN4,S100A13,SDCBP,SERINC3,SHARPIN,SHOC2,SIK3,SIRPA,SKIL,SMPD1,SPAG9,SQSTM1,TANK,TAOK3,TBC1D7,TGFBR1,TIAM2,TIMP2,TMED4,TMEM127,TP53INP1,TRAF6,TRPV4,TSC2,UBE2B,UBR2,VNN1,WDR59,ZDHHC17 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 1721 | 136 | AACS,ABHD2,ACAT1,ACSL1,ACVR1,ADAM17,ADAMTSL2,ADCY2,AKAP13,AKAP9,AKR1C3,APP,AQP9,ARNT2,ARPC3,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CALCOCO1,CASTOR2,CASTOR3,CD109,CD81,COL6A1,CORO1B,CREBRF,CRK,CTNNA1,CTNNB1,CTSB,CYFIP1,DAB2,DAB2IP,DHCR24,DMTN,DSTYK,DUSP3,EEF2,FAM89B,FBXO32,FCER1G,FIBIN,FNDC4,FOXO4,FURIN,GALNT3,GLG1,GNAI2,GNAS,GSK3B,HADHA,HCN3,HDAC5,HMGCS1,IDH1,ILK,INPP5K,INSR,IQGAP1,ITGB1,ITPR2,KANK1,KCNE1,KDM5B,KLF11,KLF2,LAMTOR3,LATS2,LBH,LEPROT,LPIN1,LPIN2,LRP1,LTBP3,MAP1B,MAPK1,MDK,MEAK7,MSN,MYO1C,NCOA1,NCOA4,NCOR2,NOS3,NOTCH2,NQO1,NR4A1,NRIP1,PAX8,PCSK9,PLPP1,PRCP,PRKN,PSEN1,RAB31,RAB8B,RAPGEF1,RHOA,RHOQ,RNF14,RRAGC,SCX,SDCBP,SHOC2,SIRT2,SKIL,SLC26A6,SMAD7,SMAD9,SNX6,SORBS1,STAT2,STAT5B,TGFBR1,TIMP2,TMEM38A,TNFSF4,TRIP4,TRPM4,TRPV4,TSC2,TWSG1,UBR2,UCN2,USP9Y,VASN,VIM,WBP2,WDTC1,ZFHX3,ZFYVE16 |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 1335 | 117 | ABI1,ABR,ABRAXAS1,ACTG1,AKAP13,AKAP9,ARAP1,ARHGAP10,ARPC3,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CAP1,CAPG,CAPZB,CAVIN3,CCDC6,CCSER2,CDC42,CDC42EP2,CDK2AP2,CEP126,CEP295NL,CETN2,CFAP410,CHMP1B,CHMP2A,CHP1,CLIC4,CLN8,CORO1B,CORO2B,CRK,CSNK1D,CTNNB1,CUL7,CYFIP1,CYLD,CYTH2,DBN1,DCTN2,DMTN,DSP,DST,DSTN,DYNC1H1,EHBP1L1,ERMN,FGF13,GABARAP,GMFG,GOLGA2,GOLGA8N,GSK3B,HRG,ILK,INPP5K,ITGB1,KANK1,KIZ,KLHL24,LIMCH1,LRCH3,LRP1,MACF1,MAP1B,MAP2,MAP7D3,MAPK1,MARK4,MDK,MICAL1,MSN,MTM1,MYADM,MYLK3,MYO1C,NCKAP5L,NEDD9,NOTCH2,OPHN1,PALLD,PARD3B,PDLIM7,PIP5K1C,PLXNA3,PRKN,RHOA,RHOC,RHOG,RHOQ,RP1L1,RSPH9,SDCBP,SIK3,SNX9,SORBS1,SPEF1,SPTBN1,SVIL,SWAP70,SYNM,TGFBR1,TPGS1,TRIM54,TRPM7,TRPV4,TTBK2,TTLL3,UBE2B,VIM,WASHC2C,WASHC3,WASL,WDPCP |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1894 | 142 | AACS,AAK1,ABR,AHNAK,AKAP9,ANXA4,APBA2,APOC1,APOD,APP,ATG13,ATP13A2,ATP2B4,ATP6AP1,BCAS3,BEST1,BTBD9,CAMK2D,CAPN1,CD151,CD63,CD81,CDC42,CEMIP,CHMP2A,CHP1,CLIC4,CLTCL1,CREBL2,CTNNB1,CXCR4,CYFIP1,CYP51A1,DAB2,DENND10,DMTN,DYNC1H1,DYSF,ERP29,EXOC1,FCER1G,FRMD4A,FRMD8,GALR1,GDI1,GLUL,GNAI2,GNAS,GSK3B,HCN3,HK1,HMGCR,HMOX1,HYAL3,IL17RA,INPP5K,INSIG1,INSR,ITGAV,ITPR2,KCNE1,KCNK6,KDM5B,KLHL24,LEPROT,LGALS3,LRP1,LRSAM1,MAP1B,MAP2,MAP2K2,MAPK1,MDK,MFGE8,MICAL1,MIEF2,MPC2,MSN,MYO1C,NDFIP1,NLRP10,NOS3,NPEPPS,NSF,NUCB1,NUMB,OPHN1,OS9,PAX8,PCSK9,PINK1,PKIG,PLA2R1,PRKN,PRR5L,PSEN1,RAB11FIP5,RAB23,RAB31,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RAPGEF1,RHBDF1,RHOA,RHOQ,RHOT1,RTN2,RUBCN,SARAF,SDCBP,SERPINB1,SESTD1,SH3GLB1,SIRPA,SIRPB1,SLC26A6,SLC31A2,SNX33,SORBS1,SPTBN1,STXBP2,STXBP5,SYNGR3,SYT15,TMEM102,TMEM38A,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4,TSC2,USP6,VPS11,WASL,YIPF5,YWHAZ,ZFYVE16,ZNF205 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 1267 | 113 | AKAP13,AKAP9,ARAP1,ARPC3,ATG13,ATP13A2,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CALCOCO2,CAMK2D,CAPG,CAPZB,CDC42,CDC42EP2,CDK2AP2,CEP295NL,CHMP1B,CHMP2A,CLIC4,CORO1B,CORO2B,CRK,CTCFL,CTNNB1,CUL7,CYFIP1,CYLD,DBN1,DCN,DMTN,DSTN,DYNC1H1,FGF13,FNIP1,GMFG,GRN,GSK3B,HGF,HRG,ILK,INPP5K,INSIG1,INSR,JDP2,KANK1,KDM5A,LEPROT,LIMCH1,LRP1,LRSAM1,MAP1B,MAP2,MAP2K2,MAPK1,MARK4,MDK,MIEF2,MOAP1,MSN,MTM1,MTMR3,MYADM,MYLK3,MYO1C,NOTCH2,NPEPPS,OPTN,PDE4DIP,PINK1,PIP4K2C,PLXNA3,PRKN,PTPRD,RAB7A,RHOA,RHOC,RHOG,RHOQ,RHOT1,RUBCN,SCARB2,SDCBP,SH3GLB1,SIRT2,SMG6,SNX9,SPEF1,SPTBN1,SQSTM1,STAT2,SWAP70,TAPT1,TBC1D12,TBC1D7,TGFBR1,TINF2,TMEM102,TRIM54,TRPV4,TSC2,TTBK2,UBE2B,ULK1,VAT1,VPS11,WASHC2C,WASL,WBP2,YWHAZ,ZNF205 |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 0.0e+00 | 0.0e+00 | 1229 | 499 | 70 | AMBRA1,ATG13,ATG2B,ATP13A2,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALCOCO2,CAPN1,CAPNS1,CHMP2A,CLN3,CTSA,DCN,DEPP1,EXOC1,EXOC4,FBXL2,FUNDC2,GABARAP,GABARAPL2,GOLGA2,GSK3B,HGF,HMOX1,KDM4A,LAMP2,LAMTOR3,LRSAM1,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MCOLN1,MTM1,MTMR3,OPTN,PINK1,PIP4K2C,PLEKHM1,PRKN,PSAP,PSEN1,RAB23,RAB7A,RRAGC,RUBCN,SH3GLB1,SIRT2,SNX14,SNX6,SPTLC1,SQSTM1,STING1,TBC1D12,TBC1D17,TMEM150A,TMEM59,TOLLIP,TP53INP1,TP53INP2,TRAPPC8,TRIM21,TSC2,UBXN6,ULK1,VPS11,WDR45,WIPI1,ZFYVE1 |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 987 | 98 | AMBRA1,APOC1,APP,ARNT,ATG13,ATP13A2,ATP2B4,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALCOCO2,CAMLG,CAPN1,CAPNS1,CD81,CSNK1D,CST3,CTSA,CYP51A1,DAB2,DAB2IP,DACT1,DCN,DEPP1,DNAJB2,DYSF,EFNA1,EXOC1,EXOC4,FAP,FBXL2,FURIN,GABARAPL2,GOLGA2,GSK3B,HGF,HMGCR,HMOX1,IDH1,INSR,ITGB1,KDM4A,LAMTOR3,LRP1,LRSAM1,MAPKAPK2,MSN,MTM1,MTMR3,NDFIP1,NRDC,NSF,OPHN1,OPTN,OS9,PCSK9,PINK1,PIP4K2C,PNPLA2,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTTG1IP,RAB7A,RGP1,RHBDF1,RILP,RNF14,RRAGC,RUBCN,SCARB2,SDCBP,SH3GLB1,SIRT2,SLC2A6,SMAD7,SNX33,SNX6,SNX9,SPTLC1,STING1,TBC1D12,TIMP2,TMEM150A,TMEM59,TP53INP1,TP53INP2,TRIM21,TSC2,UBXN1,ULK1,VIM,VPS11,YWHAZ,ZER1 |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 1229 | 1425 | 119 | ACAN,ACTG1,ACVR1,ADAM17,APOD,APP,ARHGAP5,ARHGDIG,ASS1,BAIAP2,BCAS3,CD151,CD164,CD276,CD63,CD81,CDC42,CDH9,CERCAM,COL13A1,COL6A1,COL6A2,CORO2B,CRK,CTNNA1,CTNNB1,CXCR4,CYLD,CYTH1,DMTN,DSP,DST,DUSP3,DYSF,EFNA1,EFNB3,FAP,FBLIM1,FBLN5,GNAS,GPNMB,GSK3B,HRG,ILK,IQGAP1,ITGA1,ITGA7,ITGAV,ITGB1,KANK1,KIFAP3,LAMC1,LGALS3,LIMCH1,LPP,LRP1,MACF1,MADCAM1,MAP3K8,MDK,MEGF9,MFGE8,MSN,MYADM,MYL12A,NDFIP1,NEDD9,NFAT5,NID1,NRCAM,NUAK1,PALLD,PARD3B,PCDHB10,PCDHB13,PCDHB14,PCDHB15,PCDHB9,PCDHGA1,PCDHGA10,PCDHGA11,PCDHGA5,PCDHGA6,PCDHGA7,PCDHGA9,PCDHGB2,PCDHGB7,PCDHGC4,PEAK1,PIP5K1C,PLXNA3,PSEN1,PTPRD,RAPGEF1,RHOA,S100A11,SGCE,SIRPA,SIRPB1,SMAD7,SORBS1,SPARCL1,SPON2,STAT5B,STX3,SWAP70,THBS3,TMEM102,TNFRSF14,TNFSF4,TRAF6,TRPM7,TRPV4,TWSG1,VNN1,WASHC2C,WDPCP,ZFHX3,ZMIZ1 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 831 | 88 | AMBRA1,APOC1,APP,ARNT,ATG13,ATP13A2,ATP2B4,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALCOCO2,CAMLG,CAPN1,CAPNS1,CD81,CSNK1D,CST3,CTSA,DAB2,DAB2IP,DACT1,DCN,DEPP1,DNAJB2,EFNA1,EXOC1,EXOC4,FBXL2,FURIN,GABARAPL2,GOLGA2,GSK3B,HGF,HMOX1,IDH1,INSR,KDM4A,LAMTOR3,LRP1,LRSAM1,MAPKAPK2,MSN,MTM1,MTMR3,NRDC,OPHN1,OPTN,OS9,PCSK9,PINK1,PIP4K2C,PNPLA2,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTTG1IP,RGP1,RHBDF1,RNF14,RRAGC,RUBCN,SCARB2,SDCBP,SH3GLB1,SIRT2,SMAD7,SNX33,SNX6,SNX9,SPTLC1,STING1,TBC1D12,TIMP2,TMEM150A,TMEM59,TP53INP1,TP53INP2,TRIM21,TSC2,UBXN1,ULK1,VIM,VPS11,YWHAZ,ZER1 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 1545 | 123 | ABI1,AKAP9,APOD,APP,ARAP1,ARHGEF6,ATP6V1D,AUTS2,AVIL,B3GNT2,BAIAP2,BBS12,BCAS3,BTBD8,C15orf62,CAPZB,CDC42,CDC42EP2,CEP126,CETN2,CFAP410,CORO1B,CRK,CSNK1D,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,CYLD,DAB2IP,DBN1,DCTN2,DMTN,DOK4,DYNC1H1,EFNA1,EFNB3,EPS8L1,EPS8L2,ERCC6,ERMN,FAM161B,FGF13,FRYL,GDI1,GRN,GSK3B,HGF,HRG,IFT27,ILK,INPP5K,INSR,IQGAP1,ITGA1,ITGB1,KANK1,KIF3C,KIFAP3,LCA5,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,MARK4,MDK,NRCAM,NUMB,NYAP1,OFD1,OPHN1,PALLD,PDLIM7,PLEKHM1,PLEKHO1,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAB23,RAB8B,RAPGEF1,RETREG3,RHOA,RHOG,RHOQ,RP1L1,RSPH9,RTN4,SCARB2,SDC2,SDCBP,SEMA4B,SEMA6C,SKIL,SPTBN1,STX3,TAPT1,TBC1D23,TBC1D7,TGFBR1,TOP2B,TPGS1,TRPV4,TTBK2,TTLL3,UBE2B,UBE4B,ULK1,UST,VIM,WASL,WDPCP,WDR19,ZSWIM4,ZSWIM8 |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1229 | 1051 | 99 | ABI1,ACTG1,ACVR1,ADAM17,ADAMTSL2,APOD,APP,ARAP1,ARID5B,ARNT,ARPC3,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CAMLG,CD109,CD63,CDC42,CPNE3,CRK,CSPG4,CTNNB1,CYFIP1,DAB2,DAB2IP,DCN,DGKD,DSTYK,DUSP3,EFNA1,EFNB3,EIF2AK3,EPS15,ESM1,FAM89B,FOXO4,FRK,FURIN,GALNT3,GLG1,GNAI2,GSK3B,HGF,HRG,IGF2R,IGFBP6,ILK,INPP5K,INSR,IQGAP1,ITGA1,ITGAV,KANK1,LEPROT,LRP1,LTBP3,MAPK1,MAPKAPK2,MPZL1,MST1,MST1R,MVB12B,MYO1C,NCF2,NOTCH2,PPP2R5B,PSEN1,PTPRD,PTPRR,RAB7A,RAPGEF1,RHBDF1,RHOA,RHOQ,RTN4,SCX,SDC2,SDCBP,SGPL1,SHOC2,SIRT2,SKIL,SMAD7,SMAD9,SNX6,SORBS1,SPTBN1,STAT5B,TGFBR1,TSC2,TWSG1,USP9Y,VASN,VIM,WASL,ZFYVE16 |
| GO_MACROAUTOPHAGY | 0.0e+00 | 0.0e+00 | 1229 | 295 | 53 | AMBRA1,ATG13,ATG2B,ATP13A2,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALCOCO2,CAPN1,CAPNS1,CHMP2A,CLN3,DCN,EXOC1,EXOC4,GABARAP,GABARAPL2,HMOX1,LAMP2,LAMTOR3,LRSAM1,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MCOLN1,MTM1,MTMR3,OPTN,PINK1,PIP4K2C,PRKN,PSEN1,RAB23,RAB7A,RRAGC,RUBCN,SH3GLB1,SNX14,SNX6,SPTLC1,SQSTM1,STING1,TBC1D12,TP53INP1,TP53INP2,TRAPPC8,TSC2,UBXN6,ULK1,WDR45,WIPI1,ZFYVE1 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1410 | 116 | ACAN,AGO4,ATP13A2,CACUL1,CAMLG,CAPN1,CD81,CEMIP,CHP1,CLN8,CSNK1D,CSPG4,CST3,CTBS,CTNNB1,CTSA,CTSB,CTSD,CTSF,CUL7,CYLD,CYP51A1,DAB2,DAB2IP,DACT1,DCN,DEDD2,DENND3,DNAJB2,DNAJC3,DNASE1,DNASE1L1,DNASE2,DYSF,EFNA1,FAP,FBXL12,FBXL2,FURIN,GAA,GABARAPL2,GALNS,GNS,GSK3B,HMGCR,HYAL3,KCTD10,KCTD21,LAMP2,LRP1,LRRC29,LRSAM1,MANBA,MAPKAPK2,MSN,MTM1,MVB12B,NDFIP1,NRDC,NSF,OPHN1,OS9,PCSK9,PGM1,PGM2L1,PINK1,PRKN,PRR5L,PSEN1,PTTG1IP,RAB7A,RCN3,RGP1,RHBDF1,RILP,RNASEH2C,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SCPEP1,SDC2,SDCBP,SH3GLB1,SHARPIN,SIRT2,SKP1,SMAD7,SMG6,SNX33,SNX9,SPSB3,SQSTM1,TIMP2,TOLLIP,TP53INP2,TPP1,TRPC4AP,TUT7,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,USP11,USP6,USP9Y,VIM,VPS11,YWHAZ,ZER1,ZHX2 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 1454 | 118 | AACS,ABHD2,ACSL1,ACVR1,ADAM17,ADAMTSL2,ADCY2,AKAP13,AKAP9,AKR1C3,APP,AQP9,ARPC3,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CALCOCO1,CASTOR2,CASTOR3,CD109,COL6A1,CORO1B,CREBRF,CRK,CTNNA1,CTNNB1,CTSB,CYFIP1,DAB2,DAB2IP,DMTN,DSTYK,DUSP3,EEF2,FAM89B,FBXO32,FOXO4,FURIN,GALNT3,GLG1,GNAI2,GNAS,GSK3B,HCN3,HDAC5,HMGCS1,ILK,INPP5K,INSR,IQGAP1,ITPR2,KANK1,KCNE1,KDM5B,KLF11,KLF2,LAMTOR3,LATS2,LBH,LEPROT,LPIN1,LPIN2,LRP1,LTBP3,MAP1B,MAPK1,MSN,MYO1C,NCOA1,NCOA4,NCOR2,NOTCH2,NR4A1,NRIP1,PAX8,PCSK9,PLPP1,PRCP,PRKN,PSEN1,RAB31,RAB8B,RAPGEF1,RHOA,RHOQ,RNF14,RRAGC,SCX,SDCBP,SHOC2,SIRT2,SKIL,SLC26A6,SMAD7,SMAD9,SNX6,SORBS1,STAT5B,TGFBR1,TMEM38A,TNFSF4,TRIP4,TRPM4,TSC2,TWSG1,UBR2,UCN2,USP9Y,VASN,VIM,WBP2,WDTC1,ZFYVE16 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1880 | 137 | ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,APP,ARNT,ATG13,ATP2B4,ATP6AP1,ATP6AP2,AUTS2,CACUL1,CAMK2D,CAMLG,CAVIN3,CCNG1,CCNI,CCNYL2,CD109,CD81,CDC42,CEMIP,CHI3L1,CHP1,CREBL2,CRK,CRTAP,CSNK1D,CSPG4,CTCFL,CTDSP2,CTNNB1,CXCR4,CYLD,DAB2,DAB2IP,DACT1,DMTN,DNAJB2,DNAJC3,DSTYK,DUSP3,DYSF,EFNA1,EIF2AK3,ERCC6,ERP29,FGF13,FNIP1,FZD8,GMFG,GNAI2,GOLGA2,GPNMB,GSK3B,HGF,HIPK3,HMGCR,HRG,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,JDP2,KDM5A,LAMTOR3,LATS2,LBH,LGALS3,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MICAL1,MST1,MST1R,MYADM,NDFIP1,NEDD9,NOTCH2,NUAK1,PINK1,PJA2,PKIG,PPEF2,PPP2R5B,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTPRR,PTTG1IP,RAPGEF1,RHOA,RRAS,SDCBP,SH3BP5,SHOC2,SIRPA,SIRT2,SMAD7,SMPD1,SNX6,SNX9,SPAG9,SQSTM1,STAT2,SWAP70,TANK,TAOK3,TBC1D7,TGFBR1,TIMP2,TINF2,TMEM102,TMEM59,TNFRSF14,TOLLIP,TRAF6,TRIM21,TRPV4,TSC2,TWSG1,UBE2B,UBXN1,WBP2 |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1229 | 1984 | 140 | ABHD2,ABR,ACVR1,ADAM17,APOD,APP,ARID5B,ARPC3,ATP2B4,AUTS2,B3GNT2,BCAS3,CAP1,CD151,CD63,CD81,CDC42,CEMIP,CHMP2A,CLIC4,CORO1B,CPNE3,CRK,CSPG4,CTNNA1,CTNNB1,CXCR4,CYFIP1,DAB2,DAB2IP,DCN,DMTN,DOK4,DST,DUSP3,DYSF,EFNA1,EFNB3,FAM89B,FAP,FCER1G,FGF13,FOXO4,GLG1,GLUL,GNAI2,GPNMB,GRN,HDAC5,HGF,HMOX1,HRG,IGSF10,IL17RA,ILK,INSR,IQGAP1,ITGA1,ITGAV,ITGB1,KANK1,LAMC1,LGALS3,LIMCH1,LRP1,LYST,MACF1,MADCAM1,MAP1B,MAP2K2,MAPK1,MDK,MEAK7,MEGF9,MOSPD2,MSN,MST1,MTUS1,MYADM,MYO1C,NEDD9,NOS3,NR4A1,NRCAM,NRDC,NUMB,OPHN1,PALLD,PC,PDLIM7,PEAK1,PIP5K1C,PLEKHO1,PLPP1,PLXNA3,PRCP,PROS1,PRR5L,PSEN1,PTPRR,RAB7A,RHBDF1,RHOA,RHOC,RHOG,RRAS,RRAS2,RSPH9,RTN4,SDC2,SDCBP,SEMA4B,SEMA6C,SGPL1,SIRPA,SMAD7,SPAG9,SPEF1,SPTBN1,STAT5B,STX3,SWAP70,TGFBR1,TMEM102,TNFRSF14,TOP2B,TP53INP1,TPGS1,TRIM21,TRIM35,TRPM4,TRPV4,TSC2,TTBK2,UBE2B,WASL,WDPCP,WNT5B,ZSWIM4,ZSWIM8 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1229 | 1994 | 140 | AAK1,ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,APP,ARHGEF6,ATG13,ATP13A2,ATP2B4,ATP6AP1,ATP6AP2,CACUL1,CAMK2D,CAVIN3,CCNG1,CCNI,CCNYL2,CD109,CD81,CDC42,CDK19,CEMIP,CHI3L1,CHP1,CPNE3,CREBL2,CRK,CSF2RA,CSNK1D,CSPG4,CTDSP2,CTNNB1,CXCR4,CYLD,DAB2,DAB2IP,DACT1,DMTN,DNAJC3,DSTYK,DUSP3,EFNA1,EIF2AK3,ERC1,ERCC6,ERP29,FGF13,FNIP1,FRK,FZD8,GMFG,GNAI2,GPNMB,GSK3B,HGF,HIPK3,HMGCR,HRG,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,ITGAV,JAK1,LAMTOR3,LATS2,LBH,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MARK4,MICAL1,MST1,MST1R,MYADM,MYLK3,MYLK4,NEDD9,NEK11,NOTCH2,NUAK1,PEAK1,PINK1,PJA2,PKIG,PPEF2,PPP2R5B,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTPRR,RAPGEF1,RASAL2,RHOA,RPS6KC1,RRAS,SBK3,SDCBP,SH3BP5,SIK3,SIRPA,SIRT2,SKP1,SMAD7,SMPD1,SNX6,SNX9,SPAG9,SPTBN1,SQSTM1,SRPK3,STAT2,STK38L,TAOK3,TGFBR1,TIMP2,TMEM102,TNFRSF14,TRAF6,TRPM7,TRPV4,TSC2,TTBK2,TWSG1,UBE2B,ULK1 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1229 | 1698 | 127 | AACS,ABHD2,ABR,ACSL1,ADAM17,ADCY2,ADH5,AKAP9,AKR1C3,APOD,APP,AQP9,ARNT2,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CALCRL,CASTOR2,CASTOR3,CDK19,COL6A1,COL6A2,CRK,CTNNA1,CTNNB1,CYFIP1,DAB2IP,DCN,DMTN,EEF2,ERCC6,FBLN5,FBXO32,FIBIN,FOXO4,GJD3,GLUL,GNAI2,GNAS,GRAMD1A,GSK3B,HADHA,HCN3,HDAC5,HGF,HMGCR,HMGCS1,HMOX1,HSD17B2,IGF2R,INPP5K,INSIG1,INSR,IQGAP1,ITPR2,KANK1,KCNE1,KLF11,KLF2,LAMTOR3,LEPROT,LITAF,LPIN1,LPIN2,LRP1,LY96,MAP1B,MAP1LC3A,MAPK1,MAPKAPK2,MEAK7,MPC2,MSN,MT-ND5,MT-ND6,MYO1C,NCOA1,NCOR2,NOS3,NQO1,NR4A1,NRIP1,OSER1,OTUD5,P2RX6,PCSK9,PINK1,PRDX5,PRKN,PSAP,PSEN1,RAB11FIP5,RAB31,RAB8B,RAPGEF1,RHOA,RHOQ,RRAGC,SCD,SIRPA,SIRT2,SLC26A6,SLC2A5,SMPD1,SNX6,SORBS1,SPON2,STAT2,STAT5B,TGFBR1,TNFSF4,TP53INP1,TRAF6,TRPM4,TRPV4,TSC2,UBR2,VIM,WBP2,WDTC1,WNT5B,ZNF277 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 1037 | 96 | AACS,AAK1,ANXA4,APOD,ARHGDIG,ATG13,ATP13A2,BCAS3,CD81,CDC42,CEMIP,CHP1,CORO2B,CTNNB1,CTSD,CYLD,CYP51A1,DAB2,DBN1,DMTN,EIF2AK3,ERP29,EXOC1,FCER1G,FRMD4A,FRMD8,GDI1,GLIS2,GLUL,GSK3B,HK1,HMGCR,IL17RA,INPP5K,INSIG1,IQGAP1,ITGB1,ITPR2,KCNE1,LEPROT,LGALS3,LRP1,MAP2,MAPK1,MARK4,MDK,MEAK7,MIEF2,MPC2,MSN,MYO1C,NDFIP1,NLRP10,NPEPPS,NUCB1,NUMB,OPHN1,OS9,PINK1,PKIG,PLEKHM2,PRKN,PRR5L,PSEN1,RAB11FIP5,RAB23,RAB9A,RABGAP1L,RHBDF1,RHOG,RHOQ,RTN4,SERPINB1,SH3GLB1,SLC26A4,SNX33,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,SWAP70,TMBIM1,TMEM59,TNFRSF14,TNFSF4,TP53INP2,TRAF6,TRPM4,TRPV4,TTBK2,VPS11,WASL,WDPCP,YWHAZ |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 1141 | 101 | ABI1,ACTG1,AGO4,AKAP13,APP,ARAP1,AUTS2,B3GNT2,BAIAP2,C15orf62,CAP1,CAPZB,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,CDH9,CERT1,CFAP410,CLIC4,COL6A1,COL6A2,CORO1B,CRK,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,DAB2IP,DBN1,DMTN,DOK4,EFNA1,EFNB3,ERMN,FBLIM1,FGF13,FRYL,GDI1,GSK3B,HGF,ILK,IQGAP1,ITGA1,ITGA7,ITGAV,ITGB1,KANK1,KLF2,LAMC1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,MATN3,MDK,MEGF9,MSN,MTM1,MYADM,MYL12B,MYLK3,NEDD9,NRCAM,NUMB,NYAP1,OPHN1,PALLD,PDLIM7,PEAK1,PLEKHO1,PLXNA3,PMP22,PRKN,PSEN1,PTPRD,RHOA,RHOC,RHOG,RHOQ,RP2,RTN4,S100A13,SDC2,SEMA4B,SEMA6C,SKIL,SPTBN1,TOP2B,ULK1,UST,WASHC2C,WASL,WDPCP,WDR19,ZSWIM4,ZSWIM8 |
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1405 | 113 | AACS,ABHD2,ACAT1,ACAT2,ACOT8,ACOX1,ACSL1,ACSS2,ADH5,AKR1C3,ALKBH7,AMBRA1,APOBR,APOC1,APOD,APP,CD81,CDC42,CDIPT,CDS2,CERT1,CHD9,CLN8,CPNE3,CREBL2,CRK,CTSA,CYB5R3,CYP51A1,CYP8B1,DAB2IP,DECR1,DGKD,DHCR24,EBP,EHHADH,ELOVL1,ERG28,ESYT1,ESYT2,FDFT1,FDPS,GK,GPCPD1,HADHA,HADHB,HMGCR,HMGCS1,HSD17B11,HSD17B2,IDH1,IDI1,INPP5K,INSIG1,IP6K1,LACTB,LPIN1,LPIN2,LRP1,LRP10,LSS,MBOAT2,MSMO1,MTM1,MTMR3,NCOA1,NCOR2,NEU1,NSDHL,OSBPL1A,OSBPL2,PC,PCSK9,PHYH,PI4K2A,PIGG,PIK3IP1,PIP4K2C,PIP5K1C,PITPNM1,PLA2G15,PLD3,PLPP1,PNPLA2,PNPLA6,PNPLA7,PSAP,RAB7A,RETSAT,RUBCN,SAMD8,SC5D,SCD,SCPEP1,SDC2,SERINC1,SERINC2,SERINC3,SERINC5,SGPL1,SIRT2,SLC22A4,SMPD1,SOAT1,SORBS1,SPTLC1,STARD4,STAT5B,TIAM2,TMEM150A,TPP1,TXNRD1,WDTC1 |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1229 | 725 | 77 | ABI1,ACTG1,ADAM17,APOD,APP,ARAP1,ARID5B,ARNT,ARPC3,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CAMLG,CD63,CDC42,CPNE3,CRK,CSPG4,CTNNB1,CYFIP1,DAB2IP,DCN,DGKD,DSTYK,DUSP3,EFNA1,EFNB3,EIF2AK3,EPS15,ESM1,FOXO4,FRK,GALNT3,GNAI2,GSK3B,HGF,HRG,IGF2R,IGFBP6,INPP5K,INSR,IQGAP1,ITGA1,ITGAV,KANK1,LEPROT,LRP1,MAPK1,MAPKAPK2,MPZL1,MST1,MST1R,MVB12B,MYO1C,NCF2,PPP2R5B,PSEN1,PTPRR,RAB7A,RAPGEF1,RHBDF1,RHOA,RHOQ,RTN4,SDC2,SDCBP,SGPL1,SHOC2,SIRT2,SNX6,SORBS1,STAT5B,TSC2,WASL |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1229 | 1869 | 131 | AACS,AAK1,ACVR1,ADAM17,AKAP13,AKR1C3,APP,ARAP1,ARNT,ATP6AP1,ATP6AP2,AUTS2,BAIAP2,CALB1,CAVIN3,CD63,CD81,CDC42,CDC42SE2,CHI3L1,CREBRF,CRK,CSNK1D,CSPG4,CTNNA1,CTNNB1,CXCR4,CYFIP1,CYLD,DAB2,DAB2IP,DACT1,DCN,DEDD2,DMTN,DSTYK,EFNA1,EPS15,ERCC6,ERP29,ESM1,EVC,FRAT1,FZD8,GALR1,GLUL,GNAI2,GPNMB,GRIN2D,GSK3B,HGF,HMGCR,HMOX1,ILK,INSR,IQGAP1,ITGA1,ITGB1,KANK1,LAMTOR3,LITAF,LMCD1,LRP1,LRRK1,LY96,MACF1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MIB2,MOAP1,MPC2,MST1R,MYO1C,NDFIP1,NFAT5,NOS3,NOTCH2,NSF,PINK1,PJA2,PLA2R1,PPM1N,PPP2R5B,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,RAB8B,RAPGEF1,RHOA,RHOC,RHOG,RNF146,RRAGC,RTN4,S100A13,SCUBE3,SDCBP,SERINC3,SH3BGRL,SHARPIN,SHOC2,SIK3,SKIL,SORBS1,SPAG9,SQSTM1,STX3,TAOK3,TGFBR1,TIMP2,TMED4,TRAF6,TRPM4,TRPV4,TSHZ3,TSPAN14,TWSG1,UBE2B,WBP2,WDFY1,WDR59,YWHAZ,ZDHHC17,ZMIZ1,ZNF205 |
| GO_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 938 | 88 | ATP13A2,CACUL1,CAMLG,CD81,CLN8,CSNK1D,CST3,CTNNB1,CTSA,CTSB,CTSD,CTSF,CUL7,CYLD,CYP51A1,DAB2,DAB2IP,DACT1,DENND3,DNAJB2,DNAJC3,DYSF,EFNA1,FAP,FBXL12,FBXL2,FURIN,GABARAPL2,GSK3B,HMGCR,KCTD10,KCTD21,LAMP2,LRP1,LRRC29,LRSAM1,MANBA,MSN,MTM1,MVB12B,NDFIP1,NRDC,NSF,OPHN1,OS9,PCSK9,PINK1,PRKN,PSEN1,PTTG1IP,RAB7A,RCN3,RGP1,RHBDF1,RILP,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SCPEP1,SDCBP,SHARPIN,SIRT2,SKP1,SMAD7,SNX33,SNX9,SPSB3,SQSTM1,TIMP2,TOLLIP,TP53INP2,TPP1,TRPC4AP,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,USP11,USP6,USP9Y,VPS11,ZER1 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1823 | 128 | ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,AMBRA1,APOC1,APP,ARNT,ATG13,ATP2B4,ATP6AP1,ATP6AP2,CACUL1,CAVIN3,CCNG1,CCNI,CCNYL2,CD109,CD81,CDA,CDC42,CEMIP,CHI3L1,CHP1,CREBL2,CRK,CSNK1D,CSPG4,CTDSP2,CTNNB1,CXCR4,CYLD,DAB2,DAB2IP,DACT1,DMTN,DNAJC3,DSTYK,DUSP3,EFNA1,EIF2AK3,ERCC6,ERP29,FGF13,FNIP1,FZD8,GMFG,GNAI2,GPNMB,GSK3B,HGF,HIPK3,HMGCR,HRG,IDH1,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,LATS2,LBH,LGALS3,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MICAL1,MST1,MST1R,MTMR3,MYADM,NEDD9,NOS3,NOTCH2,NUAK1,PIK3IP1,PINK1,PJA2,PKIG,PPEF2,PPP2R5B,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTPRR,RAPGEF1,RHOA,RRAS,RUBCN,SDCBP,SH3BP5,SHOC2,SIRPA,SIRT2,SLC2A6,SMAD7,SMG6,SMPD1,SNX6,SNX9,SPAG9,SQSTM1,STAT2,SWAP70,TAOK3,TGFBR1,TIMP2,TMEM102,TNFRSF14,TRAF6,TRPV4,TSC2,TWSG1,UBE2B,ZFYVE1 |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 669 | 73 | ABI1,ACAN,ACTG1,AKAP13,AKAP9,APP,ARAP1,ARPC3,AVIL,BAIAP2,C15orf62,CAP1,CAPG,CAPZB,CDC42,CDC42EP2,CEP126,CHP1,COL11A2,CORO1B,CORO2B,CSNK1D,CST3,CYFIP1,DBN1,DMTN,DSP,DST,DSTN,DYNC1H1,ERMN,FBLN5,FGF13,GMFG,GOLGA2,ILK,INPP5K,ITGB1,KANK1,KLHL24,LIMCH1,MAP1B,MAP2,MAP7D3,MICAL1,MTM1,MYADM,MYLK3,MYO1C,NCKAP5L,NEDD9,PLOD2,PRKN,PSEN1,RHOA,RHOC,RHOG,RHOQ,SCX,SNX9,SORBS1,SPEF1,SPTBN1,SWAP70,TGFBR1,TRIM54,TRPV4,TTBK2,VIM,VIPAS39,WASHC2C,WASHC3,WASL |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1229 | 1781 | 126 | ABI1,ABR,ACSL1,ADAM17,ADCY2,AKAP13,AKAP9,ALS2CL,AMBRA1,APOC1,APP,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ARID5B,ASAP2,ATG13,ATP2B4,BCAS3,CACUL1,CCNYL2,CD81,CDC42,CDC42EP2,CEMIP,CHI3L1,CHM,CHP1,CRK,CSPG4,CTNNB1,CTSA,CTSD,CXCR4,DAB2IP,DACT1,DNAJB2,DSTYK,EFNA1,EIF2AK3,ERC1,ERCC6,ERP29,FANK1,FGF13,FZD8,GABARAPL2,GDI1,GIT2,GMFG,GMIP,GNAI2,GNAS,GOLGA2,GRAMD4,GRN,GSK3B,HDAC5,HGF,ILK,INSR,IQGAP1,ITGA1,ITGB1,LAMTOR3,LGALS3,LRP1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NCF2,NEDD9,NOS3,OPHN1,PINK1,PPP2R5B,PRKN,PSAP,PSEN1,RABGAP1,RABGAP1L,RAPGEF1,RASAL2,RCN3,RGP1,RHOA,RHOC,RHOG,RP2,RPS27L,SAV1,SERINC1,SERINC2,SERINC5,SIRT2,SNX9,SPAG9,STING1,STXBP5,SYNGR3,TANK,TAOK3,TBC1D12,TBC1D17,TBC1D19,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,TGFBR1,TIAM2,TIMP2,TRAF6,TRIM21,TRIM52,TSC2,USP6 |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 1229 | 1758 | 125 | ABHD2,ABR,ACVR1,ADAM17,APOD,APP,ARID5B,ARPC3,ATP2B4,AUTS2,BCAS3,CAP1,CD151,CD63,CD81,CDC42,CEMIP,CLIC4,CORO1B,CPNE3,CRK,CSPG4,CTNNA1,CTNNB1,CXCR4,DAB2,DAB2IP,DCN,DMTN,DST,DUSP3,DYSF,EFNA1,FAM89B,FAP,FCER1G,FGF13,FOXO4,GLG1,GLUL,GNAI2,GPNMB,GRN,HDAC5,HGF,HMOX1,HRG,IGSF10,IL17RA,ILK,INSR,IQGAP1,ITGA1,ITGAV,ITGB1,KANK1,LAMC1,LGALS3,LIMCH1,LRP1,LYST,MACF1,MADCAM1,MAP1B,MAP2K2,MAPK1,MDK,MEAK7,MEGF9,MOSPD2,MSN,MST1,MTUS1,MYADM,MYO1C,NEDD9,NOS3,NR4A1,NRCAM,NRDC,NUMB,OPHN1,PALLD,PEAK1,PIP5K1C,PLEKHO1,PLPP1,PLXNA3,PRCP,PROS1,PRR5L,PSEN1,PTPRR,RHBDF1,RHOA,RHOC,RHOG,RRAS,RRAS2,RSPH9,RTN4,SDC2,SDCBP,SEMA4B,SEMA6C,SGPL1,SIRPA,SMAD7,SPAG9,SPEF1,STAT5B,SWAP70,TGFBR1,TMEM102,TNFRSF14,TOP2B,TP53INP1,TPGS1,TRPM4,TRPV4,TTBK2,UBE2B,WASL,WDPCP,WNT5B |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1935 | 132 | AACS,ACO1,ACOX1,ACSL1,ACTG1,ADAM17,ADCY2,ANXA6,APP,AQP9,ARNT,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BBS12,BTBD9,CALB1,CAMK2D,CEMIP,CERT1,CHP1,CLCN3,CLCN6,CLIC4,CLN3,CLN8,CP,CSMD1,CTNNB1,CXCR4,CYBRD1,CYLD,DCN,DECR1,DEDD2,DMTN,DNAJB2,DNASE2,DYNC1H1,ELOVL1,ERCC6,FCER1G,FOXO4,FTH1,FTL,GAA,GALR1,GNAI2,GNAS,GRIN2D,GRINA,GRN,HECTD4,HK1,HMGCR,HMOX1,INPP5K,INSIG1,INSR,IP6K1,ITGAV,ITPR2,KLF13,KLF2,LAMP2,LCA5,LPIN1,LRP1,LRRC8A,LRRK1,LTBP3,MAPK1,MCOLN1,MCOLN3,MICU1,MPC2,MTM1,NCF2,NCOA4,NDFIP1,NOS3,NQO1,NRDC,PCSK9,PINK1,PLEKHM1,PNPLA2,POLD4,PRCP,PRDX5,PRKN,PSEN1,RAB11FIP5,RAB7A,RCN3,RHOT1,ROGDI,RP1L1,RTN4,SCD,SCX,SKIL,SKP1,SLC12A4,SLC12A6,SLC26A4,SLC26A6,SLC31A2,SLC39A13,SLC4A3,SMAD7,SMARCAL1,SMG6,SOAT1,STAT5B,SWAP70,TINF2,TLCD2,TMEM165,TMEM38A,TP53INP2,TPP1,TRAF6,TRPM4,TRPM7,TRPV4,TXNRD1,WDTC1 |
| GO_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1692 | 121 | ABCC11,ACSL1,AHNAK,AKAP9,ANO10,ANXA6,APOC1,APP,AQP9,ATP10D,ATP11A,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,ATP9A,BEST1,CA14,CALCRL,CAMK2D,CAPN1,CD63,CEMIP,CERT1,CHP1,CHRNB1,CLCN3,CLCN6,CLCN7,CLIC4,CLN3,CLN8,COX6A1,COX6C,CP,CTNNB1,CTNS,CXCR4,DYSF,FCER1G,FGF13,FTH1,FTL,GJD3,GNAI2,GRIN2D,HCN3,HRG,INPP5K,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,LGALS3,LRRC8A,MAGED2,MCOLN1,MCOLN3,MICU1,MPC2,MT-ATP6,MT-ATP8,NCOA1,NDFIP1,NIPA1,NOS3,NSF,OSBPL2,OSTM1,P2RX6,PCSK9,PINK1,PITPNM1,PLA2R1,PRKN,PSAP,PSEN1,REP15,RHOA,SARAF,SCARB2,SESTD1,SLC10A6,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC16A13,SLC17A5,SLC22A15,SLC22A3,SLC22A4,SLC26A11,SLC26A4,SLC26A6,SLC2A6,SLC31A2,SLC37A1,SLC38A2,SLC38A7,SLC39A13,SLC41A2,SLC43A2,SLC4A3,SNAP23,SYT15,TMCO3,TMEM165,TMEM38A,TMEM63B,TRPC4AP,TRPM4,TRPM7,TRPV4,XKR8,XKR9,ZDHHC17 |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 547 | 65 | ADAMTS4,AMBRA1,ATG13,ATG2B,ATP13A2,AVIL,CALCOCO2,CAPG,CAPN1,CAPNS1,CAPZB,CHMP1B,CHMP2A,CLN3,CST3,CTNNB1,DEDD2,DMTN,DNASE2,DSTN,DUSP3,FAP,FGF13,FRAT1,FUNDC2,FURIN,GABARAP,GABARAPL2,GOLGA2,GSK3B,INSR,LAMC1,LAMP2,LPIN1,LRP1,MAP1B,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MCOLN1,MICAL1,NCKAP5L,NSF,OPTN,PINK1,PRKN,RUBCN,SCUBE3,SHARPIN,SHFL,SNX14,SPEF1,SPTBN1,SQSTM1,STING1,SWAP70,TGFBR1,TIMP2,TRIM54,TRPV4,TSC2,TTBK2,WASHC2C,WDR45,WIPI1 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 1429 | 109 | ABI1,ABR,ACSL1,ADAM17,ADCY2,AKAP13,ALS2CL,AMBRA1,APOC1,APP,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ASAP2,ATG13,ATP2B4,BCAS3,CACUL1,CCNYL2,CD81,CDC42,CDC42EP2,CEMIP,CHI3L1,CHM,CRK,CSPG4,CTNNB1,CTSA,CTSD,CXCR4,DAB2IP,DNAJB2,DSTYK,EFNA1,EIF2AK3,ERCC6,ERP29,FGF13,FZD8,GABARAPL2,GDI1,GIT2,GMFG,GMIP,GNAI2,GNAS,GOLGA2,GRAMD4,GRN,GSK3B,HGF,ILK,INSR,IQGAP1,ITGA1,ITGB1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NCF2,NEDD9,NOS3,OPHN1,PINK1,PSAP,PSEN1,RABGAP1,RABGAP1L,RAPGEF1,RASAL2,RCN3,RGP1,RHOA,RHOC,RHOG,RP2,RPS27L,SERINC1,SERINC2,SERINC5,SNX9,SPAG9,STXBP5,TANK,TAOK3,TBC1D12,TBC1D17,TBC1D19,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,TGFBR1,TIAM2,TIMP2,TRAF6,TSC2,USP6 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 0.0e+00 | 1229 | 1107 | 94 | ABHD2,ABR,ACVR1,ADAM17,AKAP9,APOD,APP,ARAP1,BCAS3,CAMK2D,CD151,CD81,CEMIP,CLIC4,CORO1B,CPNE3,CRK,CTNNA1,CXCR4,DAB2,DAB2IP,DCN,DMTN,DSP,DUSP3,DYSF,EFNA1,FAM89B,FGF13,FOXO4,GLUL,GNAI2,GPNMB,GRN,HDAC5,HGF,HMOX1,HRG,IGBP1,IGSF10,ILK,INSR,IQGAP1,ITGAV,ITGB1,KANK1,LGALS3,LIMCH1,LRP1,MACF1,MADCAM1,MAP2,MAP2K2,MAPK1,MDK,MEAK7,MOSPD2,MSN,MST1,MTUS1,MYADM,MYO1C,NEDD9,NOS3,NUMB,PLXNA3,PRCP,PRR5L,PTPRR,RHOA,RHOC,RHOG,RHOT1,RRAS,RRAS2,RTN4,SDCBP,SEMA4B,SEMA6C,SMAD7,SPAG9,SWAP70,TGFBR1,TMEM102,TNFRSF14,TP53INP1,TRPM4,TRPV4,TTBK2,WASL,WDPCP,WNT5B,ZSWIM4,ZSWIM8 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1229 | 1779 | 124 | ABRAXAS1,ACAN,ADAM17,ADAMTS4,ADAMTSL1,ADAMTSL2,APLP2,APP,ATP13A2,ATP6AP2,C1S,CACUL1,CAMLG,CAPN1,CAPNS1,CD109,CLN3,CLN8,CPD,CPQ,CSNK1D,CST3,CSTB,CTNNB1,CTSA,CTSB,CTSD,CTSF,CUL7,CYLD,DAB2,DAB2IP,DHCR24,DNAJB2,DNAJC3,EFNA1,EIF2AK3,FAP,FBXL12,FBXL2,FNIP1,FOXO4,FURIN,GABARAPL2,GLG1,GRAMD4,GRN,GSK3B,HGF,HRG,IGBP1,KCTD10,KCTD21,LACTB,LRP1,LRRC29,MICAL1,MINDY2,MPND,MST1,MTM1,MVB12B,NDFIP1,NPEPPS,NRDC,OPHN1,OS9,OTUD5,PCSK9,PEPD,PIK3IP1,PINK1,PRCP,PRDX5,PRKN,PROS1,PRSS27,PSEN1,RCN3,RHBDF1,RHOA,RHOT1,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,RNPEP,RPS27L,SCPEP1,SDCBP,SERPINB1,SERPINB6,SHARPIN,SIRT2,SKP1,SMAD7,SNX33,SNX9,SPSB3,SQSTM1,TANK,TGFBR1,TIMP2,TMEM59,TMPRSS9,TOLLIP,TP53INP2,TPP1,TRAF6,TRIM21,TRPC4AP,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,USP11,USP6,USP9Y,ZER1 |
| GO_VACUOLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 164 | 37 | AMBRA1,ATG13,ATG2B,ATP13A2,CLN3,CLN8,GAA,GABARAP,GABARAPL2,GRN,HPS1,LRSAM1,LYST,MAN2A1,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MTM1,MTMR3,PINK1,PIP4K2C,PSEN1,RAB23,RAB7A,SCARB2,SH3GLB1,STING1,TBC1D12,TMEM165,TP53INP1,TP53INP2,TPP1,TRAPPC8,ULK1,VPS11,WDR45,WIPI1 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1151 | 95 | ACOT8,ACOX1,APOD,APPBP2,ATG13,ATP13A2,BBS12,BCAS3,CD81,CDC42,CEMIP,CHM,CHP1,CLTCL1,COPG1,CTSA,DMTN,EHHADH,ERP29,EXOC4,GABARAP,GDI1,GSK3B,IDH1,IFT27,INPP5K,INSIG1,KCNE1,KIF3C,KIFAP3,LAMP2,LCA5,LEPROT,MAPK1,MIEF2,MYO1C,NCOA4,NPEPPS,NSF,NUCB1,OS9,PAOX,PEX6,PHYH,PINK1,PKIG,PMM1,PRKN,PRR5L,PSEN1,PTTG1IP,RAB23,RAB31,RAB32,RAB43,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RABGAP1,RABGAP1L,RFTN1,RTN2,SCARB2,SDCBP,SH3GLB1,SMG6,SNX33,SNX6,SNX8,SNX9,SRP14,STX3,STX7,STX8,TBC1D12,TBC1D17,TBC1D22A,TBC1D3B,TBC1D9B,TMED4,TOM1,TRAPPC8,TSC2,USP6,VIPAS39,VPS11,VPS26C,WDR19,YWHAZ,ZDHHC1,ZDHHC2,ZDHHC7,ZFYVE16 |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1229 | 1625 | 116 | ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,AMBRA1,APP,ARNT,ATG13,ATP2B4,ATP6AP1,ATP6AP2,CACUL1,CAVIN3,CCNG1,CCNI,CCNYL2,CD109,CD81,CDC42,CEMIP,CHI3L1,CHP1,CREBL2,CRK,CSNK1D,CSPG4,CTDSP2,CTNNB1,CXCR4,CYLD,DAB2,DAB2IP,DACT1,DMTN,DNAJC3,DSTYK,DUSP3,EFNA1,EIF2AK3,ERCC6,ERP29,FGF13,FNIP1,FZD8,GMFG,GNAI2,GPNMB,HGF,HIPK3,HMGCR,HRG,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,LATS2,LBH,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MICAL1,MST1,MST1R,MYADM,NEDD9,NOTCH2,PIK3IP1,PINK1,PJA2,PKIG,PPEF2,PPP2R5B,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTPRR,RAPGEF1,RHOA,RRAS,RUBCN,SDCBP,SH3BP5,SIRPA,SIRT2,SLC2A6,SMAD7,SMPD1,SNX6,SNX9,SPAG9,SQSTM1,STAT2,TAOK3,TGFBR1,TIMP2,TMEM102,TNFRSF14,TRAF6,TRPV4,TSC2,TWSG1,UBE2B |
| GO_REGULATION_OF_CELL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 491 | 60 | AGO4,ARAP1,BAIAP2,C15orf62,CAPZB,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,CFAP410,CORO1B,CRK,CUL7,CUX1,CXCR4,CYFIP1,DBN1,DMTN,EFNA1,EFNB3,ERMN,FBLIM1,FGF13,GDI1,GSK3B,ILK,ITGA7,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MDK,MSN,MYADM,MYL12B,NEDD9,NRCAM,PLEKHO1,PLXNA3,PRKN,PSEN1,PTPRD,RHOA,RHOC,RHOG,RHOQ,RTN4,S100A13,SDC2,SEMA4B,SEMA6C,SKIL,UST,WASHC2C,WDPCP,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 687 | 71 | ARAP1,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CAPZB,CDC42,CDC42EP2,CORO1B,CRK,CUL7,CUX1,CXCR4,CYFIP1,CYLD,DAB2IP,DBN1,DMTN,EFNA1,EFNB3,EPS8L1,EPS8L2,ERMN,FGF13,GDI1,GRN,GSK3B,HGF,HRG,ILK,IQGAP1,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MARK4,MDK,NRCAM,PLEKHM1,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAB8B,RAPGEF1,RETREG3,RHOA,RHOG,RHOQ,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SKIL,TAPT1,TBC1D7,TGFBR1,TRPV4,UST,VIM,WASL,WDPCP,ZSWIM4,ZSWIM8 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 1220 | 97 | AKAP9,APP,ARAP1,ARPC3,ATG13,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CALCOCO2,CD151,CD63,CDC42,CDC42EP2,CORO1B,CRK,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,DAB2,DAB2IP,DBN1,DCN,DMTN,DSTN,DUSP3,DYNC1H1,EPS8L1,EPS8L2,FNIP1,GDI1,GMFG,GRN,GSK3B,HGF,HRG,ILK,INSR,IQGAP1,JDP2,LEPROT,LIMCH1,LRP1,LRSAM1,MACF1,MAP1B,MAP2K2,MAPK1,MARK4,MDK,MIEF2,MOAP1,MSN,MYADM,MYLK3,MYO1C,NEDD9,NPEPPS,OPTN,PCSK9,PINK1,PIP4K2C,PLEKHM1,PLEKHM2,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAB31,RAB8B,RAPGEF1,RETREG3,RHOA,RHOC,RHOQ,SCARB2,SDCBP,SH3GLB1,SIRT2,SKIL,SNX9,SWAP70,TAPT1,TGFBR1,TRPV4,UBE2B,ULK1,VPS11,WASHC2C,WASL,WBP2,YWHAZ,ZNF205 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 537 | 62 | APOD,ATG13,ATP13A2,BCAS3,CD81,CDC42,CEMIP,CHP1,CTNNB1,CYLD,DAB2,DMTN,EIF2AK3,FCER1G,GDI1,GLIS2,GLUL,GSK3B,INPP5K,INSIG1,IQGAP1,ITGB1,KCNE1,LEPROT,LGALS3,LRP1,MAP2,MAPK1,MARK4,MEAK7,MIEF2,MSN,MYO1C,NPEPPS,NUCB1,NUMB,OPHN1,OS9,PINK1,PKIG,PRKN,PRR5L,PSEN1,RAB11FIP5,RAB23,RHOG,RHOQ,RTN4,SH3GLB1,SNX33,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,TMBIM1,TMEM59,TP53INP2,TTBK2,VPS11,YWHAZ |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1962 | 128 | AACS,ACAN,ACAT1,ACAT2,ACO1,ACOT8,ACOX1,ACSL1,ACSS2,ADCY2,ADH5,AHCYL2,AKR1C3,ALDH6A1,ALKBH7,APOBR,APOC1,APOD,APP,ARNT,ASS1,ATP2B4,B3GNT2,CDA,CDIPT,CDS2,CEMIP,CHP1,CHPF,CLN3,CLN8,CSPG4,CTNS,CYB5R3,CYP2W1,CYP51A1,CYP8B1,DCN,DECR1,DHCR24,DYSF,EBP,EHHADH,ELOVL1,ERG28,FDFT1,FDPS,FN3K,GAA,GALNS,GK,GLUL,GNS,GSK3B,HADHA,HADHB,HECTD4,HGF,HK1,HMGCR,HMGCS1,HYAL3,IDH1,IDI1,INPP5K,INSIG1,INSR,IP6K1,LMBRD1,LPIN1,LPIN2,LSS,MAN2A1,MAN2A2,MAPK1,MAPKAPK2,MPC2,MSMO1,MST1,MT-ATP6,MT-ATP8,NAGK,NCOR2,NOS3,NQO1,NSDHL,NT5C2,OSBPL1A,OSBPL2,PC,PCSK9,PEPD,PGM1,PGM2L1,PHYH,PINK1,PLA2G15,PLOD2,PMM1,PPP1R3F,PRKN,PRXL2C,PSEN1,RAB23,RBKS,RETSAT,RHOA,RHOQ,SC5D,SCD,SCPEP1,SERINC3,SERINC5,SGPL1,SLC2A6,SMPD1,SMPDL3A,SOAT1,SORBS1,SPTLC1,STARD4,STAT5B,SULT1C2,TXNRD1,UPB1,UST,VNN1,WDTC1 |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 782 | 75 | ATP13A2,CACUL1,CAMLG,CD81,CLN8,CSNK1D,CTNNB1,CTSA,CTSB,CTSF,CUL7,CYLD,DAB2,DAB2IP,DACT1,DENND3,DNAJB2,DNAJC3,EFNA1,FAP,FBXL12,FBXL2,FURIN,GABARAPL2,GSK3B,KCTD10,KCTD21,LAMP2,LRP1,LRRC29,MSN,MTM1,MVB12B,NDFIP1,NRDC,OPHN1,OS9,PCSK9,PINK1,PRKN,PSEN1,PTTG1IP,RAB7A,RCN3,RGP1,RHBDF1,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SCPEP1,SDCBP,SHARPIN,SIRT2,SKP1,SMAD7,SPSB3,SQSTM1,TOLLIP,TP53INP2,TRPC4AP,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,USP11,USP6,USP9Y,VPS11,ZER1 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 802 | 76 | APOD,ATG13,ATP13A2,BCAS3,CAMK2D,CD81,CDC42,CEMIP,CHP1,CTNNB1,CYLD,DAB2,DENND10,DMTN,DYNC1H1,EIF2AK3,FCER1G,GDI1,GLIS2,GLUL,GSK3B,HMGCR,HMOX1,INPP5K,INSIG1,IQGAP1,ITGB1,KCNE1,LEPROT,LGALS3,LRP1,MAP1B,MAP2,MAP2K2,MAPK1,MARK4,MEAK7,MIEF2,MPC2,MSN,MYO1C,NPEPPS,NUCB1,NUMB,OPHN1,OS9,PCSK9,PINK1,PKIG,PRKN,PRR5L,PSEN1,RAB11FIP5,RAB23,RHOG,RHOQ,RHOT1,RTN4,SH3GLB1,SNX33,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,STXBP2,TMBIM1,TMEM38A,TMEM59,TP53INP2,TRPM4,TTBK2,VPS11,YIPF5,YWHAZ |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 942 | 83 | AKAP13,AKAP9,APOD,APP,ARAP1,ARPC3,ATP13A2,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CAPG,CAPZB,CDC42,CDC42EP2,CEP295NL,CHMP1B,CHMP2A,CORO1B,CORO2B,CYFIP1,CYLD,DAB2IP,DACT1,DBN1,DMTN,DNAJB2,DUSP3,DYNC1H1,EPS8L1,EPS8L2,FBLIM1,FNIP1,GMFG,GSK3B,HRG,INPP5K,IQGAP1,KANK1,LIMCH1,LRP1,LRSAM1,MACF1,MAP1B,MAP2,MARK4,MIEF2,MSN,MTM1,MTMR3,MYADM,MYLK3,MYO1C,PEAK1,PINK1,PIP4K2C,PLEKHM1,PPP2R5B,PRKN,PTPRD,RAB7A,RAPGEF1,RHOA,RHOC,RHOG,RHOQ,SAMD8,SDCBP,SH3GLB1,SIRT2,SNX9,SPTBN1,SWAP70,TAPT1,TBC1D12,TBC1D7,TGFBR1,ULK1,VPS11,WASHC2C,WASL,WDPCP |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 1703 | 117 | ABR,ACVR1,ADAM17,ADAMTSL2,APOD,ATP2B4,CALCRL,CASTOR2,CASTOR3,CAVIN3,CD109,CDC42,CHP1,CORO1B,CREBRF,CRK,CTNNA1,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,DCN,DNAJC3,DUSP3,EFNA1,EPS15,ERCC6,FAM89B,FAP,FNDC4,FNIP1,GLG1,GLIS2,GNAI2,GPR161,GRAMD4,GRINA,GRN,GSK3B,HGF,HIPK3,HMGCR,HMOX1,HRG,IGBP1,IGFBP6,INPP5K,INSIG1,ITGA1,ITGAV,ITGB1,KANK1,KCTD10,KCTD21,LATS2,LBH,LEPROT,LGALS3,LITAF,LMBR1L,LRP1,LY96,MDK,MEAK7,MICA,MTM1,MYADM,NCOR2,NDFIP1,NOS3,OPTN,OS9,PHLDA3,PIK3IP1,PINK1,PLXNA3,PPEF2,PPM1N,PPP2R5B,PRKN,PROS1,PRR5L,PSAP,PSEN1,PTPRR,PTTG1IP,RAB7A,RAPGEF1,RHOA,SEMA4B,SEMA6C,SHARPIN,SIRPA,SIRT2,SKIL,SMAD7,SMPD1,SNX6,TANK,TAOK3,TBC1D7,TGFBR1,TIMP2,TMBIM1,TMEM127,TMEM88,TNFRSF14,TNFSF4,TSC2,TWSG1,UBE2B,UBR2,UBXN1,VASN,VNN1,WNT5B |
| GO_IMPORT_INTO_CELL | 0.0e+00 | 0.0e+00 | 1229 | 810 | 76 | AAK1,ACSL1,ACTG1,APOBR,APOC1,APP,ATP2B4,ATP9A,BTBD8,BTBD9,CALCRL,CAP1,CD151,CD63,CD81,CDC42,CLN3,CLN8,CLTCL1,CYTH2,DAB2,DGKD,EPS15,ESYT2,FCER1G,FCHO2,FNBP1,GLUL,HEATR5B,IGF2R,IGHV3-74,INSR,ITGB1,KIAA1109,LGALS3,LMBR1L,LRP1,LRP10,LRSAM1,MAPK1,MAPKAPK2,MFGE8,NECAP2,NUMB,OPHN1,PCSK9,PDLIM7,PIP5K1C,PLA2R1,PRG4,PRKN,PSEN1,RAB31,RAB4B,RAB5B,RAB7A,RABGAP1L,RHOG,RHOQ,RUBCN,SCARB2,SDCBP,SLC12A4,SLC12A6,SLC22A3,SLC2A5,SNX33,SNX9,SYNGR3,TOM1,TRPM4,TSC2,WASL,XKR8,XKR9,ZFYVE16 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 1163 | 93 | ABR,ACVR1,AGO4,AKAP13,ARAP1,BAIAP2,C15orf62,CAPZB,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,CFAP410,CHI3L1,CORO1B,CRK,CST3,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,DAB2,DAB2IP,DACT1,DBN1,DCN,DMTN,EFNA1,EFNB3,ERMN,FBLIM1,FGF13,FOXO4,GDI1,GLUL,GPNMB,GRN,GSK3B,HDAC5,HGF,HMOX1,HRG,HTATIP2,ILK,ITGA7,ITGB1,JAK1,KANK1,KLF2,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MDK,MIEF2,MSN,MYADM,MYL12B,MYLK3,NEDD9,NOS3,NRCAM,PAX8,PINK1,PLEKHO1,PLXNA3,PRKN,PSEN1,PTPRD,RHOA,RHOC,RHOG,RHOQ,RRAS,RTN4,S100A13,SCX,SDC2,SEMA4B,SEMA6C,SKIL,STAT2,TGFBR1,TMBIM1,UST,VAT1,WASHC2C,WDPCP,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 534 | 61 | AKAP13,AKAP9,ARAP1,ARPC3,AVIL,BAIAP2,BCAS3,C15orf62,CAPG,CAPZB,CDC42,CDC42EP2,CDK2AP2,CEP295NL,CHMP1B,CHMP2A,CLIC4,CORO1B,CORO2B,CRK,CTNNB1,CYFIP1,CYLD,DBN1,DMTN,DSTN,DYNC1H1,FGF13,GMFG,GSK3B,HRG,ILK,INPP5K,KANK1,LIMCH1,LRP1,MAP1B,MAP2,MAPK1,MARK4,MDK,MYADM,MYLK3,MYO1C,NOTCH2,PLXNA3,PRKN,RHOA,RHOC,RHOG,RHOQ,SNX9,SPEF1,SPTBN1,SWAP70,TGFBR1,TRIM54,TRPV4,TTBK2,WASHC2C,WASL |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1229 | 1208 | 95 | AACS,ADCY2,ADH5,AKAP9,AKR1C3,APP,AQP9,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CALCRL,CASTOR2,CASTOR3,CDK19,COL6A1,CRK,CTNNA1,CTNNB1,CYFIP1,DAB2IP,DMTN,FBLN5,FBXO32,FOXO4,GNAI2,GNAS,GRAMD1A,GSK3B,HCN3,HDAC5,HGF,HMGCR,HMGCS1,INPP5K,INSIG1,INSR,ITPR2,KANK1,KCNE1,KLF11,KLF2,LAMTOR3,LEPROT,LITAF,LPIN1,LPIN2,LRP1,LY96,MAP1B,MAP1LC3A,MAPK1,MPC2,MSN,MYO1C,NOS3,NQO1,NR4A1,NRIP1,OSER1,PCSK9,PINK1,PRDX5,PRKN,PSAP,PSEN1,RAB11FIP5,RAB31,RAB8B,RAPGEF1,RHOA,RHOQ,RRAGC,SIRPA,SIRT2,SLC26A6,SLC2A5,SNX6,SORBS1,SPON2,STAT5B,TNFSF4,TP53INP1,TRAF6,TRPM4,TSC2,UBR2,VIM,WDTC1,WNT5B,ZNF277 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1229 | 1135 | 91 | AACS,ADCY2,AKAP9,APP,AQP9,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CASTOR2,CASTOR3,CD81,COL6A1,CRK,CTNNA1,CTNNB1,CXCR4,CYFIP1,DMTN,DNAJB2,EEF2,FCER1G,FOXO4,GNAI2,GNAS,GSK3B,HADHA,HCN3,HDAC5,HMGCS1,INPP5K,INSR,IQGAP1,ITGB1,ITPR2,KANK1,KCNE1,KLF11,KLF2,LAMTOR3,LEPROT,LPIN1,LPIN2,LRP1,MAP1B,MAP1LC3A,MAPK1,MEAK7,MT-ND5,MT-ND6,MYO1C,NCOR2,NQO1,NR4A1,OS9,P2RX6,PCSK9,PRKN,PSEN1,RAB31,RAB8B,RAPGEF1,RCN3,RFTN1,RHOA,RHOQ,RNF103,RRAGC,SIRT2,SLC26A6,SMPD1,SNX6,SORBS1,STAT2,STAT5B,STING1,TMEM38A,TNFSF4,TRPM4,TRPV4,TSC2,UBE4B,UBR2,UBXN1,UBXN6,VIM,WDTC1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1724 | 116 | ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,APP,ARNT,ATG13,ATP2B4,ATP6AP1,AUTS2,CACUL1,CAVIN3,CCNYL2,CD276,CD81,CDC42,CEMIP,CHI3L1,CHP1,CREBL2,CRK,CSNK1D,CSPG4,CTNNB1,CTSD,CXCR4,DAB2,DAB2IP,DACT1,DNAJB2,DNAJC3,DSTYK,EEF2,EFNA1,EIF2AK3,ERCC6,ERP29,FGF13,FNIP1,FURIN,FZD8,GNAI2,GOLGA2,GPNMB,GRAMD4,GRN,GSK3B,HGF,HMGCR,HMOX1,ILK,INSR,IQGAP1,ITGA1,JDP2,KLF2,LAMTOR3,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MSN,MST1R,NDFIP1,NEDD9,NOTCH2,NRDC,NSF,PCSK9,PINK1,PJA2,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTTG1IP,RAB7A,RAPGEF1,RCN3,RHOA,RILP,RNF14,RPS27L,SDCBP,SIRT2,SMAD7,SMPD1,SNX33,SNX9,SOAT1,SPAG9,SQSTM1,STAT5B,TANK,TAOK3,TBC1D7,TGFBR1,TIMP2,TNFRSF14,TOLLIP,TRAF6,TRPV4,TWSG1,VIM,VPS11,WBP2,ZER1 |
| GO_MEMBRANE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 875 | 77 | AAK1,ACTG1,ALKBH7,ANXA6,ARPC3,ATP10D,ATP11A,ATP9A,BAIAP2,CDC42,CERT1,CHMP1B,CHMP2A,CHP1,CHRNB1,CLN3,CLN8,CLTCL1,CSNK1D,CXCR4,DAB2,DHCR24,DMKN,DYSF,EPS15,FCER1G,FCHO2,FNBP1,GOLGA2,GSK3B,HEBP2,IGF2R,IGHV3-74,INSIG1,LPIN1,MFGE8,MOAP1,MT-ATP6,MT-ATP8,MYADM,NRCAM,NSF,OSBPL2,PINK1,PIP5K1C,PLEKHM2,PRKN,PSAP,PTPRD,RAB31,RAB7A,RAB8B,RFTN1,RHOA,RHOG,RHOT1,RILP,RTN4,SCARB2,SH3GLB1,SNAP23,SNX33,SNX9,SPTBN1,STX3,STX7,STX8,TLCD2,TMEM102,TMEM43,TRAPPC6A,VPS11,WASL,XKR8,XKR9,YWHAZ,ZNF205 |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 569 | 61 | ABR,AKAP13,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,AUTS2,C15orf62,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,CHM,CHP1,CRK,CYFIP1,CYTH1,CYTH2,DAB2IP,DHCR24,EPS8L1,EPS8L2,GDI1,GMIP,HMOX1,IFT27,ITGB1,KANK1,KCTD10,MADD,NOTCH2,OPHN1,PSD4,RAB23,RAB31,RAB32,RAB43,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RALGDS,RAPGEF1,RHOA,RHOC,RHOG,RHOQ,RHOT1,RRAGC,RRAS,RRAS2,SHOC2,SQSTM1,TIAM2,TIMP2,TSC2 |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 1287 | 96 | ABR,ALS2CL,APLP2,APOC1,APP,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ASAP2,ATP13A2,BCAS3,CAMK2D,CD109,CDC42EP2,CDC42SE1,CHM,CHP1,CRK,CST3,CSTB,CTSD,DAB2IP,DHCR24,DNAJB2,EFNA1,EIF2AK3,FNIP1,FURIN,GABARAPL2,GDI1,GIT2,GMIP,GNAI2,GRAMD4,GRN,GSK3B,HGF,HRG,IGBP1,IQGAP1,ITGA1,ITGB1,KDM5A,LGALS3,LRP1,MAP2,MICAL1,NEDD9,NOS3,NRDC,NUAK1,OPHN1,PINK1,PLA2R1,PLXNA3,PPP2R5B,PRDX5,PROS1,PSAP,RABGAP1,RABGAP1L,RAPGEF1,RASAL2,RCN3,RGP1,RHOA,RHOC,RHOG,RP2,RPS27L,SCARB2,SERPINB1,SERPINB6,SHOC2,SNX9,STXBP5,TANK,TBC1D12,TBC1D17,TBC1D19,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,TIAM2,TIMP2,TRAPPC6A,TSC2,UBXN1,USP6,ZFYVE1 |
| GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 436 | 53 | AKAP9,ALS2CL,ANXA6,ARHGAP21,BAIAP2,BCAS3,CDC42,CERT1,CHMP1B,CHMP2A,CLCN3,CSNK1D,CUL7,CXCR4,DMKN,DYSF,EIF2AK3,GOLGA2,GOLGA8N,GOLGB1,LPIN1,LYST,MAP2K2,MAPK1,OPTN,OSBPL2,PDE4DIP,PI4K2A,PLEKHM2,PRKN,PSAP,RAB43,RAB5B,RAB7A,RILP,RTN4,SCARB2,SH3GLB1,SNX33,SNX9,SPTBN1,SQSTM1,TLCD2,TMED4,TMEM127,TMEM38A,TMEM43,TRAPPC8,VPS11,WASL,XKR8,XKR9,YWHAZ |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 766 | 71 | ABI1,ABR,ACTG1,AKAP13,AKAP9,ARAP1,ARPC3,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CAMK2D,CAP1,CAPG,CAPZB,CAVIN3,CDC42,CDC42EP2,CORO1B,CORO2B,CRK,CYFIP1,CYTH2,DBN1,DMTN,DSP,DSTN,EHBP1L1,ERMN,FGF13,GMFG,HRG,ILK,INPP5K,ITGB1,KANK1,KCNE1,LIMCH1,LRP1,MDK,MICAL1,MYADM,MYL6,MYL6B,MYLK3,MYO1C,NEDD9,NOTCH2,OPHN1,PALLD,PDLIM7,PIP5K1C,PRKN,RHOA,RHOC,RHOG,RHOQ,SDCBP,SNX9,SORBS1,SPTBN1,SWAP70,TGFBR1,TRPM4,TRPM7,TRPV4,VIM,WASHC2C,WASHC3,WASL |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1064 | 85 | AACS,ABHD2,ACAT1,ACAT2,ACOT8,ACOX1,ACSL1,ACSS2,ADH5,AKR1C3,ALKBH7,AMBRA1,APOBR,APOC1,APOD,CD81,CDC42,CDIPT,CDS2,CERT1,CLN8,CPNE3,CTSA,DAB2IP,DECR1,DGKD,EHHADH,ELOVL1,ERG28,ESYT1,ESYT2,FDFT1,FDPS,GK,GPCPD1,HADHA,HADHB,HMGCR,HMGCS1,IDH1,IDI1,INPP5K,INSIG1,IP6K1,LPIN1,LPIN2,LRP1,LSS,MBOAT2,MSMO1,MTM1,MTMR3,NEU1,PCSK9,PHYH,PI4K2A,PIGG,PIK3IP1,PIP4K2C,PIP5K1C,PITPNM1,PLA2G15,PLPP1,PNPLA2,PNPLA6,PSAP,RETSAT,RUBCN,SAMD8,SCD,SCPEP1,SDC2,SERINC1,SERINC2,SERINC3,SERINC5,SGPL1,SIRT2,SLC22A4,SMPD1,SOAT1,SPTLC1,STARD4,TMEM150A,WDTC1 |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1180 | 90 | AGO4,ATP13A2,CACUL1,CAMLG,CD81,CLN8,CSNK1D,CST3,CTNNB1,CTSA,CTSB,CTSF,CUL7,CYLD,DAB2,DAB2IP,DACT1,DEDD2,DENND3,DNAJB2,DNAJC3,DNASE1,DNASE1L1,DNASE2,EFNA1,FAP,FBXL12,FBXL2,FURIN,GABARAPL2,GSK3B,KCTD10,KCTD21,LAMP2,LRP1,LRRC29,MANBA,MAPKAPK2,MSN,MTM1,MVB12B,NDFIP1,NRDC,OPHN1,OS9,PCSK9,PINK1,PRKN,PRR5L,PSEN1,PTTG1IP,RAB7A,RCN3,RGP1,RHBDF1,RNASEH2C,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SCPEP1,SDCBP,SHARPIN,SIRT2,SKP1,SMAD7,SMG6,SPSB3,SQSTM1,TOLLIP,TP53INP2,TRPC4AP,TUT7,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,USP11,USP6,USP9Y,VIM,VPS11,YWHAZ,ZER1,ZHX2 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1229 | 1748 | 114 | ABR,ACVR1,ADAM17,AGO4,AKAP13,AKR1C3,ALX3,AMBRA1,ANXA4,ARHGAP10,ARHGEF12,ARHGEF6,ARNT2,ATP13A2,CAMK2D,CDC42,CDK19,CHM,CHMP2A,CHP1,CLN3,CLN8,CTNNA1,CTNNB1,CTSB,CTSD,CXCR4,CYLD,DAB2,DAB2IP,DEDD2,DHCR24,DNAJC3,DSTYK,EFNA1,EIF2AK3,ERC1,ERP29,FANK1,FAP,FCER1G,FNIP1,GNAI2,GPNMB,GRAMD4,GRINA,GRN,GSK3B,HEBP2,HGF,HIPK3,HMGCR,HMOX1,HRG,HTATIP2,IFIT3,IGBP1,IGF2R,ILK,ING4,ITGA1,ITGAV,ITGB1,KIFAP3,KLF11,LATS2,LGALS3,LRP1,MADD,MAP3K10,MARK4,MDK,MEAK7,MICAL1,MOAP1,NCOA1,NOS3,NOTCH2,NQO1,PAX8,PCSK9,PHLDA3,PINK1,PRDX5,PRKN,PSAP,PSEN1,PTTG1IP,RHOA,RPS27L,RRAS2,RTN4,SAV1,SCX,SERINC3,SIRT2,SKIL,SMPD1,SNX6,SPTLC1,SQSTM1,STAT5B,TGFBR1,TIAM2,TMBIM1,TMEM102,TP53I3,TP53INP1,TRAF6,TRIM35,UBE2B,VNN1,YWHAZ,ZNF205 |
| GO_REGULATION_OF_AUTOPHAGY | 0.0e+00 | 0.0e+00 | 1229 | 328 | 45 | AMBRA1,ATG13,ATP13A2,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALCOCO2,CAPN1,CAPNS1,CTSA,DCN,DEPP1,EXOC1,EXOC4,FBXL2,GOLGA2,GSK3B,HGF,HMOX1,KDM4A,LAMTOR3,LRSAM1,MTM1,MTMR3,OPTN,PINK1,PIP4K2C,PRKN,PSAP,RRAGC,RUBCN,SH3GLB1,SIRT2,SNX6,SPTLC1,STING1,TBC1D12,TMEM150A,TMEM59,TP53INP1,TP53INP2,TRIM21,TSC2,ULK1 |
| GO_ENDOCYTOSIS | 0.0e+00 | 0.0e+00 | 1229 | 661 | 64 | AAK1,ACTG1,APOBR,APOC1,APP,ATP9A,BTBD8,BTBD9,CALCRL,CAP1,CD151,CD63,CD81,CDC42,CLN3,CLTCL1,CYTH2,DAB2,DGKD,EPS15,ESYT2,FCER1G,FCHO2,FNBP1,HEATR5B,IGF2R,IGHV3-74,INSR,ITGB1,KIAA1109,LGALS3,LMBR1L,LRP1,LRP10,LRSAM1,MAPK1,MAPKAPK2,MFGE8,NECAP2,NUMB,OPHN1,PCSK9,PDLIM7,PIP5K1C,PLA2R1,PRG4,RAB31,RAB4B,RAB5B,RAB7A,RABGAP1L,RHOG,RHOQ,RUBCN,SCARB2,SDCBP,SNX33,SNX9,TOM1,TSC2,WASL,XKR8,XKR9,ZFYVE16 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 724 | 67 | APOC1,APOD,ARAP1,AVIL,BCAS3,CAPG,CAPZB,CDC42,CHMP2A,CORO1B,CORO2B,CST3,DACT1,DMTN,DNAJB2,EFNA1,EFNB3,FAP,FGF13,FNIP1,GDI1,GMFG,GSK3B,HGF,HRG,INPP5K,INSIG1,KANK1,KDM5A,LGALS3,LRP1,LRSAM1,MAP1B,MAP2,MTM1,MYADM,PCSK9,PINK1,PLXNA3,PMP22,PRKN,PSEN1,RAB7A,RHOA,RTN4,RUBCN,SDCBP,SEMA4B,SEMA6C,SIRT2,SMG6,SNX33,SPEF1,SPTBN1,SWAP70,TBC1D7,TINF2,TRIM54,TRPV4,TSC2,TTBK2,UBE2B,ULK1,VAT1,VIM,WASHC2C,WASL |
| GO_AUTOPHAGOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 95 | 26 | AMBRA1,ATG13,ATG2B,ATP13A2,GABARAP,GABARAPL2,LRSAM1,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MTM1,MTMR3,PINK1,PIP4K2C,PSEN1,RAB23,RAB7A,SH3GLB1,STING1,TBC1D12,TP53INP1,TP53INP2,TRAPPC8,ULK1,WDR45,WIPI1 |
| GO_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1180 | 88 | AHNAK,AKAP9,ANO10,ANXA6,APP,ATP10D,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BEST1,CALCRL,CAMK2D,CAPN1,CD63,CEMIP,CHP1,CHRNB1,CLCN3,CLN3,COX6A1,COX6C,CP,CTNNB1,CXCR4,DYSF,FCER1G,FGF13,FTH1,FTL,GNAI2,GRIN2D,HCN3,HRG,INPP5K,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,LGALS3,MAGED2,MCOLN1,MCOLN3,MICU1,MT-ATP6,MT-ATP8,NDFIP1,NIPA1,NOS3,NSF,P2RX6,PCSK9,PINK1,PRKN,PSEN1,REP15,RHOA,SARAF,SESTD1,SLC10A6,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC17A5,SLC22A3,SLC22A4,SLC2A6,SLC31A2,SLC38A2,SLC38A7,SLC39A13,SLC41A2,SNAP23,SYT15,TMCO3,TMEM165,TMEM38A,TMEM63B,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1229 | 847 | 72 | ACTG1,ACVR1,ASS1,BAIAP2,CD164,CD276,CD81,CDC42,CDH9,CERCAM,COL13A1,CTNNA1,CTNNB1,CYLD,DMTN,DSP,DUSP3,EFNB3,FBLIM1,GNAS,GPNMB,ILK,ITGA7,ITGAV,ITGB1,KIFAP3,LGALS3,LPP,MADCAM1,MAP3K8,MDK,MSN,MYADM,MYL12A,NDFIP1,NFAT5,NRCAM,PALLD,PCDHB10,PCDHB13,PCDHB14,PCDHB15,PCDHB9,PCDHGA1,PCDHGA10,PCDHGA11,PCDHGA5,PCDHGA6,PCDHGA7,PCDHGA9,PCDHGB2,PCDHGB7,PCDHGC4,PIP5K1C,PSEN1,PTPRD,RAPGEF1,RHOA,S100A11,SIRPA,SIRPB1,SMAD7,SPARCL1,STAT5B,SWAP70,TNFRSF14,TNFSF4,TRAF6,TRPV4,TWSG1,VNN1,ZMIZ1 |
| GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 447 | 51 | ABR,AKAP13,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,AUTS2,C15orf62,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,CRK,CYFIP1,CYTH1,CYTH2,DAB2IP,DHCR24,EPS8L1,EPS8L2,GDI1,IFT27,ITGB1,KANK1,KCTD10,MADD,NOTCH2,OPHN1,PSD4,RAB23,RAB31,RAB32,RAB43,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RALGDS,RAPGEF1,RHOA,RHOC,RHOG,RHOQ,RHOT1,RRAS,RRAS2,SHOC2,SQSTM1,TIAM2,TIMP2 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 1881 | 116 | AAMDC,ACVR1,AGO4,AKAP13,APP,ARNT,ATP6AP1,AVIL,BAIAP2,BBS12,CD109,CDC42,CREBL2,CRK,CSNK1D,CTDP1,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,CYLD,DAB2,DAB2IP,DBN1,DMTN,EFNA1,EFNB3,FGF13,FNIP1,FOXO4,GDI1,GLG1,GNAS,GRN,GSK3B,HDAC5,HES6,HGF,IGSF10,ILK,INSIG1,IQGAP1,ITGAV,ITGB1,JDP2,KANK1,KIAA1109,KLF13,KMT2C,LBH,LGALS3,LRP1,LTBP3,LZTS3,MACF1,MAN2A1,MAP1B,MAP2,MAP2K2,MAPK1,MDK,MYADM,MYLK3,NCOA1,NDFIP1,NEDD9,NOTCH2,NRCAM,NUMB,PAX8,PDLIM7,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RTN4,SAV1,SCARB2,SDC2,SDCBP,SEMA4B,SEMA6C,SIRT2,SKIL,SMAD7,SPAG9,STAT5B,TCTA,TGFBR1,TIMP2,TNFSF4,TP53INP1,TRAF6,TRIP4,TRPM4,TRPV4,TWSG1,UST,VASN,VIM,VNN1,WASHC2C,WNT5B,ZFHX3,ZHX2,ZMIZ1,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE | 0.0e+00 | 0.0e+00 | 1229 | 367 | 46 | ARPC3,ATP13A2,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42EP2,CLCN3,CLCN6,CLN8,CORO1B,CYFIP1,DBN1,DMTN,DSTN,FGF13,GDI1,GMFG,GSK3B,ILK,KANK1,LRP1,LRRC8A,MACF1,MAP1B,MAP2,MSN,MYADM,MYO1C,NRCAM,PLXNA3,RHOA,RILP,RTN4,SEMA4B,SEMA6C,SLC12A4,SLC12A6,SNX9,SPTBN1,SWAP70,TRPV4,WASHC2C,WASL,WDTC1 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1005 | 79 | ACAT1,ACAT2,ACO1,ACOT8,ACOX1,ACSS2,ADH5,AKR1C3,ALDH6A1,ALKBH7,APOD,BLVRB,CAVIN3,COX6A1,COX6C,CP,CYB561D2,CYB5R3,CYBRD1,CYP2W1,CYP51A1,CYP8B1,DECR1,DHCR24,DHRS4L1,DHRS7,EHHADH,ETHE1,FMO4,FMO5,FTH1,FTL,GAA,GNAS,GSK3B,HADHA,HADHB,HK1,HMGCR,HMOX1,HSD17B11,HSD17B2,HTATIP2,IDH1,INPP5K,INSR,KDM4A,KDM4B,KDM5A,KDM5B,MICAL1,MSMO1,MT-ND2,MT-ND5,MT-ND6,NCF2,NOS3,NQO1,NSDHL,P4HA3,PAOX,PGLS,PGM1,PGM2L1,PHYH,PINK1,PLOD2,PPP1R3F,PRDX5,PRXL2C,RBKS,RETSAT,SC5D,SCD,SORBS1,TP53I3,TRPV4,TXNRD1,VAT1 |
| GO_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 835 | 71 | ABRAXAS1,ACTG1,AKAP13,AKAP9,AMBRA1,ATG13,ATG2B,ATP6V1D,AVIL,CEP126,CEP295NL,CETN2,CFAP410,CHMP1B,CHMP2A,CSNK1D,CYLD,DCTN2,DYNC1H1,GABARAP,GABARAPL2,GOLGA2,GOLGA8N,HPS1,IFT27,ITGB1,KIF3C,KIFAP3,LRSAM1,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MARK4,MSN,MTM1,MTMR3,MYLK3,OFD1,PINK1,PIP4K2C,PSEN1,PTPRD,RAB23,RAB32,RAB7A,RHOA,RP1L1,RPS10P5,RPS27L,RSPH9,SDCBP,SH3GLB1,STING1,STX7,TAPT1,TBC1D12,TBC1D7,TP53INP1,TP53INP2,TPGS1,TRAPPC6A,TRAPPC8,TTBK2,TTLL3,UBE2B,ULK1,VPS11,WDPCP,WDR19,WDR45,WIPI1 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 976 | 77 | ABI1,ACSL1,ADAM17,ADCY2,AKAP13,AMBRA1,APP,ATG13,ATP2B4,CACUL1,CCNG1,CCNI,CCNYL2,CD81,CDC42,CEMIP,CHI3L1,CHP1,CRK,CSPG4,CTNNB1,CXCR4,DAB2IP,DNAJC3,DSTYK,DUSP3,EFNA1,ERCC6,ERP29,FGF13,FZD8,GMFG,GOLGA2,GSK3B,HGF,HIPK3,HMGCR,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,LATS2,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1,MST1R,NEDD9,PIK3IP1,PINK1,PKIG,PPEF2,PPP1R3F,PRKN,PSEN1,RAPGEF1,RHOA,RUBCN,SERINC1,SERINC2,SERINC5,SH3BP5,SMAD7,SMG6,SMPD1,SNX6,SNX9,SPAG9,TAOK3,TGFBR1,TRAF6,TSC2 |
| GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 431 | 49 | AMBRA1,APP,ARNT,CALCOCO2,CD81,CSNK1D,DAB2,DAB2IP,DACT1,DCN,DNAJB2,FURIN,GSK3B,HMOX1,INSR,LRP1,LRSAM1,MSN,NDFIP1,NRDC,NSF,OPTN,PCSK9,PINK1,PIP4K2C,PNPLA2,PRKN,PRR5L,PRXL2C,PSEN1,PTTG1IP,RAB7A,RILP,RNF14,SH3GLB1,SIRT2,SMAD7,SNX33,SNX9,SPTLC1,STING1,TMEM59,TP53INP1,TP53INP2,TRIM21,TSC2,ULK1,VPS11,ZER1 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1189 | 86 | ACOT8,AGO4,APLP2,APOD,APP,ATP13A2,ATP2B4,CAMLG,CD109,CHP1,CLN3,CLN8,CRTAP,CST3,CSTB,CTDSP2,CTNNB1,CTSA,CYLD,CYP51A1,DAB2IP,DACT1,DHCR24,DMTN,DNAJC3,DUSP3,DYSF,EFNA1,EIF2AK3,FNIP1,FURIN,GABARAPL2,GLG1,GMFG,GNAI2,GSK3B,HGF,HIPK3,HMGCR,HRG,IGBP1,ILK,INPP5K,ITGAV,KDM5A,LATS2,LGALS3,LRP1,LRRK1,MICAL1,MTM1,MYADM,OPHN1,OS9,PINK1,PKIG,PPEF2,PRDX5,PRKN,PROS1,PRR5L,PSEN1,PTPRR,RAPGEF1,RGP1,RILP,SDCBP,SERPINB1,SERPINB6,SH3BP5,SHFL,SIRPA,SIRT2,SMAD7,SMPD1,SNX6,SQSTM1,SWAP70,TAOK3,TIMP2,TINF2,TMEM59,TRIM21,TSC2,UBE2B,UBXN1 |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1229 | 1427 | 96 | ACVR1,ADAM17,ADAMTSL2,APOD,ATP2B4,CASTOR2,CASTOR3,CAVIN3,CD109,CDC42,CHP1,CREBRF,CTNNA1,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,DCN,DUSP3,EFNA1,EPS15,FAM89B,FNIP1,GLG1,GLIS2,GNAI2,GPR161,GRAMD4,GRINA,GSK3B,HGF,HIPK3,HMGCR,HMOX1,HRG,IGBP1,IGFBP6,INPP5K,INSIG1,ITGA1,ITGAV,ITGB1,KANK1,KCTD10,KCTD21,LATS2,LBH,LEPROT,LGALS3,LITAF,LMBR1L,LRP1,LY96,MDK,MTM1,MYADM,NCOR2,NOS3,OPTN,PCSK9,PHLDA3,PIK3IP1,PINK1,PPEF2,PPM1N,PPP2R5B,PRKN,PRR5L,PSEN1,PTPRR,PTTG1IP,RAB11FIP5,RAB7A,RAPGEF1,RHOA,SIRPA,SKIL,SMAD7,SMPD1,SNX6,TANK,TAOK3,TBC1D7,TGFBR1,TIMP2,TMBIM1,TMEM127,TMEM88,TSC2,TWSG1,UBE2B,UBR2,VASN,VNN1,WNT5B |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 366 | 45 | AMBRA1,APP,ARNT,CALCOCO2,CD81,CSNK1D,DAB2,DAB2IP,DACT1,DCN,DNAJB2,FURIN,GSK3B,HMOX1,INSR,LRP1,LRSAM1,MSN,NRDC,OPTN,PCSK9,PINK1,PIP4K2C,PNPLA2,PRKN,PRR5L,PRXL2C,PSEN1,PTTG1IP,RNF14,SH3GLB1,SIRT2,SMAD7,SNX33,SNX9,SPTLC1,STING1,TMEM59,TP53INP1,TP53INP2,TRIM21,TSC2,ULK1,VPS11,ZER1 |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1604 | 103 | ABCA9,ABCC10,ABCC11,AHNAK,AKAP9,ANO10,ANXA6,APP,AQP9,ATP10D,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BEST1,CAMK2D,CAPN1,CD63,CEMIP,CHP1,CHRNB1,CLCN3,CLCN6,CLCN7,CLIC4,CLN8,CLTCL1,COX6A1,COX6C,CREBL2,CTNS,DMTN,DYSF,GJB7,GJD3,GRIN2D,HCN3,INPP5K,INSR,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,LRRC8A,MCOLN1,MCOLN3,MFSD1,MFSD12,MFSD14A,MICU1,MPC2,MT-ATP6,MT-ATP8,NIPA1,OS9,OSTM1,P2RX6,PCSK9,PEX6,PINK1,PSEN1,RAB4B,RHOQ,RTN2,SESTD1,SLC10A6,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC16A13,SLC17A5,SLC22A15,SLC22A3,SLC22A4,SLC26A11,SLC26A4,SLC26A6,SLC29A3,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC38A2,SLC38A7,SLC39A13,SLC41A2,SLC43A2,SLC4A3,SORBS1,SPNS1,TMCO3,TMEM38A,TMEM63B,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 1365 | 93 | ABI1,APOD,APP,AUTS2,AVIL,B3GNT2,BAIAP2,BTBD8,CDC42,CLN8,CRK,CSNK1D,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,DOK4,EFNA1,EFNB3,ERCC6,FGF13,FRYL,FZD8,GDI1,GRN,GSK3B,HDAC5,HGF,IFT27,ILK,IQGAP1,ITGA1,ITGB1,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,MCOLN3,MDK,NCOA1,NRCAM,NUMB,NYAP1,OPHN1,PALLD,PCSK9,PDLIM7,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RHOG,RP1L1,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SKIL,SPAG9,SPTBN1,STX3,TBC1D23,TGFBR1,TIMP2,TOP2B,TRPV4,UBE4B,ULK1,UST,VIM,WASL,WDPCP,WNT5B,YWHAZ,ZFHX3,ZHX2,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 387 | 46 | AKAP13,AKAP9,ARAP1,ARPC3,AVIL,BAIAP2,BCAS3,C15orf62,CAMK2D,CAPG,CAPZB,CDC42,CDC42EP2,CORO1B,CORO2B,CRK,CYFIP1,DBN1,DMTN,DSP,DSTN,FGF13,GMFG,HRG,ILK,INPP5K,KANK1,LIMCH1,LRP1,MDK,MYADM,MYLK3,MYO1C,NOTCH2,PRKN,RHOA,RHOC,RHOG,RHOQ,SNX9,SPTBN1,SWAP70,TGFBR1,TRPM4,WASHC2C,WASL |
| GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 547 | 55 | AAK1,ABR,APBA2,APOC1,ATP13A2,ATP6AP1,BTBD9,CD151,CD63,CHMP2A,CYFIP1,DAB2,DENND10,DYSF,FCER1G,GNAI2,GSK3B,HMOX1,HYAL3,INSIG1,ITGAV,LGALS3,LRP1,LRSAM1,MAP2K2,MAPK1,MFGE8,MICAL1,MSN,NSF,NUMB,OPHN1,PCSK9,PRKN,RAB31,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A,RAPGEF1,RUBCN,SDCBP,SIRPA,SIRPB1,SNX33,STXBP2,STXBP5,SYT15,TSC2,USP6,VPS11,WASL,YIPF5,ZFYVE16 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 748 | 65 | ABI1,APP,AUTS2,B3GNT2,BAIAP2,CDC42,CLIC4,COL6A1,COL6A2,CRK,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,DBN1,DMTN,DOK4,EFNA1,EFNB3,FGF13,GDI1,GSK3B,ILK,ITGAV,ITGB1,KANK1,LAMC1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,MATN3,MDK,MEGF9,MYADM,NEDD9,NRCAM,NUMB,OPHN1,PALLD,PDLIM7,PEAK1,PLXNA3,PSEN1,PTPRD,RHOA,RHOG,RTN4,SDC2,SEMA4B,SEMA6C,SKIL,SPTBN1,TOP2B,ULK1,UST,WASHC2C,WASL,WDPCP,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 0.0e+00 | 0.0e+00 | 1229 | 503 | 52 | ARPC3,ATP13A2,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42EP2,CLCN3,CLCN6,CLN8,CORO1B,CYFIP1,DBN1,DMTN,DSTN,FGF13,GDI1,GMFG,GSK3B,HMGCR,HMOX1,ILK,ITGA1,KANK1,LRP1,LRRC8A,MACF1,MAP1B,MAP2,MSN,MYADM,MYO1C,NOS3,NRCAM,PLXNA3,RHOA,RILP,RTN4,SCPEP1,SEMA4B,SEMA6C,SLC12A4,SLC12A6,SNX9,SPTBN1,SWAP70,TRPM4,TRPV4,WASHC2C,WASL,WDTC1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1247 | 87 | ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,APP,ARNT,ATG13,ATP2B4,ATP6AP1,AUTS2,CACUL1,CAVIN3,CCNYL2,CD81,CDC42,CEMIP,CHI3L1,CHP1,CREBL2,CRK,CSNK1D,CSPG4,CTNNB1,CXCR4,DAB2,DAB2IP,DSTYK,EFNA1,ERCC6,ERP29,FGF13,FNIP1,FZD8,GNAI2,GOLGA2,GPNMB,HGF,HMGCR,ILK,INSR,IQGAP1,ITGA1,JDP2,LAMTOR3,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NDFIP1,NEDD9,NOTCH2,PINK1,PJA2,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,PTTG1IP,RAPGEF1,RHOA,SDCBP,SMAD7,SMPD1,SNX9,SPAG9,SQSTM1,TANK,TAOK3,TBC1D7,TGFBR1,TIMP2,TNFRSF14,TOLLIP,TRAF6,TRPV4,TWSG1,WBP2 |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 984 | 75 | AACS,ABR,AKAP9,ATG13,ATP13A2,ATP6AP1,BCAS3,CD151,CD63,CD81,CDC42,CEMIP,CHMP2A,CHP1,CLTCL1,CREBL2,DAB2,DYNC1H1,EXOC1,FCER1G,FRMD4A,FRMD8,GALR1,GLUL,GNAI2,GSK3B,HK1,HYAL3,IL17RA,INPP5K,INSR,ITGAV,KCNE1,LEPROT,LGALS3,LRP1,MAP2,MAPK1,MDK,MFGE8,MIEF2,MPC2,MSN,MYO1C,NLRP10,NPEPPS,PCSK9,PINK1,PLA2R1,PRKN,PRR5L,PSEN1,RAB31,RAB7A,RAB8B,RAB9A,RAPGEF1,RHOQ,SDCBP,SH3GLB1,SIRPA,SIRPB1,SLC26A6,SORBS1,SPTBN1,STXBP5,SYNGR3,TNFRSF14,TNFSF4,TRPM4,TRPV4,VPS11,WASL,YWHAZ,ZNF205 |
| GO_CELLULAR_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1229 | 963 | 74 | AACS,ACO1,ANXA6,APP,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALB1,CAMK2D,CEMIP,CHP1,CLCN3,CLCN6,CLIC4,CLN3,CP,CXCR4,CYBRD1,DEDD2,DNAJB2,FTH1,FTL,GAA,GALR1,GRIN2D,GRINA,GRN,HK1,HMGCR,HMOX1,ITGAV,ITPR2,LAMP2,LRP1,LRRC8A,MAPK1,MCOLN1,MCOLN3,MICU1,MPC2,MTM1,NCF2,NCOA4,NDFIP1,NOS3,NQO1,PINK1,PRDX5,PRKN,PSEN1,RAB11FIP5,RAB7A,RHOT1,ROGDI,RTN4,SKP1,SLC12A4,SLC12A6,SLC26A6,SLC31A2,SLC39A13,SLC4A3,SWAP70,TMEM165,TMEM38A,TRPM4,TRPM7,TRPV4,TXNRD1,WDTC1 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1229 | 709 | 62 | ADCY2,AKAP9,APP,AQP9,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CASTOR2,CASTOR3,COL6A1,CRK,CTNNA1,CTNNB1,CYFIP1,DMTN,FOXO4,GNAI2,GNAS,GSK3B,HCN3,HDAC5,INPP5K,INSR,ITPR2,KANK1,KCNE1,KLF11,KLF2,LAMTOR3,LEPROT,LPIN1,LPIN2,LRP1,MAP1B,MAPK1,MYO1C,NR4A1,PCSK9,PRKN,PSEN1,RAB31,RAB8B,RAPGEF1,RHOQ,RRAGC,SIRT2,SLC26A6,SNX6,SORBS1,STAT5B,STING1,TMEM38A,TRPM4,TSC2,UBR2,VIM,WDTC1 |
| GO_RESPONSE_TO_HORMONE | 0.0e+00 | 0.0e+00 | 1229 | 994 | 75 | AACS,ABHD2,ACAT1,ACSL1,ADCY2,AKAP13,AKR1C3,ARNT2,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CALCOCO1,CREBRF,CRK,CTNNB1,CTSB,CYFIP1,DAB2,DHCR24,EEF2,FBXO32,FIBIN,FOXO4,GNAI2,GSK3B,HADHA,HDAC5,HMGCS1,IDH1,INPP5K,INSR,IQGAP1,KANK1,LATS2,LBH,LEPROT,LPIN1,LPIN2,MAP1B,MDK,MEAK7,MSN,MYO1C,NCOA1,NCOA4,NCOR2,NOS3,NQO1,NR4A1,NRIP1,PAX8,PCSK9,PLPP1,PRCP,RAB31,RAB8B,RHOA,RHOQ,RNF14,SORBS1,STAT2,STAT5B,TIMP2,TNFSF4,TRIP4,TRPV4,TSC2,UCN2,WBP2,WDTC1 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 1026 | 76 | AKAP13,AKR1C3,APP,ATP6AP1,AUTS2,CAVIN3,CD81,CDC42,CHI3L1,CRK,CSPG4,CTNNB1,CXCR4,DAB2IP,DCN,DSTYK,EFNA1,ERCC6,ERP29,FZD8,GNAI2,GPNMB,HGF,HMGCR,HMOX1,ILK,INSR,IQGAP1,ITGA1,ITGB1,LAMTOR3,LITAF,LMCD1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MIB2,MST1R,NDFIP1,NFAT5,NOTCH2,PINK1,PJA2,PLA2R1,PRKN,PRR5L,PRXL2C,PSAP,PSEN1,RAPGEF1,RHOA,RHOC,RHOG,RRAGC,RTN4,S100A13,SDCBP,SERINC3,SHARPIN,SHOC2,SIK3,SKIL,SPAG9,TAOK3,TGFBR1,TIMP2,TMED4,TRAF6,TRPV4,WDR59,ZDHHC17 |
| GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 348 | 42 | APOD,ATG13,ATP13A2,BCAS3,CD81,CDC42,CEMIP,CHP1,DAB2,DENND10,DMTN,DYNC1H1,FCER1G,GDI1,GSK3B,HMOX1,INPP5K,INSIG1,KCNE1,LEPROT,MAP1B,MAP2,MAP2K2,MAPK1,MIEF2,MSN,MYO1C,NPEPPS,NUCB1,OS9,PCSK9,PINK1,PKIG,PRKN,PRR5L,PSEN1,RAB23,RHOT1,SH3GLB1,STXBP2,VPS11,YIPF5 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1033 | 76 | ACAT1,ACOT8,ACSL1,ACSS2,ADCY2,AMBRA1,APOC1,APP,ARNT,CD81,CDA,CDC42,CDIPT,CDS2,CLN8,CPNE3,DAB2IP,ELOVL1,FDFT1,FDPS,GK,GPCPD1,HADHA,HADHB,HK1,HMGCR,HMGCS1,IDH1,IDI1,INPP5K,INSR,IP6K1,LPIN1,LPIN2,MAPK1,MBOAT2,MPC2,MT-ATP6,MT-ATP8,MTM1,MTMR3,NOS3,NT5C2,PCSK9,PGLS,PGM1,PGM2L1,PI4K2A,PIGG,PIK3IP1,PINK1,PIP4K2C,PIP5K1C,PITPNM1,PLA2G15,PLPP1,PNPLA6,PRXL2C,PSEN1,RAB23,RBKS,RHOA,RHOQ,RUBCN,SAMD8,SCD,SERINC1,SERINC2,SERINC3,SERINC5,SLC2A6,SMPD1,SMPDL3A,SPTLC1,SULT1C2,TMEM150A |
| GO_REGULATION_OF_MACROAUTOPHAGY | 0.0e+00 | 0.0e+00 | 1229 | 172 | 30 | ATG13,ATP13A2,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALCOCO2,CAPN1,CAPNS1,DCN,EXOC1,EXOC4,HMOX1,LAMTOR3,LRSAM1,MTM1,MTMR3,OPTN,PINK1,PIP4K2C,PRKN,RRAGC,RUBCN,SH3GLB1,SNX6,SPTLC1,STING1,TBC1D12,TSC2,ULK1 |
| GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 351 | 42 | AKAP13,AKAP9,APP,ARAP1,ARPC3,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42,CDC42EP2,CORO1B,CORO2B,CYFIP1,DBN1,DMTN,DSTN,FGF13,GMFG,INPP5K,KANK1,LIMCH1,MAP1B,MAP2,MYADM,MYLK3,MYO1C,PRKN,PSEN1,RHOA,RHOC,SNX9,SPEF1,SPTBN1,SWAP70,TGFBR1,TRIM54,TRPV4,TTBK2,WASHC2C,WASL |
| GO_CELL_PART_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 691 | 60 | ABI1,APP,AUTS2,B3GNT2,BAIAP2,CDC42,CERT1,CORO1B,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,DAB2IP,DBN1,DOK4,EFNA1,EFNB3,FGF13,GDI1,GSK3B,ILK,IQGAP1,ITGA1,ITGB1,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,MDK,MTM1,NRCAM,NUMB,NYAP1,OPHN1,PALLD,PDLIM7,PLEKHO1,PLXNA3,PRKN,PSEN1,PTPRD,RHOA,RHOG,RTN4,SDC2,SEMA4B,SEMA6C,SKIL,SPTBN1,TOP2B,ULK1,UST,WASL,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 388 | 44 | ATP13A2,CAMLG,CD81,CSNK1D,CST3,CTSA,CYP51A1,DAB2,DAB2IP,DACT1,DNAJB2,DYSF,EFNA1,FURIN,GABARAPL2,GSK3B,HMGCR,LRP1,MSN,MTM1,NDFIP1,NRDC,NSF,OPHN1,OS9,PCSK9,PINK1,PRKN,PSEN1,PTTG1IP,RAB7A,RGP1,RHBDF1,RILP,RNF14,SDCBP,SIRT2,SMAD7,SNX33,SNX9,TIMP2,UBXN1,VPS11,ZER1 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1825 | 108 | ACSL1,ACVR1,ADAM17,APP,ARNT,ATP6AP1,ATP6AP2,AVIL,BAIAP2,BCAS3,CAMK2D,CD276,CD81,CDC42,CHI3L1,CSNK1D,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,CYLD,DAB2,DAB2IP,DBN1,DECR1,DMTN,DYNC1H1,EIF2AK3,FCER1G,FRMD8,FURIN,GALR1,GDI1,GNAI2,GNAS,GRN,HGF,HK1,HMGCR,HMOX1,HRG,IL17RA,ILK,INPP5K,IQGAP1,ITGB1,JAK1,KDM5B,LBH,LPIN1,LRP1,LTBP3,LY96,MACF1,MAN2A1,MAP1B,MAP2K2,MAPK1,MAPKAPK2,MDK,MST1,MTM1,NCOA1,NLRP10,NOS3,NOTCH2,NRCAM,NUMB,PAX8,PDLIM7,PLEKHM1,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAB8B,RAPGEF1,RETREG3,RHOA,RRAS,RTN4,SCARB2,SCD,SCX,SDCBP,SIRT2,SKIL,SLAMF6,SPAG9,SPON2,SPTBN1,STAT5B,STING1,TAPT1,TBC1D23,TGFBR1,TIMP2,TMBIM1,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4,VNN1,ZMIZ1 |
| GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 390 | 44 | ARAP1,AUTS2,AVIL,BAIAP2,BCAS3,C15orf62,CDC42,CDC42EP2,CORO1B,CUL7,CUX1,CXCR4,CYFIP1,DAB2IP,DBN1,EPS8L1,EPS8L2,GDI1,GRN,HGF,ILK,IQGAP1,LRP1,MACF1,MAP1B,MAP2K2,MARK4,MDK,PLEKHM1,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAB8B,RAPGEF1,RETREG3,RHOA,RHOQ,SCARB2,SKIL,TAPT1,TGFBR1,WASL |
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 1625 | 100 | ABI1,APOD,APP,AUTS2,AVIL,B3GNT2,BAIAP2,BTBD8,CDC42,CLN8,CRK,CSNK1D,CSPG4,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,DOK4,EEF2,EFNA1,EFNB3,ERCC6,FGF13,FRYL,FZD8,GDI1,GRN,GSK3B,HDAC5,HES6,HGF,IFT27,IGSF10,ILK,IQGAP1,ITGA1,ITGB1,KANK1,LRP1,LZTS3,MACF1,MAN2A1,MAP1B,MAP2,MAP2K2,MAPK1,MCOLN3,MDK,NCOA1,NRCAM,NUMB,NYAP1,OPHN1,PALLD,PCSK9,PDLIM7,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RHOG,ROGDI,RP1L1,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SIRT2,SKIL,SPAG9,SPTBN1,STX3,TBC1D23,TGFBR1,TIMP2,TOP2B,TRPV4,UBE4B,ULK1,UST,VIM,WASL,WDPCP,WNT5B,YWHAZ,ZFHX3,ZHX2,ZSWIM4,ZSWIM8 |
| GO_NEURON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 1114 | 79 | ABI1,APOD,APP,AUTS2,AVIL,B3GNT2,BAIAP2,BTBD8,CDC42,CRK,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYFIP1,DAB2IP,DBN1,DOK4,EFNA1,EFNB3,ERCC6,FGF13,FRYL,GDI1,GRN,GSK3B,HGF,IFT27,ILK,IQGAP1,ITGA1,ITGB1,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,MDK,NRCAM,NUMB,NYAP1,OPHN1,PALLD,PDLIM7,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RHOG,RP1L1,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SKIL,SPTBN1,STX3,TBC1D23,TOP2B,TRPV4,UBE4B,ULK1,UST,VIM,WASL,WDPCP,YWHAZ,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 955 | 72 | AKAP13,APP,ATP6AP1,AVIL,BAIAP2,CDC42,CRK,CSNK1D,CTDP1,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,DMTN,EFNA1,EFNB3,FGF13,GDI1,GRN,GSK3B,HES6,HGF,IGSF10,ILK,IQGAP1,KANK1,LRP1,LZTS3,MACF1,MAN2A1,MAP1B,MAP2,MAP2K2,MDK,MYADM,MYLK3,NCOA1,NEDD9,NOTCH2,NRCAM,NUMB,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SIRT2,SKIL,SPAG9,TIMP2,TRPV4,UST,VIM,WASHC2C,ZFHX3,ZHX2,ZSWIM4,ZSWIM8 |
| GO_CELL_JUNCTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 293 | 38 | ACTG1,AJM1,APOD,BCAS3,CD151,CDC42,CDH9,CORO2B,CTNNA1,CTNNB1,DMTN,DSP,DST,DUSP3,FBLIM1,GJD3,HRG,ILK,IQGAP1,LAMC1,LIMCH1,LRP1,MACF1,MYO1C,NUMB,OPHN1,PATJ,PEAK1,PIP5K1C,RAB8B,RAPGEF1,RHOA,RHOC,SMAD7,SORBS1,TGFBR1,TRPV4,WDPCP |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 872 | 68 | ABI1,ACSL1,ADAM17,ADCY2,AKAP13,AMBRA1,APP,ATG13,ATP2B4,CACUL1,CCNG1,CCNI,CCNYL2,CD81,CDC42,CEMIP,CHI3L1,CHP1,CRK,CSPG4,CXCR4,DAB2IP,DNAJC3,DSTYK,DUSP3,EFNA1,ERCC6,ERP29,FGF13,FZD8,GMFG,HGF,HIPK3,HMGCR,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,LATS2,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1,MST1R,NEDD9,PIK3IP1,PINK1,PKIG,PPEF2,PRKN,PSEN1,RAPGEF1,RHOA,RUBCN,SH3BP5,SMPD1,SNX6,SNX9,SPAG9,TAOK3,TGFBR1,TRAF6,TSC2 |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 704 | 60 | AACS,ABHD2,ACSL1,ADCY2,AKAP13,AKR1C3,ASS1,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CALCOCO1,CREBRF,CRK,CTNNB1,CTSB,CYFIP1,DAB2,FBXO32,FOXO4,GNAI2,GSK3B,HDAC5,HMGCS1,INPP5K,INSR,KANK1,LATS2,LBH,LEPROT,LPIN1,LPIN2,MAP1B,MSN,MYO1C,NCOA1,NCOA4,NCOR2,NR4A1,NRIP1,PAX8,PCSK9,PLPP1,PRCP,RAB31,RAB8B,RHOA,RHOQ,RNF14,SORBS1,STAT5B,TNFSF4,TRIP4,TSC2,UCN2,WBP2,WDTC1 |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 622 | 56 | AKAP9,ARHGAP21,ARL8B,ATP6AP1,BORCS6,CDC42,CETN2,CHMP1B,CHMP2A,CLN3,COPG1,CSNK1D,CTNNB1,DCTN2,DYNC1H1,ESYT1,ESYT2,EXOC4,EXOC6B,FCER1G,GOLGA2,HMOX1,ITGB1,KIF3C,KIFAP3,MAP1B,MAP2,MARK4,MTM1,MYO1C,NSF,OFD1,PARD3B,PINK1,PLEKHM1,PLEKHM2,PRKN,PSEN1,RAB8B,RHOT1,S100A13,SNAP23,SPAG9,STX3,STX7,STX8,STXBP2,TBC1D23,TPGS1,TRAPPC6A,TTBK2,UBE2B,VPS11,WASL,WIPI1,YWHAZ |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 624 | 56 | AKAP9,ARPC3,ATG13,AUTS2,BAIAP2,BCAS3,C15orf62,CALCOCO2,CDC42,CDC42EP2,CORO1B,CTNNB1,CYFIP1,DCN,DSTN,DYNC1H1,GMFG,GRN,GSK3B,INSR,JDP2,LEPROT,LIMCH1,LRSAM1,MAP1B,MAPK1,MARK4,MIEF2,MOAP1,MSN,MYLK3,MYO1C,NPEPPS,OPTN,PINK1,PIP4K2C,PLXNA3,PRKN,RHOA,RHOC,SDCBP,SH3GLB1,SIRT2,SNX9,SWAP70,TAPT1,TGFBR1,TRPV4,UBE2B,ULK1,VPS11,WASHC2C,WASL,WBP2,YWHAZ,ZNF205 |
| GO_VACUOLAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 141 | 27 | CHMP1B,CHMP2A,DENND3,GRN,IGF2R,LAMP2,LEPROT,LRP1,LYST,MTM1,NCOA4,NDFIP1,PCSK9,PINK1,PRKN,PSAP,RAB7A,RILP,SCARB2,STX8,TMEM50A,TMEM50B,TRAPPC8,UBXN6,VIPAS39,VPS11,ZFYVE16 |
| GO_CHEMICAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1229 | 1207 | 82 | AACS,ACO1,ACOX1,ADCY2,ANXA6,APP,AQP9,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BTBD9,CALB1,CAMK2D,CEMIP,CERT1,CHP1,CLCN3,CLIC4,CLN3,CP,CSMD1,CXCR4,CYBRD1,DCN,ELOVL1,FOXO4,FTH1,FTL,GALR1,GNAI2,GRIN2D,GRINA,GRN,HECTD4,HK1,HMGCR,HMOX1,INPP5K,INSIG1,INSR,ITGAV,ITPR2,LRP1,MAPK1,MCOLN1,MCOLN3,MICU1,MPC2,NCOA4,NDFIP1,PCSK9,PNPLA2,PRCP,PRKN,PSEN1,RAB11FIP5,RAB7A,RCN3,ROGDI,RTN4,SKP1,SLC12A4,SLC12A6,SLC26A4,SLC26A6,SLC31A2,SLC39A13,SLC4A3,SMAD7,SOAT1,SWAP70,TLCD2,TMEM165,TMEM38A,TRPM4,TRPM7,TRPV4,WDTC1 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 1782 | 105 | ACAT1,AGO4,AHNAK,AKAP9,ANXA6,APOC1,ARPC3,ATPAF2,AVIL,BAIAP2,BBS12,BRD2,C15orf62,CAPG,CAPZB,CDA,CDC42,CDC42EP2,CETN2,CHMP2A,CHP1,CORO1B,CSNK1D,CTNNA1,CTNNB1,CYFIP1,CYLD,DAB2IP,DACT1,DBN1,DECR1,DGKD,DMTN,EIF2AK3,EPS15,FBLIM1,FCER1G,FCHO2,FGF13,FNIP1,GLUL,GMFG,GOLGA2,GSK3B,HMGCR,HMOX1,HRG,ILK,INSR,KANK1,KCTD10,KCTD21,KIFAP3,LAMC1,LRRC8A,MAP1B,MAP2,MAP7D3,MCOLN1,MICU1,MIEF2,MSN,MT-ND2,MT-ND5,MT-ND6,MYADM,MYO1C,NSF,OSBPL2,P2RX6,PDE4DIP,PINK1,PPP2R5B,PRKN,RHOA,RHOC,RPS10P5,RPS27L,RTN4,SCUBE3,SH3GLB1,SHARPIN,SIRT2,SKP1,SNAP23,SNX9,SOAT1,SPTBN1,SQSTM1,SRPK3,STING1,TAPBPL,TEAD1,TRAPPC6A,TRIM21,TRPM4,TRPM7,TRPV4,ULK1,UPB1,VPS11,WASHC2C,WASHC3,WASL,WDR19 |
| GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 302 | 38 | BAIAP2,CDC42,CRK,CUL7,CUX1,CYFIP1,DBN1,DMTN,EFNA1,EFNB3,FGF13,GDI1,GSK3B,ILK,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MDK,MYADM,NEDD9,NRCAM,PLXNA3,PSEN1,PTPRD,RHOA,RTN4,SDC2,SEMA4B,SEMA6C,SKIL,UST,WASHC2C,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 337 | 40 | ABR,AKAP13,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,AUTS2,CDC42,CDC42SE1,CDC42SE2,CRK,CYTH1,CYTH2,DAB2IP,EPS8L1,EPS8L2,GDI1,GMIP,ITGB1,KANK1,KCTD10,MADD,NOTCH2,OPHN1,PSD4,RAPGEF1,RHOA,RHOC,RHOG,RHOQ,RHOT1,SHOC2,SQSTM1,TIAM2,TIMP2,TSC2 |
| GO_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1229 | 769 | 62 | AKAP13,APP,ATP6AP1,ATP6AP2,CAVIN3,CD81,CDC42,CHI3L1,CRK,CSPG4,CTNNB1,CXCR4,CYLD,DAB2IP,DACT1,DSTYK,DUSP3,EFNA1,ERCC6,ERP29,FZD8,GNAI2,GPNMB,HGF,HIPK3,HMGCR,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,LBH,LRP1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NOTCH2,PINK1,PJA2,PPEF2,PRKN,PRXL2C,PSAP,PSEN1,PTPRR,RAPGEF1,RRAS,SDCBP,SIRPA,SMPD1,SPAG9,TAOK3,TGFBR1,TIMP2,TRAF6,TRPV4 |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1229 | 604 | 54 | ACVR1,ADAM17,APP,BCAS3,CD151,CEMIP,CHMP2A,CPNE3,CRK,CXCR4,DAB2,DAB2IP,DMTN,DYSF,FAM89B,FOXO4,GNAI2,GPNMB,GRN,HGF,HMOX1,ILK,INSR,IQGAP1,ITGAV,ITGB1,LGALS3,LRP1,MADCAM1,MAP2K2,MAPK1,MDK,MOSPD2,MYADM,MYO1C,NEDD9,NOS3,NUMB,PC,RHOA,RHOC,RRAS2,RTN4,SDCBP,SEMA4B,SEMA6C,SPAG9,STX3,SWAP70,TGFBR1,TMEM102,TNFRSF14,TRPV4,WNT5B |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1229 | 1559 | 95 | ABR,ABRAXAS1,APOD,APP,ATP2B4,CALCRL,CAMK2D,CD109,CD81,CDC42,CDK19,CORO2B,CRK,CTNNB1,CTSB,CXCR4,CYLD,DAB2IP,DACT1,DMTN,DNAJC3,DNASE1,DUSP3,EIF2AK3,ERCC6,ERP29,FAP,FBLN5,FCER1G,FNDC4,FZD8,GRAMD4,GRINA,GRN,GSK3B,HGF,HIPK3,HMGCR,HRG,IGBP1,IL17RA,INSIG1,JAK1,KANK1,LRP1,LRSAM1,LY96,MAP2K2,MAP3K10,MAPK1,MAPKAPK2,MDK,MEAK7,MICA,MICU1,NDFIP1,NLRP10,NOS3,NUAK1,OPTN,OS9,OSMR,PINK1,PJA2,PLA2R1,PPEF2,PRKN,PROS1,PSAP,PTTG1IP,RAPGEF1,RFTN1,RTN4,SDCBP,SERINC3,SHARPIN,SIRPA,SIRT2,SKIL,SKP1,SLAMF6,SPAG9,STAT5B,STING1,TANK,TAOK3,TBC1D23,TNFSF4,TRAF6,TRPV4,UBXN1,VNN1,WDFY1,YPEL3,ZNF277 |
| GO_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 402 | 43 | ABR,ALS2CL,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ASAP2,BCAS3,CDC42EP2,CHM,CRK,DAB2IP,GDI1,GIT2,GMIP,GSK3B,IQGAP1,ITGB1,NEDD9,OPHN1,RABGAP1,RABGAP1L,RAPGEF1,RASAL2,RGP1,RHOG,RP2,SNX9,STXBP5,TBC1D12,TBC1D17,TBC1D19,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,TIAM2,TSC2,USP6 |
| GO_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1229 | 695 | 58 | APOD,ARHGDIG,ASS1,BCAS3,CD164,CD276,CD81,CDC42,CORO2B,CRK,CXCR4,CYLD,CYTH1,DMTN,DUSP3,DYSF,EFNA1,EFNB3,GPNMB,GSK3B,HRG,ILK,IQGAP1,ITGAV,KANK1,KIFAP3,LGALS3,LIMCH1,LRP1,MACF1,MAP3K8,MDK,MYADM,NDFIP1,NEDD9,NFAT5,NID1,NUAK1,PEAK1,PLXNA3,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,STX3,SWAP70,TMEM102,TNFRSF14,TNFSF4,TRAF6,TRPV4,TWSG1,VNN1,WASHC2C,WDPCP,ZFHX3,ZMIZ1 |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1229 | 1174 | 79 | AKAP9,ANXA4,APLP2,APOC1,APP,ATP2B4,BCAS3,CAMK2D,CD109,CDC42SE1,CHP1,CLN3,CST3,CSTB,CYLD,DAB2,DAB2IP,DACT1,DHCR24,DNAJB2,DNAJC3,DUSP3,DYSF,FNIP1,FURIN,GALR1,GLIS2,GMFG,GMIP,GNAI2,GOLGA2,GSK3B,HGF,HIPK3,HMGCR,HMOX1,HRG,IGBP1,ILK,INPP5K,IQGAP1,KCNE1,KDM5A,LATS2,LGALS3,LRP1,MAP2,MAP3K10,MICAL1,NDFIP1,NOS3,NQO1,PCSK9,PIK3IP1,PKIG,PLA2R1,PPP1R12C,PRDX5,PRKN,PROS1,PSEN1,RAB9A,RUBCN,SERPINB1,SERPINB6,SH3BP5,SMAD7,SMPD1,SNX6,TAOK3,TIMP2,TMBIM1,TNFSF4,TRIM21,TSC2,TTBK2,UBXN1,WDTC1,ZFYVE1 |
| GO_GROWTH | 0.0e+00 | 0.0e+00 | 1229 | 990 | 71 | ADAM17,AKAP13,ANXA6,APBA2,APOD,APP,ARID5B,AUTS2,CAMK2D,CD81,CDA,CDC42,CLIC4,COL6A1,COL6A2,CPQ,CTDP1,CTNNB1,CXCR4,CYFIP1,DAB2IP,DBN1,DNAJB2,DYSF,ERCC6,EVC,FBLN5,FGF13,GDI1,GNAS,GSK3B,HRG,ILK,ING4,INSR,IQGAP1,ITGB1,KCTD21,KDM5B,KIAA1109,KLF2,LATS2,LRP1,MACF1,MAP1B,MAP2,MAPK1,MATN3,MDK,MTM1,NEDD9,NOTCH2,NRCAM,PLXNA3,PRKN,PSAP,RFTN1,RHOA,RTN4,SAV1,SDCBP,SEMA4B,SEMA6C,SERTAD3,SGPL1,STAT5B,TGFBR1,THBS3,ULK1,WDTC1,ZMIZ1 |
| GO_ENDOSOMAL_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 228 | 32 | BTBD8,CHMP1B,CHMP2A,CLTCL1,CMTM6,DENND10,EPS15,ERC1,HEATR5B,LEPROT,LYST,MVB12B,PRKN,RAB7A,RAB9A,RGP1,RILP,SNX33,SNX6,SNX8,SNX9,SPAG9,SQSTM1,TBC1D17,TBC1D23,TMEM50A,TMEM50B,TOM1,UBXN6,VPS26C,WASHC2C,ZFYVE16 |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1229 | 974 | 70 | AKAP13,APP,ARHGEF6,ATP6AP1,ATP6AP2,CAVIN3,CD81,CDC42,CHI3L1,CRK,CSF2RA,CSPG4,CTNNB1,CXCR4,CYLD,DAB2IP,DACT1,DSTYK,DUSP3,EFNA1,ERCC6,ERP29,FGF13,FZD8,GNAI2,GPNMB,HGF,HIPK3,HMGCR,IGBP1,ILK,INPP5K,INSR,IQGAP1,ITGA1,ITGAV,JAK1,LAMTOR3,LBH,LRP1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NOTCH2,PINK1,PJA2,PPEF2,PRKN,PRXL2C,PSAP,PSEN1,PTPRR,RAPGEF1,RASAL2,RRAS,SDCBP,SIRPA,SKP1,SMPD1,SPAG9,SPTBN1,TAOK3,TGFBR1,TIMP2,TRAF6,TRPV4 |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 752 | 60 | ABRAXAS1,AKAP9,APP,ARHGAP21,ARL8A,ARL8B,BBS12,BCAS3,CCSER2,CDC42,CDK2AP2,CEP126,CEP295NL,CETN2,CHMP1B,CHMP2A,CHP1,CLN3,COPG1,CSNK1D,CTNNB1,CUL7,CYLD,DCTN2,DST,DYNC1H1,FGF13,GABARAP,GOLGA2,GOLGA8N,GSK3B,IFT27,IGBP1,ITGB1,KIAA0556,KIF3C,KIFAP3,KIZ,LCA5,MACF1,MAP1B,MAP2,MAP7D3,MARK4,NCKAP5L,OFD1,PARD3B,RHOA,RHOT1,RP1L1,RSPH9,SIK3,SPEF1,TPGS1,TRIM54,TRPV4,TTBK2,TTLL3,UBE2B,WDR19 |
| GO_CELL_JUNCTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 244 | 33 | ACTG1,APOD,BCAS3,CD151,CDC42,CDH9,CORO2B,CTNNA1,CTNNB1,DMTN,DST,DUSP3,FBLIM1,GJD3,HRG,ILK,IQGAP1,LAMC1,LIMCH1,LRP1,MACF1,MYO1C,OPHN1,PATJ,PEAK1,PIP5K1C,RAPGEF1,RHOA,RHOC,SMAD7,SORBS1,TRPV4,WDPCP |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1146 | 77 | ABI1,ACSL1,ACVR1,ADAM17,ADCY2,AKAP13,AKAP9,AMBRA1,APP,ARNT,ATG13,ATP2B4,ATP6AP1,CACUL1,CAVIN3,CCNYL2,CD81,CDC42,CEMIP,CHI3L1,CREBL2,CRK,CSNK1D,CSPG4,CTNNB1,CXCR4,DAB2,DAB2IP,DSTYK,EFNA1,ERCC6,ERP29,FGF13,FNIP1,FZD8,GNAI2,GPNMB,HGF,HMGCR,ILK,INSR,IQGAP1,ITGA1,LAMTOR3,LIMCH1,LRP1,LRRK1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NEDD9,NOS3,NOTCH2,PINK1,PJA2,PRR5L,PRXL2C,PSAP,PSEN1,RAPGEF1,RHOA,SDCBP,SMPD1,SNX9,SPAG9,SQSTM1,TAOK3,TGFBR1,TIMP2,TNFRSF14,TRAF6,TRPV4,TWSG1 |
| GO_CELL_SUBSTRATE_ADHESION | 0.0e+00 | 0.0e+00 | 1229 | 348 | 39 | APOD,BCAS3,CD63,CDC42,COL13A1,CORO2B,CRK,CTNNB1,DMTN,DUSP3,EFNA1,FBLN5,GSK3B,HRG,ILK,IQGAP1,ITGA1,ITGA7,ITGAV,ITGB1,KANK1,LAMC1,LIMCH1,LRP1,MACF1,MADCAM1,MDK,MEGF9,MYADM,NEDD9,NID1,PEAK1,RHOA,SGCE,SORBS1,THBS3,TRPM7,WASHC2C,WDPCP |
| GO_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 477 | 46 | ABR,ALS2CL,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ASAP2,BCAS3,CDC42EP2,CDC42SE1,CHM,CRK,DAB2IP,GDI1,GIT2,GMIP,GSK3B,IQGAP1,ITGB1,NEDD9,OPHN1,PLXNA3,RABGAP1,RABGAP1L,RAPGEF1,RASAL2,RGP1,RHOG,RP2,SNX9,STXBP5,TBC1D12,TBC1D17,TBC1D19,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,TIAM2,TRAPPC6A,TSC2,USP6 |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1428 | 88 | AAMDC,ACVR1,ARNT,ATP6AP1,AVIL,BAIAP2,CDC42,CHI3L1,CORO1B,CREBL2,CRK,CSNK1D,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,CYLD,DAB2,DAB2IP,DBN1,DCN,DMTN,GDI1,GNAS,GRN,HGF,HMGCR,HMOX1,ILK,INSR,IQGAP1,ITGB1,JAK1,KDM5B,LBH,LRP1,LTBP3,MACF1,MAN2A1,MAP1B,MAP2K2,MAPK1,MDK,MIEF2,MST1,MTM1,MYADM,MYLK3,NCOA1,NEDD9,NOS3,NOTCH2,NRCAM,NUMB,PAX8,PDLIM7,PINK1,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RRAS,RTN4,SAV1,SCARB2,SCX,SDCBP,SIRT2,SKIL,SPAG9,STAT5B,TAPT1,TGFBR1,TIMP2,TNFSF4,TRAF6,TRPM4,VNN1,WNT5B,YPEL3,ZMIZ1 |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1229 | 1765 | 101 | ABR,ACTG1,ACVR1,ADAM17,APOD,APP,ASS1,C1S,CALCOCO2,CALCRL,CAMK2D,CAMLG,CD81,CDC42,CDC42EP2,CDK19,CHI3L1,CRK,CST3,CTSB,CXCR4,CYLD,DAB2IP,DNAJC3,DNASE1,ERCC6,EXOC1,FCER1G,FNDC4,GBP2,GRAMD4,GRN,HDAC5,HGF,HK1,HMOX1,HRG,HYAL3,IFI35,IFIT3,IGHV3-74,IL17RA,IRF9,ITGB1,JAK1,LGALS3,LRP1,LRSAM1,LY96,LYST,MAPKAPK2,MDK,MICA,MICU1,MST1R,MYLK3,MYO1C,NCF2,NDFIP1,NLRP10,NOTCH2,OPTN,OSMR,PJA2,PRCP,PRDX5,PSEN1,RAB23,RAB43,RFTN1,RTN4,SERINC3,SERINC5,SHARPIN,SHFL,SIRPA,SIRPB1,SIRT2,SKP1,SLAMF6,SLC26A6,SNAP23,SPON2,STAT2,STAT5B,STING1,STX8,STXBP2,TANK,TBC1D23,TBKBP1,TNFRSF14,TNFSF4,TOLLIP,TRAF6,TRIM21,TRIM35,TRPV4,VIM,VNN1,WDFY1 |
| GO_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 659 | 55 | APP,AVIL,BAIAP2,CRK,CSNK1D,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,EFNA1,EFNB3,FGF13,GDI1,GRN,GSK3B,HGF,ILK,IQGAP1,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MDK,NCOA1,NRCAM,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SKIL,SPAG9,TIMP2,TRPV4,UST,VIM,ZFHX3,ZHX2,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 767 | 60 | AACS,ANXA4,APOD,ATG13,ATP13A2,BCAS3,CD81,CDC42,CEMIP,CHP1,CORO2B,CTSD,CYP51A1,DMTN,ERP29,EXOC1,FRMD4A,FRMD8,GDI1,GLUL,GSK3B,HK1,HMGCR,IL17RA,INPP5K,INSIG1,ITPR2,KCNE1,LEPROT,LRP1,MAPK1,MDK,MIEF2,MPC2,MYO1C,NDFIP1,NLRP10,NPEPPS,NUCB1,NUMB,OPHN1,OS9,PINK1,PKIG,PRKN,PRR5L,PSEN1,RAB11FIP5,RAB23,RHBDF1,SERPINB1,SH3GLB1,SPTBN1,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4,VPS11,YWHAZ |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 1160 | 77 | AHNAK,AKAP9,ANO10,ANXA6,APP,AQP9,ATP10D,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BEST1,CAMK2D,CAPN1,CD63,CEMIP,CHP1,CHRNB1,CLCN3,CLCN6,CLCN7,CLIC4,CLN8,COX6A1,COX6C,DYSF,GJD3,GRIN2D,HCN3,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,LRRC8A,MCOLN1,MCOLN3,MICU1,MPC2,MT-ATP6,MT-ATP8,NIPA1,OSTM1,P2RX6,PCSK9,PINK1,PSEN1,SESTD1,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC17A5,SLC22A4,SLC26A11,SLC26A4,SLC26A6,SLC2A6,SLC31A2,SLC37A1,SLC38A2,SLC38A7,SLC39A13,SLC41A2,SLC43A2,SLC4A3,TMCO3,TMEM38A,TMEM63B,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 620 | 53 | ATP2B4,CAMLG,CD109,CHP1,CRTAP,CTDSP2,CTNNB1,CYLD,DAB2IP,DACT1,DMTN,DNAJC3,DUSP3,DYSF,EFNA1,GMFG,GNAI2,GSK3B,HGF,HIPK3,HMGCR,IGBP1,ILK,INPP5K,KDM5A,LATS2,LGALS3,LRRK1,MICAL1,MYADM,PINK1,PKIG,PPEF2,PRKN,PRR5L,PSEN1,PTPRR,RAPGEF1,SH3BP5,SIRPA,SIRT2,SMAD7,SMPD1,SNX6,SQSTM1,SWAP70,TAOK3,TINF2,TMEM59,TRIM21,TSC2,UBE2B,UBXN1 |
| GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 504 | 47 | AVIL,BAIAP2,CRK,CUL7,CUX1,CXCR4,CYFIP1,DAB2IP,DBN1,EFNA1,EFNB3,FGF13,GDI1,GRN,GSK3B,HGF,ILK,IQGAP1,KANK1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MDK,NRCAM,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SKIL,TRPV4,UST,VIM,ZSWIM4,ZSWIM8 |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 710 | 57 | ACAT2,ACOT8,ACSL1,ACSS2,AKR1C3,APOC1,CDIPT,CDS2,CERT1,CLN8,CPNE3,CREBL2,CYB5R3,CYP51A1,CYP8B1,DHCR24,EBP,ELOVL1,ERG28,FDFT1,FDPS,GK,HMGCR,HMGCS1,HSD17B11,HSD17B2,IDH1,IDI1,INPP5K,INSIG1,LPIN1,LPIN2,LSS,MBOAT2,MSMO1,MTM1,MTMR3,NSDHL,OSBPL1A,OSBPL2,PI4K2A,PIGG,PIP4K2C,PIP5K1C,PITPNM1,PLPP1,SAMD8,SC5D,SCD,SERINC1,SERINC5,SGPL1,SMPD1,SORBS1,SPTLC1,STARD4,WDTC1 |
| GO_RESPONSE_TO_GROWTH_FACTOR | 0.0e+00 | 0.0e+00 | 1229 | 732 | 58 | ACVR1,ADAM17,ADAMTSL2,APP,ARNT,ARPC3,BAIAP2,CD109,CD63,CORO1B,CPNE3,CRK,CTNNB1,CYFIP1,DAB2,DAB2IP,DCN,DSTYK,DUSP3,EEF2,FAM89B,FNDC4,FURIN,GALNT3,GLG1,HGF,HRG,ILK,INPP5K,INSR,IQGAP1,KDM5B,LTBP3,MAP1B,MAPK1,MAPKAPK2,MYO1C,NOTCH2,NR4A1,PPP2R5B,RAPGEF1,RHOA,SCX,SDCBP,SHOC2,SIRT2,SKIL,SMAD7,SMAD9,SNX6,STAT5B,TBC1D7,TGFBR1,TWSG1,USP9Y,VASN,ZFHX3,ZFYVE16 |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1229 | 1864 | 104 | ABRAXAS1,ACVR1,ADAM17,AGO4,AKAP9,ANXA11,APP,ARAP1,ARL8A,ARL8B,ATP2B4,CACUL1,CCNDBP1,CCNG1,CCNI,CCNYL2,CDC42,CDK19,CDK2AP2,CEP126,CEP295NL,CETN2,CHMP1B,CHMP2A,CLTCL1,CREBL2,CSNK1D,CTCFL,CTDP1,CTDSP2,CTNNB1,CUL7,CYLD,DAB2IP,DACT1,DCTN2,DHCR24,DUSP3,DYNC1H1,DYNLT3,ERCC6,FAP,FBXL12,FOXO4,GNAI2,GOLGA2,GOLGA8N,GPNMB,HBP1,HECA,HGF,ILK,ING4,INSR,IQGAP1,ITGB1,KIZ,KLF11,KLHDC8B,LAMTOR3,LATS2,LPIN1,MADD,MAP3K8,MAPK1,MARK4,NEDD9,NEK11,NOTCH2,NR4A1,OFD1,OPTN,PARD3B,POLD4,PPP2R5B,RABGAP1,REC8,RHOA,RHOC,RPS27L,RRAGC,SDCBP,SH3GLB1,SIRT2,SKIL,SKP1,SNX33,SNX9,SPTBN1,STAT5B,SVIL,TAOK3,TGFBR1,TIMP2,TOP2B,TP53INP1,TRIM21,TRIM35,TSC2,UBE2B,UBR2,WASL,ZFHX3,ZFYVE26 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 823 | 62 | AKAP9,ANXA4,APLP2,APOC1,APP,ATP2B4,BCAS3,CD109,CDC42SE1,CHP1,CLN3,CST3,CSTB,DAB2IP,DHCR24,DNAJC3,DUSP3,FNIP1,FURIN,GALR1,GMFG,GMIP,GNAI2,GSK3B,HGF,HIPK3,HMGCR,HRG,IGBP1,ILK,INPP5K,IQGAP1,KDM5A,LATS2,LGALS3,LRP1,MAP2,MICAL1,NOS3,NQO1,PIK3IP1,PKIG,PLA2R1,PPP1R12C,PRDX5,PRKN,PROS1,PSEN1,RUBCN,SERPINB1,SERPINB6,SH3BP5,SMAD7,SMPD1,SNX6,TAOK3,TIMP2,TMBIM1,TSC2,UBXN1,WDTC1,ZFYVE1 |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 567 | 50 | AKAP9,ARAP1,ARHGEF6,ATP6V1D,AUTS2,AVIL,BCAS3,C15orf62,CAPZB,CDC42,CDC42EP2,CEP126,CETN2,CFAP410,CSNK1D,CYFIP1,CYLD,DCTN2,DMTN,DYNC1H1,EPS8L1,EPS8L2,HRG,IFT27,INPP5K,ITGB1,KANK1,KIF3C,KIFAP3,MARK4,OFD1,OPHN1,PLEKHM1,PMP22,RAB23,RHOG,RHOQ,RP1L1,RSPH9,SDCBP,TAPT1,TBC1D7,TGFBR1,TPGS1,TTBK2,TTLL3,UBE2B,WASL,WDPCP,WDR19 |
| GO_PHOSPHOLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 432 | 43 | AMBRA1,APOC1,CD81,CDC42,CDIPT,CDS2,CLN8,CPNE3,DAB2IP,FDFT1,FDPS,GPCPD1,HADHA,HADHB,HMGCS1,IDH1,IDI1,INPP5K,IP6K1,LPIN1,LPIN2,MBOAT2,MTM1,MTMR3,PCSK9,PI4K2A,PIGG,PIK3IP1,PIP4K2C,PIP5K1C,PITPNM1,PLA2G15,PLPP1,PNPLA6,RUBCN,SAMD8,SERINC1,SERINC2,SERINC3,SERINC5,SMPD1,SPTLC1,TMEM150A |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 326 | 37 | ATG13,BCAS3,CD81,CDC42,CEMIP,CHP1,CYLD,EIF2AK3,FCER1G,GLIS2,GSK3B,IQGAP1,ITGB1,LEPROT,LGALS3,LRP1,MAPK1,MARK4,MEAK7,MIEF2,MSN,MYO1C,NPEPPS,PINK1,PRKN,PRR5L,PSEN1,RHOG,RTN4,SH3GLB1,SNX33,SORBS1,SPTBN1,SQSTM1,STX3,VPS11,YWHAZ |
| GO_DEVELOPMENTAL_GROWTH | 0.0e+00 | 0.0e+00 | 1229 | 677 | 55 | AKAP13,ANXA6,APBA2,APOD,APP,ARID5B,AUTS2,CD81,CLIC4,COL6A1,COL6A2,CPQ,CTDP1,CTNNB1,CXCR4,CYFIP1,DBN1,DYSF,ERCC6,EVC,FGF13,GDI1,GNAS,GSK3B,ILK,INSR,IQGAP1,ITGB1,KDM5B,KLF2,LATS2,LRP1,MACF1,MAP1B,MAP2,MAPK1,MATN3,MDK,MTM1,NOTCH2,NRCAM,PLXNA3,PRKN,PSAP,RTN4,SAV1,SEMA4B,SEMA6C,SGPL1,STAT5B,TGFBR1,THBS3,ULK1,WDTC1,ZMIZ1 |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 767 | 59 | ABR,ALS2CL,APP,ARAP1,ARHGAP10,ARHGAP21,ARHGAP23,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,ASAP2,BCAS3,CDC42EP2,CHM,CRK,CTSD,DAB2IP,DNAJB2,EFNA1,EIF2AK3,GABARAPL2,GDI1,GIT2,GMIP,GRAMD4,GRN,GSK3B,IQGAP1,ITGA1,ITGB1,NEDD9,OPHN1,PINK1,PSAP,RABGAP1,RABGAP1L,RAPGEF1,RASAL2,RCN3,RGP1,RHOA,RHOC,RHOG,RP2,RPS27L,SNX9,STXBP5,TANK,TBC1D12,TBC1D17,TBC1D19,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,TIAM2,TSC2,USP6 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1164 | 76 | AACS,ACAN,ACAT1,ACAT2,ACO1,ACOT8,ACOX1,ACSL1,ACSS2,ADH5,AKR1C3,ALDH6A1,ALKBH7,APOC1,APP,ARNT,ASS1,ATP2B4,B3GNT2,CEMIP,CHP1,CHPF,CLN3,CSPG4,CTNS,CYB5R3,CYP2W1,CYP8B1,DCN,DECR1,EHHADH,ELOVL1,FN3K,GALNS,GLUL,GNS,HADHA,HADHB,HGF,HK1,HYAL3,IDH1,INSIG1,INSR,LPIN1,LPIN2,MAPKAPK2,MPC2,MSMO1,NAGK,NOS3,NQO1,OSBPL1A,OSBPL2,PC,PEPD,PGM1,PGM2L1,PHYH,PLA2G15,PLOD2,PRXL2C,PSEN1,SCD,SCPEP1,SERINC3,SERINC5,SGPL1,SLC2A6,STARD4,STAT5B,SULT1C2,UPB1,UST,VNN1,WDTC1 |
| GO_TUBE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 1122 | 74 | ACAT1,ACVR1,ADAMTSL2,AMBRA1,APOD,ASS1,ATP6AP2,BCAS3,CALB1,CALCRL,CDC42,CHI3L1,CIC,CLIC4,CSPG4,CTNNB1,CUL7,CXCR4,DAB2IP,DACT1,DCN,DYSF,EFNA1,EIF2AK3,ESM1,FAP,FOXL1,FOXO4,FZD8,GLUL,GPNMB,GPR161,GRN,HDAC5,HECA,HGF,HIF3A,HMOX1,HRG,HTATIP2,ILK,ITGAV,ITGB1,JAK1,KDM5B,KLF2,LRP1,LTBP3,MAN1A2,MAN2A1,MAP2K2,MAPK1,MDK,MFGE8,NOS3,NOTCH2,NR4A1,NRCAM,PAX8,PRCP,PSEN1,RCN3,REC8,RHOA,RRAS,SAV1,SGPL1,SLC12A6,SMAD7,TGFBR1,TRAF6,TSC2,WDR19,ZMIZ1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1988 | 107 | ACVR1,APP,ARID5B,ARMCX3,ARNT,ARNT2,ASS1,ATP1B4,AUTS2,BCAS3,CALCOCO1,CAMTA2,CD276,CD81,CDC42,CHP1,CREBL2,CREBRF,CTCFL,CTNNB1,DAB2,DAB2IP,DCAF6,DCN,DNAJC3,EAPP,EEF2,EGR4,EIF2AK3,ERCC6,FANK1,FOSL2,FOXO4,GALR1,GLIS2,GLMP,GOLGA2,HCFC2,HDAC5,HGF,HIF3A,HMOX1,HTATIP2,ILK,ING4,INPP5K,INSIG1,INSR,KDM5A,KLF12,KLF13,KLF2,KLF6,KMT2C,LBH,LITAF,LPIN1,LPIN2,MAP2K2,MAPK1,MAPKAPK2,MDK,MOSPD1,NCOA1,NCOA4,NFAT5,NOS3,NR4A1,NRIP1,PAOX,PAX8,PINK1,PPP2R5B,PRKN,PSEN1,RHOA,RHOG,RHOQ,RNF14,RPS27L,SCX,SERTAD3,SIRT2,SMAD7,SMAD9,SOAT1,SORBS1,SQSTM1,STARD4,STAT2,STAT5B,STING1,TEAD1,TGFBR1,TP53INP1,TP53INP2,TRAF6,TRIP4,VIM,WASL,WBP2,ZFHX2,ZFHX3,ZMIZ1,ZNF205,ZNF281,ZXDC |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 526 | 47 | AKAP9,ARAP1,ARPC3,ATP13A2,AUTS2,BAIAP2,BCAS3,C15orf62,CDC42,CDC42EP2,CHMP2A,CORO1B,CYFIP1,DYNC1H1,EPS8L1,EPS8L2,FNIP1,GMFG,GSK3B,HRG,IQGAP1,LIMCH1,LRSAM1,MAP1B,MARK4,MIEF2,MSN,MYLK3,MYO1C,PINK1,PIP4K2C,PLEKHM1,PPP2R5B,PTPRD,RAB7A,RHOA,RHOC,RHOQ,SDCBP,SH3GLB1,SNX9,SWAP70,TAPT1,TGFBR1,ULK1,WASHC2C,WASL |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1229 | 737 | 57 | ABR,AKAP13,AKR1C3,ARHGEF12,ARHGEF6,CAMK2D,CDC42,CDK19,CTNNA1,CTNNB1,CTSD,CYLD,DAB2IP,DEDD2,EIF2AK3,FANK1,FAP,FNIP1,GRAMD4,GRN,GSK3B,HEBP2,HMGCR,HMOX1,HRG,IGF2R,ING4,ITGA1,ITGB1,KLF11,LATS2,LRP1,MAP3K10,MARK4,MOAP1,NCOA1,NOTCH2,NQO1,PCSK9,PHLDA3,PINK1,PSEN1,RHOA,RPS27L,SAV1,SERINC3,SIRT2,SKIL,SMPD1,SQSTM1,TGFBR1,TIAM2,TP53INP1,TRAF6,TRIM35,YWHAZ,ZNF205 |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 528 | 47 | ALKBH7,AMBRA1,ATG13,ATG2B,ATP13A2,CERT1,CLN8,DCN,FNIP1,FUNDC2,GABARAP,GABARAPL2,GSK3B,HEBP2,HGF,LEPROT,MAN2A1,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MIEF2,MOAP1,MT-ATP6,MT-ATP8,MT-ND2,MT-ND5,MT-ND6,MTM1,NOS3,NPEPPS,OPTN,PINK1,PRKN,RAB32,RHOT1,SH3GLB1,SHARPIN,SQSTM1,STAT2,TMEM102,TSC2,VAT1,VPS11,WDR45,WIPI1,YWHAZ,ZNF205 |
| GO_ACTIN_FILAMENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 393 | 40 | ABI1,ARAP1,ARPC3,AVIL,BAIAP2,C15orf62,CAP1,CAPG,CAPZB,CDC42,CDC42EP2,CORO1B,CORO2B,CYFIP1,DBN1,DMTN,DSTN,ERMN,GMFG,INPP5K,KANK1,LIMCH1,MICAL1,MYADM,MYO1C,NEDD9,PRKN,RHOA,RHOC,RHOG,RHOQ,SNX9,SORBS1,SPTBN1,SWAP70,TGFBR1,TRPV4,WASHC2C,WASHC3,WASL |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 928 | 65 | APP,AVIL,BAIAP2,CRK,CSNK1D,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,EFNA1,EFNB3,EIF2AK3,FGF13,GDI1,GPR161,GRN,GSK3B,HES6,HGF,IGSF10,ILK,IQGAP1,KANK1,LRP1,LZTS3,MACF1,MAN2A1,MAP1B,MAP2,MAP2K2,MDK,NCOA1,NRCAM,NUMB,PLXNA3,PMP22,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,RTN4,SCARB2,SDC2,SEMA4B,SEMA6C,SIRT2,SKIL,SPAG9,TIMP2,TRPV4,UST,VIM,YWHAZ,ZFHX3,ZHX2,ZSWIM4,ZSWIM8 |
| GO_METAL_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 906 | 64 | AHNAK,AKAP9,ANXA6,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BEST1,CALCRL,CAMK2D,CD63,CEMIP,CHP1,CP,CTNNB1,CXCR4,DYSF,FGF13,FTH1,FTL,GNAI2,GRIN2D,HCN3,HRG,INPP5K,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,LGALS3,MAGED2,MCOLN1,MCOLN3,MICU1,NDFIP1,NIPA1,NOS3,NSF,PCSK9,PSEN1,REP15,RHOA,SARAF,SESTD1,SLC10A6,SLC12A4,SLC12A6,SLC13A1,SLC22A4,SLC31A2,SLC38A2,SLC38A7,SLC39A13,SLC41A2,TMEM165,TMEM38A,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_STEROL_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 168 | 26 | ACAT2,APOBR,APOC1,APP,CLN8,CYB5R3,CYP51A1,CYP8B1,DHCR24,EBP,ERG28,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,INSIG1,LSS,MSMO1,NSDHL,OSBPL1A,PCSK9,SC5D,SCD,SMPD1,SOAT1 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1229 | 1716 | 96 | ABI1,ADAM17,AKR1C3,AMBRA1,APOD,APP,ARNT,ARNT2,CACUL1,CALCRL,CAPN1,CAPNS1,CD109,CD164,CD276,CD81,CDC42,CTNNA1,CTNNB1,DAB2IP,DHCR24,DNAJB2,DYSF,EAPP,EGR4,EPS15,ESM1,FAP,FOSL2,FOXO4,FRK,FTH1,GLUL,GNAI2,GPNMB,GRN,HMGCR,HMOX1,HRG,IFIT3,IGFBP6,ILK,ING4,INSR,ITGA1,ITGAV,ITGB1,KDM5B,KIFAP3,KLF11,KLF13,LAMC1,LBH,LGALS3,LTBP3,MAPK1,MDK,MEAK7,MST1,MST1R,MXD4,NDFIP1,NOS3,NOTCH2,NR4A1,NUAK1,OSMR,PLPP1,PMP22,RAPGEF1,RHOA,RHOG,ROGDI,RTN4,S100A11,S100A13,SAV1,SCX,SDCBP,SIRT2,STAT2,STAT5B,STX3,TGFBR1,TIMP2,TINF2,TMEM127,TNFRSF14,TNFSF4,TP53INP1,TRAF6,TRPM4,TSC2,TSPAN31,TWSG1,ZMIZ1 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1229 | 1665 | 94 | AACS,ABR,AGO4,AKAP9,APBA2,APP,ATP6AP2,BAIAP2,CALB1,CALCOCO1,CDC42,CHRNB1,CSNK1D,CTNNB1,CYFIP1,CYLD,DAB2,DAB2IP,DACT1,DBN1,DTNA,EFNA1,EFNB3,EXOC4,FGF13,FOXL1,FRAT1,FZD8,GABARAP,GALR1,GLUL,GNAI2,GNAS,GPNMB,GRIN2D,GSK3B,HBP1,HGF,HMGCR,IGFBP6,ILK,ITGB1,ITPR2,KANK1,KDM5B,LATS2,LMBR1L,LRP1,LRRK1,MACF1,MAP1B,MAPK1,MDK,MPC2,MPZL1,NID1,NQO1,OPHN1,P2RX6,PAX8,PCDHB10,PCDHB13,PCDHB14,PCDHB9,PINK1,PIP5K1C,PMP22,PPM1N,PRKN,PSEN1,PTPRD,RAB11FIP5,RAB8B,RAPGEF1,RHOA,RHOT1,RNF146,SDCBP,SKP1,SLC12A4,SLC12A6,SNAP23,SQSTM1,STX3,TMEM88,TOLLIP,TPGS1,TPRG1L,TRPM4,TRPV4,TSC2,TSHZ3,UBE2B,WNT5B |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 542 | 47 | ATP2B4,CASTOR2,CASTOR3,CAVIN3,CHP1,CYLD,DAB2IP,DACT1,DUSP3,EFNA1,FNIP1,GNAI2,GRINA,GSK3B,HIPK3,HMGCR,IGBP1,INPP5K,ITGB1,KANK1,KCTD10,LITAF,MTM1,MYADM,OPTN,PHLDA3,PIK3IP1,PINK1,PPEF2,PPM1N,PPP2R5B,PRKN,PTPRR,PTTG1IP,RAPGEF1,RHOA,SIRPA,SMPD1,TANK,TAOK3,TBC1D7,TIMP2,TMEM127,TSC2,UBE2B,UBR2,VNN1 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1229 | 625 | 51 | CD81,CEMIP,CHM,CHP1,DAB2,DMTN,EXOC4,FCER1G,FCHO2,FGF13,GDI1,INPP5K,ITGB1,KCNE1,LGALS3,LRP1,MACF1,MADCAM1,MIEF2,MOAP1,MYADM,MYO1C,NSF,NUMB,OPTN,PRKN,RAB31,RAB32,RAB8B,RFTN1,RHOG,RHOQ,SDCBP,SH3GLB1,SORBS1,SPTBN1,SQSTM1,SRP14,STX3,STX7,STX8,TMBIM1,TMEM150A,TMEM59,TMEM88,TSPAN14,WDR19,YWHAZ,ZDHHC1,ZDHHC2,ZDHHC7 |
| GO_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1229 | 735 | 56 | APLP2,APP,ATP13A2,CAMLG,CD109,CLN3,CLN8,CSNK1D,CST3,CSTB,CTSD,DAB2,DAB2IP,DHCR24,DNAJB2,EFNA1,EIF2AK3,FNIP1,FURIN,GABARAPL2,GLG1,GRAMD4,GRN,GSK3B,HGF,HRG,IGBP1,LRP1,MICAL1,MTM1,NRDC,OPHN1,OS9,PINK1,PRDX5,PRKN,PROS1,PSEN1,RCN3,RHBDF1,RHOA,RNF14,RPS27L,SDCBP,SERPINB1,SERPINB6,SIRT2,SMAD7,SNX33,SNX9,TANK,TIMP2,TMEM59,TRIM21,UBXN1,ZER1 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1229 | 1258 | 78 | ABI1,ACVR1,ADAM17,ADH5,AKAP9,APP,ARNT,ATP13A2,ATP2B4,AUTS2,CAMK2D,CD81,CEMIP,CHI3L1,CREBL2,CRTAP,CSNK1D,CSPG4,CTCFL,CTNNB1,DCN,DMTN,DSTYK,EFNA1,EIF2AK3,ERCC6,FKBP9,FNIP1,FRK,GALNT3,GSK3B,HGF,HIPK3,HRG,ILK,ING4,INPP5K,INSR,IQGAP1,JAK1,KANSL3,KMT2C,LATS2,LRRK1,MAP2K2,MAP3K10,MAPK1,MAPKAPK2,MST1R,NCOA1,NEDD9,P4HA3,PEAK1,PINK1,PLOD2,PPEF2,PPP2R5B,PSEN1,SH3BP5,SIRT2,SMAD7,SNX6,STK38L,TGFBR1,TMEM102,TNFRSF14,TOLLIP,TPGS1,TRPM4,TTBK2,TTLL3,ULK1,VIPAS39,WBP2,ZDHHC1,ZDHHC2,ZDHHC7,ZMIZ1 |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 1567 | 90 | ABR,ACTG1,ADAM17,ADH5,APP,ASS1,BAIAP2,C1S,CALCOCO2,CAMK2D,CDC42,CDC42EP2,CDK19,CRK,CTSB,CXCR4,CYLD,DAB2IP,DCN,DNAJC3,EIF2AK3,ERCC6,EXOC1,FAP,FCER1G,GBP2,GRAMD4,GRN,GSK3B,HDAC5,HERC6,HK1,HRG,HYAL3,IFI35,IFIT3,IGHV3-74,IL17RA,IRF9,JAK1,LGALS3,LITAF,LRSAM1,LY96,LYST,MAPK1,MAPKAPK2,MICA,MST1R,MYO1C,NCF2,NLRP10,NOS3,NOTCH2,OPTN,OTUD5,PJA2,RAB43,RFTN1,RHOA,RTN4,SERINC3,SERINC5,SHFL,SIRPA,SIRPB1,SIRT2,SKP1,SLAMF6,SLC17A5,SLC26A6,SPON2,STAT2,STAT5B,STING1,STOX2,STX8,STXBP2,TANK,TBKBP1,TNFRSF14,TNFSF4,TOLLIP,TRAF6,TRIM21,TRIM35,VIM,VNN1,WASL,WDFY1 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 587 | 49 | APOC1,CD109,CDA,CHP1,CTDSP2,CYLD,DAB2IP,DACT1,DMTN,DNAJC3,DUSP3,EFNA1,GMFG,GNAI2,GSK3B,HGF,HIPK3,HMGCR,IGBP1,ILK,INPP5K,IQGAP1,LATS2,LGALS3,LRRK1,MICAL1,MYADM,PIK3IP1,PINK1,PKIG,PPEF2,PRKN,PRR5L,PSEN1,PTPRR,RAPGEF1,RHOA,RUBCN,SH3BP5,SIRPA,SIRT2,SMAD7,SMPD1,SNX6,SWAP70,TAOK3,TSC2,UBE2B,ZFYVE1 |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 526 | 46 | AACS,ACAT1,ACSL1,AKR1C3,AMBRA1,ASS1,BAIAP2,BCAS3,CASTOR2,CASTOR3,EEF2,EIF2AK3,FNIP1,FOXO4,GABARAP,GABARAPL2,GLUL,GNAI2,HMGCR,HMGCS1,HMOX1,LAMP2,MAP1B,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MAPK1,MEAK7,MTMR3,NCOA1,NQO1,P2RX6,PCSK9,RRAGC,SH3GLB1,SIRT2,SLC22A3,SLC38A2,TRPM4,TRPV4,UCN2,ULK1,WDR45,WDR59,WIPI1,ZFYVE1 |
| GO_CYTOSOLIC_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 159 | 25 | CLTCL1,DAB2,DENND10,EPS15,ERC1,HEATR5B,MAP2,MAP2K2,MAPK1,MON2,MSN,PRKN,RAB7A,RAB9A,RGP1,RILP,SNX6,SNX8,SPAG9,STX8,TBC1D17,TBC1D23,VPS11,WASHC2C,WIPI1 |
| GO_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1229 | 831 | 60 | ACO1,ANXA6,APP,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BTBD9,CALB1,CAMK2D,CEMIP,CHP1,CLCN3,CLIC4,CLN3,CP,CXCR4,CYBRD1,DCN,FTH1,FTL,GALR1,GNAI2,GRIN2D,GRINA,GRN,HMOX1,ITGAV,ITPR2,LRP1,MAPK1,MCOLN1,MCOLN3,MICU1,NCOA4,NDFIP1,PRKN,PSEN1,RAB7A,RCN3,ROGDI,SKP1,SLC12A4,SLC12A6,SLC26A4,SLC26A6,SLC31A2,SLC39A13,SLC4A3,SMAD7,SWAP70,TLCD2,TMEM165,TMEM38A,TRPM4,TRPM7,TRPV4 |
| GO_PROTEIN_TARGETING | 0.0e+00 | 0.0e+00 | 1229 | 428 | 41 | ACOT8,ACOX1,ATG13,CEMIP,CHM,CHP1,DMTN,EHHADH,EXOC4,GABARAP,GDI1,IDH1,INPP5K,KCNE1,LAMP2,LEPROT,MIEF2,MYO1C,NCOA4,NPEPPS,NUCB1,OS9,PAOX,PEX6,PHYH,PINK1,PMM1,PRKN,RAB7A,RAB8B,SCARB2,SDCBP,SH3GLB1,SRP14,TRAPPC8,VPS11,YWHAZ,ZDHHC1,ZDHHC2,ZDHHC7,ZFYVE16 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1117 | 72 | ACAN,ACAT1,ACOT8,ACSL1,ACSS2,ADCY2,AKR1C3,APP,ARNT,B3GNT2,B3GNT9,CDA,CEMIP,CHP1,CHPF,CSPG4,CST3,CTBS,CTNNB1,CTSA,DCN,ELOVL1,ESYT1,ESYT2,FN3K,FOXL1,GALNS,GALNT3,GK,GNS,GOLGA2,HGF,HK1,HMGCR,HMGCS1,HYAL3,INSR,MAN1A2,MAN2A1,MAN2A2,MANBA,MPC2,MT-ATP6,MT-ATP8,NAGK,NEU1,NT5C2,OS9,PGLS,PGM1,PGM2L1,PIGG,PINK1,PMM1,PRXL2C,PSAP,PSEN1,RAB23,RBKS,RHOA,RHOQ,RNF103,SCD,SDC2,SLC2A6,SMPD1,SOAT1,SULT1C2,TMEM165,TMEM59,UPB1,UST |
| GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1229 | 548 | 47 | AKAP13,APP,ATP6AP1,CAVIN3,CD81,CDC42,CHI3L1,CRK,CSPG4,CTNNB1,CXCR4,DAB2IP,DSTYK,EFNA1,ERCC6,ERP29,FZD8,GNAI2,GPNMB,HGF,HMGCR,ILK,INSR,IQGAP1,ITGA1,LAMTOR3,LRP1,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NOTCH2,PJA2,PRXL2C,PSAP,PSEN1,RAPGEF1,SDCBP,SPAG9,TAOK3,TGFBR1,TIMP2,TRAF6,TRPV4 |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 655 | 52 | ABI1,ACSL1,ADAM17,ADCY2,AKAP13,AMBRA1,ATG13,ATP2B4,CACUL1,CCNYL2,CD81,CDC42,CEMIP,CHI3L1,CRK,CSPG4,CTNNB1,CXCR4,DAB2IP,DSTYK,EFNA1,ERCC6,ERP29,FGF13,FZD8,GOLGA2,HGF,ILK,INSR,IQGAP1,ITGA1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NEDD9,PINK1,PSEN1,RAPGEF1,RHOA,SERINC1,SERINC2,SERINC5,SNX9,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 592 | 49 | ABI1,APP,AUTS2,B3GNT2,BAIAP2,CDC42,CUL7,CUX1,CXCR4,CYFIP1,DBN1,DOK4,EFNA1,EFNB3,FGF13,GDI1,GSK3B,ILK,ITGB1,LRP1,LZTS3,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,NRCAM,NUMB,OPHN1,PALLD,PDLIM7,PLXNA3,PSEN1,PTPRD,RHOA,RHOG,RTN4,SDC2,SEMA4B,SEMA6C,SKIL,SPTBN1,TOP2B,ULK1,UST,WASL,WDPCP,ZSWIM4,ZSWIM8 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 252 | 31 | ATP13A2,CAMLG,CD81,CSNK1D,DAB2,DAB2IP,DACT1,DNAJB2,EFNA1,FURIN,GABARAPL2,GSK3B,LRP1,MSN,MTM1,OPHN1,OS9,PCSK9,PINK1,PRKN,PSEN1,PTTG1IP,RGP1,RHBDF1,RNF14,SDCBP,SIRT2,SMAD7,UBXN1,VPS11,ZER1 |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 1000 | 67 | AAMDC,ACVR1,ARNT,ATP6AP1,AVIL,BAIAP2,CDC42,CREBL2,CRK,CSNK1D,CTNNA1,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,CYLD,DAB2,DAB2IP,DBN1,DMTN,GDI1,GNAS,GRN,HGF,ILK,IQGAP1,LRP1,LTBP3,MACF1,MAN2A1,MAP1B,MAP2K2,MDK,MYADM,MYLK3,NCOA1,NEDD9,NOTCH2,NRCAM,NUMB,PAX8,PDLIM7,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,SAV1,SCARB2,SDCBP,SIRT2,SKIL,SPAG9,STAT5B,TGFBR1,TIMP2,TNFSF4,TRAF6,TRPM4,VNN1,WNT5B,ZMIZ1 |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 1175 | 74 | ACAN,ACVR1,AKAP13,APOD,BCAS3,CALCRL,CDC42,CERT1,CHI3L1,CLIC4,CRELD1,CSPG4,CTDP1,CTNNB1,CUL7,CXCR4,DAB2IP,DCN,DSP,DYSF,EFNA1,EIF2AK3,ESM1,FAP,FOXL1,FOXO4,FZD8,GAA,GLUL,GPNMB,GRN,HDAC5,HECTD1,HGF,HIF3A,HMOX1,HRG,HTATIP2,ILK,INSR,ITGAV,ITGB1,JAK1,KLF2,LRP1,MAP2K2,MAPK1,MDK,MFGE8,MYLK3,NOS3,NOTCH2,NR4A1,NRCAM,NSDHL,PAX8,PDLIM7,PRCP,PSEN1,RAPGEF1,RHOA,RRAS,RTN4,SAV1,SCX,SGCB,SGPL1,SLC12A6,SMAD7,TGFBR1,TSC2,UBE4B,WDPCP,ZMIZ1 |
| GO_PROTEIN_POLYMERIZATION | 0.0e+00 | 0.0e+00 | 1229 | 273 | 32 | AKAP9,ARPC3,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42EP2,CHMP2A,CORO1B,CSNK1D,CYFIP1,DBN1,DMTN,FGF13,GMFG,GOLGA2,KANK1,MAP1B,MAP2,MAP7D3,MYADM,MYO1C,PINK1,PRKN,RHOA,SNX9,SPTBN1,TRPV4,WASHC2C,WASHC3,WASL |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 518 | 45 | ACSL1,ADAM17,AKAP13,ATP2B4,CCNG1,CCNI,CCNYL2,CD81,CEMIP,CRK,CSPG4,CXCR4,DAB2IP,DUSP3,ERCC6,ERP29,FZD8,HGF,HIPK3,HMGCR,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,LATS2,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1,MST1R,PKIG,PPEF2,PSEN1,RAPGEF1,RHOA,SMPD1,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 326 | 35 | AVIL,CALCOCO2,CAPG,CAPZB,CHMP1B,CHMP2A,CLN3,CTNNB1,DMTN,DSTN,FGF13,FRAT1,GABARAP,GABARAPL2,GSK3B,INSR,LAMP2,MAP1B,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MCOLN1,MICAL1,NCKAP5L,NSF,RUBCN,SHFL,SNX14,SPEF1,SPTBN1,SWAP70,TRIM54,TRPV4,TTBK2,WASHC2C |
| GO_CELL_MATRIX_ADHESION | 0.0e+00 | 0.0e+00 | 1229 | 226 | 29 | APOD,BCAS3,CD63,COL13A1,CORO2B,CTNNB1,DMTN,DUSP3,FBLN5,GSK3B,HRG,ILK,IQGAP1,ITGA1,ITGA7,ITGAV,ITGB1,LIMCH1,LRP1,MACF1,MADCAM1,NID1,PEAK1,RHOA,SGCE,SORBS1,THBS3,TRPM7,WDPCP |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 1229 | 1114 | 71 | ABRAXAS1,ARNT,CAMLG,CDC42,CHP1,CTNNB1,CUL7,CYLD,DCAF6,DNAJB2,DYSF,FBXL12,FBXL2,FBXO25,FBXO32,FOXO4,GOLGA2,HECTD1,HECTD4,HERC6,HIF3A,KCTD10,KCTD21,KLHL24,LRRC29,LRSAM1,MIB2,MINDY2,NDFIP1,NPEPPS,OS9,OTUD5,PINK1,PJA2,PRKN,PSEN1,PTTG1IP,RHOA,RHOT1,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SHARPIN,SKP1,SMAD7,SPSB3,SQSTM1,TANK,TBC1D7,TGFBR1,TOLLIP,TRAF6,TRIM21,TRPC4AP,TRPM4,UBA1,UBE2B,UBE2H,UBE2R2,UBE4B,UBR2,UBXN1,USP11,USP6,USP9Y,WDSUB1,WDTC1,ZMIZ1 |
| GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 227 | 29 | APOD,ATG13,ATP13A2,BCAS3,CD81,CDC42,CEMIP,CHP1,DMTN,GDI1,GSK3B,INPP5K,INSIG1,KCNE1,LEPROT,MAPK1,MIEF2,MYO1C,NPEPPS,NUCB1,OS9,PINK1,PKIG,PRKN,PRR5L,PSEN1,RAB23,SH3GLB1,VPS11 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1229 | 973 | 65 | AACS,ABHD2,ACAT1,ACSL1,ADCY2,AKAP13,AKAP9,AKR1C3,APP,AQP9,ARNT2,ASS1,ATP2B4,CALCOCO1,CREBRF,CTNNA1,CTNNB1,CXCR4,DAB2,DMTN,EEF2,FBXO32,FIBIN,GNAS,GRAMD1A,GSK3B,HCN3,HDAC5,HMGCS1,IDH1,INPP5K,INSIG1,ITPR2,KCNE1,KLF2,LBH,MAP1B,MAP1LC3A,MAPK1,MDK,MSN,MT-ND6,NCOA1,NCOA4,NCOR2,NQO1,NR4A1,NRIP1,P2RX6,PLPP1,PRKN,RAPGEF1,RFTN1,RHOA,RNF14,SIRT2,SLC26A6,SMPD1,STAT5B,STING1,TGFBR1,TMEM38A,TRIP4,TRPM4,WBP2 |
| GO_STEROID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 331 | 35 | ACAT1,ACAT2,ACOT8,AKR1C3,APOBR,APOC1,APP,CLN8,CYB5R3,CYP51A1,CYP8B1,DHCR24,EBP,ERG28,FDFT1,FDPS,HMGCR,HMGCS1,HSD17B11,HSD17B2,IDI1,INSIG1,LSS,MSMO1,NSDHL,OSBPL1A,OSBPL2,PCSK9,SC5D,SCD,SGPL1,SMPD1,SOAT1,STARD4,STAT5B |
| GO_CELLULAR_RESPONSE_TO_PEPTIDE | 0.0e+00 | 0.0e+00 | 1229 | 388 | 38 | ADCY2,APP,ASS1,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CRK,CYFIP1,FOXO4,GNAI2,GSK3B,HDAC5,INPP5K,INSR,KANK1,KLF11,KLF2,LEPROT,LPIN1,LPIN2,LRP1,MAP1B,MYO1C,NR4A1,PCSK9,PSEN1,RAB31,RAB8B,RHOQ,SNX6,SORBS1,STAT5B,TSC2,VIM,WDTC1 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1670 | 92 | ABI1,ABR,ACTG1,ADAM17,AGO4,APLF,APOD,APP,ARNT,ARPC3,ATP6AP1,BAIAP2,C1S,CD276,CD81,CDC42,CRK,CTNNB1,CTSB,CYFIP1,CYLD,DAB2IP,DNASE1,DNASE2,DUSP3,DYSF,EFNB3,ERCC6,FCER1G,FCGRT,FNIP1,GNAS,GPNMB,GRAMD4,GRN,HK1,HMOX1,HRG,IGHV3-74,ITGB1,JAK1,KLF13,KMT2C,LGALS3,LY96,MADCAM1,MAP3K8,MAPK1,MAPKAPK2,MDK,MICA,MOSPD2,MSN,MST1,MTUS1,MYO1C,NDFIP1,NLRP10,NOTCH2,PJA2,PROS1,PSEN1,RAPGEF1,RFTN1,RHOA,RHOG,RTN4,SIRPA,SIRPB1,SKP1,SLAMF6,SMAD7,SPON2,STAT5B,STING1,STX7,STXBP2,SWAP70,TANK,TAPBPL,TCTA,TMEM102,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4,TWSG1,VNN1,WASL,WDFY1,ZMIZ1 |
| GO_REGULATION_OF_CELL_SHAPE | 0.0e+00 | 0.0e+00 | 1229 | 156 | 24 | ARAP1,BAIAP2,C15orf62,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,CFAP410,CRK,CYFIP1,DMTN,ERMN,FBLIM1,ITGA7,MSN,MYL12B,PLEKHO1,PLXNA3,RHOA,RHOC,RHOG,RHOQ,S100A13,WDPCP |
| GO_LYSOSOMAL_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 104 | 20 | DENND3,GRN,IGF2R,LAMP2,LRP1,LYST,MTM1,NCOA4,PCSK9,PINK1,PRKN,PSAP,RAB7A,RILP,SCARB2,STX8,UBXN6,VIPAS39,VPS11,ZFYVE16 |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 0.0e+00 | 1229 | 1210 | 74 | ACSL1,ACTG1,ADAM17,APP,ARID5B,ASS1,B3GNT2,CALCOCO2,CAMK2D,CDC42,CDC42EP2,CHI3L1,CREBRF,CRK,CSF2RA,CXCR4,CYLD,DAB2IP,FCER1G,GBP2,GSK3B,HGF,HMOX1,HYAL3,IFI35,IFIT3,IGBP1,IL17RA,ILK,INPP5K,IRF9,ITGB1,JAK1,KDM5B,KLF2,MADD,MAP3K8,MAPK1,MAPKAPK2,MSN,MST1R,MYLK3,MYO1C,NFAT5,OSMR,PMM1,PRKN,RAB43,RAPGEF1,RHOA,SHARPIN,SHFL,SIRPA,SKIL,SKP1,SLC26A6,SMAD7,SQSTM1,STAT2,STAT5B,STING1,STX3,STX8,STXBP2,TANK,TIMP2,TMEM102,TNFRSF14,TNFSF4,TOLLIP,TRAF6,TRIM21,VIM,YWHAZ |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 1229 | 1061 | 68 | AACS,ABHD2,ACSL1,ADAM17,ADCY2,APOD,ASS1,ATP2B4,BAIAP2,CASTOR2,CASTOR3,CHRNB1,CLN8,CRK,CTNNA1,CTNNB1,CXCR4,CYP2W1,EEF2,FBXO32,FIBIN,GALR1,GNAI2,GNAS,GSK3B,HADHA,HCN3,HDAC5,HGF,HMGCR,HMGCS1,HMOX1,ITPR2,KLF2,LMBRD1,MAP1B,MAP1LC3A,MAPK1,MDK,MT-ND5,MT-ND6,NCOA1,NQO1,NUCB1,OSER1,P2RX6,PINK1,PRKN,PSAP,PSEN1,RHOA,SIRPA,SLC13A1,SLC15A4,SLC22A3,SLC26A6,SLC38A7,SMPD1,SRP14,SYT15,TIMP2,TMEM38A,TP53INP1,TRPM4,UBE2B,VIM,WBP2,ZNF277 |
| GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 577 | 47 | ABI1,ACSL1,ADAM17,ADCY2,AKAP13,AMBRA1,ATG13,ATP2B4,CACUL1,CCNYL2,CD81,CDC42,CEMIP,CHI3L1,CRK,CSPG4,CXCR4,DAB2IP,DSTYK,EFNA1,ERCC6,ERP29,FGF13,FZD8,HGF,ILK,INSR,IQGAP1,ITGA1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,NEDD9,PINK1,PSEN1,RAPGEF1,RHOA,SNX9,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1229 | 188 | 26 | CD81,CEMIP,CHP1,DAB2,DMTN,GDI1,INPP5K,ITGB1,KCNE1,LGALS3,LRP1,MIEF2,MYO1C,NUMB,PRKN,RHOG,RHOQ,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,TMBIM1,TMEM59,YWHAZ |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 1229 | 944 | 63 | ACOT8,ACOX1,APOD,ATG13,ATP13A2,ATP6V1D,CD81,CHP1,CSNK1D,DCTN2,EHHADH,EIF2AK3,EPS15,GBP2,GLIS2,GLUL,GOLGB1,GSK3B,HK1,IDH1,INSIG1,LAMP2,LEPROT,LRSAM1,MAPK1,MARK4,MEAK7,MOAP1,MSN,NCOA4,NPEPPS,NUMB,OPHN1,OPTN,OS9,PAOX,PEX6,PHYH,PINK1,PKIG,PMM1,PRKN,PSEN1,PTTG1IP,RAB23,RAB7A,RAB8B,RTN4,SCARB2,SH3GLB1,SKP1,SRP14,TAPT1,TINF2,TOLLIP,TRAPPC8,TSC2,TTBK2,VPS11,WASHC2C,WDR19,YWHAZ,ZFYVE16 |
| GO_LIPID_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 417 | 39 | ABCA9,ACSL1,ALKBH7,APOBR,APOC1,APOD,AQP9,ATP10D,ATP11A,ATP9A,CERT1,CLN8,DYSF,ESYT1,ESYT2,GALR1,GRAMD1A,ITGAV,KDM5B,LRP1,LRP10,NCOA1,NRIP1,OSBPL1A,OSBPL2,PCSK9,PITPNM1,PLA2R1,PNPLA2,PRKN,PSAP,SCARB2,SLC10A6,SOAT1,SPNS1,STARD4,STAT5B,XKR8,XKR9 |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 1177 | 72 | ABI1,ACTG1,ACVR1,ADAM17,AKAP13,APOD,BCAS3,CALB1,CALCRL,CD109,CD81,CDC42,CHI3L1,CLIC4,COL6A1,CSPG4,CTNNB1,CXCR4,DAB2IP,DCN,DYSF,EFNA1,EIF2AK3,ESM1,EXOC4,FAP,FER1L5,FOXO4,FZD8,GLUL,GPNMB,GRN,HDAC5,HGF,HIF3A,HMOX1,HRG,HTATIP2,ILK,ITGA7,ITGAV,ITGB1,JAK1,KLF2,MAP2K2,MAPK1,MDK,MFGE8,MYLK3,NOS3,NOTCH2,NR4A1,NRCAM,OPHN1,PAX8,PLEKHO1,PMP22,PRCP,PSEN1,RHOA,RRAS,RTN4,SCX,SKIL,SLC12A6,TCTA,TGFBR1,THBS3,TRAF6,TSC2,TWSG1,TXNRD1 |
| GO_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 259 | 30 | ARAP1,ARPC3,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42,CDC42EP2,CORO1B,CORO2B,CYFIP1,DBN1,DMTN,DSTN,GMFG,INPP5K,KANK1,LIMCH1,MYADM,MYO1C,PRKN,RHOA,RHOC,SNX9,SPTBN1,SWAP70,TGFBR1,WASHC2C,WASL |
| GO_REGULATION_OF_CELL_SIZE | 0.0e+00 | 0.0e+00 | 1229 | 179 | 25 | CLCN3,CLCN6,CLN8,CYFIP1,DBN1,FGF13,GDI1,GSK3B,ILK,LRP1,LRRC8A,MACF1,MAP1B,MAP2,MSN,NRCAM,PLXNA3,RHOA,RTN4,SEMA4B,SEMA6C,SLC12A4,SLC12A6,TRPV4,WDTC1 |
| GO_AUTOPHAGY_OF_MITOCHONDRION | 0.0e+00 | 0.0e+00 | 1229 | 75 | 17 | AMBRA1,ATG13,ATG2B,ATP13A2,FUNDC2,GABARAP,GABARAPL2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,OPTN,PINK1,PRKN,SQSTM1,TSC2,WDR45,WIPI1 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1229 | 469 | 41 | CD109,CHP1,CTDSP2,CYLD,DAB2IP,DACT1,DMTN,DNAJC3,DUSP3,EFNA1,GMFG,HGF,HIPK3,HMGCR,IGBP1,ILK,INPP5K,LATS2,LRRK1,MICAL1,MYADM,PIK3IP1,PINK1,PKIG,PPEF2,PRKN,PRR5L,PSEN1,PTPRR,RAPGEF1,RHOA,RUBCN,SH3BP5,SIRPA,SIRT2,SMAD7,SMPD1,SNX6,TAOK3,TSC2,UBE2B |
| GO_ORGANELLE_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 100 | 19 | AMBRA1,ATG13,ATG2B,ATP13A2,FUNDC2,GABARAP,GABARAPL2,GOLGA2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,OPTN,PINK1,PRKN,SQSTM1,STING1,TSC2,WDR45,WIPI1 |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 0.0e+00 | 1229 | 687 | 51 | ABHD2,ACTG1,ADAM17,ANXA6,APOD,CAPZB,CD109,CD151,CD81,CDC42,CORO1B,CPQ,CRK,CTNNA1,CXCR4,DCN,DGKD,DMTN,DSP,DST,DYSF,FAP,FCER1G,GNAS,GRN,HMGCR,HMOX1,HRG,ILK,ITPR2,KANK1,LRP1,MACF1,MAFK,MAP1B,MAP2K2,MAPK1,MDK,MICAL1,MYL12A,NOS3,NOTCH2,P2RX6,PHF21A,PRCP,PROS1,RHOA,RHOC,TGFBR1,WNT5B,YWHAZ |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 432 | 39 | AKAP9,ARPC3,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42,CDC42EP2,CORO1B,CYFIP1,DAB2IP,DACT1,DBN1,DMTN,FBLIM1,FNIP1,GMFG,GSK3B,HRG,KANK1,MAP1B,MAP2,MIEF2,MSN,MYADM,MYO1C,PINK1,PPP2R5B,RHOA,RHOC,SH3GLB1,SIRT2,SNX9,SPTBN1,ULK1,VPS11,WASHC2C,WASL |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 113 | 20 | APOD,CHP1,DAB2,DMTN,GDI1,GSK3B,INPP5K,INSIG1,KCNE1,LEPROT,NUMB,OS9,PKIG,RAB23,RHOQ,SNX33,TMBIM1,TMEM59,TP53INP2,TTBK2 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 337 | 34 | ACSL1,ADAM17,AKAP13,ATP2B4,CCNYL2,CD81,CEMIP,CRK,CSPG4,CXCR4,DAB2IP,ERCC6,ERP29,FZD8,HGF,ILK,INSR,IQGAP1,ITGA1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,PSEN1,RAPGEF1,RHOA,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 414 | 38 | ACOX1,ACSL1,AKR1C3,AMBRA1,APOC1,APOD,CD81,CDC42,CHD9,CREBL2,CYP51A1,DAB2IP,FDFT1,FDPS,HMGCR,HMGCS1,IDH1,IDI1,INSIG1,LACTB,LSS,MTMR3,NCOA1,NCOR2,PIK3IP1,PLPP1,PNPLA2,PSAP,RUBCN,SAMD8,SC5D,SCD,SORBS1,STARD4,STAT5B,TIAM2,TXNRD1,WDTC1 |
| GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 338 | 34 | AKAP13,CD81,CRK,CSPG4,CXCR4,DAB2IP,DUSP3,ERCC6,ERP29,FZD8,HGF,HIPK3,HMGCR,ILK,INPP5K,INSR,IQGAP1,ITGA1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,PPEF2,PSEN1,RAPGEF1,SMPD1,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 562 | 45 | ATP6AP1,AVIL,BAIAP2,CDC42,CRK,CSNK1D,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,DMTN,GDI1,GRN,HGF,ILK,IQGAP1,LRP1,MACF1,MAN2A1,MAP1B,MAP2K2,MDK,MYADM,MYLK3,NCOA1,NEDD9,NRCAM,NUMB,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,SCARB2,SIRT2,SKIL,SPAG9,TIMP2 |
| GO_MUSCLE_STRUCTURE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 673 | 50 | ACTG1,ACVR1,AKAP13,ARID5B,ASS1,CD164,CD81,CDC42,CHD2,CHRNB1,CTDP1,CTNNA1,CTNNB1,DCN,DSP,DYSF,EEF2,EVC,FER1L5,FOXO4,GPCPD1,HDAC5,HMGCR,ILK,ITGA7,ITGB1,MAPK1,MTM1,MYL6,MYL6B,MYLK3,PDLIM7,PLEKHM3,PLEKHO1,RHOA,SAV1,SCX,SGCB,SGCE,SIRT2,SMAD7,SPAG9,SRPK3,SVIL,TAGLN,TGFBR1,TRIP4,UBE4B,UNC45A,ZFHX3 |
| GO_AXON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 523 | 43 | APOD,APP,AUTS2,B3GNT2,BAIAP2,CTNNA1,CXCR4,CYFIP1,DBN1,DOK4,EFNA1,EFNB3,FGF13,GDI1,GRN,GSK3B,ILK,ITGB1,LRP1,MACF1,MAP1B,MAP2,MAP2K2,MAPK1,NRCAM,NUMB,OPHN1,PALLD,PDLIM7,PLXNA3,PSEN1,RHOA,RHOG,RTN4,SEMA4B,SEMA6C,SKIL,SPTBN1,TOP2B,ULK1,UST,ZSWIM4,ZSWIM8 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 0.0e+00 | 1229 | 912 | 60 | ARNT,CAMLG,CDC42,CHP1,CTNNB1,CUL7,DCAF6,DNAJB2,DYSF,FBXL12,FBXL2,FBXO25,FBXO32,GOLGA2,HECTD1,HECTD4,HERC6,HIF3A,KCTD10,KCTD21,KLHL24,LRRC29,LRSAM1,MIB2,NDFIP1,NPEPPS,OS9,PINK1,PJA2,PRKN,PSEN1,PTTG1IP,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SHARPIN,SKP1,SMAD7,SPSB3,SQSTM1,TBC1D7,TGFBR1,TOLLIP,TRAF6,TRIM21,TRPC4AP,TRPM4,UBA1,UBE2B,UBE2H,UBE2R2,UBE4B,UBR2,UBXN1,WDSUB1,WDTC1,ZMIZ1 |
| GO_RESPONSE_TO_PEPTIDE | 0.0e+00 | 0.0e+00 | 1229 | 525 | 43 | ADCY2,APP,ASS1,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CRK,CYFIP1,FOXO4,GNAI2,GSK3B,HADHA,HDAC5,INPP5K,INSR,IQGAP1,KANK1,KLF11,KLF2,LEPROT,LPIN1,LPIN2,LRP1,MAP1B,MEAK7,MYO1C,NR4A1,PCSK9,PSEN1,RAB31,RAB8B,RHOQ,SNX6,SORBS1,STAT2,STAT5B,TRPV4,TSC2,VIM,WDTC1 |
| GO_RESPONSE_TO_STARVATION | 0.0e+00 | 0.0e+00 | 1229 | 189 | 25 | AACS,ACAT1,AKR1C3,AMBRA1,BCAS3,EIF2AK3,FNIP1,GABARAP,GABARAPL2,GLUL,LAMP2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MAPK1,MTMR3,PCSK9,RRAGC,SH3GLB1,SLC38A2,ULK1,WDR45,WDR59,WIPI1,ZFYVE1 |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 547 | 44 | ACAT2,ACOT8,ACSS2,ADH5,AKR1C3,APOBR,APOC1,APP,BTBD9,CLN8,CPQ,CTNS,CYB5R3,CYP51A1,CYP8B1,DHCR24,DYSF,EBP,ERG28,FDFT1,FDPS,GK,HMGCR,HMGCS1,IDH1,IDI1,INPP5K,INSIG1,IP6K1,LSS,MSMO1,NSDHL,OSBPL1A,OSBPL2,PAX8,PCSK9,PRKN,RETSAT,SC5D,SCD,SMPD1,SOAT1,SPTLC1,STARD4 |
| GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | 0.0e+00 | 0.0e+00 | 1229 | 205 | 26 | ABI1,ARPC3,AVIL,BAIAP2,C15orf62,CAP1,CAPG,CAPZB,CDC42EP2,CORO1B,CYFIP1,DBN1,DMTN,DSTN,GMFG,KANK1,MICAL1,MYADM,MYO1C,RHOA,SNX9,SPTBN1,SWAP70,WASHC2C,WASHC3,WASL |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1229 | 614 | 47 | AACS,ABHD2,ADCY2,AKAP13,AKAP9,AKR1C3,APP,AQP9,ASS1,ATP2B4,CALCOCO1,CREBRF,CTNNA1,CTNNB1,DAB2,DMTN,FBXO32,GNAS,GRAMD1A,GSK3B,HCN3,HMGCS1,INPP5K,INSIG1,ITPR2,KCNE1,KLF2,LBH,MAPK1,MSN,NCOA1,NCOA4,NCOR2,NR4A1,NRIP1,PLPP1,PRKN,RAPGEF1,RHOA,RNF14,SIRT2,SLC26A6,STING1,TMEM38A,TRIP4,TRPM4,WBP2 |
| GO_CELLULAR_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1229 | 683 | 50 | ACO1,ANXA6,APP,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CALB1,CAMK2D,CEMIP,CHP1,CLCN3,CLIC4,CLN3,CP,CXCR4,CYBRD1,FTH1,FTL,GALR1,GRIN2D,GRINA,GRN,HMOX1,ITGAV,ITPR2,LRP1,MAPK1,MCOLN1,MCOLN3,MICU1,NCOA4,NDFIP1,PSEN1,RAB7A,ROGDI,SKP1,SLC26A6,SLC31A2,SLC39A13,SLC4A3,SWAP70,TMEM165,TMEM38A,TRPM4,TRPM7,TRPV4 |
| GO_GOLGI_VESICLE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 367 | 35 | ATP9A,CAPZB,COPG1,CSNK1D,CUX1,DCTN2,DYNC1H1,EPS15,EXOC1,EXOC4,EXOC6B,GABARAPL2,GOLGA2,GOLGB1,INSIG1,KIF3C,KIFAP3,MACF1,MON2,NRBP1,NSF,OPTN,PROS1,RAB31,RAB8B,RP2,SCAMP2,SNAP23,SNX8,SPTBN1,TMED4,TRAPPC6A,TRAPPC8,WIPI1,YIPF5 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1229 | 751 | 53 | ABRAXAS1,APP,CAMK2D,CDC42,CORO2B,CTNNB1,CYLD,DAB2IP,DACT1,DNAJC3,DUSP3,EIF2AK3,ERCC6,ERP29,FBLN5,FZD8,GRINA,GRN,GSK3B,HGF,HIPK3,HMGCR,IGBP1,INSIG1,LRP1,MAP2K2,MAP3K10,MAPK1,MAPKAPK2,MEAK7,MICU1,NUAK1,OS9,PINK1,PJA2,PLA2R1,PPEF2,PRKN,PSAP,PTTG1IP,RAPGEF1,SDCBP,SERINC3,SIRPA,SKIL,SPAG9,TAOK3,TRAF6,TRPV4,UBXN1,VNN1,YPEL3,ZNF277 |
| GO_WOUND_HEALING | 0.0e+00 | 0.0e+00 | 1229 | 572 | 45 | ACTG1,ADAM17,ANXA6,APOD,CAPZB,CD109,CD151,CD81,CDC42,CORO1B,CPQ,CRK,CXCR4,DCN,DGKD,DMTN,DSP,DST,DYSF,FAP,FCER1G,GNAS,HMGCR,HMOX1,HRG,ILK,ITPR2,KANK1,MACF1,MAFK,MAPK1,MDK,MICAL1,MYL12A,NOS3,NOTCH2,P2RX6,PHF21A,PRCP,PROS1,RHOA,RHOC,TGFBR1,WNT5B,YWHAZ |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1870 | 96 | ABRAXAS1,ACVR1,APLF,APP,ARID5B,ARMCX3,ARNT,ARNT2,ATP1B4,AUTS2,BCAS3,CALCOCO1,CAMTA2,CD81,CREBL2,CREBRF,CTCFL,CTNNB1,DAB2,DAB2IP,DCAF6,DCN,EAPP,EGR4,EIF2AK3,ERCC6,FANK1,FOSL2,FOXO4,GALR1,GLIS2,GLMP,HCFC2,HDAC5,HGF,HIF3A,HTATIP2,ILK,ING4,INPP5K,INSIG1,INSR,KDM5A,KLF12,KLF13,KLF2,KLF6,KMT2C,LBH,LITAF,LPIN1,LPIN2,MAP2K2,MAPK1,MDK,MOSPD1,NCOA1,NCOA4,NFAT5,NOS3,NR4A1,NRIP1,PAX8,PINK1,PPP2R5B,PRKN,PRR5L,PRXL2C,PSEN1,RHOG,RHOQ,RNF14,SCX,SERTAD3,SIRT2,SMAD7,SMAD9,SQSTM1,STAT2,STAT5B,STING1,TEAD1,TGFBR1,TNFSF4,TP53INP1,TP53INP2,TRAF6,TRIP4,UBE2B,WASL,WBP2,ZFHX2,ZFHX3,ZMIZ1,ZNF281,ZXDC |
| GO_MODIFICATION_DEPENDENT_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 642 | 48 | CACUL1,CAMLG,CSNK1D,CTNNB1,CUL7,CYLD,DAB2,DNAJB2,FBXL12,FBXL2,GSK3B,KCTD10,KCTD21,LRRC29,MTM1,MVB12B,NDFIP1,OS9,PINK1,PRKN,PSEN1,RNF103,RNF11,RNF130,RNF133,RNF14,RNF146,SDCBP,SHARPIN,SIRT2,SKP1,SMAD7,SPSB3,SQSTM1,TOLLIP,TP53INP2,TRPC4AP,TUT7,UBA1,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,USP11,USP6,USP9Y,ZER1 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 0.0e+00 | 0.0e+00 | 1229 | 351 | 34 | AKR1C3,ARNT,ATP13A2,CRK,CTNNB1,DYSF,EIF2AK3,FBLN5,HGF,HMOX1,KLF2,MAP1LC3A,MAPK1,MEAK7,MICU1,NCF2,NOS3,NQO1,OSER1,PINK1,PLA2R1,PRDX5,PRKN,PRR5L,PSAP,SERPINB6,SIRPA,SIRT2,SLC12A6,TP53INP1,TRPV4,TXNRD1,VNN1,ZNF277 |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 1124 | 68 | ABR,ADAM17,APOD,CALCRL,CD109,CD81,CDK19,CORO1B,CRK,CTSB,CXCR4,CYLD,DAB2IP,DMTN,DNASE1,DUSP3,DYSF,ERCC6,FAP,FCER1G,FNDC4,GRAMD4,GRN,HGF,HMGCR,HRG,IL17RA,JAK1,LRP1,LRSAM1,LY96,MAP2K2,MAPKAPK2,MDK,MICA,MOSPD2,MST1,MTUS1,NDFIP1,NLRP10,NOS3,OPTN,OSMR,PJA2,PLXNA3,PROS1,RFTN1,RTN4,SEMA4B,SEMA6C,SHARPIN,SIRPA,SIRT2,SKP1,SLAMF6,STAT5B,STING1,STX3,SWAP70,TANK,TBC1D23,TMEM102,TNFSF4,TRAF6,TRPV4,WDFY1,ZSWIM4,ZSWIM8 |
| GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 148 | 22 | ARAP1,AVIL,CAPG,CAPZB,CHMP2A,CORO1B,CORO2B,DMTN,FGF13,GMFG,INPP5K,KANK1,MAP1B,MAP2,MYADM,PRKN,SPEF1,SPTBN1,SWAP70,TRIM54,TTBK2,WASHC2C |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 134 | 21 | ATP13A2,CAMLG,CST3,CTSA,CYP51A1,DAB2IP,DYSF,EFNA1,FURIN,GABARAPL2,HMGCR,MTM1,OPHN1,OS9,PSEN1,RGP1,RILP,SDCBP,SIRT2,TIMP2,UBXN1 |
| GO_CYTOKINE_PRODUCTION | 0.0e+00 | 0.0e+00 | 1229 | 808 | 55 | ADAM17,ANXA4,APOD,APP,ARNT,ATP6AP2,CD276,CD81,CHI3L1,CTNNB1,CYLD,DYSF,EIF2AK3,FCER1G,FRMD8,FURIN,GPNMB,HGF,HK1,HMOX1,IL17RA,IQGAP1,ITGAV,KLF2,LITAF,LRP1,LTBP3,LY96,MAPKAPK2,MDK,NDFIP1,NFAT5,NLRP10,NOTCH2,OTUD5,PLA2R1,PSEN1,RFTN1,S100A13,SERPINB1,SIRPA,SLAMF6,SMAD7,SPON2,SPTBN1,STAT5B,STING1,TBC1D23,TNFRSF14,TNFSF4,TRAF6,TRIM21,TRPM4,TRPV4,TWSG1 |
| GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 0.0e+00 | 0.0e+00 | 1229 | 297 | 31 | APP,ARHGEF6,CDC42,CYLD,DAB2IP,DACT1,DUSP3,ERCC6,FZD8,HGF,HIPK3,HMGCR,IGBP1,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,PINK1,PJA2,PPEF2,PRKN,RAPGEF1,RHOA,SDCBP,SIRPA,SKP1,SPAG9,TAOK3,TRAF6,TRPV4 |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 810 | 55 | ACVR1,APOD,BCAS3,CALCRL,CDC42,CHI3L1,CLIC4,CSPG4,CTNNB1,CUL7,CXCR4,DAB2IP,DCN,DYSF,EFNA1,EIF2AK3,ESM1,FAP,FOXO4,FZD8,GLUL,GPNMB,GRN,HDAC5,HECTD1,HGF,HIF3A,HMOX1,HRG,HTATIP2,ITGAV,ITGB1,JAK1,KLF2,LRP1,MAPK1,MDK,MFGE8,NOS3,NOTCH2,NR4A1,NRCAM,NSDHL,PRCP,PSEN1,RAPGEF1,RHOA,RRAS,SGCB,SGPL1,SLC12A6,SMAD7,TGFBR1,WDPCP,ZMIZ1 |
| GO_STEROL_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 84 | 17 | ACAT2,CYB5R3,CYP51A1,DHCR24,EBP,ERG28,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,INSIG1,LSS,MSMO1,NSDHL,SC5D,SCD |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 860 | 57 | AHNAK,AKAP9,ANO10,ANXA6,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BEST1,CAMK2D,CD63,CEMIP,CHP1,CLCN3,CLCN6,CLCN7,CLIC4,COX6A1,COX6C,DYSF,GRIN2D,HCN3,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,MCOLN1,MCOLN3,MICU1,MT-ATP6,MT-ATP8,NIPA1,PCSK9,PSEN1,SESTD1,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC17A5,SLC26A11,SLC26A4,SLC26A6,SLC2A6,SLC31A2,SLC37A1,SLC39A13,TMCO3,TMEM38A,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 264 | 29 | AKR1C3,AMBRA1,BAIAP2,CASTOR2,CASTOR3,EIF2AK3,FNIP1,GABARAP,GABARAPL2,GLUL,HMOX1,LAMP2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MAPK1,MTMR3,NCOA1,PCSK9,RRAGC,SH3GLB1,SLC38A2,TRPM4,UCN2,ULK1,WDR45,WDR59,WIPI1,ZFYVE1 |
| GO_ALCOHOL_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 377 | 35 | ACAT2,ACSS2,ADH5,AKR1C3,APOBR,APOC1,APP,CLN8,CYB5R3,CYP51A1,DHCR24,DYSF,EBP,ERG28,FDFT1,FDPS,GK,HMGCR,HMGCS1,IDH1,IDI1,INPP5K,INSIG1,IP6K1,LSS,MSMO1,NSDHL,OSBPL1A,PCSK9,RETSAT,SC5D,SCD,SMPD1,SOAT1,SPTLC1 |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 0.0e+00 | 1229 | 940 | 60 | ABI1,ACOT8,ATF7,BRD2,CALCOCO2,CAMLG,CD81,CDC42,CHMP1B,CHMP2A,CTDP1,CTNNB1,CTSB,CUL7,CXCR4,EFNB3,EPS15,EXOC1,FBXL2,FDPS,FURIN,HCFC2,HRG,HTATIP2,HYAL3,IGF2R,INPP5K,INSR,IQGAP1,ITGAV,ITGB1,KDM4A,LMBRD1,LRSAM1,MAPK1,MICA,MSN,MVB12B,PC,PRKN,RAB43,RAB7A,RAB9A,RHOA,SCARB2,SERINC5,SHFL,SKP1,STAT2,STING1,TANK,TBKBP1,TNFRSF14,TOP2B,TRIM21,TRIM35,TSC2,UBXN1,ULK1,VIM |
| GO_REGULATION_OF_AXONOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 184 | 24 | CYFIP1,DBN1,EFNA1,EFNB3,FGF13,GDI1,GSK3B,ILK,LRP1,MACF1,MAP1B,MAP2,MAP2K2,NRCAM,PLXNA3,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,SKIL,UST,ZSWIM4,ZSWIM8 |
| GO_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 0.0e+00 | 0.0e+00 | 1229 | 268 | 29 | CD81,DAB2,FCER1G,FCHO2,FGF13,INPP5K,ITGB1,LGALS3,LRP1,MACF1,MYADM,NSF,NUMB,OPTN,RAB31,RAB8B,RHOG,RHOQ,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,TMBIM1,TMEM150A,TMEM59,TMEM88,TSPAN14 |
| GO_STEROID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 201 | 25 | ACAT2,ACOT8,AKR1C3,CYB5R3,CYP51A1,CYP8B1,DHCR24,EBP,ERG28,FDFT1,FDPS,HMGCR,HMGCS1,HSD17B11,HSD17B2,IDI1,INSIG1,LSS,MSMO1,NSDHL,OSBPL1A,OSBPL2,SC5D,SCD,STARD4 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1710 | 89 | ACVR1,APP,ARID5B,ARMCX3,ARNT,ARNT2,ATP1B4,AUTS2,BCAS3,CALCOCO1,CAMTA2,CD81,CREBL2,CREBRF,CTCFL,CTNNB1,DAB2,DAB2IP,DCAF6,DCN,EAPP,EGR4,EIF2AK3,ERCC6,FANK1,FOSL2,FOXO4,GALR1,GLIS2,GLMP,HCFC2,HDAC5,HGF,HIF3A,HTATIP2,ILK,ING4,INPP5K,INSIG1,INSR,KDM5A,KLF12,KLF13,KLF2,KLF6,KMT2C,LBH,LITAF,LPIN1,LPIN2,MAP2K2,MAPK1,MDK,MOSPD1,NCOA1,NCOA4,NFAT5,NR4A1,NRIP1,PAX8,PPP2R5B,PRKN,PRR5L,PSEN1,RHOG,RHOQ,RNF14,SCX,SERTAD3,SIRT2,SMAD7,SMAD9,SQSTM1,STAT2,STAT5B,STING1,TEAD1,TGFBR1,TP53INP1,TP53INP2,TRAF6,TRIP4,WASL,WBP2,ZFHX2,ZFHX3,ZMIZ1,ZNF281,ZXDC |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 0.0e+00 | 0.0e+00 | 1229 | 1200 | 70 | ACTG1,ADAM17,APP,ASS1,C1S,CALCOCO2,CAMK2D,CDC42,CDC42EP2,CRK,CTSB,CYLD,DAB2IP,DNAJC3,ERCC6,EXOC1,FCER1G,GBP2,GRAMD4,GRN,HK1,HRG,IFI35,IFIT3,IGHV3-74,IL17RA,IRF9,JAK1,LGALS3,LRSAM1,LY96,LYST,MAPKAPK2,MICA,MST1R,MYO1C,NCF2,NLRP10,NOTCH2,OPTN,PJA2,RAB43,RFTN1,RTN4,SERINC3,SERINC5,SHFL,SIRPA,SIRPB1,SIRT2,SKP1,SLAMF6,SLC26A6,SPON2,STAT2,STAT5B,STING1,STX8,STXBP2,TANK,TBKBP1,TNFRSF14,TNFSF4,TOLLIP,TRAF6,TRIM21,TRIM35,VIM,VNN1,WDFY1 |
| GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | 0.0e+00 | 0.0e+00 | 1229 | 219 | 26 | BCAS3,CAP1,CDC42,CLIC4,CRK,CTNNA1,CYTH1,DST,FAM89B,FGF13,FRMD4A,GSK3B,ILK,ITGB1,KANK1,MAP1B,MAP2,MSN,OPHN1,PARD3B,RHOA,RHOC,RHOG,RHOQ,UST,WDPCP |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 219 | 26 | CD81,CSNK1D,DAB2,DAB2IP,DACT1,DNAJB2,FURIN,GSK3B,LRP1,MSN,NDFIP1,NRDC,NSF,PCSK9,PRKN,PSEN1,PTTG1IP,RAB7A,RILP,RNF14,SIRT2,SMAD7,SNX33,SNX9,VPS11,ZER1 |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 406 | 36 | ARHGAP21,ATP6AP1,CDC42,CHMP1B,CHMP2A,CLN3,COPG1,CSNK1D,CTNNB1,DCTN2,DYNC1H1,EXOC4,FCER1G,GOLGA2,HMOX1,ITGB1,KIF3C,KIFAP3,MAP1B,MAP2,MYO1C,NSF,PARD3B,PINK1,PRKN,PSEN1,RHOT1,S100A13,SNAP23,STXBP2,TBC1D23,TRAPPC6A,UBE2B,WASL,WIPI1,YWHAZ |
| GO_NEGATIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 142 | 21 | ARAP1,AVIL,CAPG,CAPZB,CORO1B,CORO2B,DMTN,FGF13,GMFG,INPP5K,KANK1,MAP1B,MAP2,MYADM,PRKN,SPEF1,SPTBN1,SWAP70,TRIM54,TTBK2,WASHC2C |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 879 | 57 | AHNAK,AKAP9,ANO10,ANXA6,APP,ATP13A2,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CAMK2D,CAPN1,CD63,CEMIP,CHP1,CLCN3,COX6A1,COX6C,DYSF,GRIN2D,HCN3,ITGAV,ITPR2,KCNE1,KCNK6,KLHL24,MCOLN1,MCOLN3,MICU1,MT-ATP6,MT-ATP8,NIPA1,P2RX6,PCSK9,PINK1,PSEN1,SESTD1,SLC12A4,SLC12A6,SLC15A4,SLC17A5,SLC22A4,SLC2A6,SLC31A2,SLC38A7,SLC39A13,SLC41A2,TMCO3,TMEM38A,TMEM63B,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1229 | 1030 | 63 | ACVR1,AGO4,AMBRA1,ANXA4,ARHGAP10,ARNT2,ATP13A2,CHMP2A,CLN3,CLN8,CTNNA1,CTNNB1,DAB2,DHCR24,DNAJC3,DSTYK,EFNA1,ERC1,FANK1,FCER1G,FNIP1,GNAI2,GPNMB,GRINA,GRN,GSK3B,HGF,HIPK3,HMGCR,HMOX1,HTATIP2,IFIT3,IGBP1,ILK,ITGAV,ITGB1,KIFAP3,LGALS3,LRP1,MDK,MEAK7,MICAL1,NOS3,NOTCH2,NQO1,PAX8,PINK1,PRDX5,PRKN,PSAP,PSEN1,PTTG1IP,RHOA,SCX,SNX6,SQSTM1,STAT5B,TGFBR1,TMBIM1,TRAF6,UBE2B,VNN1,YWHAZ |
| GO_VESICLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 330 | 32 | ALS2CL,CHMP1B,CHMP2A,CLCN3,CSNK1D,DYSF,EPS15,GOLGA2,HPS1,INSIG1,LYST,NSF,PI4K2A,PRKN,RAB32,RAB5B,RAB7A,RAB8B,RILP,SCARB2,SDCBP,SNAP23,SNX33,SQSTM1,STX3,STX7,STX8,TMEM127,TRAPPC6A,VPS11,WASL,ZFYVE16 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1318 | 74 | ABR,ADAM17,ANXA4,APOC1,APOD,APP,ATP2B4,CALCRL,CST3,CTDP1,CTNNA1,CTNNB1,CYLD,CYP51A1,DAB2IP,DCN,EFNA1,EFNB3,EIF2AK3,FAP,FGF13,FOXO4,FURIN,GDI1,GNAI2,GPNMB,GPR161,GRN,GSK3B,HDAC5,HGF,HMGCR,HMOX1,HRG,HYAL3,IP6K1,KANK1,KLF13,KLF2,LRP1,LTBP3,MAP2,MDK,NDFIP1,NOS3,NRDC,OTUD5,PAX8,PCSK9,PLXNA3,PMP22,PROS1,PSEN1,PTPRR,RAB11FIP5,RHOA,RTN4,SAV1,SEMA4B,SEMA6C,SERPINB1,SIRPA,SIRT2,SMAD7,STAT5B,TCTA,TGFBR1,TNFSF4,TRPM4,TRPV4,TWSG1,VASN,VIM,ZHX2 |
| GO_RESPONSE_TO_OXIDATIVE_STRESS | 0.0e+00 | 0.0e+00 | 1229 | 453 | 38 | AKR1C3,APOD,APP,ARNT,ATP13A2,CLN8,CRK,CTNNB1,DHCR24,EEF2,ERCC6,FBLN5,HGF,HMOX1,IDH1,KLF2,MAP1LC3A,MAPK1,MEAK7,MT-ND5,MT-ND6,NCF2,NOS3,NQO1,OSER1,PINK1,PLA2R1,PRDX5,PRKN,PRR5L,PSAP,PSEN1,SIRPA,SIRT2,TP53INP1,TXNRD1,VNN1,ZNF277 |
| GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 314 | 31 | APOC1,ATP13A2,ATP2B4,CAMLG,CST3,CTSA,CYP51A1,DAB2IP,DYSF,EFNA1,FURIN,GABARAPL2,GOLGA2,HGF,HMGCR,HMOX1,KDM4A,MAPKAPK2,MTM1,OPHN1,OS9,PINK1,PSEN1,RGP1,RILP,RUBCN,SDCBP,SIRT2,TIMP2,TSC2,UBXN1 |
| GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1229 | 259 | 28 | AKAP13,CD81,CRK,CSPG4,CXCR4,DAB2IP,ERCC6,ERP29,FZD8,HGF,ILK,INSR,IQGAP1,ITGA1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,MST1R,PSEN1,RAPGEF1,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 0.0e+00 | 0.0e+00 | 1229 | 561 | 43 | ACO1,AKR1C3,ANXA11,APP,AQP9,ASS1,ATP13A2,ATP2B4,CAMK2D,CLIC4,CPNE3,CRK,CYBRD1,DMTN,EEF2,EIF2AK3,ERCC6,FBLN5,FIBIN,GDI1,HGF,HMGCS1,HMOX1,IQGAP1,KLF2,MAP1B,MAP1LC3A,MAPK1,MCOLN1,MT-ND5,MT-ND6,NOS3,NQO1,OSER1,PINK1,PRKN,PSAP,S100A13,SIRPA,SLC39A13,SYT15,TNFSF4,ZNF277 |
| GO_TAXIS | 0.0e+00 | 0.0e+00 | 1229 | 652 | 47 | ADAM17,APP,B3GNT2,CORO1B,CRK,CXCR4,CYFIP1,DOK4,DUSP3,DYSF,EFNA1,EFNB3,FCER1G,GPNMB,HGF,HRG,IL17RA,ITGA1,ITGAV,LGALS3,LRP1,LYST,MAPK1,MDK,MOSPD2,MST1,MTUS1,NR4A1,NRCAM,OPHN1,PALLD,PDLIM7,PIP5K1C,PLXNA3,RHOA,RHOG,SEMA4B,SEMA6C,SPTBN1,STX3,SWAP70,TMEM102,TRPM4,TRPV4,TSC2,ZSWIM4,ZSWIM8 |
| GO_CELLULAR_RESPONSE_TO_STARVATION | 0.0e+00 | 0.0e+00 | 1229 | 146 | 21 | AKR1C3,AMBRA1,EIF2AK3,FNIP1,GABARAP,GABARAPL2,GLUL,LAMP2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MAPK1,MTMR3,PCSK9,RRAGC,SH3GLB1,SLC38A2,WDR45,WDR59,WIPI1,ZFYVE1 |
| GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 394 | 35 | ARAP1,AVIL,CAPG,CAPZB,CHMP2A,CORO1B,CORO2B,DMTN,FGF13,FNIP1,GMFG,HGF,INPP5K,INSIG1,KANK1,KDM5A,MAP1B,MAP2,MTM1,MYADM,PINK1,PRKN,RAB7A,SMG6,SPEF1,SPTBN1,SWAP70,TBC1D7,TINF2,TRIM54,TSC2,TTBK2,UBE2B,VAT1,WASHC2C |
| GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 177 | 23 | ARAP1,AUTS2,BCAS3,C15orf62,CAPZB,CDC42,CDC42EP2,CYFIP1,CYLD,DMTN,EPS8L1,EPS8L2,HRG,KANK1,MARK4,PLEKHM1,RHOG,RHOQ,TAPT1,TBC1D7,TGFBR1,WASL,WDPCP |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1229 | 1224 | 70 | ABRAXAS1,ADAM17,AKAP9,APP,ATP2B4,CCNDBP1,CCNG1,CCNI,CCNYL2,CDC42,CDK19,CDK2AP2,CEP295NL,CETN2,CHMP1B,CHMP2A,CSNK1D,CTDSP2,CTNNB1,CUL7,CYLD,DAB2IP,DACT1,DCTN2,DHCR24,DUSP3,DYNC1H1,DYNLT3,ERCC6,FAP,FBXL12,FOXO4,GPNMB,HBP1,HECA,ILK,ING4,INSR,IQGAP1,ITGB1,LAMTOR3,LATS2,MADD,MARK4,NEK11,NOTCH2,NR4A1,OFD1,PPP2R5B,RHOA,RPS27L,RRAGC,SDCBP,SH3GLB1,SIRT2,SKIL,SKP1,STAT5B,SVIL,TAOK3,TGFBR1,TIMP2,TOP2B,TP53INP1,TRIM21,TRIM35,TSC2,UBE2B,ZFHX3,ZFYVE26 |
| GO_CELLULAR_LIPID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 212 | 25 | ABHD2,ACAT1,ACAT2,ACOT8,ACOX1,AKR1C3,APOC1,DECR1,EHHADH,GPCPD1,HADHA,HADHB,IDH1,LPIN1,LPIN2,LRP1,NEU1,PHYH,PLA2G15,PNPLA2,PNPLA6,PSAP,SGPL1,SIRT2,SMPD1 |
| GO_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 320 | 31 | ADCY2,ASS1,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CRK,CYFIP1,FOXO4,GNAI2,GSK3B,HDAC5,INPP5K,INSR,KANK1,LEPROT,LPIN1,LPIN2,MAP1B,MYO1C,NR4A1,PCSK9,RAB31,RAB8B,RHOQ,SORBS1,STAT5B,TSC2,WDTC1 |
| GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 378 | 34 | AVIL,BAIAP2,CSNK1D,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,GDI1,GRN,HGF,ILK,IQGAP1,LRP1,MACF1,MAP1B,MAP2K2,MDK,NCOA1,NRCAM,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,SCARB2,SKIL,SPAG9,TIMP2 |
| GO_REGULATION_OF_PROTEIN_TARGETING | 0.0e+00 | 0.0e+00 | 1229 | 81 | 16 | ATG13,CEMIP,CHP1,DMTN,GDI1,INPP5K,KCNE1,LEPROT,MIEF2,MYO1C,NPEPPS,NUCB1,PINK1,PRKN,SH3GLB1,VPS11 |
| GO_POSITIVE_REGULATION_OF_AUTOPHAGY | 0.0e+00 | 0.0e+00 | 1229 | 120 | 19 | AMBRA1,CALCOCO2,DCN,GSK3B,HMOX1,LRSAM1,OPTN,PINK1,PIP4K2C,PRKN,SH3GLB1,SPTLC1,STING1,TMEM59,TP53INP1,TP53INP2,TRIM21,TSC2,ULK1 |
| GO_BLOOD_VESSEL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 686 | 48 | ACVR1,APOD,BCAS3,CALCRL,CDC42,CHI3L1,CLIC4,CSPG4,CTNNB1,CUL7,CXCR4,DAB2IP,DCN,DYSF,EFNA1,EIF2AK3,ESM1,FAP,FOXO4,FZD8,GLUL,GPNMB,GRN,HDAC5,HGF,HIF3A,HMOX1,HRG,HTATIP2,ITGAV,ITGB1,JAK1,KLF2,LRP1,MDK,MFGE8,NOS3,NOTCH2,NR4A1,NRCAM,PRCP,RHOA,RRAS,SGPL1,SLC12A6,SMAD7,TGFBR1,ZMIZ1 |
| GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 181 | 23 | ATG13,ATP13A2,DCN,FNIP1,GSK3B,HGF,LEPROT,MIEF2,MOAP1,NPEPPS,OPTN,PINK1,PRKN,RHOT1,SH3GLB1,SQSTM1,STAT2,TMEM102,TSC2,VAT1,VPS11,YWHAZ,ZNF205 |
| GO_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1229 | 1005 | 61 | ACTG1,APP,ASS1,C1S,CALCOCO2,CAMK2D,CDC42,CDC42EP2,CRK,CTSB,CYLD,DAB2IP,FCER1G,GBP2,GRAMD4,GRN,HK1,IFI35,IFIT3,IGHV3-74,IRF9,JAK1,LGALS3,LY96,LYST,MAPKAPK2,MICA,MST1R,MYO1C,NCF2,NLRP10,OPTN,PJA2,RAB43,RFTN1,RTN4,SERINC3,SERINC5,SHFL,SIRPA,SIRPB1,SIRT2,SKP1,SLAMF6,SLC26A6,SPON2,STAT2,STAT5B,STING1,STX8,STXBP2,TANK,TBKBP1,TNFRSF14,TOLLIP,TRAF6,TRIM21,TRIM35,VIM,VNN1,WDFY1 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1673 | 86 | ACOT8,AGO4,AKR1C3,APOC1,ARID5B,ATP2B4,ATXN1,CDYL2,CIC,CTNNB1,CTNS,CUX1,DAB2,DAB2IP,DACT1,DEDD2,EAPP,EFNA1,EIF2AK3,FNIP1,FOXO4,FRK,GLIS2,GSK3B,HCFC2,HDAC5,HES6,IGBP1,ING4,INPP5K,INSIG1,ITGAV,JDP2,KDM4A,KDM5A,KDM5B,KLF11,KLF12,KLF2,LBH,LMCD1,MAFK,MAP3K10,MOSPD1,MST1,MXD4,NCOR2,NOTCH2,NRIP1,PBXIP1,PHF12,PHF21A,PKIG,PRDX5,PRKN,PSEN1,RASD1,RHOA,S100A11,SCX,SHFL,SIRPA,SIRT2,SKIL,SMAD7,SMARCAL1,SNX6,SQSTM1,TCP10L,TINF2,TMEM59,TNFSF4,TRAF6,TRPV4,TSC22D4,TSHZ3,UBE2B,UBR2,WDTC1,ZBTB4,ZFHX2,ZFHX3,ZHX2,ZNF205,ZNF281,ZNF425 |
| GO_RESPONSE_TO_LIPID | 0.0e+00 | 0.0e+00 | 1229 | 930 | 58 | AACS,ABHD2,ABR,ACSL1,ADAM17,ADCY2,ADH5,AKAP13,AKR1C3,ARNT2,ASS1,CALCOCO1,CDK19,CREBRF,CTNNB1,DAB2,DAB2IP,DCN,EEF2,FBXO32,FIBIN,GRAMD1A,HDAC5,HMGCS1,HSD17B2,IDH1,IGF2R,INSIG1,LBH,LITAF,LY96,MAP1B,MAPK1,MAPKAPK2,MDK,MSN,NCOA1,NCOA4,NCOR2,NOS3,NQO1,NR4A1,NRIP1,OTUD5,PLPP1,RHOA,RNF14,SCD,SIRPA,SPON2,STAT5B,TGFBR1,TNFSF4,TRAF6,TRIP4,VIM,WBP2,WNT5B |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 553 | 42 | ABRAXAS1,AKAP9,BCAS3,CCSER2,CDK2AP2,CEP126,CEP295NL,CETN2,CHMP1B,CHMP2A,CHP1,CSNK1D,CTNNB1,CUL7,CYLD,DCTN2,DST,DYNC1H1,FGF13,GABARAP,GOLGA2,GOLGA8N,GSK3B,ITGB1,KIZ,MAP1B,MAP2,MAP7D3,MARK4,NCKAP5L,PARD3B,RHOA,RP1L1,RSPH9,SIK3,SPEF1,TPGS1,TRIM54,TRPV4,TTBK2,TTLL3,UBE2B |
| GO_PHAGOCYTOSIS | 0.0e+00 | 0.0e+00 | 1229 | 364 | 33 | ABI1,ABR,ACTG1,ANXA11,ARPC3,BAIAP2,CDC42,CDC42SE1,CDC42SE2,CRK,CYFIP1,DYSF,FCER1G,IGHV3-74,ITGAV,ITGB1,LRP1,MAPK1,MFGE8,MYO1C,NCF2,PIP5K1C,RAB31,RAB7A,RAPGEF1,RHOG,RUBCN,SIRPA,SIRPB1,SPON2,WASL,XKR8,XKR9 |
| GO_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 201 | 24 | AKAP9,APP,ARPC3,BAIAP2,C15orf62,CDC42,CDC42EP2,CORO1B,CYFIP1,DSTN,GMFG,LIMCH1,MAP1B,MYLK3,MYO1C,PSEN1,RHOA,RHOC,SNX9,SWAP70,TGFBR1,TRPV4,WASHC2C,WASL |
| GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 0.0e+00 | 0.0e+00 | 1229 | 537 | 41 | ARHGAP21,ATP2B4,CAMK2D,CDC42,CEMIP,CHMP1B,CHMP2A,CLN3,COPG1,CSNK1D,CTNNB1,DCTN2,DYNC1H1,EXOC4,GOLGA2,GRIN2D,HMGCR,ITGB1,ITPR2,KIFAP3,LRP1,MAP2,MCOLN1,MCOLN3,MPC2,MYO1C,NSF,PARD3B,PINK1,PRKN,PSEN1,RAB11FIP5,SNAP23,TBC1D23,TMEM38A,TRAPPC6A,TRPM4,UBE2B,WASL,WIPI1,YWHAZ |
| GO_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 98 | 17 | APOD,BCAS3,CD151,CORO2B,DMTN,DST,DUSP3,HRG,IQGAP1,LAMC1,LIMCH1,LRP1,MACF1,PEAK1,RHOA,SORBS1,WDPCP |
| GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 654 | 46 | AACS,ACAT1,ACAT2,ACOT8,ACOX1,ACSL1,ACSS2,ADH5,AKR1C3,ALKBH7,APOC1,APP,ARNT,CSPG4,CYP8B1,DCN,DECR1,EHHADH,ELOVL1,HADHA,HADHB,HK1,IDH1,INSIG1,INSR,LPIN1,LPIN2,MPC2,MSMO1,OSBPL1A,OSBPL2,PC,PGM1,PGM2L1,PHYH,PLA2G15,PRXL2C,PSEN1,SCD,SCPEP1,SGPL1,SLC2A6,STARD4,UST,VNN1,WDTC1 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1047 | 62 | ABR,APP,BBS12,CST3,CTDP1,CTNNA1,CTNNB1,DAB2IP,DCN,DMTN,EFNA1,EFNB3,EIF2AK3,FGF13,FOXO4,GDI1,GPR161,GSK3B,HDAC5,HRG,HYAL3,INSIG1,ITGAV,ITGB1,JDP2,KANK1,KLF13,KLF2,LBH,LRP1,LTBP3,MAP2,MAPK1,MDK,NDFIP1,NOS3,PAX8,PINK1,PLXNA3,PMP22,PRKN,PSEN1,RHOA,RTN4,SAV1,SEMA4B,SEMA6C,SIRT2,SKIL,SMAD7,STAT5B,TCTA,TGFBR1,TNFSF4,TP53INP1,TRPM4,TRPV4,TWSG1,VASN,VAT1,VIM,ZHX2 |
| GO_GLYCEROLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 414 | 35 | ABHD2,ACSL1,APOBR,APOC1,CDIPT,CDS2,CPNE3,DGKD,GK,GPCPD1,HADHA,HADHB,INPP5K,INSIG1,IP6K1,LPIN1,LPIN2,MBOAT2,MTM1,MTMR3,PCSK9,PI4K2A,PIGG,PIP4K2C,PIP5K1C,PITPNM1,PLA2G15,PNPLA2,PNPLA6,SERINC1,SERINC2,SERINC3,SERINC5,SLC22A4,TMEM150A |
| GO_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 634 | 45 | ABCC11,ACSL1,ANO10,APOC1,AQP9,ATP10D,ATP11A,ATP9A,BEST1,CA14,CERT1,CLCN3,CLCN6,CLCN7,CLIC4,CLN3,CLN8,CTNS,LRRC8A,MPC2,NCOA1,OSBPL2,PITPNM1,PLA2R1,PSAP,PSEN1,SCARB2,SLC10A6,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC16A13,SLC17A5,SLC26A11,SLC26A4,SLC26A6,SLC2A6,SLC37A1,SLC38A2,SLC38A7,SLC43A2,SLC4A3,XKR8,XKR9 |
| GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1229 | 157 | 21 | BAIAP2,CDC42,CRK,CUL7,CUX1,CYFIP1,DBN1,DMTN,GDI1,ILK,LRP1,MACF1,MAP1B,MAP2K2,MDK,MYADM,NEDD9,PLXNA3,PTPRD,RHOA,SKIL |
| GO_RESPONSE_TO_PEPTIDE_HORMONE | 0.0e+00 | 0.0e+00 | 1229 | 436 | 36 | ADCY2,ASS1,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CRK,CYFIP1,FOXO4,GNAI2,GSK3B,HADHA,HDAC5,INPP5K,INSR,IQGAP1,KANK1,LEPROT,LPIN1,LPIN2,MAP1B,MEAK7,MYO1C,NR4A1,PCSK9,RAB31,RAB8B,RHOQ,SORBS1,STAT2,STAT5B,TRPV4,TSC2,WDTC1 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 259 | 27 | APOC1,ATP13A2,ATP2B4,CAMLG,CST3,CTSA,DAB2IP,EFNA1,FURIN,GABARAPL2,GOLGA2,HGF,HMOX1,KDM4A,MAPKAPK2,MTM1,OPHN1,OS9,PINK1,PSEN1,RGP1,RUBCN,SDCBP,SIRT2,TIMP2,TSC2,UBXN1 |
| GO_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1399 | 75 | ABRAXAS1,ACVR1,ADAM17,AGO4,AKAP9,ANXA11,APP,ARAP1,ATP2B4,CACUL1,CCNG1,CCNI,CDC42,CDK2AP2,CEP126,CEP295NL,CETN2,CHMP1B,CHMP2A,CSNK1D,CTDP1,CTDSP2,CTNNB1,CUL7,DAB2IP,DACT1,DCTN2,DHCR24,DYNC1H1,FAP,FBXL12,FOXO4,GOLGA2,GOLGA8N,GPNMB,HBP1,ILK,ING4,INSR,ITGB1,KIZ,KLF11,KLHDC8B,LAMTOR3,LATS2,LPIN1,MARK4,NEK11,NOTCH2,OFD1,OPTN,POLD4,PPP2R5B,REC8,RHOA,RHOC,RPS27L,RRAGC,SH3GLB1,SIRT2,SKIL,SKP1,SNX33,SNX9,SPTBN1,SVIL,TAOK3,TGFBR1,TOP2B,TP53INP1,UBE2B,UBR2,WASL,ZFHX3,ZFYVE26 |
| GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 224 | 25 | AKAP9,ARPC3,BAIAP2,BCAS3,C15orf62,CDC42,CDC42EP2,CORO1B,CYFIP1,DSTN,DYNC1H1,GMFG,LIMCH1,MAP1B,MYLK3,MYO1C,PLXNA3,RHOA,RHOC,SNX9,SWAP70,TGFBR1,TRPV4,WASHC2C,WASL |
| GO_ERBB_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1229 | 143 | 20 | ADAM17,APP,ARAP1,CAMLG,CDC42,CPNE3,DAB2IP,DGKD,DUSP3,EPS15,IQGAP1,ITGA1,MAPK1,MVB12B,PSEN1,PTPRR,RAB7A,RHBDF1,RTN4,SNX6 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 1187 | 67 | ABI1,ACTG1,ADAM17,APP,ARNT,ARPC3,ATP6AP1,BAIAP2,C1S,CD276,CD81,CDC42,CRK,CTSB,CYFIP1,CYLD,DAB2IP,DUSP3,DYSF,EFNB3,FCER1G,FCGRT,GNAS,GRAMD4,HK1,HMOX1,HRG,IGHV3-74,LGALS3,LY96,MADCAM1,MAP3K8,MAPK1,MAPKAPK2,MDK,MICA,MOSPD2,MYO1C,NLRP10,NOTCH2,PJA2,PROS1,PSEN1,RAPGEF1,RFTN1,RHOA,RTN4,SIRPA,SIRPB1,SKP1,SLAMF6,SPON2,STAT5B,STING1,STX7,STXBP2,SWAP70,TANK,TMEM102,TNFRSF14,TNFSF4,TRAF6,TRPV4,VNN1,WASL,WDFY1,ZMIZ1 |
| GO_REGULATION_OF_PH | 0.0e+00 | 0.0e+00 | 1229 | 101 | 17 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CHP1,CLCN3,CLIC4,CLN3,GRN,MAPK1,RAB7A,ROGDI,SLC26A4,SLC26A6,SLC4A3,TMEM165 |
| GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 0.0e+00 | 0.0e+00 | 1229 | 243 | 26 | APP,CDC42,CYLD,DAB2IP,DACT1,DUSP3,ERCC6,FZD8,HGF,HIPK3,HMGCR,IGBP1,MAP2K2,MAP3K10,MAPK1,PINK1,PJA2,PPEF2,PRKN,RAPGEF1,SDCBP,SIRPA,SPAG9,TAOK3,TRAF6,TRPV4 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 115 | 18 | AVIL,CALCOCO2,CAPG,CAPZB,DMTN,DSTN,FGF13,INSR,MAP1B,RUBCN,SHFL,SPEF1,SPTBN1,SWAP70,TRIM54,TRPV4,TTBK2,WASHC2C |
| GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1229 | 360 | 32 | APLP2,APP,CAMLG,CD109,CLN3,CLN8,CST3,CSTB,DHCR24,EFNA1,FNIP1,FURIN,GABARAPL2,GLG1,HGF,HRG,IGBP1,LRP1,MICAL1,MTM1,OPHN1,OS9,PRDX5,PROS1,PSEN1,SDCBP,SERPINB1,SERPINB6,TIMP2,TMEM59,TRIM21,UBXN1 |
| GO_REGULATION_OF_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1229 | 194 | 23 | AKAP13,CEP295NL,CHMP1B,CHMP2A,CYLD,DYNC1H1,LRSAM1,MARK4,MSN,MTM1,MTMR3,MYLK3,PINK1,PIP4K2C,PTPRD,RHOA,SDCBP,SH3GLB1,TAPT1,TBC1D12,TBC1D7,ULK1,VPS11 |
| GO_NEGATIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1229 | 534 | 40 | ABR,ANXA4,APOC1,APOD,CAMK2D,CHP1,CYFIP1,CYP51A1,DMTN,DYSF,ERP29,FRMD4A,GDI1,GNAI2,HMGCR,HMOX1,INPP5K,INSIG1,ITGAV,KCNE1,LGALS3,LRSAM1,MAP1B,NDFIP1,NOS3,OS9,PCSK9,PKIG,PLA2R1,PRKN,RAB11FIP5,RAB23,RAB7A,RHBDF1,RUBCN,SDCBP,SERPINB1,SESTD1,SIRPA,SNX33 |
| GO_MEMBRANE_DOCKING | 0.0e+00 | 0.0e+00 | 1229 | 179 | 22 | AKAP9,CETN2,CHP1,CSNK1D,DCTN2,DYNC1H1,ESYT1,ESYT2,EXOC4,EXOC6B,MARK4,MSN,NSF,OFD1,RAB7A,RAB8B,STX3,STX7,STX8,STXBP2,TTBK2,VPS11 |
| GO_MUSCLE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 470 | 37 | AKAP13,AKAP9,ANXA6,ATP2B4,CALCRL,CALD1,CAMK2D,CAMTA2,CERT1,CHRNB1,CTDP1,CXCR4,DSP,DTNA,DYSF,EEF2,FBXO32,FGF13,GAA,HMOX1,ITGA1,KCNE1,LMCD1,MYL12A,MYL12B,MYL5,MYL6,MYL6B,NOS3,P2RX6,RHOA,SMAD7,SORBS1,SYNM,TMEM38A,TRPM4,VIM |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1229 | 723 | 48 | AACS,ACAT1,ACAT2,ACOT8,ACSS2,AKR1C3,APOC1,ASS1,ATP2B4,CDA,CEMIP,CSPG4,CYB5R3,CYP51A1,CYP8B1,DCN,DHCR24,EBP,ELOVL1,ERG28,FDFT1,FDPS,GLUL,HMGCR,HMGCS1,IDI1,INSIG1,IP6K1,LSS,MSMO1,MST1,NSDHL,NT5C2,OSBPL1A,OSBPL2,PC,PGM1,PLOD2,SC5D,SCD,SERINC3,SERINC5,SMPDL3A,SPTLC1,STARD4,UPB1,UST,WDTC1 |
| GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 215 | 24 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CYFIP1,FOXO4,GNAI2,GSK3B,HDAC5,INPP5K,INSR,KANK1,LPIN1,LPIN2,MYO1C,PCSK9,RAB31,RAB8B,RHOQ,SORBS1,TSC2,WDTC1 |
| GO_DEVELOPMENTAL_CELL_GROWTH | 0.0e+00 | 0.0e+00 | 1229 | 233 | 25 | AKAP13,APP,AUTS2,CTDP1,CTNNB1,CXCR4,CYFIP1,DBN1,FGF13,GDI1,GSK3B,ILK,IQGAP1,ITGB1,LRP1,MACF1,MAP1B,MAP2,NRCAM,PLXNA3,PRKN,RTN4,SEMA4B,SEMA6C,ULK1 |
| GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 0.0e+00 | 0.0e+00 | 1229 | 327 | 30 | CD81,DAB2,FCER1G,FCHO2,FGF13,INPP5K,ITGB1,LGALS3,LRP1,MACF1,MYADM,NSF,NUMB,OPTN,RAB31,RAB8B,RHOG,RHOQ,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,TMBIM1,TMEM150A,TMEM59,TMEM88,TSPAN14,WDR19 |
| GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 289 | 28 | AVIL,BAIAP2,CUL7,CUX1,CXCR4,CYFIP1,DAB2IP,DBN1,GDI1,GRN,HGF,ILK,IQGAP1,LRP1,MACF1,MAP1B,MAP2K2,MDK,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,SCARB2,SKIL |
| GO_REGULATION_OF_PROTEIN_POLYMERIZATION | 0.0e+00 | 0.0e+00 | 1229 | 216 | 24 | AKAP9,ARPC3,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42EP2,CORO1B,CYFIP1,DBN1,DMTN,GMFG,KANK1,MAP1B,MAP2,MYADM,MYO1C,PINK1,RHOA,SNX9,SPTBN1,WASHC2C,WASL |
| GO_REGULATION_OF_SECRETION | 0.0e+00 | 0.0e+00 | 1229 | 824 | 52 | AACS,ABR,ANXA4,APBA2,ATP13A2,ATP6AP1,CHMP2A,CYP51A1,ERP29,EXOC1,FCER1G,FRMD4A,FRMD8,GALR1,GLUL,GNAI2,GNAS,GSK3B,HK1,HMGCR,HMOX1,HYAL3,IL17RA,ITPR2,KDM5B,LRP1,MDK,MICAL1,MPC2,NLRP10,NSF,PAX8,PINK1,PLA2R1,PRKN,RAB11FIP5,RAB7A,RAB8B,RAB9A,RHBDF1,RHOT1,SDCBP,SERPINB1,SPTBN1,STXBP2,STXBP5,SYT15,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4 |
| GO_RESPONSE_TO_INSULIN | 0.0e+00 | 0.0e+00 | 1229 | 271 | 27 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,CYFIP1,FOXO4,GNAI2,GSK3B,HADHA,HDAC5,INPP5K,INSR,KANK1,LPIN1,LPIN2,MEAK7,MYO1C,PCSK9,RAB31,RAB8B,RHOQ,SORBS1,TRPV4,TSC2,WDTC1 |
| GO_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 1296 | 70 | ABI1,ACAT1,ACVR1,ADAM17,ADAMTSL2,AKR1C3,AMBRA1,ANXA4,ATP6AP2,CALB1,CAPN1,CAPNS1,CD109,CD151,CDC42,CLIC4,CTNNB1,CTSB,CXCR4,DAB2,DACT1,DSP,FN3K,FOSL2,FURIN,GPR161,GSK3B,HGF,ILK,IQGAP1,KDM5B,KIAA1109,KLF2,LBH,LGALS3,MAP2K2,MAPK1,MCOLN3,MDK,MSN,MST1,MYADM,NOTCH2,NSDHL,OPHN1,PALLD,PAX8,PSAP,PSEN1,RAPGEF1,RCN3,RHOA,RHOC,RTN4,SAV1,SCX,SHARPIN,SKIL,SMAD7,STAT5B,TAGLN,TOLLIP,TPP1,TRAF6,TRPC4AP,TSC2,VIM,WDPCP,WDR19,WNT5B |
| GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1229 | 373 | 32 | ACAN,ADAMTS4,ADAMTSL2,APP,CAPN1,CAPNS1,COL11A2,COL13A1,COL24A1,COL6A1,COL6A2,CST3,DCN,FAP,FBLN5,FURIN,ITGA1,ITGA7,ITGAV,ITGB1,LAMC1,LRP1,MADCAM1,MATN3,MEGF9,NID1,PLOD2,SCUBE3,SCX,TGFBR1,TIMP2,VIPAS39 |
| GO_NEURON_PROJECTION_EXTENSION | 0.0e+00 | 0.0e+00 | 1229 | 168 | 21 | AUTS2,CTNNB1,CXCR4,CYFIP1,DBN1,GDI1,GSK3B,ILK,IQGAP1,ITGB1,LRP1,MACF1,MAP1B,MAP2,NRCAM,PLXNA3,PRKN,RTN4,SEMA4B,SEMA6C,ULK1 |
| GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 237 | 25 | ABR,AKAP13,ARHGEF12,ARHGEF6,AUTS2,CDC42SE1,CDC42SE2,CRK,CYTH1,CYTH2,DAB2IP,EPS8L1,EPS8L2,ITGB1,KANK1,KCTD10,MADD,NOTCH2,OPHN1,PSD4,RAPGEF1,SHOC2,SQSTM1,TIAM2,TIMP2 |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1229 | 459 | 36 | AACS,ATG13,ATP13A2,BCAS3,CD81,CDC42,CEMIP,CHP1,CORO2B,EXOC1,FRMD4A,FRMD8,GLUL,GSK3B,HK1,IL17RA,LEPROT,LRP1,MAPK1,MDK,MIEF2,MPC2,MYO1C,NLRP10,NPEPPS,PINK1,PRR5L,PSEN1,SH3GLB1,SPTBN1,TNFRSF14,TNFSF4,TRPM4,TRPV4,VPS11,YWHAZ |
| GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1229 | 335 | 30 | AKR1C3,AMBRA1,BAIAP2,CASTOR2,CASTOR3,EIF2AK3,FNIP1,GABARAP,GABARAPL2,GLUL,HMOX1,LAMP2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MAPK1,MTMR3,NCOA1,PCSK9,RRAGC,SCX,SH3GLB1,SLC38A2,TRPM4,UCN2,ULK1,WDR45,WDR59,WIPI1,ZFYVE1 |
| GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1229 | 376 | 32 | ACVR1,APBA2,ARHGDIG,ARNT,ARNT2,ATP11A,CERT1,CMIP,CTNNB1,DBN1,HSD17B2,INPP5K,ITGB1,KLF2,MAN2A1,MAPK1,NCOA1,NOS3,NOTCH2,NSDHL,PTPRR,RTN4,SKIL,SLC25A34,SMIM14,TAPT1,TGFBR1,TRAF6,UBE2B,WDR19,WDTC1,ZMIZ1 |
| GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1229 | 204 | 23 | ABR,AKAP13,ARHGAP5,ARHGDIG,ARHGEF12,ARHGEF6,C15orf62,CDC42,CDC42EP2,CDC42SE1,CDC42SE2,EPS8L1,EPS8L2,ITGB1,KANK1,KCTD10,OPHN1,RHOA,RHOC,RHOG,RHOQ,RHOT1,TIAM2 |
| GO_AUTOPHAGOSOME_MATURATION | 0.0e+00 | 0.0e+00 | 1229 | 39 | 11 | CALCOCO2,CLN3,GABARAP,GABARAPL2,LAMP2,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MCOLN1,RUBCN,SNX14 |
| GO_CELL_GROWTH | 0.0e+00 | 0.0e+00 | 1229 | 483 | 37 | ADAM17,AKAP13,APP,AUTS2,CAMK2D,CDA,CDC42,CTDP1,CTNNB1,CXCR4,CYFIP1,DBN1,DNAJB2,FBLN5,FGF13,GDI1,GSK3B,HRG,ILK,IQGAP1,ITGB1,KIAA1109,LRP1,MACF1,MAP1B,MAP2,NRCAM,PLXNA3,PRKN,RHOA,RTN4,SDCBP,SEMA4B,SEMA6C,SERTAD3,TGFBR1,ULK1 |
| GO_SELECTIVE_AUTOPHAGY | 0.0e+00 | 0.0e+00 | 1229 | 49 | 12 | AMBRA1,ATG13,CALCOCO2,LRSAM1,OPTN,PINK1,PRKN,RAB7A,SPTLC1,SQSTM1,STING1,TSC2 |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1229 | 1071 | 61 | ABR,ACAN,ACVR1,ALX3,ANXA6,ARID5B,CALB1,CAPN1,CDC42,CERT1,COL13A1,COL6A1,COL6A2,CTNNA1,CTNNB1,DAB2,DACT1,DCN,DSP,EFNA1,EXOC4,GAA,GLG1,GNAS,HGF,ILK,INSIG1,INSR,KDM5B,LAMC1,LTBP3,MAN2A1,MAP2K2,MAPK1,MATN3,MDK,MEGF9,MSN,NOS3,NOTCH2,PAX8,PSEN1,RAB23,RHOA,ROGDI,RTN4,SAV1,SCX,SGPL1,SMAD7,TGFBR1,THBS3,TRAF6,TREH,TRPV4,TWSG1,UBE4B,WDPCP,WDR19,ZHX2,ZMIZ1 |
| GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 1.0e-07 | 1229 | 401 | 33 | CD276,CD81,CDC42,CRK,CYLD,DMTN,DYSF,EFNB3,GSK3B,HRG,ILK,IQGAP1,ITGAV,KIFAP3,MAP3K8,MDK,MYADM,NEDD9,NFAT5,NID1,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,STX3,TMEM102,TNFRSF14,TNFSF4,TRAF6,VNN1,ZFHX3,ZMIZ1 |
| GO_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | 0.0e+00 | 1.0e-07 | 1229 | 157 | 20 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CHP1,CLCN3,CLIC4,CLN3,GNAI2,GRN,MAPK1,RAB7A,ROGDI,SLC12A4,SLC12A6,SLC26A4,SLC26A6,SLC4A3,TMEM165 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 0.0e+00 | 1.0e-07 | 1229 | 207 | 23 | ATG13,BCAS3,CD81,CDC42,CEMIP,CHP1,DAB2,DYNC1H1,FCER1G,GSK3B,LEPROT,MAP2,MAPK1,MIEF2,MSN,MYO1C,NPEPPS,PINK1,PRKN,PRR5L,PSEN1,SH3GLB1,VPS11 |
| GO_RECEPTOR_MEDIATED_ENDOCYTOSIS | 0.0e+00 | 1.0e-07 | 1229 | 320 | 29 | AAK1,APOC1,BTBD8,CALCRL,CAP1,CD63,CD81,CLN3,CLTCL1,DAB2,EPS15,FCER1G,FCHO2,IGF2R,INSR,ITGB1,LMBR1L,LRP1,NUMB,OPHN1,PCSK9,PDLIM7,PIP5K1C,PLA2R1,RAB31,SCARB2,SDCBP,SNX9,WASL |
| GO_GOLGI_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1229 | 142 | 19 | AKAP9,ARHGAP21,BCAS3,CDC42,CSNK1D,CUL7,GOLGA2,GOLGA8N,GOLGB1,MAP2K2,MAPK1,OPTN,PDE4DIP,PI4K2A,PLEKHM2,RAB43,TMED4,TRAPPC8,YWHAZ |
| GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 0.0e+00 | 1.0e-07 | 1229 | 209 | 23 | APOD,BCAS3,CDC42,CORO2B,CRK,DMTN,DUSP3,GSK3B,HRG,ILK,IQGAP1,KANK1,LIMCH1,LRP1,MACF1,MDK,MYADM,NEDD9,NID1,PEAK1,RHOA,WASHC2C,WDPCP |
| GO_TUBE_MORPHOGENESIS | 0.0e+00 | 1.0e-07 | 1229 | 928 | 55 | ACVR1,APOD,BCAS3,CALCRL,CDC42,CHI3L1,CLIC4,CSPG4,CTNNB1,CUL7,CXCR4,DAB2IP,DACT1,DCN,DYSF,EFNA1,EIF2AK3,ESM1,FAP,FOXO4,FZD8,GLUL,GPNMB,GRN,HDAC5,HGF,HIF3A,HMOX1,HRG,HTATIP2,ILK,ITGAV,ITGB1,JAK1,KDM5B,KLF2,LRP1,MDK,MFGE8,NOS3,NOTCH2,NR4A1,NRCAM,PAX8,PRCP,PSEN1,RHOA,RRAS,SGPL1,SLC12A6,SMAD7,TGFBR1,TRAF6,TSC2,ZMIZ1 |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 0.0e+00 | 1.0e-07 | 1229 | 62 | 13 | APOD,CHP1,DMTN,GDI1,HMOX1,INPP5K,INSIG1,KCNE1,MAP1B,OS9,PCSK9,PKIG,RAB23 |
| GO_ACTIN_FILAMENT_POLYMERIZATION | 0.0e+00 | 1.0e-07 | 1229 | 177 | 21 | ARPC3,AVIL,BAIAP2,C15orf62,CAPG,CAPZB,CDC42EP2,CORO1B,CYFIP1,DBN1,DMTN,GMFG,KANK1,MYADM,MYO1C,RHOA,SNX9,SPTBN1,WASHC2C,WASHC3,WASL |
| GO_RECEPTOR_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1229 | 195 | 22 | ARAP1,CALCRL,CAMLG,CAPN1,CD63,CD81,EPS15,FCER1G,FURIN,ITGAV,ITGB1,LRP1,NSF,NUMB,OPHN1,OPTN,PCSK9,PSEN1,RAB31,REP15,SDCBP,SH3GLB1 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 1229 | 1280 | 68 | ARID5B,ATXN1,CDYL2,CIC,CTNNB1,CUX1,DAB2,DAB2IP,DACT1,DEDD2,EAPP,EFNA1,FNIP1,FOXO4,FRK,GLIS2,HCFC2,HDAC5,HES6,IGBP1,ING4,INPP5K,JDP2,KDM4A,KDM5A,KDM5B,KLF11,KLF12,KLF2,LBH,LMCD1,MAFK,MAP3K10,MOSPD1,MXD4,NCOR2,NOTCH2,NRIP1,PBXIP1,PHF12,PHF21A,PKIG,PRDX5,PRKN,PSEN1,RASD1,SCX,SIRT2,SKIL,SMAD7,SNX6,SQSTM1,TCP10L,TNFSF4,TRAF6,TRPV4,TSC22D4,TSHZ3,UBE2B,UBR2,WDTC1,ZBTB4,ZFHX2,ZFHX3,ZHX2,ZNF205,ZNF281,ZNF425 |
| GO_CELL_CELL_SIGNALING_BY_WNT | 0.0e+00 | 1.0e-07 | 1229 | 521 | 38 | AGO4,APP,ATP6AP2,CALCOCO1,CDC42,CSNK1D,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,FOXL1,FRAT1,FZD8,GSK3B,HBP1,IGFBP6,ILK,KANK1,LATS2,LMBR1L,LRP1,LRRK1,MACF1,MDK,NID1,PPM1N,PRKN,PSEN1,RAPGEF1,RHOA,RNF146,SKP1,TMEM88,TRPM4,TSC2,UBE2B,WNT5B |
| GO_LIPID_CATABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1229 | 328 | 29 | ABHD2,ACAT1,ACAT2,ACOT8,ACOX1,AKR1C3,APOC1,DECR1,EHHADH,GPCPD1,HADHA,HADHB,HSD17B11,IDH1,LPIN1,LPIN2,LRP1,NEU1,PHYH,PLA2G15,PLD3,PNPLA2,PNPLA6,PNPLA7,PSAP,RAB7A,SGPL1,SIRT2,SMPD1 |
| GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 1229 | 270 | 26 | ACAT2,ACOT8,AKR1C3,CTNS,CYB5R3,CYP51A1,CYP8B1,DHCR24,EBP,ERG28,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,INSIG1,IP6K1,LSS,MSMO1,NSDHL,OSBPL1A,OSBPL2,SC5D,SCD,SPTLC1,STARD4 |
| GO_REGULATION_OF_LEUKOCYTE_MIGRATION | 0.0e+00 | 1.0e-07 | 1229 | 197 | 22 | ABR,ADAM17,APOD,APP,CD81,CRK,DYSF,HMOX1,LGALS3,MADCAM1,MDK,MOSPD2,MSN,MST1,MTUS1,RHOA,RHOG,SWAP70,TMEM102,TNFRSF14,TRPV4,WASL |
| GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 1.0e-07 | 1229 | 233 | 24 | APP,AUTS2,CTNNB1,CXCR4,CYFIP1,DBN1,FGF13,GDI1,GSK3B,ILK,IQGAP1,ITGB1,KDM5B,LRP1,MACF1,MAP1B,MAP2,NRCAM,PLXNA3,PRKN,RTN4,SEMA4B,SEMA6C,ULK1 |
| GO_LEUKOCYTE_MIGRATION | 0.0e+00 | 1.0e-07 | 1229 | 502 | 37 | ABR,ADAM17,APOD,APP,CD81,CDC42,CRK,CXCR4,DYSF,FCER1G,GLG1,HMOX1,IL17RA,ITGA1,ITGAV,ITGB1,LGALS3,LYST,MADCAM1,MDK,MOSPD2,MSN,MST1,MTUS1,PIP5K1C,PROS1,RHOA,RHOG,SDC2,SIRPA,STAT5B,SWAP70,TMEM102,TNFRSF14,TRPM4,TRPV4,WASL |
| GO_PLASMA_MEMBRANE_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1229 | 104 | 16 | ANXA6,BAIAP2,CXCR4,DMKN,DYSF,OSBPL2,PLEKHM2,PSAP,SH3GLB1,SNX33,SNX9,SPTBN1,TLCD2,WASL,XKR8,XKR9 |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 0.0e+00 | 1.0e-07 | 1229 | 622 | 42 | AGO4,APP,ATP6AP2,BAIAP2,CALCOCO1,CDC42,CHRNB1,CSNK1D,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,FOXL1,FRAT1,FZD8,GRIN2D,GSK3B,HBP1,IGFBP6,ILK,KANK1,LATS2,LMBR1L,LRP1,LRRK1,MACF1,MDK,NID1,P2RX6,PPM1N,PRKN,PSEN1,RAPGEF1,RHOA,RNF146,SKP1,TMEM88,TRPM4,TSC2,UBE2B,WNT5B |
| GO_CONNECTIVE_TISSUE_DEVELOPMENT | 0.0e+00 | 1.0e-07 | 1229 | 274 | 26 | AACS,ACAN,ACAT1,ANXA6,ARID5B,CHI3L1,COL11A2,COL6A1,COL6A2,CTNNB1,EIF2AK3,EVC,GLG1,GNAS,HYAL3,LTBP3,MATN3,MDK,SCX,SLC39A13,TAPT1,TGFBR1,THBS3,TRPM4,TRPV4,WNT5B |
| GO_MULTIVESICULAR_BODY_SORTING_PATHWAY | 0.0e+00 | 1.0e-07 | 1229 | 34 | 10 | CHMP1B,CHMP2A,DENND10,LEPROT,LYST,RILP,RUBCN,TMEM50A,TMEM50B,UBXN6 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 0.0e+00 | 2.0e-07 | 1229 | 649 | 43 | ABI1,ACVR1,ALX3,AMBRA1,APBA2,ARHGDIG,ARNT,ARNT2,ATP11A,ATP6AP2,CERT1,CMIP,CTNNB1,DACT1,DBN1,GNAS,GPR161,HSD17B2,INPP5K,ITGB1,KLF2,MAN2A1,MAPK1,NCOA1,NOS3,NOTCH2,NSDHL,PSEN1,PTPRR,RTN4,SCX,SKIL,SLC25A34,SMIM14,STOX2,TAPT1,TGFBR1,TRAF6,TSC2,UBE2B,WDR19,WDTC1,ZMIZ1 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1229 | 1029 | 58 | ABI1,ABR,ACVR1,ALX3,AMBRA1,APBA2,ARHGDIG,ARNT,ARNT2,ATP11A,ATP6AP2,CERT1,CMIP,COL6A1,CTNNB1,DACT1,DBN1,EFNA1,EXOC4,GNAS,GPR161,HSD17B2,INPP5K,INSIG1,INSR,ITGA7,ITGAV,ITGB1,KLF2,MAN2A1,MAPK1,MYADM,NCOA1,NOS3,NOTCH2,NSDHL,PAX8,PSEN1,PTPRR,RTN4,SCX,SKIL,SLC25A34,SMIM14,STOX2,TAPT1,TBC1D23,TGFBR1,TRAF6,TSC2,TWSG1,TXNRD1,UBE2B,WDPCP,WDR19,WDTC1,ZMIZ1,ZNF281 |
| GO_ENDOSOME_TRANSPORT_VIA_MULTIVESICULAR_BODY_SORTING_PATHWAY | 0.0e+00 | 2.0e-07 | 1229 | 26 | 9 | CHMP1B,CHMP2A,DENND10,LEPROT,LYST,RILP,TMEM50A,TMEM50B,UBXN6 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 2.0e-07 | 1229 | 532 | 38 | AACS,ACAT1,ACO1,ACOX1,ACSS2,ADH5,APP,ARNT,CAVIN3,COX6A1,COX6C,GAA,GNAS,GSK3B,HK1,IDH1,INPP5K,INSR,MT-ATP6,MT-ATP8,MT-ND2,MT-ND5,MT-ND6,NCF2,NQO1,PGLS,PGM1,PGM2L1,PINK1,PPP1R3F,PRXL2C,PSEN1,RBKS,RHOA,SLC2A6,SORBS1,TRPV4,TXNRD1 |
| GO_MITOTIC_CELL_CYCLE | 0.0e+00 | 2.0e-07 | 1229 | 1030 | 58 | ABRAXAS1,ACVR1,ADAM17,AKAP9,APP,CACUL1,CCNG1,CCNI,CDC42,CDK2AP2,CEP126,CETN2,CHMP1B,CHMP2A,CLTCL1,CSNK1D,CTDP1,CTDSP2,CTNNB1,CUL7,CYLD,DACT1,DCTN2,DUSP3,DYNC1H1,DYNLT3,FAP,FBXL12,FOXO4,GOLGA2,GPNMB,HECA,HGF,INSR,IQGAP1,ITGB1,KLF11,KLHDC8B,LATS2,LPIN1,NEK11,OFD1,OPTN,RHOA,RHOC,RPS27L,SDCBP,SIRT2,SKP1,SNX33,SNX9,SPTBN1,STAT5B,TAOK3,TIMP2,TOP2B,TRIM35,ZFYVE26 |
| GO_HEAD_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1229 | 774 | 48 | ABR,ACAT1,APOD,APP,ARID5B,ARNT2,ATP2B4,ATP6AP2,ATXN1,BAIAP2,CDC42,CIC,CRK,CSNK1D,CTNNB1,CTNS,CXCR4,DAB2IP,FGF13,GRIN2D,GSK3B,HMGCS1,ITGB1,LRP1,MAP2K2,MAPK1,MDK,NCOA1,NUMB,OPHN1,PITPNM1,PLXNA3,PSEN1,RHOA,ROGDI,RRAS,RTN4,SCX,SGPL1,SHARPIN,SIRT2,SLC38A2,SYNGR3,TBC1D23,TOP2B,TTBK2,TWSG1,ZFHX3 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1229 | 1470 | 74 | ARID5B,ATXN1,CDA,CDYL2,CIC,CTNNB1,CUX1,DAB2,DAB2IP,DACT1,DEDD2,EAPP,EFNA1,ERCC6,FNIP1,FOXO4,FRK,GLIS2,HCFC2,HDAC5,HES6,IGBP1,ING4,INPP5K,JDP2,KDM4A,KDM5A,KDM5B,KLF11,KLF12,KLF2,LBH,LMCD1,MAFK,MAP3K10,MAPKAPK2,MOSPD1,MXD4,NCOR2,NDFIP1,NOTCH2,NRIP1,PBXIP1,PHF12,PHF21A,PKIG,PRDX5,PRKN,PSEN1,RASD1,SCX,SIRT2,SKIL,SMAD7,SMG6,SNX6,SQSTM1,TCP10L,TINF2,TNFSF4,TRAF6,TRPV4,TSC22D4,TSHZ3,UBE2B,UBR2,WDTC1,ZBTB4,ZFHX2,ZFHX3,ZHX2,ZNF205,ZNF281,ZNF425 |
| GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 2.0e-07 | 1229 | 750 | 47 | APP,BBS12,CTDP1,CTNNA1,CTNNB1,DAB2IP,DMTN,EFNA1,EFNB3,FGF13,FOXO4,GDI1,GSK3B,HDAC5,INSIG1,ITGAV,ITGB1,JDP2,KANK1,KLF13,LBH,LRP1,LTBP3,MAP2,MAPK1,MDK,PLXNA3,PMP22,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,SIRT2,SKIL,SMAD7,STAT5B,TCTA,TGFBR1,TNFSF4,TP53INP1,TRPM4,TRPV4,TWSG1,VASN,VIM,ZHX2 |
| GO_ENDOSOME_ORGANIZATION | 0.0e+00 | 2.0e-07 | 1229 | 79 | 14 | ALS2CL,CHMP1B,CHMP2A,CLCN3,PI4K2A,PRKN,RAB5B,RAB7A,RILP,SCARB2,SNX33,SQSTM1,TMEM127,VPS11 |
| GO_PEPTIDYL_SERINE_MODIFICATION | 0.0e+00 | 2.0e-07 | 1229 | 319 | 28 | AKAP9,APP,ATP2B4,CAMK2D,CREBL2,CSNK1D,DCN,DMTN,EIF2AK3,ERCC6,FNIP1,GALNT3,GSK3B,HGF,HIPK3,ILK,INPP5K,LATS2,MAP2K2,MAP3K10,MAPK1,MAPKAPK2,PINK1,SMAD7,STK38L,TGFBR1,TTBK2,ULK1 |
| GO_LIPID_MODIFICATION | 0.0e+00 | 2.0e-07 | 1229 | 241 | 24 | ACAT1,ACAT2,ACOT8,ACOX1,ADH5,APOC1,APOD,DECR1,DGKD,EHHADH,HADHA,HADHB,INPP5K,IP6K1,MTM1,MTMR3,PHYH,PI4K2A,PIP4K2C,PIP5K1C,PLPP1,SOAT1,STARD4,TMEM150A |
| GO_AXON_EXTENSION | 0.0e+00 | 2.0e-07 | 1229 | 122 | 17 | AUTS2,CYFIP1,DBN1,GDI1,GSK3B,ILK,ITGB1,LRP1,MACF1,MAP1B,MAP2,NRCAM,PLXNA3,RTN4,SEMA4B,SEMA6C,ULK1 |
| GO_REGULATION_OF_GROWTH | 0.0e+00 | 2.0e-07 | 1229 | 680 | 44 | ADAM17,APP,CAMK2D,CDA,CDC42,CTDP1,CXCR4,CYFIP1,DAB2IP,DBN1,DNAJB2,FBLN5,FGF13,GDI1,GSK3B,HRG,ILK,ING4,INSR,KCTD21,KIAA1109,LATS2,LRP1,MACF1,MAP1B,MAP2,MAPK1,MTM1,NEDD9,NOTCH2,NRCAM,PLXNA3,PRKN,RFTN1,RHOA,RTN4,SAV1,SDCBP,SEMA4B,SEMA6C,SERTAD3,SGPL1,STAT5B,TGFBR1 |
| GO_ORGANIC_ANION_TRANSPORT | 0.0e+00 | 2.0e-07 | 1229 | 492 | 36 | ABCC11,ACSL1,APOC1,AQP9,ATP10D,ATP11A,ATP9A,CA14,CERT1,CLN3,CLN8,CTNS,LRRC8A,MPC2,NCOA1,OSBPL2,PITPNM1,PLA2R1,PSAP,PSEN1,SCARB2,SLC10A6,SLC13A1,SLC15A4,SLC16A13,SLC17A5,SLC26A4,SLC26A6,SLC2A6,SLC37A1,SLC38A2,SLC38A7,SLC43A2,SLC4A3,XKR8,XKR9 |
| GO_ESTABLISHMENT_OF_CELL_POLARITY | 0.0e+00 | 2.0e-07 | 1229 | 138 | 18 | BCAS3,CDC42,CRK,CYTH1,FAM89B,FGF13,FRMD4A,GSK3B,ITGB1,KANK1,MAP1B,MAP2,MSN,OPHN1,PARD3B,RHOA,UST,WDPCP |
| GO_PROTEIN_COMPLEX_OLIGOMERIZATION | 0.0e+00 | 2.0e-07 | 1229 | 493 | 36 | ACAT1,AHNAK,ANXA6,CDA,CHMP2A,CHP1,CTNNA1,DECR1,DGKD,EIF2AK3,FCER1G,GLUL,GOLGA2,HMGCR,HMOX1,ILK,INSR,KCTD10,KCTD21,LRRC8A,MCOLN1,MICU1,MIEF2,OSBPL2,P2RX6,RHOC,SCUBE3,SH3GLB1,SHARPIN,SNX9,SQSTM1,STING1,TRIM21,TRPM4,TRPM7,UPB1 |
| GO_MUSCLE_CONTRACTION | 0.0e+00 | 2.0e-07 | 1229 | 362 | 30 | AKAP9,ANXA6,ATP2B4,CALCRL,CALD1,CAMK2D,CERT1,CHRNB1,CXCR4,DSP,DTNA,DYSF,EEF2,FGF13,GAA,ITGA1,KCNE1,MYL12A,MYL12B,MYL5,MYL6,MYL6B,P2RX6,RHOA,SMAD7,SORBS1,SYNM,TMEM38A,TRPM4,VIM |
| GO_PEPTIDYL_THREONINE_MODIFICATION | 0.0e+00 | 2.0e-07 | 1229 | 123 | 17 | ACVR1,APP,CAMK2D,CEMIP,CHI3L1,DMTN,GALNT3,GSK3B,HIPK3,INPP5K,MAP3K10,MAPK1,PPEF2,SIRT2,SMAD7,TGFBR1,ULK1 |
| GO_POSITIVE_REGULATION_OF_MACROAUTOPHAGY | 0.0e+00 | 2.0e-07 | 1229 | 68 | 13 | CALCOCO2,DCN,HMOX1,LRSAM1,OPTN,PINK1,PIP4K2C,PRKN,SH3GLB1,SPTLC1,STING1,TSC2,ULK1 |
| GO_MUSCLE_ORGAN_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1229 | 407 | 32 | ARID5B,ASS1,CD164,CHD2,CTDP1,CTNNB1,DCN,DSP,EEF2,EVC,FOXO4,GPCPD1,HMGCR,ITGA7,MAPK1,MTM1,MYL6,MYL6B,RHOA,SAV1,SCX,SGCB,SGCE,SIRT2,SMAD7,SRPK3,SVIL,TAGLN,TGFBR1,UBE4B,UNC45A,ZFHX3 |
| GO_FOCAL_ADHESION_ASSEMBLY | 0.0e+00 | 3.0e-07 | 1229 | 82 | 14 | APOD,BCAS3,CORO2B,DMTN,DUSP3,HRG,IQGAP1,LIMCH1,LRP1,MACF1,PEAK1,RHOA,SORBS1,WDPCP |
| GO_PROTEIN_DEPOLYMERIZATION | 0.0e+00 | 3.0e-07 | 1229 | 110 | 16 | AVIL,CAPG,CAPZB,DMTN,DSTN,FGF13,MAP1B,MICAL1,NCKAP5L,SPEF1,SPTBN1,SWAP70,TRIM54,TRPV4,TTBK2,WASHC2C |
| GO_ACTIVATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 3.0e-07 | 1229 | 96 | 15 | ABR,BCAS3,CRK,NEDD9,RABGAP1,RABGAP1L,RAPGEF1,RHOG,TBC1D12,TBC1D17,TBC1D22A,TBC1D3B,TBC1D7,TBC1D9B,USP6 |
| GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1229 | 478 | 35 | CAMLG,CSNK1D,CTNNB1,DAB2,DAB2IP,DNAJB2,FBXL12,FBXL2,GABARAPL2,GSK3B,KCTD10,LRRC29,MTM1,OPHN1,OS9,PINK1,PRKN,PSEN1,RCN3,RHBDF1,RNF103,RNF14,SDCBP,SHARPIN,SIRT2,SKP1,SMAD7,SPSB3,UBE2B,UBE2H,UBE4B,UBR2,UBXN1,UBXN6,ZER1 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 0.0e+00 | 3.0e-07 | 1229 | 96 | 15 | DAB2,ITGB1,LGALS3,LRP1,NUMB,RHOG,RHOQ,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,TMBIM1,TMEM59 |
| GO_CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | 0.0e+00 | 3.0e-07 | 1229 | 111 | 16 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CHP1,CLCN3,CLIC4,CLN3,GRN,MAPK1,RAB7A,ROGDI,SLC26A6,SLC4A3,TMEM165 |
| GO_REGULATION_OF_PROTEIN_DEPOLYMERIZATION | 0.0e+00 | 3.0e-07 | 1229 | 83 | 14 | AVIL,CAPG,CAPZB,DMTN,DSTN,FGF13,MAP1B,SPEF1,SPTBN1,SWAP70,TRIM54,TRPV4,TTBK2,WASHC2C |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1229 | 620 | 41 | APOD,APP,ARNT,B3GNT2,B3GNT9,CHI3L1,CTBS,CYB5R3,DYSF,GAA,GALNT3,GK,GSK3B,HECTD4,HK1,HYAL3,IDH1,INPP5K,INSR,MAN2A1,MAN2A2,MANBA,MST1,NAGK,NEU1,PC,PGLS,PGM1,PGM2L1,PMM1,PPP1R3F,PRKN,PRXL2C,PSEN1,RBKS,SCARB2,SLC2A5,SLC2A6,SORBS1,TREH,WDTC1 |
| GO_SKELETAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 3.0e-07 | 1229 | 526 | 37 | ABI1,ACAN,ADAMTS4,AKAP13,ALX3,ANXA6,ARID5B,ATP6AP1,CHI3L1,COL11A2,COL13A1,COL6A1,COL6A2,CTNNB1,EBP,EIF2AK3,EVC,GLG1,GNAS,HYAL3,INSIG1,LRRK1,LTBP3,MATN3,MDK,NOTCH2,PSEN1,RAB23,RHOA,SCX,SGPL1,TAPT1,TGFBR1,THBS3,TRPV4,WDR19,WNT5B |
| GO_CELLULAR_RESPONSE_TO_DRUG | 0.0e+00 | 4.0e-07 | 1229 | 436 | 33 | ADCY2,ASS1,ATP2B4,BAIAP2,CASTOR2,CASTOR3,CRK,CTNNA1,CTNNB1,CXCR4,FBXO32,GNAI2,GNAS,GSK3B,HCN3,HGF,HMOX1,ITPR2,KLF2,MAP1LC3A,MAPK1,NCOA1,NQO1,OSER1,PINK1,PRKN,PSAP,SIRPA,TMEM38A,TP53INP1,TRPM4,VIM,ZNF277 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 4.0e-07 | 1229 | 143 | 18 | CD81,CSNK1D,DAB2,DAB2IP,DACT1,DNAJB2,GSK3B,LRP1,MSN,PCSK9,PRKN,PSEN1,PTTG1IP,RNF14,SIRT2,SMAD7,VPS11,ZER1 |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1229 | 371 | 30 | APP,ATP6AP2,CSNK1D,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,FOXL1,FRAT1,GSK3B,IGFBP6,ILK,KANK1,LATS2,LMBR1L,LRP1,LRRK1,MACF1,MDK,PPM1N,PRKN,PSEN1,RAPGEF1,RNF146,TMEM88,TRPM4,TSC2,UBE2B,WNT5B |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1229 | 603 | 40 | ACVR1,ANXA6,CTNNA1,CTNNB1,CYLD,DAB2IP,DEDD2,EIF2AK3,ERCC6,ERP29,GABARAP,GNAI2,GRINA,GSK3B,HGF,HMOX1,ITGAV,LGALS3,LY96,MADD,MOAP1,NOS3,PHLDA3,PINK1,PRKN,PSEN1,PTTG1IP,RHOT1,RPS27L,SERINC3,SGPL1,SKIL,TGFBR1,TM2D1,TMBIM1,TMEM102,UBE4B,VNN1,YWHAZ,ZNF205 |
| GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 4.0e-07 | 1229 | 463 | 34 | APLP2,APOC1,APP,BCAS3,CD109,CDC42SE1,CHP1,CST3,CSTB,DAB2IP,DHCR24,FNIP1,FURIN,GMIP,GNAI2,GSK3B,HGF,HRG,IGBP1,IQGAP1,KDM5A,LGALS3,LRP1,MAP2,MICAL1,NOS3,PLA2R1,PRDX5,PROS1,SERPINB1,SERPINB6,TIMP2,UBXN1,ZFYVE1 |
| GO_POSITIVE_REGULATION_OF_PLASMA_MEMBRANE_BOUNDED_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 4.0e-07 | 1229 | 99 | 15 | ARAP1,AUTS2,BCAS3,C15orf62,CDC42,CDC42EP2,CYFIP1,EPS8L1,EPS8L2,MARK4,PLEKHM1,RHOQ,TAPT1,TGFBR1,WASL |
| GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 0.0e+00 | 5.0e-07 | 1229 | 334 | 28 | ADCY2,ATG13,CD81,CHI3L1,CRK,CSPG4,CXCR4,DAB2IP,ERCC6,ERP29,FGF13,HGF,INSR,ITGA1,LAMTOR3,MADD,MAP2K2,MAP3K10,MAP3K8,MAPK1,MAPKAPK2,PINK1,PSEN1,RAPGEF1,SPAG9,TAOK3,TGFBR1,TRAF6 |
| GO_JNK_CASCADE | 0.0e+00 | 5.0e-07 | 1229 | 216 | 22 | APP,ARHGEF6,CDC42,CYLD,DAB2IP,DACT1,DUSP3,ERCC6,FZD8,HIPK3,MAP3K10,PINK1,PJA2,PPEF2,PRKN,RAPGEF1,SDCBP,SIRPA,SPAG9,TAOK3,TRAF6,TRPV4 |
| GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | 0.0e+00 | 5.0e-07 | 1229 | 181 | 20 | APP,ARHGAP21,ARL8A,ARL8B,BBS12,CDC42,CLN3,COPG1,DST,DYNC1H1,IFT27,KIF3C,KIFAP3,LCA5,MAP1B,MAP2,MYO1C,RHOT1,WASL,WDR19 |
| GO_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ASSEMBLY | 0.0e+00 | 5.0e-07 | 1229 | 61 | 12 | APOD,BCAS3,DMTN,DUSP3,HRG,IQGAP1,LIMCH1,LRP1,MACF1,PEAK1,RHOA,WDPCP |
| GO_MONOVALENT_INORGANIC_CATION_TRANSPORT | 0.0e+00 | 6.0e-07 | 1229 | 537 | 37 | AKAP9,ATP2B4,ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CAMK2D,CD63,CHP1,CLCN3,COX6A1,COX6C,FGF13,HCN3,KCNE1,KCNK6,KLHL24,MAGED2,MT-ATP6,MT-ATP8,NOS3,NSF,PCSK9,SLC10A6,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC17A5,SLC22A4,SLC2A6,SLC38A2,SLC38A7,TMCO3,TMEM38A,TRPM4 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 6.0e-07 | 1229 | 30 | 9 | DAB2,DMTN,GDI1,INPP5K,KCNE1,NUMB,RHOQ,TMBIM1,TMEM59 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 6.0e-07 | 1229 | 564 | 38 | ACOT8,ACOX1,APOD,ATG13,CHP1,EHHADH,EPS15,HK1,IDH1,LAMP2,LEPROT,LRSAM1,MAPK1,MOAP1,NCOA4,NPEPPS,NUMB,OPHN1,PAOX,PEX6,PHYH,PINK1,PKIG,PMM1,PRKN,PSEN1,PTTG1IP,RAB23,RAB7A,RAB8B,SCARB2,SH3GLB1,SRP14,TRAPPC8,TSC2,VPS11,YWHAZ,ZFYVE16 |
| GO_MICROTUBULE_BASED_TRANSPORT | 0.0e+00 | 7.0e-07 | 1229 | 184 | 20 | APP,ARHGAP21,ARL8A,ARL8B,BBS12,CDC42,CLN3,COPG1,DST,DYNC1H1,IFT27,KIAA0556,KIF3C,KIFAP3,LCA5,MAP1B,MAP2,OFD1,RHOT1,WDR19 |
| GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 7.0e-07 | 1229 | 184 | 20 | CAPZB,EFNA1,EFNB3,FGF13,GDI1,GSK3B,HRG,KANK1,LRP1,MAP2,PLXNA3,PMP22,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,TBC1D7,TRPV4,VIM |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 7.0e-07 | 1229 | 75 | 13 | AVIL,CAPG,CAPZB,DMTN,FGF13,MAP1B,RUBCN,SPEF1,SPTBN1,SWAP70,TRIM54,TTBK2,WASHC2C |
| GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 8.0e-07 | 1229 | 185 | 20 | CAMLG,CSNK1D,DAB2,DAB2IP,DNAJB2,GABARAPL2,GSK3B,MTM1,OPHN1,OS9,PINK1,PRKN,PSEN1,RHBDF1,RNF14,SDCBP,SIRT2,SMAD7,UBXN1,ZER1 |
| GO_LEUKOCYTE_CELL_CELL_ADHESION | 0.0e+00 | 8.0e-07 | 1229 | 343 | 28 | ASS1,CD276,CD81,CDC42,CERCAM,CYLD,DUSP3,EFNB3,GPNMB,ITGB1,LGALS3,MADCAM1,MAP3K8,MDK,MSN,NDFIP1,NFAT5,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,TNFRSF14,TNFSF4,TRAF6,TWSG1,VNN1,ZMIZ1 |
| GO_METAL_ION_HOMEOSTASIS | 0.0e+00 | 8.0e-07 | 1229 | 667 | 42 | ACO1,ANXA6,APP,ATP13A2,ATP2B4,ATP6AP1,BTBD9,CALB1,CAMK2D,CEMIP,CLN3,CP,CXCR4,CYBRD1,FTH1,FTL,GALR1,GNAI2,GRIN2D,GRINA,HMOX1,ITGAV,ITPR2,LRP1,MCOLN1,MCOLN3,MICU1,NCOA4,NDFIP1,PRKN,PSEN1,SKP1,SLC12A4,SLC12A6,SLC31A2,SLC39A13,SWAP70,TMEM165,TMEM38A,TRPM4,TRPM7,TRPV4 |
| GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 8.0e-07 | 1229 | 204 | 21 | ANXA4,APOD,CHP1,CORO2B,CYP51A1,DMTN,ERP29,FRMD4A,GDI1,HMGCR,INPP5K,INSIG1,KCNE1,NDFIP1,OS9,PKIG,PRKN,RAB11FIP5,RAB23,RHBDF1,SERPINB1 |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 9.0e-07 | 1229 | 41 | 10 | APOD,CHP1,DMTN,GDI1,INPP5K,INSIG1,KCNE1,OS9,PKIG,RAB23 |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 9.0e-07 | 1229 | 547 | 37 | AVIL,BAIAP2,CSNK1D,CTNNB1,CUL7,CUX1,CXCR4,CYB5D2,CYFIP1,DAB2IP,DBN1,GDI1,GRN,HGF,ILK,IQGAP1,LRP1,MACF1,MAN2A1,MAP1B,MAP2K2,MDK,NCOA1,NRCAM,NUMB,PLXNA3,PPP2R5B,PRKN,PSEN1,PTPRD,RAPGEF1,RETREG3,RHOA,SCARB2,SKIL,SPAG9,TIMP2 |
| GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 9.0e-07 | 1229 | 120 | 16 | ADAM17,APP,ARAP1,CAMLG,CDC42,DAB2IP,DGKD,DUSP3,EPS15,IQGAP1,ITGA1,MVB12B,PSEN1,RAB7A,RHBDF1,SNX6 |
| GO_REGULATION_OF_PROTEIN_BINDING | 0.0e+00 | 9.0e-07 | 1229 | 224 | 22 | APP,CDC42,CRK,CYLD,DAB2,DAB2IP,DACT1,DNAJB2,GOLGA2,GSK3B,HDAC5,LGALS3,LRP1,MAP2,MAP2K2,PBXIP1,PCSK9,PRKN,PSEN1,STING1,TGFBR1,TTBK2 |
| GO_DENDRITE_DEVELOPMENT | 0.0e+00 | 1.0e-06 | 1229 | 244 | 23 | ABI1,APP,BAIAP2,CDC42,CRK,CUL7,CUX1,CYFIP1,DAB2IP,DBN1,EFNA1,GSK3B,ILK,IQGAP1,ITGB1,LZTS3,MAP1B,MAP2,PSEN1,PTPRD,RHOA,SDC2,WASL |
| GO_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 1.0e-07 | 1.0e-06 | 1229 | 435 | 32 | AKR1C3,APOC1,APP,ARNT,ATP2B4,CDA,CYP51A1,FDFT1,FDPS,GSK3B,HMGCR,HMGCS1,IDI1,INPP5K,INSIG1,INSR,LSS,MST1,NCOR2,NOS3,NQO1,PINK1,PPP1R3F,PRKN,PRXL2C,PSEN1,SC5D,SCD,SLC2A6,SORBS1,STARD4,WDTC1 |
| GO_REPRODUCTION | 1.0e-07 | 1.0e-06 | 1229 | 1457 | 71 | ABHD2,ACOX1,ACVR1,AGO4,AKR1C3,APP,ARID5B,ARNT,ATP2B4,BRD2,CCNI,CETN2,CLIC4,CREBRF,CRTAP,CTCFL,CTNNA1,CTNNB1,CTSB,CUL7,DCN,DHCR24,GOLGA2,HMGCS1,HSD17B2,HYAL3,IDH1,IFT27,IGF2R,INSR,ITGB1,KDM5A,KDM5B,MAGED2,MAPK1,MDK,MFGE8,MST1R,NCOA1,NCOA4,NCOR2,NOS3,NOTCH2,NRIP1,NSDHL,PLPP1,PSAP,PSG4,PSG5,PSG7,PSG9,REC8,SCX,SGPL1,SIRT2,SKIL,SLC26A6,SLC38A2,SPANXB1,STAT5B,STOX2,TGFBR1,TOP2B,TPGS1,TUT7,UBE2B,UBR2,USP9Y,VIPAS39,WDR19,ZMIZ1 |
| GO_DRUG_METABOLIC_PROCESS | 1.0e-07 | 1.1e-06 | 1229 | 600 | 39 | AACS,ACAT1,ACO1,ACOT8,ACOX1,ACSL1,ACSS2,ADH5,AHCYL2,AKR1C3,ASS1,ATP2B4,CSPG4,CTBS,CTNS,CYP2W1,DCN,ELOVL1,ETHE1,FMO4,INSR,KLF2,LMBRD1,MT-ATP6,MT-ATP8,NAGK,NOS3,NQO1,NT5C2,PAOX,PC,PINK1,PRDX5,PRKN,SAT2,SIRPA,STAT5B,UST,ZNF205 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION | 1.0e-07 | 1.1e-06 | 1229 | 227 | 22 | CAPZB,CTSD,CTSF,DCTN2,DYNC1H1,FCER1G,FCGRT,ITGAV,KIF3C,KIFAP3,MICA,NCF2,OSBPL1A,RAB32,RAB5B,RAB7A,RAB8B,RFTN1,RILP,SNAP23,TAPBPL,TRAF6 |
| GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 1.0e-07 | 1.1e-06 | 1229 | 92 | 14 | APOD,BCAS3,DMTN,DUSP3,HRG,IQGAP1,LIMCH1,LRP1,MACF1,MYO1C,PEAK1,RAPGEF1,RHOA,WDPCP |
| GO_GLAND_DEVELOPMENT | 1.0e-07 | 1.1e-06 | 1229 | 437 | 32 | AACS,ACAT1,ARHGAP5,ARID5B,ASS1,CAPN1,CDC42,CTNNB1,HGF,HMGCS1,HMOX1,IGF2R,INSR,KDM5B,LBH,MAN2A1,MAP2K2,MAPK1,MDK,MSN,MST1,NCOA1,NCOR2,NOTCH2,PAX8,PCSK9,PSAP,PSEN1,RTN4,STAT5B,TGFBR1,TWSG1 |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 1.0e-07 | 1.2e-06 | 1229 | 1235 | 63 | ABRAXAS1,ADAM17,AKAP9,APP,AQP9,ARNT,ARNT2,ATP2B4,ATP6AP1,BEST1,CAMK2D,CHI3L1,CHP1,CLCN6,CLCN7,CTNS,CXCR4,CYFIP1,DCN,DNAJC3,DYSF,EIF2AK3,ERCC6,GSK3B,HIF3A,HMGCR,HMGCS1,HMOX1,HYAL3,ITGB1,ITPR2,LRRC8A,MAP1B,MAPK1,MAPKAPK2,MCOLN1,MDK,MICA,MICU1,MT-ATP6,MT-ND5,NFAT5,NOS3,NPEPPS,NQO1,PINK1,PITPNM1,PLOD2,RAB11FIP5,RHOA,S100A13,SCX,SERPINB6,SIRT2,SLC12A6,SLC38A2,TANK,TP53INP1,TRPV4,TSC22D4,UBE2B,UBE4B,VASN |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 1.0e-07 | 1.2e-06 | 1229 | 990 | 54 | ABI1,ADAM17,AGO4,APLF,APP,ARNT,ATP6AP1,CD109,CD164,CD81,CDC42,CTNNB1,CYLD,DMTN,DNASE2,EEF2,FCER1G,FNIP1,FOXL1,FZD8,GNAS,HDAC5,HERC6,ITGB1,KLF13,KLF2,KLF6,KMT2C,LGALS3,LMBR1L,LRRC8A,LRRK1,MAP2K2,MAPK1,MDK,NDFIP1,NOTCH2,OSTM1,PSEN1,RHOA,ROGDI,RRAS,SGPL1,SLAMF6,SMAD7,STAT5B,SWAP70,TCTA,TGFBR1,TNFSF4,TRAF6,TWSG1,VNN1,ZMIZ1 |
| GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 1.0e-07 | 1.2e-06 | 1229 | 439 | 32 | AGO4,AKR1C3,ARID5B,ARNT,CTNNA1,CTNNB1,CTSB,CUL7,DCN,DHCR24,HMGCS1,HSD17B2,HYAL3,IDH1,INSR,KDM5A,KDM5B,MAPK1,NCOA1,NCOA4,NOS3,NOTCH2,NRIP1,NSDHL,PSAP,REC8,SCX,SGPL1,STAT5B,STOX2,TGFBR1,WDR19 |
| GO_REGULATION_OF_PROTEIN_STABILITY | 1.0e-07 | 1.2e-06 | 1229 | 288 | 25 | AAK1,CAMLG,CD81,CHP1,CMTM6,CREBL2,CRTAP,CTSA,DACT1,EFNA1,GRN,LAMP2,LSS,MAPK1,PEX6,PINK1,PRKN,RTN4,SAV1,SH3GLB1,SMAD7,TMEM88,TRIM21,UBE2B,VPS11 |
| GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | 1.0e-07 | 1.2e-06 | 1229 | 248 | 23 | ACVR1,ADAM17,ADAMTSL2,CD109,CRK,DAB2,FAM89B,FNDC4,FURIN,GLG1,LTBP3,RHOA,SCX,SDCBP,SKIL,SMAD7,SMAD9,SNX6,TGFBR1,TWSG1,USP9Y,VASN,ZFHX3 |
| GO_CARTILAGE_DEVELOPMENT | 1.0e-07 | 1.3e-06 | 1229 | 210 | 21 | ACAN,ANXA6,CHI3L1,COL11A2,COL6A1,COL6A2,CTNNB1,EIF2AK3,EVC,GLG1,GNAS,HYAL3,LTBP3,MATN3,MDK,SCX,TAPT1,TGFBR1,THBS3,TRPV4,WNT5B |
| GO_REGULATION_OF_ENDOCYTOSIS | 1.0e-07 | 1.3e-06 | 1229 | 210 | 21 | AAK1,APOC1,BTBD9,CD151,CD63,DAB2,LGALS3,LRP1,LRSAM1,NUMB,OPHN1,PCSK9,RAB31,RAB4B,RAB5B,RUBCN,SDCBP,SNX33,TSC2,WASL,ZFYVE16 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 1.0e-07 | 1.4e-06 | 1229 | 995 | 54 | ABR,ACAN,ACAT1,APOD,APP,ARNT2,ATP2B4,ATXN1,BAIAP2,CDC42,CIC,CLN8,CRK,CSNK1D,CTNNB1,CTNS,CXCR4,DAB2IP,FGF13,GLIS2,GRIN2D,GRN,GSK3B,HMGCS1,ITGB1,LRP1,MAP2,MAPK1,MDK,NCOA1,NRCAM,NUMB,OPHN1,PAX8,PITPNM1,PLXNA3,PRKN,PSEN1,RHOA,RNF103,ROGDI,RTN4,SHARPIN,SIRT2,SLC38A2,SYNGR3,TBC1D23,TIMP2,TOP2B,TPP1,TTBK2,TWSG1,VIM,ZFHX3 |
| GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 1.0e-07 | 1.4e-06 | 1229 | 94 | 14 | ADAM17,APP,ARAP1,CDC42,DAB2IP,DUSP3,EPS15,ITGA1,MVB12B,PSEN1,RAB7A,RHBDF1,RTN4,SNX6 |
| GO_SYNAPTIC_SIGNALING | 1.0e-07 | 1.5e-06 | 1229 | 733 | 44 | ABR,AKAP9,APBA2,APP,BAIAP2,CALB1,CHRNB1,CTNNB1,CYFIP1,DBN1,DTNA,EFNB3,EXOC4,GABARAP,GLUL,GNAI2,GRIN2D,GSK3B,ITGB1,MAP1B,MAPK1,NQO1,OPHN1,P2RX6,PCDHB10,PCDHB13,PCDHB14,PCDHB9,PINK1,PIP5K1C,PMP22,PRKN,PSEN1,PTPRD,RHOT1,SDCBP,SLC12A4,SLC12A6,SNAP23,SQSTM1,STX3,TPGS1,TPRG1L,TSHZ3 |
| GO_PH_REDUCTION | 1.0e-07 | 1.6e-06 | 1229 | 55 | 11 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CLCN3,CLIC4,CLN3,GRN,RAB7A,ROGDI |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 1.0e-07 | 1.6e-06 | 1229 | 1859 | 84 | ABTB1,ACAN,ACAT1,ACO1,ACOT8,ACSL1,ACSS2,ADCY2,AGO4,APP,ASS1,ATP2B4,B3GNT2,B3GNT9,CDA,CDS2,CEMIP,CERT1,CHP1,CHPF,CLN8,CSPG4,CTNNB1,CYFIP1,DCN,DNAJC3,EEF1A1P5,EEF2,EIF1AY,EIF2AK3,EIF4E3,ELOVL1,FOXL1,FURIN,GALNT3,GLUL,GOLGA2,ITGAV,LPIN1,LPIN2,MAN1A2,MAN2A1,MAN2A2,MAPK1,MPC2,MT-ATP6,MT-ATP8,NOS3,OPLAH,PAOX,PIGG,PINK1,PLOD2,PLPP1,PMM1,PSEN1,RHOA,RPS27L,RRBP1,SAMD8,SCD,SDC2,SECISBP2L,SERINC3,SERINC5,SGPL1,SHFL,SMPD1,SOAT1,SPTLC1,STAT5B,TMEM165,TMEM59,TRAF6,TRNAU1AP,UPB1,UST,VIM,WDR45,WIPI1,ZDHHC1,ZDHHC17,ZDHHC2,ZDHHC7 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 1.0e-07 | 1.6e-06 | 1229 | 292 | 25 | ADAM17,ADAMTSL2,ARNT,CD109,CD63,CTNNB1,CYFIP1,DAB2,DAB2IP,DCN,DSTYK,FAM89B,GLG1,HRG,ILK,MYO1C,NOTCH2,PPP2R5B,SDCBP,SKIL,SMAD7,SNX6,TGFBR1,TWSG1,VASN |
| GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH | 1.0e-07 | 1.6e-06 | 1229 | 110 | 15 | CYFIP1,DBN1,FGF13,GDI1,GSK3B,ILK,LRP1,MACF1,MAP1B,MAP2,NRCAM,PLXNA3,RTN4,SEMA4B,SEMA6C |
| GO_REGULATION_OF_VACUOLE_ORGANIZATION | 1.0e-07 | 1.7e-06 | 1229 | 44 | 10 | GRN,LRSAM1,MTM1,MTMR3,PINK1,PIP4K2C,SCARB2,SH3GLB1,TBC1D12,ULK1 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 1.0e-07 | 1.7e-06 | 1229 | 974 | 53 | ABHD2,ACOX1,ACVR1,AGO4,AKR1C3,ARID5B,ARNT,ATP2B4,BRD2,CCNI,CETN2,CRTAP,CTNNA1,CTNNB1,CTSB,CUL7,DCN,DHCR24,HMGCS1,HSD17B2,HYAL3,IDH1,IFT27,IGF2R,INSR,KDM5A,KDM5B,MAPK1,MDK,NCOA1,NCOA4,NOS3,NOTCH2,NRIP1,NSDHL,PSAP,REC8,SCX,SGPL1,SIRT2,SKIL,SLC26A6,SPANXB1,STAT5B,STOX2,TGFBR1,TPGS1,TUT7,UBE2B,UBR2,USP9Y,VIPAS39,WDR19 |
| GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 1.0e-07 | 1.8e-06 | 1229 | 25 | 8 | DAB2,DENND10,MAP2,MAP2K2,MAPK1,MSN,PRKN,VPS11 |
| GO_SPHINGOLIPID_METABOLIC_PROCESS | 1.0e-07 | 1.8e-06 | 1229 | 160 | 18 | CERT1,CLN8,CTSA,ELOVL1,ESYT1,ESYT2,NEU1,PLA2G15,PLPP1,PSAP,SAMD8,SERINC1,SERINC2,SERINC3,SERINC5,SGPL1,SMPD1,SPTLC1 |
| GO_INFLAMMATORY_RESPONSE | 1.0e-07 | 1.8e-06 | 1229 | 765 | 45 | ABR,ACVR1,APOD,APP,ASS1,CALCRL,CD81,CDK19,CHI3L1,CXCR4,CYLD,DAB2IP,DNASE1,FCER1G,FNDC4,GRN,HDAC5,HGF,HK1,HMOX1,HYAL3,IL17RA,LRP1,LY96,MAPKAPK2,MDK,MYLK3,NDFIP1,NLRP10,NOTCH2,OSMR,PJA2,PRCP,PRDX5,PSEN1,SHARPIN,SIRPA,SNAP23,STAT5B,STING1,TBC1D23,TNFSF4,TOLLIP,TRPV4,VNN1 |
| GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 1.0e-07 | 1.9e-06 | 1229 | 274 | 24 | ACVR1,CD164,CDH9,ITGB1,KIFAP3,MYADM,PALLD,PCDHB10,PCDHB13,PCDHB14,PCDHB15,PCDHB9,PCDHGA1,PCDHGA10,PCDHGA11,PCDHGA5,PCDHGA6,PCDHGA7,PCDHGA9,PCDHGB2,PCDHGB7,PCDHGC4,PTPRD,SPARCL1 |
| GO_CELLULAR_RESPONSE_TO_LIPID | 1.0e-07 | 1.9e-06 | 1229 | 615 | 39 | AACS,ABHD2,ADCY2,AKAP13,AKR1C3,ASS1,CALCOCO1,CDK19,CREBRF,CTNNB1,DAB2,DAB2IP,FBXO32,GRAMD1A,HDAC5,HMGCS1,INSIG1,LBH,LITAF,LY96,MAPK1,MSN,NCOA1,NCOA4,NCOR2,NOS3,NR4A1,NRIP1,PLPP1,RHOA,RNF14,SIRPA,SPON2,TNFSF4,TRAF6,TRIP4,VIM,WBP2,WNT5B |
| GO_ALCOHOL_BIOSYNTHETIC_PROCESS | 1.0e-07 | 2.0e-06 | 1229 | 179 | 19 | ACAT2,CYB5R3,CYP51A1,DHCR24,EBP,ERG28,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,INSIG1,IP6K1,LSS,MSMO1,NSDHL,SC5D,SCD,SPTLC1 |
| GO_CILIUM_ORGANIZATION | 1.0e-07 | 1.9e-06 | 1229 | 381 | 29 | AKAP9,ATP6V1D,AVIL,BBS12,CEP126,CETN2,CFAP410,CSNK1D,CYLD,DCTN2,DYNC1H1,FAM161B,IFT27,KIF3C,KIFAP3,LCA5,MARK4,OFD1,RAB23,RP1L1,RSPH9,TAPT1,TBC1D7,TPGS1,TTBK2,TTLL3,UBE2B,WDPCP,WDR19 |
| GO_MAINTENANCE_OF_LOCATION | 1.0e-07 | 2.0e-06 | 1229 | 338 | 27 | AKAP9,ALKBH7,ANXA6,ARHGAP21,CAMK2D,CEMIP,DBN1,DYSF,FTH1,FTL,GAA,HK1,INSIG1,ITGAV,ITPR2,MCOLN1,MCOLN3,NRIP1,OS9,PINK1,PNPLA2,SKP1,SOAT1,STARD4,STAT5B,TAPT1,TMEM38A |
| GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | 1.0e-07 | 2.1e-06 | 1229 | 97 | 14 | CDC42,CRK,DMTN,EFNA1,ILK,ITGAV,KANK1,LAMC1,MDK,MEGF9,MYADM,NEDD9,PEAK1,WASHC2C |
| GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 1.0e-07 | 2.3e-06 | 1229 | 499 | 34 | AHNAK,ANXA6,ATP2B4,BEST1,CALCRL,CAMK2D,CEMIP,CTNNB1,CXCR4,DYSF,GNAI2,GRIN2D,INPP5K,ITGAV,ITPR2,LGALS3,MCOLN1,MCOLN3,MICU1,NIPA1,NOS3,PSEN1,RHOA,SARAF,SESTD1,SLC39A13,SLC41A2,TMEM165,TMEM38A,TRPC4AP,TRPM4,TRPM7,TRPV4,ZDHHC17 |
| GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS | 1.0e-07 | 2.4e-06 | 1229 | 320 | 26 | APOC1,CDIPT,CDS2,CPNE3,GPCPD1,HADHA,HADHB,INPP5K,IP6K1,LPIN1,LPIN2,MBOAT2,MTM1,MTMR3,PI4K2A,PIGG,PIP4K2C,PIP5K1C,PITPNM1,PLA2G15,PNPLA6,SERINC1,SERINC2,SERINC3,SERINC5,TMEM150A |
| GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 2.5e-06 | 1229 | 408 | 30 | ACVR1,CTNNA1,CTNNB1,CYLD,DAB2IP,DEDD2,EIF2AK3,ERP29,GNAI2,GRINA,GSK3B,HGF,HMOX1,ITGAV,LGALS3,MADD,MOAP1,NOS3,PINK1,PRKN,PSEN1,PTTG1IP,SERINC3,SKIL,TGFBR1,TMBIM1,TMEM102,VNN1,YWHAZ,ZNF205 |
| GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 2.0e-07 | 2.7e-06 | 1229 | 220 | 21 | AKAP9,CDK2AP2,CEP295NL,CHMP1B,CHMP2A,CTNNB1,CYLD,DYNC1H1,FGF13,GSK3B,IGBP1,MACF1,MAP1B,MAP2,MARK4,RHOA,RHOT1,SPEF1,TRIM54,TRPV4,TTBK2 |
| GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS | 2.0e-07 | 3.3e-06 | 1229 | 483 | 33 | ACSL1,ACTG1,ADAM17,ADCY2,ATP6AP1,BBS12,BTBD9,CLN8,CTNNB1,CXCR4,DECR1,DYNC1H1,ELOVL1,ERCC6,GNAS,INPP5K,IP6K1,LCA5,LPIN1,LRRK1,LTBP3,NOS3,NRDC,PLEKHM1,PRCP,RCN3,RP1L1,SCD,SCX,TP53INP2,TPP1,TRAF6,TRPV4 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 2.0e-07 | 3.2e-06 | 1229 | 860 | 48 | ARID5B,ATXN1,CIC,CTNNB1,CUX1,DAB2IP,DACT1,EAPP,EFNA1,FNIP1,FOXO4,FRK,GLIS2,HCFC2,HDAC5,HES6,IGBP1,JDP2,KDM5A,KLF11,KLF12,KLF2,LMCD1,MAFK,MOSPD1,MXD4,NCOR2,NOTCH2,NRIP1,PHF12,PHF21A,PKIG,PRKN,PSEN1,SIRT2,SKIL,SMAD7,SQSTM1,TCP10L,TRAF6,TRPV4,WDTC1,ZBTB4,ZFHX2,ZFHX3,ZHX2,ZNF205,ZNF281 |
| GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 2.0e-07 | 3.3e-06 | 1229 | 167 | 18 | CDH9,ITGB1,PALLD,PCDHB10,PCDHB13,PCDHB14,PCDHB15,PCDHB9,PCDHGA1,PCDHGA10,PCDHGA11,PCDHGA5,PCDHGA6,PCDHGA7,PCDHGA9,PCDHGB2,PCDHGB7,PCDHGC4 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 2.0e-07 | 3.4e-06 | 1229 | 243 | 22 | AKAP9,ARPC3,BAIAP2,C15orf62,CDC42EP2,CORO1B,CYFIP1,FNIP1,GMFG,GSK3B,MAP1B,MIEF2,MSN,MYO1C,PINK1,PPP2R5B,RHOA,RHOC,SH3GLB1,SNX9,WASHC2C,WASL |
| GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT | 2.0e-07 | 3.4e-06 | 1229 | 101 | 14 | EPS15,EXOC1,EXOC4,EXOC6B,MACF1,MON2,NSF,OPTN,RAB31,RP2,SCAMP2,SNAP23,SPTBN1,WIPI1 |
| GO_REGULATION_OF_DEVELOPMENTAL_GROWTH | 2.0e-07 | 3.5e-06 | 1229 | 348 | 27 | APP,CTDP1,CXCR4,CYFIP1,DBN1,FGF13,GDI1,GSK3B,ILK,INSR,LATS2,LRP1,MACF1,MAP1B,MAP2,MAPK1,MTM1,NRCAM,PLXNA3,PRKN,RTN4,SAV1,SEMA4B,SEMA6C,SGPL1,STAT5B,TGFBR1 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 2.0e-07 | 3.5e-06 | 1229 | 117 | 15 | DAB2,ITGB1,LGALS3,LRP1,NUMB,RHOG,RHOQ,SORBS1,SPTBN1,SQSTM1,STX3,STX7,STX8,TMBIM1,TMEM59 |
| GO_TRANSITION_METAL_ION_HOMEOSTASIS | 2.0e-07 | 3.4e-06 | 1229 | 133 | 16 | ACO1,APP,ATP13A2,ATP6AP1,BTBD9,CP,CYBRD1,FTH1,FTL,HMOX1,NCOA4,NDFIP1,PRKN,SKP1,SLC31A2,SLC39A13 |
| GO_AMEBOIDAL_TYPE_CELL_MIGRATION | 2.0e-07 | 3.6e-06 | 1229 | 462 | 32 | ACVR1,ADAM17,ARID5B,BCAS3,CAP1,CORO1B,DAB2IP,DCN,DMTN,EFNA1,FAP,GLUL,GRN,HDAC5,HMOX1,HRG,ILK,ITGB1,KANK1,MACF1,NOS3,NR4A1,PRCP,PRR5L,PTPRR,RHOA,RTN4,SEMA4B,SEMA6C,SGPL1,TGFBR1,WDPCP |
| GO_PEPTIDYL_TYROSINE_MODIFICATION | 2.0e-07 | 3.8e-06 | 1229 | 372 | 28 | ABI1,ACVR1,ADAM17,APP,CD81,CSPG4,DMTN,DSTYK,EFNA1,ERCC6,FRK,HGF,HIPK3,HRG,INSR,IQGAP1,JAK1,LRRK1,MAP2K2,MST1R,NEDD9,PEAK1,PPP2R5B,PSEN1,SH3BP5,SNX6,TMEM102,TNFRSF14 |
| GO_VIRAL_LIFE_CYCLE | 2.0e-07 | 3.8e-06 | 1229 | 328 | 26 | CD81,CDC42,CHMP1B,CHMP2A,CTSB,CXCR4,EFNB3,EPS15,FBXL2,FURIN,HYAL3,INPP5K,ITGAV,ITGB1,LRSAM1,MVB12B,PC,PRKN,RAB43,RAB7A,SCARB2,SHFL,TNFRSF14,TOP2B,TRIM21,TRIM35 |
| GO_TOR_SIGNALING | 2.0e-07 | 3.9e-06 | 1229 | 118 | 15 | CASTOR2,CASTOR3,FNIP1,LAMTOR3,MEAK7,MTM1,PINK1,PRR5L,RRAGC,SIK3,TBC1D7,TMEM127,TSC2,UBR2,WDR59 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 2.0e-07 | 4.2e-06 | 1229 | 88 | 13 | ATP13A2,CAMLG,DAB2IP,EFNA1,FURIN,GABARAPL2,MTM1,OPHN1,OS9,PSEN1,RGP1,SDCBP,UBXN1 |
| GO_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 2.0e-07 | 4.1e-06 | 1229 | 152 | 17 | EFNA1,EFNB3,FGF13,GDI1,GSK3B,KANK1,LRP1,MAP2,PLXNA3,PMP22,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,TRPV4,VIM |
| GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI | 2.0e-07 | 4.2e-06 | 1229 | 88 | 13 | CLTCL1,ERC1,HEATR5B,PRKN,RAB7A,RAB9A,RGP1,SNX6,SNX8,SPAG9,TBC1D17,TBC1D23,WASHC2C |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 2.0e-07 | 4.3e-06 | 1229 | 1116 | 57 | ABI1,ABR,ACTG1,APLF,ARPC3,BAIAP2,C1S,CD276,CD81,CDC42,CRK,CTSB,CYFIP1,CYLD,DAB2IP,DNASE2,DUSP3,FCER1G,FCGRT,GRAMD4,GRN,HK1,HMOX1,HRG,IGHV3-74,ITGB1,JAK1,LGALS3,LY96,MADCAM1,MAPK1,MAPKAPK2,MICA,MYO1C,NDFIP1,NLRP10,PJA2,PROS1,PSEN1,RAPGEF1,RFTN1,RTN4,SKP1,SLAMF6,SMAD7,SPON2,STAT5B,STING1,STX7,STXBP2,TANK,TNFRSF14,TNFSF4,TRAF6,TRPM4,WASL,WDFY1 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 3.0e-07 | 4.5e-06 | 1229 | 153 | 17 | ATG13,BCAS3,CD81,CDC42,CEMIP,CHP1,GSK3B,LEPROT,MAPK1,MIEF2,MYO1C,NPEPPS,PINK1,PRR5L,PSEN1,SH3GLB1,VPS11 |
| GO_RESPONSE_TO_TOXIC_SUBSTANCE | 3.0e-07 | 4.5e-06 | 1229 | 539 | 35 | AACS,ADH5,ASS1,CHRNB1,CRK,EEF2,ERCC6,FBLN5,HCN3,HGF,HMGCR,HMOX1,INMT,ITPR2,KDM5B,KLF2,MAP1B,MAP1LC3A,MAPK1,MT-ND5,MT-ND6,NOS3,NQO1,NUCB1,OSER1,PINK1,PRDX5,PRKN,PRXL2C,PSAP,RHOA,SIRPA,TP53INP1,TXNRD1,ZNF277 |
| GO_T_CELL_ACTIVATION | 3.0e-07 | 4.7e-06 | 1229 | 468 | 32 | ADAM17,CD151,CD276,CD81,CDC42,CTNNB1,CYLD,DUSP3,EFNB3,FCER1G,FZD8,GPNMB,LGALS3,LMBR1L,MAP3K8,MDK,MICA,MSN,NDFIP1,PSEN1,RHOA,SIRPA,SIRPB1,SLAMF6,SMAD7,STAT5B,TNFRSF14,TNFSF4,TRAF6,TWSG1,VNN1,ZMIZ1 |
| GO_RAB_PROTEIN_SIGNAL_TRANSDUCTION | 3.0e-07 | 4.9e-06 | 1229 | 75 | 12 | GDI1,IFT27,MADD,RAB23,RAB31,RAB32,RAB43,RAB4B,RAB5B,RAB7A,RAB8B,RAB9A |
| GO_VESICLE_LOCALIZATION | 3.0e-07 | 5.2e-06 | 1229 | 210 | 20 | CLN3,CSNK1D,CTNNB1,DCTN2,DYNC1H1,EXOC4,GOLGA2,KIFAP3,MAP2,MYO1C,NSF,PINK1,PRKN,PSEN1,SNAP23,TBC1D23,TPGS1,TRAPPC6A,WASL,WIPI1 |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 3.0e-07 | 5.6e-06 | 1229 | 960 | 51 | ADAM17,AKR1C3,ARNT,ARNT2,CACUL1,CALCRL,CAPN1,CAPNS1,CD276,CD81,CDC42,CTNNB1,DYSF,EAPP,EGR4,ESM1,FOSL2,GLUL,GNAI2,GRN,HMGCR,HMOX1,ILK,INSR,ITGAV,ITGB1,KDM5B,LAMC1,LBH,LTBP3,MAPK1,MDK,MST1,MST1R,NOTCH2,NR4A1,OSMR,RHOG,ROGDI,RTN4,S100A13,SCX,SDCBP,STAT5B,STX3,TGFBR1,TNFSF4,TRAF6,TRPM4,TSPAN31,ZMIZ1 |
| GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 3.0e-07 | 5.6e-06 | 1229 | 192 | 19 | ACVR1,ADAM17,ADAMTSL2,CD109,DAB2,FAM89B,FURIN,GLG1,LTBP3,RHOA,SDCBP,SKIL,SMAD7,SMAD9,SNX6,TGFBR1,TWSG1,USP9Y,VASN |
| GO_EPITHELIAL_CELL_DIFFERENTIATION | 4.0e-07 | 5.9e-06 | 1229 | 774 | 44 | ACVR1,AKR1C3,ANXA4,CAPN1,CAPNS1,CD109,CDC42,CLIC4,CTNNB1,CTSB,CXCR4,DAB2,DSP,FN3K,FOSL2,FURIN,GSK3B,IQGAP1,KDM5B,KIAA1109,KLF2,LBH,LGALS3,MCOLN3,MSN,MYADM,NOTCH2,OPHN1,PALLD,PAX8,PSAP,RAPGEF1,RHOA,SAV1,SCX,SHARPIN,SKIL,STAT5B,TAGLN,TOLLIP,TPP1,VIM,WDPCP,WNT5B |
| GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 4.0e-07 | 5.9e-06 | 1229 | 122 | 15 | CD81,CEMIP,CHP1,ITGB1,LGALS3,LRP1,MIEF2,MYO1C,PRKN,RHOG,SORBS1,SPTBN1,SQSTM1,STX3,YWHAZ |
| GO_CELLULAR_IRON_ION_HOMEOSTASIS | 4.0e-07 | 6.1e-06 | 1229 | 63 | 11 | ACO1,ATP13A2,ATP6AP1,CP,CYBRD1,FTH1,FTL,HMOX1,NCOA4,NDFIP1,SKP1 |
| GO_HORMONE_MEDIATED_SIGNALING_PATHWAY | 4.0e-07 | 6.1e-06 | 1229 | 232 | 21 | ABHD2,ACSL1,AKAP13,CALCOCO1,CREBRF,CTNNB1,DAB2,LATS2,LBH,NCOA1,NCOA4,NCOR2,NR4A1,NRIP1,PLPP1,PRCP,RHOA,RNF14,TRIP4,UCN2,WBP2 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 4.0e-07 | 6.1e-06 | 1229 | 232 | 21 | ARNT,CAMLG,CHP1,CTNNB1,DNAJB2,DYSF,GOLGA2,NDFIP1,PINK1,PRKN,PSEN1,PTTG1IP,SMAD7,SQSTM1,TANK,TBC1D7,TGFBR1,TOLLIP,TRAF6,TRIM21,UBXN1 |
| GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 4.0e-07 | 6.1e-06 | 1229 | 232 | 21 | AKR1C3,APOD,CRK,EEF2,ERCC6,FBLN5,HGF,HMOX1,KLF2,MAP1LC3A,MAPK1,MT-ND5,MT-ND6,NOS3,NQO1,OSER1,PINK1,PRDX5,PSAP,SIRPA,ZNF277 |
| GO_CANONICAL_WNT_SIGNALING_PATHWAY | 4.0e-07 | 6.2e-06 | 1229 | 337 | 26 | CSNK1D,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,FRAT1,FZD8,GSK3B,IGFBP6,ILK,KANK1,LATS2,LMBR1L,LRRK1,MDK,NID1,PPM1N,PRKN,PSEN1,RAPGEF1,RNF146,TMEM88,TRPM4,UBE2B,WNT5B |
| GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 4.0e-07 | 6.2e-06 | 1229 | 273 | 23 | AKAP13,CTNNB1,DAB2IP,ERC1,HMOX1,LITAF,LY96,MIB2,NDFIP1,OPTN,PINK1,PPM1N,PRKN,RHOA,RHOC,S100A13,SHARPIN,SIRPA,SQSTM1,TANK,TMED4,TRAF6,ZDHHC17 |
| GO_NEGATIVE_REGULATION_OF_CELL_ADHESION | 4.0e-07 | 6.2e-06 | 1229 | 294 | 24 | APOD,ARHGDIG,ASS1,BCAS3,CD164,CORO2B,DMTN,DUSP3,GPNMB,HRG,KANK1,LGALS3,LRP1,MDK,MYADM,NDFIP1,PLXNA3,RHOA,SMAD7,SWAP70,TNFRSF14,TNFSF4,TRPV4,TWSG1 |
| GO_POSITIVE_REGULATION_OF_SECRETION | 4.0e-07 | 7.3e-06 | 1229 | 431 | 30 | AACS,ATP13A2,ATP6AP1,CHMP2A,EXOC1,FCER1G,FRMD4A,FRMD8,GALR1,GLUL,GNAI2,HK1,HYAL3,IL17RA,LRP1,MDK,MPC2,NLRP10,PINK1,PLA2R1,RAB7A,RAB8B,RAB9A,SDCBP,SPTBN1,STXBP5,TNFRSF14,TNFSF4,TRPM4,TRPV4 |
| GO_REGULATION_OF_PEPTIDASE_ACTIVITY | 4.0e-07 | 7.5e-06 | 1229 | 455 | 31 | APLP2,APP,ATP13A2,CD109,CST3,CSTB,CTSD,DHCR24,EFNA1,EIF2AK3,FNIP1,FURIN,GRAMD4,GRN,HGF,HRG,IGBP1,LRP1,MICAL1,NRDC,PINK1,PRDX5,PROS1,RCN3,RHOA,RPS27L,SERPINB1,SERPINB6,TANK,TIMP2,UBXN1 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 5.0e-07 | 7.7e-06 | 1229 | 627 | 38 | ACAT1,ACOT8,ACSL1,ACSS2,ADCY2,ALDH6A1,APP,ARNT,CDA,CDIPT,CDS2,ELOVL1,HK1,HMGCR,HMGCS1,INSR,MAPK1,MPC2,MT-ATP6,MT-ATP8,NAGK,NOS3,NT5C2,PGM1,PGM2L1,PINK1,PMM1,PRXL2C,PSEN1,RAB23,RHOA,RHOQ,SCD,SLC2A6,SMPDL3A,SULT1C2,TXNRD1,UPB1 |
| GO_ACTIVATION_OF_MAPKK_ACTIVITY | 5.0e-07 | 7.9e-06 | 1229 | 52 | 10 | CRK,ERCC6,LAMTOR3,MAP3K10,MAP3K8,MAPK1,PSEN1,RAPGEF1,TAOK3,TGFBR1 |
| GO_CELLULAR_RESPONSE_TO_CAMP | 5.0e-07 | 7.9e-06 | 1229 | 52 | 10 | AKAP9,APP,AQP9,ASS1,DMTN,INPP5K,ITPR2,KCNE1,RAPGEF1,SLC26A6 |
| GO_REGULATION_OF_EXOCYTOSIS | 5.0e-07 | 7.9e-06 | 1229 | 216 | 20 | ABR,APBA2,ATP13A2,ATP6AP1,CHMP2A,FCER1G,GNAI2,GSK3B,HMOX1,HYAL3,MICAL1,NSF,PRKN,RAB7A,RAB8B,RAB9A,SDCBP,STXBP2,STXBP5,SYT15 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 5.0e-07 | 8.3e-06 | 1229 | 1198 | 59 | ACVR1,APP,ARMCX3,ARNT,ARNT2,ATP1B4,AUTS2,BCAS3,CALCOCO1,CAMTA2,CD81,CREBRF,CTCFL,CTNNB1,DAB2IP,DCAF6,DCN,EAPP,EGR4,FOSL2,FOXO4,GALR1,GLIS2,GLMP,HDAC5,HGF,HIF3A,INSIG1,KLF12,KLF13,KLF2,KLF6,KMT2C,LITAF,LPIN1,LPIN2,MOSPD1,NCOA1,NFAT5,NR4A1,NRIP1,PAX8,PPP2R5B,PRKN,RHOQ,SCX,SIRT2,SMAD7,SMAD9,SQSTM1,STAT2,STAT5B,STING1,TEAD1,TRAF6,WASL,WBP2,ZFHX3,ZMIZ1 |
| GO_REGULATION_OF_CELL_CELL_ADHESION | 5.0e-07 | 8.5e-06 | 1229 | 411 | 29 | ASS1,CD276,CD81,CDC42,CYLD,DMTN,DUSP3,EFNB3,GPNMB,KIFAP3,LGALS3,MAP3K8,MDK,MYADM,NDFIP1,NFAT5,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,SWAP70,TNFRSF14,TNFSF4,TRAF6,TRPV4,TWSG1,VNN1,ZMIZ1 |
| GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS | 6.0e-07 | 9.1e-06 | 1229 | 110 | 14 | ACO1,APP,ATP13A2,ATP6AP1,CP,CYBRD1,FTH1,FTL,HMOX1,NCOA4,NDFIP1,SKP1,SLC31A2,SLC39A13 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 6.0e-07 | 9.4e-06 | 1229 | 323 | 25 | CEMIP,CHM,CHP1,DMTN,EXOC4,GDI1,INPP5K,KCNE1,MACF1,MIEF2,MOAP1,MYO1C,NSF,OPTN,RAB31,RAB8B,RFTN1,SDCBP,SPTBN1,SRP14,STX3,YWHAZ,ZDHHC1,ZDHHC2,ZDHHC7 |
| GO_LYMPHOCYTE_ACTIVATION | 6.0e-07 | 9.4e-06 | 1229 | 736 | 42 | ADAM17,APLF,CD151,CD276,CD81,CDC42,CTNNB1,CYLD,DUSP3,EFNB3,FCER1G,FNIP1,FZD8,GPNMB,HDAC5,IGBP1,IGHV3-74,ITGB1,KLF6,LGALS3,LMBR1L,LRRC8A,MAP3K8,MDK,MICA,MSN,NDFIP1,NOTCH2,PSEN1,RHOA,SIRPA,SIRPB1,SLAMF6,SMAD7,STAT5B,SWAP70,TNFRSF14,TNFSF4,TRAF6,TWSG1,VNN1,ZMIZ1 |
| GO_BONE_DEVELOPMENT | 6.0e-07 | 9.6e-06 | 1229 | 219 | 20 | ABI1,AKAP13,ANXA6,ATP6AP1,COL13A1,COL6A1,COL6A2,GLG1,GNAS,INSIG1,LRRK1,LTBP3,MATN3,NOTCH2,RAB23,RHOA,SCX,TAPT1,THBS3,TRPV4 |
| GO_SKELETAL_SYSTEM_MORPHOGENESIS | 6.0e-07 | 9.6e-06 | 1229 | 239 | 21 | ACAN,ALX3,ANXA6,ARID5B,COL13A1,COL6A1,COL6A2,CTNNB1,GLG1,GNAS,INSIG1,LTBP3,MATN3,PSEN1,RAB23,SCX,SGPL1,TGFBR1,THBS3,TRPV4,WDR19 |
| GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 6.0e-07 | 9.6e-06 | 1229 | 763 | 43 | ABI1,AMBRA1,APOD,APP,CD109,CD164,CTNNA1,CTNNB1,DAB2IP,DHCR24,DNAJB2,FAP,FOXO4,FRK,FTH1,GPNMB,HMOX1,HRG,IFIT3,IGFBP6,ILK,ING4,ITGA1,KIFAP3,KLF11,KLF13,MXD4,NDFIP1,NOS3,PLPP1,PMP22,RAPGEF1,S100A11,SAV1,SIRT2,TGFBR1,TIMP2,TINF2,TMEM127,TNFRSF14,TP53INP1,TSC2,TWSG1 |
| GO_MITOPHAGY | 7.0e-07 | 1.1e-05 | 1229 | 22 | 7 | AMBRA1,ATG13,OPTN,PINK1,PRKN,SQSTM1,TSC2 |
| GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 7.0e-07 | 1.1e-05 | 1229 | 261 | 22 | CDIPT,CDS2,CPNE3,FDPS,HMGCS1,IDH1,IDI1,INPP5K,LPIN1,LPIN2,MBOAT2,MTM1,MTMR3,PI4K2A,PIGG,PIP4K2C,PIP5K1C,PITPNM1,SAMD8,SERINC1,SERINC5,SPTLC1 |
| GO_IRON_ION_HOMEOSTASIS | 7.0e-07 | 1.1e-05 | 1229 | 81 | 12 | ACO1,ATP13A2,ATP6AP1,BTBD9,CP,CYBRD1,FTH1,FTL,HMOX1,NCOA4,NDFIP1,SKP1 |
| GO_LAMELLIPODIUM_ORGANIZATION | 7.0e-07 | 1.1e-05 | 1229 | 81 | 12 | ABI1,ARHGEF6,AUTS2,CAPZB,CDC42,CORO1B,CYFIP1,DMTN,HRG,ITGB1,KANK1,PLEKHO1 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 7.0e-07 | 1.1e-05 | 1229 | 440 | 30 | ACAT1,ACAT2,ACOT8,ACOX1,ADH5,AKR1C3,ALDH6A1,ATP2B4,CDA,CEMIP,CHP1,DECR1,EHHADH,GK,GLUL,HADHA,HADHB,HK1,HYAL3,INPP5K,LPIN1,LPIN2,NAGK,NOS3,PGM1,PGM2L1,PHYH,PLA2G15,RBKS,UPB1 |
| GO_VESICLE_MEDIATED_TRANSPORT_BETWEEN_ENDOSOMAL_COMPARTMENTS | 7.0e-07 | 1.1e-05 | 1229 | 42 | 9 | DAB2,DENND10,MAP2K2,MAPK1,MSN,RAB7A,RILP,STX8,VPS11 |
| GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 7.0e-07 | 1.1e-05 | 1229 | 96 | 13 | DMTN,EFNA1,EFNB3,FGF13,GDI1,KANK1,MAP2,PLXNA3,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C |
| GO_NEGATIVE_REGULATION_OF_LOCOMOTION | 8.0e-07 | 1.2e-05 | 1229 | 396 | 28 | ABHD2,ABR,APOD,CLIC4,CORO1B,CRK,CTNNA1,DAB2IP,DCN,DUSP3,HDAC5,HMOX1,HRG,ILK,KANK1,LIMCH1,LRP1,PLXNA3,PTPRR,RHOA,RRAS,SEMA4B,SEMA6C,SMAD7,TP53INP1,TRIM21,TRIM35,WASL |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 8.0e-07 | 1.3e-05 | 1229 | 468 | 31 | ADAM17,APP,ARNT,ATP6AP2,CD276,CD81,CTNNB1,EIF2AK3,FCER1G,FRMD8,FURIN,HGF,HK1,HMOX1,IL17RA,LRP1,LY96,MAPKAPK2,MDK,NLRP10,PSEN1,SLAMF6,SPON2,SPTBN1,STAT5B,STING1,TBC1D23,TNFRSF14,TNFSF4,TRAF6,TRPV4 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | 9.0e-07 | 1.4e-05 | 1229 | 131 | 15 | AKAP9,ARPC3,BAIAP2,C15orf62,CDC42EP2,CORO1B,CYFIP1,GMFG,MAP1B,MYO1C,PINK1,RHOA,SNX9,WASHC2C,WASL |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 9.0e-07 | 1.5e-05 | 1229 | 594 | 36 | ACAT1,ACSL1,ACSS2,ADCY2,CDIPT,CDS2,CPNE3,ELOVL1,FDPS,GK,HMGCS1,IDH1,IDI1,INPP5K,IP6K1,LPIN1,LPIN2,MAPK1,MBOAT2,MPC2,MT-ATP6,MT-ATP8,MTM1,MTMR3,NOS3,PI4K2A,PIGG,PINK1,PIP4K2C,PIP5K1C,PITPNM1,SAMD8,SCD,SERINC1,SERINC5,SPTLC1 |
| GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 9.0e-07 | 1.5e-05 | 1229 | 288 | 23 | CERT1,CREBRF,CTDSP2,CUL7,DAB2IP,DNAJB2,DNAJC3,EEF2,EIF2AK3,ERP29,GRINA,GSK3B,OS9,PPP2R5B,PRKN,RCN3,RNF103,SERINC3,TPP1,UBE4B,UBXN1,UBXN6,WIPI1 |
| GO_LEUKOCYTE_DIFFERENTIATION | 1.0e-06 | 1.5e-05 | 1229 | 520 | 33 | ADAM17,APP,ATP6AP1,CD109,CD81,CDC42,CTNNB1,CYLD,FCER1G,FNIP1,FZD8,GNAS,HDAC5,ITGB1,KLF6,LMBR1L,LRRC8A,LRRK1,MDK,NDFIP1,NOTCH2,OSTM1,PSEN1,RHOA,RRAS,SLAMF6,SMAD7,STAT5B,TCTA,TNFSF4,TRAF6,VNN1,ZMIZ1 |
| GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 1.0e-06 | 1.5e-05 | 1229 | 310 | 24 | APP,CTNNA1,CTNNB1,EFNA1,EFNB3,EIF2AK3,FGF13,GDI1,GPR161,GSK3B,KANK1,LRP1,MAP2,PLXNA3,PMP22,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,SIRT2,TRPV4,VIM,ZHX2 |
| GO_MEMBRANE_LIPID_METABOLIC_PROCESS | 1.0e-06 | 1.6e-05 | 1229 | 207 | 19 | CERT1,CLN8,CTSA,ELOVL1,ESYT1,ESYT2,NEU1,PIGG,PLA2G15,PLPP1,PSAP,SAMD8,SERINC1,SERINC2,SERINC3,SERINC5,SGPL1,SMPD1,SPTLC1 |
| GO_ACTIVATION_OF_MAPK_ACTIVITY | 1.2e-06 | 1.9e-05 | 1229 | 152 | 16 | CD81,CSPG4,CXCR4,DAB2IP,ERCC6,ERP29,HGF,INSR,ITGA1,MADD,MAP2K2,MAP3K10,MAPK1,MAPKAPK2,SPAG9,TRAF6 |
| GO_CARBOHYDRATE_DERIVATIVE_CATABOLIC_PROCESS | 1.2e-06 | 1.8e-05 | 1229 | 189 | 18 | ACAN,ACAT1,CDA,CEMIP,CHP1,CSPG4,CST3,CTBS,DCN,GALNS,GNS,HYAL3,MANBA,NAGK,NEU1,PSAP,SDC2,UPB1 |
| GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 1.2e-06 | 1.9e-05 | 1229 | 117 | 14 | ATG13,DCN,GSK3B,LEPROT,MIEF2,MOAP1,NPEPPS,OPTN,PINK1,PRKN,SH3GLB1,VPS11,YWHAZ,ZNF205 |
| GO_REGULATION_OF_DENDRITE_DEVELOPMENT | 1.2e-06 | 1.9e-05 | 1229 | 152 | 16 | BAIAP2,CRK,CUL7,CUX1,CYFIP1,DAB2IP,DBN1,EFNA1,GSK3B,ILK,IQGAP1,LZTS3,PSEN1,PTPRD,RHOA,SDC2 |
| GO_ANION_TRANSMEMBRANE_TRANSPORT | 1.3e-06 | 2.1e-05 | 1229 | 294 | 23 | ANO10,AQP9,BEST1,CLCN3,CLCN6,CLCN7,CLIC4,CLN8,LRRC8A,MPC2,PSEN1,SLC12A4,SLC12A6,SLC13A1,SLC15A4,SLC26A11,SLC26A4,SLC26A6,SLC37A1,SLC38A2,SLC38A7,SLC43A2,SLC4A3 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | 1.3e-06 | 1.9e-05 | 1229 | 190 | 18 | CAPZB,CTSD,CTSF,DCTN2,DYNC1H1,FCER1G,FCGRT,ITGAV,KIF3C,KIFAP3,MICA,NCF2,OSBPL1A,RAB7A,RILP,SNAP23,TAPBPL,TRAF6 |
| GO_DEPHOSPHORYLATION | 1.3e-06 | 2.1e-05 | 1229 | 479 | 31 | CHP1,CTDP1,CTDSP2,DUSP3,GNAI2,GSK3B,IGBP1,INPP5K,IQGAP1,ITGA1,LGALS3,LPIN1,LPIN2,MTM1,MTMR3,NT5C2,NUAK1,PINK1,PLPP1,PPEF2,PPM1N,PPP2R5B,PTPN21,PTPRD,PTPRH,PTPRR,SHOC2,SMG6,SMPD1,SWAP70,ZFYVE1 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 1.4e-06 | 2.2e-05 | 1229 | 362 | 26 | APP,CSNK1D,CTSD,DAB2,DAB2IP,DNAJB2,EFNA1,EIF2AK3,FURIN,GRAMD4,GRN,GSK3B,NRDC,PINK1,PRKN,PSEN1,RCN3,RHOA,RNF14,RPS27L,SIRT2,SMAD7,SNX33,SNX9,TANK,ZER1 |
| GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 1.5e-06 | 2.3e-05 | 1229 | 433 | 29 | ACTG1,ATP6AP1,BBS12,CALB1,CLN8,CTNNB1,DNAJB2,ERCC6,GAA,GNAS,LAMP2,LCA5,LRRK1,LTBP3,MAPK1,MTM1,NOS3,PLEKHM1,POLD4,PRKN,RCN3,RP1L1,SCX,SMARCAL1,SMG6,TINF2,TP53INP2,TPP1,TRAF6 |
| GO_REGULATION_OF_CELL_MATRIX_ADHESION | 1.5e-06 | 2.2e-05 | 1229 | 119 | 14 | APOD,BCAS3,DMTN,DUSP3,GSK3B,HRG,ILK,IQGAP1,LIMCH1,LRP1,MACF1,PEAK1,RHOA,WDPCP |
| GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | 1.7e-06 | 2.6e-05 | 1229 | 104 | 13 | CD63,CDC42,CTNNA1,DMTN,DST,FCER1G,ILK,ITGA1,ITGA7,ITGAV,ITGB1,MADCAM1,NEDD9 |
| GO_MESENCHYME_DEVELOPMENT | 1.7e-06 | 2.5e-05 | 1229 | 276 | 22 | ACVR1,CRELD1,CTNNB1,CUL7,DAB2,DAB2IP,EFNA1,EXOC4,GSK3B,HGF,MAPK1,MDK,NOS3,RTN4,SCX,SDCBP,SEMA4B,SEMA6C,SMAD7,TAPT1,TGFBR1,VASN |
| GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY | 1.9e-06 | 2.9e-05 | 1229 | 139 | 15 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,BAIAP2,FOXO4,GNAI2,GSK3B,INPP5K,INSR,KANK1,RHOQ,SORBS1,TSC2 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | 1.9e-06 | 2.9e-05 | 1229 | 74 | 11 | DYNC1H1,LRSAM1,MARK4,MSN,MYLK3,PIP4K2C,RHOA,SDCBP,SH3GLB1,TAPT1,ULK1 |
| GO_SYNAPSE_ORGANIZATION | 1.9e-06 | 2.8e-05 | 1229 | 414 | 28 | ACTG1,APP,BAIAP2,CDC42,CDH9,CHRNB1,CTNNB1,CYFIP1,DAB2IP,DBN1,EFNA1,INSR,LZTS3,MAP1B,NRCAM,NRDC,OPHN1,PCDHB10,PCDHB13,PCDHB14,PCDHB9,PCDHGC4,PSEN1,PTPRD,RHOA,SPARCL1,WASL,YWHAZ |
| GO_REGULATION_OF_CHEMOTAXIS | 2.0e-06 | 3.0e-05 | 1229 | 216 | 19 | ADAM17,CORO1B,CXCR4,DUSP3,DYSF,HRG,MDK,MOSPD2,MST1,MTUS1,PLXNA3,SEMA4B,SEMA6C,STX3,SWAP70,TMEM102,TRPV4,ZSWIM4,ZSWIM8 |
| GO_PEPTIDE_SECRETION | 2.1e-06 | 3.1e-05 | 1229 | 641 | 37 | AACS,ANXA4,ATP13A2,CHI3L1,COPG1,CYP51A1,DMTN,DYSF,ERP29,EXOC1,FRMD4A,FRMD8,GLUL,HK1,HMGCR,IL17RA,ITGAV,ITPR2,LRP1,MDK,MPC2,NLRP10,NOTCH2,PAX8,PRKN,RAB11FIP5,RAB8B,RCN3,RHBDF1,S100A13,SERPINB1,SPTBN1,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4 |
| GO_RECEPTOR_RECYCLING | 2.1e-06 | 3.2e-05 | 1229 | 36 | 8 | ARAP1,CAMLG,EPS15,NSF,OPTN,PCSK9,PSEN1,REP15 |
| GO_REGULATION_OF_AUTOPHAGOSOME_ASSEMBLY | 2.1e-06 | 3.2e-05 | 1229 | 36 | 8 | LRSAM1,MTM1,MTMR3,PINK1,PIP4K2C,SH3GLB1,TBC1D12,ULK1 |
| GO_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE | 2.1e-06 | 3.2e-05 | 1229 | 36 | 8 | CEMIP,CHP1,DMTN,GDI1,INPP5K,KCNE1,MIEF2,MYO1C |
| GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION | 2.2e-06 | 3.3e-05 | 1229 | 159 | 16 | ARAP1,BAIAP2,CDC42,CORO1B,CORO2B,DMTN,INPP5K,LIMCH1,MICAL1,NEDD9,PRKN,RHOA,RHOC,SORBS1,SWAP70,TGFBR1 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 2.2e-06 | 3.3e-05 | 1229 | 643 | 37 | ADAM17,CD81,CDK19,CTSB,CXCR4,CYLD,DAB2IP,DYSF,FCER1G,GRAMD4,GRN,HRG,IL17RA,LRP1,LRSAM1,LY96,MAPKAPK2,MDK,MOSPD2,NLRP10,OPTN,OSMR,PJA2,RFTN1,RTN4,SKP1,SLAMF6,STAT5B,STING1,STX3,SWAP70,TANK,TMEM102,TNFSF4,TRAF6,TRPV4,WDFY1 |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 2.2e-06 | 3.3e-05 | 1229 | 348 | 25 | ACVR1,ADAM17,ADAMTSL2,CD109,DAB2,FAM89B,FURIN,GLG1,ILK,LTBP3,NOTCH2,RHOA,SCX,SDCBP,SKIL,SMAD7,SMAD9,SNX6,SPTBN1,TGFBR1,TWSG1,USP9Y,VASN,VIM,ZFYVE16 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 2.3e-06 | 3.4e-05 | 1229 | 804 | 43 | ABR,APOD,CALCRL,CD81,CDK19,CRK,CTSB,CYLD,DAB2IP,DNASE1,ERCC6,FCER1G,FNDC4,GRAMD4,GRN,HGF,IL17RA,JAK1,LRSAM1,LY96,MAPKAPK2,MDK,MICA,NDFIP1,NLRP10,OPTN,OSMR,PJA2,RFTN1,RTN4,SHARPIN,SIRPA,SIRT2,SKP1,SLAMF6,STAT5B,STING1,TANK,TBC1D23,TNFSF4,TRAF6,TRPV4,WDFY1 |
| GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 2.3e-06 | 3.4e-05 | 1229 | 198 | 18 | ABR,APLF,CD81,CRK,DNASE1,FCER1G,FCGRT,HMOX1,MICA,NDFIP1,SLAMF6,SMAD7,STAT5B,STX7,STXBP2,TNFSF4,TRAF6,TRPM4 |
| GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | 2.3e-06 | 3.3e-05 | 1229 | 48 | 9 | APP,CEMIP,CHI3L1,DMTN,INPP5K,MAPK1,PPEF2,SIRT2,SMAD7 |
| GO_RESPONSE_TO_INTERFERON_GAMMA | 2.3e-06 | 3.4e-05 | 1229 | 198 | 18 | ACTG1,ASS1,CALCOCO2,CAMK2D,CDC42,CDC42EP2,GBP2,IRF9,JAK1,MYO1C,RAB43,SHFL,SIRPA,SLC26A6,STX8,STXBP2,TRIM21,VIM |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 2.3e-06 | 3.5e-05 | 1229 | 372 | 26 | ACAN,ACAT1,ACOT8,ACSL1,ACSS2,AHCYL2,B3GNT2,CHPF,CSPG4,CTNS,DCN,ELOVL1,ETHE1,GALNS,GNS,HMGCS1,IDH1,MICAL1,MPC2,OPLAH,PAX8,PC,SCD,STAT5B,SULT1C2,UST |
| GO_MALE_SEX_DIFFERENTIATION | 2.4e-06 | 3.5e-05 | 1229 | 160 | 16 | AGO4,AKR1C3,ARID5B,CTNNA1,CTNNB1,DHCR24,HMGCS1,INSR,KDM5A,NCOA1,NCOA4,REC8,SCX,SGPL1,STAT5B,TGFBR1 |
| GO_MICROTUBULE_BASED_MOVEMENT | 2.5e-06 | 3.7e-05 | 1229 | 283 | 22 | APP,ARHGAP21,ARL8A,ARL8B,BBS12,CDC42,CLN3,COPG1,DST,DYNC1H1,IFT27,IGBP1,KIAA0556,KIF3C,KIFAP3,LCA5,MAP1B,MAP2,OFD1,RHOT1,RSPH9,WDR19 |
| GO_LYTIC_VACUOLE_ORGANIZATION | 2.6e-06 | 3.8e-05 | 1229 | 62 | 10 | CLN3,CLN8,GAA,GRN,HPS1,LYST,RAB7A,SCARB2,TMEM165,TPP1 |
| GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 2.6e-06 | 3.9e-05 | 1229 | 200 | 18 | AKR1C3,APOC1,CREBL2,CYP51A1,FDFT1,FDPS,HMGCR,HMGCS1,IDH1,IDI1,INSIG1,LSS,SAMD8,SC5D,SCD,SORBS1,STARD4,WDTC1 |
| GO_TISSUE_REMODELING | 2.6e-06 | 3.8e-05 | 1229 | 180 | 17 | ABR,ATP6AP1,CAPN1,CSPG4,CST3,CTNNB1,GPNMB,HRG,LRRK1,LTBP3,MDK,NOS3,NOTCH2,PLEKHM1,TMBIM1,TPP1,TRAF6 |
| GO_CELL_CHEMOTAXIS | 2.7e-06 | 3.9e-05 | 1229 | 306 | 23 | ADAM17,CORO1B,CRK,CXCR4,DYSF,FCER1G,HGF,HRG,IL17RA,ITGA1,LGALS3,LYST,MDK,MOSPD2,MST1,MTUS1,NR4A1,PIP5K1C,RHOG,SWAP70,TMEM102,TRPM4,TRPV4 |
| GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 2.7e-06 | 3.9e-05 | 1229 | 125 | 14 | CAMLG,CSNK1D,DAB2,DNAJB2,GSK3B,MTM1,PRKN,PSEN1,RNF14,SDCBP,SIRT2,SMAD7,UBXN1,ZER1 |
| GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY | 2.8e-06 | 4.0e-05 | 1229 | 181 | 17 | ABHD2,AKAP13,CALCOCO1,CREBRF,CTNNB1,DAB2,LBH,NCOA1,NCOA4,NCOR2,NR4A1,NRIP1,PLPP1,RHOA,RNF14,TRIP4,WBP2 |
| GO_IRON_ION_TRANSPORT | 2.9e-06 | 4.2e-05 | 1229 | 77 | 11 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CP,FTH1,FTL,HRG,MCOLN1,REP15 |
| GO_NEURON_DEATH | 2.9e-06 | 4.2e-05 | 1229 | 353 | 25 | AMBRA1,APP,ATP13A2,CDC42,CHP1,CLN3,CTNNB1,DHCR24,GPNMB,GRN,GSK3B,HMOX1,ILK,ITGA1,LRP1,MDK,MEAK7,NQO1,PCSK9,PINK1,PRKN,PSEN1,RHOA,RRAS2,SNX6 |
| GO_REGULATION_OF_STEROID_METABOLIC_PROCESS | 2.9e-06 | 4.2e-05 | 1229 | 126 | 14 | AKR1C3,APOC1,CYP51A1,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,INSIG1,LSS,SC5D,SCD,STARD4,STAT5B |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 3.0e-06 | 4.3e-05 | 1229 | 1036 | 51 | AGO4,AKAP9,ARPC3,ATPAF2,AVIL,BAIAP2,BBS12,BRD2,C15orf62,CAPG,CAPZB,CDC42EP2,CETN2,CHMP2A,CORO1B,CSNK1D,CYFIP1,DBN1,DMTN,EPS15,FCHO2,FGF13,GMFG,GOLGA2,KANK1,MAP1B,MAP2,MAP7D3,MT-ND2,MT-ND5,MT-ND6,MYADM,MYO1C,PDE4DIP,PINK1,PRKN,RHOA,RPS10P5,RPS27L,RTN4,SIRT2,SNAP23,SNX9,SPTBN1,SRPK3,TAPBPL,TRPV4,VPS11,WASHC2C,WASHC3,WASL |
| GO_DENDRITE_MORPHOGENESIS | 3.0e-06 | 4.2e-05 | 1229 | 144 | 15 | ABI1,BAIAP2,CDC42,CUL7,CUX1,DBN1,EFNA1,GSK3B,ILK,ITGB1,LZTS3,MAP2,PTPRD,SDC2,WASL |
| GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 3.0e-06 | 4.3e-05 | 1229 | 286 | 22 | CHP1,DAB2IP,DNAJC3,DUSP3,GMFG,GSK3B,HIPK3,HMGCR,ILK,INPP5K,LATS2,PIK3IP1,PKIG,PRKN,PSEN1,RUBCN,SH3BP5,SMAD7,SMPD1,SNX6,TAOK3,TSC2 |
| GO_PROTEIN_LOCALIZATION_TO_VACUOLE | 3.0e-06 | 4.4e-05 | 1229 | 63 | 10 | CD81,LAMP2,MEAK7,NCOA4,RAB7A,RTN4,SCARB2,SH3GLB1,TRAPPC8,ZFYVE16 |
| GO_REGULATION_OF_EARLY_ENDOSOME_TO_LATE_ENDOSOME_TRANSPORT | 3.1e-06 | 4.5e-05 | 1229 | 18 | 6 | DAB2,DENND10,MAP2K2,MAPK1,MSN,VPS11 |
| GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | 3.2e-06 | 4.5e-05 | 1229 | 223 | 19 | AGO4,AKR1C3,ARID5B,CTNNA1,HMGCS1,HYAL3,IDH1,INSR,KDM5A,NCOA1,NCOA4,NOS3,NRIP1,REC8,SCX,SGPL1,STAT5B,TGFBR1,WDR19 |
| GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 3.2e-06 | 4.5e-05 | 1229 | 223 | 19 | APP,EFNA1,EFNB3,FGF13,GDI1,GSK3B,KANK1,LRP1,MAP2,PLXNA3,PMP22,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,TRPV4,VIM,ZHX2 |
| GO_REGULATION_OF_CHOLESTEROL_BIOSYNTHETIC_PROCESS | 3.2e-06 | 4.6e-05 | 1229 | 50 | 9 | CYP51A1,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,LSS,SC5D,SCD |
| GO_PROTEIN_LOCALIZATION_TO_LYSOSOME | 3.3e-06 | 4.7e-05 | 1229 | 38 | 8 | CD81,LAMP2,MEAK7,NCOA4,RAB7A,RTN4,SCARB2,ZFYVE16 |
| GO_INTERACTION_WITH_HOST | 3.5e-06 | 4.9e-05 | 1229 | 204 | 18 | CD81,CHMP2A,CTNNB1,CTSB,CXCR4,EFNB3,EPS15,HYAL3,INSR,ITGAV,ITGB1,PC,RAB7A,SCARB2,TNFRSF14,TRIM21,TRIM35,ULK1 |
| GO_MAINTENANCE_OF_LOCATION_IN_CELL | 3.5e-06 | 4.9e-05 | 1229 | 94 | 12 | AKAP9,ARHGAP21,DBN1,FTH1,FTL,GAA,HK1,INSIG1,OS9,PINK1,SKP1,TAPT1 |
| GO_PLATELET_DEGRANULATION | 3.5e-06 | 5.0e-05 | 1229 | 128 | 14 | A1BG,APLP2,APP,CD109,CD63,DMTN,FCER1G,HGF,HRG,LAMP2,MAGED2,PROS1,PSAP,STXBP2 |
| GO_REGULATION_OF_LYMPHOCYTE_MIGRATION | 3.5e-06 | 5.0e-05 | 1229 | 64 | 10 | ADAM17,APOD,APP,CRK,MADCAM1,MSN,RHOA,TMEM102,TNFRSF14,WASL |
| GO_REGULATION_OF_BINDING | 3.6e-06 | 5.1e-05 | 1229 | 381 | 26 | APP,CDC42,CRK,CTNNB1,CYLD,DAB2,DAB2IP,DACT1,DNAJB2,GOLGA2,GSK3B,HDAC5,HMOX1,LGALS3,LRP1,MAP2,MAP2K2,PBXIP1,PCSK9,PRKN,PSEN1,SIRT2,STING1,TGFBR1,TRAF6,TTBK2 |
| GO_CIRCULATORY_SYSTEM_PROCESS | 3.7e-06 | 5.2e-05 | 1229 | 554 | 33 | ABR,ADH5,AKAP13,AKAP9,ATP2B4,ATP6AP2,CAMK2D,CDC42,CORO2B,CXCR4,CYB5R3,DSP,FGF13,GAA,GJD3,GNAI2,HMGCR,HMOX1,ITGA1,ITPR2,KCNE1,KCNK6,MYLK3,NOS3,PRCP,RHOA,RNPEP,SCPEP1,SLC2A5,SMAD7,TMEM38A,TRPM4,TRPV4 |
| GO_INTERMEDIATE_FILAMENT_BASED_PROCESS | 3.8e-06 | 5.3e-05 | 1229 | 51 | 9 | CLN8,DSP,DST,KLHL24,MACF1,MTM1,SYNC,SYNM,VIM |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 3.8e-06 | 5.3e-05 | 1229 | 1016 | 50 | ABHD2,ACOX1,ACVR1,AGO4,APP,ATP2B4,BRD2,CCNI,CETN2,CLIC4,CRTAP,CTCFL,CTNNB1,CTSB,HYAL3,IFT27,IGF2R,ITGB1,KDM5A,KDM5B,MAGED2,MAPK1,MDK,MFGE8,MST1R,NCOA1,NOS3,NRIP1,PLPP1,PSG4,PSG5,PSG7,PSG9,REC8,SGPL1,SIRT2,SKIL,SLC26A6,SLC38A2,SPANXB1,STAT5B,STOX2,TGFBR1,TPGS1,TUT7,UBE2B,UBR2,USP9Y,VIPAS39,ZMIZ1 |
| GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 3.8e-06 | 5.3e-05 | 1229 | 51 | 9 | CYLD,DACT1,DUSP3,HIPK3,IGBP1,PINK1,PRKN,SIRPA,TAOK3 |
| GO_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS | 3.9e-06 | 5.4e-05 | 1229 | 95 | 12 | AKR1C3,CYP51A1,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,INSIG1,LSS,SC5D,SCD,STARD4 |
| GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | 4.0e-06 | 5.6e-05 | 1229 | 186 | 17 | CYLD,DAB2IP,DACT1,DUSP3,EFNA1,HIPK3,HMGCR,IGBP1,INPP5K,PINK1,PPEF2,PRKN,PTPRR,RAPGEF1,SIRPA,SMPD1,TAOK3 |
| GO_AMINOGLYCAN_CATABOLIC_PROCESS | 4.1e-06 | 5.6e-05 | 1229 | 65 | 10 | ACAN,CEMIP,CHP1,CSPG4,CTBS,DCN,GALNS,GNS,HYAL3,SDC2 |
| GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS | 4.1e-06 | 5.6e-05 | 1229 | 248 | 20 | ABHD2,AKAP13,AKR1C3,ASS1,CALCOCO1,CREBRF,CTNNB1,DAB2,FBXO32,LBH,NCOA1,NCOA4,NCOR2,NR4A1,NRIP1,PLPP1,RHOA,RNF14,TRIP4,WBP2 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | 4.1e-06 | 5.7e-05 | 1229 | 337 | 24 | APP,CTDP1,CTNNA1,CTNNB1,DMTN,EFNA1,EFNB3,FGF13,GDI1,GSK3B,KANK1,LRP1,MAP2,PLXNA3,PMP22,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C,SIRT2,TRPV4,VIM,ZHX2 |
| GO_NEGATIVE_REGULATION_OF_JNK_CASCADE | 4.1e-06 | 5.6e-05 | 1229 | 39 | 8 | CYLD,DACT1,DUSP3,HIPK3,PINK1,PRKN,SIRPA,TAOK3 |
| GO_REGULATION_OF_BODY_FLUID_LEVELS | 4.1e-06 | 5.7e-05 | 1229 | 506 | 31 | ACTG1,ADCY2,CAPZB,CDC42,CORO2B,DGKD,DMTN,ELOVL1,FAP,FCER1G,GNAI2,GNAS,HRG,ILK,INPP5K,ITPR2,MAFK,MAPK1,MICAL1,MYL12A,NCOA1,NCOR2,NOS3,P2RX6,PHF21A,PRCP,PROS1,SLC22A4,STAT5B,TRPV4,YWHAZ |
| GO_CARBOHYDRATE_TRANSPORT | 4.2e-06 | 5.7e-05 | 1229 | 148 | 15 | AQP9,CLTCL1,CREBL2,INPP5K,INSR,MFSD12,RAB4B,RHOQ,RTN2,SLC17A5,SLC26A6,SLC2A5,SLC2A6,SLC37A1,SORBS1 |
| GO_LIPOPROTEIN_METABOLIC_PROCESS | 4.2e-06 | 5.8e-05 | 1229 | 130 | 14 | APOC1,APOD,CTSD,GLUL,ITGAV,LRP1,PCSK9,PIGG,WDR45,WIPI1,ZDHHC1,ZDHHC17,ZDHHC2,ZDHHC7 |
| GO_SEX_DIFFERENTIATION | 4.2e-06 | 5.7e-05 | 1229 | 270 | 21 | AGO4,AKR1C3,ARID5B,CTNNA1,CTNNB1,DHCR24,HMGCS1,HYAL3,IDH1,INSR,KDM5A,NCOA1,NCOA4,NOS3,NRIP1,REC8,SCX,SGPL1,STAT5B,TGFBR1,WDR19 |
| GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | 4.3e-06 | 5.9e-05 | 1229 | 96 | 12 | ARPC3,BAIAP2,C15orf62,CDC42EP2,CORO1B,CYFIP1,GMFG,MYO1C,RHOA,SNX9,WASHC2C,WASL |
| GO_BONE_MORPHOGENESIS | 4.4e-06 | 6.1e-05 | 1229 | 113 | 13 | ANXA6,COL13A1,COL6A1,COL6A2,GLG1,GNAS,INSIG1,LTBP3,MATN3,RAB23,SCX,THBS3,TRPV4 |
| GO_ENDOSOME_TO_LYSOSOME_TRANSPORT | 4.5e-06 | 6.2e-05 | 1229 | 52 | 9 | DENND3,LYST,MTM1,RAB7A,RILP,STX8,UBXN6,VIPAS39,VPS11 |
| GO_RUFFLE_ORGANIZATION | 4.5e-06 | 6.2e-05 | 1229 | 52 | 9 | CORO1B,CYFIP1,EPS8L1,EPS8L2,INPP5K,KANK1,PLEKHM1,RHOG,WDPCP |
| GO_CELL_CELL_JUNCTION_ORGANIZATION | 4.7e-06 | 6.3e-05 | 1229 | 188 | 17 | AJM1,CDC42,CDH9,CTNNA1,CTNNB1,DSP,GJD3,MYO1C,NUMB,PATJ,PIP5K1C,RAB8B,RHOA,RHOC,SMAD7,TGFBR1,TRPV4 |
| GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 4.7e-06 | 6.4e-05 | 1229 | 363 | 25 | APLP2,APP,CHM,CP,CRTAP,CST3,CUL7,DCAF6,DNAJC3,FBXL12,FBXO32,FN3K,HIF3A,LAMC1,MATN3,MFGE8,NUCB1,PCSK9,PNPLA2,SDC2,SKP1,SPARCL1,SPSB3,VIPAS39,WDTC1 |
| GO_REGULATION_OF_T_CELL_ACTIVATION | 5.0e-06 | 6.8e-05 | 1229 | 318 | 23 | CD276,CD81,CDC42,CTNNB1,CYLD,DUSP3,EFNB3,GPNMB,LGALS3,MAP3K8,MDK,NDFIP1,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,TNFRSF14,TNFSF4,TRAF6,TWSG1,VNN1,ZMIZ1 |
| GO_RESPONSE_TO_METAL_ION | 5.0e-06 | 6.7e-05 | 1229 | 364 | 25 | ACO1,AKR1C3,ANXA11,APP,AQP9,ASS1,ATP13A2,CAMK2D,CLIC4,CPNE3,CYBRD1,DMTN,EIF2AK3,FIBIN,GDI1,HMOX1,IQGAP1,MAP1LC3A,MAPK1,MCOLN1,NQO1,PRKN,S100A13,SLC39A13,SYT15 |
| GO_REGULATION_OF_SYSTEM_PROCESS | 5.1e-06 | 6.8e-05 | 1229 | 614 | 35 | AKAP9,ANXA6,APP,ATP2B4,BAIAP2,CALCRL,CAMK2D,CORO2B,CTDP1,DSP,EIF2AK3,FBXO32,FGF13,GAA,GALR1,GJD3,GNAI2,GNAS,GRIN2D,HGF,INPP5K,ITPR2,KCNE1,KCNK6,LMCD1,MYL5,NOS3,RAB11FIP5,RAB8B,RHOA,SMAD7,TMEM38A,TRPM4,TSHZ3,ZFHX2 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE | 5.2e-06 | 7.0e-05 | 1229 | 6 | 4 | DMTN,GDI1,INPP5K,KCNE1 |
| GO_REGULATION_OF_RUFFLE_ASSEMBLY | 5.2e-06 | 7.0e-05 | 1229 | 29 | 7 | CYFIP1,EPS8L1,EPS8L2,KANK1,PLEKHM1,RHOG,WDPCP |
| GO_HEART_DEVELOPMENT | 5.3e-06 | 7.0e-05 | 1229 | 589 | 34 | ACAN,ACVR1,AKAP13,CALCRL,CDC42,CERT1,CRELD1,CTDP1,CTNNB1,DSP,EFNA1,FOXL1,GAA,HECTD1,ILK,INSR,ITGB1,MAP2K2,MAPK1,MYLK3,NOS3,NOTCH2,PAX8,PDLIM7,PSEN1,RTN4,SAV1,SCX,SGCB,SMAD7,TGFBR1,TSC2,UBE4B,ZMIZ1 |
| GO_PROTEIN_KINASE_B_SIGNALING | 5.3e-06 | 7.0e-05 | 1229 | 274 | 21 | AKR1C3,CAVIN3,CHI3L1,HGF,ILK,INPP5K,INSR,ITGB1,MST1R,MTM1,PHLDA3,PINK1,PPP2R5B,RAPGEF1,RCN3,RHOG,RRAS,RTN4,SIRT2,TGFBR1,TSC2 |
| GO_COLLAGEN_METABOLIC_PROCESS | 5.4e-06 | 7.2e-05 | 1229 | 115 | 13 | COL13A1,CST3,CTSB,CTSD,FAP,FURIN,ITGB1,PEPD,PLOD2,RCN3,SCX,VIM,VIPAS39 |
| GO_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT | 5.4e-06 | 7.2e-05 | 1229 | 115 | 13 | ANO10,BEST1,CLCN3,CLCN6,CLCN7,CLIC4,SLC12A4,SLC12A6,SLC13A1,SLC26A11,SLC26A4,SLC26A6,SLC37A1 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 5.4e-06 | 7.2e-05 | 1229 | 777 | 41 | CHMP2A,CRK,CTDP1,CTSB,CXCR4,CYLD,DAB2IP,ERCC6,FBXL2,FCER1G,GRAMD4,GRN,HYAL3,IGF2R,INPP5K,ITGAV,JAK1,LRSAM1,LY96,MAPKAPK2,MICA,NLRP10,OPTN,PC,PJA2,PRKN,RAB7A,RFTN1,RTN4,SHFL,SIRT2,SKP1,SLAMF6,STAT5B,STING1,TANK,TOP2B,TRAF6,TRIM21,TRIM35,WDFY1 |
| GO_PROTEIN_DEPHOSPHORYLATION | 5.6e-06 | 7.4e-05 | 1229 | 320 | 23 | CTDP1,CTDSP2,DUSP3,GNAI2,GSK3B,IGBP1,ITGA1,LGALS3,MTM1,MTMR3,NUAK1,PINK1,PLPP1,PPEF2,PPM1N,PPP2R5B,PTPN21,PTPRD,PTPRH,PTPRR,SHOC2,SMPD1,SWAP70 |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 5.8e-06 | 7.7e-05 | 1229 | 671 | 37 | ACAN,ACAT1,ACOT8,ACSL1,ACSS2,ADCY2,B3GNT2,B3GNT9,CDA,CEMIP,CHP1,CHPF,CSPG4,CTNNB1,DCN,ELOVL1,FOXL1,GALNT3,GK,GOLGA2,MAN1A2,MAN2A1,MAN2A2,MPC2,MT-ATP6,MT-ATP8,NAGK,PIGG,PINK1,PMM1,PSEN1,SCD,SDC2,SOAT1,TMEM165,TMEM59,UST |
| GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | 5.8e-06 | 7.6e-05 | 1229 | 152 | 15 | AACS,AKAP9,APP,AQP9,ASS1,DMTN,HMGCS1,INPP5K,ITPR2,KCNE1,P2RX6,RAPGEF1,SLC26A6,TMEM38A,TRPM4 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 6.0e-06 | 7.9e-05 | 1229 | 134 | 14 | AVIL,CAPG,CAPZB,CDC42,DACT1,DMTN,GSK3B,KANK1,MAP2,MYADM,SIRT2,SPTBN1,ULK1,WASHC2C |
| GO_PROTEIN_AUTOPHOSPHORYLATION | 6.0e-06 | 7.9e-05 | 1229 | 233 | 19 | AAK1,ATP13A2,CAMK2D,CHP1,EIF2AK3,FRK,GPNMB,GSK3B,INSR,IQGAP1,MAP2K2,MAP3K10,MAPKAPK2,PEAK1,PINK1,PPP2R5B,TAOK3,TRPM7,ULK1 |
| GO_REGULATION_OF_CELL_ACTIVATION | 6.0e-06 | 7.9e-05 | 1229 | 619 | 35 | ABR,APLF,CD276,CD81,CDC42,CTNNB1,CYLD,DMTN,DUSP3,EFNB3,FCER1G,GPNMB,GRN,HMOX1,HRG,IGHV3-74,LGALS3,MAP3K8,MDK,MICA,NDFIP1,NOS3,PJA2,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,STXBP2,TNFRSF14,TNFSF4,TRAF6,TWSG1,VNN1,ZMIZ1 |
| GO_REGULATION_OF_TOR_SIGNALING | 6.0e-06 | 7.9e-05 | 1229 | 99 | 12 | CASTOR2,CASTOR3,FNIP1,LAMTOR3,MTM1,RRAGC,SIK3,TBC1D7,TMEM127,TSC2,UBR2,WDR59 |
| GO_RESPONSE_TO_ACID_CHEMICAL | 6.1e-06 | 8.0e-05 | 1229 | 345 | 24 | AACS,ACSL1,AKR1C3,ASS1,ATP2B4,BAIAP2,CASTOR2,CASTOR3,COL6A1,EEF2,HSD17B2,IGF2R,KLF2,LAMTOR3,MEAK7,NCOA1,NQO1,PINK1,RHOA,RRAGC,SCD,TNFSF4,UBR2,WNT5B |
| GO_RUFFLE_ASSEMBLY | 6.1e-06 | 7.9e-05 | 1229 | 41 | 8 | CYFIP1,EPS8L1,EPS8L2,INPP5K,KANK1,PLEKHM1,RHOG,WDPCP |
| GO_NEGATIVE_REGULATION_OF_AXONOGENESIS | 6.2e-06 | 8.1e-05 | 1229 | 68 | 10 | EFNB3,FGF13,GDI1,MAP2,PLXNA3,PSEN1,RHOA,RTN4,SEMA4B,SEMA6C |
| GO_RESPONSE_TO_MITOCHONDRIAL_DEPOLARISATION | 6.3e-06 | 8.2e-05 | 1229 | 20 | 6 | AMBRA1,ATG13,OPTN,PINK1,PRKN,SQSTM1 |
| GO_ACTIN_CYTOSKELETON_REORGANIZATION | 6.6e-06 | 8.6e-05 | 1229 | 100 | 12 | ARAP1,AUTS2,BAIAP2,BCAS3,CDC42,DMTN,GMFG,MDK,NEDD9,NOTCH2,RHOA,TRPV4 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 6.7e-06 | 8.7e-05 | 1229 | 895 | 45 | ABI1,ACTG1,ARPC3,BAIAP2,C1S,CD276,CD81,CDC42,CRK,CTSB,CYFIP1,CYLD,DAB2IP,DUSP3,FCER1G,FCGRT,GRAMD4,HK1,HRG,IGHV3-74,LGALS3,LY96,MAPK1,MAPKAPK2,MICA,MYO1C,NLRP10,PJA2,PROS1,PSEN1,RAPGEF1,RFTN1,RTN4,SKP1,SLAMF6,SPON2,STAT5B,STING1,STX7,TANK,TNFRSF14,TNFSF4,TRAF6,WASL,WDFY1 |
| GO_SECOND_MESSENGER_MEDIATED_SIGNALING | 6.7e-06 | 8.7e-05 | 1229 | 443 | 28 | ADCY2,ADGRD1,ADGRL4,AKAP13,ATP2B4,CALCRL,CAMK2D,CHP1,CXCR4,DGKD,DMTN,EIF2AK3,GALR1,GNAI2,GNAS,GPR161,GRIN2D,GSK3B,ITPR2,LMCD1,MCOLN1,NFAT5,NOS3,RASD1,TMEM38A,TRPM4,UBE2B,UCN2 |
| GO_CELL_DIVISION | 7.2e-06 | 9.4e-05 | 1229 | 598 | 34 | ANXA11,ARL8A,ARL8B,CCNG1,CDC42,CDK2AP2,CETN2,CHMP1B,CHMP2A,CTDP1,CUL7,DYNC1H1,DYNLT3,FGF13,GNAI2,GOLGA2,KLHDC8B,LATS2,LBH,MARK4,MDK,NEDD9,NUMB,PARD3B,RHOA,RHOC,SH3GLB1,SIRT2,SNX33,SNX9,SPTBN1,SVIL,WASL,ZFYVE26 |
| GO_ACTIN_FILAMENT_DEPOLYMERIZATION | 7.3e-06 | 9.5e-05 | 1229 | 55 | 9 | AVIL,CAPG,CAPZB,DMTN,DSTN,MICAL1,SPTBN1,SWAP70,WASHC2C |
| GO_MITOCHONDRIAL_TRANSPORT | 7.4e-06 | 9.5e-05 | 1229 | 258 | 20 | ALKBH7,ATG13,GSK3B,HEBP2,LEPROT,MICU1,MOAP1,MPC2,MT-ATP6,MT-ATP8,NPEPPS,PINK1,PRKN,PSEN1,RHOT1,SH3GLB1,TMEM102,VPS11,YWHAZ,ZNF205 |
| GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 7.4e-06 | 9.5e-05 | 1229 | 258 | 20 | CHP1,DAB2IP,DNAJC3,DUSP3,GMFG,HIPK3,HMGCR,ILK,INPP5K,LATS2,PIK3IP1,PKIG,PRKN,PSEN1,RUBCN,SH3BP5,SMPD1,SNX6,TAOK3,TSC2 |
| GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 7.4e-06 | 9.5e-05 | 1229 | 258 | 20 | ABI1,ACVR1,ADAM17,APP,CD81,CSPG4,DMTN,EFNA1,ERCC6,HGF,HRG,IQGAP1,LRRK1,NEDD9,PPP2R5B,PSEN1,SH3BP5,SNX6,TMEM102,TNFRSF14 |
| GO_MESENCHYMAL_CELL_DIFFERENTIATION | 7.8e-06 | 1.0e-04 | 1229 | 216 | 18 | ACVR1,CTNNB1,CUL7,DAB2,DAB2IP,EFNA1,GSK3B,HGF,MAPK1,MDK,RTN4,SDCBP,SEMA4B,SEMA6C,SMAD7,TAPT1,TGFBR1,VASN |
| GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | 7.8e-06 | 1.0e-04 | 1229 | 259 | 20 | CD276,CD81,CDC42,CYLD,DMTN,EFNB3,KIFAP3,MAP3K8,MDK,NFAT5,RHOA,SIRPA,SIRPB1,SMAD7,STAT5B,TNFRSF14,TNFSF4,TRAF6,VNN1,ZMIZ1 |
| GO_MITOTIC_CYTOKINESIS | 8.1e-06 | 1.0e-04 | 1229 | 70 | 10 | CHMP1B,CHMP2A,CUL7,KLHDC8B,RHOA,RHOC,SNX33,SNX9,SPTBN1,ZFYVE26 |
| GO_PROTEIN_AUTOUBIQUITINATION | 8.1e-06 | 1.0e-04 | 1229 | 70 | 10 | KLHL24,LRSAM1,PRKN,RNF11,RNF133,RNF146,TRAF6,TRIM21,UBE2B,UBE4B |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 8.1e-06 | 1.0e-04 | 1229 | 423 | 27 | ACAT1,ACOT8,ACSL1,ACSS2,ADCY2,APP,ARNT,ELOVL1,HK1,HMGCR,HMGCS1,INSR,MPC2,MT-ATP6,MT-ATP8,NT5C2,PGM1,PGM2L1,PINK1,PRXL2C,PSEN1,RAB23,RHOA,RHOQ,SCD,SLC2A6,SULT1C2 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II | 8.2e-06 | 1.0e-04 | 1229 | 102 | 12 | CAPZB,CTSD,CTSF,DCTN2,DYNC1H1,FCER1G,KIF3C,KIFAP3,OSBPL1A,RAB7A,RILP,TRAF6 |
| GO_EPHRIN_RECEPTOR_SIGNALING_PATHWAY | 8.6e-06 | 1.1e-04 | 1229 | 86 | 11 | ACTG1,ARPC3,CDC42,CRK,EFNA1,EFNB3,PSEN1,RHOA,SDC2,SDCBP,WASL |
| GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 8.6e-06 | 1.1e-04 | 1229 | 86 | 11 | DAB2IP,DEDD2,GABARAP,HGF,HMOX1,LGALS3,MADD,MOAP1,NOS3,SKIL,TMBIM1 |
| GO_CARBOHYDRATE_CATABOLIC_PROCESS | 9.3e-06 | 1.2e-04 | 1229 | 198 | 17 | APP,ARNT,CTBS,GAA,GK,HK1,INSR,MANBA,NEU1,PGM1,PGM2L1,PRXL2C,PSEN1,RBKS,SCARB2,SLC2A6,TREH |
| GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | 9.4e-06 | 1.2e-04 | 1229 | 219 | 18 | AVIL,CAPG,CAPZB,DMTN,DSTN,FGF13,MAP1B,MICAL1,NCKAP5L,NSF,SHFL,SPEF1,SPTBN1,SWAP70,TRIM54,TRPV4,TTBK2,WASHC2C |
| GO_CELLULAR_RESPONSE_TO_ALCOHOL | 9.6e-06 | 1.2e-04 | 1229 | 87 | 11 | AACS,ADCY2,AKR1C3,CTNNA1,CTNNB1,GRAMD1A,HMGCS1,ITPR2,KLF2,TNFSF4,TP53INP1 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_STARVATION | 9.7e-06 | 1.2e-04 | 1229 | 13 | 5 | GABARAP,GABARAPL2,MAP1LC3A,MAP1LC3B,MAP1LC3B2 |
| GO_POSITIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 9.7e-06 | 1.2e-04 | 1229 | 13 | 5 | DAB2,MAP2,MSN,PRKN,VPS11 |
| GO_RESPONSE_TO_ANTIBIOTIC | 9.7e-06 | 1.2e-04 | 1229 | 331 | 23 | AACS,ADCY2,CRK,EEF2,HGF,HMGCR,HMOX1,HYAL3,ITPR2,JAK1,KDM5B,KLF2,MAP1LC3A,MT-ND5,MT-ND6,NQO1,OSER1,PINK1,PSAP,RHOA,SIRPA,TP53INP1,ZNF277 |
| GO_FATTY_ACID_CATABOLIC_PROCESS | 1.0e-05 | 1.3e-04 | 1229 | 104 | 12 | ACAT1,ACAT2,ACOT8,ACOX1,DECR1,EHHADH,HADHA,HADHB,LPIN1,LPIN2,PHYH,PLA2G15 |
| GO_FATTY_ACID_METABOLIC_PROCESS | 1.0e-05 | 1.3e-04 | 1229 | 380 | 25 | AACS,ACAT1,ACAT2,ACOT8,ACOX1,ACSL1,ACSS2,ADH5,AKR1C3,ALKBH7,APOC1,DECR1,EHHADH,ELOVL1,HADHA,HADHB,INSIG1,LPIN1,LPIN2,MSMO1,PHYH,PLA2G15,SCD,SGPL1,WDTC1 |
| GO_LYSOSOME_LOCALIZATION | 1.0e-05 | 1.3e-04 | 1229 | 72 | 10 | ARL8B,BORCS6,FCER1G,HMOX1,PLEKHM1,PLEKHM2,S100A13,SNAP23,SPAG9,STXBP2 |
| GO_PROTON_TRANSMEMBRANE_TRANSPORT | 1.0e-05 | 1.3e-04 | 1229 | 159 | 15 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CHP1,CLCN3,COX6A1,COX6C,MT-ATP6,MT-ATP8,SLC15A4,SLC17A5,SLC2A6,TMCO3 |
| GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 1.0e-05 | 1.3e-04 | 1229 | 286 | 21 | AKR1C3,ASS1,ATP2B4,CTNS,FBLN5,GNAI2,INSR,KLF2,MT-ND2,NCF2,NOS3,NQO1,PINK1,PLA2R1,PRCP,PRDX5,PRKN,RHOA,SIRPA,SIRT2,ZNF205 |
| GO_CHONDROCYTE_DIFFERENTIATION | 1.1e-05 | 1.4e-04 | 1229 | 123 | 13 | ACAN,ANXA6,COL6A1,COL6A2,CTNNB1,EIF2AK3,GLG1,LTBP3,MATN3,MDK,SCX,TGFBR1,WNT5B |
| GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 1.1e-05 | 1.4e-04 | 1229 | 141 | 14 | ACVR1,CTNNB1,CUL7,DAB2,DAB2IP,EFNA1,GSK3B,HGF,MDK,RTN4,SDCBP,SMAD7,TGFBR1,VASN |
| GO_MUSCLE_TISSUE_DEVELOPMENT | 1.1e-05 | 1.4e-04 | 1229 | 406 | 26 | ACVR1,AKAP13,CDC42,CTDP1,CTNNB1,DCN,DSP,EEF2,GPCPD1,HMGCR,ITGB1,MAPK1,MTM1,MYL6,MYL6B,MYLK3,RHOA,SAV1,SCX,SGCB,SIRT2,SMAD7,SRPK3,SVIL,TGFBR1,UBE4B |
| GO_PHAGOSOME_MATURATION | 1.1e-05 | 1.3e-04 | 1229 | 44 | 8 | ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,RAB31,RAB32,RAB43,RAB7A |
| GO_POSITIVE_REGULATION_OF_AXONOGENESIS | 1.1e-05 | 1.3e-04 | 1229 | 88 | 11 | CYFIP1,DBN1,GDI1,ILK,LRP1,MACF1,MAP1B,MAP2K2,PLXNA3,RHOA,SKIL |
| GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 1.1e-05 | 1.4e-04 | 1229 | 455 | 28 | ABR,APLF,C1S,CD81,CRK,DNASE1,ERCC6,FCER1G,FCGRT,GRN,HK1,HMOX1,LGALS3,MICA,NDFIP1,PROS1,RAPGEF1,SLAMF6,SMAD7,SPON2,STAT5B,STING1,STX7,STXBP2,TNFRSF14,TNFSF4,TRAF6,TRPM4 |
| GO_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY | 1.3e-05 | 1.6e-04 | 1229 | 59 | 9 | CTNNB1,DAB2,NCOA1,NCOA4,NCOR2,NRIP1,PLPP1,RHOA,RNF14 |
| GO_PROTEIN_HOMOOLIGOMERIZATION | 1.3e-05 | 1.6e-04 | 1229 | 314 | 22 | ACAT1,ANXA6,CDA,CHMP2A,DECR1,DGKD,EIF2AK3,FCER1G,GLUL,GOLGA2,HMOX1,KCTD10,KCTD21,MCOLN1,MICU1,MIEF2,OSBPL2,RHOC,SCUBE3,SHARPIN,TRPM4,UPB1 |
| GO_TISSUE_HOMEOSTASIS | 1.3e-05 | 1.6e-04 | 1229 | 224 | 18 | ACTG1,ATP6AP1,BBS12,CLN8,CTNNB1,ERCC6,GNAS,LCA5,LRRK1,LTBP3,NOS3,PLEKHM1,RCN3,RP1L1,SCX,TP53INP2,TPP1,TRAF6 |
| GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE | 1.4e-05 | 1.7e-04 | 1229 | 247 | 19 | ADH5,FBLN5,HGF,HMOX1,ITPR2,KLF2,MAP1LC3A,NOS3,NQO1,OSER1,PINK1,PRDX5,PRKN,PRXL2C,PSAP,SIRPA,TP53INP1,TXNRD1,ZNF277 |
| GO_TISSUE_MORPHOGENESIS | 1.4e-05 | 1.7e-04 | 1229 | 670 | 36 | ACVR1,ADAM17,CD151,CDC42,CLIC4,COL6A1,COL6A2,CTNNB1,CXCR4,DAB2,DACT1,DSP,EXOC4,FOXL1,HGF,ILK,ITGB1,KDM5B,MATN3,MDK,MSN,NOS3,NOTCH2,OPHN1,PAX8,PSEN1,RHOA,RHOC,SCX,SMAD7,TGFBR1,TRAF6,TSC2,TWSG1,TXNRD1,UBE4B |
| GO_TRANSITION_METAL_ION_TRANSPORT | 1.4e-05 | 1.7e-04 | 1229 | 125 | 13 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,CP,FTH1,FTL,HRG,MCOLN1,REP15,SLC31A2,SLC39A13 |
| GO_NEGATIVE_REGULATION_OF_TOR_SIGNALING | 1.5e-05 | 1.8e-04 | 1229 | 46 | 8 | CASTOR2,CASTOR3,FNIP1,MTM1,TBC1D7,TMEM127,TSC2,UBR2 |
| GO_ORGANIC_ACID_CATABOLIC_PROCESS | 1.5e-05 | 1.8e-04 | 1229 | 271 | 20 | ACAT1,ACAT2,ACOT8,ACOX1,ALDH6A1,ATP2B4,CEMIP,CHP1,DECR1,EHHADH,GLUL,HADHA,HADHB,HYAL3,LPIN1,LPIN2,NAGK,NOS3,PHYH,PLA2G15 |
| GO_PROTEIN_STABILIZATION | 1.5e-05 | 1.9e-04 | 1229 | 185 | 16 | AAK1,CAMLG,CHP1,CREBL2,CRTAP,EFNA1,GRN,LAMP2,PEX6,PINK1,PRKN,RTN4,SAV1,SMAD7,TMEM88,UBE2B |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1.5e-05 | 1.8e-04 | 1229 | 463 | 28 | ACAT1,ACOT8,ACSL1,ACSS2,ADCY2,APP,ARNT,ELOVL1,HK1,HMGCR,HMGCS1,INSR,MPC2,MT-ATP6,MT-ATP8,NOS3,NT5C2,PGM1,PGM2L1,PINK1,PRXL2C,PSEN1,RAB23,RHOA,RHOQ,SCD,SLC2A6,SULT1C2 |
| GO_REGULATION_OF_FILOPODIUM_ASSEMBLY | 1.5e-05 | 1.8e-04 | 1229 | 46 | 8 | ARAP1,BCAS3,CAPZB,CDC42,DMTN,RHOQ,TGFBR1,WASL |
| GO_RESPONSE_TO_HYDROGEN_PEROXIDE | 1.5e-05 | 1.8e-04 | 1229 | 145 | 14 | CRK,EEF2,HGF,HMOX1,KLF2,MAP1LC3A,MT-ND5,MT-ND6,NQO1,OSER1,PINK1,PSAP,SIRPA,ZNF277 |
| GO_COLLAGEN_CATABOLIC_PROCESS | 1.7e-05 | 2.1e-04 | 1229 | 47 | 8 | COL13A1,CST3,CTSB,CTSD,FAP,FURIN,ITGB1,PEPD |
| GO_INORGANIC_ANION_TRANSPORT | 1.7e-05 | 2.0e-04 | 1229 | 166 | 15 | ANO10,BEST1,CLCN3,CLCN6,CLCN7,CLIC4,LRRC8A,SLC12A4,SLC12A6,SLC13A1,SLC26A11,SLC26A4,SLC26A6,SLC37A1,SLC4A3 |
| GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | 1.7e-05 | 2.1e-04 | 1229 | 76 | 10 | BAIAP2,CUL7,CUX1,CYFIP1,DAB2IP,DBN1,ILK,IQGAP1,PSEN1,PTPRD |
| GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 1.8e-05 | 2.2e-04 | 1229 | 167 | 15 | AKR1C3,CRK,FBLN5,HGF,KLF2,MAP1LC3A,MAPK1,NOS3,NQO1,OSER1,PINK1,PRDX5,PSAP,SIRPA,ZNF277 |
| GO_MICROTUBULE_BUNDLE_FORMATION | 1.8e-05 | 2.2e-04 | 1229 | 93 | 11 | CCSER2,CHP1,MAP1B,MAP2,MARK4,NCKAP5L,RP1L1,RSPH9,TPGS1,TTLL3,UBE2B |
| GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 1.8e-05 | 2.1e-04 | 1229 | 147 | 14 | APLF,CD81,CRK,FCER1G,FCGRT,MICA,NDFIP1,SLAMF6,SMAD7,STAT5B,STX7,TNFSF4,TRAF6,TRPM4 |
| GO_VESICLE_MEDIATED_TRANSPORT_TO_THE_PLASMA_MEMBRANE | 1.8e-05 | 2.2e-04 | 1229 | 93 | 11 | EXOC1,EXOC4,EXOC6B,MACF1,NSF,OPTN,RAB31,SPTBN1,STX3,VPS26C,WASHC2C |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 1.9e-05 | 2.2e-04 | 1229 | 791 | 40 | ACSL1,ADAM17,CAMK2D,CDC42,CREBRF,CRK,CSF2RA,CXCR4,CYLD,FCER1G,GBP2,HGF,HMOX1,IFI35,IFIT3,IL17RA,ILK,IRF9,ITGB1,JAK1,MADD,MAP3K8,MSN,MST1R,OSMR,PRKN,RAPGEF1,SHARPIN,SKP1,SQSTM1,STAT2,STAT5B,STX3,TNFRSF14,TNFSF4,TOLLIP,TRAF6,TRIM21,VIM,YWHAZ |
| GO_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 1.9e-05 | 2.3e-04 | 1229 | 129 | 13 | CALCOCO1,CTNNB1,DAB2,LBH,NCOA1,NCOA4,NCOR2,NRIP1,PLPP1,RHOA,RNF14,TRIP4,WBP2 |
| GO_REGULATION_OF_DEPHOSPHORYLATION | 1.9e-05 | 2.2e-04 | 1229 | 209 | 17 | CHP1,GNAI2,GSK3B,IGBP1,INPP5K,IQGAP1,ITGA1,LGALS3,MTMR3,NUAK1,PINK1,PPP2R5B,SHOC2,SMG6,SMPD1,SWAP70,ZFYVE1 |
| GO_AGING | 2.0e-05 | 2.4e-04 | 1229 | 323 | 22 | APOD,APP,ASS1,CLN8,CTNNA1,DCN,EEF2,FOXO4,HMGCR,ILK,LITAF,LRP1,MAPK1,MT-ATP6,NQO1,NUAK1,PLA2R1,PSEN1,TIMP2,YPEL3,ZMIZ1,ZNF277 |
| GO_NEGATIVE_REGULATION_OF_NEURON_DEATH | 2.0e-05 | 2.4e-04 | 1229 | 210 | 17 | AMBRA1,ATP13A2,CLN3,CTNNB1,GPNMB,GRN,GSK3B,HMOX1,ILK,LRP1,MDK,MEAK7,PINK1,PRKN,PSEN1,RHOA,SNX6 |
| GO_AMINOGLYCAN_METABOLIC_PROCESS | 2.1e-05 | 2.5e-04 | 1229 | 169 | 15 | ACAN,B3GNT2,B3GNT9,CEMIP,CHP1,CHPF,CSPG4,CTBS,DCN,GALNS,GNS,HGF,HYAL3,SDC2,UST |
| GO_OSSIFICATION | 2.1e-05 | 2.5e-04 | 1229 | 396 | 25 | ACVR1,ATP6AP1,COL13A1,COL6A1,CTNNB1,EIF2AK3,GNAS,GPNMB,HGF,IGSF10,ILK,LTBP3,MAPK1,MDK,PDLIM7,RHOA,RRAS2,RRBP1,SCX,TAPT1,THBS3,TP53INP2,TRAF6,TRPM4,TWSG1 |
| GO_RECEPTOR_INTERNALIZATION | 2.1e-05 | 2.5e-04 | 1229 | 112 | 12 | CALCRL,CD63,CD81,EPS15,FCER1G,ITGB1,LRP1,NUMB,OPHN1,PCSK9,RAB31,SDCBP |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 2.2e-05 | 2.6e-04 | 1229 | 1146 | 52 | ABTB1,ACAT1,ACO1,ACOT8,ACSL1,ACSS2,AGO4,APP,ASS1,ATP6AP2,CERT1,CLN8,CPD,CPQ,CTNS,CYFIP1,DNAJC3,EEF1A1P5,EEF2,EFNA1,EIF1AY,EIF2AK3,EIF4E3,ELOVL1,ETHE1,FURIN,HMGCS1,IDH1,MAPK1,MPC2,NEU1,NPEPPS,OPLAH,PC,PINK1,PLA2G15,PSAP,PSEN1,RHOA,RPS27L,RRBP1,SAMD8,SCD,SECISBP2L,SGPL1,SHFL,SMPD1,SPTLC1,TPP1,TRNAU1AP,VIM,VNN1 |
| GO_CYTOKINESIS | 2.2e-05 | 2.6e-04 | 1229 | 170 | 15 | ANXA11,CDC42,CETN2,CHMP1B,CHMP2A,CUL7,KLHDC8B,RHOA,RHOC,SH3GLB1,SNX33,SNX9,SPTBN1,SVIL,ZFYVE26 |
| GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 2.2e-05 | 2.6e-04 | 1229 | 278 | 20 | AKR1C3,ARNT,CALCOCO1,CTNNB1,CYLD,DAB2,LBH,NCOA1,NCOA4,NCOR2,NR4A1,NRIP1,PLPP1,PRCP,RHOA,RNF14,STING1,TRAF6,TRIP4,WBP2 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 2.2e-05 | 2.6e-04 | 1229 | 853 | 42 | ABHD2,ACOX1,ACVR1,AGO4,APP,ATP2B4,BRD2,CCNI,CETN2,CREBRF,CRTAP,CTCFL,CTNNB1,CTSB,HYAL3,IFT27,IGF2R,ITGB1,KDM5A,MAPK1,MDK,NCOA1,NCOR2,NOS3,NRIP1,PLPP1,REC8,SGPL1,SIRT2,SKIL,SLC26A6,SPANXB1,STAT5B,STOX2,TGFBR1,TPGS1,TUT7,UBE2B,UBR2,USP9Y,VIPAS39,ZMIZ1 |
| GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 2.2e-05 | 2.6e-04 | 1229 | 150 | 14 | DAB2IP,DCN,FBXL2,HGF,INSR,MAPK1,NYAP1,PIK3IP1,PIP4K2C,PIP5K1C,PPP2R5B,PRR5L,SIRT2,TSC2 |
| GO_POSITIVE_REGULATION_OF_VACUOLE_ORGANIZATION | 2.2e-05 | 2.6e-04 | 1229 | 15 | 5 | GRN,LRSAM1,PIP4K2C,SH3GLB1,ULK1 |
| GO_ESTABLISHMENT_OF_GOLGI_LOCALIZATION | 2.3e-05 | 2.7e-04 | 1229 | 8 | 4 | ARHGAP21,CDC42,COPG1,YWHAZ |
| GO_NEGATIVE_REGULATION_OF_CELL_MOTILITY | 2.3e-05 | 2.7e-04 | 1229 | 350 | 23 | ABHD2,ABR,APOD,CLIC4,CORO1B,CRK,CTNNA1,DAB2IP,DCN,DUSP3,HDAC5,HMOX1,HRG,ILK,KANK1,LIMCH1,LRP1,PTPRR,RHOA,RRAS,SMAD7,TP53INP1,WASL |
| GO_REGULATION_OF_CHOLESTEROL_METABOLIC_PROCESS | 2.3e-05 | 2.7e-04 | 1229 | 63 | 9 | CYP51A1,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,LSS,SC5D,SCD |
| GO_PROTEIN_TARGETING_TO_MEMBRANE | 2.4e-05 | 2.8e-04 | 1229 | 192 | 16 | CEMIP,CHM,CHP1,DMTN,EXOC4,GDI1,INPP5K,KCNE1,MIEF2,MYO1C,RAB8B,SDCBP,SRP14,ZDHHC1,ZDHHC2,ZDHHC7 |
| GO_TRANSFERRIN_TRANSPORT | 2.4e-05 | 2.8e-04 | 1229 | 36 | 7 | ATP6AP1,ATP6V0E1,ATP6V1C1,ATP6V1D,ATP6V1E1,MCOLN1,REP15 |
| GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION | 2.5e-05 | 2.9e-04 | 1229 | 114 | 12 | AKAP9,CSNK1D,FGF13,GOLGA2,MAP1B,MAP2,MAP7D3,NCKAP5L,SPEF1,TRIM54,TRPV4,TTBK2 |
| GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | 2.5e-05 | 2.9e-04 | 1229 | 114 | 12 | ACAN,B3GNT2,CEMIP,CHP1,CHPF,CSPG4,DCN,GALNS,GNS,HGF,HYAL3,UST |
| GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 2.5e-05 | 2.9e-04 | 1229 | 96 | 11 | ABI1,ARNT,BAIAP2,CDC42,CRK,CYFIP1,DAB2IP,ITGAV,MAPKAPK2,NCF2,RHOA |
| GO_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | 2.5e-05 | 2.9e-04 | 1229 | 214 | 17 | ACTG1,APBA2,BTBD8,BTBD9,CTNNB1,CYFIP1,EPS15,FCHO2,GSK3B,KIAA1109,NUMB,OPHN1,PIP5K1C,PSEN1,SNAP23,STX3,STXBP5 |
| GO_INOSITOL_LIPID_MEDIATED_SIGNALING | 2.6e-05 | 3.0e-04 | 1229 | 193 | 16 | DAB2IP,DCN,EXOC1,FBXL2,HGF,INSR,MAPK1,NYAP1,PIK3IP1,PIP4K2C,PIP5K1C,PPP2R5B,PRR5L,RHOA,SIRT2,TSC2 |
| GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 2.6e-05 | 3.0e-04 | 1229 | 664 | 35 | ADAM17,AKAP9,APP,CDC42,CDK2AP2,CETN2,CHMP1B,CHMP2A,CSNK1D,CTDSP2,CTNNB1,CUL7,CYLD,DACT1,DCTN2,DUSP3,DYNC1H1,DYNLT3,FAP,FOXO4,GPNMB,HECA,INSR,IQGAP1,NEK11,OFD1,RPS27L,SDCBP,SIRT2,SKP1,STAT5B,TAOK3,TIMP2,TOP2B,TRIM35 |
| GO_REGULATION_OF_RECEPTOR_RECYCLING | 2.6e-05 | 3.0e-04 | 1229 | 25 | 6 | ARAP1,EPS15,NSF,OPTN,PCSK9,PSEN1 |
| GO_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 2.7e-05 | 3.1e-04 | 1229 | 282 | 20 | B3GNT2,B3GNT9,DYSF,GAA,GK,GSK3B,HK1,IDH1,INPP5K,INSR,MST1,NAGK,PGM1,PGM2L1,PPP1R3F,PRKN,RBKS,SCARB2,SORBS1,TREH |
| GO_NEURON_PROJECTION_GUIDANCE | 2.7e-05 | 3.1e-04 | 1229 | 282 | 20 | APP,B3GNT2,CXCR4,CYFIP1,DOK4,EFNA1,EFNB3,LRP1,MAPK1,NRCAM,OPHN1,PALLD,PDLIM7,PLXNA3,RHOG,SEMA4B,SEMA6C,SPTBN1,ZSWIM4,ZSWIM8 |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 2.7e-05 | 3.1e-04 | 1229 | 353 | 23 | ACOT8,ACSS2,AKR1C3,APOC1,ASS1,ATP2B4,CEMIP,CSPG4,CYP8B1,DCN,ELOVL1,GLUL,INSIG1,OSBPL1A,OSBPL2,PLOD2,SCD,SERINC3,SERINC5,STARD4,UPB1,UST,WDTC1 |
| GO_REGULATION_OF_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 2.8e-05 | 3.1e-04 | 1229 | 153 | 14 | CAMLG,CSNK1D,DAB2,DNAJB2,GSK3B,MTM1,PRKN,PSEN1,RNF14,SDCBP,SIRT2,SMAD7,UBXN1,ZER1 |
| GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | 2.9e-05 | 3.3e-04 | 1229 | 216 | 17 | AKR1C3,APP,ATP13A2,CAMK2D,CLIC4,CPNE3,CRK,DMTN,EIF2AK3,HMOX1,IQGAP1,MAP1LC3A,MAPK1,MCOLN1,NQO1,PRKN,SYT15 |
| GO_MEMBRANE_INVAGINATION | 2.9e-05 | 3.3e-04 | 1229 | 134 | 13 | CDC42,CHMP2A,FCER1G,FCHO2,IGHV3-74,MFGE8,RAB31,RHOA,RHOG,SNX33,SNX9,XKR8,XKR9 |
| GO_ADHERENS_JUNCTION_ORGANIZATION | 3.0e-05 | 3.4e-04 | 1229 | 65 | 9 | CDC42,CDH9,CTNNA1,CTNNB1,DSP,NUMB,PIP5K1C,RAB8B,SMAD7 |
| GO_EXTRACELLULAR_MATRIX_DISASSEMBLY | 3.0e-05 | 3.4e-04 | 1229 | 81 | 10 | ADAMTS4,CAPN1,CAPNS1,CST3,FAP,FURIN,LAMC1,LRP1,SCUBE3,TIMP2 |
| GO_VESICLE_DOCKING | 3.0e-05 | 3.4e-04 | 1229 | 65 | 9 | EXOC4,EXOC6B,NSF,RAB8B,STX3,STX7,STX8,STXBP2,VPS11 |
| GO_HEPATOCYTE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 3.1e-05 | 3.5e-04 | 1229 | 16 | 5 | ESM1,HGF,MST1,MST1R,SIRT2 |
| GO_REGULATION_OF_EXOSOMAL_SECRETION | 3.1e-05 | 3.5e-04 | 1229 | 16 | 5 | ATP13A2,CHMP2A,PRKN,RAB7A,SDCBP |
| GO_EXOCYTIC_PROCESS | 3.3e-05 | 3.8e-04 | 1229 | 82 | 10 | DMTN,EXOC4,EXOC6B,FCER1G,PSEN1,RAB8B,SNAP23,STX3,STXBP2,VPS11 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | 3.3e-05 | 3.8e-04 | 1229 | 82 | 10 | ADAM17,ADAMTSL2,CD109,FAM89B,GLG1,SKIL,SMAD7,SNX6,TGFBR1,VASN |
| GO_OSTEOCLAST_DIFFERENTIATION | 3.3e-05 | 3.7e-04 | 1229 | 99 | 11 | ATP6AP1,CD109,CD81,CTNNB1,FCER1G,GNAS,LRRK1,NOTCH2,OSTM1,TCTA,TRAF6 |
| GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | 3.4e-05 | 3.8e-04 | 1229 | 219 | 17 | CD276,CD81,CDC42,CYLD,EFNB3,MAP3K8,MDK,NFAT5,RHOA,SIRPA,SIRPB1,STAT5B,TNFRSF14,TNFSF4,TRAF6,VNN1,ZMIZ1 |
| GO_REGULATION_OF_PEPTIDE_SECRETION | 3.4e-05 | 3.8e-04 | 1229 | 511 | 29 | AACS,ANXA4,ATP13A2,CYP51A1,ERP29,EXOC1,FRMD4A,FRMD8,GLUL,HK1,HMGCR,IL17RA,ITPR2,LRP1,MDK,MPC2,NLRP10,PAX8,PRKN,RAB11FIP5,RAB8B,RHBDF1,SERPINB1,SPTBN1,TNFRSF14,TNFSF4,TRAF6,TRPM4,TRPV4 |
| GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 3.5e-05 | 3.9e-04 | 1229 | 264 | 19 | APLP2,APP,CD109,CST3,CSTB,DHCR24,FNIP1,FURIN,HGF,HRG,IGBP1,LRP1,MICAL1,PRDX5,PROS1,SERPINB1,SERPINB6,TIMP2,UBXN1 |
| GO_CEREBRAL_CORTEX_DEVELOPMENT | 3.6e-05 | 4.0e-04 | 1229 | 118 | 12 | CRK,CTNNB1,DAB2IP,FGF13,GSK3B,LRP1,MDK,NCOA1,PSEN1,RHOA,RTN4,SLC38A2 |
| GO_RESPONSE_TO_NUTRIENT | 3.6e-05 | 4.0e-04 | 1229 | 220 | 17 | AACS,ACSL1,AKR1C3,ASS1,BAIAP2,CASTOR2,CASTOR3,EEF2,GNAI2,HMGCR,HMGCS1,HMOX1,MAP1B,NCOA1,NQO1,P2RX6,TRPM4 |
| GO_ORGANELLE_TRANSPORT_ALONG_MICROTUBULE | 3.7e-05 | 4.1e-04 | 1229 | 83 | 10 | ARHGAP21,CDC42,CLN3,COPG1,DYNC1H1,KIF3C,KIFAP3,MAP1B,MAP2,RHOT1 |
| GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 3.7e-05 | 4.2e-04 | 1229 | 540 | 30 | CHMP2A,CTDP1,CTSB,CYLD,DAB2IP,FCER1G,GRAMD4,GRN,HYAL3,IGF2R,LRSAM1,LY96,MAPKAPK2,NLRP10,OPTN,PC,PJA2,RAB7A,RFTN1,RTN4,SIRT2,SKP1,SLAMF6,STAT5B,STING1,TANK,TOP2B,TRAF6,TRIM21,WDFY1 |
| GO_PROTEIN_POLYUBIQUITINATION | 3.7e-05 | 4.1e-04 | 1229 | 312 | 21 | CTNNB1,DYSF,FBXL12,FBXO32,HECTD1,HERC6,LRSAM1,MIB2,NPEPPS,PRKN,RNF14,RNF146,SHARPIN,SKP1,TRAF6,TRIM21,UBE2B,UBE2H,UBE2R2,UBE4B,UBR2 |
| GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 3.7e-05 | 4.1e-04 | 1229 | 157 | 14 | APP,ARNT,CAVIN3,GSK3B,INPP5K,INSR,PINK1,PPP1R3F,PRXL2C,PSEN1,RHOA,SLC2A6,SORBS1,TRPV4 |
| GO_NEURON_APOPTOTIC_PROCESS | 3.8e-05 | 4.2e-04 | 1229 | 243 | 18 | AMBRA1,APP,CDC42,CLN3,CTNNB1,GRN,HMOX1,ILK,ITGA1,LRP1,MDK,NQO1,PCSK9,PINK1,PRKN,PSEN1,RHOA,SNX6 |
| GO_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | 3.8e-05 | 4.2e-04 | 1229 | 52 | 8 | CDC42,CRK,DMTN,KANK1,MDK,MYADM,NEDD9,WASHC2C |
| GO_GLYCOPROTEIN_METABOLIC_PROCESS | 4.0e-05 | 4.4e-04 | 1229 | 412 | 25 | ACAN,ACOT8,B3GNT2,B3GNT9,CHP1,CHPF,CSPG4,CST3,CTNNB1,DCN,FOXL1,GALNT3,GOLGA2,MAN1A2,MAN2A1,MAN2A2,MANBA,OS9,PMM1,PSEN1,RNF103,SOAT1,TMEM165,TMEM59,UST |
| GO_LIPID_OXIDATION | 4.0e-05 | 4.4e-04 | 1229 | 101 | 11 | ACAT1,ACAT2,ACOT8,ACOX1,ADH5,APOD,DECR1,EHHADH,HADHA,HADHB,PHYH |
| GO_CYTOKINETIC_PROCESS | 4.1e-05 | 4.5e-04 | 1229 | 39 | 7 | ANXA11,CHMP1B,CHMP2A,KLHDC8B,RHOA,SNX33,SNX9 |
| GO_MANNOSE_METABOLIC_PROCESS | 4.1e-05 | 4.5e-04 | 1229 | 9 | 4 | HK1,MAN2A1,MAN2A2,PMM1 |
| GO_NEGATIVE_REGULATION_OF_AUTOPHAGY | 4.1e-05 | 4.5e-04 | 1229 | 84 | 10 | CTSA,GOLGA2,HGF,HMOX1,KDM4A,MTM1,PINK1,RUBCN,SIRT2,TSC2 |
| GO_REGULATION_OF_MODIFICATION_OF_POSTSYNAPTIC_STRUCTURE | 4.1e-05 | 4.5e-04 | 1229 | 9 | 4 | BAIAP2,CDC42,CYFIP1,RHOA |
| GO_TISSUE_MIGRATION | 4.1e-05 | 4.5e-04 | 1229 | 363 | 23 | ADAM17,BCAS3,CORO1B,DAB2IP,DCN,EFNA1,FAP,GLUL,GRN,HDAC5,HMOX1,HRG,ITGB1,KANK1,MACF1,NOS3,NR4A1,PRCP,PTPRR,RHOA,RTN4,TGFBR1,WDPCP |
| GO_ISOPRENOID_METABOLIC_PROCESS | 4.2e-05 | 4.6e-04 | 1229 | 139 | 13 | ADH5,AKR1C3,FDFT1,FDPS,HMGCR,HMGCS1,IDI1,LRP1,LSS,PHYH,RETSAT,SCPEP1,SDC2 |
| GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 4.3e-05 | 4.7e-04 | 1229 | 223 | 17 | ACVR1,CTNNA1,CYLD,DAB2IP,DEDD2,GABARAP,GSK3B,HGF,HMOX1,ITGAV,LGALS3,MADD,MOAP1,NOS3,SKIL,TGFBR1,TMBIM1 |
| GO_LATE_ENDOSOME_TO_VACUOLE_TRANSPORT | 4.3e-05 | 4.7e-04 | 1229 | 17 | 5 | CHMP1B,CHMP2A,LEPROT,TMEM50A,TMEM50B |
| GO_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 4.3e-05 | 4.7e-04 | 1229 | 53 | 8 | CDC42,DAB2IP,DUSP3,EPS15,ITGA1,PSEN1,RAB7A,SNX6 |
| GO_ORGANOPHOSPHATE_ESTER_TRANSPORT | 4.3e-05 | 4.6e-04 | 1229 | 120 | 12 | ABCC11,APOC1,ATP10D,ATP11A,ATP9A,CERT1,OSBPL2,PITPNM1,SCARB2,SLC37A1,XKR8,XKR9 |
| GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS | 4.3e-05 | 4.7e-04 | 1229 | 68 | 9 | ABR,FCER1G,ITGAV,LRP1,MFGE8,RAB31,RAPGEF1,SIRPA,SIRPB1 |
| GO_RESPIRATORY_SYSTEM_DEVELOPMENT | 4.3e-05 | 4.6e-04 | 1229 | 201 | 16 | ADAMTSL2,ASS1,CDC42,CHI3L1,CIC,CTNNB1,KLF2,LTBP3,MAN1A2,MAN2A1,MAP2K2,MAPK1,NOS3,RCN3,SAV1,WDPCP |
| GO_ERK1_AND_ERK2_CASCADE | 4.4e-05 | 4.8e-04 | 1229 | 316 | 21 | APP,ATP6AP1,CAVIN3,CHI3L1,DAB2IP,DSTYK,DUSP3,GNAI2,GPNMB,HMGCR,ITGAV,LRP1,MAP2K2,MAPK1,NOTCH2,PRXL2C,PTPRR,RAPGEF1,RRAS,SIRPA,TRPV4 |
| GO_MONOSACCHARIDE_METABOLIC_PROCESS | 4.4e-05 | 4.8e-04 | 1229 | 292 | 20 | APOD,CYB5R3,GAA,GSK3B,HECTD4,HK1,INPP5K,INSR,MAN2A1,MAN2A2,MST1,PC,PGM1,PGM2L1,PMM1,PPP1R3F,PRKN,RBKS,SORBS1,WDTC1 |
| GO_LEUKOCYTE_CHEMOTAXIS | 4.5e-05 | 4.9e-04 | 1229 | 224 | 17 | ADAM17,CXCR4,DYSF,FCER1G,IL17RA,ITGA1,LGALS3,LYST,MDK,MOSPD2,MST1,MTUS1,PIP5K1C,SWAP70,TMEM102,TRPM4,TRPV4 |
| GO_EPITHELIAL_CELL_PROLIFERATION | 4.6e-05 | 4.9e-04 | 1229 | 441 | 26 | ADAM17,ARNT,CD109,CDC42,CTNNB1,DAB2IP,DYSF,FAP,GLUL,GRN,HGF,HMOX1,KDM5B,LAMC1,MAP2K2,MAPK1,MDK,MST1,NOTCH2,NR4A1,PSEN1,RTN4,SAV1,SERPINB1,TGFBR1,TINF2 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | 4.6e-05 | 5.0e-04 | 1229 | 121 | 12 | ADAM17,ADAMTSL2,CD109,DAB2,FAM89B,GLG1,SDCBP,SKIL,SMAD7,SNX6,TGFBR1,VASN |
| GO_RESPONSE_TO_BACTERIUM | 4.7e-05 | 5.0e-04 | 1229 | 711 | 36 | ABR,ADAM17,ADH5,ASS1,BAIAP2,CDK19,DAB2IP,DCN,FCER1G,GBP2,GRN,HDAC5,HERC6,IGHV3-74,LITAF,LY96,LYST,MAPK1,MAPKAPK2,MICA,NLRP10,NOS3,NOTCH2,OPTN,OTUD5,RHOA,SIRPA,SIRT2,SLC17A5,SPON2,STOX2,TNFRSF14,TNFSF4,TRAF6,VIM,WASL |
Num: 5 (Pathways: 831 DK: 13)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (13) | ALPK3, CDC42BPB, CDK15, CDKL5, ICK, NEK10, NEK8, NRBP2, PAK3, PAK6, STK32C, STK36, WNK3 |
| Light Kinase (34) | ABL1, AXL, CKB, DGKA, DGKB, DMPK, EIF2AK4, EPHA1, EPHA5, ERBB2, FGR, IGF1R, IKBKB, IKBKE, LIMK2, LRRK2, MAP2K5, MAP3K11, MAP3K12, MAPK3, MYLK, NPR1, PIK3CB, PKDCC, PRKCD, PRKD1, PRKY, RAF1, ROS1, STK16, STRADA, TIE1, TRIO, ULK2 |
| Non-kinase Count | 1605 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1405 | 187 | ABCA4,ABCD1,ABHD4,ACAD10,ACADL,ACADS,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADGRF5,AGPAT1,AGPAT4,AGT,AJUBA,ALDH3B1,ALG6,ALG9,ALOX15B,AOAH,APOC3,APOE,APOL1,APOL2,APOL4,APPL2,ARF3,ARSA,ASAH1,ASPG,AUH,B3GALT4,B4GALNT2,B4GALT6,BDH2,BMP5,C3,CAV3,CBR4,CCR7,CD36,CEL,CERK,CERS6,CES4A,CETP,CISH,CNR1,CPNE7,CPT2,CYGB,CYP17A1,CYP27B1,CYP2C18,CYP2E1,CYP7B1,DAGLA,DBI,DECR2,DGKA,DGKB,DKK3,DKKL1,DNAJC15,DOLK,DPM3,EBPL,ECHDC2,ECI2,ELOVL3,ELOVL5,ETFB,FGR,GIP,GPAM,GPD1,GPER1,GPX1,GSTA1,GSTM2,HACD1,HACD2,HADH,HPGD,HSD17B1,HSD3B7,HSPG2,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,ITGB8,IVD,LAMTOR1,LDAH,LEPR,LGALS12,LIMA1,LPGAT1,LPIN3,LYPLA2,MAPK3,MGST2,MPPE1,MTMR4,MTTP,NR2F2,OMA1,OPA3,OSBPL5,OSBPL9,PCYT2,PDE3A,PDP2,PEX11A,PEX13,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLD4,PLEKHA1,PLIN1,PLSCR1,PNPLA3,PPARD,PRKCD,PRKD1,PTGDS,RARRES2,RBL2,RDH11,RDH14,REST,RORC,RUFY1,RXRA,SCARF1,SCP2,SERPINA3,SERPINA6,SGPP2,SLC27A2,SLC27A4,SOCS5,SPTSSA,ST3GAL6,ST6GALNAC5,ST6GALNAC6,STAR,STRA6,STS,SULT1A1,SULT1B1,SULT1E1,SUMF1,TBXAS1,THRA,TNFAIP8L3,TRERF1,TTC39B,TTC7A,UGT2B11,VDR,WDR81 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1962 | 205 | AASS,ABCD1,ACAD10,ACADL,ACADS,ACCS,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADA,ADCY6,ADI1,ADO,AGPAT1,AGPAT4,AK1,AK3,ALDH1L1,ALDH3B1,ALOX15B,ANGPT1,AOAH,AP2A1,APOBEC3C,APOBEC3G,APOC3,APOE,APOL1,APOL2,APPL2,ASAH1,ASPG,AUH,B3GLCT,B4GALNT2,B4GALT1,B4GALT6,BAD,BDH2,BGN,BMP5,C3,CBR4,CD36,CEL,CETP,CHST14,CHST9,CKB,CNR1,COQ9,CPT2,CTPS2,CYGB,CYP17A1,CYP27B1,CYP2C18,CYP2E1,CYP7B1,DAGLA,DBI,DBT,DDO,DECR2,DGLUCY,DGUOK,DKK3,DKKL1,DMAC2L,DPYD,DPYS,ECHDC2,ECI2,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD4,ENTPD5,ETFB,FCSK,FMO1,FMO2,FOLH1,FOLR1,GIP,GPAM,GPD1,GPER1,GPT,GPX1,GSTA1,GSTM2,HACD1,HACD2,HADH,HOGA1,HPD,HPGD,HSD3B7,HYAL1,IARS2,IDNK,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,ITIH3,IVD,JMJD8,KAT2B,KMO,KYAT1,LDHD,LEPR,LIMA1,LPGAT1,LPIN3,LRRK2,LYPLA2,MAN2B2,MAPK3,MARC2,MCCC1,MGST2,MME,MYOF,NDST1,NDST4,NEIL1,NME3,NME4,NPR1,NUDT12,NUDT13,NUDT3,OMA1,OSBPL5,OSBPL9,PANK1,PARP9,PDE1A,PDE7B,PDE8B,PDP2,PEX13,PFKFB1,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD4,PNKD,PNPLA3,PPARD,PPP1CB,PRODH,PTGDS,RDH11,RDH14,REST,RORC,RXRA,SARDH,SCARF1,SCP2,SGPP2,SHMT1,SLC25A1,SLC26A1,SLC26A2,SLC27A2,SLC27A4,SLC35D1,SLC52A1,SLC5A3,SLC7A7,ST3GAL3,ST3GAL6,STAR,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,TBXAS1,TCN2,TK2,TKTL1,TP53,TPK1,TRERF1,TTC39B,TXN2,UGT1A6,UGT2B11,VDR,ZBTB7A |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1064 | 143 | ABCA4,ABCD1,ABHD4,ACAD10,ACADL,ACADS,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADGRF5,AGPAT1,AGPAT4,AGT,AJUBA,ALDH3B1,ALG6,ALG9,ALOX15B,AOAH,APOC3,APOE,APPL2,ARF3,ARSA,ASAH1,AUH,B3GALT4,B4GALNT2,B4GALT6,BDH2,C3,CAV3,CBR4,CCR7,CD36,CEL,CERK,CERS6,CETP,CISH,CNR1,CPNE7,CPT2,CYGB,CYP2C18,CYP2E1,DAGLA,DBI,DECR2,DGKA,DGKB,DOLK,DPM3,ECHDC2,ECI2,ELOVL3,ELOVL5,ETFB,FGR,GIP,GPAM,GPD1,GPX1,GSTA1,GSTM2,HACD1,HACD2,HADH,HPGD,HSPG2,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,ITGB8,IVD,LAMTOR1,LPGAT1,LPIN3,LYPLA2,MAPK3,MGST2,MPPE1,MTMR4,OSBPL5,PCYT2,PDP2,PEX13,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLEKHA1,PLSCR1,PNPLA3,PPARD,PRKCD,PRKD1,PTGDS,RARRES2,RDH11,RDH14,RUFY1,SCP2,SGPP2,SLC27A2,SLC27A4,SOCS5,SPTSSA,ST3GAL6,ST6GALNAC5,ST6GALNAC6,STAR,STRA6,STS,SUMF1,TBXAS1,TNFAIP8L3,TTC7A,WDR81 |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1652 | 1984 | 196 | ABL1,ACKR3,ACTN4,ADA,ADARB1,ADGRG1,ADGRL3,AGT,AJUBA,ALOX15B,AMOTL2,ANGPT1,ANGPT2,ANGPT4,APBB2,APCDD1,APOE,APPL2,ARPC5,ARPIN,ASCL1,ATOH8,ATP1A2,ATP1A4,AXL,AZU1,B4GALT1,BCAR1,BMP4,BMP5,CCBE1,CCDC40,CCL28,CCR7,CD99L2,CDC42BPB,CDKL5,CELSR1,CELSR3,CFL1,CHN1,CLDN7,COL18A1,COL1A1,COL1A2,COL3A1,CORO6,CTSH,CXCL12,CXCR5,CYGB,CYP7B1,DACH1,DAG1,DEFB1,DLG5,DNAH3,DOCK1,DOK1,DPP4,EFNA5,EFS,EMB,ENG,EPHA1,EPHA5,ERBB2,F2R,F2RL1,FAT2,FBLN1,FGF7,FGR,FLRT3,FOLR1,FPR1,FSCN1,GATA3,GCSAM,GFRA1,GPER1,GPR183,GPX1,GRB7,HOXA7,HSD3B7,HYAL1,IGF1R,IGFBP5,IGSF8,IL17RC,IL1R1,IL27RA,IL6R,INPP5D,ITGA11,ITGB4,ITGB8,JAGN1,JCHAIN,KANK2,LAMA3,LAMB1,LAMB2,LIMA1,LRRK2,LYPLA2,MAFIP,MAP2K5,MAPK3,MCC,MEGF8,MITF,MMP12,MMP28,MSTN,MYLK,MYO18A,NANOS1,NAV1,NFIB,NOG,NR2F2,NSMF,NTN4,OLR1,OR51E2,PADI2,PAK3,PARP9,PBLD,PDGFC,PDGFD,PDPN,PEX13,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PIP5KL1,PLCB1,PLD1,PLEKHG5,PLXNB1,PLXNB2,PLXNB3,PLXNC1,POU3F3,PPARD,PPIL2,PRKCD,PRKD1,PSG1,PTPRA,PTPRC,PTPRO,PTPRU,RAF1,RAPGEF2,RARRES2,RHOBTB2,RIPOR2,RNASE10,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SLC7A7,SMAD3,SPAG16,SPARC,SPTBN2,STARD13,STAT3,SUN2,SYNE2,TGFBR3,TIE1,TMSB15B,TNFSF12,TNS3,TP53,TPM1,TRIM46,TRIO,TRPM2,TSPAN3,TWIST2,VEGFB,VIL1,VSTM2L,WDR66,WNT5A,ZRANB1 |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 1652 | 1758 | 182 | ABL1,ACKR3,ACTN4,ADA,ADARB1,ADGRG1,ADGRL3,AGT,AJUBA,ALOX15B,AMOTL2,ANGPT1,ANGPT2,ANGPT4,APBB2,APCDD1,APOE,APPL2,ARPC5,ARPIN,ASCL1,ATOH8,ATP1A4,AXL,AZU1,B4GALT1,BCAR1,BMP4,BMP5,CCBE1,CCDC40,CCL28,CCR7,CD99L2,CDC42BPB,CDKL5,CELSR1,CELSR3,CFL1,CLDN7,COL18A1,COL1A1,COL1A2,COL3A1,CORO6,CTSH,CXCL12,CXCR5,CYGB,CYP7B1,DACH1,DAG1,DEFB1,DLG5,DNAH3,DOCK1,DPP4,EFS,ENG,EPHA1,ERBB2,F2R,F2RL1,FAT2,FBLN1,FGF7,FGR,FLRT3,FOLR1,FSCN1,GATA3,GCSAM,GPER1,GPR183,GPX1,GRB7,HOXA7,HSD3B7,HYAL1,IGF1R,IGFBP5,IGSF8,IL17RC,IL1R1,IL27RA,IL6R,INPP5D,ITGA11,ITGB4,ITGB8,JAGN1,JCHAIN,KANK2,LAMA3,LAMB1,LAMB2,LIMA1,LRRK2,MAFIP,MAP2K5,MAPK3,MCC,MEGF8,MITF,MMP12,MMP28,MSTN,MYLK,MYO18A,NANOS1,NAV1,NOG,NR2F2,NSMF,NTN4,OLR1,OR51E2,PADI2,PAK3,PARP9,PBLD,PDGFC,PDGFD,PDPN,PEX13,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PIP5KL1,PLCB1,PLD1,PLEKHG5,PLXNB1,PLXNB2,PLXNB3,PLXNC1,POU3F3,PPARD,PPIL2,PRKCD,PRKD1,PSG1,PTPRC,PTPRO,PTPRU,RAF1,RAPGEF2,RARRES2,RHOBTB2,RIPOR2,RNASE10,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SLC7A7,SMAD3,SPAG16,SPARC,STARD13,STAT3,SUN2,SYNE2,TGFBR3,TIE1,TMSB15B,TNFSF12,TNS3,TP53,TPM1,TRIM46,TRPM2,TSPAN3,TWIST2,VEGFB,VIL1,WDR66,WNT5A,ZRANB1 |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 1425 | 156 | ABL1,ACE2,ACKR3,ACTN1,ACTN4,ADA,ADAM12,ADGRG1,ADGRL3,AGGF1,AJUBA,AKIP1,ANGPT1,ANGPT2,AOC3,AXL,AZU1,B4GALNT2,B4GALT1,BAD,BCAR1,BLOC1S4,BMP4,BMP5,CADM1,CADM3,CCDC80,CCL28,CCN5,CCR7,CD33,CD36,CD4,CD99L2,CDH6,CEL,CELSR1,CELSR3,CLCA2,CLDN7,CNTNAP1,CNTNAP2,CNTNAP4,COL12A1,COL14A1,COL15A1,COL18A1,COL1A1,COL3A1,COL8A2,CTLA4,CTNNA3,CXCL12,CYTIP,DAG1,DLG5,DLL1,DOCK1,DPP4,EFNA5,EFS,EGFL6,EMB,ENG,EPHA1,ERBB2,ERBIN,FAT2,FBLN1,FBLN2,FLOT2,FLRT3,FMN1,GATA3,GLDN,GPAM,GPM6B,HFE,HOXA7,HPSE,HYAL1,INPPL1,ISLR,ITGA11,ITGB4,ITGB8,LAMA3,LAMB1,LAMB2,LAX1,LIMS2,LMLN,LOXL3,LY6D,MAP2K5,MMP12,MSLN,MXRA8,MYL9,NLGN3,NPHP1,NTN4,OLR1,PAK3,PARVB,PCDH15,PCDH9,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PCDHB8,PCDHGA2,PCDHGB6,PCDHGC3,PDLIM1,PDPN,PIK3CB,PIK3R1,PKHD1,PLEKHA7,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPARD,PPP1CB,PRKCD,PTPN22,PTPRC,PTPRO,PTPRU,RAC3,RIPOR2,RNASE10,ROM1,SCARF1,SCARF2,SEMA3E,SERPINF2,SMAD3,SOCS5,SSPO,SVEP1,TENM2,TGFBI,TLN1,TPM1,TRIM29,TRIOBP,UTRN,VSTM2L,VWF,WNT5A,ZBTB16,ZBTB7B |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 1175 | 137 | ABL1,ACKR3,ACTA2,ADAM12,ADGRF5,ADGRG1,AGGF1,AGT,ALPK3,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANK2,ANPEP,APLN,APOE,ARMC4,ASCL1,AXIN2,B4GALT1,BCOR,BMP4,BMP5,C3,CAV3,CCBE1,CCDC40,COL15A1,COL18A1,COL1A1,COL1A2,COL3A1,COL8A2,CPE,CREB3L1,CRIP1,CTSH,DAG1,DAND5,DKK1,DLL1,EDNRA,ENG,EPHA1,ERBB2,EYA1,FHOD3,FLRT3,FOLR1,FOXH1,GATA3,GPER1,GPX1,GTF2I,HEXIM1,HOXA7,HPGD,HPSE,HSPB7,HSPG2,HYAL1,IFT140,IL6R,ITGB8,JMJD8,JPH2,KAT2B,LDB3,LEPR,MAP2K5,MAPK3,MB,MEGF8,MEIS1,MMP2,MOSPD3,MYLK,MYO1E,MYOM1,MYOM3,NDST1,NDUFV2,NEBL,NEK8,NOG,NPR1,NR2F2,OBSL1,OSR1,PDCD4,PDGFD,PDLIM1,PDPN,PIK3CB,PIK3R3,PIN1,PKD2,PLCE1,PPARD,PPP1R13L,PRICKLE4,PRKD1,PTPRB,RAF1,RAMP1,RAPGEF2,REST,RNF213,ROM1,RXRA,SEMA3C,SEMA3E,SEMA4A,SENP2,SERPINF1,SERPINF2,SMAD3,SPARC,STARD13,STAT3,STIM1,STRA6,TAB1,TAL1,TBC1D32,TGFBI,TGFBR3,TIE1,TNFSF12,TNNC1,TP53,TPM1,TRIP11,VEGFB,WNT5A,ZDHHC16 |
| GO_TUBE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 1122 | 130 | ABCA12,ABL1,ACKR3,ADA,ADAM12,ADAMTS2,ADGRF5,ADGRG1,AGGF1,AGT,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANPEP,APLN,APOE,AR,ASCL1,ATOH8,B4GALT1,BMP4,BMP5,C3,CAV3,CCBE1,CCDC40,CELSR1,CFL1,COL15A1,COL18A1,COL3A1,COL8A2,CREB3L1,CRISPLD2,CTSH,CTSZ,DAG1,DLG5,DLL1,EDNRA,EN1,ENG,EPHA1,ERBB2,ESRP2,EYA1,FGF7,FKBP8,FMN1,FOLR1,FOXH1,FZD6,GATA3,GPX1,GTF2I,HOXA7,HPGD,HPSE,HSPG2,HYAL1,IFT140,IGFBP5,IRX3,ITGB4,ITGB8,JMJD8,KLHL3,LEPR,LOXL3,MAP2K5,MAPK3,MEGF8,MEIS1,MME,MMP2,MYLK,MYO1E,NFIA,NFIB,NOG,NPR1,NR2F2,OSR1,PDGFC,PDPN,PIK3CB,PIK3R3,PKD2,PKDCC,PLXNB2,POU3F3,PRKD1,PTPRB,RAMP1,RAPGEF2,RARG,RARRES2,RNF213,RSPO2,SELENON,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SHROOM3,SLC4A2,SMAD3,SPARC,STARD13,STAT3,STIM1,STOX1,STRA6,TAB1,TAL1,TBC1D32,TGFBI,TGFBR3,THRA,TIE1,TMEM107,TNFSF12,TNS3,TP63,VDR,VEGFB,WNT5A,ZNF358 |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 1051 | 125 | ABL1,AGT,ANGPT1,ANGPT2,ANGPT4,AP2A1,APLN,APPL2,AR,ARPC5,ATOH8,ATP6V0A4,AXL,BCAR1,BMP4,BMP5,CAV3,CCBE1,CCND3,CD4,CD7,CDKN1C,CDKN2B,CHMP6,CHN1,COL1A1,COL1A2,COL3A1,COL4A5,CREB3L1,CRIM1,DAND5,DKK1,DKK3,DLL1,DNM1,DOCK1,DOK1,EFEMP1,EFNA5,EID2,EIF4EBP2,ENG,EPHA1,EPHA5,ERBB2,ERBIN,ESRP2,FBXL15,FFAR3,FGF7,FGR,FKBP8,FLRT3,FOLR1,FOXH1,FSTL1,GATA3,GDF5,GFRA1,GPER1,GRB7,HFE,HPGD,IGF1R,IGFBP5,INHA,ITSN1,LNPEP,MAPK3,MEGF8,MMP2,MSTN,MTMR4,MYO1E,MYOF,NCOA5,NDST1,NOG,NPR1,PAK3,PBLD,PCSK6,PDCD4,PDE6G,PDGFC,PDGFD,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PLCB1,PLCE1,PLEKHA1,PMEPA1,POLR2L,PRKCD,PRKD1,PSEN2,PTPN18,PTPRA,PTPRU,RAF1,RAPGEF2,RARRES2,RASL11B,RBPMS,ROS1,SH2D6,SLC2A8,SMAD3,SNX25,SOCS5,STAT3,TAB1,TGFBR3,TIE1,TP53,TRIO,VEGFB,VIL1,WNT5A,ZBTB7A,ZBTB7B |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 0.0e+00 | 1652 | 1107 | 126 | ABL1,ACKR3,ACTN1,ACTN4,ADA,ADARB1,ADGRG1,AGT,AJUBA,ALOX15B,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANK2,APOE,APPL2,ARMC4,ARPIN,ATOH8,ATP1A2,BCAR1,BMP4,BMP5,CAV3,CCBE1,CCDC40,CCL28,CCR7,CD99L2,CLDN7,COL18A1,COL1A1,COL3A1,CTNNA3,CTSH,CXCL12,CYGB,DACH1,DAG1,DEFB1,DLG5,DOCK1,ENG,EPHA1,ERBB2,F2R,F2RL1,FBLN1,FGF7,FGR,GATA3,GCSAM,GPER1,GPR183,GRB7,HOXA7,HYAL1,IGF1R,IGFBP5,IL1R1,IL27RA,IL6R,KCNE3,LAMA3,LAMB1,MAP2K5,MAPK3,MCC,MEGF8,MITF,MMP28,MSTN,MYLK,NOG,NR2F2,NSMF,PADI2,PAK3,PBLD,PDGFC,PDGFD,PDPN,PIK3R1,PIK3R3,PIN1,PIP5KL1,PKHD1,PLCB1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPARD,PRKD1,PTPRC,PTPRO,PTPRU,RAF1,RAPGEF2,RARRES2,RHOBTB2,RIPOR2,RNASE10,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SMAD3,SPARC,STARD13,STAT3,SUN2,SYNE2,TGFBR3,TIE1,TMSB15B,TNNC1,TP53,TPM1,TRIM46,TWIST2,VEGFB,VIL1,WNT5A |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 1721 | 163 | ABL1,ADAMTS7,ADCY6,AGL,AGT,ALDH3A1,APLN,APOE,APPL2,AR,ASCL1,ATP1A2,ATP6V0A4,BACE1,BAD,BCAR1,BMP4,BTG2,CALCR,CALM3,CAV3,CCND3,CCR7,CD36,CD4,CDKN1C,CDKN2B,CLEC3B,COL1A1,COL1A2,COL3A1,COL5A2,CREB3L1,CTSH,CTSS,CXCL12,CYP7B1,DAG1,DAND5,DKK1,DKK3,DNMT3A,EFNA5,EID2,EIF4EBP2,ENG,ERBB2,ESRP2,FAM210B,FBXL15,FFAR3,FGF7,FKBP8,FLRT3,FOLR1,FOXH1,FSTL1,GATA3,GDF5,GIP,GNA14,GNAI1,GNAQ,GPAM,GPD1,GPER1,GSTM2,H3-3A,HADH,HFE,HPGD,HTR2C,HYAL1,IGF1R,IGFBP5,INPPL1,KANK2,KAT2B,KLF15,KLHL22,LAMTOR1,LDOC1,LEPR,LPIN3,LRRK2,LYPD1,MAPK3,MB,MEGF8,MMP2,MSTN,MTMR4,MTSS2,MYD88,NCOA5,NDST1,NOG,NR2F2,NR2F6,NSMF,OR51E2,P2RY11,PADI2,PBLD,PCSK6,PDCD4,PDE3A,PDGFC,PDGFD,PFKFB1,PIAS3,PIK3R1,PIK3R2,PIK3R3,PIN1,PKD2,PLCB1,PMEPA1,POLR2L,PPARD,PRKCD,PTGER2,PTPN22,PTPRA,PTPRU,RAMP1,RAPGEF2,RARG,RARRES2,RASL11B,RECQL5,REST,RORC,RXFP1,RXRA,SELENON,SERPINF1,SESN1,SHMT1,SLC2A8,SMAD3,SNX25,SOCS5,SOX5,SPAAR,SPARC,STAR,STAT3,STK16,TAB1,TGFBR3,THRA,TP53,TP63,TRPM2,TXN2,VDR,VIL1,WFDC1,WNT5A,ZBTB7A,ZBTB7B,ZNF366 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1033 | 121 | AASS,ABCD1,ABHD4,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADA,ADCY6,ADGRF5,AGPAT1,AGPAT4,AJUBA,AK1,AK3,ARF3,BAD,CBR4,CCR7,CETP,CISH,CKB,CPNE7,CTPS2,DBI,DGKA,DGUOK,DMAC2L,DOLK,DPM3,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD4,ENTPD5,FCSK,FGR,GPAM,GPD1,GPER1,GPX1,HACD1,HACD2,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,JMJD8,KMO,LPGAT1,LPIN3,LRRK2,MPPE1,MTMR4,NEIL1,NME3,NME4,NPR1,NUDT12,NUDT13,NUDT3,OSBPL5,PANK1,PARP9,PCYT2,PDE1A,PDE7B,PDE8B,PDP2,PFKFB1,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLD4,PLEKHA1,PLSCR1,PNPLA3,PPARD,PRKCD,PRKD1,RUFY1,SHMT1,SLC25A1,SLC26A1,SLC26A2,SOCS5,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,TK2,TNFAIP8L3,TPK1,TTC7A,WDR81,ZBTB7A |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1117 | 125 | AASS,ABCA7,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADA,ADCY6,AK1,AK3,ALG6,ALG9,ANGPT1,AOAH,AP2A1,APOBEC3C,APOBEC3G,ARSA,ASAH1,B3GALT4,B3GLCT,B3GNT10,B4GALNT2,B4GALT1,B4GALT6,BAD,BGN,CBR4,CCR7,CERK,CHST14,CHST9,CTPS2,DBI,DGUOK,DMAC2L,DOLK,DPM3,DPY19L4,DPYD,DPYS,EDEM3,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD4,ENTPD5,EXT2,EXTL1,FCSK,FUT11,GALNT5,GPAM,GPD1,HACD1,HACD2,HGSNAT,HPSE,HS3ST3B1,HS6ST3,HSPG2,HYAL1,ITGB8,ITIH3,JMJD8,LRRK2,MAN2B2,MGAT4B,MGAT4C,MMP12,MPPE1,MUC15,NDST1,NDST4,NECAB1,NEIL1,NME3,NME4,NPR1,NUDT3,PANK1,PCSK6,PDE1A,PDE7B,PDE8B,PDP2,PFKFB1,PIGB,PIGQ,PIGS,PIGT,PLCB1,POMT1,PPARD,PRKCD,RAMP1,SGSH,SHMT1,SLC25A1,SLC26A1,SLC26A2,SLC35D1,ST3GAL3,ST3GAL6,ST6GALNAC2,ST6GALNAC5,ST6GALNAC6,STAT3,STS,SUCLG2,SULT1A1,SULT1B1,SULT1E1,SUMF1,TK2,TMTC1,TMTC4,TRIP11,VEGFB,XXYLT1,ZBTB7A |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1935 | 172 | ABCA12,ABCA4,ABCD1,ABHD4,ABL1,ACADL,ACKR3,ACOT11,ADA,ADCY6,ADGRF5,AGT,ANK2,APLN,APOC3,APOE,APPL2,ARID4A,ASPSCR1,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,AXL,BAD,BDH2,BMP4,BOK,CA12,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CETP,CIAO3,CKB,CNR1,CPT2,CTSH,CXCL12,CXCR5,CYP27B1,CYP7B1,DLL1,DMPK,DNAJC16,DOCK11,EDNRA,EFNA5,ELOVL3,EPHA5,F2R,F2RL1,FAM210B,FPR1,GATA3,GIP,GPAM,GPER1,GPR183,GPX1,GRM1,GSTM2,GTF2I,HADH,HFE,HMGN3,HSH2D,HTR2C,IGF1R,IGFBP5,INHA,INPP5D,IRX3,JAGN1,JCHAIN,JPH2,KCNN4,KLF15,KLHL10,KLHL3,LAMTOR1,LEPR,LIMA1,LNPEP,LPAR2,LPAR6,LRRK2,MAFB,MAPK3,MB,MSTN,MTTP,NANOS1,NCOA5,NEDD8,NMB,NNT,NPR1,NPR3,OMA1,P4HTM,PARP3,PBLD,PCDH15,PDE6A,PDGFC,PIK3CB,PIK3R1,PIK3R2,PKD2,PKHD1,PLAC8,PLCB1,PLCD4,PLCE1,PLCH2,PNPLA3,POU3F3,PPP1R13L,PTGER2,PTPRC,RAC3,RAF1,RHAG,SCN2B,SCNN1B,SELENON,SERPINA3,SERPINF1,SIDT2,SLC12A9,SLC22A5,SLC24A5,SLC4A2,SLC9A9,SMAD3,STAR,STAT3,STEAP3,STIM1,SV2A,SYNPO,TAL1,TEP1,TGFBR3,THRA,TMEM203,TNKS1BP1,TNS2,TP53,TP63,TPCN2,TRERF1,TRPC4,TRPM2,TTC39B,TTC7A,TXN2,UCP2,USF2,VDR,WNK3,WNT5A,ZBTB7A,ZBTB7B |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 1881 | 169 | ABL1,ACTN4,ADA,ADAMTS7,ADCY6,ADGRG1,AGT,ALOX15B,ANKRD2,AP2A1,APOE,APPL2,AR,ASCL1,ATOH8,AXIN2,AXL,BAD,BHLHB9,BLOC1S5,BMP4,BMP5,BRINP3,CAPN3,CAV3,CD36,CD4,CDKL5,CDKN1C,CETP,CFL1,CHN1,CNR1,COL1A1,COL3A1,COL5A2,CR1,CRP,CSMD3,CTLA4,CTSZ,CUX2,CXCL12,CYP27B1,DAG1,DBNL,DGUOK,DKK1,DKKL1,DLG5,DLL1,DMPK,DOCK1,EFEMP1,EFNA5,EHD2,EID1,EIF2AK4,ENG,ERBB2,EYA1,FAIM,FAM210B,FBLN1,FLOT2,GATA3,GDF5,GLIS1,GPER1,GPR183,H3-3A,H3C6,HECW2,HOPX,HOXA7,HTR2C,IGFBP5,IKBKB,IL6R,INHA,INPP5D,INPP5J,IRX3,ITSN1,KAT2B,KLHL41,LGALS12,LIMS2,LOXL3,LRRK2,MAFB,MCRIP1,MEGF8,MEIS1,MITF,MME,MSTN,MYL9,NCKIPSD,NFAM1,NFE2,NLGN3,NOG,NSMF,OBSL1,OSR1,P4HTM,PAK3,PBLD,PDCD4,PDE3A,PDPN,PHLDB1,PIAS3,PIK3R1,PIN1,PKDCC,PLAAT4,PLCB1,PLPP7,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPARD,PPP1R13L,PRKD1,PRMT6,PRXL2A,PTPRC,PTPRO,RAC3,RAF1,RANBP3L,RAPGEF2,RARG,RARRES2,REST,RIPOR2,RORC,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SMAD3,SOCS5,SOX5,STAR,STAT3,SULT1E1,TAL1,TOB2,TP53,TP63,TRIM46,TRIO,TRIOBP,TWIST2,ULK2,VDR,WASHC5,WNT5A,ZBTB16,ZBTB7B,ZNF219 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 1545 | 149 | ABCD1,ABL1,ADARB1,ADCY6,AGT,AJUBA,AP2A1,APBB2,APOE,ARL13A,ARMC4,ARPC5,ARPIN,B4GALT6,BBOF1,BHLHB9,BLOC1S1,BLOC1S4,BLOC1S5,BMP5,BTG2,CCDC151,CCDC28B,CCDC40,CCDC78,CCR7,CDKL5,CELSR3,CEP70,CFL1,CHN1,CNR1,CNTNAP1,CNTNAP2,CSMD3,CTSZ,CUX2,CXCL12,DAG1,DBNL,DGUOK,DKK1,DLG5,DOCK11,DOK1,EFHD1,EFNA5,EIF2AK4,EMB,EPHA1,EPHA5,ERBB2,F2RL1,FGD3,FGD4,FLRT3,FOLR1,FSCN1,GATA3,GFRA1,GLDN,GPM6B,GRB7,HECW2,ICK,IFT140,IGF1R,INPP5J,INPPL1,ITSN1,KLHL1,KLHL41,LAMB1,LAMB2,LIMA1,LRRK2,LYPLA2,MAFIP,MAPK3,MEGF8,MSTN,MTSS2,MYLK,NCKIPSD,NFIB,NINL,NLGN3,NOG,NPHP1,NSMF,NTN4,NUDCD3,OBSL1,PAK3,PARVB,PDPN,PIK3CB,PIK3R1,PKD2,PKHD1,PLD1,PLEKHA1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKCD,PRKD1,PTPRA,PTPRO,RABL2B,RAC3,RAPGEF2,RIPOR2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SEPTIN11,SERPINF1,SLITRK6,SPAG16,SPG11,SPTBN2,STK36,SYNE2,TBC1D32,TCTN3,TENM2,TMEM107,TMEM80,TPM1,TRIM46,TRIO,TRIOBP,TRIP11,TRPM2,TSKU,TTC30B,TTC39C,ULK2,VAX2,VIL1,VSTM2L,WASHC5,WDR60,WNT5A |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 1869 | 165 | ABCA7,ABL1,ACKR3,ACTN4,ADA,ADGRG1,AGPAT1,AGT,AJUBA,ALOX15B,ANGPT1,APLN,APOE,APOL3,APPL2,AR,ARL6IP5,ASCL1,AXIN2,AXL,BAD,BMP4,BMP5,BOK,C3,CACNB3,CALCR,CALM3,CCBE1,CCR7,CD36,CD4,CDKN1C,CDKN2B,CHN1,CNR1,CNTNAP1,COL1A1,COL3A1,CTSH,CUX2,CXXC5,CYP27B1,DBNL,DKK1,DLG5,DLL1,DOK1,DUSP19,EIF2AK4,ENG,ERBB2,F2R,F2RL1,FBXL15,FGF7,FGR,FKBP8,FPR1,GATA3,GDF5,GIP,GPER1,GPR183,GPX1,GRB7,GRM1,GSTM2,HEXIM1,HFE,HPSE,HSH2D,HTR2C,IGF1R,IGFBP5,IKBKB,IKBKE,IL1R1,IL27RA,IL6R,INHA,ITSN1,JMJD8,JPH2,JRK,KAT2B,KCNN4,KLHL22,KMO,LAMTOR1,LIMS2,LOXL3,LPAR6,LRRK2,MAOA,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MC1R,MIOS,MME,MMP12,MSTN,MYD88,NACC2,NDST1,NEK10,NFAM1,NLGN3,NMB,NPR1,OR51E2,PAK3,PARP9,PDCD4,PDE6G,PDGFC,PDGFD,PIK3CB,PIK3R1,PIK3R2,PIN1,PKD2,PLCB1,PLCE1,PLEKHF1,PLEKHG5,PLXNB1,PPARD,PPM1B,PRKCD,PRKD1,PRR7,PTPN22,PTPRC,RAF1,RAPGEF2,RBPMS,RSPO2,SECTM1,SERPINF2,SH2D6,SMAD3,SPIN1,STAT3,STIMATE,STK36,STOX1,SYT12,TAB1,TGFBR3,TLR1,TMEM9B,TNFAIP8L3,TNFSF12,TP53,TP63,TRIM22,VAMP8,WNT5A,ZBED3,ZBTB7B,ZRANB1 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1164 | 124 | AASS,ABCD1,ACAD10,ACADL,ACADS,ACCS,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADI1,ADO,ALDH1L1,ALOX15B,ANGPT1,AOAH,AP2A1,APOC3,APPL2,ASPG,AUH,B4GALT1,B4GALT6,BDH2,BGN,C3,CBR4,CD36,CEL,CHST14,CHST9,CKB,CNR1,CPT2,CTPS2,CYGB,CYP2C18,CYP2E1,CYP7B1,DAGLA,DBT,DDO,DECR2,DGLUCY,DPYD,DPYS,ECHDC2,ECI2,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD5,ETFB,FMO1,FMO2,FOLH1,FOLR1,GIP,GPAM,GPD1,GPT,GPX1,GSTA1,GSTM2,HACD1,HACD2,HADH,HOGA1,HPD,HPGD,HSD3B7,HYAL1,IARS2,IDNK,ITIH3,IVD,JMJD8,KMO,KYAT1,LDHD,LPGAT1,LPIN3,LYPLA2,MAPK3,MARC2,MCCC1,MGST2,NDST1,NDST4,OSBPL9,PDP2,PEX13,PFKFB1,PNKD,PNPLA3,PPARD,PRODH,PTGDS,SARDH,SCP2,SHMT1,SLC26A1,SLC26A2,SLC27A2,SLC27A4,SLC35D1,SLC7A7,ST3GAL3,ST3GAL6,STAR,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,TBXAS1,TP53,TXN2,UGT1A6,UGT2B11,ZBTB7A |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 1071 | 118 | ABL1,ACTA2,ACTG2,ADARB1,AGT,AP2A1,AR,ATRN,AXIN2,BCOR,BMP1,BMP4,BMP5,CAV3,CCDC40,CELSR1,CELSR3,COL12A1,COL14A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A2,COL8A2,CPE,CRIP1,CTSH,CTSZ,CYP7B1,DAG1,DKK1,DLG5,DLL1,EFEMP1,ENG,ESRP2,EYA1,FGF7,FGR,FMN1,FOLR1,FOXH1,FZD6,GATA3,HOXA4,HOXA7,HOXC13,HSPG2,HYAL1,IFT140,IGFBP5,INPPL1,IRX3,ITGB4,KLHL10,KLHL3,LAMA3,LAMB1,LAMB2,LHX8,LIMS2,LRRK2,MAFB,MAPK3,MEGF8,MEIS1,MGP,MMP2,MYLK,MYOM1,MYOM3,NDST1,NEK8,NFIB,NFIC,NOG,NTN4,OSR1,PDCD4,PDGFC,PKD2,PLEKHA1,POU3F4,PPP1R13L,RARG,RIPOR2,ROM1,RSPO2,RXRA,SEMA3C,SLITRK6,SMAD3,STAT3,STIM1,STOX1,STRA6,TAB1,TGFBR3,THRA,TLE2,TLE5,TNNC1,TP53,TP63,TPM1,TRIOBP,TRIP11,TSHZ1,TSKU,TTC39C,VAX2,VDR,WDR60,WDR72,WNT5A,ZIC1,ZNF22 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1825 | 162 | ABCA7,ABL1,ACADL,ACE2,ADA,ADAM12,ADGRL3,AGGF1,AGPAT1,AGT,ALOX15B,ANGPT1,ANGPT2,ANGPT4,AP2A1,APLN,APOE,APPL2,AR,ASCL1,ATOH8,AXIN2,AXL,AZU1,BAD,BCAR1,BHLHB9,BMP1,BMP4,BMP5,BRINP3,C3,CACNB3,CADM1,CCBE1,CCR7,CD36,CD4,CDKL5,CNR1,COL1A1,CPT2,CTSH,CUX2,CXCL12,CYP27B1,DAG1,DBNL,DKK1,DLG5,DLL1,DOCK1,EFNA5,ELOVL3,ENG,EPHA1,F2R,F2RL1,FAIM,FAM210B,FFAR3,FGF7,FGR,FLRT3,GATA3,GDF5,GPAM,GPER1,GPM6B,HADH,HPSE,HYAL1,IGF1R,IL17RC,IL1R1,IL27RA,IL6R,INHA,INPP5D,IRX3,ITGB8,ITSN1,JMJD8,LEPR,LRRC24,LRRK2,MAPK3,MAVS,MEGF8,MME,MMP12,MYD88,NCKIPSD,NFAM1,NLGN3,NLRX1,NOG,NPR1,NSMF,OBSL1,OMA1,OR51E2,ORM1,OSR1,PAK3,PDE3A,PDGFC,PDGFD,PDPN,PHLDB1,PIK3R1,PIN1,PKDCC,PLAAT4,PLAC8,PLCB1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,POLR2L,PRKD1,PTGER2,PTPN22,PTPRC,RAPGEF2,REST,SCARF1,SEMA3C,SEMA4A,SERPINF1,SERPINF2,SLC1A1,SLC22A5,SLITRK6,SMAD3,SOCS5,SOX5,SPARC,STAR,STAT3,STIM1,STOX1,TAL1,TGFBR3,THRA,TIE1,TLR1,TNFSF12,TOB2,TP63,TPM1,UCP2,VAMP8,VDR,VEGFB,VIL1,WASHC5,WNT5A,ZBTB16,ZBTB7B,ZNF219 |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 766 | 97 | ABL1,ABRACL,ACTN1,ACTN4,ACTR3B,AMOTL2,ANK2,ARHGEF17,ARPC5,ARPIN,ATP1A2,BCAR1,CAPN3,CASQ1,CAV3,CCR7,CDC42BPB,CELSR1,CFL1,CNN2,CORO6,CORO7,CTNNA3,CXCL12,DBNL,EFNA5,EFS,EHD2,EPHA1,EPHA5,F2RL1,FGD3,FGD4,FGF7,FHOD1,FHOD3,FMN1,FRMD6,FSCN1,GMFB,GPM6B,IKBKB,INF2,INPPL1,IQSEC2,KCNE3,KCNE4,KCNJ3,KLHL1,KLHL41,LDB3,LIMA1,LIMK2,LMOD1,MRAS,MSRB1,MSRB2,MYO18A,MYO1E,MYOM1,MYOM3,NAA80,NEBL,NPHP1,OBSL1,PAK3,PARVB,PDLIM1,PDPN,PIK3R1,PRICKLE4,PRKCD,RAC3,RHOBTB2,RTKN,SCN1A,SCN2B,SEMA3E,SERPINF2,SHROOM3,SHROOM4,SMAD3,SPTBN2,SUN2,SYNE2,SYNPO,TLN1,TMOD1,TMSB15B,TNNC1,TNNI2,TPM1,TPM4,TRIOBP,TRPM2,VIL1,VILL |
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 1625 | 149 | ABL1,ADARB1,ADCY6,ADGRG1,ADGRL3,AGT,AP2A1,APBB2,APCDD1,APOE,APPL2,ASCL1,AXL,AZU1,B4GALT6,BHLHB9,BLOC1S1,BLOC1S4,BLOC1S5,BMP4,BMP5,BOK,BRINP3,BTG2,C3,C8orf37,CDKL5,CDKN1C,CELSR1,CELSR3,CFL1,CHN1,CNR1,CNTNAP1,CNTNAP2,COL3A1,CSMD3,CTSZ,CUX2,CXCL12,DAG1,DAGLA,DBNL,DGUOK,DKK1,DLG5,DLL1,DNMT3A,DOK1,EFHD1,EFNA5,EIF2AK4,EMB,EN1,EPHA1,EPHA5,ERBB2,EYA1,FAIM,FLRT3,FOLR1,GATA3,GDF5,GFRA1,GLDN,GPER1,GPM6B,GPR183,GRB7,HECW2,IFT140,INPP5J,IRX3,ITSN1,KLF15,KLHL1,LAMB1,LAMB2,LEPR,LHX8,LRRK2,LYPLA2,MAPK3,MEGF8,MEIS1,MME,MXRA8,NANOS1,NAV1,NAV2,NCKIPSD,NFIB,NLGN3,NOG,NR2F2,NR2F6,NRBP2,NSMF,NTN4,OBSL1,PAK3,PEX13,PIGT,PIK3CB,PIK3R1,PIN1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRA,PTPRO,RAC3,RAPGEF2,REST,RIPOR2,ROM1,RSPO2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SLITRK6,SOX5,SPG11,SPTBN2,STAR,STAT3,SUN2,SYNE2,TAL1,TENM2,TMC1,TP53,TRIM46,TRIO,TRIOBP,TRIP11,TRPC4,TSKU,ULK2,VAX2,VSTM2L,WASHC5,WNT5A |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 1335 | 132 | ABL1,ACTN1,ACTN4,ACTR1B,ACTR3B,AJUBA,AMOTL2,ANK2,APOE,ARHGEF17,ARMC4,ARPC5,ARPIN,BCAR1,CAPN3,CASQ1,CAV3,CCDC151,CCDC40,CCDC69,CCDC78,CCR7,CDC42BPB,CELSR1,CEP70,CFL1,CNN2,CNTNAP1,CORO6,CORO7,CUL9,CXCL12,DAG1,DBNL,EFNA5,EFS,EHD2,EML3,EPHA1,EPHA5,ERBIN,EVPLL,F2RL1,FGD3,FGD4,FGF7,FHOD1,FHOD3,FMN1,FRMD6,FSCN1,GMFB,GNAI1,GPM6B,HOOK2,IKBKB,INF2,INPP5J,INPPL1,IQSEC2,KAT2B,KLHL1,KLHL41,KRT14,KRT5,LDB3,LIMA1,LIMK2,LMOD1,MAP7D2,MAPK3,MRAS,MSRB1,MSRB2,MYO18A,MYOM1,MYOM3,NAA80,NAV1,NCKIPSD,NEBL,NINL,NPHP1,OBSL1,PAK3,PAK6,PARP3,PARVB,PDLIM1,PHLDB1,PIK3R1,PKD2,PKHD1,PLCE1,PLXNB1,PPL,PRICKLE4,PRKCD,PTPA,RAC3,RAF1,RASSF7,RHOBTB2,RTKN,SEMA3E,SERPINF2,SHROOM3,SHROOM4,SMAD3,SPAG16,SPTBN2,SUN2,SYNE2,SYNPO,TCHH,TLN1,TMOD1,TMSB15B,TPM1,TPM4,TRIM37,TRIM46,TRIOBP,TRPM2,TUBA3D,TUBA3E,UBXN2B,VIL1,VILL,WASHC5,ZMYM3,ZRANB1 |
| GO_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 1692 | 152 | ABCA12,ABCA4,ABCA7,ABCC3,ABCD1,ABL1,ACE2,ACTN4,ADA,AGT,ANK2,ANO2,ANO8,APOC3,APOE,APOL1,ARL6IP5,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,ATP8B4,BEST2,BEST4,CA12,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CD33,CD36,CD4,CETP,CLCA2,CLCNKA,CLIC3,CNGB3,CNR1,CPT2,CTSS,CXCL12,CYP27B1,DMAC2L,DMPK,EFHB,EMB,F2R,FOLR1,FXYD3,GPER1,GPM6B,GRAMD2A,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,KLHL3,KMO,MTTP,MYLK,NALCN,NIPAL2,NLGN3,NMB,NNT,OSBPL5,OSR1,PDPN,PDZK1,PITPNM2,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PLSCR1,PLSCR4,PPARD,PRKCD,PSEN2,PTPRC,RAF1,RAMP1,RHAG,ROS1,RXRA,SCN1A,SCN2B,SCNN1B,SCP2,SELENON,SLC12A9,SLC13A4,SLC15A2,SLC16A14,SLC16A7,SLC1A1,SLC20A2,SLC22A5,SLC24A5,SLC25A1,SLC26A1,SLC26A2,SLC27A2,SLC27A4,SLC2A14,SLC2A8,SLC35D1,SLC37A2,SLC38A10,SLC41A3,SLC4A2,SLC52A1,SLC5A2,SLC5A3,SLC7A7,SLC9A9,SLCO1B1,SLCO2A1,SLCO6A1,STAC2,STEAP3,STIM1,STIMATE,STRA6,SV2A,SYT12,TCN2,TMC1,TMEM63A,TNFAIP8L3,TPCN2,TRPC4,TRPM2,UCP2,UTRN,VAMP8,VDR,WNK3 |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 1177 | 122 | ABL1,ACKR3,ACTN1,ADA,ADAM12,ADGRG1,AGGF1,AGT,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANK2,ANPEP,APLN,AR,ATOH8,AXIN2,B4GALT1,BMP4,BMP5,C3,CAPN3,CASQ1,CAV3,CCBE1,CD36,CELSR1,CFL1,CNTNAP1,COL12A1,COL15A1,COL18A1,COL1A1,COL5A2,COL8A2,CREB3L1,CTSH,DAG1,DKK1,DLL1,EDNRA,EHD2,ENG,EPHA1,ERBB2,EXT2,EYA1,FHOD3,FMN1,FOLR1,FOXH1,FZD6,GATA3,GPX1,GTF2I,HOPX,HOXA7,HPSE,HSPG2,HYAL1,IRX3,ITGB4,ITGB8,JMJD8,KLHL41,LAMA3,LAMB1,LDB3,LEPR,LMOD1,MAFB,MAP2K5,MAPK3,MEIS1,MMP2,MYOF,MYOM1,MYOM3,NEBL,NFIB,NOG,NPR1,OBSL1,OSR1,PDPN,PHLDB1,PIK3CB,PIK3R3,PLXNB2,PRKD1,PTPN18,PTPRB,RAMP1,RARG,RIPOR2,RNF213,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SHROOM3,SMAD3,SPARC,STARD13,STAT3,STIM1,STRA6,TAL1,TBX18,TGFBI,TGFBR3,TIE1,TMOD1,TNFSF12,TP53,TP63,TPM1,VEGFB,WDR72,WNT5A,ZNF219 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1652 | 1863 | 161 | ABCA7,ABL1,ACKR3,ACTN4,ADA,ADGRG1,AGT,AJUBA,AKAP1,AKIP1,ANGPT1,ANKRD2,APOC3,APOE,APOL3,AR,ARHGEF17,ARHGEF25,ARL6IP5,AXL,BAD,BMP4,BMP5,BOK,CALCR,CALM3,CAPN3,CAV3,CCR7,CD36,CD4,CHD4,CHN1,COL3A1,CREB3L1,CXCL12,CXXC5,DAG1,DBNL,DKK1,DLG5,DUSP19,EFHB,ENG,ENTPD5,ERBB2,ERBIN,F2R,F2RL1,FBLN1,FBXO9,FGD3,FGD4,FGF7,FGR,FPR1,GATA3,GDF5,GIP,GNAI1,GPER1,GPR183,GPX1,GRM1,GSTM2,HEXIM1,HPSE,HTR2C,IGF1R,IGFBP5,IKBKB,IKBKE,INHA,IQSEC2,ITSN1,JMJD8,JPH2,KANK2,KLHL22,LAMTOR1,LAX1,LPAR6,LRRK2,LZTR1,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MC1R,MECOM,MGRN1,MIOS,MOB3B,MSTN,MYD88,NACC2,NDST1,NEK10,NEK8,NLRX1,NPR1,OR51E2,PAK3,PDCD4,PDE3A,PDE6G,PDGFC,PDGFD,PHLPP1,PIK3CB,PIK3R1,PIK3R2,PIN1,PIP4K2B,PKD2,PKHD1,PLCB1,PLCE1,PLEKHA1,PLEKHF1,PLEKHG5,PLEKHG6,PLXNB1,PPARD,PPM1B,PPP1R13L,PRKCD,PRKD1,PRMT6,PSCA,PTPN22,PTPRC,RAC3,RAF1,RAPGEF2,RCAN1,RCAN3,RHOBTB2,RIPOR2,RNF152,ROS1,SECTM1,SELENON,SERPINF2,SESN1,SPAAR,STARD13,STIMATE,STOX1,STYX,TAB1,TMBIM4,TMEM9B,TNFAIP8L3,TP53,TP63,TRIM22,TRIM59,TRIO,WNT5A |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 1454 | 137 | ABL1,ADAMTS7,ADCY6,AGT,APLN,APPL2,AR,ATP1A2,ATP6V0A4,BACE1,BCAR1,BMP4,CAV3,CCND3,CD36,CDKN1C,CDKN2B,CLEC3B,COL1A1,COL1A2,COL3A1,COL5A2,CREB3L1,CTSH,CTSS,CYP7B1,DAND5,DKK1,DKK3,DNMT3A,EFNA5,EID2,EIF4EBP2,ENG,ERBB2,ESRP2,FAM210B,FBXL15,FFAR3,FGF7,FKBP8,FLRT3,FOLR1,FOXH1,FSTL1,GATA3,GDF5,GNA14,GNAQ,GPAM,GPD1,GPER1,GSTM2,HFE,HPGD,HTR2C,HYAL1,IGF1R,IGFBP5,KANK2,KAT2B,KLF15,KLHL22,LAMTOR1,LDOC1,LEPR,LPIN3,LRRK2,LYPD1,MAPK3,MEGF8,MMP2,MSTN,MTMR4,MTSS2,NCOA5,NDST1,NOG,NR2F2,NR2F6,NSMF,OR51E2,P2RY11,PADI2,PBLD,PCSK6,PDCD4,PDE3A,PDGFC,PDGFD,PIK3R1,PIK3R2,PIK3R3,PIN1,PKD2,PLCB1,PMEPA1,POLR2L,PPARD,PRKCD,PTGER2,PTPN22,PTPRA,RAMP1,RAPGEF2,RARG,RARRES2,RASL11B,RECQL5,REST,RORC,RXFP1,RXRA,SELENON,SERPINF1,SESN1,SHMT1,SLC2A8,SMAD3,SNX25,SOX5,SPAAR,STAR,STAT3,STK16,TAB1,TGFBR3,THRA,TP53,TP63,TRPM2,VDR,VIL1,WNT5A,ZBTB7A,ZBTB7B,ZNF366 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1823 | 157 | ABCA7,ABCD1,ABL1,ACKR3,ADARB1,ADCY6,ADGRF5,AGT,AJUBA,ANGPT1,ANGPT4,APLN,APOE,AR,ARL6IP5,AXIN2,AZU1,BAD,BMP4,BMP5,C3,CABIN1,CALCR,CALM3,CAV3,CCND3,CCR7,CD33,CD36,CD4,CDKN1C,CDKN2B,CELSR3,CHMP6,CISH,DAG1,DBNL,DKK1,DMPK,DNAJC15,DOCK3,DUSP19,EFNA5,EIF2AK4,ENG,ENTPD5,EPHA1,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGF7,FGR,FKBP8,FPR1,GDF5,GMFB,GNAQ,GPD1,GPER1,GPR183,GPRC5C,GRM1,HEXIM1,HEXIM2,HFE,HTR2C,IGF1R,IKBKB,IL27RA,IL6R,INHA,INPP5J,ITSN1,JMJD8,KAT2B,LAMTOR1,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MECOM,MLLT1,MSTN,MTCP1,MTMR4,NDST1,NEK10,NNT,NOG,NR2F2,NSMF,PAK3,PAK6,PARP9,PBLD,PCIF1,PDCD4,PDE6G,PDGFC,PDGFD,PDP2,PFKFB1,PHLPP1,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PIP5KL1,PKD2,PKHD1,PLCB1,PLCE1,PLXNB2,PMEPA1,PPP1R35,PPP6R2,PRKCD,PRKD1,PSCA,PTPA,PTPN22,PTPRC,RAF1,RAPGEF2,RARRES2,RBL2,RBPMS,RCAN1,RCAN3,ROS1,SENP2,SERPINF2,SMAD3,SNX25,SOCS5,STAT3,STOX1,STRADA,STYX,TAB1,TAL1,TNFAIP8L3,TNKS1BP1,TP53,TSPYL2,VEGFB,WDR81,WNK3,WNT5A,ZBED3,ZBTB7A |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 1141 | 117 | ABL1,ACTN1,ACTN4,ADARB1,AKIP1,ANK2,APBB2,APOE,AR,ARPIN,AXL,B4GALT6,BHLHB9,C8orf37,CAPN3,CASQ1,CAV3,CDH6,CDKL5,CELSR3,CFL1,CHN1,CNTNAP1,CNTNAP2,COL12A1,COL14A1,COL18A1,CUX2,CXCL12,DAG1,DBNL,DKK1,DOCK1,DOK1,EFNA5,EIF2AK4,EMB,EPHA1,EPHA5,ERBB2,FBLN1,FGD3,FGD4,FGR,FHOD3,FLRT3,FRMD6,GATA3,GFRA1,GRB7,HECW2,KLHL10,KLHL41,LAMB1,LAMB2,LDB3,LIMS2,LMOD1,LRRK2,LYPLA2,MAPK3,MEGF8,MYOM1,MYOM3,NEBL,NFIB,NLGN3,NOG,NSMF,NTN4,NUBPL,OBSL1,OPA3,PAK3,PALM2AKAP2,PALMD,PARVB,PDPN,PHLDB1,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRA,PTPRO,RAC3,RAPGEF2,RHOBTB2,RIPOR2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SHROOM3,SIDT2,SLITRK6,SPARC,SPG11,SPTBN2,SSH3,TAL1,TMOD1,TPM1,TRIM46,TRIO,TRIOBP,TSKU,ULK2,VAX2,VDR,VIL1,VSTM2L,WNT5A,ZMYM3,ZRANB1 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1652 | 1994 | 164 | ABCA7,ABL1,ACKR3,ADARB1,ADCY6,AGT,AJUBA,ALPK3,ANGPT1,ANGPT4,APOE,AR,ARL6IP5,AXIN2,AXL,AZU1,BMP4,BMP5,C3,CALCR,CALM3,CAV3,CCND3,CCR7,CD36,CD4,CDC42BPB,CDK15,CDKL5,CDKN1C,CDKN2B,CELSR3,CFL1,CHMP6,CTSH,DAG1,DBNL,DGUOK,DKK1,DMPK,DOCK3,DUSP19,EFEMP1,EFNA5,EIF2AK4,ENG,EPHA1,EPHA5,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGF7,FGR,FKBP8,FPR1,GDF5,GFRA1,GMFB,GNAQ,GPER1,GPR183,GPRC5C,GRM1,GTF2H5,HEXIM1,HEXIM2,HFE,HTR2C,ICK,IGF1R,IKBKB,IKBKE,IL27RA,IL6R,INHA,INPP5J,IP6K3,KAT2B,KBTBD7,LAMTOR1,LAX1,LIMK2,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MECOM,MLLT1,MSTN,MTCP1,MYLK,NDST1,NEK10,NEK8,NNT,NOG,NPR1,NR2F2,NRBP2,PAK3,PAK6,PARP9,PBLD,PDCD4,PDE6G,PDGFC,PDGFD,PEAK3,PHLPP1,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PIP5KL1,PKD2,PKDCC,PKHD1,PLCB1,PLCE1,PLXNB2,PMEPA1,PRKCD,PRKD1,PRKY,PSCA,PTPN22,PTPRA,PTPRC,RAF1,RAPGEF2,RARRES2,RBPMS,ROS1,SENP2,SERPINF2,SNX25,SOCS5,SPTBN2,STAT3,STK16,STK32C,STK36,STOX1,STRADA,STYX,TAB1,TAL1,TGFBR3,TIE1,TNFAIP8L3,TNKS1BP1,TP53,TRIO,TSPYL2,ULK2,VEGFB,WNK3,WNT5A,ZBED3 |
| GO_CHEMICAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 1207 | 120 | ABCA12,ABCD1,ABHD4,ABL1,ACKR3,ADCY6,ADGRF5,AGT,ANK2,APOC3,APOE,APPL2,ASPSCR1,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BAD,BDH2,BOK,CA12,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CETP,CIAO3,CKB,CNR1,CTSH,CXCL12,CXCR5,CYP27B1,CYP7B1,DMPK,EDNRA,EFNA5,EPHA5,F2R,F2RL1,FPR1,GIP,GPAM,GPER1,GRM1,GSTM2,GTF2I,HFE,HMGN3,HSH2D,HTR2C,IGF1R,IGFBP5,JAGN1,JPH2,KLF15,KLHL3,LAMTOR1,LEPR,LIMA1,LPAR2,LPAR6,LRRK2,MAPK3,MTTP,NCOA5,NEDD8,NMB,NNT,NPR1,PDE6A,PIK3CB,PIK3R1,PIK3R2,PKD2,PKHD1,PLCB1,PLCD4,PLCE1,PLCH2,PNPLA3,POU3F3,PTGER2,PTPRC,RAF1,RHAG,SCN2B,SCNN1B,SELENON,SERPINF1,SIDT2,SLC12A9,SLC24A5,SLC4A2,SLC9A9,SMAD3,STAR,STAT3,STEAP3,STIM1,SV2A,SYNPO,TMEM203,TP53,TP63,TPCN2,TRPC4,TRPM2,TTC39B,TTC7A,USF2,VDR,WNK3,WNT5A |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1652 | 1625 | 143 | ABCA7,ABCD1,ABL1,ACKR3,ADARB1,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,APLN,APOE,AR,ARL6IP5,AXIN2,AZU1,BAD,BMP4,BMP5,C3,CALCR,CALM3,CAV3,CCND3,CCR7,CD36,CD4,CDKN1C,CDKN2B,CELSR3,CHMP6,CISH,DAG1,DBNL,DKK1,DNAJC15,DOCK3,DUSP19,EFNA5,EIF2AK4,ENG,ENTPD5,EPHA1,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGF7,FGR,FKBP8,FPR1,GDF5,GMFB,GNAQ,GPD1,GPER1,GPR183,GPRC5C,GRM1,HEXIM1,HEXIM2,HFE,HTR2C,IGF1R,IKBKB,IL27RA,IL6R,INHA,INPP5J,ITSN1,JMJD8,KAT2B,LAMTOR1,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MECOM,MLLT1,MSTN,MTCP1,NDST1,NEK10,NNT,NOG,NR2F2,PAK3,PAK6,PARP9,PBLD,PDCD4,PDE6G,PDGFC,PDGFD,PFKFB1,PHLPP1,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PIP5KL1,PKD2,PKHD1,PLCB1,PLCE1,PLXNB2,PMEPA1,PRKCD,PRKD1,PSCA,PTPN22,PTPRC,RAF1,RAPGEF2,RARRES2,RBL2,RBPMS,ROS1,SENP2,SERPINF2,SNX25,SOCS5,STAT3,STOX1,STRADA,STYX,TAB1,TAL1,TNFAIP8L3,TNKS1BP1,TP53,TSPYL2,VEGFB,WDR81,WNK3,WNT5A,ZBED3,ZBTB7A |
| GO_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 1296 | 124 | ABCA12,ABL1,ACTA2,ADAMTSL4,AGT,AJUBA,ALOX15B,AP2A1,APCDD1,AR,ARID4A,ASAH1,ASCL1,ATOH8,AXIN2,B4GALT1,BAD,BDH2,BMP4,BMP5,CAV3,CCDC40,CCDC78,CDKN1C,CELSR1,CELSR3,CFL1,COL18A1,CTSH,CTSZ,CYP27B1,CYP7B1,DAG1,DKK1,DLG5,DLL1,EDNRA,EHF,EN1,ENG,ESRP2,EYA1,F2RL1,FGF7,FKBP8,FLRT3,FMN1,FOLR1,FOXH1,FRMD6,FZD6,GATA3,GPX1,GSTA1,GSTA2,HOXA7,HOXC13,HPSE,IFT140,IGFBP5,IKBKB,IRX3,KANK2,KLF15,KLHL3,KRT14,KRT5,KRT7,KRT81,KRTAP1-5,LAMA3,LAMB2,LOXL3,MEGF8,MMP12,MYO1E,NFIB,NOG,NR2F2,NTN4,OSR1,PCSK6,PDPN,PKD2,PLAAT4,PLXNB2,POU3F3,PPL,PTPRO,PYGO2,RAPGEF2,RARG,RIPOR2,ROS1,RSPO2,RXRA,SEMA3C,SEMA3E,SHROOM3,SIDT2,SLITRK6,SMAD3,SPINK9,STARD13,STOX1,STRA6,SULT1B1,TAGLN2,TBC1D32,TBX18,TCHH,TGM1,THRA,TMC1,TMEM107,TMOD1,TP53,TP63,TRIOBP,VDR,VIL1,WNT5A,ZDHHC21,ZNF358 |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 1894 | 157 | ABCA12,ABCA7,ABL1,ACE2,ACTN4,ADA,AGT,ALOX15B,ANGPT1,ANK2,ANXA13,AP2A1,APLN,APOC3,APOE,APPL2,ARL6IP5,ASPSCR1,ATP1A2,AXL,AZU1,BACE1,BAD,BMP4,BOK,C3,C4A,C4B,CACNB3,CACNG8,CADM1,CADPS2,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CD33,CD36,CD4,CETP,CLCNKA,CLIC3,CNR1,CRP,CTSS,CXCL12,DKK1,DLL1,DMPK,DNM1,DPP4,EDNRA,EFHB,EFNA5,EHD2,EPHA5,ERBB2,F2R,F2RL1,FFAR3,FGR,FXYD3,GAS1,GATA3,GIP,GPAM,GPER1,GPM6B,GRAMD2A,GSTM2,HADH,HECW2,HFE,HMGN3,HSPA1L,HTR2C,IL17RC,IL27RA,INHA,ITSN1,JAGN1,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNN4,KLF15,KMO,LAMTOR1,LRRK2,MAPK3,MAVS,MMP12,MYLK,MYO18A,MYOM1,NALCN,NLGN3,NMB,NPR1,OR51E2,ORM1,OSR1,PDZK1,PIK3CB,PIK3R1,PIK3R2,PKD2,PKDCC,PLD1,PNKD,PPARD,PRKCD,PRKD1,PSEN2,PTPN22,PTPRC,RAB11FIP3,REST,ROS1,RUFY1,SCN1A,SCN2B,SCP2,SEC16A,SELENON,SEPTIN8,SIDT2,SMAD3,SNCAIP,SSC5D,STAC2,STIM1,STIMATE,SV2A,SYT12,TBC1D5,TLR1,TMC1,TNNC1,TP53,TP63,TPCN2,TRIM46,TTC39B,UTRN,VAMP8,VPS28,VPS41,WNK3,WNT5A,ZIC1 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1652 | 1748 | 149 | ABL1,ACKR3,ACTN1,ACTN4,ADA,ADAMTSL4,AGT,ANGPT1,ANGPT4,ANKRD2,APBB2,APOE,AR,AREL1,ARHGEF17,ARL6IP5,ASCL1,AXIN2,AXL,AZU1,B4GALT1,BACE1,BAD,BCAR1,BEX3,BHLHB9,BMP4,BMP5,BOK,BTG2,CAAP1,CALCR,CAPN3,CCN5,CCR7,CD36,CFL1,CLDN7,CNR1,COL18A1,CREB3L1,CTLA4,CTSH,CTSZ,CXCL12,DKK1,DKKL1,DLG5,DLL1,DNMT3A,EIF2AK4,EN1,ERCC5,EYA1,F2R,FAIM,FGD3,FGD4,FKBP8,GAS1,GATA3,GDF5,GPAM,GPER1,GPX1,HPGD,HSH2D,IGF1R,IKBKB,INHA,INPP5D,ITSN1,KANK2,KMO,LANCL1,LIMS2,LRRK2,MAP2K5,MAP3K11,MAP3K12,MECOM,MITF,MSTN,MYD88,MYO18A,NACC2,NNT,NOG,NRBP2,NSMF,OMA1,OSR1,PAK3,PANO1,PDCD4,PDE1A,PDE3A,PDPN,PHLPP1,PIK3CB,PIK3R1,PIN1,PIP5KL1,PKHD1,PLAC8,PLEKHF1,PLEKHG5,POU3F3,POU3F4,PPARD,PRKCD,PRKD1,PRODH,PRR7,PSEN2,PTPA,PTPRC,RABGGTA,RAF1,RAPGEF2,RARG,REST,RTKN,SERPINF1,SMAD3,ST20,STAR,STAT3,STEAP3,TCTN3,THRA,TIAF1,TLE5,TMBIM4,TNFAIP8L3,TNFRSF10C,TNFRSF25,TNFSF12,TP53,TP63,TRIO,TWIST2,VDR,VIL1,VSTM2L,WNK3,WNT5A,ZBTB16,ZBTB7A |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 1703 | 146 | ABCD1,ABL1,ACKR3,ADA,AGT,AJUBA,ANGPT1,ANGPT2,APCDD1,APLN,APOE,APPL2,AR,ARL6IP5,AXIN2,BACE1,BMP4,BMP5,BOK,CAAP1,CACNB3,CALM3,CAV3,CHMP6,CISH,CNR1,COL3A1,CR1,CREB3L1,CTLA4,CUEDC2,CXCL12,CYP7B1,DAG1,DAND5,DKK1,DKK3,DKKL1,DLG5,DLL1,DNM1,DUSP19,EID2,ERBB2,ERBIN,EYA1,F2RL1,FAIM,FBLN1,FOXH1,FZD6,GATA3,GPER1,GPX1,GSTM2,HFE,IGF1R,IGFBP5,IL27RA,INPP5D,INVS,JAGN1,KANK2,LAX1,LOXL3,LRRK2,LZTR1,MAP2K5,MCC,MECOM,MEGF8,MGRN1,MLIP,MMP12,MMP28,MSTN,MTMR4,NCOA5,NLGN3,NLRX1,NOG,NOTUM,NUDT16L1,OSR1,PADI2,PARP3,PBLD,PDCD4,PDE3A,PHLPP1,PIK3R2,PIN1,PKD2,PKHD1,PLEKHA1,PMEPA1,PPARD,PPM1B,PRKCD,PSCA,PTPN18,PTPN22,PTPRC,PTPRO,PTPRU,PVRIG,RAF1,RASL11B,RBMS3,RCAN1,RECQL5,REST,RGS7BP,RIPOR2,RNF152,RNF213,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SESN1,SMAD3,SNX25,SOCS5,SPAAR,TAX1BP3,TBX18,TGFBR3,TLE2,TLE5,TP53,TP63,TRABD2A,TRABD2B,TRIM59,TSKU,TSPAN8,VPS13C,WFDC1,WNT5A,ZBTB7A,ZBTB7B,ZNF366 |
| GO_TUBE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 928 | 101 | ABL1,ACKR3,ADAM12,ADGRF5,ADGRG1,AGGF1,AGT,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANPEP,APLN,APOE,AR,ATOH8,B4GALT1,BMP4,BMP5,C3,CAV3,CCBE1,CCDC40,CELSR1,CFL1,COL15A1,COL18A1,COL3A1,COL8A2,CREB3L1,CTSH,CTSZ,DAG1,DLG5,DLL1,EDNRA,ENG,EPHA1,ERBB2,ESRP2,EYA1,FMN1,FOLR1,FOXH1,FZD6,GATA3,GPX1,GTF2I,HOXA7,HPGD,HPSE,HSPG2,HYAL1,IRX3,ITGB8,JMJD8,KLHL3,LEPR,MAP2K5,MEGF8,MEIS1,MMP2,MYLK,MYO1E,NFIB,NOG,NPR1,NR2F2,OSR1,PIK3CB,PIK3R3,PKD2,PLXNB2,PRKD1,PTPRB,RAMP1,RAPGEF2,RARG,RNF213,RSPO2,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SHROOM3,SMAD3,SPARC,STARD13,STAT3,STIM1,STOX1,STRA6,TAL1,TGFBI,TGFBR3,TIE1,TNFSF12,TP63,VDR,VEGFB,WNT5A |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1880 | 155 | ABCA7,ABL1,ACKR3,ADARB1,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,APOE,AR,ARL6IP5,ASPSCR1,AXIN2,AZU1,BCOR,BMP4,BMP5,C3,CABIN1,CALCR,CALM3,CAPN3,CAV3,CCND3,CCR7,CD33,CD36,CD4,CDKN1C,CDKN2B,CELSR3,CHMP6,DAG1,DBNL,DKK1,DMPK,DOCK3,DUSP19,EFNA5,EID1,EIF2AK4,ENG,EPHA1,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGF7,FGR,FKBP8,FPR1,GATA3,GDF5,GMFB,GNAQ,GPER1,GPR183,GPRC5C,GRM1,HEXIM1,HEXIM2,HFE,HTR2C,IGF1R,IKBKB,IL27RA,IL6R,INHA,INPP5J,KAT2B,KLF15,LAMTOR1,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MECOM,MLLT1,MSTN,MTCP1,NDST1,NEK10,NNT,NOG,NR2F2,NSMF,PAK3,PAK6,PARP9,PBLD,PDCD4,PDE6G,PDGFC,PDGFD,PHLPP1,PIAS3,PIK3CB,PIK3R2,PIK3R3,PIN1,PIP5KL1,PKD2,PKHD1,PLCB1,PLCE1,PLXNB2,PMEPA1,POMT1,PPP1R35,PPP6R2,PRKCD,PRKD1,PRMT6,PRR7,PSCA,PTPA,PTPN22,PTPRC,PYGO2,RAF1,RAMP1,RAPGEF2,RARRES2,RBPMS,RCAN1,RCAN3,RNF180,ROS1,SENP2,SERPINF2,SNX25,SOCS5,STAT3,STOX1,STRADA,STYX,TAB1,TAL1,TNFAIP8L3,TNKS1BP1,TP53,TRABD2A,TRABD2B,TSPYL2,VEGFB,VPS28,WNK3,WNT5A,ZBED3,ZBTB7B |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1652 | 1716 | 146 | ABL1,ACE2,ADA,ADARB1,ADGRG1,AGGF1,AGT,ALDH3A1,ALOX15B,ANGPT1,ANKRD2,APLN,APOE,APPL2,AR,ASCL1,ATOH8,AXIN2,B4GALT1,BAD,BMP4,BMP5,BOK,BTG2,C1orf56,CAV3,CCND3,CD33,CD4,CDKN1C,CDKN2B,CLDN7,COL18A1,CRIP2,CTLA4,CTSH,CTSZ,CXCL12,CYP27B1,CYP7B1,DACH1,DLG5,DLL1,DPP4,EID2,EPHA1,ERBB2,ESRP2,EYA1,F2R,FBLN1,FGF7,FGR,GATA3,GDF5,GPAM,GPER1,GPR183,GPX1,HPGD,HPSE,HYAL1,IGF1R,IGFBP5,IL6R,INHA,INPP5D,INPPL1,KANK2,KAT2B,KLHL41,LAMB1,LDOC1,LIMS2,LRRK2,MAP2K5,MARCKSL1,MCC,MEIS1,MITF,MMP12,MMP2,MSTN,NACC2,NFIB,NMB,NOG,NPR1,NPR3,NR2F2,OSR1,P3H2,PBLD,PBRM1,PDCD4,PDE1A,PDGFC,PDGFD,PDPN,PKD2,PKHD1,PLAAT4,PLAC8,PLXNB1,PLXNB3,POU3F3,PPARD,PRKD1,PTGER2,PTPN22,PTPRC,PTPRU,PURA,PYGO2,RAF1,RAPGEF2,RARG,REST,SELENON,SERPINF1,SERPINF2,SGPP2,SIX5,SMAD3,SMARCA2,SPARC,STAT3,STOX1,TAL1,TAX1BP3,TGFBR3,TGM1,TNFSF12,TNS2,TNS3,TOB2,TP53,TP63,TPM1,VDR,VEGFB,VIPR1,WFDC1,WNT5A,ZBTB16,ZBTB7B |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 710 | 86 | ABCD1,ACADL,ACLY,ACSF3,ADGRF5,AGPAT1,AGPAT4,AJUBA,ALDH3B1,ALOX15B,APOC3,APOE,ARF3,ASAH1,B3GALT4,B4GALT6,BMP5,C3,CBR4,CERS6,CPNE7,CYP17A1,CYP27B1,CYP2E1,CYP7B1,DECR2,DGKA,DKK3,DKKL1,DOLK,DPM3,ELOVL3,ELOVL5,GIP,GPAM,GPD1,GPER1,HACD1,HACD2,HPGD,HSD17B1,HSD3B7,HTR2C,INPP5D,INPP5J,INPPL1,ISYNA1,LPGAT1,LPIN3,MPPE1,MTMR4,OSBPL9,PCYT2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PITPNM2,PITPNM3,PLCE1,PLD1,PLEKHA1,PLSCR1,PNPLA3,PPARD,PRKCD,PRKD1,PTGDS,REST,RUFY1,SCP2,SGPP2,SLC27A2,SPTSSA,ST3GAL6,ST6GALNAC5,ST6GALNAC6,STAR,TBXAS1,TRERF1,VDR |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 1652 | 1680 | 143 | ABCA12,ABCC3,ABL1,ACLY,ACTN1,ACTN4,ACTR1B,ADA,AGL,AGT,ALDH3B1,ALOX15B,ANGPT1,ANPEP,APLN,APOE,ARPC5,ARSA,ASAH1,ATP8B4,AXL,AZU1,B4GALT1,BACE1,BAD,C3,CADM1,CADPS2,CALM3,CCR7,CD33,CD36,CEL,CLEC3B,CNN2,CNR1,CPE,CPPED1,CR1,CREB3L1,CRISP3,CRISPLD2,CRP,CTSH,CTSS,CTSZ,CXCL12,DBNL,DPP4,EFNA5,ENG,EPHA5,F2R,F2RL1,FCGR2A,FFAR3,FGF7,FGR,FPR1,GATA3,GIP,GPAM,GPER1,HADH,HFE,HGSNAT,HMGN3,HPSE,HTR2C,IL17RC,IL27RA,INHA,ISLR,ITIH3,ITSN1,JAGN1,KCNN4,KMO,LAMTOR1,LAX1,LRRK2,MAPK3,MAVS,METTL7A,MME,MMP12,MMP25,MTTP,MYO18A,MYOM1,NFAM1,NMB,NPR1,NPR3,OLR1,OR51E2,ORM1,PADI2,PCSK6,PLAC8,PLD1,PNKD,PPARD,PRKCD,PTPN22,PTPRB,PTPRC,RAB11FIP3,RAF1,RARRES2,REST,SELENOP,SERPINA3,SERPINF2,SIDT2,SLC1A1,SLC27A2,SNCAIP,SPARC,SSC5D,STEAP3,SV2A,SYN2,SYT12,SYTL1,TAGLN2,TEX264,TLN1,TLR1,TMEM63A,TRPC4,TRPM2,UNC13C,USF2,VAMP8,VDR,VEGFB,VPS33B,VPS41,VWF,WNK3,WNT5A,ZBTB7B |
| GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 373 | 60 | ABL1,ADAM12,ADAMTS2,ADAMTSL4,AGT,APBB2,B4GALT1,BGN,BMP1,CCDC80,COL12A1,COL14A1,COL15A1,COL18A1,COL1A1,COL1A2,COL23A1,COL3A1,COL4A5,COL5A2,COL8A2,COL9A2,COL9A3,CREB3L1,CRISPLD2,CTSS,DAG1,DPP4,EFEMP2,EGFL6,ENG,FBLN1,FBLN2,FSCN1,GPM6B,HSPG2,ITGA11,ITGB4,ITGB8,KAZALD1,LAMA3,LAMB1,LAMB2,LOXL3,MMP12,MMP2,MMP25,MMP28,MMP7,MYO1E,NTN4,PDPN,PHLDB1,POMT1,SERPINF2,SMAD3,SPARC,TGFBI,TLL1,VWF |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1005 | 103 | AASS,ABCD1,ACAD10,ACADL,ACADS,ADGRF5,ADI1,ADO,AGL,AIFM3,ALDH1L1,ALDH3A1,ALDH3B1,ALDH9A1,ALOX15B,AOC2,AOC3,APPL2,AUH,BDH2,BLOC1S1,CBR4,CNR1,COQ9,CPOX,CPT2,CYB561,CYB561A3,CYB561D1,CYGB,CYP17A1,CYP20A1,CYP27B1,CYP2C18,CYP2E1,CYP4B1,CYP7B1,DDO,DECR2,DHRS1,DHRS13,DNAJC15,DPYD,ECHDC2,ECI2,ENO3,ETFB,FAHD1,FMO1,FMO2,FMO3,GPD1,GPX1,GPX8,GSTA1,GYG2,HADH,HPD,HPGD,HSD17B1,HSD3B7,IVD,KDM8,KMO,LDHD,LEPR,LOXL3,MAOA,MARC2,MSRB1,MSRB2,MTFR1L,NDUFV2,NNT,OGFOD2,OGFOD3,P3H2,P4HTM,PEX13,PPARD,PPP1CB,PRODH,PRXL2A,PYGM,PYROXD2,RDH11,RDH14,SARDH,SCP2,SDHC,SELENBP1,SELENON,SESN1,SLC27A2,STEAP3,SUCLG2,SUMF1,TBXAS1,TP53,TRABD2A,TRABD2B,TXN2,WDR93 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1318 | 121 | ABCD1,ACOT11,ADA,ADAMTS7,ADCY6,ADGRG1,AGT,ANGPT1,ANGPT2,ANGPT4,APLN,APOC3,APOE,APPL2,ASCL1,ATP1A2,AXIN2,AXL,BCOR,BMP4,BMP5,CACNB3,CAV3,CD33,COL3A1,COL5A2,CREB3L1,CTLA4,CTSZ,CUEDC2,DAND5,DGUOK,DKK1,DLL1,EFEMP1,EIF2AK4,ERBB2,ERBIN,F2R,F2RL1,GATA3,GDF5,GTF2I,HFE,HOXA7,HSPG2,IGFBP5,IKBKE,IL27RA,INHA,INPP5D,INPP5J,IRX3,KCNE3,LIMS2,LNPEP,LOXL3,LRRK2,MAFB,MAP2K5,MAVS,MC1R,MCC,MEIS1,MLIP,MSTN,NFIB,NLGN3,NLRX1,NOG,NPR1,NPR3,NR2F2,ORM1,OSR1,PARP3,PBLD,PDCD4,PIAS3,PIK3R1,PIN1,PLAC8,PPM1B,PRKCD,PTPN22,PTPRC,PTPRO,RAB11FIP3,RANBP3L,RAPGEF2,RARG,REST,RSPO2,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SMAD3,SOCS5,SPARC,SSC5D,STARD13,STAT3,TAL1,TBX18,TIE1,TOB2,TP53,TP63,TRIM46,TSPAN8,TWIST2,UBA7,ULK2,WNK3,WNT5A,ZBTB16,ZBTB7B |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1428 | 127 | ABL1,ADA,ADAM12,ADGRL3,AGGF1,AGT,ALOX15B,ANGPT2,ANGPT4,AP2A1,APOE,AR,ASCL1,ATOH8,AXIN2,AXL,BAD,BHLHB9,BLOC1S5,BMP1,BMP4,BMP5,BRINP3,C3,CAPN3,CAV3,CCBE1,CD36,CD4,CDKL5,CNR1,COL1A1,CTSH,CUX2,CXCL12,CYP27B1,DAG1,DBNL,DKK1,DKKL1,DLG5,DLL1,DOCK1,EFNA5,EHD2,ENG,EPHA1,FAIM,FAM210B,FGF7,FLRT3,GATA3,GDF5,GPAM,GPER1,GPM6B,HPSE,HTR2C,HYAL1,IL6R,INPP5D,IRX3,ITGB8,ITSN1,JMJD8,LIMS2,LRRC24,MEGF8,MME,NCKIPSD,NLGN3,NOG,NSMF,OBSL1,OSR1,PAK3,PDE3A,PDGFD,PDPN,PHLDB1,PIN1,PKDCC,PLAAT4,PLCB1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPARD,PPP1R13L,PRKD1,PTPRC,RAC3,RANBP3L,RAPGEF2,RARRES2,REST,RIPOR2,SCARF1,SEMA3C,SEMA4A,SERPINF1,SERPINF2,SLITRK6,SMAD3,SOCS5,SOX5,STAR,STAT3,STIM1,STOX1,SULT1E1,TAL1,TGFBR3,TIE1,TNFSF12,TP53,TP63,TRIOBP,VDR,VEGFB,VIL1,WASHC5,WNT5A,ZBTB16,ZBTB7B,ZNF219 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 1029 | 104 | ABL1,ADA,ADGRF5,ANGPT1,APLN,AR,ATOH8,AXIN2,BCOR,BMP4,BMP5,CCDC40,CDKN1C,CELSR1,CFL1,COL12A1,COL1A1,COL5A2,CPT2,DAG1,DKK1,DLL1,DNMT3A,EDNRA,EFEMP1,EN1,ENG,EXT2,EYA1,FBLL1,FKBP8,FLRT3,FOLR1,FOXD3,FOXH1,FZD6,GATA3,GDF5,HOPX,HOXA4,HOXA7,HYAL1,IFT140,IRX3,ITGB4,LAMA3,LAMB1,LOXL3,LPAR6,MAFB,MAP2K5,MAPK3,MEGF8,MMP2,MYO1E,NDST1,NECAB1,NOG,NR2F2,OSR1,PCSK6,PDGFC,PHLDB1,PIK3CB,PKD2,PKDCC,PLCB1,PLXNB2,POU3F4,PPP1R13L,PTPN18,PYGO2,RARG,RARRES2,RIPOR2,RSPO2,RXRA,SEMA3C,SENP2,SHROOM3,SLC35D1,SLITRK6,SMAD3,STOX1,STRA6,TAB1,TAL1,TBC1D32,TBX18,TFEB,TIE1,TMEM107,TP53,TP63,TRIOBP,TSHZ1,TTC39C,USP22,VAX2,WDR60,WNT5A,ZBTB16,ZIC1,ZNF358 |
| GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 654 | 80 | ABCD1,ACAD10,ACADL,ACADS,ACCS,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ALOX15B,AOAH,APOC3,APPL2,AUH,BDH2,BGN,C3,CBR4,CD36,CEL,CHST14,CKB,CNR1,CPT2,CYGB,CYP2C18,CYP2E1,CYP7B1,DAGLA,DECR2,ECHDC2,ECI2,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD5,ETFB,GIP,GPAM,GPD1,GPX1,GSTA1,GSTM2,HACD1,HACD2,HADH,HOGA1,HPGD,HSD3B7,IDNK,IVD,JMJD8,KMO,LDHD,LPGAT1,LPIN3,LYPLA2,MAPK3,MCCC1,OSBPL9,PDP2,PEX13,PFKFB1,PNKD,PNPLA3,PPARD,PTGDS,SCP2,SLC27A2,SLC27A4,STAR,STAT3,TBXAS1,TP53,UGT1A6,UGT2B11,ZBTB7A |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 1665 | 139 | ABL1,ADARB1,ADGRG1,AGT,AMOTL2,ANK2,AP2A1,APCDD1,APLN,APOE,AR,ATP1A2,AXIN2,BACE1,BAD,BMP4,C3,CACNB3,CADPS2,CALM3,CCN5,CD33,CEL,CELSR1,CELSR3,CNR1,CNTNAP4,COL1A1,CORT,CPE,CUX2,DAG1,DAGLA,DGKB,DKK1,DKK3,DKKL1,DLL1,DMPK,DNM1,DPP4,EFNA5,EIF2AK4,EIF4EBP2,EPHA5,F2R,FFAR3,FGF7,FOLR1,FZD6,GATA3,GDF5,GIP,GNAI1,GNAQ,GPER1,GRM1,HADH,HFE,HMGN3,HTR2C,INHA,INVS,IQSEC2,ITSN1,JAGN1,JRK,KCNJ3,KMO,LNPEP,LRRK2,LYNX1,LYPD1,MCC,MITF,MME,NLGN3,NMB,NOG,NOTUM,NSMF,NUDT3,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PDE6A,PDE6G,PDE7B,PIN1,PKD2,PLCB1,PLEKHG5,PNKD,PPARD,PPM1B,PRR7,PTPRA,PTPRO,PTPRU,PYGO2,RAB11FIP3,RAC3,RAF1,RAPGEF2,RARG,RBMS3,REST,RNF213,RSPO2,SCN2B,SEMA3B,SENP2,SIDT2,SLC1A1,SMAD3,SNCAIP,SPG11,SPIN1,STAR,STAT3,SV2A,SYN2,SYNPO,SYT12,TAX1BP3,TBX18,TLE2,TLE5,TP63,TRABD2A,TRABD2B,TSKU,UNC13C,VAMP8,VAX2,WNT5A,ZBED3,ZRANB1 |
| GO_HEART_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 589 | 75 | AGT,ALPK3,ANK2,APLN,ARMC4,ASCL1,AXIN2,BCOR,BMP4,BMP5,CAV3,CCDC40,COL3A1,CPE,CRIP1,DAND5,DKK1,DLL1,EDNRA,ENG,ERBB2,EYA1,FHOD3,FLRT3,FOLR1,FOXH1,GATA3,GPER1,HEXIM1,HSPB7,IFT140,JPH2,KAT2B,LDB3,MAP2K5,MAPK3,MB,MEGF8,MEIS1,MOSPD3,MYOM1,MYOM3,NDST1,NDUFV2,NEBL,NEK8,NOG,OBSL1,OSR1,PDCD4,PDLIM1,PIN1,PKD2,PLCE1,PPARD,PPP1R13L,PRICKLE4,RAF1,REST,RXRA,SEMA3C,SENP2,SMAD3,SPARC,STRA6,TAB1,TBC1D32,TGFBR3,TNNC1,TP53,TPM1,TRIP11,VEGFB,WNT5A,ZDHHC16 |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 725 | 84 | ABL1,AGT,ANGPT1,ANGPT2,ANGPT4,AP2A1,APLN,AR,ARPC5,ATP6V0A4,AXL,BCAR1,BMP5,CCBE1,CCND3,CD4,CD7,CHMP6,CHN1,COL1A1,COL4A5,CREB3L1,CRIM1,DLL1,DNM1,DOCK1,DOK1,EFEMP1,EFNA5,EIF4EBP2,EPHA1,EPHA5,ERBB2,ERBIN,ESRP2,FFAR3,FGF7,FGR,FLRT3,GATA3,GFRA1,GPER1,GRB7,IGF1R,IGFBP5,ITSN1,MAPK3,MMP2,MSTN,MYO1E,MYOF,NCOA5,NDST1,NOG,PAK3,PDE6G,PDGFC,PDGFD,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PLCB1,PLCE1,PLEKHA1,POLR2L,PRKCD,PRKD1,PSEN2,PTPN18,PTPRA,RAF1,RAPGEF2,RARRES2,ROS1,SH2D6,SLC2A8,SOCS5,STAT3,TIE1,VEGFB,VIL1,WNT5A,ZBTB7B |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 440 | 64 | AASS,ABCD1,ACAD10,ACADL,ACADS,ACSF3,ADA,ADO,ALDH1L1,ALDH3B1,APOBEC3C,APOBEC3G,APOE,AUH,BAD,BDH2,CEL,CNR1,CPT2,CYP27B1,DBT,DDO,DECR2,DPYD,DPYS,ECHDC2,ECI2,ENO3,ENTPD4,ENTPD5,ETFB,GPT,HADH,HOGA1,HPD,HYAL1,IDNK,IMPA2,INPP5A,INPP5J,IVD,KMO,KYAT1,LDHD,LPIN3,MCCC1,NUDT3,PEX13,PNKD,PPARD,PRODH,SARDH,SCARF1,SCP2,SHMT1,SLC27A2,SLC27A4,SULT1A1,SULT1B1,SULT1E1,TKTL1,TP53,TRERF1,TXN2 |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 594 | 75 | ACLY,ACSF3,ADA,ADCY6,ADGRF5,AGPAT1,AGPAT4,AJUBA,AK1,AK3,ARF3,CBR4,CKB,CPNE7,CTPS2,DGKA,DGUOK,DMAC2L,DOLK,DPM3,ELOVL3,ELOVL5,FCSK,GPAM,GPD1,GPER1,HACD1,HACD2,HTR2C,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,KMO,LPGAT1,LPIN3,MPPE1,MTMR4,NME3,NME4,NPR1,NUDT12,PANK1,PARP9,PCYT2,PDP2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PITPNM2,PITPNM3,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLEKHA1,PLSCR1,PNPLA3,PPARD,RUFY1,SHMT1,SLC25A1,SLC26A1,SLC26A2,STAT3,TK2,TPK1 |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 1365 | 122 | ABL1,ADARB1,ADCY6,AGT,AP2A1,APBB2,APOE,ASCL1,B4GALT6,BHLHB9,BLOC1S1,BLOC1S4,BLOC1S5,BMP4,BMP5,BRINP3,BTG2,C3,C8orf37,CDKL5,CDKN1C,CELSR3,CFL1,CHN1,CNR1,CNTNAP1,CNTNAP2,CSMD3,CTSZ,CUX2,CXCL12,DAG1,DBNL,DGUOK,DKK1,DLG5,DLL1,DNMT3A,DOK1,EFHD1,EFNA5,EIF2AK4,EMB,EN1,EPHA1,EPHA5,ERBB2,EYA1,FLRT3,FOLR1,GATA3,GDF5,GFRA1,GLDN,GPM6B,GRB7,HECW2,IFT140,INPP5J,IRX3,ITSN1,KLHL1,LAMB1,LAMB2,LHX8,LRRK2,LYPLA2,MAPK3,MEGF8,MEIS1,NANOS1,NCKIPSD,NFIB,NLGN3,NOG,NR2F6,NRBP2,NSMF,NTN4,OBSL1,PAK3,PIGT,PIK3CB,PIK3R1,PIN1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRA,PTPRO,RAC3,RAPGEF2,REST,RIPOR2,ROM1,RSPO2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SLITRK6,SPG11,SPTBN2,STAT3,TAL1,TENM2,TMC1,TRIM46,TRIO,TRIOBP,TRIP11,TSKU,ULK2,VAX2,VSTM2L,WASHC5,WNT5A |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 810 | 89 | ABL1,ACKR3,ACTA2,ADAM12,ADGRF5,ADGRG1,AGGF1,AGT,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANPEP,APLN,APOE,B4GALT1,BMP4,C3,CCBE1,COL15A1,COL18A1,COL1A1,COL1A2,COL3A1,COL8A2,CREB3L1,CTSH,DAG1,DLL1,EDNRA,ENG,EPHA1,ERBB2,EYA1,FOLR1,FOXH1,GPER1,GPX1,GTF2I,HOXA7,HPGD,HPSE,HSPG2,HYAL1,IL6R,ITGB8,JMJD8,LEPR,MAP2K5,MEGF8,MEIS1,MMP2,MYLK,MYO1E,NDST1,NOG,NPR1,NR2F2,OSR1,PDCD4,PDGFD,PDPN,PIK3CB,PIK3R3,PKD2,PRKD1,PTPRB,RAMP1,RAPGEF2,RNF213,ROM1,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SPARC,STARD13,STAT3,STIM1,STRA6,TAB1,TAL1,TGFBI,TGFBR3,TIE1,TNFSF12,VEGFB,WNT5A |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1652 | 1698 | 139 | ABL1,ADA,ADCY6,ADGRL3,AGT,ALDH3A1,ANGPT2,APOE,APPL2,AR,ASCL1,ATP1A2,ATP6V0A4,AXL,BACE1,BAD,BCAR1,BRINP3,BTG2,CALCR,CALM3,CCND3,CCR7,CD36,CD4,CFL1,CLDN7,CNR1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A2,CTSH,CXCL12,CYP27B1,CYP2E1,DAG1,DKK1,DNM1,DNMT3A,EDEM3,EFNA5,EIF4EBP2,EPHA5,ERBIN,F2R,FAM210B,FCSK,FFAR3,FMO1,FOLR1,GATA3,GDAP1,GIP,GNA14,GNAI1,GNAQ,GPAM,GPD1,GPER1,GPX1,HADH,HMGN3,HPGD,HTR2C,HYAL1,IGF1R,IGFBP5,INPPL1,JAGN1,KANK2,KAT2B,KLF15,KLHL22,KMO,LAMTOR1,LDOC1,LPIN3,LRRK2,LYPD1,MAPK3,MB,MGST2,MMP12,MMP2,MSTN,MYD88,NCOA5,NR2F2,NSMF,OR51E2,OSR1,P2RY11,PDCD4,PDE3A,PDGFC,PDGFD,PFKFB1,PIK3R1,PIK3R2,PIK3R3,PKD2,PLCB1,PLEKHA1,PLSCR4,PPARD,PRKCD,PRKD1,PTGER2,PTPN22,PTPRA,RAF1,RAPGEF2,RARG,RARRES2,RDH11,RECQL5,RORC,RXRA,SERPINF1,SESN1,SHMT1,SIDT2,SLC2A8,SPAAR,SPARC,STAR,STAT3,TGFBR3,TIE1,TP53,TPM1,TRPM2,TXN2,VDR,WFDC1,WNT5A,ZBTB7B |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 1163 | 109 | ABL1,ACTN4,ADA,ADAM12,AGGF1,AGT,ANGPT2,ANGPT4,AP2A1,APOE,AR,ARPIN,BCOR,BHLHB9,BMP4,C3,CAV3,CCBE1,CD36,CDKL5,CELSR1,CELSR3,CFL1,CHN1,COL5A2,CREB3L1,CTSH,CUX2,CXCL12,DAG1,DBNL,DKK1,DLL1,DOCK1,EFNA5,EHD2,ENG,EPHA1,ERBB2,EYA1,FBLN1,FGD3,FGD4,FGF7,FGR,FZD6,GATA3,GTF2I,HECW2,HSPG2,HYAL1,INF2,ITGB8,JMJD8,LIMS2,LRRK2,MAP2K5,MEGF8,NFIB,NLGN3,NOG,NPR1,NSMF,NTN4,OBSL1,OMA1,OSR1,PAK3,PALM2AKAP2,PALMD,PARVB,PDPN,PHLDB1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRO,RAC3,RAPGEF2,RHOBTB2,RIPOR2,RSPO2,RXRA,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SHROOM3,SPARC,STARD13,STAT3,STIM1,STOX1,TBX18,TIE1,TNFSF12,TPM1,TRIM46,TRIOBP,ULK2,VDR,VEGFB,VIL1,WNT5A,ZMYM3,ZRANB1 |
| GO_NEURON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 1114 | 106 | ABL1,ADARB1,ADCY6,AGT,AP2A1,APBB2,APOE,ASCL1,B4GALT6,BHLHB9,BLOC1S1,BLOC1S4,BLOC1S5,BMP5,BTG2,C3,C8orf37,CDKL5,CDKN1C,CELSR3,CFL1,CHN1,CNR1,CNTNAP1,CNTNAP2,CSMD3,CTSZ,CUX2,CXCL12,DAG1,DBNL,DGUOK,DKK1,DLG5,DOK1,EFHD1,EFNA5,EIF2AK4,EMB,EN1,EPHA1,EPHA5,ERBB2,FLRT3,FOLR1,GATA3,GFRA1,GLDN,GPM6B,GRB7,HECW2,IFT140,INPP5J,ITSN1,KLHL1,LAMB1,LAMB2,LHX8,LRRK2,LYPLA2,MAPK3,MEGF8,NANOS1,NCKIPSD,NFIB,NLGN3,NOG,NR2F6,NSMF,NTN4,OBSL1,PAK3,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRA,PTPRO,RAC3,RAPGEF2,RIPOR2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SLITRK6,SPG11,SPTBN2,TENM2,TMC1,TRIM46,TRIO,TRIOBP,TRIP11,TSKU,ULK2,VAX2,VSTM2L,WASHC5,WNT5A |
| GO_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 1652 | 1442 | 124 | ABL1,ACLY,ACTR1B,ADA,ADGRF5,AGL,ALDH3B1,ANPEP,APOE,ARPC5,ARSA,ASAH1,ATP8B4,AXL,AZU1,B4GALT1,BAD,BLOC1S4,BMP4,C3,CAPN3,CCND3,CCR7,CD33,CD36,CD4,CD7,CNN2,CNR1,COL1A1,COL1A2,COL3A1,CPPED1,CR1,CRISP3,CRISPLD2,CTLA4,CTSH,CTSS,CTSZ,CXCR5,CYGB,DBNL,DGKA,DGKB,DLG5,DLL1,DOCK11,DPP4,EIF2AK4,ERBB2,F2R,F2RL1,FCGR2A,FGR,FLOT2,FPR1,FZD6,GATA3,GNA14,GNAQ,GPAM,GPER1,GPR183,HFE,HGSNAT,HPSE,HSH2D,IGHV3-73,IL27RA,INHA,INPP5D,LAMTOR1,LAX1,LEPR,LOXL3,LRRK2,LY6D,MAFB,MAPK3,METTL7A,MME,MMP25,MYL9,MYO18A,NFAM1,OLR1,ORM1,PADI2,PAK3,PARP3,PDPN,PIK3CB,PIK3R1,PLAC8,PLCB1,PLD1,PLSCR1,PRKCD,PRR7,PTPN22,PTPRB,PTPRC,PURA,RAF1,RIPOR2,RORC,SEMA4A,SERPINA3,SLC27A2,SMAD3,SOCS5,STAT3,TLN1,TLR1,TMEM63A,TP53,TRPM2,VAMP8,VWF,WNT5A,ZBTB16,ZBTB7A,ZBTB7B |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 547 | 70 | ACADL,ACLY,ALDH3B1,AOC2,APOE,APOL1,APOL2,ASAH1,BMP5,CBR4,CEL,CETP,CYP27B1,CYP2E1,CYP7B1,DKK3,DKKL1,EBPL,GATA3,GPAM,GPD1,GPER1,HSD3B7,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,LDHD,LEPR,LIMA1,MAOA,MC1R,MYOF,NPR1,NUDT3,OSBPL5,OSBPL9,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD4,PNKD,PPARD,RAPGEF2,RDH11,RDH14,REST,RNF180,RXRA,SCARF1,SCP2,SGPP2,SLC24A5,SLC27A2,SLC5A3,SNCAIP,STAR,SULT1A1,SULT1B1,SULT1E1,TP53,TRERF1,TTC39B,VDR,WNT5A |
| GO_GLYCEROLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 414 | 60 | ABHD4,AGPAT1,AGPAT4,AJUBA,APOC3,APOE,ARF3,C3,CAV3,CETP,CISH,CPNE7,CYP2E1,DAGLA,DBI,DGKA,DGKB,DPM3,GPAM,GPD1,GPX1,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,LPGAT1,LPIN3,MPPE1,MTMR4,OSBPL5,PCYT2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLEKHA1,PLSCR1,PNPLA3,RUFY1,SOCS5,TTC7A |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 671 | 78 | ABCA7,ACLY,ACSF3,ADA,ADCY6,AK1,AK3,ALG6,ALG9,ANGPT1,AP2A1,B3GALT4,B3GLCT,B3GNT10,B4GALNT2,B4GALT1,B4GALT6,BGN,CBR4,CCR7,CHST14,CHST9,CTPS2,DMAC2L,DOLK,DPM3,DPY19L4,EDEM3,ELOVL3,ELOVL5,ENTPD5,EXT2,EXTL1,FCSK,FUT11,GALNT5,HACD1,HACD2,HS3ST3B1,HS6ST3,HSPG2,HYAL1,MGAT4B,MGAT4C,MPPE1,MUC15,NDST1,NDST4,NECAB1,NME3,NME4,NPR1,PANK1,PDP2,PIGB,PIGQ,PIGS,PIGT,PLCB1,POMT1,RAMP1,SHMT1,SLC25A1,SLC26A1,SLC26A2,SLC35D1,ST3GAL3,ST3GAL6,ST6GALNAC2,ST6GALNAC5,ST6GALNAC6,STAT3,TK2,TMTC1,TMTC4,TRIP11,VEGFB,XXYLT1 |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 1604 | 132 | ABCA12,ABCA4,ABCA7,ABCA8,ABCC3,ABCC6,ABCD1,ABL1,ACTN4,AGT,ANK2,ANO2,ANO8,APOL1,APPL2,AQP7,ARL6IP5,ASPSCR1,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BEST2,BEST4,C3,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CLCA2,CLCNKA,CLIC3,CNGB3,CPT2,CTSS,DMAC2L,DNAJC15,EDNRA,EMB,F2R,FOLR1,FXYD3,GIP,GPER1,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,KLF15,MFSD4A,NALCN,NIPAL2,NLGN3,NNT,OSR1,PDPN,PDZK1,PEX13,PIK3R1,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PPARD,PSEN2,PTPRC,RAF1,RHAG,SCN1A,SCN2B,SCNN1B,SELENON,SLC12A9,SLC13A4,SLC15A2,SLC16A14,SLC16A7,SLC1A1,SLC20A2,SLC22A5,SLC24A5,SLC25A1,SLC26A1,SLC26A2,SLC2A14,SLC2A8,SLC35A4,SLC35D1,SLC35E3,SLC37A2,SLC38A10,SLC41A3,SLC43A3,SLC46A3,SLC49A3,SLC4A2,SLC5A2,SLC5A3,SLC7A7,SLC9A9,SLCO1B1,SLCO2A1,SLCO6A1,STAC2,STEAP3,STIM1,STIMATE,STRA6,SV2A,TMC1,TMEM266,TMEM63A,TPCN2,TRPC4,TRPM2,UCP2,UTRN,WNK3 |
| GO_PHOSPHOLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 432 | 61 | ABHD4,ADGRF5,AGPAT1,AGPAT4,AJUBA,ARF3,CCR7,CETP,CISH,CPNE7,DBI,DGKA,DOLK,DPM3,FGR,GPAM,GPD1,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,LPGAT1,LPIN3,MPPE1,MTMR4,OSBPL5,PCYT2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCH2,PLD1,PLEKHA1,PLSCR1,PNPLA3,PPARD,PRKCD,PRKD1,RUFY1,SOCS5,TNFAIP8L3,TTC7A,WDR81 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1652 | 1026 | 99 | ABCA7,ABL1,ACKR3,ACTN4,ADA,ADGRG1,AGT,AJUBA,ANGPT1,APOE,APOL3,AR,ARL6IP5,AXL,BAD,BMP4,BOK,CALCR,CALM3,CCR7,CD36,CD4,COL3A1,CXXC5,DBNL,DKK1,DLG5,DUSP19,ENG,ERBB2,F2R,F2RL1,FGF7,FGR,FPR1,GATA3,GIP,GPER1,GPR183,GPX1,GRM1,GSTM2,HEXIM1,HPSE,HTR2C,IGF1R,IGFBP5,IKBKB,IKBKE,ITSN1,JMJD8,JPH2,KLHL22,LAMTOR1,LPAR6,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MC1R,MIOS,MYD88,NACC2,NDST1,NEK10,NPR1,OR51E2,PAK3,PDCD4,PDE6G,PDGFC,PDGFD,PIK3CB,PIK3R1,PIK3R2,PKD2,PLCB1,PLCE1,PLEKHF1,PLEKHG5,PLXNB1,PPARD,PRKD1,PTPN22,PTPRC,RAF1,RAPGEF2,SECTM1,SERPINF2,STIMATE,STOX1,TAB1,TMEM9B,TNFAIP8L3,TP53,TRIM22,WNT5A |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1859 | 144 | AASS,ABCA7,ACCS,ACLY,ACSF3,ADA,ADCY6,ADI1,AGPAT1,AGPAT4,AK1,AK3,ALDH3B1,ALDH9A1,ALG6,ALG9,ANGPT1,AP2A1,APOE,ASAH1,ASPG,AZU1,B3GALT4,B3GLCT,B3GNT10,B4GALNT2,B4GALT1,B4GALT6,BDH2,BGN,BTG2,CBR4,CCR7,CD4,CERS6,CHST14,CHST9,CKB,CNOT11,CPOX,CTPS2,DGUOK,DMAC2L,DOLK,DPM3,DPY19L4,DPYD,EDEM3,EIF2AK4,EIF4EBP2,EIF4G3,ELOVL3,ELOVL5,ENTPD5,ERBB2,EXT2,EXTL1,FOLH1,FUT11,GALNT5,GATA3,GPAM,GPT,GRB7,GSTA1,GSTA2,GSTM2,GSTT2B,HACD1,HACD2,HS3ST3B1,HS6ST3,HSPG2,HYAL1,IARS2,IGFBP5,INHA,INPP5D,KMO,KYAT1,LPIN3,MAP2K5,MAPK3,MGAT4B,MGAT4C,MGST2,MPPE1,MRPL41,MUC15,NANOS1,NDST1,NDST4,NECAB1,NME3,NME4,NPR1,NUDT12,PANK1,PARP9,PCIF1,PDP2,PIGB,PIGQ,PIGS,PIGT,PLCB1,PLSCR1,POMT1,PPM1B,PRKCD,PRKD1,PRR16,PTPRC,PURA,PYM1,RAMP1,RBMS3,RPL39P5,RXRA,SGPP2,SHMT1,SLC25A1,SLC26A1,SLC26A2,SLC35D1,SPTSSA,ST3GAL3,ST3GAL6,ST6GALNAC2,ST6GALNAC5,ST6GALNAC6,STAT3,TK2,TLR1,TMTC1,TMTC4,TPK1,TRIP11,VEGFB,XXYLT1,ZC3H12D,ZDHHC12,ZDHHC16,ZDHHC21 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1670 | 134 | ABL1,ADA,ADGRF5,ANGPT1,APOBEC3G,APOE,APPL2,ARPC5,AXL,BAD,BCAR1,BMP4,BMP5,BTN3A3,C1R,C1RL,C3,C4A,C4B,CACNB3,CADM1,CCL28,CCR7,CD33,CD36,CD4,CD99L2,CFB,CNR1,COL1A1,COL1A2,COL3A1,CR1,CRP,CTLA4,CTSH,CTSS,CUEDC2,CXCL12,DLG5,DLL1,DOCK1,DPP4,EIF2AK4,ERBB2,ERBIN,F2RL1,FAM210B,FCGR2A,FFAR3,FGR,FLOT2,FPR1,GATA3,GCSAM,GPAM,GPER1,GPR183,GPX1,H3-3A,H3C6,HEXIM1,HFE,HOXA7,IGHV3-73,IKBKB,IKBKE,IL1R1,IL27RA,IL6R,INHA,INPP5D,KAT2B,KCNN4,LAX1,LOXL3,LRRK2,MAFB,MAPK3,MAVS,MEIS1,MITF,MMP12,MMP28,MSTN,MUC15,MYD88,MYL9,MYO18A,NCKIPSD,NFAM1,NFE2,NLRX1,ORM1,P4HTM,PADI2,PAK3,PARP3,PARP9,PDGFD,PHLPP1,PIAS3,PIK3CB,PIK3R1,PIK3R2,PLCB1,PLEKHA1,PLSCR1,PPM1B,PRKCD,PRMT6,PRXL2A,PTPN22,PTPRC,PVRIG,RAF1,RARG,RARRES2,RIPOR2,SIAE,SMAD3,SOCS5,SPPL2B,STAT3,TAB1,TAL1,TLR1,TOB2,TP53,VAMP8,VEGFB,WNT5A,ZBTB16,ZBTB7B |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 1220 | 109 | ABCA7,ABL1,ACE2,ACTN4,ACTR3B,ADGRL3,AGT,AJUBA,ANAPC11,ANGPT1,AP2A1,APLN,APOE,APPL2,AR,ARPC5,ARPIN,AXL,BAD,BHLHB9,BMP5,BOK,C3,CAV3,CCR7,CD36,CDKL5,CFL1,CNR1,CUX2,CXCL12,DAG1,DBNL,DLG5,DLL1,DNM1,DOCK1,DOCK11,EFNA5,EHD2,EPHA1,ERCC5,F2RL1,FHOD1,FLRT3,FMN1,FSCN1,GATA3,GMFB,GPER1,GPX1,GTF2H5,HFE,HSPA1L,HYAL1,IGF1R,ITSN1,JCHAIN,LIMS2,LMOD1,LRRC24,LRRK2,MAPK3,MEGF8,MSTN,NCKIPSD,NLGN3,NPHP1,OBSL1,PAK3,PAN2,PDPN,PHLDB1,PIP4K2B,PLCB1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKCD,PRKD1,RAC3,RAPGEF2,RIPOR2,SCARF1,SEMA4A,SERPINF1,SERPINF2,SLITRK6,SMAD3,ST20,SYNPO,TAL1,TASOR,TBC1D5,TENM2,TP53,TP63,TPM1,TRABD2A,TRABD2B,TRIOBP,UBXN2B,VIL1,VPS13C,VPS28,WASHC5,WNT5A,ZBTB7B |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 748 | 81 | ABL1,ACTN1,ACTN4,ADARB1,AKIP1,APBB2,APOE,AR,AXL,B4GALT6,BHLHB9,C8orf37,CDKL5,CELSR3,CFL1,CHN1,COL12A1,COL14A1,COL18A1,CUX2,CXCL12,DAG1,DBNL,DKK1,DOCK1,DOK1,EFNA5,EMB,EPHA1,EPHA5,ERBB2,FBLN1,FLRT3,FRMD6,GATA3,GFRA1,GRB7,HECW2,LAMB1,LAMB2,LIMS2,LRRK2,LYPLA2,MAPK3,MEGF8,NFIB,NLGN3,NOG,NSMF,NTN4,OBSL1,PAK3,PARVB,PDPN,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRA,PTPRO,RAC3,RAPGEF2,RIPOR2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLITRK6,SPG11,SPTBN2,TAL1,TRIM46,TRIO,TRIOBP,TSKU,ULK2,VAX2,VSTM2L,WNT5A |
| GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 320 | 51 | ABHD4,AGPAT1,AGPAT4,AJUBA,ARF3,CETP,CISH,CPNE7,DBI,DGKA,DPM3,GPAM,GPD1,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,LPGAT1,LPIN3,MPPE1,MTMR4,OSBPL5,PCYT2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCH2,PLD1,PLEKHA1,PLSCR1,PNPLA3,RUFY1,SOCS5,TTC7A |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1652 | 1779 | 138 | ACE2,ADAM12,ADAM21,ADAMTS2,ADAMTS7,ADAMTSL4,AGBL2,AGBL4,AGBL5,AGT,ANAPC11,ANAPC16,ANPEP,ANXA8,ANXA8L1,APOE,AR,AREL1,ARL6IP5,AZU1,BACE1,BAD,BEX3,BMP1,BOK,C1R,C1RL,C3,C4A,C4B,CAAP1,CAPN3,CAV3,CCBE1,CFB,CLCA2,CLEC3B,CPA3,CPA5,CPE,CR1,CRIM1,CTSH,CTSO,CTSS,CTSZ,CUL9,DAG1,DET1,DPP4,EDEM3,F2R,FBLN1,FBXL15,FBXL17,FBXL19,FBXL22,FBXO9,FOLH1,GAS1,GATA3,GPER1,GPX1,HECW2,HERC2,HFE,ITIH3,KAT2B,KDM8,KLHL22,KLHL3,LMLN,LNPEP,LRRK2,MAP2K5,MAPK3,MINDY1,MME,MMP12,MMP2,MMP25,MMP28,MMP7,NEDD8,OLR1,OMA1,OVCH1,PANO1,PAPLN,PCOLCE,PCOLCE2,PCSK6,PCSK7,PRR7,PRSS36,PSEN2,RAF1,REST,RHBDL2,RNF150,RNF180,RNF213,SCRN2,SENP2,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SMAD3,SOCS5,SPINK9,SPPL2B,SSPO,ST20,STAT3,STYX,TAB1,TLL1,TMEM129,TMPRSS5,TP53,TP63,TRABD2A,TRABD2B,UBA7,UBE3B,UBXN2B,USP22,USP54,VIL1,VPS28,VPS37D,WDR81,WFDC1,WFDC8,ZRANB1,ZYG11B |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 723 | 79 | AASS,ABCD1,ACADL,ACCS,ACLY,ACSF3,ADA,ADI1,ALOX15B,AP2A1,APOC3,APOE,ASAH1,ASPG,BDH2,BGN,BMP5,CBR4,CHST14,COQ9,CYP27B1,CYP2E1,CYP7B1,DECR2,DKK3,DKKL1,DPYD,ELOVL3,ELOVL5,ENO3,ENTPD4,FOLH1,GIP,GPAM,GPD1,GPER1,GPT,GPX1,HACD1,HACD2,HOGA1,HPGD,HSD3B7,HYAL1,IMPA2,IP6K3,ISYNA1,KAT2B,KMO,KYAT1,LEPR,LPGAT1,MGST2,NEIL1,NME3,NME4,NUDT12,NUDT13,NUDT3,OSBPL9,PDE1A,PDE7B,PDE8B,PFKFB1,PLCB1,PLCD4,PLCE1,PLCH2,PTGDS,REST,SCP2,SHMT1,SLC25A1,SLC27A2,SLC35D1,STAR,TBXAS1,TK2,VDR |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1652 | 1781 | 138 | ABL1,ACTN4,ADCY6,AGFG2,AGT,AJUBA,ANGPT1,ANGPT4,ANK2,APOE,AR,ARL6IP5,AZU1,BAD,BEX3,BMP4,BOK,CACNB3,CALM3,CAPN3,CASQ1,CCND3,CCR7,CD33,CD36,CD4,CDKL5,CHN1,CR1,CTSH,CTSS,CYP27B1,DAG1,DBNL,DKK1,DNAJC15,DOCK1,DOCK11,DOCK3,DUSP19,EDNRA,EFNA5,EPHA1,EPHA5,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGR,FLOT2,FPR1,GATA3,GMFB,GNAQ,GPER1,GPRC5C,GRM1,GSTM2,HFE,IKBKB,IL6R,ITSN1,JPH2,KCNE3,LPAR2,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MGST2,MTCP1,MTSS2,MYD88,NEK10,NFAM1,NLGN3,NPR3,PAK3,PAK6,PARP9,PCOLCE,PCOLCE2,PDE6G,PDGFC,PDGFD,PDP2,PDZK1,PFKFB1,PIK3CB,PIN1,PKD2,PLAAT4,PLCB1,PLCE1,PLEKHG6,PLSCR1,PLXNB1,PRKCD,PRKD1,PRR7,PSEN2,PTPA,PTPRC,PYGO2,RAF1,RANBP3L,RAPGEF2,REST,RIN2,RIPOR2,SMAD3,ST20,STAC2,STARD13,STAT3,STIM1,STIMATE,STK36,STOX1,STRADA,TAB1,TAL1,TAX1BP3,TBC1D2B,TBC1D5,TBC1D9,TNFAIP8L3,TPM1,TRIM22,TRIM37,VDR,WDR60,WNK3,WNT5A,ZBTB7A |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1673 | 132 | ABCA7,ABCD1,ACADL,AJUBA,ANKRD2,AP2A1,APOC3,APOE,AR,ARID4A,ASCL1,ATAD2B,ATOH8,BCOR,BEND5,BMP4,BMP5,BTG2,CAPN3,CC2D1B,CCND3,CD36,CDKN1C,CIPC,CREB3L1,CUX2,CXXC5,CYGB,CYP27B1,DACH1,DKK1,DKK3,DKKL1,DNMT3A,DPF3,EID1,EID2,EIF2AK4,EIF4EBP2,EN1,FOXD3,FOXH1,GATA3,GCHFR,GLIS1,GPER1,GRB7,H3-3A,H3C6,HEXIM1,HEXIM2,HOXA7,IGFBP5,INHA,INPP5D,KANK2,KCNIP3,KCTD1,KDM8,LEPR,LOXL3,MAP2K5,MECOM,MITF,MLIP,MMP12,NACC2,NANOS1,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,NR2F6,OSR1,PARP3,PARP9,PCIF1,PDCD4,PIAS3,PLCB1,POU3F3,PPARD,PPP1R13L,PRMT6,PTPRC,PURA,RAPGEF2,RARG,RECQL5,REST,RORC,RXRA,SHMT1,SIX5,SLC24A5,SMAD3,SMARCA2,SOX5,STAT3,TAL1,TASOR,TBX18,TCEAL1,TENM2,THRA,TLE2,TLE5,TOB2,TP53,TP63,TRIM22,TRIM29,TRIM37,TSPYL2,TWIST2,VAX2,VDR,WNT5A,ZBTB16,ZBTB37,ZBTB7A,ZBTB7B,ZC3H12D,ZC3H4,ZHX1,ZNF217,ZNF219,ZNF366,ZNF497,ZNF776 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1047 | 98 | ABL1,ACTN4,ADAMTS7,ADCY6,ADGRG1,AGT,ANGPT2,ANGPT4,ANKRD2,APOE,APPL2,ARPIN,ASCL1,AXIN2,BCOR,BMP4,BMP5,CAV3,CETP,COL3A1,COL5A2,CREB3L1,CRP,CTLA4,CTSZ,DAND5,DGUOK,DKK1,DLL1,EFEMP1,EFNA5,EIF2AK4,ERBB2,FBLN1,GATA3,GDF5,GLIS1,GPER1,GTF2I,HOPX,HOXA7,HSPG2,IGFBP5,INHA,INPP5D,INPP5J,IRX3,LIMS2,LOXL3,LRRK2,MAFB,MAP2K5,MEIS1,MSTN,NFIB,NLGN3,NOG,NPR1,OMA1,OSR1,PARP3,PBLD,PDCD4,PIAS3,PIK3R1,PLAC8,PLPP7,PPARD,PTPRO,RANBP3L,RAPGEF2,RARG,REST,RSPO2,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SMAD3,SOCS5,SPARC,STARD13,STAT3,TAL1,TBX18,TIE1,TOB2,TP53,TP63,TRIM46,TRIO,TWIST2,ULK2,WNT5A,ZBTB16,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 1427 | 119 | ABL1,ACKR3,ADA,AGT,AJUBA,APCDD1,APLN,APOE,AR,AXIN2,BMP4,BMP5,BOK,CAAP1,CALM3,CAV3,CHMP6,CISH,CREB3L1,CXCL12,CYP7B1,DAG1,DAND5,DKK1,DKK3,DKKL1,DLG5,DLL1,DNM1,DUSP19,EID2,ERBB2,ERBIN,EYA1,F2RL1,FAIM,FBLN1,FOXH1,FZD6,GATA3,GNAI1,GPER1,GPX1,GSTM2,HADH,IGF1R,IGFBP5,INHA,INPP5D,INVS,JAGN1,KANK2,LAX1,LRRK2,LZTR1,MAP2K5,MCC,MECOM,MEGF8,MGRN1,MMP12,MSTN,MTMR4,NCOA5,NLGN3,NLRX1,NMB,NOG,NOTUM,PADI2,PBLD,PDCD4,PDE3A,PHLPP1,PIK3R2,PIN1,PKD2,PKHD1,PLEKHA1,PMEPA1,PNKD,PPM1B,PRKCD,PSCA,PTPN18,PTPN22,PTPRC,PTPRO,PTPRU,PVRIG,RAB11FIP3,RAF1,RASL11B,RBMS3,RCAN1,REST,RGS7BP,RIPOR2,RNF152,RNF213,SESN1,SMAD3,SNX25,SOCS5,SPAAR,TAX1BP3,TBX18,TGFBR3,TLE2,TLE5,TP53,TP63,TRABD2A,TRABD2B,TRIM59,TSKU,WNT5A,ZBTB7A,ZNF366 |
| GO_LIPID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 328 | 51 | ABCD1,ABHD4,ACAD10,ACADL,ACADS,AOAH,APOC3,APOE,ASAH1,ASPG,AUH,BDH2,CEL,CES4A,CNR1,CPT2,CYP27B1,DAGLA,DECR2,ECHDC2,ECI2,ETFB,HADH,IVD,LDAH,LGALS12,LPIN3,MGST2,PEX13,PLAAT2,PLAAT4,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLD4,PLIN1,PNPLA3,PPARD,PRKCD,RARRES2,SCARF1,SCP2,SLC27A2,SLC27A4,STS,SULT1E1,THRA,TRERF1 |
| GO_FATTY_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 380 | 55 | ABCD1,ACAD10,ACADL,ACADS,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ALOX15B,AOAH,APOC3,APPL2,AUH,BDH2,C3,CBR4,CD36,CEL,CNR1,CPT2,CYGB,CYP2C18,CYP2E1,DAGLA,DECR2,ECHDC2,ECI2,ELOVL3,ELOVL5,ETFB,GIP,GPAM,GPX1,GSTA1,GSTM2,HACD1,HACD2,HADH,HPGD,IVD,LPGAT1,LPIN3,LYPLA2,MAPK3,PDP2,PEX13,PNPLA3,PPARD,PTGDS,SCP2,SLC27A2,SLC27A4,TBXAS1 |
| GO_CIRCULATORY_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 554 | 67 | ACE2,ACTA2,ADA,ADCY6,AGT,ANGPT1,ANK2,APLN,APOE,AR,ATP1A2,ATP1A4,AZU1,CACNB3,CACNG8,CALM3,CASQ1,CAV3,CNR1,COL1A2,CPA3,CRP,CTNNA3,CTSZ,CXCL12,DLL1,DMPK,EDNRA,F2R,F2RL1,FFAR3,FXYD3,GPER1,GPX1,GSTM2,HSPB7,KCNE3,KCNE4,KCNIP3,KCNJ3,KCNK15,MME,MYOF,NAV2,NFE2,NPR1,NPR3,NR2F2,OLR1,OR51E2,PDE3A,PPARD,PPP1R13L,PTGER2,PTPRO,RCAN1,SCN1A,SCN2B,SERPINF2,SLC1A1,SMAD3,STIM1,THRA,TNNC1,TNNI2,TPM1,VEGFB |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1988 | 147 | ABCD1,ABL1,ACTA2,ACTN1,ACTN4,ADGRF5,AGT,AJUBA,APLN,APOE,AR,ARID4A,ASCL1,ATAD2B,ATOH8,AZU1,BMP4,BMP5,CAPN3,CARF,CCR7,CD36,CD4,CDKN1C,CDKN2B,COL1A1,CREB3L1,DLL1,DPF3,EBF1,EHF,EIF2AK4,ELOVL5,EN1,ENG,ERBB2,EYA1,F2R,F2RL1,FGF7,FHOD1,FOXD3,FOXH1,GATA3,GLIS1,GPER1,HMGN3,HOXA4,HOXA7,HOXC13,HTR2C,IKBKB,KAT2B,KDM8,KLF15,LHX8,LPGAT1,LPIN3,MAFB,MAP2K5,MAP3K12,MAPK3,MAVS,MC1R,MECOM,MEIS1,METTL23,MITF,MLIP,MMP12,MSTN,NAT14,NFE2,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,OSR1,PADI2,PAK3,PARP9,PCIF1,PDLIM1,PIK3R1,PIK3R2,PIN1,PKD2,PLAC8,PLCB1,PLSCR1,POMT1,POU3F3,PPARD,PRKCD,PRKD1,PRR16,PTPRC,PYM1,RAF1,RAMP1,RARG,RBMS3,RBPMS,REST,RFXANK,RORC,RXRA,SCAND1,SENP2,SERPINF2,SIX5,SMAD3,SMARCA2,SMARCD2,SOX12,SOX5,SPIN1,SSBP2,STAR,STAT3,STK16,TAL1,TBX18,TCEA2,TFEB,THRA,TLR1,TNNI2,TP53,TP63,TRERF1,TRIP11,USF2,USP22,VDR,WNT5A,YY2,ZBED3,ZBTB16,ZBTB7B,ZIC1,ZNF219,ZNF497,ZNF76,ZNF821 |
| GO_SKELETAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 526 | 65 | ADAMTS7,AXIN2,BGN,BMP1,BMP4,BMP5,CDKN1C,COL12A1,COL14A1,COL1A1,COL1A2,COL3A1,COL5A2,COL9A2,EFEMP1,EN1,ENG,EXTL1,EYA1,FGR,FMN1,GDF5,HOXA4,HOXA7,HYAL1,IFT140,INHA,INPPL1,ITGB8,MAPK3,MEGF8,MEIS1,MGP,MMP2,NDST1,NFIB,NOG,NPR3,OSR1,PDGFC,PKDCC,PLEKHA1,PLXNB1,PTPRC,RANBP3L,RARG,RSPO2,SLC35D1,SLC38A10,SMAD3,SOX5,SPARC,TAL1,TGFBI,THRA,TLE5,TLL1,TP53,TP63,TRIP11,VDR,WDR60,WNT5A,ZBTB16,ZNF219 |
| GO_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 634 | 72 | ABCA12,ABCA4,ABCA7,ABCC3,ABCD1,ACE2,AGT,ANO2,ANO8,APOC3,APOE,APOL1,ARL6IP5,ATP1A2,ATP8B4,BEST2,BEST4,CA12,CD36,CETP,CLCA2,CLCNKA,CLIC3,CPT2,EMB,FOLR1,FXYD3,KCNN4,KMO,MTTP,NMB,OSBPL5,OSR1,PDPN,PDZK1,PITPNM2,PLSCR1,PLSCR4,PPARD,PRKCD,RHAG,ROS1,RXRA,SCP2,SLC12A9,SLC13A4,SLC16A14,SLC16A7,SLC1A1,SLC20A2,SLC24A5,SLC25A1,SLC26A1,SLC26A2,SLC27A2,SLC27A4,SLC2A14,SLC2A8,SLC35D1,SLC37A2,SLC38A10,SLC4A2,SLC52A1,SLC7A7,SLC9A9,SLCO1B1,SLCO2A1,SLCO6A1,STRA6,SV2A,TNFAIP8L3,TRPC4 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1189 | 105 | ABCA7,ABL1,ADARB1,AGT,ANGPT1,ANXA8,ANXA8L1,APOE,BCOR,BEX3,BMP4,BTG2,C3,C4A,C4B,CAAP1,CABIN1,CALM3,CAPN3,CAV3,CDKN1C,CDKN2B,CHMP6,CR1,CRIM1,CTSZ,DAG1,DKK1,DUSP19,EIF2AK4,EIF4EBP2,ENG,EPHA1,F2RL1,FBLN1,FKBP8,FLOT2,GAS1,GMFB,GNAQ,GPER1,GPX1,GRB7,HEXIM1,HEXIM2,HFE,IGF1R,IGFBP5,IKBKB,INHA,INPP5D,INPP5J,ITIH3,KAT2B,KLF15,LAX1,LRRK2,MAP2K5,MECOM,MLLT1,NANOS1,NNT,NOG,NR2F2,PANO1,PAPLN,PBLD,PCIF1,PDCD4,PIAS3,PIK3R2,PIN1,PIP5KL1,PMEPA1,PPP1R35,PRKCD,PRMT6,PRR7,PSCA,PTPA,PTPN22,PTPRC,PURA,RAF1,SENP2,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SHMT1,SMAD3,SNX25,SOCS5,SPINK9,SSPO,STAT3,STYX,TP53,VIL1,VPS28,WFDC1,WFDC8,ZBED3,ZC3H12D |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1652 | 1174 | 104 | ABL1,ADARB1,AGT,AJUBA,ANXA8,ANXA8L1,AOC3,APOC3,APOE,ATP1A2,BEX3,BMP4,C3,C4A,C4B,CAAP1,CABIN1,CACNB3,CALCR,CALM3,CAV3,CDKN1C,CDKN2B,CHMP6,CNR1,CR1,CRIM1,CTSZ,CYP27B1,DKK1,DKK3,DKKL1,DUSP19,EFHB,EIF2AK4,EPHA1,ERBIN,FOXH1,FZD6,GCHFR,GMFB,GNAQ,GPX1,GSTM2,HECW2,HEXIM1,HEXIM2,HFE,IGF1R,IKBKB,ITIH3,KAT2B,KCNE3,KCNE4,LAX1,LEPR,LRRK2,LYNX1,LYPD1,MAP2K5,MAPK3,MLLT1,MSTN,NEIL1,NOG,NPR3,NR2F2,NWD1,OSR1,PAPLN,PARP3,PARP9,PCIF1,PDCD4,PDE6G,PIN1,PKD2,PKHD1,PLXNB3,PPP1R35,PRKCD,PTPA,PTPN22,PTPRC,RAF1,RIPOR2,RTKN,SENP2,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SOCS5,SPINK9,SSPO,STYX,TLE5,TP53,TRIM37,VIL1,WDR81,WFDC1,WFDC8 |
| GO_EMBRYONIC_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 592 | 69 | ABL1,APLN,AR,ATOH8,BMP4,BMP5,CCDC40,CDKN1C,CELSR1,CFL1,COL12A1,COL5A2,DAG1,DKK1,DLL1,EFEMP1,EN1,ENG,EXT2,EYA1,FLRT3,FOLR1,FOXH1,FZD6,GATA3,GDF5,HOXA4,HOXA7,HYAL1,IFT140,IRX3,ITGB4,LAMA3,LAMB1,MAFB,MAP2K5,MAPK3,MEGF8,MMP2,NDST1,NOG,OSR1,PHLDB1,PKD2,PLXNB2,POU3F4,RARG,RIPOR2,RSPO2,SHROOM3,SLITRK6,SMAD3,STOX1,STRA6,TAL1,TBC1D32,TBX18,TMEM107,TP53,TP63,TRIOBP,TSHZ1,TTC39C,VAX2,WDR60,WNT5A,ZBTB16,ZIC1,ZNF358 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1724 | 133 | ABCA7,ABL1,ACKR3,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,APOE,AR,AREL1,ARL6IP5,ASB9,ASPSCR1,AXIN2,AZU1,BAD,BEX3,BMP4,BMP5,BOK,C3,CALCR,CALM3,CAPN3,CAV3,CCBE1,CCND3,CCR7,CD33,CD36,CD4,CLEC3B,CR1,CTSH,DAG1,DBNL,DET1,DKK1,DOCK3,DUSP19,EFNA5,EIF2AK4,ENG,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGF7,FPR1,GATA3,GDF5,GPER1,GPR183,GPRC5C,GRM1,HECW2,HFE,HTR2C,IGF1R,IL27RA,IL6R,INHA,LAMTOR1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MSTN,MTCP1,NDST1,NEK10,NSMF,PAK3,PAK6,PARP9,PCIF1,PCOLCE,PCOLCE2,PDE6G,PDGFC,PDGFD,PIAS3,PIK3CB,PIK3R3,PIN1,PKD2,PLCB1,PLCE1,POMT1,PRKCD,PRKD1,PRR16,PRR7,PTPA,PTPN22,PTPRC,PYM1,RAF1,RAMP1,RAPGEF2,RARRES2,RBMS3,RBPMS,REST,RNF180,RXRA,SENP2,SERPINF2,SMAD3,SOCS5,ST20,STAT3,STOX1,STRADA,TAB1,TAL1,TLR1,TNFAIP8L3,TNFSF12,TNKS1BP1,TP53,TRABD2A,TRABD2B,VEGFB,VPS28,WNK3,WNT5A,ZBTB7B,ZYG11B |
| GO_LIPID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1652 | 241 | 43 | ABCD1,ACAD10,ACADL,ACADS,AGT,APOE,APPL2,AUH,B4GALNT2,BDH2,CERK,CISH,CNR1,CPT2,CYGB,CYP2E1,DECR2,DGKA,DGKB,ECHDC2,ECI2,ETFB,HADH,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IVD,LAMTOR1,MTMR4,PEX13,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PPARD,SCP2,SLC27A2,SOCS5,TTC7A |
| GO_BLOOD_VESSEL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 686 | 75 | ABL1,ACKR3,ADAM12,ADGRF5,ADGRG1,AGGF1,AGT,AMOTL2,ANGPT1,ANGPT2,ANGPT4,ANPEP,APLN,APOE,B4GALT1,BMP4,C3,CCBE1,COL15A1,COL18A1,COL3A1,COL8A2,CREB3L1,CTSH,DAG1,DLL1,EDNRA,ENG,EPHA1,ERBB2,EYA1,FOLR1,FOXH1,GPX1,GTF2I,HOXA7,HPGD,HPSE,HSPG2,HYAL1,ITGB8,JMJD8,LEPR,MAP2K5,MEIS1,MMP2,MYLK,MYO1E,NOG,NPR1,NR2F2,PIK3CB,PIK3R3,PKD2,PRKD1,PTPRB,RAMP1,RAPGEF2,RNF213,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SPARC,STARD13,STAT3,STIM1,STRA6,TAL1,TGFBI,TGFBR3,TIE1,TNFSF12,VEGFB,WNT5A |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 0.0e+00 | 1652 | 687 | 75 | AJUBA,AK3,AKAP1,ANXA8,APOE,AXL,B4GALT1,BLOC1S4,CAPN3,CAV3,CD36,CELSR1,COL1A1,COL1A2,COL3A1,DAG1,DGKA,DGKB,DOCK1,DOCK11,EHD2,ENO3,ERBB2,EVPLL,F2R,F2RL1,FBLN1,FGF7,FLRT3,FOLR1,FZD6,GATA3,GIP,GNA14,GNAQ,GPX1,H3-3A,H3C6,HPS6,HPSE,ITGB4,LAMB2,MAPK3,MMP12,MSTN,MYL9,MYLK,MYOF,NFE2,NOG,PDPN,PIK3CB,PIK3R1,PLSCR1,PPARD,PPL,PRKCD,RAF1,RTN4RL1,SCARF1,SELENON,SERPINA5,SERPINF2,SMAD3,SPAAR,SPARC,TLN1,TP53,TPM1,TSPAN8,TXN2,VIL1,VWF,WFDC1,WNT5A |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1146 | 102 | ABCA7,ABL1,ACKR3,ADCY6,ADGRF5,AGT,AJUBA,ANGPT1,ANGPT4,APLN,APOE,AR,ARL6IP5,AXIN2,AZU1,BAD,BMP4,BMP5,C3,CALCR,CALM3,CCND3,CCR7,CD33,CD36,CD4,DAG1,DBNL,DKK1,DOCK3,DUSP19,EFNA5,ENG,ENTPD5,ERBB2,ETAA1,F2R,F2RL1,FGF7,FGR,FPR1,GDF5,GPD1,GPER1,GPR183,GPRC5C,GRM1,HFE,HTR2C,IGF1R,IL27RA,IL6R,INHA,ITSN1,LAMTOR1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MSTN,MTCP1,NDST1,NEK10,NSMF,PAK3,PAK6,PARP9,PDE6G,PDGFC,PDGFD,PFKFB1,PIK3CB,PIK3R3,PIN1,PKD2,PLCB1,PLCE1,PRKCD,PRKD1,PTPA,PTPN22,PTPRC,RAF1,RAPGEF2,RARRES2,RBPMS,SENP2,SERPINF2,SMAD3,STAT3,STOX1,STRADA,TAB1,TAL1,TNFAIP8L3,TNKS1BP1,TP53,VEGFB,WNK3,WNT5A |
| GO_CELLULAR_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 963 | 91 | ABCA12,ABL1,ACKR3,AGT,ANK2,APOE,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BAD,BOK,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CKB,CNR1,CXCL12,CXCR5,DMPK,DNAJC16,EDNRA,EFNA5,EPHA5,F2R,F2RL1,FPR1,GPER1,GPX1,GRM1,GSTM2,GTF2I,HFE,HMGN3,HTR2C,IGF1R,JAGN1,JPH2,KCNN4,KLF15,LPAR2,LPAR6,LRRK2,MAPK3,MSTN,NEDD8,NMB,NNT,PDE6A,PIK3CB,PIK3R1,PIK3R2,PKD2,PKHD1,PLCB1,PLCD4,PLCE1,PLCH2,PTGER2,PTPRC,RAF1,RHAG,SELENON,SERPINF1,SIDT2,SLC12A9,SLC24A5,SLC4A2,SLC9A9,SMAD3,STAR,STIM1,SV2A,SYNPO,TMEM203,TNS2,TP53,TPCN2,TRPC4,TRPM2,TTC7A,TXN2,VDR,WNT5A |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 984 | 92 | ABCA12,ABCA7,ABL1,ACE2,ACTN4,AGT,ALOX15B,ANGPT1,ANK2,ANXA13,AP2A1,APLN,APOE,APPL2,AXL,AZU1,BAD,BOK,C3,C4A,C4B,CACNB3,CADM1,CADPS2,CALCR,CALM3,CAPN3,CASQ1,CAV3,CD33,CD36,CD4,CNR1,CTSS,CXCL12,DLL1,DNM1,EHD2,ERBB2,F2R,F2RL1,FGR,GATA3,GIP,GPER1,GSTM2,HFE,HSPA1L,IL17RC,INHA,ITSN1,JPH2,KCNE3,KCNN4,KLF15,KMO,LRRK2,MAPK3,MAVS,MMP12,MYLK,MYO18A,MYOM1,NLGN3,NMB,NPR1,OR51E2,ORM1,PDZK1,PIK3R1,PIK3R2,PKD2,PPARD,PRKCD,PTPN22,PTPRC,SCP2,SEC16A,SMAD3,STAC2,STIM1,STIMATE,TBC1D5,TLR1,TP53,TP63,TRIM46,VAMP8,VPS28,WNK3,WNT5A,ZIC1 |
| GO_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 831 | 83 | ABCD1,ABL1,ACKR3,AGT,ANK2,APOE,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BDH2,BOK,CA12,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CETP,CKB,CNR1,CXCL12,CXCR5,CYP27B1,DMPK,EDNRA,F2R,F2RL1,FPR1,GPAM,GPER1,GRM1,GSTM2,GTF2I,HFE,HSH2D,HTR2C,JPH2,KLHL3,LPAR2,LPAR6,LRRK2,MAPK3,NEDD8,NMB,NPR1,PDE6A,PIK3CB,PKD2,PKHD1,PLCB1,PLCD4,PLCE1,PLCH2,PTGER2,PTPRC,RHAG,SCN2B,SCNN1B,SELENON,SLC12A9,SLC24A5,SLC4A2,SLC9A9,SMAD3,STEAP3,STIM1,SV2A,SYNPO,TMEM203,TP53,TPCN2,TRPC4,TRPM2,TTC7A,VDR,WNK3,WNT5A |
| GO_GROWTH | 0.0e+00 | 0.0e+00 | 1652 | 990 | 92 | ABL1,ADARB1,AGT,ALOX15B,APBB2,APOE,AR,ATRN,BCAR1,BMP4,CAPN3,CAV3,CDKL5,CDKN1C,CISH,COL12A1,COL14A1,CXCL12,CYP27B1,DAG1,DBNL,DLL1,EFNA5,EIF2AK4,EN1,ENO3,ERBB2,FGF7,FKBP8,FLRT3,FMN1,GAS1,GATA3,GDF5,GPAM,GPX1,H3-3A,HYAL1,IGFBP5,KAZALD1,KLHL22,LAMB2,LAMTOR1,LEPR,MAP2K5,MEGF8,MEIS1,MSTN,NANOS1,NLGN3,NOG,NPR1,OPA3,PIN1,PKDCC,PLAC8,PLCB1,PLCE1,PLEKHA1,PPARD,PPP1R13L,PYGO2,RARG,ROS1,RSPO2,RXRA,SELENON,SELENOP,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLITRK6,SMAD3,SMARCA2,SOCS5,SPAAR,SPG11,SPTBN2,ST20,STAT3,STRA6,TGFBR3,TLE5,TNS2,TP53,TRIM46,TSPYL2,ULK2,VIL1,WFDC1,WNT5A |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 1235 | 105 | ABCA4,ACOT11,ACTN4,ADA,AGT,AJUBA,ALDH3A1,ANGPT2,ANGPT4,APPL2,ASCL1,ATP1A2,BACE1,BAD,BTG2,C9orf116,CACNB3,CAPN3,CASQ1,CAV3,CIAO3,CNN2,CNTNAP2,COL18A1,COL1A1,COL3A1,CRIP1,CTSS,CXCL12,CYGB,DAG1,DNMT3A,DPP4,EDNRA,EFHD1,EIF2AK4,ENG,ERCC5,EYA1,FMO1,FUNDC1,GATA3,GDF5,GIP,GNAQ,GPX1,GRM1,GTF2H5,HSPA1L,HYAL1,INTS3,KCNJ3,KMO,KRT14,MAPK3,MB,MC1R,MME,MMP2,MMP7,MSTN,MYD88,MYLK,MYOF,NLGN3,NPHP1,NR2F6,NSMF,OPN3,PDE6A,PDE6G,PDLIM1,PIK3R1,PIN1,PKD2,PLAC8,PPARD,PPL,PPP1CB,PSEN2,PTPRC,RAF1,RCSD1,REST,RIPOR2,SCN1A,SERPINF1,SLC2A8,SLITRK6,SMAD3,SPARC,ST20,STAR,STOX1,STRA6,SYNPO,TGFBR3,THRA,TMC1,TNKS1BP1,TP53,TRPM2,TXN2,UCP2,VEGFB |
| GO_WOUND_HEALING | 0.0e+00 | 0.0e+00 | 1652 | 572 | 66 | AJUBA,AK3,AKAP1,ANXA8,APOE,AXL,B4GALT1,BLOC1S4,CAPN3,CAV3,CD36,CELSR1,COL1A1,COL1A2,COL3A1,DAG1,DGKA,DGKB,DOCK1,DOCK11,EHD2,ENO3,ERBB2,EVPLL,F2R,F2RL1,FBLN1,FZD6,GATA3,GNA14,GNAQ,GPX1,H3-3A,H3C6,HPS6,HPSE,MAPK3,MMP12,MSTN,MYL9,MYLK,MYOF,NFE2,NOG,PDPN,PIK3CB,PIK3R1,PLSCR1,PPARD,PPL,PRKCD,RAF1,SELENON,SERPINA5,SERPINF2,SMAD3,SPAAR,SPARC,TLN1,TP53,TPM1,TSPAN8,VIL1,VWF,WFDC1,WNT5A |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1652 | 1930 | 140 | ABCA12,ABCA7,ACOT2,AGT,AJUBA,ANGPT1,ANK2,ANXA13,AP2A1,APOE,APPL2,AR,ARF3,ARF5,ARL13A,ASPSCR1,AXIN2,BAD,BMP4,CACNB3,CACNG8,CALM3,CAPN3,CAV3,CD36,CD4,CELSR1,CNTNAP1,CNTNAP2,COL1A1,COPZ2,CPE,DAG1,DDO,DECR2,DNAJC15,DNM1,ECI2,EHD2,ERBB2,ERBIN,FAM53A,FGF7,FLOT2,FRMD6,GDAP1,GNAI1,GPER1,GPM6B,HERC2,HFE,HPS6,HSPA1L,ICK,IFT140,IKBKB,IQSEC2,ITSN1,KCNIP3,LAMTOR1,LRRK2,LYPD1,MAVS,MIOS,MMP12,NACC2,NUDCD3,OBSL1,PACS1,PARP3,PARP9,PDZK1,PEX13,PIK3R1,PIK3R2,PIN1,PKDCC,PLEKHF1,PPIL2,PRKCD,PTPRU,PURA,RAB11FIP3,RABL2A,RABL2B,RAMP1,RANBP3L,RAPGEF2,RASSF9,RBM15B,RIPOR2,RTKN,RTP4,SCP2,SEC16A,SLC27A2,SMAD3,STAC2,STAT3,STRADA,STX10,STYX,SUN2,SYNE2,SYTL1,TASOR,TAX1BP3,TBC1D2B,TBC1D32,TBC1D5,TBC1D9,TLN1,TMEM107,TMEM129,TMSB15B,TOM1L2,TP53,TP63,TRIM29,TRIM46,TRIP11,TTC30B,TTC7A,UBXN2B,VAMP8,VIL1,VPS13A,VPS13C,VPS28,VPS37D,VPS39,VPS41,WDR60,WNK3,WNT5A,ZBTB16,ZBTB7A,ZDHHC12,ZDHHC21,ZIC1 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 942 | 88 | ABL1,ACE2,ACTR3B,ADGRL3,AGT,AJUBA,APOE,ARPC5,ARPIN,BHLHB9,CAV3,CCDC151,CCR7,CD36,CDKL5,CLDN7,CUX2,DAG1,DBNL,DKK1,DLG5,DNAJC15,DOCK11,EFNA5,EPHA1,ERCC5,F2RL1,FHOD1,FHOD3,FLRT3,FMN1,FSCN1,GMFB,GPM6B,GTF2H5,H3-3A,HYAL1,IFT140,IKBKB,IL1RAPL2,INPP5J,JCHAIN,KAT2B,KLHL41,LMOD1,LRRC24,LRRK2,MSTN,NLGN3,NPHP1,PAK3,PAN2,PHLDB1,PIK3R1,PIP4K2B,PLD1,PLXNB3,PMEPA1,PRKCD,RAF1,RAPGEF2,REST,RIPOR2,SEMA4A,SEPTIN8,SERPINF2,SLITRK6,SMAD3,SNCAIP,SPTBN2,SYNE2,SYNPO,TAL1,TENM2,THRA,TMOD1,TMSB15B,TP53,TPM1,TRABD2A,TRABD2B,TRIM37,TRIOBP,TRPM2,VIL1,VILL,VPS41,WNT5A |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1870 | 137 | ABL1,ACTA2,ACTN1,ACTN4,AGT,APLN,APOE,AR,ARID4A,ASCL1,ATAD2B,ATOH8,BMP4,BMP5,BTG2,CAPN3,CARF,CD4,CDKN1C,CDKN2B,COL1A1,CREB3L1,DLL1,DPF3,EBF1,EHF,EN1,ENG,ENTPD5,ERBB2,EYA1,F2R,F2RL1,FGF7,FHOD1,FOXD3,FOXH1,GATA3,GLIS1,GPD1,GPER1,HMGN3,HOXA4,HOXA7,HOXC13,IKBKB,KAT2B,KDM8,KLF15,LHX8,LPIN3,MAFB,MAP2K5,MAP3K12,MAPK3,MAVS,MC1R,MECOM,MEIS1,METTL23,MITF,MLIP,MMP12,MSTN,NANOS1,NAT14,NFE2,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,OSR1,PADI2,PAK3,PARP3,PARP9,PDLIM1,PFKFB1,PIK3R1,PIK3R2,PIN1,PKD2,PLAC8,PLCB1,PLSCR1,POU3F3,PPARD,PRKCD,PRKD1,PTPRC,RAF1,RARG,RBPMS,REST,RFXANK,RORC,RXRA,SCAND1,SENP2,SERPINF2,SIX5,SMAD3,SMARCA2,SMARCD2,SOX12,SOX5,SPIN1,SSBP2,ST20,STAT3,STK16,TAL1,TBX18,TCEA2,TFEB,THRA,TNNI2,TP53,TP63,TRERF1,TRIP11,USF2,USP22,VDR,WNT5A,YY2,ZBED3,ZBTB16,ZBTB7B,ZC3H12D,ZIC1,ZNF219,ZNF497,ZNF76,ZNF821 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1710 | 129 | ABL1,ACTA2,ACTN1,ACTN4,AGT,APLN,APOE,AR,ARID4A,ASCL1,ATAD2B,ATOH8,BMP4,BMP5,BTG2,CAPN3,CARF,CD4,CDKN1C,CDKN2B,COL1A1,CREB3L1,DLL1,DPF3,EBF1,EHF,EN1,ENG,ERBB2,EYA1,F2R,F2RL1,FGF7,FHOD1,FOXD3,FOXH1,GATA3,GLIS1,GPER1,HMGN3,HOXA4,HOXA7,HOXC13,IKBKB,KAT2B,KDM8,KLF15,LHX8,LPIN3,MAFB,MAP2K5,MAP3K12,MAPK3,MAVS,MC1R,MECOM,MEIS1,METTL23,MITF,MLIP,MMP12,MSTN,NANOS1,NAT14,NFE2,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,OSR1,PADI2,PARP9,PDLIM1,PIK3R1,PIK3R2,PIN1,PKD2,PLAC8,PLCB1,PLSCR1,POU3F3,PPARD,PRKD1,RAF1,RARG,RBPMS,REST,RFXANK,RORC,RXRA,SCAND1,SENP2,SERPINF2,SIX5,SMAD3,SMARCA2,SMARCD2,SOX12,SOX5,SPIN1,SSBP2,STAT3,STK16,TAL1,TBX18,TCEA2,TFEB,THRA,TNNI2,TP53,TP63,TRERF1,TRIP11,USF2,USP22,VDR,WNT5A,YY2,ZBED3,ZBTB16,ZBTB7B,ZC3H12D,ZIC1,ZNF219,ZNF497,ZNF76,ZNF821 |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 1160 | 100 | ABCD1,ABL1,ACTN4,AGT,ANK2,ANO2,ANO8,APOL1,ARL6IP5,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BEST2,BEST4,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CLCA2,CLCNKA,CLIC3,CNGB3,CPT2,CTSS,DMAC2L,EMB,F2R,FOLR1,FXYD3,GPER1,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,NALCN,NIPAL2,NLGN3,NNT,OSR1,PDPN,PDZK1,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,RAF1,RHAG,SCN1A,SCN2B,SCNN1B,SELENON,SLC12A9,SLC13A4,SLC15A2,SLC16A7,SLC1A1,SLC20A2,SLC22A5,SLC24A5,SLC25A1,SLC26A1,SLC26A2,SLC2A8,SLC35D1,SLC37A2,SLC38A10,SLC41A3,SLC4A2,SLC7A7,SLC9A9,STAC2,STEAP3,STIM1,STIMATE,STRA6,TMC1,TMEM63A,TPCN2,TRPC4,TRPM2,UCP2,UTRN,WNK3 |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 1000 | 91 | ABL1,ADA,AGT,ALOX15B,AP2A1,APOE,AR,ASCL1,ATOH8,AXIN2,AXL,BAD,BHLHB9,BLOC1S5,BMP4,BMP5,BRINP3,CAV3,CD36,CD4,CDKL5,CNR1,COL1A1,CUX2,CXCL12,CYP27B1,DAG1,DBNL,DKK1,DKKL1,DLG5,DOCK1,EFNA5,EHD2,ENG,FAIM,FAM210B,GATA3,GDF5,GPER1,HTR2C,IL6R,INPP5D,IRX3,ITSN1,LIMS2,MEGF8,MME,NCKIPSD,NSMF,OBSL1,PAK3,PDE3A,PDPN,PIN1,PKDCC,PLAAT4,PLCB1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPARD,PPP1R13L,PRKD1,PTPRC,RAC3,RANBP3L,RAPGEF2,RARRES2,REST,RIPOR2,SCARF1,SEMA3C,SERPINF1,SERPINF2,SMAD3,SOCS5,SOX5,STAR,STAT3,SULT1E1,TAL1,TP63,TRIOBP,VDR,WASHC5,WNT5A,ZBTB16,ZBTB7B,ZNF219 |
| GO_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 695 | 73 | ABL1,ACTN4,ADA,ADGRG1,ANGPT1,ANGPT2,AZU1,B4GALNT2,BAD,BMP4,CCDC80,CCL28,CCR7,CD36,CD4,CLDN7,COL1A1,CTLA4,CXCL12,CYTIP,DAG1,DLG5,DLL1,DOCK1,DPP4,EFNA5,EGFL6,EPHA1,ERBB2,FBLN1,FBLN2,FLOT2,FMN1,GATA3,GPAM,GPM6B,HFE,HOXA7,HYAL1,LAMA3,LAX1,LIMS2,LOXL3,MAP2K5,MMP12,PAK3,PDPN,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPP1CB,PRKCD,PTPN22,PTPRC,PTPRO,PTPRU,RAC3,RIPOR2,RNASE10,SEMA3E,SERPINF2,SMAD3,SOCS5,TGFBI,TPM1,TRIOBP,UTRN,WNT5A,ZBTB16,ZBTB7B |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1652 | 1135 | 98 | ABL1,ADA,ADCY6,ADGRL3,AGT,ALDH3A1,APOE,APPL2,ASCL1,ATP6V0A4,BACE1,BAD,BCAR1,BTG2,CALCR,CALM3,CAV3,CCND3,CCR7,CD36,CFL1,CNR1,COL1A1,COL1A2,COL3A1,COL5A2,CXCL12,CYP2E1,DAG1,DNM1,DNMT3A,EDEM3,EIF4EBP2,ERBIN,FCSK,FFAR3,FOLR1,FUNDC1,GIP,GNA14,GNAI1,GNAQ,GPD1,GPER1,GSTM2,HADH,HTR2C,IGF1R,IGFBP5,INPPL1,KAT2B,KLF15,KLHL22,LAMTOR1,LDOC1,LPIN3,LRRK2,LYPD1,MAPK3,MARC2,MAVS,MGST2,MMP12,MMP2,MSTN,MYD88,NCOA5,NSMF,P2RY11,PDE3A,PDGFC,PDGFD,PFKFB1,PIK3R1,PIK3R2,PIK3R3,PKD2,PLCB1,PRKCD,PTPN22,PTPRA,RAPGEF2,RARRES2,RECQL5,SELENON,SESN1,SHMT1,SLC2A8,SOCS5,SPAAR,SPARC,STAR,STAT3,TGFBR3,TMEM129,TP53,TRPM2,ZBTB7B |
| GO_EPITHELIAL_CELL_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1652 | 441 | 56 | AGGF1,APLN,APOE,AR,ATOH8,B4GALT1,BAD,BMP4,BMP5,CDKN1C,CDKN2B,COL8A2,CXCL12,CYP7B1,EHF,ERBB2,ESRP2,EYA1,FGF7,GATA3,GDF5,GPX1,HYAL1,IGFBP5,LAMB1,LIMS2,MAP2K5,MCC,MMP12,NFIB,NOG,NR2F2,OR51E2,OSR1,PBLD,PIK3CB,PLXNB3,PPARD,PRKD1,PURA,PYGO2,SERPINF1,SGPP2,SIDT2,SMAD3,SPARC,STAT3,STOX1,TGFBR3,TGM1,TNFSF12,TP63,VDR,VEGFB,WFDC1,WNT5A |
| GO_UROGENITAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 331 | 48 | ACTA2,AGT,ALOX15B,ANGPT1,ANGPT2,AR,BMP4,CDKN1C,CRIP1,CTSH,CYP7B1,DLG5,DLL1,EYA1,FMN1,GATA3,HPGD,IFT140,IL6R,IRX3,ITGB4,KANK2,KLF15,KLHL3,LAMB2,LRRK2,MME,MYO1E,NFIA,NOG,OSR1,PDGFD,PKD2,PKHD1,PLCE1,POU3F3,PTPRO,PYGO2,RARG,RXRA,SERPINF1,SMAD3,STRA6,TBX18,TNS2,TP63,WNT5A,ZBTB16 |
| GO_IMMUNE_EFFECTOR_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1267 | 105 | ABL1,ACLY,ACTR1B,ADA,ADARB1,AGBL4,AGBL5,AGL,ALDH3B1,ANGPT1,ANPEP,APOBEC3C,APOBEC3G,APPL2,ARPC5,ARSA,ASAH1,ATP8B4,AZU1,B4GALT1,BTN3A3,C1R,C1RL,C3,C4A,C4B,CADM1,CD33,CD36,CFB,CNN2,CPPED1,CR1,CRISP3,CRISPLD2,CRP,CTSH,CTSS,CTSZ,CUEDC2,CYBC1,DBNL,DLL1,DOCK1,DOCK11,EIF2AK4,F2RL1,FCGR2A,FFAR3,FGR,FPR1,GATA3,GPAM,GPR183,HFE,HGSNAT,HPSE,IFITM2,IFITM3,IGHV3-73,IL1R1,IL27RA,INPP5D,JAGN1,LAMTOR1,LOXL3,MAPK3,MAVS,METTL7A,MME,MMP12,MMP25,MYO18A,NCKIPSD,NFAM1,NLRX1,OLR1,ORM1,PADI2,PARP3,PARP9,PIK3CB,PIK3R1,PIK3R2,PLAC8,PLD1,PLSCR1,PPM1B,PRKCD,PTPRB,PTPRC,RORC,RTP4,SEMA4A,SERPINA3,SLC27A2,SOCS5,STAT3,TMEM63A,TP53,TRIM22,TRPM2,VAMP8,WNT5A,ZBTB7B |
| GO_HEAD_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 774 | 77 | ABL1,ADGRG1,ADGRL3,AFF2,ARMC4,ARPC5,ASCL1,ATRN,AXL,BAD,BMP4,BMP5,BOK,BTG2,CALM3,CKB,CNTNAP2,COL1A1,COL3A1,CRISPLD2,CTTNBP2,CXCL12,DKK1,DLG5,DLL1,EDNRA,EN1,EPHA5,FLRT3,FZD6,H3-3A,HSPG2,ITSN1,KLHL1,LAMB1,LHX8,LIMK2,LRRK2,MAFB,MAPK3,MMP2,NANOS1,NDST1,NFIB,NOG,NR2F2,PADI2,PEX13,PLCB1,PLEKHA1,PLXNB2,POU3F3,POU3F4,PYGO2,RAC3,RAF1,RAPGEF2,RARG,RTN4RL1,SEC16A,SELENOP,SHROOM4,SPTBN2,STAR,STK36,STRA6,SUN2,SYNE2,THRA,TP53,TRABD2A,TSKU,VAX2,VCX,WNT5A,ZDHHC16,ZIC1 |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 847 | 81 | ABL1,ADA,ADGRL3,AJUBA,B4GALNT2,BAD,BLOC1S4,BMP4,BMP5,CADM1,CADM3,CCL28,CCR7,CD33,CD4,CDH6,CEL,CELSR1,CELSR3,CLDN7,COL14A1,COL8A2,CTLA4,CTNNA3,CXCL12,DLG5,DPP4,EFNA5,EMB,ERBB2,FAT2,FLOT2,FLRT3,GATA3,GLDN,GPAM,HFE,LAMA3,LAMB1,LAX1,LIMS2,LOXL3,MAP2K5,MYL9,NLGN3,NPHP1,PAK3,PCDH15,PCDH9,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PCDHB8,PCDHGA2,PCDHGB6,PCDHGC3,PDLIM1,PDPN,PIK3CB,PIK3R1,PKHD1,PLEKHA7,PLXNB2,PLXNB3,PRKCD,PTPN22,PTPRC,PTPRU,RIPOR2,RNASE10,SCARF2,SERPINF2,SOCS5,TENM2,TLN1,TRIM29,VSTM2L,WNT5A,ZBTB16,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 750 | 75 | ACTN4,ADAMTS7,ADCY6,ADGRG1,ANKRD2,APOE,APPL2,ASCL1,AXIN2,BMP4,BMP5,CAV3,CETP,COL3A1,COL5A2,CRP,CTLA4,CTSZ,DGUOK,DKK1,DLL1,EFEMP1,EFNA5,EIF2AK4,ERBB2,FBLN1,GATA3,GDF5,GLIS1,GPER1,HOPX,HOXA7,IGFBP5,INHA,INPP5D,INPP5J,IRX3,LOXL3,LRRK2,MAFB,MEIS1,MSTN,NLGN3,NOG,OSR1,PBLD,PDCD4,PIAS3,PIK3R1,PLPP7,PPARD,PTPRO,RANBP3L,RAPGEF2,RARG,REST,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SOCS5,STAT3,TAL1,TOB2,TP53,TP63,TRIM46,TRIO,TWIST2,ULK2,WNT5A,ZBTB16,ZBTB7B |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1652 | 604 | 66 | ABL1,ACKR3,ACTN4,AGT,ANGPT1,ANGPT4,ATOH8,AZU1,BCAR1,BMP4,CCBE1,CCR7,CD99L2,CLDN7,COL18A1,COL1A1,CTSH,CXCL12,DEFB1,DOCK1,EPHA1,F2R,F2RL1,FGF7,FGR,GATA3,GPER1,GRB7,HYAL1,IGF1R,IGFBP5,IL1R1,IL6R,LAMB1,MAPK3,MEGF8,MSTN,MYLK,NSMF,PAK3,PDGFC,PDGFD,PDPN,PIK3R1,PIK3R3,PRKD1,PTPRC,RAPGEF2,RARRES2,RIPOR2,RNASE10,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SPARC,STAT3,SUN2,SYNE2,TMSB15B,TP53,TWIST2,VEGFB,VIL1,WNT5A |
| GO_TAXIS | 0.0e+00 | 0.0e+00 | 1652 | 652 | 69 | ACKR3,ANGPT1,ANGPT2,APBB2,AZU1,BCAR1,BMP4,CCL28,CCR7,CELSR3,CHN1,CXCL12,CXCR5,CYP7B1,DAG1,DEFB1,DOK1,EFNA5,EMB,EPHA1,EPHA5,ERBB2,F2RL1,FGF7,FLRT3,FPR1,GATA3,GFRA1,GPR183,GRB7,HSD3B7,IL17RC,IL6R,LAMB2,LYPLA2,MAPK3,MEGF8,MMP28,MSTN,NFIB,NOG,NTN4,PADI2,PDGFD,PIK3CB,PIK3R1,PLD1,PLEKHG5,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKCD,PRKD1,PTPRA,PTPRO,RARRES2,RIPOR2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SPTBN2,TRIO,TRPM2,VEGFB,VSTM2L,WNT5A |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 669 | 70 | ABL1,ACTN1,ACTN4,ACTR3B,ADAMTS2,APOE,ARPC5,ARPIN,BCAR1,CAPN3,CASQ1,CAV3,CCR7,CD36,CFL1,COL12A1,COL14A1,COL1A1,COL1A2,COL3A1,COL5A2,CORO6,CORO7,CXCL12,DBNL,EFEMP2,EFS,EPHA1,F2RL1,FHOD1,FHOD3,FMN1,FSCN1,GMFB,GPX1,HOOK2,INPP5J,INPPL1,KLHL41,KRT14,LDB3,LIMA1,LMOD1,LOXL3,MSRB1,MSRB2,MYOM1,MYOM3,NAA80,NEBL,OBSL1,PAK3,PIK3R1,PRKCD,RAC3,RHOBTB2,SERPINF2,SHROOM3,SHROOM4,SMAD3,SPTBN2,SYNPO,TCHH,TMOD1,TMSB15B,TPM1,TPM4,TRIOBP,VIL1,VILL |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 976 | 88 | ABL1,ADARB1,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,APOE,AZU1,BAD,BMP4,CALM3,CAV3,CCND3,CCR7,CD4,CDKN1C,CDKN2B,CHMP6,CISH,DAG1,DBNL,DKK1,DOCK3,DUSP19,EFNA5,EPHA1,ERBB2,ETAA1,F2R,FGR,FPR1,GMFB,GNAQ,GPRC5C,GRM1,HEXIM1,HEXIM2,IGF1R,IL6R,ITSN1,JMJD8,KAT2B,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MLLT1,MSTN,MTCP1,NEK10,NR2F2,PAK3,PAK6,PARP3,PARP4,PDCD4,PDE6G,PDGFC,PDGFD,PFKFB1,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIN1,PKD2,PLAAT4,PLCE1,PRKCD,PRKD1,PTPN22,PTPRC,RAF1,RAPGEF2,RBL2,SOCS5,STOX1,STRADA,TAB1,TAL1,TNFAIP8L3,TP53,TSPYL2,WDR81,WNT5A |
| GO_TISSUE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 670 | 70 | ABL1,ACTA2,ACTG2,ADARB1,AGT,AJUBA,AP2A1,AR,BMP4,BMP5,CAV3,CCDC40,CELSR1,CELSR3,CFL1,COL12A1,COL14A1,COL3A1,CTSH,CTSZ,CYP7B1,DAG1,DKK1,DLG5,DLL1,EDNRA,ENG,ESRP2,EXT2,EYA1,FGF7,FLRT3,FMN1,FOLR1,FOXH1,FZD6,GATA3,IGFBP5,IRX3,ITGB4,KLHL3,LAMA3,MEGF8,MMP12,MYLK,MYOM1,MYOM3,NOG,NTN4,OSR1,PDPN,PKD2,PLXNB2,RARG,RSPO2,RXRA,SEMA3C,SEMA3E,SHROOM3,SMAD3,STARD13,STOX1,TAL1,TBX18,TGFBR3,TNNC1,TP63,TPM1,VDR,WNT5A |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 995 | 89 | ABL1,ADARB1,ADGRG1,ADGRL3,AFF2,ARMC4,ARPC5,ASCL1,ATRN,AXL,B4GALT6,BAD,BMP4,BMP5,BOK,BTG2,C3,CALM3,CELSR1,CKB,CNTNAP1,CNTNAP2,COL3A1,CTTNBP2,CXCL12,DAG1,DKK1,DLG5,DLL1,EN1,ENG,EPHA5,ERBB2,FZD6,H3-3A,HSPG2,IL1RAPL2,ITSN1,KLHL1,LAMB1,LAMB2,LHX8,LOXL3,LRRK2,MAFB,MAPK3,NANOS1,NAV2,NDST1,NFIB,NLGN3,NOG,NR2F2,PADI2,PDGFC,PEX13,PKD2,PLCB1,PLXNB2,POU3F3,POU3F4,POU6F2,PYGO2,RAC3,RAPGEF2,RCAN1,RTN4RL1,SEC16A,SELENOP,SHROOM4,SOX12,SPTBN2,STAR,STAT3,STK36,SUN2,SYNE2,TAL1,THRA,TP53,TRIO,TRPC4,TSKU,VAX2,VCX,WNT5A,ZBTB16,ZDHHC16,ZIC1 |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 872 | 82 | ABL1,ADARB1,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,APOE,AZU1,BAD,BMP4,CALM3,CAV3,CCND3,CCR7,CD4,CDKN1C,CDKN2B,CHMP6,CISH,DAG1,DBNL,DKK1,DOCK3,DUSP19,EFNA5,EPHA1,ERBB2,ETAA1,F2R,FGR,FPR1,GMFB,GNAQ,GPRC5C,GRM1,HEXIM1,HEXIM2,IGF1R,IL6R,ITSN1,KAT2B,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MLLT1,MSTN,MTCP1,NEK10,NR2F2,PAK3,PAK6,PDCD4,PDE6G,PDGFC,PDGFD,PFKFB1,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PKD2,PLCE1,PRKCD,PRKD1,PTPN22,PTPRC,RAF1,RAPGEF2,RBL2,SOCS5,STOX1,STRADA,TAB1,TAL1,TNFAIP8L3,TSPYL2,WDR81,WNT5A |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 372 | 50 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADI1,ADO,ANGPT1,B4GALT1,B4GALT6,BGN,CBR4,CHST14,CHST9,CIAO3,DBI,ELOVL3,ELOVL5,GPAM,GPX1,GSTA1,GSTA2,GSTM2,GSTT2B,HACD1,HACD2,HS3ST3B1,HYAL1,MCCC1,MGST2,NDST1,NDST4,NUBPL,PDP2,SLC25A1,SLC26A1,SLC26A2,SLC35D1,ST3GAL3,ST3GAL6,SUCLG2,SULT1A1,SULT1B1,SULT1E1,TKTL1,TPK1,TXN2 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1280 | 104 | AJUBA,ANKRD2,AR,ARID4A,ASCL1,ATAD2B,ATOH8,BCOR,BEND5,BMP4,BTG2,CAPN3,CC2D1B,CCND3,CD36,CDKN1C,CIPC,CREB3L1,CUX2,CXXC5,DACH1,DKK1,DKK3,DNMT3A,DPF3,EID1,EID2,EN1,FOXD3,FOXH1,GATA3,GLIS1,H3-3A,H3C6,HEXIM1,HEXIM2,HOXA7,KANK2,KCNIP3,KCTD1,KDM8,LOXL3,MAP2K5,MECOM,MITF,MLIP,MMP12,NACC2,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,NR2F6,OSR1,PARP9,PDCD4,PIAS3,PLCB1,POU3F3,PPARD,PPP1R13L,PRMT6,PURA,RARG,RECQL5,REST,RORC,RXRA,SIX5,SMAD3,SMARCA2,SOX5,STAT3,TAL1,TASOR,TBX18,TCEAL1,TENM2,THRA,TLE2,TLE5,TOB2,TP53,TP63,TRIM22,TRIM29,TRIM37,TWIST2,VAX2,VDR,WNT5A,ZBTB16,ZBTB37,ZBTB7A,ZBTB7B,ZC3H4,ZHX1,ZNF217,ZNF219,ZNF366,ZNF497,ZNF776 |
| GO_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1652 | 1457 | 113 | ADA,ADAM21,ADAMTS2,ADGRG1,ADGRG2,AGT,ALOX15B,ANGPT2,APOL2,AR,ARID4A,ATP1A4,AXL,B4GALT1,BAD,BMP4,BMP5,BOK,C9orf24,CADM1,CCDC40,CCDC87,CDKN1C,CNR1,COL9A3,CRIP1,CYP17A1,CYP27B1,CYP7B1,DACH1,DDO,DEFB1,DKKL1,DNMT3A,FBLN1,GATA3,GIP,GLIPR1L1,H3-3A,HERC2,HFE,HPGD,HSPA1L,IGFBP5,IGSF8,INHA,ITGB8,KLHL10,LDOC1,LEPR,LHX8,LIMK2,LNPEP,LRRK2,MAPK3,MME,MMP2,MMP7,MSTN,NOG,NPHP1,NR2F2,OSR1,PDE3A,PKD2,PLB1,PLCB1,PLCD4,PLEKHA1,PPARD,PSG1,PSG3,PYGO2,RARG,RLN1,RNASE10,ROS1,RXRA,SELENOP,SENP2,SERPINA5,SERPINF1,SIX5,SLC2A14,SLC2A8,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,SPIN1,SPIN2B,STAR,STAT3,STRA6,STS,SUN2,TDRD9,TFEB,THRA,TMEM203,TOB2,TP63,TSNAXIP1,TSPAN8,TUT4,VCX,VDR,WASHC5,WDR66,WNT5A,ZBTB16,ZNF541 |
| GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1652 | 763 | 75 | ADARB1,ADGRG1,ALOX15B,APLN,APOE,APPL2,AR,ATOH8,AXIN2,B4GALT1,BMP4,BMP5,BTG2,CD33,CDKN1C,CDKN2B,COL18A1,CTLA4,CYP27B1,DACH1,DLG5,DLL1,ERBB2,F2R,FBLN1,GATA3,GDF5,GPER1,IGFBP5,INPP5D,INPPL1,KANK2,KAT2B,LDOC1,LIMS2,MCC,MEIS1,MSTN,NACC2,NFIB,NOG,NPR1,NPR3,NR2F2,P3H2,PBLD,PBRM1,PDCD4,PDPN,PKD2,PLAAT4,PLXNB1,PPARD,PTPRU,RAF1,RAPGEF2,RARG,REST,SERPINF1,SIX5,SMAD3,SMARCA2,SPARC,STAT3,TAX1BP3,TGFBR3,TNS2,TOB2,TP53,TPM1,VDR,WFDC1,WNT5A,ZBTB16,ZBTB7B |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1247 | 102 | ABCA7,ABL1,ACKR3,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,APOE,AR,ARL6IP5,ASPSCR1,AXIN2,AZU1,BMP4,BMP5,C3,CALCR,CALM3,CCND3,CCR7,CD33,CD36,CD4,DAG1,DBNL,DKK1,DOCK3,DUSP19,EFNA5,ENG,ERBB2,ETAA1,F2R,F2RL1,FGF7,FPR1,GATA3,GDF5,GPER1,GPR183,GPRC5C,GRM1,HFE,HTR2C,IGF1R,IL27RA,IL6R,INHA,LAMTOR1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MAVS,MSTN,MTCP1,NDST1,NEK10,NSMF,PAK3,PAK6,PARP9,PDE6G,PDGFC,PDGFD,PIAS3,PIK3CB,PIK3R3,PIN1,PKD2,PLCB1,PLCE1,POMT1,PRKCD,PRKD1,PTPA,PTPN22,PTPRC,RAF1,RAMP1,RAPGEF2,RARRES2,RBPMS,RNF180,SENP2,SERPINF2,STAT3,STOX1,STRADA,TAB1,TAL1,TNFAIP8L3,TNKS1BP1,TP53,TRABD2A,TRABD2B,VEGFB,WNK3,WNT5A,ZBTB7B |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 1287 | 104 | ABL1,AGFG2,AGT,AJUBA,ANXA8,ANXA8L1,APOC3,ARL6IP5,BAD,BEX3,BOK,C3,C4A,C4B,CAAP1,CABIN1,CALM3,CCR7,CD33,CDKL5,CHN1,CR1,CRIM1,CTSH,DMPK,DNAJC15,DOCK1,DOCK11,EDNRA,EFNA5,EPHA1,EPHA5,ERBB2,F2R,F2RL1,FBLN1,FGD3,FGD4,GCHFR,GNAQ,GPER1,GPX1,IKBKB,ITIH3,LEPR,LPAR2,LRRK2,MAP2K5,MAPK3,MTSS2,NEIL1,PAPLN,PCIF1,PCOLCE,PCOLCE2,PCSK6,PIN1,PLCB1,PLEKHG6,PLSCR1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PPP1R35,PPP6R2,PRKCD,PRKD1,PRR7,PTPA,PTPRC,RAF1,RANBP3L,RAPGEF2,RCAN1,RCAN3,REST,RIN2,RTKN,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SMAD3,SPINK9,SSPO,ST20,STARD13,STAT3,TAX1BP3,TBC1D2B,TBC1D5,TBC1D9,TNNC1,TP53,TP63,TPM1,VIL1,WDR60,WDR81,WFDC1,WFDC8,WNT5A |
| GO_RESPONSE_TO_GROWTH_FACTOR | 0.0e+00 | 0.0e+00 | 1652 | 732 | 73 | ABL1,ADAMTS7,AGT,ANGPT2,APLN,APPL2,ASCL1,BCAR1,BMP4,CAV3,CCBE1,CDKN1C,CDKN2B,CLEC3B,COL1A1,COL1A2,COL3A1,CREB3L1,DAND5,DKK1,DKK3,DLL1,EID2,ENG,ERBB2,ESRP2,FBXL15,FGF7,FKBP8,FLRT3,FOLR1,FOXH1,FSTL1,GAS1,GATA3,GDF5,HFE,HPGD,HYAL1,MAP2K5,MAPK3,MEGF8,MSTN,MTMR4,MTSS2,MYOF,NDST1,NOG,PBLD,PCSK6,PDCD4,PDE3A,PDGFD,PIN1,PMEPA1,POLR2L,PRKD1,RAF1,RAPGEF2,RASL11B,SMAD3,SNX25,SOX5,SPARC,STAR,STK16,TAB1,TGFBR3,TP53,VEGFB,VIL1,WNT5A,ZBTB7A |
| GO_ALCOHOL_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 377 | 50 | ACADL,ACLY,ALDH3B1,APOE,APOL1,APOL2,ASAH1,BMP5,CBR4,CEL,CETP,CYP27B1,CYP7B1,DKK3,GPAM,GPD1,GPER1,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,LEPR,LIMA1,MYOF,NUDT3,OSBPL5,PLB1,PLCB1,PLCD4,PLCE1,PLCH2,PLD4,PPARD,RDH11,RDH14,REST,RXRA,SCARF1,SGPP2,SLC5A3,STAR,SULT1A1,SULT1B1,SULT1E1,TRERF1,TTC39B,VDR |
| GO_RESPONSE_TO_HORMONE | 0.0e+00 | 0.0e+00 | 1652 | 994 | 88 | ADCY6,AGL,AGT,ALDH3A1,APPL2,AR,ATP1A2,ATP6V0A4,BAD,BCAR1,BMP4,BTG2,CALCR,CALM3,CCND3,CCR7,CD4,COL1A1,CTSH,CTSS,CXCL12,CYP7B1,DAG1,DNMT3A,EFNA5,EIF4EBP2,ENG,FAM210B,FFAR3,FOXH1,GIP,GNAI1,GNAQ,GPAM,GPER1,H3-3A,HADH,HPGD,IGF1R,IGFBP5,INPPL1,KANK2,KAT2B,KLF15,LEPR,LPIN3,LYPD1,MB,MSTN,NCOA5,NR2F2,NR2F6,NSMF,OR51E2,PADI2,PFKFB1,PIAS3,PIK3R1,PIK3R2,PIK3R3,PLCB1,PMEPA1,PPARD,PRKCD,PTGER2,PTPRA,PTPRU,RAMP1,RARG,RARRES2,REST,RORC,RXFP1,RXRA,SERPINF1,SLC2A8,SPARC,STAR,STAT3,TGFBR3,THRA,TP63,TXN2,VDR,WFDC1,ZBTB7A,ZBTB7B,ZNF366 |
| GO_MUSCLE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 470 | 56 | ACE2,ACTA2,ACTG2,ADA,AGT,ANK2,ANKRD2,ATP1A2,CALM3,CASQ1,CAV3,CCDC78,CTNNA3,DAG1,DMPK,EDNRA,F2R,GPER1,GSTM2,GTF2IRD1,GTF2IRD2,IGFBP5,KCNE3,KCNE4,KCNJ3,KLF15,KLHL41,LMOD1,MB,MLIP,MSTN,MTMR4,MYL9,MYLK,MYOF,MYOM1,MYOM3,PIN1,PLCE1,PPP1R13L,RCSD1,SCN1A,SCN2B,SELENON,SMAD3,SNTB1,STAC2,TLN1,TMOD1,TNNC1,TNNI2,TPCN2,TPM1,TPM4,UTRN,VEGFB |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 627 | 66 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADA,ADCY6,AGPAT1,AGPAT4,AK1,AK3,APOBEC3C,APOBEC3G,B4GALNT2,BAD,CBR4,CTPS2,DBI,DGUOK,DMAC2L,DPYD,DPYS,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD4,ENTPD5,FCSK,GPAM,GPD1,GPX1,HACD1,HACD2,JMJD8,KMO,LRRK2,NEIL1,NME3,NME4,NPR1,NUDT12,NUDT13,NUDT3,PANK1,PARP9,PDE1A,PDE7B,PDE8B,PDP2,PFKFB1,SHMT1,SLC25A1,SLC26A1,SLC26A2,SLC35D1,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,TK2,ZBTB7A |
| GO_SYNAPSE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 414 | 52 | ABL1,ACTN1,ADGRL3,APOE,BHLHB9,C3,CACNB3,CDKL5,CEL,CFL1,COL4A5,CTTNBP2,CUX2,DAG1,DBNL,DGKB,DKK1,DLG5,DMPK,EFNA5,ERBB2,F2R,FLRT3,IGF1R,IL1RAPL2,ITSN1,LAMB2,LRRC24,LRRK2,NFIA,NLGN3,PAK3,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PCDHGC3,PIN1,PLXNB1,PLXNB2,PTPRO,REST,SEMA3E,SEMA4A,SEPTIN11,SLITRK6,SPARC,SPTBN2,SYNPO,UNC13C,UTRN,WNT5A |
| GO_CELLULAR_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 683 | 69 | ABL1,ACKR3,AGT,ANK2,APOE,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BOK,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CKB,CNR1,CXCL12,CXCR5,DMPK,EDNRA,F2R,F2RL1,FPR1,GPER1,GRM1,GSTM2,GTF2I,HFE,HTR2C,JPH2,LPAR2,LPAR6,LRRK2,MAPK3,NEDD8,NMB,PDE6A,PIK3CB,PKD2,PKHD1,PLCB1,PLCD4,PLCE1,PLCH2,PTGER2,PTPRC,RHAG,SELENON,SLC24A5,SLC4A2,SLC9A9,SMAD3,STIM1,SV2A,SYNPO,TMEM203,TP53,TPCN2,TRPC4,TRPM2,TTC7A,VDR,WNT5A |
| GO_METAL_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 667 | 68 | ABL1,ACKR3,AGT,ANK2,APOE,ATP13A1,ATP1A2,ATP1A4,BDH2,BOK,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CNR1,CXCL12,CXCR5,CYP27B1,DMPK,EDNRA,F2R,F2RL1,FPR1,GPER1,GRM1,GSTM2,GTF2I,HFE,HTR2C,JPH2,LPAR2,LPAR6,NEDD8,NMB,NPR1,PDE6A,PIK3CB,PKD2,PKHD1,PLCB1,PLCD4,PLCE1,PLCH2,PTGER2,PTPRC,RHAG,SCNN1B,SELENON,SLC12A9,SLC24A5,SMAD3,STEAP3,STIM1,SV2A,SYNPO,TMEM203,TPCN2,TRPC4,TRPM2,TTC7A,VDR,WNT5A |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1470 | 112 | AJUBA,ANGEL2,ANKRD2,AR,ARID4A,ASCL1,ATAD2B,ATOH8,AXIN2,BCOR,BEND5,BMP4,BTG2,CAPN3,CC2D1B,CCND3,CD36,CDKN1C,CIPC,CREB3L1,CUX2,CXXC5,DACH1,DKK1,DKK3,DNMT3A,DPF3,EID1,EID2,EN1,FOXD3,FOXH1,GATA3,GLIS1,GPER1,H3-3A,H3C6,HEXIM1,HEXIM2,HOXA7,KANK2,KCNIP3,KCTD1,KDM8,LOXL3,MAP2K5,MECOM,MITF,MLIP,MMP12,MYD88,NACC2,NEIL1,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,NR2F6,NUDT16L1,OSR1,PARP3,PARP9,PDCD4,PFKFB1,PIAS3,PLCB1,POU3F3,PPARD,PPP1R13L,PRMT6,PURA,RARG,RECQL5,REST,RORC,RXRA,SIX5,SMAD3,SMARCA2,SOX5,STAT3,TAL1,TASOR,TBX18,TCEAL1,TENM2,THRA,TLE2,TLE5,TOB2,TP53,TP63,TRIM22,TRIM29,TRIM37,TWIST2,VAX2,VDR,WNT5A,ZBTB16,ZBTB37,ZBTB7A,ZBTB7B,ZC3H4,ZHX1,ZNF217,ZNF219,ZNF366,ZNF497,ZNF776 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 592 | 63 | ABL1,ADARB1,APBB2,APOE,B4GALT6,BHLHB9,C8orf37,CDKL5,CELSR3,CFL1,CHN1,CUX2,CXCL12,DAG1,DBNL,DOK1,EFNA5,EMB,EPHA1,EPHA5,ERBB2,FLRT3,GATA3,GFRA1,GRB7,HECW2,LAMB2,LRRK2,LYPLA2,MAPK3,MEGF8,NFIB,NLGN3,NOG,NSMF,NTN4,OBSL1,PAK3,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRA,PTPRO,RAPGEF2,RIPOR2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLITRK6,SPG11,SPTBN2,TRIM46,TRIO,TRIOBP,TSKU,ULK2,VAX2,VSTM2L,WNT5A |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1652 | 1765 | 126 | ABCD1,ACE2,ACKR1,ADA,ADARB1,AGBL4,AGBL5,AGT,AOC3,APOBEC3C,APOBEC3G,APOE,APOL1,APOL2,APOL3,APPL2,ATRN,AXL,AZU1,B4GALT1,C1R,C1RL,C3,C4A,C4B,CADM1,CCR7,CD36,CD4,CERS6,CFB,CNR1,CR1,CRISP3,CRP,CTSS,CUEDC2,CXCL12,CYBC1,CYP27B1,DEFB1,DPP4,EIF2AK4,ERBIN,F2R,F2RL1,FBXO9,FFAR3,FGR,FPR1,GATA3,GPAM,GPER1,GPX1,HEXIM1,HFE,HSPG2,HTR2C,HYAL1,IFITM2,IFITM3,IGHV3-73,IKBKB,IKBKE,IL17RC,IL17RE,IL1R1,IL27RA,IL6R,JAGN1,JCHAIN,KCNN4,LOXL3,LRRK2,LYPD1,LYPD8,MAPK3,MAVS,MGST2,MMP12,MMP25,MR1,MSRB1,MUC15,MYD88,NDST1,NFAM1,NLRX1,OLR1,ORM1,P2RY11,PAK3,PARP4,PARP9,PDCD4,PLAC8,PLSCR1,PPARD,PPM1B,PRKCD,PRKD1,PSG3,PTGER2,PTPN22,PTPRC,RAF1,RARRES2,RBMS3,RTP4,SERPINA3,SERPINF1,SERPINF2,SMAD3,SOCS5,SSC5D,STAR,STAT3,TAB1,TLR1,TP53,TRIM22,TRIM29,TRIM59,VAMP8,WFDC1,WNT5A |
| GO_NEGATIVE_REGULATION_OF_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1652 | 396 | 50 | ADA,ADARB1,ADGRG1,ALOX15B,ANGPT2,ANGPT4,APOE,ARPIN,BMP5,CCL28,COL3A1,CXCL12,CYGB,DACH1,DAG1,DLG5,ENG,EPHA1,FBLN1,GATA3,GCSAM,HOXA7,IGFBP5,IL27RA,MAP2K5,MCC,MITF,MMP28,NOG,NR2F2,PADI2,PBLD,PIN1,PIP5KL1,PLCB1,PLXNB3,PPARD,PTPRO,PTPRU,RIPOR2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,STARD13,STAT3,TIE1,TPM1,WNT5A |
| GO_DEVELOPMENTAL_GROWTH | 0.0e+00 | 0.0e+00 | 1652 | 677 | 68 | ABL1,ADARB1,AGT,APOE,AR,ATRN,BMP4,CAPN3,CAV3,CDKL5,CDKN1C,COL12A1,COL14A1,CXCL12,DAG1,DBNL,DLL1,EFNA5,EIF2AK4,EN1,ENO3,FGF7,FKBP8,FLRT3,FMN1,GAS1,GATA3,GDF5,GPAM,GPX1,H3-3A,LAMB2,LEPR,MEGF8,MEIS1,MSTN,NLGN3,NOG,PIN1,PKDCC,PLAC8,PLCB1,PLEKHA1,PPARD,PPP1R13L,PYGO2,RARG,RSPO2,RXRA,SELENON,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLITRK6,SMAD3,SPAAR,SPG11,SPTBN2,STAT3,STRA6,TGFBR3,TNS2,TP53,TRIM46,ULK2,VIL1,WNT5A |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 955 | 84 | ABL1,ACTN4,ADCY6,ADGRG1,AGT,AP2A1,APOE,APPL2,ASCL1,AXIN2,BAD,BHLHB9,BMP4,BMP5,BRINP3,CAV3,CDKL5,CFL1,CHN1,CNR1,COL3A1,CSMD3,CTSZ,CUX2,CXCL12,DAG1,DBNL,DGUOK,DKK1,DLG5,DLL1,DOCK1,EFNA5,EIF2AK4,EYA1,FAIM,FBLN1,GATA3,GDF5,GPER1,GPR183,HECW2,IKBKB,INPP5J,IRX3,ITSN1,LIMS2,LRRK2,MEGF8,MEIS1,MME,NCKIPSD,NLGN3,NOG,NSMF,OBSL1,PAK3,PDE3A,PDPN,PIN1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRO,RAC3,RAPGEF2,REST,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,STAR,STAT3,TP53,TRIM46,TRIOBP,ULK2,WASHC5,WNT5A |
| GO_GLYCOPROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 412 | 51 | ABCA7,ALG6,ALG9,B3GALT4,B3GLCT,B3GNT10,B4GALNT2,B4GALT1,B4GALT6,BGN,CCR7,CHST14,CHST9,DOLK,DPM3,DPY19L4,EDEM3,ENTPD5,EXT2,EXTL1,FUT11,GALNT5,HPSE,HS3ST3B1,HS6ST3,HYAL1,MAN2B2,MGAT4B,MGAT4C,MMP12,MUC15,NDST1,NDST4,NECAB1,PCSK6,PLCB1,POMT1,PPARD,RAMP1,SGSH,SLC35D1,ST3GAL3,ST3GAL6,ST6GALNAC2,ST6GALNAC5,ST6GALNAC6,TMTC1,TMTC4,TRIP11,VEGFB,XXYLT1 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 0.0e+00 | 0.0e+00 | 1652 | 503 | 57 | ABL1,ACE2,ACTA2,ACTR3B,ADCY6,AGT,APLN,APOE,ARPC5,ARPIN,ATP1A2,CAV3,CCR7,CDKL5,CFL1,CRP,CXCL12,DBNL,EDNRA,EFNA5,F2R,F2RL1,FHOD3,FMN1,GMFB,GPER1,GPX1,KCNN4,LIMA1,LMOD1,LRRK2,MEGF8,NAA80,NPR1,PAK3,PEX11A,PEX11B,PEX11G,PPARD,PRKCD,PRR16,RARG,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF2,SLC12A9,SPTBN2,TMOD1,TMSB15B,TRIM46,TRIOBP,ULK2,VIL1,VILL,WNT5A |
| GO_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 1180 | 96 | ABL1,ACE2,ACTN4,ADA,AGT,ANK2,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CD33,CD4,CNGB3,CNR1,CTSS,CXCL12,CYP27B1,DMAC2L,DMPK,EFHB,F2R,FXYD3,GPER1,GPM6B,GRAMD2A,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,KLHL3,MYLK,NALCN,NIPAL2,NLGN3,NNT,OSR1,PDZK1,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,RAMP1,RHAG,SCN1A,SCN2B,SCNN1B,SELENON,SLC12A9,SLC13A4,SLC15A2,SLC1A1,SLC20A2,SLC22A5,SLC24A5,SLC2A8,SLC38A10,SLC41A3,SLC5A2,SLC5A3,SLC9A9,STAC2,STEAP3,STIM1,STIMATE,SYT12,TCN2,TMC1,TMEM63A,TPCN2,TRPC4,TRPM2,UCP2,UTRN,VAMP8,VDR,WNK3 |
| GO_SECOND_MESSENGER_MEDIATED_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 443 | 53 | ACKR3,ADA,ADCY6,ADGRG1,ADGRG2,ADGRL3,AGT,ANK2,APOE,ATP1A2,AZU1,CALCR,CALM3,CASQ1,CCR7,CD36,CD4,CXCR5,DEFB1,DMPK,EFHB,EIF4EBP2,EPHA5,FPR1,GIP,GNAI1,GNAQ,GPER1,GSTM2,HTR2C,INPP5A,JPH2,LRRK2,MC1R,MGRN1,NPR1,OR51E2,P2RY11,PDE3A,PKD2,PLCE1,PTGER2,PTPRC,RAMP1,RAPGEF2,RCAN1,RCAN3,RXFP1,SELENON,STIMATE,TMBIM4,TPCN2,TRPM2 |
| GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 414 | 51 | ABCD1,ACADL,ADGRF5,AGT,APOC3,APOE,APPL2,ASAH1,BMP5,C3,CCR7,CD36,CISH,CNR1,CPT2,CYP27B1,DKK3,DKKL1,DNAJC15,ELOVL5,FGR,GIP,GPAM,GPER1,HTR2C,LAMTOR1,LGALS12,LPGAT1,MTMR4,OPA3,PDP2,PEX11A,PIK3R1,PIK3R2,PIK3R3,PPARD,PRKCD,PRKD1,RARRES2,RBL2,REST,RORC,RXRA,SERPINA3,SOCS5,STAR,THRA,TNFAIP8L3,TTC39B,VDR,WDR81 |
| GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 387 | 49 | ABL1,ABRACL,ACTR3B,ANK2,ARPC5,ARPIN,ATP1A2,CAV3,CCR7,CELSR1,CFL1,CNN2,CTNNA3,CXCL12,DBNL,EFNA5,EPHA1,EPHA5,F2RL1,FHOD1,FHOD3,FMN1,FRMD6,FSCN1,GMFB,GPM6B,KCNE3,LIMA1,LMOD1,NAA80,PAK3,PDPN,PIK3R1,PRKCD,RAC3,RHOBTB2,SEMA3E,SERPINF2,SMAD3,SPTBN2,SYNPO,TMOD1,TMSB15B,TNNC1,TPM1,TRIOBP,TRPM2,VIL1,VILL |
| GO_ORGANIC_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 492 | 56 | ABCA12,ABCA4,ABCA7,ABCC3,ABCD1,ACE2,AGT,APOC3,APOE,ARL6IP5,ATP1A2,ATP8B4,CA12,CD36,CETP,CPT2,EMB,FOLR1,KCNN4,KMO,MTTP,NMB,OSBPL5,PDPN,PITPNM2,PLSCR1,PLSCR4,PPARD,PRKCD,RHAG,RXRA,SCP2,SLC13A4,SLC16A14,SLC16A7,SLC1A1,SLC25A1,SLC26A1,SLC26A2,SLC27A2,SLC27A4,SLC2A14,SLC2A8,SLC35D1,SLC37A2,SLC38A10,SLC4A2,SLC52A1,SLC7A7,SLCO1B1,SLCO2A1,SLCO6A1,STRA6,SV2A,TNFAIP8L3,TRPC4 |
| GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 525 | 58 | ABL1,ACKR3,AGT,ANK2,APOE,ATP13A1,ATP1A2,BOK,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CNR1,CXCL12,CXCR5,CYP27B1,DMPK,EDNRA,F2R,F2RL1,FPR1,GPER1,GRM1,GSTM2,GTF2I,HTR2C,JPH2,LPAR2,LPAR6,NMB,PDE6A,PIK3CB,PKD2,PKHD1,PLCB1,PLCD4,PLCE1,PLCH2,PTGER2,PTPRC,SELENON,SLC24A5,SMAD3,STIM1,SV2A,SYNPO,TMEM203,TPCN2,TRPC4,TRPM2,VDR,WNT5A |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1652 | 860 | 78 | AJUBA,ANKRD2,AR,ASCL1,BCOR,BMP4,BTG2,CC2D1B,CCND3,CD36,CDKN1C,CREB3L1,CUX2,CXXC5,DACH1,DKK1,DNMT3A,EID1,EID2,EN1,FOXD3,FOXH1,GATA3,GLIS1,HEXIM1,HEXIM2,HOXA7,KANK2,KCNIP3,KCTD1,MAP2K5,MITF,MLIP,MMP12,NACC2,NFIA,NFIB,NFIC,NFIX,NOG,NR2F2,NR2F6,OSR1,PARP9,PIAS3,PPARD,PPP1R13L,PRMT6,PURA,RARG,RECQL5,REST,RORC,RXRA,SMAD3,SMARCA2,STAT3,TAL1,TBX18,TCEAL1,TENM2,THRA,TLE5,TP53,TP63,TRIM29,TRIM37,VAX2,VDR,ZBTB16,ZBTB37,ZBTB7A,ZBTB7B,ZHX1,ZNF217,ZNF219,ZNF366,ZNF497 |
| GO_CELL_SUBSTRATE_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 348 | 46 | ABL1,ACTN1,ACTN4,AJUBA,AKIP1,ANGPT1,ANGPT2,AXL,CCDC80,CCL28,CCR7,CD36,COL1A1,COL3A1,DAG1,DOCK1,EFNA5,EGFL6,EPHA1,FAT2,FBLN1,FBLN2,FMN1,GPM6B,HOXA7,HPSE,ITGA11,ITGB4,LAMB1,LAMB2,LIMS2,MMP12,MSLN,NTN4,PARVB,PDPN,PIK3CB,PIK3R1,PPARD,PTPRO,RAC3,SEMA3E,SMAD3,TRIOBP,UTRN,VWF |
| GO_CELL_PART_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 691 | 68 | ABL1,ADARB1,APBB2,APOE,ARPIN,B4GALT6,BHLHB9,CDKL5,CELSR3,CFL1,CHN1,CNTNAP1,CNTNAP2,CUX2,CXCL12,DAG1,DBNL,DOK1,EFNA5,EIF2AK4,EMB,EPHA1,EPHA5,ERBB2,FLRT3,GATA3,GFRA1,GRB7,HECW2,LAMB2,LRRK2,LYPLA2,MAPK3,MEGF8,NFIB,NLGN3,NOG,NSMF,NTN4,NUBPL,OBSL1,OPA3,PAK3,PDPN,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRA,PTPRO,RAPGEF2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLITRK6,SPG11,SPTBN2,TRIM46,TRIO,TSKU,ULK2,VAX2,VIL1,VSTM2L,WNT5A |
| GO_ACTIN_FILAMENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 393 | 49 | ABL1,ACTN1,ACTN4,ACTR3B,ARPC5,ARPIN,BCAR1,CAV3,CCR7,CFL1,CORO6,CORO7,CXCL12,DBNL,EFS,EPHA1,F2RL1,FHOD1,FHOD3,FMN1,FSCN1,GMFB,INPPL1,LIMA1,LMOD1,MSRB1,MSRB2,MYOM1,MYOM3,NAA80,NEBL,PAK3,PIK3R1,PRKCD,RAC3,RHOBTB2,SERPINF2,SHROOM3,SHROOM4,SMAD3,SPTBN2,SYNPO,TMOD1,TMSB15B,TPM1,TPM4,TRIOBP,VIL1,VILL |
| GO_ORGANIC_ACID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 271 | 40 | AASS,ABCD1,ACAD10,ACADL,ACADS,ACSF3,ADO,ALDH1L1,AUH,BDH2,CEL,CNR1,CPT2,DBT,DDO,DECR2,ECHDC2,ECI2,ETFB,GPT,HADH,HOGA1,HPD,HYAL1,IDNK,IVD,KMO,KYAT1,LDHD,LPIN3,MCCC1,PEX13,PPARD,PRODH,SARDH,SCP2,SHMT1,SLC27A2,SLC27A4,TXN2 |
| GO_OSSIFICATION | 0.0e+00 | 0.0e+00 | 1652 | 396 | 49 | ATP6V0A4,AXIN2,BCOR,BMP1,BMP4,BMP5,CLEC3B,COL1A1,COL1A2,COL5A2,CREB3L1,CYP27B1,DKK1,EXT2,FBXL15,FGR,GDF5,GLIS1,GPM6B,H3-3A,IGFBP5,IL6R,INPPL1,ITGA11,KAZALD1,MAPK3,MGP,MMP2,MN1,MRC2,NOG,OSR1,PKDCC,PLXNB1,PRKD1,RANBP3L,RDH14,REST,RSPO2,SLC26A2,SMAD3,SPARC,THRA,TOB2,TP63,TPM4,TWIST2,WNT5A,ZBTB16 |
| GO_REGULATION_OF_BODY_FLUID_LEVELS | 0.0e+00 | 0.0e+00 | 1652 | 506 | 56 | ABCA12,ADA,ADCY6,AK3,AKAP1,ANXA8,APLN,APOE,AXL,BLOC1S4,CD36,CEL,COL1A1,COL1A2,COL3A1,DGKA,DGKB,DOCK1,DOCK11,EHD2,F2R,F2RL1,FBLN1,FZD6,GATA3,GNA14,GNAQ,H3-3A,H3C6,HPS6,HPSE,KCNN4,MAPK3,MYL9,NFE2,NPR1,NPR3,PDPN,PIK3CB,PIK3R1,PLSCR1,PRKCD,PTPRO,RAF1,SCNN1B,SERPINA5,SERPINF2,TLN1,TP63,TSPAN8,USF2,VAMP8,VDR,VWF,WNK3,ZBTB7B |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 860 | 77 | ABL1,ACTN4,ANK2,ANO2,ANO8,APOL1,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,BEST2,BEST4,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CLCA2,CLCNKA,CLIC3,DMAC2L,F2R,FXYD3,GPER1,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,NALCN,NIPAL2,NNT,OSR1,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,SCN1A,SCN2B,SCNN1B,SELENON,SLC12A9,SLC13A4,SLC15A2,SLC1A1,SLC20A2,SLC24A5,SLC26A1,SLC26A2,SLC2A8,SLC37A2,SLC9A9,STAC2,STEAP3,STIM1,STIMATE,TMC1,TPCN2,TRPC4,TRPM2,UCP2,UTRN,WNK3 |
| GO_PATTERN_SPECIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 446 | 52 | ADGRG1,AR,ARMC4,ASCL1,AXIN2,BCOR,BMP4,BMP5,BTG2,C3,C9orf116,CCDC151,CCDC40,CELSR1,DAND5,DKK1,DLL1,EN1,ENG,EYA1,FBXL15,FKBP8,FOLR1,FOXH1,HOXA4,HOXA7,HOXC13,IFT140,IRX3,MAFB,MEGF8,NEK8,NOG,NR2F2,OSR1,PCSK6,PKD2,RARG,SEMA3C,SENP2,SHROOM3,SMAD3,TBC1D32,TBX18,TMEM107,TP53,TP63,TSHZ1,VAX2,WNT5A,ZBTB16,ZIC1 |
| GO_PHOSPHATIDYLINOSITOL_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 177 | 32 | ARF3,CISH,DPM3,HTR2C,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,LPGAT1,MPPE1,MTMR4,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,PITPNM2,PITPNM3,PLCB1,PLCD4,PLCH2,PLEKHA1,RUFY1,SOCS5,TTC7A |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 1429 | 107 | ABL1,ADCY6,AGFG2,AGT,AJUBA,ANGPT1,ANGPT4,APOE,ARL6IP5,AZU1,BAD,BEX3,BMP4,BOK,CALM3,CCND3,CCR7,CD33,CD4,CDKL5,CHN1,CR1,CTSH,CYP27B1,DAG1,DBNL,DKK1,DNAJC15,DOCK1,DOCK11,DOCK3,DUSP19,EDNRA,EFNA5,EPHA1,ERBB2,ETAA1,F2R,F2RL1,FBLN1,FGR,FPR1,GMFB,GNAQ,GPER1,GPRC5C,GRM1,IL6R,ITSN1,LPAR2,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MGST2,MTCP1,MTSS2,NEK10,NPR3,PAK3,PAK6,PCOLCE,PCOLCE2,PDE6G,PDGFC,PDGFD,PDP2,PFKFB1,PIK3CB,PIN1,PKD2,PLAAT4,PLCB1,PLCE1,PLEKHG6,PLSCR1,PLXNB1,PRKCD,PRKD1,PRR7,PSEN2,PTPA,PTPRC,RAF1,RANBP3L,RAPGEF2,REST,RIN2,SMAD3,ST20,STARD13,STAT3,STIM1,STOX1,STRADA,TAB1,TAL1,TAX1BP3,TBC1D2B,TBC1D5,TBC1D9,TNFAIP8L3,TPM1,VDR,WDR60,WNT5A |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1652 | 973 | 83 | ABL1,ADA,ADCY6,ADGRL3,AGL,AGT,ALDH3A1,ANGPT2,AR,ASCL1,ATP1A2,BAD,BMP4,BTG2,CALCR,CALM3,CD36,CD4,CNR1,COL1A1,CYP27B1,CYP7B1,DAG1,DNMT3A,EFNA5,ENG,FAM210B,FCSK,FOLR1,FOXH1,GDAP1,GIP,GNA14,GNAI1,GNAQ,GPAM,GPD1,GPER1,GSTM2,HPGD,HTR2C,IGFBP5,KANK2,LRRK2,LY6D,MAPK3,MAVS,MSTN,NEDD8,NR2F2,NR2F6,OR51E2,P2RY11,PADI2,PAK3,PDE3A,PFKFB1,PKD2,PMEPA1,PPARD,PTGER2,PTPRU,RAPGEF2,RARG,RECQL5,REST,RORC,RXRA,SELENON,SERPINF1,SHMT1,SPARC,STAR,STAT3,THRA,TP53,TP63,TRPM2,TXN2,VDR,WFDC1,ZBTB7A,ZNF366 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1652 | 1782 | 124 | AASS,ABCA7,ABL1,ACADL,ACTR3B,AJUBA,ALDH9A1,ANGPT1,ANGPT4,APOC3,APOE,APPL2,ARMC4,ARPC5,ARPIN,AXIN2,B4GALT1,BAD,BMP1,BOK,C9orf24,CABIN1,CADPS2,CAPN3,CASQ1,CAV3,CBR4,CCDC151,CCDC40,CCR7,CD36,CHMP6,CLDN7,COA5,COL1A2,CORO7,CTSZ,CXCL12,DBNL,DET1,DKK1,DLG5,DMAC1,DNAJC15,DPYS,EFNA5,EID2,ERCC5,FHOD3,FMN1,FOLR1,FSCN1,GCHFR,GMFB,GTF2H5,H3-3A,H3C6,HFE,HGSNAT,HOPX,IGF1R,IKBKE,INPP5J,JCHAIN,KCTD1,KCTD12,KCTD19,LMOD1,LRRK2,MAPK3,MITF,MSRB1,MSRB2,MTTP,MYOM1,MYOM3,NACC2,NDUFV2,NUBPL,PAK3,PDGFC,PEX11B,PKD2,PLEKHA7,PMEPA1,POGZ,PRKCD,PYGO2,RABGGTA,RAF1,RIPOR2,RNF213,SEC16A,SEPTIN11,SEPTIN8,SHMT1,SLC1A1,SLC9A3R2,SMAD3,SOX12,SPTBN2,SV2A,TAL1,TGFBR3,THRA,TLE2,TLN1,TMOD1,TMSB15B,TP53,TP63,TRABD2A,TRABD2B,TRAPPC2L,TRIM22,TRIOBP,TRPM2,TSPYL2,TSPYL4,UNC13C,VIL1,VILL,VPS41,VWF |
| GO_RENAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 294 | 41 | ACTA2,AGT,ANGPT1,ANGPT2,BMP4,CDKN1C,CTSH,DLG5,DLL1,EYA1,FMN1,GATA3,HPGD,IFT140,IL6R,IRX3,ITGB4,KANK2,KLF15,KLHL3,LAMB2,LRRK2,MME,MYO1E,NFIA,NOG,OSR1,PDGFD,PKD2,PKHD1,PLCE1,POU3F3,PTPRO,PYGO2,SERPINF1,SMAD3,STRA6,TBX18,TNS2,WNT5A,ZBTB16 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 1267 | 98 | ABL1,ACTR3B,ANAPC11,ARPC5,ARPIN,ATAD2B,AXIN2,BAD,BCOR,BMP4,BOK,CAV3,CCDC151,CCR7,CDKL5,CDKN1C,CELSR1,CEP70,CFL1,CUL9,CXCL12,DBNL,EFNA5,EID1,EPHA1,EPHA5,F2RL1,FHOD1,FHOD3,FMN1,FSCN1,GATA3,GMFB,GNAI1,GPER1,GPM6B,GPX1,H3-3A,HECW2,HSPA1L,IFT140,INF2,INPP5J,KAT2B,KLHL22,LIMA1,LMOD1,LRRK2,MAPK3,MAVS,NAA80,OBSL1,OMA1,PADI2,PAK3,PAN2,PARP3,PDE3A,PHLDB1,PIK3R1,PIN1,PIP4K2B,PKHD1,PLCB1,PLXNB1,PRKCD,PRKD1,PRMT6,PYGO2,RAC3,RASSF7,RHOBTB2,SEMA3E,SEPTIN8,SERPINF2,SMAD3,SPTBN2,STOX1,SYNE2,SYNPO,TAL1,TASOR,TMOD1,TMSB15B,TOM1L2,TP53,TP63,TPM1,TRIM37,TRIOBP,TRPM2,UBXN2B,VIL1,VILL,VPS13C,VPS41,WNT5A,ZBTB7B |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 687 | 66 | ABL1,ADCY6,AGT,AP2A1,APOE,ARPIN,BHLHB9,BMP5,CCDC151,CCR7,CDKL5,CFL1,CHN1,CNR1,CSMD3,CTSZ,CUX2,CXCL12,DBNL,DGUOK,DKK1,DLG5,DOCK11,EFNA5,F2RL1,FSCN1,GATA3,HECW2,IFT140,INPP5J,ITSN1,KLHL41,LRRK2,MEGF8,MSTN,NCKIPSD,NLGN3,NSMF,OBSL1,PAK3,PDPN,PLD1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKCD,PRKD1,PTPRO,RAPGEF2,RIPOR2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SYNE2,TENM2,TRIM46,TRPM2,ULK2,VIL1,WASHC5,WNT5A |
| GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 0.0e+00 | 0.0e+00 | 1652 | 369 | 46 | ABL1,ACKR3,AGT,ANK2,ATP1A2,BOK,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCL28,CCR7,CD36,CD4,CNR1,CXCR5,EDNRA,F2R,F2RL1,FPR1,GPER1,GRM1,GSTM2,GTF2I,HTR2C,JPH2,LPAR2,LPAR6,NMB,PDE6A,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PTGER2,PTPRC,SELENON,SMAD3,SYNPO,TPCN2,TRPC4,TRPM2,WNT5A |
| GO_GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 341 | 44 | ABCA7,ALG6,ALG9,B3GALT4,B3GLCT,B3GNT10,B4GALNT2,B4GALT1,B4GALT6,BGN,CCR7,CHST14,CHST9,DOLK,DPM3,DPY19L4,EDEM3,ENTPD5,EXT2,EXTL1,FUT11,GALNT5,HS3ST3B1,HS6ST3,MGAT4B,MGAT4C,MUC15,NDST1,NDST4,NECAB1,PLCB1,POMT1,RAMP1,SLC35D1,ST3GAL3,ST3GAL6,ST6GALNAC2,ST6GALNAC5,ST6GALNAC6,TMTC1,TMTC4,TRIP11,VEGFB,XXYLT1 |
| GO_AXON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 523 | 56 | ABL1,ADARB1,APBB2,APOE,B4GALT6,CDKL5,CELSR3,CHN1,CNR1,CXCL12,DAG1,DBNL,DOK1,EFNA5,EMB,EPHA1,EPHA5,ERBB2,FLRT3,FOLR1,GATA3,GFRA1,GRB7,LAMB2,LYPLA2,MAPK3,MEGF8,NFIB,NLGN3,NOG,NTN4,PAK3,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRA,PTPRO,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLITRK6,SPG11,SPTBN2,TRIM46,TRIO,TSKU,ULK2,VAX2,VSTM2L,WNT5A |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1301 | 99 | AASS,ABCD1,ACADL,ADA,ADAMTS7,ADO,ALDH1L1,ANAPC11,ANAPC16,ANPEP,AP2A1,APOBEC3C,APOBEC3G,APOE,AREL1,ASAH1,ASB9,AUH,BACE1,BGN,CAPN3,CAV3,CHMP6,CTSH,CTSO,CTSS,CTSZ,CUL9,DBT,DDO,DET1,DPYD,DPYS,EDEM3,ENTPD4,FBXL15,FBXL17,FBXL19,FBXL22,FBXO9,GPT,GPX1,HECW2,HERC2,HFE,HGSNAT,HOGA1,HPD,HPSE,HSPG2,HYAL1,IVD,KLHL22,KLHL3,KMO,KYAT1,LNPEP,LRRK2,LYPLA2,MAOA,MCCC1,MMP12,NEDD8,NEIL1,NOTUM,NUDT12,NUDT13,NUDT3,OMA1,PANO1,PDE1A,PDE7B,PDE8B,PIN1,PLEKHG5,PRKCD,PRODH,RNF150,RNF180,RNF213,SARDH,SGSH,SHMT1,SMAD3,SOCS5,STYX,TMEM129,TNFSF12,TXN2,UBA7,UBE3B,UBXN2B,USP22,VPS28,VPS37D,WDR81,WNT5A,ZRANB1,ZYG11B |
| GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 261 | 38 | ADGRF5,AGPAT1,AGPAT4,AJUBA,ARF3,CPNE7,DGKA,DOLK,DPM3,GPAM,GPD1,HTR2C,INPP5D,INPP5J,INPPL1,ISYNA1,LPGAT1,LPIN3,MPPE1,MTMR4,PCYT2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PITPNM2,PITPNM3,PLD1,PLEKHA1,PLSCR1,PNPLA3,PPARD,RUFY1 |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1016 | 84 | ADA,ADAM21,ADAMTS2,ADGRG2,AGT,ANGPT2,APOL2,AR,ARID4A,ATP1A4,AXL,B4GALT1,BAD,BMP4,C9orf24,CADM1,CCDC87,CNR1,CYP27B1,DDO,DEFB1,DKKL1,DNMT3A,FBLN1,GIP,GLIPR1L1,H3-3A,HERC2,HFE,HPGD,HSPA1L,IGFBP5,IGSF8,KLHL10,LDOC1,LEPR,LIMK2,LNPEP,LRRK2,MAPK3,MMP2,MMP7,NPHP1,NR2F2,PDE3A,PLB1,PLCB1,PLCD4,PLEKHA1,PPARD,PSG1,PSG3,PYGO2,RLN1,RNASE10,ROS1,RXRA,SELENOP,SERPINA5,SIX5,SLC2A14,SLC2A8,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,SPIN1,SPIN2B,STAT3,STS,TDRD9,THRA,TMEM203,TOB2,TP63,TSNAXIP1,TSPAN8,TUT4,VCX,VDR,WASHC5,ZBTB16,ZNF541 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1652 | 1208 | 94 | ABL1,ADCY6,AGT,APPL2,AR,ATP6V0A4,AXL,BACE1,BAD,BCAR1,BRINP3,CCND3,CD36,COL1A1,COL1A2,COL3A1,COL5A2,CYP27B1,DAG1,DNMT3A,EFNA5,EIF4EBP2,EPHA5,FAM210B,FFAR3,FOLR1,GDAP1,GNA14,GNAI1,GNAQ,GPD1,GPER1,HMGN3,HTR2C,IGF1R,IGFBP5,JAGN1,KANK2,KAT2B,KLF15,KLHL22,KMO,LAMTOR1,LDOC1,LPIN3,LRRK2,LYPD1,MAPK3,MMP2,MSTN,MYD88,NCOA5,NSMF,OR51E2,OSR1,P2RY11,PDCD4,PDE3A,PDGFC,PDGFD,PIK3R1,PIK3R2,PIK3R3,PKD2,PLCB1,PLEKHA1,PLSCR4,PPARD,PRKCD,PRKD1,PTGER2,PTPN22,PTPRA,RAF1,RAPGEF2,RARG,RARRES2,RDH11,RECQL5,RORC,SERPINF1,SESN1,SHMT1,SIDT2,SLC2A8,SPAAR,STAR,STAT3,TP53,TPM1,TRPM2,VDR,WNT5A,ZBTB7B |
| GO_STEROID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 331 | 43 | ACADL,ACLY,AGT,APOE,APOL1,APOL2,ASAH1,BMP5,CEL,CETP,CYP17A1,CYP27B1,CYP2E1,CYP7B1,DKK3,DKKL1,EBPL,GPAM,HSD17B1,HSD3B7,LAMTOR1,LEPR,LIMA1,OSBPL5,OSBPL9,PLEKHA1,PPARD,REST,RORC,RXRA,SCARF1,SCP2,SERPINA6,SLC27A2,STAR,STS,SULT1A1,SULT1B1,SULT1E1,TRERF1,TTC39B,UGT2B11,VDR |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 928 | 79 | ABL1,ADCY6,ADGRG1,ADGRL3,AGT,AP2A1,APOE,APPL2,ASCL1,BHLHB9,BMP4,BMP5,BRINP3,CDKL5,CELSR1,CFL1,CHN1,CNR1,COL3A1,CSMD3,CTSZ,CUX2,CXCL12,DAG1,DBNL,DGUOK,DKK1,DLG5,DLL1,EFNA5,EIF2AK4,EYA1,FAIM,FLRT3,GATA3,GDF5,GPER1,GPR183,HECW2,IL1RAPL2,INPP5J,IRX3,ITSN1,LRRC24,LRRK2,MEGF8,MEIS1,MME,NCKIPSD,NLGN3,NOG,NSMF,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRO,RAC3,RAPGEF2,RARG,REST,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SLITRK6,STAR,STAT3,TP53,TRIM46,ULK2,WASHC5,WNT5A |
| GO_MUSCLE_CONTRACTION | 0.0e+00 | 0.0e+00 | 1652 | 362 | 45 | ACE2,ACTA2,ACTG2,ADA,AGT,ANK2,ANKRD2,ATP1A2,CALM3,CASQ1,CAV3,CCDC78,CTNNA3,DMPK,EDNRA,F2R,GPER1,GSTM2,KCNE3,KCNE4,KCNJ3,KLHL41,LMOD1,MB,MYL9,MYLK,MYOF,MYOM1,MYOM3,PLCE1,PPP1R13L,RCSD1,SCN1A,SCN2B,SNTB1,STAC2,TLN1,TMOD1,TNNC1,TNNI2,TPCN2,TPM1,TPM4,UTRN,VEGFB |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 348 | 44 | ABL1,APPL2,ATOH8,BMP4,BMP5,CAV3,CDKN1C,CDKN2B,COL1A2,COL3A1,DAND5,DKK1,DKK3,EID2,ENG,FBXL15,FKBP8,FOLR1,FOXH1,FSTL1,GDF5,HFE,HPGD,INHA,LNPEP,MAPK3,MEGF8,MSTN,MTMR4,NOG,PBLD,PCSK6,PDCD4,PIN1,PMEPA1,RASL11B,RBPMS,SMAD3,SNX25,TAB1,TGFBR3,TP53,WNT5A,ZBTB7A |
| GO_BEHAVIOR | 0.0e+00 | 0.0e+00 | 1652 | 598 | 60 | ABCA7,ACE2,ADA,ADARB1,ADGRL3,AFF2,AGT,APLN,APOE,ATP1A2,BHLHB9,BTG2,CELSR1,CNR1,CNTNAP2,CNTNAP4,CUX2,CXCL12,DACH1,DDO,DKK1,DPP4,EIF2AK4,EIF4EBP2,EN1,GIP,GMFB,GRM1,HTR2C,KLHL1,LEPR,LHX8,LRRK2,LYPD1,MEIS1,MME,NAV2,NLGN3,NPHP1,PAK6,PEX13,PLCB1,PTGDS,RNF180,SCN1A,SELENOP,SERPINF1,SLITRK6,SPG11,SPTBN2,STAR,STAT3,STRA6,SYNPO,TAL1,THRA,TMOD1,TP53,VPS13A,ZIC1 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 823 | 73 | ABL1,ADARB1,AGT,AJUBA,ANXA8,ANXA8L1,AOC3,APOC3,APOE,BEX3,BMP4,C3,C4A,C4B,CAAP1,CABIN1,CAV3,CDKN1C,CDKN2B,CHMP6,CNR1,CR1,CRIM1,CYP27B1,DUSP19,EPHA1,GCHFR,GMFB,GNAQ,GPX1,HEXIM1,HEXIM2,IGF1R,IKBKB,ITIH3,KAT2B,LAX1,LEPR,LRRK2,MAP2K5,MLLT1,MSTN,NEIL1,NPR3,NR2F2,PAPLN,PARP3,PARP9,PCIF1,PDCD4,PDE6G,PLXNB3,PPP1R35,PRKCD,PTPA,PTPN22,PTPRC,RAF1,RTKN,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SOCS5,SPINK9,SSPO,STYX,TP53,VIL1,WDR81,WFDC1,WFDC8 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1652 | 469 | 52 | ABL1,ADARB1,AJUBA,ANGPT1,APOE,BMP4,CALM3,CAV3,CDKN1C,CDKN2B,CHMP6,DAG1,DKK1,DNAJC15,DUSP19,ENG,EPHA1,F2RL1,FBLN1,FKBP8,GMFB,GNAQ,GPER1,HEXIM1,HEXIM2,IGF1R,INHA,INPP5J,KAT2B,LAX1,LRRK2,MECOM,MLLT1,MSTN,NNT,NOG,NR2F2,PBLD,PDCD4,PFKFB1,PIK3R2,PIN1,PIP5KL1,PMEPA1,PRKCD,PSCA,PTPN22,PTPRC,SNX25,SOCS5,STAT3,ZBED3 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1652 | 1198 | 93 | ABL1,APLN,AR,ARID4A,ASCL1,ATAD2B,ATOH8,BMP4,BMP5,CARF,CDKN2B,CREB3L1,DLL1,DPF3,EBF1,EHF,EN1,ENG,EYA1,F2RL1,FHOD1,FOXD3,FOXH1,GATA3,GLIS1,GPER1,HMGN3,HOXA4,HOXA7,HOXC13,IKBKB,KAT2B,KLF15,LHX8,LPIN3,MAFB,MAP2K5,MAPK3,MAVS,MC1R,MEIS1,METTL23,MITF,MLIP,MMP12,NFIA,NFIB,NFIC,NFIX,NOG,OSR1,PIK3R1,PIK3R2,PIN1,PKD2,PLAC8,PLSCR1,POU3F3,PPARD,PRKD1,RAF1,RARG,RFXANK,RXRA,SENP2,SERPINF2,SIX5,SMAD3,SMARCA2,SOX12,SOX5,SSBP2,STAT3,STK16,TAL1,TBX18,TCEA2,TFEB,THRA,TP53,TP63,USF2,VDR,WNT5A,YY2,ZBED3,ZBTB16,ZBTB7B,ZIC1,ZNF219,ZNF497,ZNF76,ZNF821 |
| GO_NEGATIVE_REGULATION_OF_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 1652 | 350 | 44 | ADA,ADARB1,ADGRG1,ALOX15B,ANGPT2,ANGPT4,APOE,ARPIN,BMP5,CCL28,COL3A1,CXCL12,CYGB,DACH1,DAG1,DLG5,ENG,EPHA1,FBLN1,GATA3,GCSAM,HOXA7,IGFBP5,IL27RA,MAP2K5,MCC,MITF,MMP28,NOG,NR2F2,PADI2,PBLD,PIN1,PIP5KL1,PLCB1,PLXNB3,PPARD,PTPRU,RIPOR2,SERPINF1,STARD13,STAT3,TIE1,TPM1 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1652 | 1258 | 96 | ABL1,AGBL2,AGBL4,AGBL5,AGT,ANGPT1,ANGPT4,ARID4A,ART3,AXL,AZU1,B4GALNT2,BCOR,BGN,BLOC1S1,CALCR,CALM3,CAPN3,CD36,CD4,CDC42BPB,CHMP6,DKK1,DMPK,DOCK3,DPF3,DPM3,DPY19L4,EFEMP1,EFNA5,EID1,EPHA1,EPHA5,ERBB2,EYA1,FGF7,FGR,FKBP5,FKBP8,FOLH1,GATA3,IGF1R,IKBKB,IKBKE,IL27RA,IL6R,INPP5J,KANSL1L,KAT14,KAT2B,KLF15,LIPT2,LOXL3,LRRK2,MAP2K5,MAP3K12,MAPK3,MECOM,MTCP1,NAA80,P3H2,P4HTM,PADI2,PARP9,PDGFC,PDGFD,PIAS3,PIN1,PKDCC,PPIL2,PRKCD,PRKD1,PRKY,PRMT6,PTPA,PTPRC,PYGO2,RAF1,ROS1,SENP2,SOCS5,STAT3,STK16,STK32C,STOX1,TAL1,TIE1,TNKS1BP1,TP53,TTLL10,USP22,VPS33B,WNK3,WNT5A,ZDHHC12,ZDHHC21 |
| GO_EXOCYTOSIS | 0.0e+00 | 0.0e+00 | 1652 | 900 | 77 | ABCA12,ACLY,ACTN1,ACTN4,ACTR1B,AGL,ALDH3B1,ANPEP,ARPC5,ARSA,ASAH1,ATP8B4,AZU1,B4GALT1,BACE1,C3,CADPS2,CALM3,CD33,CD36,CLEC3B,CNN2,CNR1,CPPED1,CR1,CRISP3,CRISPLD2,CTSH,CTSS,CTSZ,DBNL,F2RL1,FCGR2A,FGR,FPR1,HGSNAT,HPSE,ISLR,ITIH3,ITSN1,JAGN1,LAMTOR1,LRRK2,METTL7A,MME,MMP25,NFAM1,OLR1,ORM1,PADI2,PLAC8,PLD1,PRKCD,PTPRB,PTPRC,RARRES2,REST,SELENOP,SERPINA3,SERPINF2,SLC27A2,SPARC,SV2A,SYN2,SYT12,SYTL1,TAGLN2,TEX264,TLN1,TMEM63A,TRPM2,UNC13C,VAMP8,VEGFB,VPS33B,VPS41,VWF |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1652 | 1030 | 84 | ABL1,ACKR3,ADA,ANGPT1,ANGPT4,APBB2,APOE,AR,AREL1,ASCL1,AXL,AZU1,BAD,BEX3,BHLHB9,BMP4,BMP5,BOK,BTG2,CAAP1,CAPN3,CCN5,CCR7,CFL1,CLDN7,CREB3L1,CTSH,CXCL12,DKK1,DLL1,EN1,ERCC5,EYA1,F2R,FAIM,FKBP8,GATA3,GDF5,GPAM,GPX1,HSH2D,IGF1R,IKBKB,ITSN1,KANK2,LIMS2,LRRK2,MAP2K5,MAP3K12,MECOM,MITF,MYD88,MYO18A,NNT,NOG,NRBP2,OSR1,PDCD4,PDE3A,PDPN,PIK3R1,PIN1,PKHD1,PLAC8,POU3F3,POU3F4,PPARD,PRKCD,PRKD1,PSEN2,RAF1,REST,SERPINF1,SMAD3,STAR,STAT3,TIAF1,TMBIM4,TP53,TWIST2,VIL1,VSTM2L,WNK3,WNT5A |
| GO_IMPORT_INTO_CELL | 0.0e+00 | 0.0e+00 | 1652 | 810 | 72 | ABCA7,ABL1,ACKR3,ACTN4,AGT,ANGPT1,ANK2,AP2A1,APLN,APOC3,APOE,APOL1,APPL2,ARL6IP5,ATP1A2,ATP1A4,AXL,C3,CACNG8,CALCR,CALM3,CAV3,CD36,CEL,DBNL,DKK1,DLL1,DNM1,DOCK1,EEA1,EHD2,F2RL1,FOLR1,GPM6B,HFE,HOOK2,HSPG2,IGHV3-73,INPPL1,ITSN1,JCHAIN,KCNJ16,KCNJ3,LOXL3,LRP1B,LRRK2,MAPK3,MRC2,MYO1E,NLGN3,PIK3CB,PRKD1,RAMP1,RIN2,RUFY1,SBSPON,SCARF1,SCARF2,SLC12A9,SLC1A1,SLC27A2,SLC27A4,SLC9A9,SPARC,SSC4D,SSC5D,TBC1D5,TMPRSS5,TRPM2,VPS28,WNK3,WNT5A |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 620 | 61 | AGL,AMY1B,AMY2B,AOAH,AP2A1,B3GLCT,B3GNT10,B4GALT1,B4GALT6,BAD,CASD1,CHI3L2,CHST14,CHST9,DPM3,ENO3,ENO4,ENTPD5,EXT2,FCSK,GLB1L,GPD1,GPER1,GYG2,HYAL1,IDNK,IMPA2,INPP5A,INPP5J,INPPL1,ISYNA1,JMJD8,KAT2B,LEPR,MAN2B2,MYOF,NDST1,NDST4,OMA1,PFKFB1,PGGHG,PIGQ,POMT1,PPARD,PPP1CB,PYGM,RORC,SIAE,SLC25A1,SLC2A8,SLC5A2,SLC5A3,ST3GAL6,ST6GALNAC5,ST6GALNAC6,STAT3,TKTL1,TP53,UGT1A6,UGT2B11,ZBTB7A |
| GO_MUSCLE_STRUCTURE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 673 | 64 | ABL1,ADAM12,ADARB1,AGT,ALPK3,ANK2,ANKRD2,BMP4,BTG2,CAPN3,CASQ1,CAV3,COL3A1,DKK1,DLL1,DMPK,EHD2,EID2,ENG,FHOD3,FLOT2,FOXH1,GPER1,GPX1,H3-3A,IGFBP5,IGSF8,ITGA11,JPH2,KLHL41,LDB3,LMOD1,MEIS1,MRAS,MSTN,MYLK,MYOF,MYOM1,MYOM3,NEBL,NOG,NR2F2,OBSL1,PDCD4,PDLIM1,PIN1,PLCB1,PLPP7,PPARD,PRICKLE4,PRR14,RANBP3L,REST,RIPOR2,RXRA,SELENON,SMAD3,STRA6,TGFBR3,TMOD1,TNNC1,TPM1,UTRN,WNT5A |
| GO_METAL_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 906 | 77 | ABL1,ACTN4,AGT,ANK2,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CD33,CD4,CXCL12,CYP27B1,DMPK,EFHB,F2R,FXYD3,GPER1,GRAMD2A,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,KLHL3,MYLK,NALCN,NIPAL2,OSR1,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,RAMP1,SCN1A,SCN2B,SCNN1B,SELENON,SLC12A9,SLC13A4,SLC20A2,SLC22A5,SLC24A5,SLC38A10,SLC5A2,SLC5A3,SLC9A9,STAC2,STEAP3,STIM1,STIMATE,TCN2,TMC1,TPCN2,TRPC4,TRPM2,UTRN,VDR,WNK3 |
| GO_EMBRYONIC_ORGAN_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 434 | 49 | ADA,BMP4,BMP5,CCDC40,CDKN1C,CELSR1,DLL1,EFEMP1,EN1,ENG,EYA1,FOLR1,FOXH1,FZD6,GATA3,HOXA4,HOXA7,HYAL1,IFT140,MAFB,MAPK3,MEGF8,NDST1,NOG,NR2F2,OSR1,PDGFC,PKD2,PKDCC,POU3F4,PPP1R13L,RARG,RARRES2,RIPOR2,SENP2,SLITRK6,SMAD3,STOX1,STRA6,TAL1,TFEB,TP53,TRIOBP,TSHZ1,TTC39C,VAX2,WDR60,WNT5A,ZIC1 |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 1124 | 88 | ABCD1,ACE2,ADA,AGT,ANGPT2,APOBEC3G,APOE,APPL2,AZU1,BACE1,C3,CACNB3,CADM1,CAPN3,CCR7,CD36,CNR1,CR1,CTSS,CUEDC2,CXCL12,CYP27B1,EIF2AK4,ERBIN,F2R,F2RL1,FFAR3,FGR,GATA3,GPER1,GPR183,GPX1,HEXIM1,HPSE,IKBKB,IKBKE,IL17RC,IL1R1,IL6R,KANK2,LRRK2,MAPK3,MAVS,MEGF8,MGST2,MMP12,MMP28,MSTN,MUC15,MYD88,NLRX1,PADI2,PAK3,PARP9,PDCD4,PDE6A,PDE6G,PDGFD,PDPN,PLSCR1,PPARD,PPM1B,PRKCD,PRKD1,PTPN22,PTPRC,PTPRO,RAF1,RARRES2,RIPOR2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SMAD3,SOCS5,SPAAR,TAB1,TLR1,TSPAN8,VAMP8,VEGFB,WFDC1,WNT5A |
| GO_DRUG_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 600 | 59 | AASS,ABCD1,ACLY,ADA,ADI1,AGT,AK1,AK3,ALDH1L1,ALDH3B1,BDH2,BGN,BMP5,CBR4,CD36,CHST14,CKB,CTSH,CYP17A1,CYP27B1,CYP2C18,CYP2E1,CYP4B1,DKK3,DMAC2L,DPYD,DPYS,ELOVL3,ELOVL5,FMO1,FMO2,FOLR1,GCHFR,GPX1,HPD,KMO,KYAT1,LIPT2,MAOA,MCCC1,NNT,NPR1,PKD2,PNKD,REST,SCP2,SHMT1,SLC52A1,SMAD3,SNCAIP,STAR,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,TCN2,TKTL1,TPK1 |
| GO_EPITHELIAL_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 774 | 69 | ABCA12,ABL1,ACTA2,ADAMTSL4,ALOX15B,AR,ARID4A,ASAH1,ASCL1,ATOH8,B4GALT1,BAD,BDH2,BMP4,BMP5,CCDC78,CDKN1C,COL18A1,CYP27B1,DLG5,DLL1,EHF,ENG,F2RL1,FRMD6,GATA3,GPX1,GSTA1,GSTA2,HOXA7,IKBKB,KLF15,KRT14,KRT5,KRT7,KRT81,KRTAP1-5,LAMB2,MYO1E,NFIB,NR2F2,OSR1,PCSK6,PDPN,PLAAT4,PPL,PTPRO,RAPGEF2,RARG,RIPOR2,ROS1,RXRA,SHROOM3,SIDT2,SLITRK6,SMAD3,SPINK9,SULT1B1,TAGLN2,TCHH,TGM1,THRA,TMC1,TMOD1,TP63,TRIOBP,VDR,VIL1,WNT5A |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 587 | 58 | ABL1,ADARB1,AJUBA,ANGPT1,APOE,BMP4,CABIN1,CALM3,CAV3,CDKN1C,CDKN2B,CHMP6,DAG1,DKK1,DNAJC15,DUSP19,ENG,EPHA1,F2RL1,FBLN1,FKBP8,GMFB,GNAQ,GPER1,HEXIM1,HEXIM2,IGF1R,IKBKB,INHA,INPP5J,KAT2B,LAX1,LRRK2,MECOM,MLLT1,MSTN,NNT,NOG,NR2F2,PBLD,PCIF1,PDCD4,PFKFB1,PIK3R2,PIN1,PIP5KL1,PMEPA1,PPP1R35,PRKCD,PSCA,PTPA,PTPN22,PTPRC,SNX25,SOCS5,STAT3,WDR81,ZBED3 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1652 | 1037 | 83 | ABCA12,ABCA7,ABL1,ALOX15B,ANGPT1,ANXA13,APOE,AR,BAD,BMP4,CACNB3,CADM1,CAV3,CCR7,CD33,CD36,CELSR3,CNR1,CRP,DAG1,DPP4,EFNA5,EPHA5,ERBB2,F2R,F2RL1,FGR,GATA3,GIP,GNAI1,GPAM,GPER1,GPM6B,HADH,HFE,HMGN3,HSPA1L,IL17RC,IL27RA,IQSEC2,JAGN1,KCNN4,LRRK2,LYPD1,MAPK3,MAVS,MMP12,MYO18A,MYOM1,OR51E2,ORM1,PARP9,PDZK1,PIK3R1,PIK3R2,PIN1,PKDCC,PPARD,PRKCD,PTPN22,RAB11FIP3,REST,RIPOR2,SEC16A,SIDT2,SMAD3,SSC5D,STAC2,STX10,TAX1BP3,TLR1,TP53,TP63,TRIM22,TRIM29,TRIM46,UBXN2B,VAMP8,VIL1,VPS28,WNK3,WNT5A,ZIC1 |
| GO_RESPIRATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 201 | 32 | ABCA12,ADA,ADAMTS2,ASCL1,BMP4,CCBE1,CCDC40,CELSR1,CRISPLD2,CTSH,CTSZ,DAG1,DLG5,ESRP2,FGF7,IGFBP5,LOXL3,MAPK3,MME,NFIB,NOG,PDPN,PKDCC,RARG,RSPO2,SELENON,SPARC,STRA6,TAB1,THRA,TNS3,WNT5A |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1652 | 709 | 65 | ABL1,ADCY6,AGT,APPL2,ATP6V0A4,BACE1,BCAR1,CAV3,CCND3,CD36,COL1A1,COL1A2,COL3A1,COL5A2,DNMT3A,EIF4EBP2,FFAR3,FOLR1,GNA14,GNAQ,GPD1,GPER1,GSTM2,HTR2C,IGF1R,IGFBP5,KAT2B,KLF15,KLHL22,LAMTOR1,LDOC1,LPIN3,LRRK2,LYPD1,MAPK3,MAVS,MMP2,MSTN,NCOA5,NSMF,P2RY11,PDE3A,PDGFC,PDGFD,PIK3R1,PIK3R2,PIK3R3,PKD2,PLCB1,PRKCD,PTPN22,PTPRA,RAPGEF2,RARRES2,RECQL5,SELENON,SESN1,SHMT1,SLC2A8,SPAAR,STAR,STAT3,TP53,TRPM2,ZBTB7B |
| GO_REGULATION_OF_CELL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 491 | 52 | ABL1,ACTN4,APOE,ARPIN,BHLHB9,CDKL5,CFL1,CHN1,CUX2,CXCL12,DAG1,DBNL,DOCK1,EFNA5,FBLN1,FGD3,FGD4,FGR,HECW2,LIMS2,LRRK2,MEGF8,NLGN3,NSMF,OBSL1,PAK3,PALM2AKAP2,PALMD,PARVB,PDPN,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRO,RAC3,RAPGEF2,RHOBTB2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SHROOM3,SPARC,TPM1,TRIM46,TRIOBP,ULK2,VIL1,WNT5A,ZMYM3,ZRANB1 |
| GO_REGULATION_OF_HORMONE_LEVELS | 0.0e+00 | 0.0e+00 | 1652 | 524 | 54 | ACE2,AGT,ALDH9A1,APLN,BAD,BMP5,CHST9,CNR1,CPA3,CPE,CTSZ,CYP17A1,CYP27B1,CYP2C18,DDO,DKK3,DKKL1,DPP4,EFNA5,EPHA5,FFAR3,GATA3,GIP,GPER1,HADH,HFE,HMGN3,HSD17B1,HTR2C,INHA,ITSN1,JAGN1,MME,NMB,PCSK6,PCSK7,PLB1,PLEKHA1,PPARD,RAB11FIP3,RAF1,RDH11,RDH14,REST,SERPINA6,SIDT2,STAR,SULT1A1,SULT1B1,SULT1E1,TRERF1,UGT2B11,VAMP8,VDR |
| GO_NEURON_PROJECTION_GUIDANCE | 0.0e+00 | 0.0e+00 | 1652 | 282 | 38 | APBB2,CELSR3,CHN1,CXCL12,DAG1,DOK1,EFNA5,EMB,EPHA1,EPHA5,ERBB2,FLRT3,GATA3,GFRA1,GRB7,LAMB2,LYPLA2,MAPK3,MEGF8,NFIB,NOG,NTN4,PIK3CB,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRA,PTPRO,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPTBN2,TRIO,VSTM2L,WNT5A |
| GO_RESPONSE_TO_LIPID | 0.0e+00 | 0.0e+00 | 1652 | 930 | 77 | ABL1,ADCY6,AGL,AGT,ALDH3A1,AR,ASCL1,ATP1A2,AXL,BAD,BMP4,BRINP3,CALCR,CALM3,CCR7,CD36,CD4,CNR1,COL1A1,CTSH,CYP27B1,CYP7B1,DAG1,DKK1,DNMT3A,EFNA5,ENG,ERBIN,F2R,FAM210B,FFAR3,FMO1,FOXH1,GDAP1,GIP,GNAI1,GPAM,GPER1,HPGD,KANK2,KMO,LDOC1,MAPK3,MGST2,MSTN,MYD88,NR2F2,NR2F6,OR51E2,OSR1,PADI2,PDCD4,PFKFB1,PLSCR4,PMEPA1,PPARD,PTGER2,PTPN22,PTPRU,RARG,REST,RORC,RXRA,SERPINF1,SPARC,STAR,STAT3,TGFBR3,THRA,TIE1,TP53,TP63,VDR,WFDC1,WNT5A,ZBTB7A,ZNF366 |
| GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1652 | 544 | 55 | ABL1,AGT,AJUBA,AP2A1,AR,BMP4,BMP5,CAV3,CCDC40,CELSR1,CELSR3,CFL1,CTSH,CTSZ,CYP7B1,DAG1,DKK1,DLG5,DLL1,EDNRA,ENG,ESRP2,EYA1,FGF7,FLRT3,FMN1,FOLR1,FOXH1,FZD6,GATA3,IGFBP5,IRX3,KLHL3,LAMA3,MEGF8,MMP12,NOG,NTN4,OSR1,PDPN,PKD2,PLXNB2,RARG,RSPO2,RXRA,SEMA3C,SEMA3E,SHROOM3,SMAD3,STARD13,STOX1,TBX18,TP63,VDR,WNT5A |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 463 | 50 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADA,ADCY6,AK1,AK3,BAD,CBR4,DBI,DGUOK,DMAC2L,DPYD,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD5,GPAM,GPD1,GPX1,HACD1,HACD2,JMJD8,LRRK2,NME3,NME4,NPR1,NUDT3,PANK1,PDE1A,PDE7B,PDE8B,PDP2,PFKFB1,SHMT1,SLC25A1,SLC26A1,SLC26A2,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,ZBTB7A |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 990 | 80 | ABL1,ACTN1,ADA,ADGRF5,ANGPT1,ARID4A,AXL,BAD,BMP4,CCR7,CD4,CDKN1C,CDKN2B,CIAO3,CR1,CRIP2,CTLA4,CXCR5,DLL1,DOCK11,ERBB2,F2RL1,FAM210B,GATA3,GPR183,H3-3A,H3C6,HOXA7,IL27RA,INHA,INPP5D,JAGN1,KAT2B,LEPR,LOXL3,LY6D,MAFB,MAPK3,MB,MECOM,MEIS1,MITF,MYL9,MYO1E,NFAM1,NFE2,P4HTM,PARP3,PDPN,PHLPP1,PIAS3,PIK3R1,PLD4,PMS2,PRMT6,PRR7,PRXL2A,PTPN22,PTPRC,RAF1,RARG,REST,RHAG,RORC,SEMA4A,SMAD3,SOCS5,STAT3,TAL1,TGFBR3,THRA,TOB2,TP53,TRPM2,TTC7A,WNT5A,ZBTB16,ZBTB7A,ZBTB7B,ZNF784 |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 879 | 74 | ABL1,ACTN4,AGT,ANK2,ATP13A1,ATP1A2,ATP1A4,ATP6V0A4,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CNGB3,CTSS,DMAC2L,F2R,FXYD3,GPER1,GSTM2,HECW2,HFE,HTR2C,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,NALCN,NIPAL2,NLGN3,NNT,OSR1,PDZK1,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,RHAG,SCN1A,SCN2B,SCNN1B,SELENON,SLC12A9,SLC15A2,SLC1A1,SLC20A2,SLC22A5,SLC24A5,SLC2A8,SLC41A3,SLC9A9,STAC2,STEAP3,STIM1,STIMATE,TMC1,TMEM63A,TPCN2,TRPC4,TRPM2,UCP2,UTRN,WNK3 |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 423 | 47 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ADCY6,AK1,AK3,BAD,CBR4,CTPS2,DBI,DMAC2L,ELOVL3,ELOVL5,ENO3,ENO4,ENTPD4,ENTPD5,GPAM,GPD1,HACD1,HACD2,JMJD8,LRRK2,NME3,NME4,NPR1,NUDT3,PANK1,PDE1A,PDE7B,PDE8B,PDP2,PFKFB1,SLC25A1,SLC26A1,SLC26A2,STAT3,SUCLG2,SULT1A1,SULT1B1,SULT1E1,ZBTB7A |
| GO_INFLAMMATORY_RESPONSE | 0.0e+00 | 0.0e+00 | 1652 | 765 | 67 | ABCD1,ACE2,ACKR1,ADA,AGT,AOC3,APOE,APOL2,APOL3,APPL2,ATRN,AXL,AZU1,B4GALT1,C3,C4A,C4B,CCR7,CD36,CERS6,CNR1,CRP,CUEDC2,F2R,F2RL1,FFAR3,FPR1,GATA3,GPER1,GPX1,HFE,HSPG2,HYAL1,IKBKB,IL17RC,IL17RE,IL1R1,IL6R,LOXL3,LRRK2,MGST2,MMP25,MYD88,NDST1,NFAM1,NLRX1,OLR1,ORM1,PARP4,PDCD4,PLSCR1,PPARD,PRKCD,PRKD1,PTGER2,PTPRC,RARRES2,SERPINA3,SERPINF1,SERPINF2,SMAD3,SOCS5,STAT3,TLR1,VAMP8,WFDC1,WNT5A |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1652 | 802 | 69 | ABCA12,ABCA7,ABL1,ANGPT1,ANK2,ANXA13,AR,ATP1A2,BAD,BMP4,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CD36,CD4,DAG1,EFNA5,EHD2,EPHA5,ERBB2,F2R,FGR,GAS1,GNAI1,GPER1,GPM6B,GSTM2,HFE,HMGN3,HSPA1L,IQSEC2,JAGN1,JPH2,LRRK2,LYPD1,MAPK3,MAVS,NLGN3,PARP9,PDZK1,PIK3R1,PIK3R2,PIN1,PKD2,PKDCC,PRKCD,RIPOR2,SCP2,SEC16A,SELENON,SIDT2,SMAD3,STAC2,TAX1BP3,TNNC1,TP53,TP63,TRIM29,TRIM46,UBXN2B,VAMP8,VIL1,VPS28,WNK3,WNT5A,ZIC1 |
| GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 251 | 35 | AGPAT1,AGPAT4,AJUBA,ARF3,C3,CPNE7,DGKA,DPM3,GPAM,GPD1,HTR2C,INPP5D,INPP5J,INPPL1,LPIN3,MPPE1,MTMR4,PCYT2,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PITPNM2,PITPNM3,PLCE1,PLD1,PLEKHA1,PLSCR1,PNPLA3,RUFY1 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1187 | 89 | ABL1,ADA,APPL2,ARPC5,AXL,BAD,BCAR1,BTN3A3,C1R,C1RL,C3,C4A,C4B,CACNB3,CADM1,CCR7,CD36,CD4,CD99L2,CFB,CNR1,CR1,CRP,CTLA4,CTSS,CXCL12,DOCK1,DPP4,EIF2AK4,ERBIN,F2RL1,FAM210B,FCGR2A,FFAR3,FGR,FLOT2,FPR1,GATA3,GCSAM,GPAM,GPR183,HEXIM1,HFE,IGHV3-73,IKBKB,IKBKE,IL1R1,IL27RA,IL6R,INPP5D,KCNN4,LAX1,LRRK2,MAPK3,MAVS,MMP12,MSTN,MUC15,MYD88,MYO18A,NCKIPSD,NFAM1,NLRX1,PAK3,PARP9,PDGFD,PIK3CB,PIK3R1,PIK3R2,PLEKHA1,PLSCR1,PRKCD,PTPN22,PTPRC,PVRIG,RAF1,RARRES2,RIPOR2,SOCS5,STAT3,TAB1,TAL1,TLR1,TP53,VAMP8,VEGFB,WNT5A,ZBTB16,ZBTB7B |
| GO_CYTOKINE_PRODUCTION | 0.0e+00 | 0.0e+00 | 1652 | 808 | 69 | ABCD1,ABL1,ACE2,ACKR1,ADGRG1,AGPAT1,AGT,ALOX15B,ANGPT1,ANKRD2,APPL2,AXL,AZU1,C3,CADM1,CCBE1,CCR7,CD33,CD36,CD4,CRP,CUEDC2,DLL1,ERBIN,F2R,F2RL1,FFAR3,FGR,GATA3,GPAM,HFE,HPSE,IKBKE,IL17RC,IL1R1,IL27RA,IL6R,INHA,INPP5D,ITGB8,LRRK2,MAP2K5,MAPK3,MAVS,MC1R,MMP12,MR1,MYD88,NFAM1,NLRX1,ORM1,PDCD4,PIK3R1,PIN1,PLCB1,POLR2L,PPM1B,PRKCD,PTPN22,PTPRC,SERPINF2,SMAD3,SOCS5,SSC5D,STAT3,TLR1,UBA7,WNT5A,ZBTB7B |
| GO_REGULATION_OF_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 699 | 63 | ABCA7,ABL1,ACE2,ACTN4,AGT,ANK2,APOE,ARL6IP5,ATP1A2,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CD33,CD4,CLCNKA,CLIC3,CNR1,CTSS,CXCL12,DMPK,EFHB,F2R,FXYD3,GPER1,GPM6B,GRAMD2A,GSTM2,HECW2,HFE,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KMO,MYLK,NALCN,NLGN3,OSR1,PDZK1,PKD2,PRKCD,PSEN2,ROS1,SCN1A,SCN2B,SELENON,STAC2,STIM1,STIMATE,SV2A,SYT12,TMC1,TPCN2,UTRN,VAMP8,WNK3 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 0.0e+00 | 0.0e+00 | 1652 | 649 | 60 | ABL1,ADA,ADGRF5,ANGPT1,AR,AXIN2,BCOR,BMP4,BMP5,CDKN1C,CELSR1,CFL1,COL1A1,CPT2,DKK1,DLL1,EDNRA,EN1,EYA1,FBLL1,FKBP8,FOLR1,FOXD3,FZD6,GATA3,HOPX,HOXA4,HOXA7,HYAL1,IFT140,LPAR6,MEGF8,MYO1E,NDST1,NECAB1,NOG,NR2F2,OSR1,PKD2,PLXNB2,PTPN18,PYGO2,RARG,RXRA,SEMA3C,SENP2,SHROOM3,SLC35D1,SMAD3,TAB1,TBC1D32,TBX18,TFEB,TIE1,TMEM107,TP53,USP22,WDR60,WNT5A,ZNF358 |
| GO_LIPID_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1652 | 417 | 46 | ABCA12,ABCA4,ABCA7,ABCA8,ABCC3,ABCD1,AGT,APOC3,APOE,APOL1,APOL2,APOL3,APOL4,ATP8B4,C3,CD36,CEL,CETP,CPT2,CRP,IKBKE,KCNN4,LAMTOR1,LIMA1,MTTP,NMB,NME4,OSBPL5,OSBPL9,PITPNM2,PLSCR1,PLSCR4,PPARD,PRKCD,RXRA,SCP2,SERPINA5,SLC27A2,SLC27A4,SLCO1B1,SLCO2A1,STAR,STARD6,STRA6,TNFAIP8L3,TTC39B |
| GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 481 | 50 | ADA,ADGRF5,ANGPT1,AXL,BMP4,BMP5,CCL28,CNR1,COL3A1,CR1,CTLA4,CUEDC2,CXCL12,DLG5,DLL1,ERBB2,ERBIN,F2RL1,FGR,GCSAM,GPAM,GPER1,GPX1,HFE,HOXA7,IL27RA,INHA,INPP5D,LAX1,LOXL3,MAFB,MEIS1,MMP12,MMP28,NLRX1,PADI2,PARP3,PIAS3,PIK3R1,PLCB1,PPM1B,PTPN22,PTPRC,PVRIG,RIPOR2,SOCS5,TAL1,TOB2,ZBTB16,ZBTB7B |
| GO_REGULATION_OF_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 614 | 58 | ACE2,ADA,AGT,ANK2,APLN,ATP1A2,ATP1A4,CACNB3,CACNG8,CALM3,CASQ1,CAV3,CTNNA3,CUX2,DAG1,DMPK,F2R,F2RL1,FXYD3,GPER1,GRM1,GSTM2,GTF2IRD1,GTF2IRD2,HSPB7,HTR2C,IGFBP5,INHA,KCNE3,KCNE4,KCNIP3,KCNJ3,KCNK15,LRRK2,MLIP,MSTN,MTMR4,MYL9,NLGN3,NPR1,OR51E2,PIN1,PLCE1,PTGER2,PTPRO,RAB11FIP3,SCN2B,SELENON,SLC1A1,SLC22A5,SMAD3,STIM1,THRA,TNNC1,TNNI2,TPM1,UTRN,WNK3 |
| GO_SENSORY_ORGAN_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 549 | 54 | ASCL1,BMP4,BMP5,CDKN1C,CELSR1,COL5A2,COL8A2,DLL1,EFEMP1,EYA1,FKBP8,FZD6,GATA3,HOXC13,IFT140,LAMB2,LIMK2,MAFB,MAPK3,MEIS1,MITF,MYOM1,NOG,NPHP1,OSR1,PCDH15,PDE6A,POU3F4,PPP1R13L,PYGO2,RARG,RIPOR2,ROM1,RXRA,SERPINF1,SIX5,SLITRK6,SMAD3,SPARC,STAT3,STOX1,STRA6,TBC1D32,TMC1,TMOD1,TRIOBP,TRIP11,TSHZ1,TSKU,TTC39C,VAX2,WNT5A,ZDHHC16,ZIC1 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 620 | 58 | ABL1,ADARB1,ANGPT1,APOE,BCOR,BMP4,CABIN1,CALM3,CAPN3,CAV3,CDKN1C,CDKN2B,CHMP6,DAG1,DKK1,DUSP19,ENG,EPHA1,F2RL1,FBLN1,FKBP8,GMFB,GNAQ,GPER1,HEXIM1,HEXIM2,IGF1R,IKBKB,INPP5J,KAT2B,KLF15,LAX1,LRRK2,MECOM,MLLT1,NNT,NOG,NR2F2,PBLD,PDCD4,PIAS3,PIK3R2,PIN1,PIP5KL1,PMEPA1,PPP1R35,PRKCD,PRMT6,PRR7,PSCA,PTPA,PTPN22,PTPRC,SENP2,SNX25,SOCS5,VPS28,ZBED3 |
| GO_RESPONSE_TO_ACID_CHEMICAL | 0.0e+00 | 0.0e+00 | 1652 | 345 | 41 | ADCY6,ASCL1,BAD,BRINP3,CCR7,CD36,CFL1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A2,CTSH,CYP2E1,DKK1,DNMT3A,FFAR3,FOLR1,GDAP1,GIP,KLHL22,LAMTOR1,MMP2,NSMF,OR51E2,OSR1,PDGFC,PDGFD,PKD2,PTGER2,RARG,RXRA,SERPINF1,SESN1,SHMT1,SPAAR,SPARC,TGFBR3,TIE1,TP53,WNT5A |
| GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1652 | 710 | 63 | ABL1,ACLY,ACTR1B,ADA,AGL,ALDH3B1,ANPEP,ARPC5,ARSA,ASAH1,ATP8B4,AZU1,B4GALT1,C3,CD33,CD36,CNN2,CPPED1,CR1,CRISP3,CRISPLD2,CTSH,CTSS,CTSZ,DBNL,DLL1,DOCK11,EIF2AK4,F2RL1,FCGR2A,FGR,FPR1,GATA3,GPR183,HGSNAT,HPSE,IL27RA,LAMTOR1,LOXL3,METTL7A,MME,MMP25,NFAM1,OLR1,ORM1,PADI2,PARP3,PLAC8,PLD1,PRKCD,PTPRB,PTPRC,RORC,SEMA4A,SERPINA3,SLC27A2,SOCS5,STAT3,TMEM63A,TP53,TRPM2,VAMP8,ZBTB7B |
| GO_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 659 | 60 | ABL1,ADCY6,AGT,AP2A1,APOE,ASCL1,BHLHB9,BMP4,BMP5,BRINP3,CDKL5,CFL1,CHN1,CNR1,CSMD3,CTSZ,CUX2,CXCL12,DBNL,DGUOK,DKK1,DLG5,DLL1,EFNA5,EIF2AK4,EYA1,GATA3,GDF5,HECW2,INPP5J,IRX3,ITSN1,LRRK2,MEGF8,MEIS1,NCKIPSD,NLGN3,NSMF,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRO,RAC3,RAPGEF2,REST,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,TRIM46,ULK2,WASHC5,WNT5A |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1652 | 974 | 77 | ADA,ADAMTS2,ADGRG1,ADGRG2,ALOX15B,ANGPT2,AR,ARID4A,ATP1A4,AXL,B4GALT1,BAD,BMP4,BMP5,BOK,C9orf24,CADM1,CCDC87,CDKN1C,CNR1,COL9A3,CRIP1,CYP17A1,CYP27B1,CYP7B1,DACH1,DEFB1,DNMT3A,GATA3,H3-3A,HERC2,INHA,ITGB8,KLHL10,LDOC1,LHX8,LIMK2,LRRK2,MAPK3,MME,NOG,NPHP1,NR2F2,OSR1,PDE3A,PKD2,PLEKHA1,PPARD,PYGO2,RARG,ROS1,RXRA,SENP2,SERPINA5,SERPINF1,SIX5,SLC2A14,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,STAR,STRA6,TDRD9,TFEB,TMEM203,TP63,TSNAXIP1,TSPAN8,TUT4,VCX,VDR,WASHC5,WNT5A,ZBTB16,ZNF541 |
| GO_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1652 | 769 | 66 | ABCA7,ABL1,ACKR3,AJUBA,ANGPT1,APOE,AR,ARL6IP5,BMP4,BMP5,CALCR,CAV3,CCR7,CD36,CD4,DAG1,DBNL,DKK1,DUSP19,ERBB2,F2R,F2RL1,FBLN1,FPR1,GDF5,GPER1,GPR183,GRM1,HTR2C,IGF1R,INHA,LAMTOR1,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MECOM,MSTN,NDST1,NEK10,PAK3,PDCD4,PDE6G,PDGFC,PDGFD,PHLPP1,PIK3CB,PIK3R2,PIN1,PKHD1,PLCB1,PLCE1,PRKCD,PSCA,PTPN22,PTPRC,RAF1,RAPGEF2,ROS1,SERPINF2,STYX,TAB1,TNFAIP8L3,WNT5A |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 0.0e+00 | 1652 | 1210 | 89 | ACKR1,ACKR3,ACTN4,ADAMTS7,AGPAT1,ANGPT1,APPL2,ASAH1,AXL,BAD,CCR7,CD36,CD4,CFL1,CISH,CNN2,COL1A1,COL1A2,COL3A1,CXCL12,CXCR5,CYP27B1,DOK1,ERBIN,F2RL1,FOXH1,FPR1,FSCN1,GATA3,GPD1,GPER1,GSTA2,H3C6,HYAL1,IFITM2,IFITM3,IKBKB,IKBKE,IL17RC,IL17RE,IL1R1,IL1RAPL2,IL27RA,IL6R,INPP5D,INPPL1,JAGN1,KMO,LEPR,MAOA,MAP2K5,MAPK3,MAVS,MME,MMP12,MMP2,MRAS,MYD88,PADI2,PARP9,PCOLCE,PCOLCE2,PDCD4,PIAS3,PIK3CB,PIK3R1,PLCB1,PLSCR1,PRKCD,PTPN18,PTPRC,RARG,RIPOR2,RORC,SHMT1,SMAD3,SOCS5,SPARC,SPPL2B,ST3GAL6,STAR,STAT3,TAB1,TLE5,TNFRSF25,TNFSF12,TP53,TRIM22,WNT5A |
| GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | 0.0e+00 | 0.0e+00 | 1652 | 248 | 34 | APPL2,CAV3,CDKN1C,CDKN2B,CLEC3B,COL1A1,COL1A2,COL3A1,DAND5,DKK3,EID2,ENG,FOLR1,FOXH1,GDF5,HPGD,MSTN,MTMR4,PBLD,PDE3A,PDGFD,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,SOX5,STAR,STK16,TAB1,TGFBR3,TP53,WNT5A,ZBTB7A |
| GO_REGULATION_OF_GROWTH | 0.0e+00 | 0.0e+00 | 1652 | 680 | 61 | ABL1,AGT,ALOX15B,APBB2,APOE,AR,ATRN,BCAR1,BMP4,CAPN3,CAV3,CDKL5,CISH,CXCL12,CYP27B1,DBNL,DLL1,EFNA5,ERBB2,GDF5,GPAM,H3-3A,HYAL1,IGFBP5,KAZALD1,KLHL22,LAMTOR1,MAP2K5,MEGF8,MEIS1,MSTN,NANOS1,NOG,NPR1,OPA3,PIN1,PLAC8,PLCB1,PLCE1,PPARD,ROS1,SELENOP,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SMARCA2,SOCS5,SPAAR,ST20,STAT3,TGFBR3,TLE5,TP53,TRIM46,TSPYL2,ULK2,VIL1,WFDC1,WNT5A |
| GO_HORMONE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 236 | 33 | ACE2,ALDH9A1,BMP5,CHST9,CPA3,CPE,CTSZ,CYP17A1,CYP27B1,CYP2C18,DDO,DKK3,DKKL1,FFAR3,GATA3,HFE,HSD17B1,MME,PCSK6,PCSK7,PLB1,PLEKHA1,RDH11,RDH14,REST,SERPINA6,STAR,SULT1A1,SULT1B1,SULT1E1,TRERF1,UGT2B11,VDR |
| GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 577 | 55 | ABL1,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,AZU1,BAD,BMP4,CALM3,CCND3,CCR7,CD4,DAG1,DBNL,DKK1,DOCK3,DUSP19,EFNA5,ERBB2,ETAA1,F2R,FGR,FPR1,GPRC5C,GRM1,IL6R,ITSN1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MTCP1,NEK10,PAK3,PAK6,PDE6G,PDGFC,PDGFD,PFKFB1,PIK3CB,PKD2,PLCE1,PRKCD,PRKD1,PTPRC,RAF1,RAPGEF2,STOX1,STRADA,TAB1,TAL1,TNFAIP8L3,WNT5A |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1652 | 737 | 64 | ABL1,ADAMTSL4,AGT,APBB2,ARHGEF17,ARL6IP5,ASCL1,AXIN2,B4GALT1,BACE1,BAD,BEX3,BMP4,BOK,CALCR,CD36,CNR1,COL18A1,CTLA4,CTSH,CTSZ,DKK1,DKKL1,DNMT3A,F2R,FGD3,FGD4,GPER1,HPGD,INPP5D,ITSN1,KMO,LRRK2,MAP3K11,NACC2,PAK3,PANO1,PDCD4,PIK3CB,PIN1,PIP5KL1,PLEKHF1,PLEKHG5,PRKCD,PRODH,PRR7,PSEN2,PTPA,PTPRC,RAPGEF2,RARG,REST,SMAD3,ST20,TCTN3,TLE5,TNFRSF10C,TNFSF12,TP53,TP63,TRIO,VDR,WNT5A,ZBTB16 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE | 0.0e+00 | 0.0e+00 | 1652 | 367 | 42 | ABL1,ACTR3B,APOE,ARPC5,ARPIN,CAV3,CCR7,CDKL5,CFL1,CXCL12,DBNL,EFNA5,F2RL1,FHOD3,FMN1,GMFB,KCNN4,LIMA1,LMOD1,MEGF8,NAA80,PAK3,PEX11A,PEX11B,PEX11G,PRKCD,PRR16,RARG,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLC12A9,SPTBN2,TMOD1,TMSB15B,TRIM46,TRIOBP,ULK2,VIL1,VILL,WNT5A |
| GO_DEPHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1652 | 479 | 49 | ALPP,CABIN1,CALM3,CD33,CPPED1,DMPK,DUSP19,DUSP28,EYA1,HACD2,IKBKB,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,LPIN3,MDP1,MTMR4,NSMF,NUDT16L1,PCIF1,PDP2,PFKFB1,PHLPP1,PHOSPHO2,PIN1,PPM1B,PPP1CB,PPP1R35,PPP6R2,PRKCD,PTPA,PTPN18,PTPN22,PTPRA,PTPRB,PTPRC,PTPRO,PTPRU,RCAN1,RCAN3,SGPP2,SMAD3,SSH3,STYX,TAB1,TNS2,WDR81 |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 353 | 41 | AASS,ABCD1,ACADL,ACCS,ACLY,ACSF3,ADI1,ALOX15B,AP2A1,APOC3,ASPG,BGN,CBR4,CHST14,CYP2E1,CYP7B1,DECR2,DPYD,ELOVL3,ELOVL5,FOLH1,GIP,GPT,HACD1,HACD2,HOGA1,HPGD,HSD3B7,HYAL1,KMO,KYAT1,LPGAT1,MGST2,OSBPL9,PTGDS,SCP2,SHMT1,SLC27A2,SLC35D1,STAR,TBXAS1 |
| GO_MONOCARBOXYLIC_ACID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 128 | 24 | ABCD1,ACAD10,ACADL,ACADS,AUH,BDH2,CEL,CNR1,CPT2,DECR2,ECHDC2,ECI2,ETFB,HADH,HOGA1,IDNK,IVD,LDHD,LPIN3,PEX13,PPARD,SCP2,SLC27A2,SLC27A4 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 534 | 52 | ABL1,ACTR3B,ARPC5,ARPIN,CAV3,CCR7,CELSR1,CEP70,CFL1,CXCL12,DBNL,EFNA5,EPHA1,EPHA5,F2RL1,FHOD1,FHOD3,FMN1,FSCN1,GMFB,GNAI1,GPM6B,INPP5J,KAT2B,LIMA1,LMOD1,MAPK3,NAA80,PAK3,PARP3,PHLDB1,PIK3R1,PKHD1,PLXNB1,PRKCD,RAC3,RASSF7,RHOBTB2,SEMA3E,SERPINF2,SMAD3,SPTBN2,SYNPO,TMOD1,TMSB15B,TPM1,TRIM37,TRIOBP,TRPM2,UBXN2B,VIL1,VILL |
| GO_EPITHELIAL_TUBE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 327 | 39 | ABL1,AGT,AR,BMP4,BMP5,CAV3,CCDC40,CELSR1,CFL1,CTSH,CTSZ,DAG1,DLG5,DLL1,EDNRA,ENG,ESRP2,EYA1,FMN1,FOLR1,FOXH1,FZD6,GATA3,IRX3,KLHL3,MEGF8,NOG,OSR1,PKD2,PLXNB2,RARG,RSPO2,SEMA3E,SHROOM3,SMAD3,STARD13,STOX1,VDR,WNT5A |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 622 | 57 | ABL1,AMOTL2,AP2A1,APCDD1,APOE,AXIN2,BMP4,C3,CACNB3,CELSR1,CELSR3,COL1A1,CPE,CUX2,DKK1,DKK3,DKKL1,DMPK,FOLR1,FZD6,GATA3,GNAQ,INVS,JRK,LRRK2,MCC,MITF,NLGN3,NOG,NOTUM,PDE6A,PDE6G,PIN1,PKD2,PLCB1,PPM1B,PTPRO,PTPRU,PYGO2,RARG,RBMS3,RNF213,RSPO2,SENP2,SMAD3,SPIN1,TAX1BP3,TBX18,TLE2,TLE5,TRABD2A,TRABD2B,TSKU,VAX2,WNT5A,ZBED3,ZRANB1 |
| GO_COAGULATION | 0.0e+00 | 0.0e+00 | 1652 | 343 | 40 | AK3,AKAP1,ANXA8,APOE,AXL,BLOC1S4,CD36,COL1A1,COL1A2,COL3A1,DGKA,DGKB,DOCK1,DOCK11,EHD2,F2R,F2RL1,FBLN1,FZD6,GATA3,GNA14,GNAQ,H3-3A,H3C6,HPS6,HPSE,MAPK3,MYL9,NFE2,PDPN,PIK3CB,PIK3R1,PLSCR1,PRKCD,RAF1,SERPINA5,SERPINF2,TLN1,TSPAN8,VWF |
| GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 242 | 33 | ABL1,BMP4,BMP5,CAV3,CDKN1C,CDKN2B,DAND5,DKK1,DKK3,EID2,ENG,FBXL15,FKBP8,FOLR1,FSTL1,GDF5,HFE,INHA,MSTN,MTMR4,NOG,PBLD,PCSK6,PIN1,PMEPA1,RASL11B,RBPMS,SMAD3,SNX25,TGFBR3,TP53,WNT5A,ZBTB7A |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1652 | 974 | 76 | ABCA7,ABL1,ACKR3,AGT,AJUBA,ANGPT1,APOE,AR,ARL6IP5,BMP4,BMP5,CALCR,CAV3,CCR7,CD36,CD4,CTSH,DAG1,DBNL,DKK1,DUSP19,ERBB2,F2R,F2RL1,FBLN1,FGF7,FPR1,GDF5,GFRA1,GPER1,GPR183,GRM1,HTR2C,IGF1R,IKBKB,INHA,KBTBD7,LAMTOR1,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MECOM,MSTN,NDST1,NEK10,PAK3,PAK6,PDCD4,PDE6G,PDGFC,PDGFD,PHLPP1,PIK3CB,PIK3R2,PIN1,PKHD1,PLCB1,PLCE1,PRKCD,PSCA,PTPN22,PTPRA,PTPRC,RAF1,RAPGEF2,ROS1,SERPINF2,SPTBN2,STRADA,STYX,TAB1,TNFAIP8L3,WNT5A |
| GO_MUSCLE_TISSUE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 406 | 44 | AGT,ALPK3,ANKRD2,BMP4,BMP5,BTG2,CASQ1,CAV3,COL3A1,DKK1,DLL1,ENG,EYA1,FHOD3,FOXH1,GPX1,IGFBP5,IGSF8,JPH2,KLHL41,MEIS1,MSTN,MYLK,MYOM1,MYOM3,NDUFV2,NEBL,NOG,NR2F2,OBSL1,OSR1,PIN1,PKD2,PPP1R13L,RIPOR2,RXRA,SELENON,SEMA3C,SMAD3,STRA6,TGFBR3,TNNC1,TPM1,WNT5A |
| GO_CELL_CELL_SIGNALING_BY_WNT | 0.0e+00 | 0.0e+00 | 1652 | 521 | 51 | ABL1,AMOTL2,AP2A1,APCDD1,APOE,AXIN2,CELSR1,CELSR3,COL1A1,CPE,DKK1,DKK3,DKKL1,FOLR1,FZD6,GATA3,GNAQ,INVS,JRK,LRRK2,MCC,MITF,NOG,NOTUM,PDE6A,PDE6G,PIN1,PKD2,PLCB1,PPM1B,PTPRO,PTPRU,PYGO2,RARG,RBMS3,RNF213,RSPO2,SENP2,SMAD3,SPIN1,TAX1BP3,TBX18,TLE2,TLE5,TRABD2A,TRABD2B,TSKU,VAX2,WNT5A,ZBED3,ZRANB1 |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 1567 | 105 | ABL1,ACTA2,ADARB1,AGBL4,AGBL5,APOBEC3C,APOBEC3G,APOE,APOL1,APPL2,AXL,AZU1,C1R,C1RL,C3,C4A,C4B,CADM1,CCDC80,CCR7,CD36,CD4,CFB,CFL1,CNR1,CR1,CRISP3,CRP,CTSS,CXCL12,CYBC1,CYP27B1,CYP2E1,DACH1,DEFB1,DGKB,EIF2AK4,ERBIN,F2R,F2RL1,FBXO9,FGR,FKBP5,FMO1,GATA3,GPAM,GPER1,GPX1,HEXIM1,HPGD,HYAL1,IFITM2,IFITM3,IGHV3-73,IKBKB,IKBKE,IL17RC,IL27RA,IL6R,JAGN1,JCHAIN,KMO,LDOC1,LYPD8,MAPK3,MAVS,MGST2,MMP12,MR1,MSRB1,MUC15,MYD88,NFIB,NLRX1,PAK3,PARP9,PDCD4,PLAC8,PLSCR1,PLSCR4,PPARD,PPM1B,PRKCD,PRKD1,PTGER2,PTPN22,PTPRC,RAF1,RARRES2,RBMS3,RTP4,SMAD3,SPARC,SSC5D,STAR,TAB1,TLR1,TMEM229B,TP53,TRIM22,TRIM29,TRIM59,VDR,VIL1,WNT5A |
| GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 302 | 37 | ABL1,ACTN4,APOE,BHLHB9,CDKL5,CFL1,CHN1,CUX2,CXCL12,DBNL,DOCK1,EFNA5,FBLN1,HECW2,LIMS2,LRRK2,MEGF8,NLGN3,NSMF,OBSL1,PAK3,PDPN,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRO,RAC3,RAPGEF2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,TRIOBP,ULK2,WNT5A |
| GO_CONNECTIVE_TISSUE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 274 | 35 | ACTA2,ADAMTS7,AXIN2,BGN,BMP1,BMP4,BMP5,COL12A1,COL14A1,COL1A1,CRIP1,EFEMP1,GDF5,HYAL1,IL6R,ITGB8,MAPK3,MGP,NFIB,NOG,OSR1,PDGFD,PKDCC,PPARD,RARG,RORC,RSPO2,SMAD3,SOX5,TGFBI,THRA,TRIP11,WNT5A,ZBTB16,ZNF219 |
| GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 194 | 29 | ACLY,ACSF3,ADI1,ANGPT1,B4GALT1,B4GALT6,BGN,CBR4,CHST14,CHST9,ELOVL3,ELOVL5,GSTA1,GSTA2,GSTM2,GSTT2B,HACD1,HACD2,MGST2,NDST1,NDST4,PDP2,SLC25A1,SLC26A1,SLC26A2,SLC35D1,ST3GAL3,ST3GAL6,TPK1 |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1652 | 567 | 53 | ABL1,AJUBA,ARL13A,ARMC4,BBOF1,CCDC151,CCDC28B,CCDC40,CCR7,CDKL5,CELSR3,CEP70,DBNL,DOCK11,F2RL1,FGD3,FGD4,FSCN1,ICK,IFT140,INPPL1,KLHL41,MAFIP,MSTN,MTSS2,MYLK,NINL,NPHP1,NUDCD3,PARVB,PKHD1,PLD1,PLXNB3,PRKCD,PTPRO,RABL2B,RAC3,RAPGEF2,RIPOR2,SEPTIN11,SPAG16,STK36,SYNE2,TBC1D32,TCTN3,TENM2,TMEM107,TMEM80,TRIP11,TRPM2,TTC30B,TTC39C,WDR60 |
| GO_EMBRYONIC_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 294 | 36 | BMP4,CCDC40,CELSR1,DLL1,EFEMP1,ENG,EYA1,FOLR1,FOXH1,FZD6,GATA3,HOXA4,HOXA7,HYAL1,IFT140,MAFB,MAPK3,MEGF8,NDST1,NOG,OSR1,PKD2,POU3F4,RARG,RIPOR2,SLITRK6,SMAD3,STOX1,STRA6,TRIOBP,TSHZ1,TTC39C,VAX2,WDR60,WNT5A,ZIC1 |
| GO_LEUKOCYTE_MIGRATION | 0.0e+00 | 0.0e+00 | 1652 | 502 | 49 | ADA,ANGPT1,ANGPT2,ANGPT4,AZU1,B4GALT1,BMP5,CCL28,CCR7,CD99L2,COL1A1,COL1A2,CXCL12,CXCR5,CYP7B1,F2RL1,GATA3,GCSAM,GPR183,GRB7,HOXA7,HSD3B7,IL17RC,IL1R1,IL27RA,IL6R,INPP5D,JAGN1,JCHAIN,MAPK3,MMP28,MSTN,OLR1,PADI2,PDGFD,PIK3CB,PIK3R1,PIK3R2,PLCB1,PPIL2,PSG1,PTPRO,RARRES2,RIPOR2,SLC7A7,TP53,TRPM2,VEGFB,WNT5A |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 1364 | 94 | ACKR1,ACKR3,ADA,ADCY6,ADGRF5,ADGRG1,ADGRG2,ADGRL3,AGT,APLN,APOC3,APOE,ARHGEF17,ARHGEF25,AZU1,BCAR1,C3,CALCR,CALM3,CCL28,CCR7,CELSR1,CELSR3,CISH,CNR1,CORT,CPE,CXCL12,CXCR5,DAGLA,DEFB1,DGKA,DGKB,DNM1,EDNRA,F2R,F2RL1,FFAR3,FGD3,FGD4,FPR1,FZD6,GIP,GNA14,GNAI1,GNAQ,GNAT3,GNG10,GPER1,GPR183,GPR39,GPRC5C,GRM1,HPGD,HTR2C,ITSN1,LPAR2,LPAR6,MC1R,MGRN1,NMB,NPB,NPR1,NPR3,OGFRL1,OPN3,OR1F2P,OR2T8,OR51E2,OR5A2,P2RY11,PDE1A,PDE3A,PDE6A,PDE6G,PDE7B,PDE8B,PIK3CB,PIK3R1,PLCB1,PLCE1,PLEKHG5,PLXNB1,PTGER2,RAMP1,RAPGEF2,RGS7BP,RLN3,RXFP1,TAS2R10,TRIO,VIPR1,WNT5A,ZNF219 |
| GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 504 | 49 | ABL1,ADCY6,AGT,AP2A1,APOE,BHLHB9,BMP5,CDKL5,CFL1,CHN1,CNR1,CSMD3,CTSZ,CUX2,CXCL12,DBNL,DGUOK,DKK1,DLG5,EFNA5,GATA3,HECW2,INPP5J,ITSN1,LRRK2,MEGF8,NCKIPSD,NLGN3,NSMF,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,PTPRO,RAPGEF2,RTN4RL1,SCARF1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,TRIM46,ULK2,WASHC5,WNT5A |
| GO_FATTY_ACID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 104 | 21 | ABCD1,ACAD10,ACADL,ACADS,AUH,BDH2,CEL,CNR1,CPT2,DECR2,ECHDC2,ECI2,ETFB,HADH,IVD,LPIN3,PEX13,PPARD,SCP2,SLC27A2,SLC27A4 |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 1652 | 1061 | 79 | ABCC6,ABL1,ADA,ADCY6,ADGRL3,AGT,ALDH3A1,ARL6IP5,ASCL1,ATP1A2,AXL,BAD,CALM3,CCR7,CLDN7,CNR1,COL18A1,COL1A1,CXCL12,CYGB,CYP2C18,CYP2E1,CYP4B1,DNMT3A,EFNA5,ENG,ENO3,ERBIN,FCSK,FOLR1,GATA3,GIP,GNA14,GNAI1,GNAQ,GNAT3,GPX1,GSTM2,HADH,HPGD,HTR2C,LDOC1,LRRK2,LYPD1,MAPK3,MB,MSTN,OSR1,P2RY11,PARP4,PDE3A,PDGFD,PLCB1,PLEKHA1,PMS2,PRKCD,PTGER2,PTPN22,RECQL5,REST,RHAG,SELENON,SEMA3C,SERPINF1,SLC13A4,SLC1A1,SLC22A5,SLC52A1,SPARC,STAR,STAT3,STRA6,SYT12,TCN2,TP53,TRPM2,TXN2,VEGFB,WFDC1 |
| GO_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 139 | 24 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,CBR4,DBI,ELOVL3,ELOVL5,GPAM,HACD1,HACD2,PANK1,PDP2,SLC25A1,SLC26A1,SLC26A2,SUCLG2,SULT1A1,SULT1B1,SULT1E1 |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1652 | 614 | 55 | ABL1,ADCY6,AR,ATP1A2,BMP4,COL1A1,CYP27B1,CYP7B1,DAG1,EFNA5,FAM210B,FOLR1,FOXH1,GDAP1,GNA14,GNAI1,GNAQ,GPAM,GPD1,GPER1,GSTM2,HTR2C,IGFBP5,KANK2,LRRK2,MAPK3,MAVS,MSTN,NR2F2,NR2F6,OR51E2,P2RY11,PADI2,PAK3,PDE3A,PKD2,PMEPA1,PPARD,RAPGEF2,RARG,RECQL5,REST,RORC,RXRA,SELENON,SERPINF1,SHMT1,STAR,STAT3,THRA,TP63,TRPM2,VDR,ZBTB7A,ZNF366 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 1741 | 111 | ABCD1,ACOT2,ACTN4,ACTR1B,AGT,ANGPT1,ANK2,ANXA8,ANXA8L1,AP2A1,AP5B1,APOE,APPL2,ARF3,ARF5,ASPSCR1,BLOC1S1,BLOC1S4,BLOC1S5,BMP4,CACNB3,CD36,CHMP6,COG8,COPZ2,CORO7,CPT2,CTSZ,DDO,DECR2,DMAC2L,DNAJC15,ECI2,EEA1,EHD2,ERBB2,ERBIN,ERGIC1,FAM53A,FGR,FHOD1,FLOT2,FOLR1,GAS1,GDAP1,HERC2,HOOK2,HSPA1L,ICK,IFT140,KCNIP3,LAMTOR1,LRRK2,MAPK3,MAVS,MGRN1,MMP12,MPPE1,NRBP2,PDZK1,PEX13,PIK3R1,PIK3R2,PRKCD,PURA,RAB11FIP3,RABL2A,RABL2B,RAMP1,RANBP3L,RASSF9,RBM15B,RTP4,SCP2,SEC16A,SLC27A2,SMAD3,SPG11,SPTBN2,STAR,STAT3,STRADA,STX10,STYX,SUN2,SYNE2,SYTL1,TBC1D2B,TBC1D5,TBC1D9,TMEM129,TNNC1,TOM1L2,TP53,TRAPPC2L,TRIM46,TRIP11,TTC30B,VAMP8,VPS13A,VPS13C,VPS28,VPS37D,VPS39,VPS41,WASHC5,WDR60,WDR81,ZDHHC12,ZDHHC21,ZIC1 |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 655 | 57 | ABL1,ADCY6,AGT,AJUBA,ANGPT1,ANGPT4,AZU1,BAD,BMP4,CALM3,CCND3,CCR7,CD4,DAG1,DBNL,DKK1,DOCK3,DUSP19,EFNA5,ERBB2,ETAA1,F2R,FGR,FPR1,GPRC5C,GRM1,IL6R,ITSN1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MTCP1,NEK10,PAK3,PAK6,PDE6G,PDGFC,PDGFD,PFKFB1,PIK3CB,PIN1,PKD2,PLAAT4,PLCE1,PRKCD,PRKD1,PTPRC,RAF1,RAPGEF2,STOX1,STRADA,TAB1,TAL1,TNFAIP8L3,WNT5A |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1652 | 1116 | 81 | ABL1,ADA,ANGPT1,APOE,APPL2,ARPC5,BCAR1,BTN3A3,C1R,C1RL,C3,C4A,C4B,CACNB3,CADM1,CCR7,CD33,CD36,CD4,CFB,CNR1,COL1A1,COL1A2,COL3A1,CR1,CRP,CTLA4,CTSH,CTSS,CUEDC2,DOCK1,EIF2AK4,ERBIN,F2RL1,FCGR2A,FFAR3,FGR,FPR1,GATA3,GCSAM,GPX1,HEXIM1,HFE,IGHV3-73,IKBKB,IKBKE,IL1R1,IL27RA,INPP5D,KCNN4,LAX1,LOXL3,MAPK3,MAVS,MMP12,MUC15,MYD88,NCKIPSD,NFAM1,NLRX1,PAK3,PARP3,PARP9,PIK3CB,PIK3R1,PIK3R2,PLEKHA1,PLSCR1,PRKCD,PTPN22,PTPRC,PVRIG,RAF1,SMAD3,SOCS5,SPPL2B,TAB1,TLR1,VAMP8,WNT5A,ZBTB7B |
| GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 499 | 48 | ABL1,AGT,ANK2,ATP1A2,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,CD33,CD4,CXCL12,CYP27B1,EFHB,F2R,GPER1,GRAMD2A,GSTM2,HTR2C,JPH2,KCNE3,KCNN4,MYLK,NALCN,NIPAL2,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,RAMP1,SELENON,SLC24A5,STAC2,STIM1,STIMATE,TCN2,TMC1,TPCN2,TRPC4,TRPM2,VDR,WNK3 |
| GO_INOSITOL_LIPID_MEDIATED_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 193 | 28 | AGT,ANGPT1,ENTPD5,ERBB2,F2R,F2RL1,FGR,GATA3,GPER1,IGF1R,MAPK3,NPR3,PDGFC,PDGFD,PIK3CB,PIK3R1,PIK3R2,PIP4K2B,PITPNM2,PLCB1,PLCD4,PLCE1,PLCH2,PLD1,PLEKHA1,PLXNB1,PPARD,TNFAIP8L3 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 292 | 35 | ABL1,AGT,APLN,BMP4,CAV3,CCBE1,CDKN1C,CDKN2B,CREB3L1,DAND5,DKK1,DKK3,DLL1,EID2,ENG,FBXL15,FKBP8,FOLR1,FSTL1,GATA3,GDF5,MTMR4,MYOF,NOG,PBLD,PCSK6,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,TGFBR3,TP53,WNT5A,ZBTB7A |
| GO_EPITHELIAL_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 207 | 29 | ACTA2,ADAMTSL4,AR,ARID4A,B4GALT1,BAD,BMP4,BMP5,COL18A1,DLL1,ENG,F2RL1,FRMD6,GPX1,IKBKB,LAMB2,MYO1E,RAPGEF2,RARG,RIPOR2,ROS1,SHROOM3,SIDT2,SLITRK6,TMC1,TMOD1,TP63,TRIOBP,WNT5A |
| GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 401 | 42 | ABL1,ADA,ADGRG1,ANGPT1,AZU1,BAD,CCDC80,CCL28,CCR7,CD36,CD4,CTLA4,CXCL12,DAG1,DOCK1,DPP4,EGFL6,EPHA1,ERBB2,FBLN2,FLOT2,FMN1,GATA3,GPAM,HYAL1,LIMS2,PAK3,PDPN,PIK3R1,PTPRC,PTPRU,RAC3,RNASE10,SERPINF2,SMAD3,SOCS5,TPM1,TRIOBP,UTRN,WNT5A,ZBTB16,ZBTB7B |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1652 | 1559 | 102 | ABCD1,ABL1,ACE2,ACKR3,ADA,AGT,AJUBA,APOBEC3G,APOE,APPL2,ARL6IP5,AXIN2,BAD,BOK,C3,CADM1,CAPN3,CAV3,CCR7,CD36,CNR1,CR1,CREB3L1,CTSS,CUEDC2,CXCL12,DBNL,DKK1,DUSP19,EFHD1,EIF2AK4,ERBIN,ETAA1,EYA1,F2R,F2RL1,FFAR3,FGR,GATA3,GPER1,GPX1,HEXIM1,HPSE,HSPA1L,IGF1R,IKBKB,IKBKE,IL17RC,IL1R1,LANCL1,LRRK2,MAP3K11,MAP3K12,MAPK3,MAVS,MECOM,MGST2,MLIP,MMP12,MUC15,MYD88,MYLK,NACC2,NLRX1,NUDT16L1,PAK3,PARP3,PARP9,PDCD4,PDPN,PHLPP1,PIK3R1,PLCB1,PLSCR1,PPARD,PPM1B,PRKCD,PTPN22,PTPRC,RAF1,RECQL5,REST,RTN4RL1,SCARF1,SELENON,SERPINF1,SERPINF2,SESN1,SMAD3,SOCS5,SPAAR,STOX1,TAB1,TLR1,TP53,TSPAN8,VAMP8,VIL1,VPS13C,WFDC1,WNT5A,ZBTB7B |
| GO_ENDOCYTOSIS | 0.0e+00 | 0.0e+00 | 1652 | 661 | 57 | ABCA7,ABL1,ACKR3,ACTN4,ANGPT1,ANK2,AP2A1,APLN,APOC3,APOE,APOL1,APPL2,AXL,C3,CACNG8,CALM3,CAV3,CD36,CEL,DBNL,DKK1,DLL1,DNM1,DOCK1,EEA1,EHD2,F2RL1,FOLR1,HFE,HOOK2,HSPG2,IGHV3-73,INPPL1,ITSN1,JCHAIN,LOXL3,LRP1B,LRRK2,MAPK3,MRC2,MYO1E,NLGN3,PIK3CB,PRKD1,RAMP1,RIN2,RUFY1,SBSPON,SCARF1,SCARF2,SPARC,SSC4D,SSC5D,TBC1D5,TMPRSS5,VPS28,WNT5A |
| GO_NEGATIVE_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 294 | 35 | ABL1,ACTN4,ANGPT1,ANGPT2,B4GALNT2,BMP4,CCL28,CLDN7,COL1A1,CTLA4,CXCL12,DLG5,EFNA5,ERBB2,FBLN1,HFE,HOXA7,LAX1,LOXL3,MAP2K5,MMP12,PIK3R1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKCD,PTPN22,PTPRC,PTPRO,RIPOR2,SEMA3E,SOCS5,TGFBI,ZBTB7B |
| GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 0.0e+00 | 0.0e+00 | 1652 | 209 | 29 | ABL1,ACTN4,ANGPT2,CCDC80,CCL28,CCR7,CD36,COL1A1,DAG1,DOCK1,EFNA5,EGFL6,EPHA1,FBLN1,FBLN2,FMN1,GPM6B,HOXA7,LIMS2,MMP12,PDPN,PIK3CB,PIK3R1,PTPRO,RAC3,SEMA3E,SMAD3,TRIOBP,UTRN |
| GO_GLAND_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 437 | 44 | ABL1,ADA,ALOX15B,APLN,AR,ASCL1,BMP4,CAV3,CCDC40,CDKN1C,CRIP1,CYP7B1,DAG1,DKK3,ESRP2,FGF7,GATA3,GPX1,HFE,IGFBP5,LIMS2,MAFB,MAPK3,NFIB,NOG,NTN4,PKD2,PYGO2,RAF1,RARG,RXRA,SEMA3C,SERPINA5,SERPINF1,SMAD3,STRA6,TGFBR3,THRA,TP63,USF2,VDR,WNT5A,ZBTB7B,ZDHHC21 |
| GO_CARTILAGE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 210 | 29 | ADAMTS7,AXIN2,BGN,BMP1,BMP4,BMP5,COL12A1,COL14A1,COL1A1,EFEMP1,GDF5,HYAL1,ITGB8,MAPK3,MGP,NFIB,NOG,OSR1,PKDCC,RARG,RSPO2,SMAD3,SOX5,TGFBI,THRA,TRIP11,WNT5A,ZBTB16,ZNF219 |
| GO_GLYCOSYLATION | 0.0e+00 | 0.0e+00 | 1652 | 267 | 33 | ALG6,ALG9,B3GALT4,B3GLCT,B3GNT10,B4GALNT2,B4GALT1,B4GALT6,DOLK,DPM3,DPY19L4,EDEM3,ENTPD5,EXT2,EXTL1,FUT11,GALNT5,MGAT4B,MGAT4C,MUC15,PIGB,POMT1,RAMP1,ST3GAL3,ST3GAL6,ST6GALNAC2,ST6GALNAC5,ST6GALNAC6,TMTC1,TMTC4,TRIP11,VEGFB,XXYLT1 |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 704 | 59 | ADCY6,AGT,APPL2,AR,ATP1A2,ATP6V0A4,BCAR1,BMP4,CCND3,CTSH,CTSS,CYP7B1,EFNA5,EIF4EBP2,FAM210B,FFAR3,FOXH1,GNAQ,GPAM,GPER1,IGF1R,KANK2,KAT2B,LEPR,LPIN3,LYPD1,MSTN,NCOA5,NR2F2,NR2F6,NSMF,OR51E2,PADI2,PIK3R1,PIK3R2,PIK3R3,PLCB1,PMEPA1,PPARD,PRKCD,PTGER2,PTPRA,RAMP1,RARG,RARRES2,REST,RORC,RXFP1,RXRA,SERPINF1,SLC2A8,STAR,STAT3,THRA,TP63,VDR,ZBTB7A,ZBTB7B,ZNF366 |
| GO_LIPID_OXIDATION | 0.0e+00 | 0.0e+00 | 1652 | 101 | 20 | ABCD1,ACAD10,ACADL,ACADS,APPL2,AUH,BDH2,CNR1,CPT2,CYGB,DECR2,ECHDC2,ECI2,ETFB,HADH,IVD,PEX13,PPARD,SCP2,SLC27A2 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1652 | 526 | 49 | ABL1,ACE2,ACTR3B,ADGRL3,AGT,AJUBA,ARPC5,ARPIN,BHLHB9,CAV3,CCR7,CD36,CUX2,DAG1,DLG5,DOCK11,EFNA5,EPHA1,ERCC5,F2RL1,FHOD1,FLRT3,FMN1,FSCN1,GMFB,GTF2H5,HYAL1,JCHAIN,LMOD1,LRRC24,MSTN,NLGN3,NPHP1,PAN2,PHLDB1,PIP4K2B,RIPOR2,SEMA4A,SERPINF2,SLITRK6,SMAD3,SYNPO,TAL1,TENM2,TP53,TPM1,TRABD2A,TRABD2B,VIL1 |
| GO_POSITIVE_REGULATION_OF_ENDOCYTOSIS | 0.0e+00 | 0.0e+00 | 1652 | 101 | 20 | ABCA7,ACTN4,ANGPT1,AP2A1,APLN,APOE,APPL2,AXL,C3,CAV3,CD36,DLL1,DNM1,F2RL1,HFE,ITSN1,LRRK2,TBC1D5,VPS28,WNT5A |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 526 | 49 | ADA,AGL,ALDH3A1,APOE,APPL2,ASCL1,AXL,CACNB3,CADPS2,CCL28,CD4,CDKN2B,CNR1,COL1A1,CYP27B1,DNAJC15,DNMT3A,EIF2AK4,FOLR1,FSTL1,GDAP1,GIP,HFE,HTR2C,KANK2,LRRK2,MAP1LC3C,MAPK3,MIOS,MMP7,NNT,OMA1,P2RY11,PFKFB1,PPARD,PRKD1,PTPRC,RNF152,SESN1,SLC27A4,SPARC,STAR,TBC1D5,TLE5,TP53,TXN2,ULK2,USF2,VDR |
| GO_FATTY_ACID_BETA_OXIDATION | 0.0e+00 | 0.0e+00 | 1652 | 71 | 17 | ABCD1,ACAD10,ACADL,ACADS,AUH,BDH2,CNR1,CPT2,DECR2,ECHDC2,ECI2,ETFB,HADH,IVD,PPARD,SCP2,SLC27A2 |
| GO_AMEBOIDAL_TYPE_CELL_MIGRATION | 0.0e+00 | 0.0e+00 | 1652 | 462 | 45 | ABL1,AGT,AMOTL2,ANGPT1,ANGPT2,ANGPT4,APOE,APPL2,ATOH8,BCAR1,BMP4,CCBE1,CFL1,CTSH,CYGB,DOCK1,DPP4,FAT2,FGF7,FOLR1,GATA3,GPX1,HYAL1,KANK2,MAP2K5,MCC,MEGF8,NANOS1,NR2F2,PAK3,PBLD,PIK3R3,PLEKHG5,PPARD,PRKD1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SPARC,STARD13,TNFSF12,VIL1,WNT5A |
| GO_SYNAPTIC_SIGNALING | 0.0e+00 | 0.0e+00 | 1652 | 733 | 60 | ABL1,ADARB1,AGT,APOE,ATP1A2,BACE1,CACNB3,CADPS2,CALM3,CEL,CNR1,CNTNAP4,CORT,CUX2,DAG1,DAGLA,DGKB,DKK1,DMPK,DNM1,EIF2AK4,EIF4EBP2,F2R,GIP,GNAI1,GNAQ,GPER1,GRM1,HTR2C,IQSEC2,KMO,LRRK2,LYNX1,LYPD1,MME,NLGN3,NSMF,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PDE7B,PLCB1,PLEKHG5,PNKD,PRR7,PTPRA,RAC3,RAPGEF2,SCN2B,SLC1A1,SNCAIP,SPG11,STAR,STAT3,SV2A,SYN2,SYNPO,SYT12,UNC13C |
| GO_COLLAGEN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 115 | 21 | ADAMTS2,BMP4,COL15A1,COL1A1,COL1A2,CREB3L1,CTSS,CYGB,ENG,F2R,MMP12,MMP2,MMP25,MMP28,MMP7,MRC2,P3H2,PPARD,SERPINF2,TNS2,VPS33B |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 791 | 63 | ACKR1,ACKR3,ACTN4,AGPAT1,ANGPT1,APPL2,AXL,BAD,CCR7,CD36,CD4,CFL1,CISH,CNN2,COL1A2,CXCL12,CXCR5,DOK1,F2RL1,FPR1,FSCN1,GATA3,GSTA2,H3C6,IFITM2,IFITM3,IKBKB,IKBKE,IL17RC,IL17RE,IL1R1,IL1RAPL2,IL27RA,IL6R,INPP5D,INPPL1,JAGN1,LEPR,MAOA,MAPK3,MAVS,MMP12,MMP2,MYD88,PADI2,PARP9,PDCD4,PIAS3,PIK3CB,PIK3R1,PLCB1,PRKCD,PTPRC,RORC,SOCS5,SPPL2B,STAT3,TAB1,TNFRSF25,TNFSF12,TP53,TRIM22,WNT5A |
| GO_PEPTIDE_SECRETION | 0.0e+00 | 0.0e+00 | 1652 | 641 | 55 | ABL1,AGT,ALOX15B,ANGPT1,APLN,APOE,BAD,CADM1,CCR7,CD33,CD36,CNR1,CPE,CRP,DPP4,EFNA5,EPHA5,F2R,F2RL1,FFAR3,FGR,GATA3,GIP,GPAM,GPER1,HADH,HFE,HMGN3,HTR2C,IL17RC,IL27RA,ITSN1,JAGN1,KCNN4,LAX1,LRRK2,MAPK3,MAVS,MMP12,MTTP,MYO18A,MYOM1,OR51E2,ORM1,PPARD,PTPN22,RAB11FIP3,RAF1,REST,SIDT2,SSC5D,STEAP3,TLR1,WNT5A,ZBTB7B |
| GO_CELL_GROWTH | 0.0e+00 | 0.0e+00 | 1652 | 483 | 46 | ABL1,AGT,APBB2,APOE,BCAR1,CAV3,CDKL5,CISH,CXCL12,CYP27B1,DBNL,EFNA5,EIF2AK4,ERBB2,FLRT3,H3-3A,HYAL1,IGFBP5,KAZALD1,KLHL22,LAMB2,LAMTOR1,MAP2K5,MEGF8,NANOS1,NLGN3,NPR1,PIN1,PLCE1,PPARD,RARG,ROS1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SMARCA2,SPG11,ST20,TP53,TRIM46,TSPYL2,ULK2,WFDC1,WNT5A |
| GO_COFACTOR_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 449 | 44 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ALDH1L1,BDH2,CBR4,CIAO3,COQ9,CPOX,DBI,ELOVL3,ELOVL5,FOLH1,FOLR1,GCHFR,GPAM,GPX1,GSTA1,GSTA2,GSTM2,GSTT2B,HACD1,HACD2,KMO,MCCC1,MGST2,NNT,NUBPL,NUDT12,NUDT13,PANK1,PARP9,PDP2,SHMT1,SLC25A1,STAT3,SUCLG2,TCN2,TPK1 |
| GO_PHOSPHATIDYLINOSITOL_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 116 | 21 | ARF3,DPM3,HTR2C,INPP5D,INPP5J,INPPL1,MPPE1,MTMR4,PIGB,PIGQ,PIGS,PIGT,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PITPNM2,PITPNM3,PLEKHA1,RUFY1 |
| GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 0.0e+00 | 0.0e+00 | 1652 | 537 | 49 | ABL1,ACTN4,ACTR1B,ANK2,ATP1A2,BAD,BLOC1S1,BLOC1S4,BLOC1S5,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CCR7,CD4,CHMP6,CTSZ,DNM1,EFNA5,EPHA5,F2R,FHOD1,FOLR1,GPER1,GSTM2,HFE,HMGN3,HTR2C,JAGN1,JPH2,LRRK2,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PTPRC,RAF1,SEC16A,SELENON,SIDT2,SPG11,TPCN2,TRAPPC2L,TRIM46,TRIP11,TRPM2,UBXN2B |
| GO_MESENCHYME_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 276 | 33 | ACTA2,ACTG2,AXIN2,BMP4,BMP5,CFL1,COL1A1,DAG1,DAND5,DLG5,EDNRA,ENG,FBXL17,FOLR1,FOXH1,LOXL3,MAPK3,MCRIP1,NOG,OSR1,PBLD,PDCD4,PDPN,PHLDB1,PKD2,RANBP3L,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,TGFBR3,WNT5A |
| GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 573 | 51 | ABL1,ACTN4,AGT,ANK2,APPL2,ARL6IP5,ASPSCR1,ATP1A2,C3,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CLCNKA,CLIC3,CTSS,EDNRA,F2R,FXYD3,GIP,GPER1,GSTM2,HECW2,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KLF15,NALCN,NLGN3,OSR1,PDZK1,PIK3R1,PKD2,PSEN2,SCN1A,SCN2B,SELENON,STAC2,STIM1,STIMATE,TMC1,TPCN2,UTRN,WNK3 |
| GO_MAINTENANCE_OF_LOCATION | 0.0e+00 | 0.0e+00 | 1652 | 338 | 37 | ABL1,ANK2,APOE,ATP1A2,C3,CALM3,CAPN3,CASQ1,CCR7,CD36,CD4,CRP,DAG1,DAND5,F2R,GPER1,GSTM2,HTR2C,IKBKE,JPH2,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PPARD,PTPRC,SELENON,SUN2,SYNE2,TLN1,TMSB15B,TPCN2,TRPM2,TTC39B,VPS13A,VPS13C |
| GO_REGIONALIZATION | 0.0e+00 | 0.0e+00 | 1652 | 354 | 38 | ADGRG1,AR,ASCL1,AXIN2,BMP4,BTG2,C3,CELSR1,DKK1,DLL1,EN1,FBXL15,FKBP8,FOXH1,HOXA4,HOXA7,HOXC13,IFT140,IRX3,MAFB,MEGF8,NOG,NR2F2,OSR1,PCSK6,RARG,SEMA3C,SENP2,SMAD3,TBC1D32,TBX18,TMEM107,TP53,TP63,TSHZ1,VAX2,WNT5A,ZBTB16 |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1652 | 1864 | 114 | ABL1,ACTR1B,ADARB1,AJUBA,ALOX15B,ANAPC11,ANAPC13,ANAPC16,ANGEL2,APBB2,APPL2,ASCL1,AXIN2,BLCAP,BMP4,BRINP3,BTG2,CABLES1,CALM3,CAPN3,CCDC69,CCND3,CDK15,CDKL5,CDKN1C,CDKN2B,CEP70,CFL1,CHMP6,CNOT11,CUL9,CXCR5,CYP27B1,DACH1,DNMT3A,EID1,EIF2AK4,ETAA1,FBXL15,FBXL22,GAS1,GATA3,GNAI1,GPER1,HECW2,HEXIM1,HEXIM2,HPGD,HYAL1,INHA,INTS3,KANK2,KAT14,KAT2B,KDM8,KLHL22,LAMTOR1,LMLN,MAPK3,MDC1,MECOM,MPLKIP,MRPL41,NACC2,NEK10,NINL,NR2F2,OBSL1,PARP3,PBRM1,PCBP4,PDCD4,PDE3A,PIN1,PKD2,PKHD1,PLCB1,POGZ,PPP1CB,PRKCD,PTPA,PTPRC,RAB11FIP3,RBL2,RECQL5,REEP3,RTKN,SENP2,SEPTIN11,SEPTIN8,SLC2A8,SMAD3,SPIN1,SPIN2B,STAT3,STEAP3,STOX1,STRADA,SUN2,TAL1,TDRD9,TGM1,TNKS1BP1,TOM1L2,TP53,TRIM37,TRIOBP,TSPYL2,TTC28,TUBA3E,UBXN2B,USP22,WASHC5,WNT5A |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 724 | 59 | ABCA7,ACTN4,ADCY6,APOC3,APOE,AR,ARPIN,ATAD2B,BCOR,BMP4,BOK,CAV3,CLDN7,CTSZ,DGUOK,DKK1,DNAJC15,DPP4,EFNA5,FBLN1,FHOD3,GMFB,GPX1,H3-3A,IKBKB,INPP5J,KAT2B,KLHL22,LIMA1,LMOD1,LRRK2,NLGN3,OMA1,PLXNB3,PMEPA1,PRKCD,PRKD1,PRMT6,PTPRO,RAF1,RAPGEF2,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPTBN2,THRA,TMOD1,TMSB15B,TOM1L2,TP53,TRIM37,TRIM46,TRIOBP,ULK2,VIL1,VILL,WNT5A |
| GO_ANION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 294 | 34 | ABCD1,AGT,ANO2,ANO8,APOL1,ARL6IP5,ATP1A2,BEST2,BEST4,CLCA2,CLCNKA,CLIC3,CPT2,EMB,FOLR1,FXYD3,OSR1,PDPN,SLC12A9,SLC13A4,SLC16A7,SLC1A1,SLC20A2,SLC24A5,SLC25A1,SLC26A1,SLC26A2,SLC35D1,SLC37A2,SLC38A10,SLC4A2,SLC7A7,SLC9A9,STRA6 |
| GO_MEMBRANE_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 207 | 28 | ALDH3B1,ARSA,ASAH1,B3GALT4,B4GALT6,CERK,CERS6,DPM3,ELOVL3,ELOVL5,HACD1,HACD2,ITGB8,MGST2,MPPE1,PIGB,PIGQ,PIGS,PIGT,PRKCD,PRKD1,SGPP2,SPTSSA,ST3GAL6,ST6GALNAC5,ST6GALNAC6,STS,SUMF1 |
| GO_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 107 | 20 | ABCD1,ACADL,ACOT1,ACOT2,ALOX15B,CYP2C18,CYP2E1,DAGLA,ELOVL3,ELOVL5,GSTA1,GSTM2,HPGD,MAPK3,PNPLA3,PTGDS,SCP2,SLC27A2,SLC27A4,TBXAS1 |
| GO_HEART_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 295 | 34 | ACE2,ADA,AGT,ANK2,APLN,ATP1A2,ATP1A4,CACNB3,CACNG8,CALM3,CASQ1,CAV3,CTNNA3,DMPK,FXYD3,GPX1,GSTM2,HSPB7,KCNE3,KCNE4,KCNIP3,KCNJ3,KCNK15,NPR1,PPP1R13L,SCN1A,SCN2B,SLC1A1,STIM1,THRA,TNNC1,TNNI2,TPM1,VEGFB |
| GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1652 | 208 | 28 | AGGF1,APLN,AR,B4GALT1,BAD,BMP4,BMP5,CXCL12,CYP7B1,ERBB2,ESRP2,EYA1,FGF7,HYAL1,LAMB1,MAP2K5,MMP12,NOG,OSR1,PLXNB3,PRKD1,STAT3,STOX1,TGM1,TNFSF12,TP63,VEGFB,WNT5A |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1652 | 960 | 71 | ABL1,ADA,ADGRG1,AGGF1,AGT,ALDH3A1,APLN,AR,ASCL1,B4GALT1,BAD,BMP4,BMP5,CAV3,CD4,CLDN7,COL18A1,CRIP2,CTSH,CTSZ,CXCL12,CYP7B1,DLL1,DPP4,EPHA1,ERBB2,ESRP2,EYA1,F2R,FGF7,GPAM,GPER1,GPR183,HPGD,HPSE,HYAL1,IGF1R,IGFBP5,IL6R,LAMB1,MAP2K5,MARCKSL1,MMP12,MMP2,NACC2,NMB,NOG,OSR1,PDGFC,PDGFD,PKHD1,PLAC8,PLXNB3,POU3F3,PPARD,PRKD1,PTPRC,PURA,RARG,SELENON,SERPINF2,STAT3,STOX1,TGFBR3,TGM1,TNFSF12,TNS3,TP63,VEGFB,VIPR1,WNT5A |
| GO_REGULATION_OF_PEPTIDE_SECRETION | 0.0e+00 | 0.0e+00 | 1652 | 511 | 47 | ABL1,ALOX15B,ANGPT1,APLN,APOE,BAD,CADM1,CCR7,CD33,CNR1,CRP,DPP4,EFNA5,EPHA5,F2R,F2RL1,FFAR3,FGR,GATA3,GIP,GPAM,GPER1,HADH,HFE,HMGN3,HTR2C,IL17RC,IL27RA,ITSN1,JAGN1,KCNN4,LRRK2,MAPK3,MAVS,MMP12,MYO18A,MYOM1,OR51E2,ORM1,PPARD,PTPN22,RAB11FIP3,REST,SIDT2,SSC5D,TLR1,WNT5A |
| GO_SEXUAL_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1652 | 847 | 65 | ADA,ADAM21,ADAMTS2,ADGRG2,ANGPT2,AR,ARID4A,ATP1A4,AXL,B4GALT1,BAD,BMP4,C9orf24,CADM1,CCDC87,CNR1,DDO,DEFB1,DKKL1,DNMT3A,GLIPR1L1,H3-3A,HERC2,HPGD,HSPA1L,IGSF8,KLHL10,LEPR,LIMK2,LRRK2,NPHP1,NR2F2,PDE3A,PLB1,PLCB1,PLCD4,PLEKHA1,PYGO2,RNASE10,ROS1,SELENOP,SERPINA5,SIX5,SLC2A14,SLC2A8,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,SPIN1,SPIN2B,STAT3,TDRD9,THRA,TMEM203,TOB2,TP63,TSNAXIP1,TSPAN8,TUT4,VCX,WASHC5,ZBTB16,ZNF541 |
| GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 0.0e+00 | 0.0e+00 | 1652 | 549 | 49 | ACLY,ACTR1B,AGL,ALDH3B1,ANPEP,ARPC5,ARSA,ASAH1,ATP8B4,AZU1,B4GALT1,C3,CD33,CD36,CNN2,CPPED1,CR1,CRISP3,CRISPLD2,CTSH,CTSS,CTSZ,DBNL,F2RL1,FCGR2A,FGR,FPR1,HGSNAT,HPSE,JAGN1,LAMTOR1,MAVS,METTL7A,MME,MMP25,NFAM1,OLR1,ORM1,PADI2,PLAC8,PLD1,PRKCD,PTPRB,PTPRC,SERPINA3,SLC27A2,TMEM63A,TRPM2,VAMP8 |
| GO_CELLULAR_LIPID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 212 | 28 | ABCD1,ACAD10,ACADL,ACADS,AOAH,APOC3,ASAH1,AUH,BDH2,CEL,CNR1,CPT2,DAGLA,DECR2,ECHDC2,ECI2,ETFB,HADH,IVD,LPIN3,MGST2,PEX13,PNPLA3,PPARD,PRKCD,SCP2,SLC27A2,SLC27A4 |
| GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1652 | 483 | 45 | ABCA12,ABCA4,ACADL,ACOT11,ADCY6,ADGRF5,APLN,APPL2,CD36,CNR1,CPT2,CTSH,DLL1,ELOVL3,F2R,GPX1,HADH,HFE,IGF1R,INPP5D,IRX3,JCHAIN,KLHL10,LEPR,LNPEP,NANOS1,NPR3,OMA1,PBLD,PCDH15,PDGFC,PLAC8,PPP1R13L,RAC3,RHAG,SCNN1B,SERPINA3,SLC22A5,STAT3,THRA,TNS2,TP63,TRPM2,UCP2,ZBTB7B |
| GO_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1652 | 835 | 64 | ARL13A,ARMC4,BBOF1,CAPN3,CASQ1,CAV3,CCDC151,CCDC28B,CCDC40,CCDC69,CCDC78,CDKL5,CELSR3,CEP70,CHMP6,DBNL,FHOD3,FSCN1,GRB7,ICK,IFT140,KAT2B,KLHL41,LDB3,LMOD1,LRRK2,MAFIP,MAP1LC3C,MYOM1,MYOM3,NEBL,NINL,NPHP1,NUDCD3,OBSL1,PAN2,PIP4K2B,PKHD1,POGZ,RABL2B,SEPTIN11,SPAG16,SPG11,STK36,SYNE2,SYNPO,TBC1D32,TCTN3,TMEM107,TMEM80,TMOD1,TPM1,TRIM37,TRIP11,TTC30B,TTC39C,UBXN2B,ULK2,VCX,VIL1,VPS28,VPS37D,WASHC5,WDR60 |
| GO_MEMBRANE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1652 | 875 | 66 | ABCA4,ABCA7,ABCD1,ANK2,AP2A1,APOE,APPL2,AR,ARPC5,ATP8B4,BAD,BOK,C3,CALM3,CAV3,CAVIN2,CD36,CD4,CEL,CHMP6,CNTNAP2,CTSZ,DMAC2L,DMPK,DNM1,DOCK1,EEA1,EHD2,F2RL1,FLOT2,FOLR1,GLDN,GPER1,IGHV3-73,ITSN1,KCNN4,MOSPD3,MTSS2,MYO18A,MYOF,NLGN3,OMA1,PLSCR1,PLSCR4,PRKCD,PTPRC,REEP3,RTP4,SEC16A,SEPTIN8,SERPINA5,SLC2A8,SPG11,STAT3,STX10,SUN2,TIE1,TP53,TP63,TRAPPC2L,UBXN2B,VAMP8,VPS33B,VPS39,VPS41,WNT5A |
| GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1652 | 895 | 67 | ABL1,ADA,APPL2,ARPC5,BCAR1,BTN3A3,C1R,C1RL,C3,C4A,C4B,CACNB3,CADM1,CCR7,CD36,CD4,CFB,CNR1,CR1,CRP,CTLA4,CTSS,DOCK1,EIF2AK4,ERBIN,F2RL1,FCGR2A,FFAR3,FGR,FPR1,GATA3,GCSAM,HEXIM1,HFE,IGHV3-73,IKBKB,IKBKE,IL1R1,IL27RA,INPP5D,KCNN4,LAX1,MAPK3,MAVS,MMP12,MUC15,MYD88,NCKIPSD,NFAM1,NLRX1,PAK3,PARP9,PIK3CB,PIK3R1,PIK3R2,PLEKHA1,PLSCR1,PRKCD,PTPN22,PTPRC,PVRIG,RAF1,SOCS5,TAB1,TLR1,VAMP8,WNT5A |
| GO_PROTEIN_DEPHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1652 | 320 | 35 | CABIN1,CALM3,CD33,CPPED1,DMPK,DUSP19,DUSP28,EYA1,HACD2,IKBKB,MDP1,MTMR4,NSMF,PDP2,PHLPP1,PIN1,PPM1B,PPP1CB,PPP1R35,PPP6R2,PRKCD,PTPA,PTPN18,PTPN22,PTPRA,PTPRB,PTPRC,PTPRO,PTPRU,RCAN1,RCAN3,SSH3,STYX,TAB1,TNS2 |
| GO_MESENCHYMAL_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1652 | 216 | 28 | AXIN2,BMP4,BMP5,CFL1,COL1A1,DAG1,DLG5,EDNRA,ENG,FBXL17,FOLR1,LOXL3,MAPK3,MCRIP1,NOG,OSR1,PBLD,PDCD4,PDPN,PHLDB1,RANBP3L,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,TGFBR3,WNT5A |
| GO_RESPONSE_TO_OXIDATIVE_STRESS | 0.0e+00 | 0.0e+00 | 1652 | 453 | 43 | ABCD1,ABL1,ADA,ALDH3B1,ANKRD2,APOE,ARL6IP5,ATRN,AXL,BAD,CCR7,CD36,COL1A1,CYGB,CYP2E1,GPX1,GPX8,HYAL1,LANCL1,LRRK2,MAPK3,MB,MMP2,MSRB2,NEIL1,PDGFD,PDLIM1,PKD2,PLEKHA1,PRKCD,PRKD1,PRODH,RBPMS,REST,SELENON,SELENOP,SESN1,STAR,STOX1,TP53,TPM1,TRPM2,TXN2 |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 0.0e+00 | 0.0e+00 | 1652 | 650 | 54 | ACLY,ACTR1B,ADGRF5,AGL,ALDH3B1,ANPEP,ARPC5,ARSA,ASAH1,ATP8B4,AZU1,B4GALT1,C3,CD33,CD36,CNN2,CNR1,CPPED1,CR1,CRISP3,CRISPLD2,CTSH,CTSS,CTSZ,DBNL,F2RL1,FCGR2A,FGR,FPR1,HGSNAT,HPSE,LAMTOR1,LRRK2,METTL7A,MME,MMP25,MYO18A,NFAM1,OLR1,ORM1,PADI2,PLAC8,PLD1,PLSCR1,PRKCD,PTPRB,PTPRC,SERPINA3,SLC27A2,TLR1,TMEM63A,TRPM2,VAMP8,WNT5A |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 1146 | 79 | AASS,ABCA7,ABCD1,ABHD4,ACE2,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ALDH1L1,ANPEP,APOE,ASAH1,B3GALT4,B4GALT6,BACE1,BDH2,BTG2,CBR4,CERK,CERS6,CNOT11,CPA3,CPE,CTSH,CTSZ,DBI,EIF2AK4,EIF4EBP2,EIF4G3,ELOVL3,ELOVL5,ERBB2,FOLH1,FOLR1,GPAM,GPX1,GRB7,GSTA1,GSTA2,GSTM2,GSTT2B,HACD1,HACD2,IARS2,IGFBP5,ITGB8,LNPEP,MAPK3,MCCC1,MGST2,MME,MRPL41,NANOS1,PCIF1,PCSK6,PCSK7,PDP2,PIN1,PLAAT2,PLAAT4,PRKCD,PRR16,PSEN2,PURA,PYM1,RBMS3,RPL39P5,RXRA,SHMT1,SLC25A1,SPTSSA,ST6GALNAC5,ST6GALNAC6,STAT3,SUCLG2,ZC3H12D |
| GO_REGULATION_OF_SECRETION | 0.0e+00 | 0.0e+00 | 1652 | 824 | 63 | ABL1,ADA,AGT,ALOX15B,ANGPT1,APLN,APOE,BACE1,BAD,CADM1,CADPS2,CALM3,CCR7,CD33,CNR1,CRP,CXCL12,DPP4,EFNA5,EPHA5,F2R,F2RL1,FFAR3,FGR,GATA3,GIP,GPAM,GPER1,HADH,HFE,HMGN3,HTR2C,IL17RC,IL27RA,INHA,ITSN1,JAGN1,KCNN4,KMO,LRRK2,MAPK3,MAVS,MMP12,MYO18A,MYOM1,NMB,NPR1,OR51E2,ORM1,PNKD,PPARD,PTPN22,RAB11FIP3,REST,SIDT2,SNCAIP,SSC5D,SV2A,SYT12,TLR1,VAMP8,WNK3,WNT5A |
| GO_RESPONSE_TO_PEPTIDE | 0.0e+00 | 0.0e+00 | 1652 | 525 | 47 | ADCY6,AGT,APPL2,ATP6V0A4,BACE1,BCAR1,BTG2,CALCR,CCND3,CD36,COL1A1,CXCL12,DAG1,DNM1,EIF4EBP2,ERBIN,FFAR3,GIP,GNAI1,GPER1,HADH,IGF1R,IGFBP5,INPPL1,KAT2B,KLF15,LDOC1,LPIN3,MMP12,MMP2,MSTN,NCOA5,PFKFB1,PIK3R1,PIK3R2,PIK3R3,PRKCD,PTPN22,PTPRA,RARRES2,SLC2A8,SPARC,STAR,STAT3,TGFBR3,TP53,ZBTB7B |
| GO_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 233 | 29 | ABCD1,ACADL,ACCS,ACLY,ACSF3,ALOX15B,APOC3,BGN,CBR4,CHST14,CYP2E1,CYP7B1,DECR2,ELOVL3,ELOVL5,GIP,HACD1,HACD2,HOGA1,HPGD,HSD3B7,KMO,LPGAT1,OSBPL9,PTGDS,SCP2,SLC27A2,STAR,TBXAS1 |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 562 | 49 | ABL1,AGT,AP2A1,APOE,ASCL1,BAD,BHLHB9,BMP4,BMP5,BRINP3,CDKL5,CNR1,CUX2,CXCL12,DAG1,DBNL,DKK1,DLG5,DOCK1,EFNA5,FAIM,GDF5,GPER1,IRX3,ITSN1,LIMS2,MEGF8,MME,NCKIPSD,NSMF,OBSL1,PAK3,PDE3A,PIN1,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,RAC3,RAPGEF2,REST,SCARF1,SEMA3C,SERPINF1,STAR,TRIOBP,WASHC5,WNT5A |
| GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1652 | 204 | 27 | ABL1,ADGRG1,APOC3,APOE,ARHGEF17,ARHGEF25,CELSR1,CFL1,COL1A2,COL3A1,F2R,F2RL1,FGD3,FGD4,ITSN1,KANK2,LPAR6,PDPN,PLEKHG5,PLEKHG6,RAC3,RAF1,RHOBTB2,RIPOR2,RTKN,TAX1BP3,TRIO |
| GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 234 | 29 | ABL1,ADGRL3,APOE,BHLHB9,CDKL5,CFL1,CTTNBP2,CUX2,DAG1,DBNL,DGKB,DKK1,DLG5,DMPK,DNM1,EFNA5,FLRT3,IL1RAPL2,ITSN1,LRRC24,LRRK2,NLGN3,PAK3,PTPRO,SEMA4A,SEPTIN11,SLITRK6,SPARC,WNT5A |
| GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 72 | 16 | ABL1,ANK2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,F2R,GPER1,GSTM2,JPH2,KCNE3,PKD2,STAC2,STIM1,STIMATE |
| GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1652 | 548 | 48 | ABCA7,ABL1,ACKR3,AJUBA,ANGPT1,APOE,AR,ARL6IP5,BMP4,CALCR,CCR7,CD36,CD4,DBNL,DKK1,DUSP19,ERBB2,F2R,F2RL1,FPR1,GPER1,GPR183,GRM1,HTR2C,IGF1R,LAMTOR1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,NDST1,NEK10,PAK3,PDE6G,PDGFC,PDGFD,PIK3CB,PLCB1,PLCE1,PTPN22,PTPRC,RAF1,RAPGEF2,SERPINF2,TAB1,TNFAIP8L3,WNT5A |
| GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 0.0e+00 | 0.0e+00 | 1652 | 547 | 48 | ABCA7,ABL1,ACTN4,ANGPT1,ANXA13,AP2A1,APLN,APOC3,APOE,APPL2,AXL,AZU1,BACE1,C3,C4A,C4B,CADPS2,CALM3,CAV3,CD36,CNR1,DKK1,DLL1,DNM1,EHD2,F2RL1,FGR,GAS1,HFE,ITSN1,LRRK2,MAPK3,MYO18A,NLGN3,PIK3CB,PKDCC,PLD1,PRKD1,PTPRC,REST,RUFY1,SEPTIN8,SYT12,TBC1D5,VAMP8,VPS28,VPS41,WNT5A |
| GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1652 | 192 | 26 | APPL2,CAV3,CDKN1C,CDKN2B,COL1A2,COL3A1,DAND5,DKK3,EID2,ENG,FOLR1,FOXH1,GDF5,HPGD,MSTN,MTMR4,PBLD,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,TAB1,TGFBR3,TP53,ZBTB7A |
| GO_APPENDAGE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 179 | 25 | BMP4,DKK1,EN1,FMN1,FZD6,GDF5,HOXC13,IFT140,ITGB4,KAT2B,MEGF8,NOG,NR2F2,OSR1,PKDCC,RARG,RSPO2,SEMA3C,TBC1D32,TMEM107,TP63,WNT5A,ZBTB16,ZNF219,ZNF358 |
| GO_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1652 | 735 | 58 | AGT,ANXA8,ANXA8L1,APOE,ARL6IP5,BAD,BEX3,BOK,C3,C4A,C4B,CAAP1,CAPN3,CAV3,CCBE1,CLEC3B,CR1,CRIM1,CTSH,CTSZ,DET1,F2R,FBLN1,GAS1,GPER1,GPX1,HFE,ITIH3,LRRK2,MAP2K5,MAPK3,NEDD8,PANO1,PAPLN,PCOLCE,PCOLCE2,PRR7,RAF1,REST,RNF180,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SMAD3,SOCS5,SPINK9,SSPO,ST20,STAT3,STYX,TP53,TP63,VIL1,WFDC1,WFDC8,ZYG11B |
| GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1652 | 328 | 35 | AGT,ASCL1,ATP1A2,BAD,C9orf116,CAPN3,CNN2,COL1A1,CRIP1,DAG1,EFHD1,EIF2AK4,ENG,GATA3,GRM1,GTF2H5,HYAL1,MAPK3,MC1R,MME,MMP7,MYD88,MYLK,NSMF,OPN3,PDE6A,PDE6G,PIK3R1,PKD2,RCSD1,REST,RIPOR2,ST20,TNKS1BP1,TP53 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1652 | 853 | 64 | ADA,ADAMTS2,ADGRG2,ANGPT2,APOL2,AR,ARID4A,ATP1A4,AXL,B4GALT1,BAD,BMP4,C9orf24,CADM1,CCDC87,CNR1,CYP27B1,DDO,DEFB1,DKKL1,DNMT3A,H3-3A,HERC2,HPGD,KLHL10,LDOC1,LIMK2,LRRK2,MAPK3,MMP7,MSTN,NPHP1,NR2F2,PDE3A,PLEKHA1,PPARD,PYGO2,ROS1,RXRA,SERPINA5,SERPINF1,SIX5,SLC2A14,SLC2A8,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,SPIN1,SPIN2B,TDRD9,THRA,TMEM203,TOB2,TP63,TSNAXIP1,TSPAN8,TUT4,VCX,VDR,WASHC5,ZBTB16,ZNF541 |
| GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 282 | 32 | ACLY,ACSF3,ADA,ADCY6,AGPAT1,AGPAT4,AK1,AK3,CBR4,CTPS2,DGUOK,DMAC2L,ELOVL3,ELOVL5,FCSK,GPAM,HACD1,HACD2,KMO,NME3,NME4,NPR1,NUDT12,PANK1,PARP9,PDP2,SHMT1,SLC25A1,SLC26A1,SLC26A2,STAT3,TK2 |
| GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 0.0e+00 | 0.0e+00 | 1652 | 363 | 37 | AGBL4,ANKRD9,ANO8,APOE,APOL1,ASB13,ASB9,BMP4,C3,C4A,CISH,CUL9,DCAF8,FBXL15,FBXL19,FBXL22,FBXO41,FBXO9,FOLH1,FSTL1,IGFBP5,KBTBD6,KBTBD7,KLHL22,KLHL3,KLHL41,LAMB1,LAMB2,MSLN,MXRA8,NEDD8,NOTUM,OBSL1,RABGGTA,SOCS5,SUMF1,ZBTB16 |
| GO_TISSUE_MIGRATION | 0.0e+00 | 0.0e+00 | 1652 | 363 | 37 | ABL1,ACTA2,ACTG2,AGT,ANGPT1,ANGPT2,ANGPT4,APOE,ATOH8,BCAR1,BMP4,CCBE1,CTSH,DOCK1,DPP4,FAT2,FGF7,GATA3,GPX1,HYAL1,KANK2,MAP2K5,MCC,NANOS1,NR2F2,PBLD,PIK3R3,PLEKHG5,PPARD,PRKD1,SEMA4A,SERPINF1,SPARC,STARD13,TNFSF12,VIL1,WNT5A |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1652 | 518 | 46 | ABL1,AJUBA,APOE,BMP4,CALM3,CAV3,CCND3,CDKN1C,CDKN2B,DBNL,DKK1,DUSP19,ERBB2,ETAA1,F2R,FPR1,GRM1,HEXIM1,HEXIM2,IGF1R,KAT2B,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MTCP1,NEK10,NR2F2,PAK3,PDCD4,PDE6G,PDGFC,PDGFD,PIK3CB,PKD2,PLCE1,PRKCD,PTPN22,PTPRC,RAF1,RAPGEF2,STRADA,TAB1,WNT5A |
| GO_COENZYME_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1652 | 254 | 30 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,ALDH1L1,CBR4,COQ9,DBI,ELOVL3,ELOVL5,FOLH1,FOLR1,GPAM,HACD1,HACD2,KMO,MCCC1,NUDT12,NUDT13,PANK1,PARP9,PDP2,SHMT1,SLC25A1,SUCLG2,TPK1 |
| GO_REGULATION_OF_ENDOCYTOSIS | 0.0e+00 | 0.0e+00 | 1652 | 210 | 27 | ABCA7,ABL1,ACTN4,ANGPT1,AP2A1,APLN,APOC3,APOE,APPL2,AXL,C3,CALM3,CAV3,CD36,DKK1,DLL1,DNM1,F2RL1,HFE,ITSN1,LRRK2,PIK3CB,PRKD1,RUFY1,TBC1D5,VPS28,WNT5A |
| GO_ERK1_AND_ERK2_CASCADE | 0.0e+00 | 0.0e+00 | 1652 | 316 | 34 | ABCA7,ABL1,ACKR3,AGT,ANGPT1,APOE,BMP4,CALCR,CCR7,CD36,CD4,CTSH,ERBB2,F2R,F2RL1,FBLN1,GPER1,GPR183,HTR2C,MAP3K12,MAPK3,NEK10,PDGFC,PDGFD,PIN1,PKHD1,PSCA,PTPN22,PTPRC,RAPGEF2,ROS1,SERPINF2,STYX,TNFAIP8L3 |
| GO_NEPHRON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1652 | 143 | 22 | ACTA2,AGT,ANGPT1,ANGPT2,BMP4,DLL1,EYA1,FMN1,GATA3,IL6R,IRX3,KLF15,KLHL3,LAMB2,MYO1E,NOG,OSR1,PDGFD,PKD2,PLCE1,POU3F3,PTPRO |
| GO_CYTOSOLIC_CALCIUM_ION_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 183 | 25 | ABL1,ANK2,ATP1A2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CCR7,CD4,F2R,GPER1,GSTM2,HTR2C,JPH2,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,SELENON,TPCN2,TRPM2 |
| GO_REGULATION_OF_BLOOD_PRESSURE | 0.0e+00 | 1.0e-07 | 1652 | 183 | 25 | ACE2,ACTA2,AGT,APLN,AR,ATP1A2,CNR1,COL1A2,CPA3,CTSZ,DLL1,EDNRA,F2R,F2RL1,FFAR3,MME,NAV2,NPR1,NPR3,NR2F2,OR51E2,PTPRO,SERPINF2,SMAD3,TPM1 |
| GO_RESPONSE_TO_MECHANICAL_STIMULUS | 0.0e+00 | 1.0e-07 | 1652 | 211 | 27 | AGT,ANGPT2,ATP1A2,BACE1,BAD,BTG2,CACNB3,CAV3,CNN2,CNTNAP2,COL1A1,COL3A1,CXCL12,DAG1,ENG,GDF5,MAPK3,MMP7,MYD88,PKD2,PPL,RAF1,RIPOR2,SCN1A,SLITRK6,STRA6,TMC1 |
| GO_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 486 | 44 | ABL1,ACTN4,AGT,ANK2,ARL6IP5,ATP1A2,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CLCNKA,CLIC3,CTSS,F2R,FXYD3,GPER1,GSTM2,HECW2,JPH2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,NALCN,NLGN3,OSR1,PDZK1,PKD2,PSEN2,SCN1A,SCN2B,SELENON,STAC2,STIM1,STIMATE,TMC1,TPCN2,UTRN,WNK3 |
| GO_REGULATION_OF_METAL_ION_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 400 | 39 | ABL1,ACTN4,AGT,ANK2,ATP1A2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CD33,CD4,CXCL12,DMPK,EFHB,F2R,FXYD3,GPER1,GRAMD2A,GSTM2,HECW2,HFE,JPH2,KCNE3,KCNE4,KCNIP3,MYLK,OSR1,PKD2,PSEN2,SCN2B,SELENON,STAC2,STIM1,STIMATE,TMC1,UTRN,WNK3 |
| GO_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 1.0e-07 | 1652 | 65 | 15 | BMP4,BMP5,DKK1,ENG,GDF5,HFE,INHA,MSTN,NOG,PBLD,PIN1,PMEPA1,RBPMS,SNX25,TGFBR3 |
| GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 1.0e-07 | 1652 | 335 | 35 | AGT,ATP1A2,AXL,BAD,CACNB3,CADPS2,CDKN2B,CNN2,COL1A1,CYP27B1,DAG1,DNAJC15,EIF2AK4,ENG,FOLR1,GDAP1,HFE,KANK2,LRRK2,MAP1LC3C,MAPK3,MIOS,MMP7,MYD88,P2RY11,PRKD1,PTPRC,RIPOR2,RNF152,SESN1,TLE5,TP53,TXN2,USF2,VDR |
| GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1652 | 436 | 41 | ABCA7,ABCD1,ANK2,ANXA8,ANXA8L1,AR,ATP8B4,BLOC1S1,CASQ1,CAV3,CAVIN2,CHMP6,DMPK,DNM1,EHD2,F2R,GPER1,HOOK2,JAGN1,LAMTOR1,LRRK2,MAPK3,MOSPD3,MTSS2,MYO18A,MYOF,OBSL1,PLEKHF1,PLSCR1,PLSCR4,PRKCD,PRKD1,PTPRC,REEP3,SEC16A,SUN2,TRIP11,UBXN2B,VPS28,VPS33B,VPS37D |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 1.0e-07 | 1652 | 767 | 59 | ABL1,ALOX15B,ANGPT1,ANXA13,APOE,BAD,BMP4,CACNB3,CADM1,CCR7,CD33,CD36,CNR1,CRP,DPP4,EFNA5,EPHA5,ERBB2,F2R,F2RL1,FGR,GATA3,GIP,GPAM,GPER1,HADH,HMGN3,HSPA1L,IL17RC,IL27RA,JAGN1,KCNN4,LRRK2,MAPK3,MAVS,MMP12,MYO18A,MYOM1,OR51E2,ORM1,PDZK1,PIK3R1,PIK3R2,PKDCC,PPARD,PRKCD,PTPN22,RAB11FIP3,REST,SEC16A,SIDT2,SMAD3,SSC5D,TLR1,TP53,TP63,VPS28,WNT5A,ZIC1 |
| GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 1652 | 145 | 22 | ALDH3B1,ASAH1,B3GALT4,B4GALT6,CERS6,DPM3,ELOVL3,ELOVL5,HACD1,HACD2,MPPE1,PIGB,PIGQ,PIGS,PIGT,PRKCD,PRKD1,SGPP2,SPTSSA,ST3GAL6,ST6GALNAC5,ST6GALNAC6 |
| GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 0.0e+00 | 1.0e-07 | 1652 | 199 | 26 | ABL1,AGT,AR,BMP4,CAV3,CELSR1,CTSH,CTSZ,DAG1,DLG5,EDNRA,ENG,ESRP2,EYA1,FGF7,LRRK2,NOG,NTN4,PKD2,RSPO2,RXRA,SEMA3C,SEMA3E,TP63,VDR,WNT5A |
| GO_MYELOID_CELL_DIFFERENTIATION | 0.0e+00 | 1.0e-07 | 1652 | 420 | 40 | ACTN1,ADGRF5,ARID4A,BMP4,CCR7,CD4,CDKN1C,CDKN2B,DLL1,F2RL1,FAM210B,GATA3,GPR183,H3-3A,H3C6,HOXA7,INHA,INPP5D,JAGN1,KAT2B,MAFB,MB,MEIS1,MITF,MYL9,NFE2,P4HTM,PIAS3,PIK3R1,PRMT6,PRXL2A,RARG,RHAG,STAT3,TAL1,TGFBR3,THRA,TOB2,ZBTB16,ZBTB7A |
| GO_NEURON_DEATH | 0.0e+00 | 1.0e-07 | 1652 | 353 | 36 | ABL1,ADARB1,ANGPT1,APOE,ASCL1,AXL,BACE1,BAD,BHLHB9,BOK,BTG2,CTSZ,DKK1,EN1,F2R,GATA3,GDF5,ITSN1,KMO,LANCL1,LRRK2,MAP3K11,MAP3K12,NRBP2,NSMF,PAK3,PIGT,PIN1,REST,SERPINF1,STAR,STAT3,TP53,TP63,VSTM2L,WNT5A |
| GO_SENSORY_ORGAN_MORPHOGENESIS | 0.0e+00 | 1.0e-07 | 1652 | 258 | 30 | BMP4,CELSR1,COL5A2,COL8A2,DLL1,EFEMP1,EYA1,FZD6,GATA3,HOXC13,MAFB,MAPK3,MEIS1,NOG,OSR1,POU3F4,RARG,RIPOR2,ROM1,SLITRK6,STAT3,STOX1,STRA6,TRIOBP,TSHZ1,TSKU,TTC39C,VAX2,WNT5A,ZIC1 |
| GO_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1652 | 259 | 30 | ABL1,ACTR3B,ARPC5,ARPIN,CCR7,CFL1,CXCL12,DBNL,EPHA1,F2RL1,FHOD1,FHOD3,FMN1,GMFB,LIMA1,LMOD1,NAA80,PAK3,PIK3R1,PRKCD,SERPINF2,SMAD3,SPTBN2,SYNPO,TMOD1,TMSB15B,TPM1,TRIOBP,VIL1,VILL |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 1652 | 371 | 37 | ABL1,APCDD1,APOE,AXIN2,COL1A1,DKK1,DKK3,DKKL1,FOLR1,FZD6,GNAQ,INVS,JRK,LRRK2,MCC,NOG,NOTUM,PIN1,PPM1B,PTPRO,PTPRU,RBMS3,RNF213,RSPO2,SENP2,SMAD3,SPIN1,TAX1BP3,TBX18,TLE2,TLE5,TRABD2A,TRABD2B,TSKU,WNT5A,ZBED3,ZRANB1 |
| GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | 0.0e+00 | 1.0e-07 | 1652 | 260 | 30 | ACE2,ADA,AGT,ANK2,ATP1A2,CALM3,CASQ1,CAV3,CTNNA3,DAG1,DMPK,F2R,GPER1,GSTM2,GTF2IRD1,GTF2IRD2,IGFBP5,KCNE3,MLIP,MSTN,MTMR4,MYL9,PIN1,PLCE1,SELENON,SMAD3,TNNC1,TNNI2,TPM1,UTRN |
| GO_CALCIUM_ION_TRANSMEMBRANE_IMPORT_INTO_CYTOSOL | 0.0e+00 | 1.0e-07 | 1652 | 147 | 22 | ABL1,ANK2,ATP1A2,CALCR,CALM3,CAPN3,CASQ1,CCR7,F2R,GPER1,GSTM2,HTR2C,JPH2,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PTPRC,SELENON,TPCN2,TRPM2 |
| GO_LIPOSACCHARIDE_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1652 | 110 | 19 | AOAH,ARSA,ASAH1,B3GALT4,B4GALT6,CERK,DPM3,ITGB8,MPPE1,PIGB,PIGQ,PIGS,PIGT,PRKCD,ST3GAL6,ST6GALNAC5,ST6GALNAC6,STS,SUMF1 |
| GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS | 0.0e+00 | 1.0e-07 | 1652 | 231 | 28 | AGT,ANGPT2,APOL2,AR,B4GALT1,CNR1,CYP27B1,DDO,DKKL1,FBLN1,GIP,H3-3A,HFE,HPGD,IGFBP5,LDOC1,LNPEP,MAPK3,MMP2,MMP7,NR2F2,PPARD,PSG1,PSG3,RLN1,RXRA,STS,VDR |
| GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 277 | 31 | ABCA7,ABL1,ACE2,ACTN4,AGT,ANK2,APOE,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CD4,CTSS,CXCL12,F2R,GPER1,GSTM2,JPH2,KCNE3,KMO,MYLK,NLGN3,PDZK1,PKD2,PRKCD,STAC2,STIM1,STIMATE,VAMP8,WNK3 |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 1.0e-07 | 1652 | 569 | 48 | ABL1,ADGRG1,APOC3,APOE,ARHGEF17,ARHGEF25,CELSR1,CFL1,CHN1,COL1A2,COL3A1,DBNL,DOCK1,DOCK11,DOCK3,DOK1,F2R,F2RL1,FGD3,FGD4,IQSEC2,ITSN1,KANK2,LPAR6,LZTR1,MRAS,PDPN,PIK3R2,PLCE1,PLD1,PLEKHG5,PLEKHG6,PRKD1,RABL2A,RABL2B,RAC3,RAF1,RAPGEF2,RFXANK,RHOBTB2,RIN2,RIPOR2,RTKN,RUFY1,STARD13,TAX1BP3,TP53,TRIO |
| GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 204 | 26 | ABL1,ACTN4,AGT,ANK2,C3,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CTSS,F2R,GIP,GPER1,GSTM2,JPH2,KCNE3,KLF15,NLGN3,PDZK1,PIK3R1,PKD2,STAC2,STIM1,STIMATE,WNK3 |
| GO_FEMALE_PREGNANCY | 0.0e+00 | 1.0e-07 | 1652 | 191 | 25 | AGT,ANGPT2,APOL2,AR,CNR1,CYP27B1,FBLN1,GIP,H3-3A,HFE,HPGD,IGFBP5,LDOC1,LNPEP,MAPK3,MMP2,MMP7,NR2F2,PPARD,PSG1,PSG3,RLN1,RXRA,STS,VDR |
| GO_ORGANIC_ACID_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 328 | 34 | ABCC3,ABCD1,ACE2,AGT,APOE,ARL6IP5,ATP1A2,CD36,CPT2,EMB,FOLR1,KMO,NMB,OSR1,PDPN,PPARD,RXRA,SLC13A4,SLC16A14,SLC16A7,SLC1A1,SLC25A1,SLC26A1,SLC26A2,SLC27A2,SLC27A4,SLC35D1,SLC38A10,SLC7A7,SLCO1B1,SLCO2A1,STRA6,SV2A,TRPC4 |
| GO_STRIATED_MUSCLE_CONTRACTION | 0.0e+00 | 1.0e-07 | 1652 | 177 | 24 | ACE2,ANK2,ATP1A2,CALM3,CASQ1,CAV3,CCDC78,CTNNA3,DMPK,GSTM2,KCNE3,KCNE4,KCNJ3,KLHL41,MB,PPP1R13L,RCSD1,SCN1A,SCN2B,STAC2,TNNC1,TNNI2,TPM1,VEGFB |
| GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 125 | 20 | ABL1,ANK2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CD4,CXCL12,F2R,GPER1,GSTM2,JPH2,KCNE3,MYLK,PKD2,STAC2,STIM1,STIMATE,WNK3 |
| GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 1.0e-07 | 1652 | 346 | 35 | ABL1,ACTN4,AGT,ANK2,ATP1A2,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CTSS,F2R,FXYD3,GPER1,GSTM2,HECW2,JPH2,KCNE3,KCNE4,KCNIP3,NLGN3,OSR1,PDZK1,PKD2,PSEN2,SCN2B,SELENON,STAC2,STIM1,STIMATE,TMC1,UTRN,WNK3 |
| GO_CALCIUM_MEDIATED_SIGNALING | 0.0e+00 | 1.0e-07 | 1652 | 221 | 27 | ACKR3,ADA,ANK2,ATP1A2,AZU1,CALM3,CASQ1,CCR7,CD4,CXCR5,DEFB1,DMPK,EFHB,GSTM2,JPH2,LRRK2,P2RY11,PKD2,PLCE1,PTPRC,RCAN1,RCAN3,SELENON,STIMATE,TMBIM4,TPCN2,TRPM2 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 1.0e-07 | 1652 | 432 | 40 | ABL1,ACTR3B,AJUBA,APOE,ARPC5,ARPIN,CAV3,CCR7,CD36,CLDN7,DBNL,DKK1,DNAJC15,ERCC5,FHOD3,FMN1,FSCN1,GMFB,GTF2H5,H3-3A,INPP5J,JCHAIN,LMOD1,PAK3,PMEPA1,PRKCD,RAF1,SEPTIN8,SPTBN2,TAL1,THRA,TMOD1,TMSB15B,TP53,TRABD2A,TRABD2B,TRIOBP,VIL1,VILL,VPS41 |
| GO_REGULATION_OF_BLOOD_CIRCULATION | 0.0e+00 | 2.0e-07 | 1652 | 299 | 32 | ACE2,ADA,AGT,ANK2,APLN,ATP1A2,ATP1A4,CACNB3,CACNG8,CALM3,CASQ1,CAV3,CTNNA3,DMPK,F2R,F2RL1,FXYD3,GSTM2,HSPB7,KCNE3,KCNE4,KCNIP3,KCNJ3,KCNK15,NPR1,OR51E2,PTGER2,SCN2B,SLC1A1,STIM1,THRA,TPM1 |
| GO_CELLULAR_RESPONSE_TO_LIPID | 0.0e+00 | 2.0e-07 | 1652 | 615 | 50 | ABL1,ADCY6,AR,ATP1A2,AXL,BAD,BMP4,BRINP3,CD36,COL1A1,CYP27B1,CYP7B1,DAG1,EFNA5,FAM210B,FFAR3,FOXH1,GDAP1,GNAI1,GPAM,GPER1,KANK2,KMO,LDOC1,MAPK3,MSTN,MYD88,NR2F2,NR2F6,OR51E2,OSR1,PADI2,PDCD4,PLSCR4,PMEPA1,PPARD,PTGER2,PTPN22,RARG,REST,RORC,RXRA,SERPINF1,STAR,THRA,TP63,VDR,WNT5A,ZBTB7A,ZNF366 |
| GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 2.0e-07 | 1652 | 334 | 34 | ABL1,ANK2,ATP1A2,CACNB3,CACNG8,CALCR,CALM3,CAPN3,CASQ1,CAV3,CCR7,F2R,GPER1,GSTM2,HTR2C,JPH2,KCNE3,NALCN,PKD2,PLCB1,PLCD4,PLCE1,PLCH2,PSEN2,PTPRC,SELENON,SLC24A5,STAC2,STIM1,STIMATE,TMC1,TPCN2,TRPC4,TRPM2 |
| GO_LEUKOCYTE_MEDIATED_IMMUNITY | 0.0e+00 | 2.0e-07 | 1652 | 872 | 63 | ACLY,ACTR1B,AGL,ALDH3B1,ANPEP,ARPC5,ARSA,ASAH1,ATP8B4,AZU1,B4GALT1,BTN3A3,C1R,C1RL,C3,C4A,C4B,CADM1,CD33,CD36,CNN2,CPPED1,CR1,CRISP3,CRISPLD2,CRP,CTSH,CTSS,CTSZ,DBNL,F2RL1,FCGR2A,FGR,FPR1,GATA3,HFE,HGSNAT,HPSE,IGHV3-73,IL1R1,IL27RA,INPP5D,JAGN1,LAMTOR1,MAVS,METTL7A,MME,MMP25,NFAM1,OLR1,ORM1,PADI2,PARP3,PLAC8,PLD1,PRKCD,PTPRB,PTPRC,SERPINA3,SLC27A2,TMEM63A,TRPM2,VAMP8 |
| GO_PLATELET_ACTIVATION | 0.0e+00 | 2.0e-07 | 1652 | 154 | 22 | APOE,AXL,BLOC1S4,COL1A1,COL1A2,COL3A1,DGKA,DGKB,F2R,FZD6,GNA14,GNAQ,MAPK3,MYL9,PDPN,PIK3CB,PIK3R1,PLSCR1,PRKCD,RAF1,TLN1,VWF |
| GO_RESPONSE_TO_STEROID_HORMONE | 0.0e+00 | 2.0e-07 | 1652 | 385 | 37 | AGL,ALDH3A1,AR,ATP1A2,BAD,BMP4,CALCR,CALM3,COL1A1,CYP7B1,ENG,FOXH1,GPAM,GPER1,KANK2,MSTN,NR2F2,NR2F6,OR51E2,PADI2,PFKFB1,PMEPA1,PPARD,PTGER2,PTPRU,RARG,REST,RORC,RXRA,SERPINF1,SPARC,STAR,THRA,TP63,VDR,ZBTB7A,ZNF366 |
| GO_REGULATION_OF_PEPTIDASE_ACTIVITY | 0.0e+00 | 2.0e-07 | 1652 | 455 | 41 | AGT,ANXA8,ANXA8L1,ARL6IP5,BAD,BEX3,BOK,C3,C4A,C4B,CAAP1,CR1,CRIM1,CTSH,F2R,FBLN1,GPER1,GPX1,ITIH3,MAP2K5,MAPK3,PAPLN,PCOLCE,PCOLCE2,PRR7,RAF1,REST,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SMAD3,SPINK9,SSPO,ST20,STAT3,TP63,VIL1,WFDC1,WFDC8 |
| GO_LOCOMOTORY_BEHAVIOR | 0.0e+00 | 2.0e-07 | 1652 | 197 | 25 | ADGRL3,APOE,ATP1A2,CELSR1,CXCL12,DPP4,EN1,GIP,GMFB,GRM1,HTR2C,KLHL1,LRRK2,MEIS1,NAV2,PAK6,PEX13,SCN1A,SELENOP,SLITRK6,SPG11,TAL1,TMOD1,VPS13A,ZIC1 |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1652 | 547 | 46 | ADGRL3,AGT,AP2A1,APOE,ASCL1,BHLHB9,BMP4,BMP5,BRINP3,CDKL5,CNR1,CUX2,CXCL12,DAG1,DBNL,DKK1,DLG5,EFNA5,FAIM,FLRT3,GDF5,GPER1,IRX3,ITSN1,LRRC24,MEGF8,MME,NCKIPSD,NLGN3,NSMF,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,RAPGEF2,REST,SCARF1,SEMA4A,SERPINF1,SLITRK6,STAR,WASHC5,WNT5A |
| GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1652 | 439 | 40 | ADA,ADGRG1,ALOX15B,AR,ARID4A,AXL,BMP4,BMP5,BOK,CDKN1C,COL9A3,CRIP1,CYP27B1,CYP7B1,GATA3,H3-3A,INHA,ITGB8,KLHL10,LDOC1,LHX8,MAPK3,MME,NOG,NR2F2,OSR1,PKD2,PLEKHA1,PPARD,RARG,RXRA,SENP2,SERPINA5,SERPINF1,STAR,STRA6,TFEB,TP63,VDR,WNT5A |
| GO_ACTIN_FILAMENT_BASED_MOVEMENT | 0.0e+00 | 2.0e-07 | 1652 | 143 | 21 | ACTN4,ANK2,ATP1A2,CAV3,CTNNA3,FRMD6,KCNE3,KCNE4,KCNJ3,MYO1E,PDPN,SCN1A,SCN2B,SUN2,SYNE2,TMOD1,TNNC1,TNNI2,TPM1,TPM4,VIL1 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1652 | 337 | 34 | ACTN4,ADCY6,ADGRG1,APOE,APPL2,ASCL1,CAV3,COL3A1,CTSZ,DGUOK,DKK1,DLL1,EFNA5,EIF2AK4,FBLN1,INPP5J,IRX3,LRRK2,MEIS1,NLGN3,NOG,PTPRO,RAPGEF2,REST,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,STAT3,TP53,TRIM46,ULK2,WNT5A |
| GO_THIOESTER_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1652 | 105 | 18 | AASS,ABCD1,ACLY,ACOT1,ACOT11,ACOT2,ACSF2,ACSF3,CBR4,DBI,ELOVL3,ELOVL5,GPAM,HACD1,HACD2,PDP2,SLC25A1,SUCLG2 |
| GO_ACTIVATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 2.0e-07 | 1652 | 720 | 55 | ABL1,ADA,APPL2,ARPC5,BCAR1,BTN3A3,C1R,C1RL,C3,C4A,C4B,CACNB3,CCR7,CD36,CD4,CFB,CR1,CRP,CTLA4,CTSS,DOCK1,ERBIN,F2RL1,FCGR2A,FGR,FPR1,GATA3,GCSAM,HEXIM1,IGHV3-73,IKBKB,IKBKE,INPP5D,KCNN4,LAX1,MAPK3,MAVS,MUC15,MYD88,NCKIPSD,NFAM1,NLRX1,PAK3,PIK3CB,PIK3R1,PIK3R2,PLEKHA1,PLSCR1,PRKCD,PTPN22,PTPRC,PVRIG,RAF1,TAB1,TLR1 |
| GO_MUSCLE_ORGAN_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1652 | 407 | 38 | ADARB1,ANKRD2,BMP4,BTG2,CAPN3,CASQ1,CAV3,COL3A1,DKK1,DLL1,EID2,ENG,FOXH1,GPX1,IGSF8,ITGA11,JPH2,KLHL41,MEIS1,MRAS,MSTN,MYLK,MYOM1,MYOM3,NOG,NR2F2,PIN1,PRR14,RIPOR2,RXRA,SELENON,SMAD3,STRA6,TGFBR3,TNNC1,TPM1,UTRN,WNT5A |
| GO_POSITIVE_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 2.0e-07 | 1652 | 157 | 22 | ABL1,ACTN4,AGT,ANK2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CTSS,F2R,GPER1,GSTM2,JPH2,KCNE3,NLGN3,PDZK1,PKD2,STAC2,STIM1,STIMATE,WNK3 |
| GO_HEART_MORPHOGENESIS | 0.0e+00 | 3.0e-07 | 1652 | 259 | 29 | AXIN2,BMP4,BMP5,CAV3,CCDC40,CPE,DKK1,DLL1,ENG,EYA1,FOLR1,FOXH1,GATA3,MEGF8,MYOM1,MYOM3,NOG,PDCD4,PKD2,PPP1R13L,RXRA,SEMA3C,SMAD3,TAB1,TGFBR3,TNNC1,TP53,TPM1,WNT5A |
| GO_REGULATION_OF_VASCULATURE_DEVELOPMENT | 0.0e+00 | 3.0e-07 | 1652 | 425 | 39 | ABL1,ADAM12,AGGF1,AGT,ANGPT2,ANGPT4,BMP4,C3,CCBE1,CREB3L1,CTSH,DLL1,ENG,EPHA1,ERBB2,GPER1,GTF2I,HSPG2,HYAL1,IL6R,ITGB8,JMJD8,MAP2K5,NPR1,PDCD4,PDGFD,PRKD1,RAPGEF2,SEMA3E,SEMA4A,SERPINF1,SPARC,STARD13,STAT3,STIM1,TIE1,TNFSF12,VEGFB,WNT5A |
| GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | 0.0e+00 | 3.0e-07 | 1652 | 261 | 29 | ABL1,AGT,ANK2,ATP1A2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,CD33,CD4,CXCL12,EFHB,F2R,GPER1,GRAMD2A,GSTM2,JPH2,KCNE3,MYLK,PKD2,PSEN2,SELENON,STAC2,STIM1,STIMATE,TMC1,WNK3 |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1652 | 987 | 68 | ABCD1,ABL1,ANGEL2,APOC3,APOE,AREL1,ASB9,AXIN2,BAD,BOK,BTG2,CAV3,CHMP6,CNR1,CSDC2,DET1,EIF2AK4,ENTPD5,GPD1,GPX1,HECW2,HFE,JMJD8,KLHL22,LAMTOR1,LEPR,LGALS12,LRRK2,MAPK3,MYD88,NANOS1,NNT,NRBP2,PANO1,PCBP4,PFKFB1,PIK3CB,PIK3R2,PIN1,PIP4K2B,PLEKHF1,PLEKHG5,PPP1CB,PRKCD,PRKD1,PTPN22,RARRES2,RNF152,RNF180,SESN1,SMAD3,SOCS5,ST20,STAT3,STYX,TFEB,THRA,TNFSF12,TP53,TPCN2,TRIM22,ULK2,VPS13C,VPS28,WNT5A,ZBTB7A,ZC3H12D,ZYG11B |
| GO_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1652 | 74 | 15 | ALDH3B1,APOE,CEL,CYP27B1,IMPA2,INPP5A,INPP5J,LDHD,MAOA,NUDT3,SCARF1,SULT1A1,SULT1B1,SULT1E1,TRERF1 |
| GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 3.0e-07 | 1652 | 447 | 40 | ABL1,ADGRG1,APOC3,APOE,ARHGEF17,ARHGEF25,CELSR1,CFL1,COL1A2,COL3A1,DBNL,DOK1,F2R,F2RL1,FGD3,FGD4,IQSEC2,ITSN1,KANK2,LPAR6,LZTR1,MRAS,PDPN,PLCE1,PLD1,PLEKHG5,PLEKHG6,PRKD1,RABL2A,RABL2B,RAC3,RAF1,RAPGEF2,RFXANK,RHOBTB2,RIPOR2,RTKN,TAX1BP3,TP53,TRIO |
| GO_GLAND_MORPHOGENESIS | 0.0e+00 | 4.0e-07 | 1652 | 122 | 19 | AR,BMP4,CAV3,CRIP1,CYP7B1,DAG1,ESRP2,FGF7,IGFBP5,LIMS2,NFIB,NOG,NTN4,RARG,RXRA,SEMA3C,TP63,VDR,WNT5A |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 4.0e-07 | 1652 | 752 | 56 | ABL1,ACTR1B,ARMC4,BLOC1S1,BLOC1S4,BLOC1S5,CAV3,CCDC151,CCDC40,CCDC69,CCDC78,CEP70,CUL9,DAG1,DNAH10,DNAH3,EFNA5,EML3,ERBB2,FLOT2,GNAI1,HOOK2,ICK,IFT140,INPP5J,KAT2B,MAFIP,MAP3K11,MAP7D2,NAV1,NINL,OBSL1,PARP3,PEX13,PHLDB1,PKD2,PKHD1,PTPA,PURA,RABL2B,RASSF7,SPAG16,SPG11,STK36,SUN2,SYNE2,TRIM37,TRIM46,TRIP11,TTC30B,TUBA3D,TUBA3E,UBXN2B,WASHC5,WDR60,WDR66 |
| GO_MULTICELLULAR_ORGANISMAL_SIGNALING | 0.0e+00 | 4.0e-07 | 1652 | 204 | 25 | ACE2,AGT,ANK2,ATP1A2,ATP1A4,CACNB3,CACNG8,CALM3,CASQ1,CNTNAP1,CNTNAP2,CTNNA3,DMPK,FXYD3,GPER1,KCNE3,KCNE4,KCNIP3,KCNJ3,KCNK15,KCNMB3,NPR1,SCN1A,SCN2B,STIM1 |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 4.0e-07 | 1652 | 542 | 45 | ABL1,ACKR3,AJUBA,APOE,BMP4,CALM3,CAV3,CREB3L1,CXCL12,DAG1,DLG5,DUSP19,ERBIN,F2RL1,FBLN1,GPER1,GPX1,GSTM2,IGF1R,LAX1,LRRK2,LZTR1,MECOM,MGRN1,MSTN,NLRX1,PDCD4,PDE3A,PHLPP1,PIK3R2,PIN1,PKD2,PKHD1,PLEKHA1,PPM1B,PRKCD,PSCA,PTPN22,PTPRC,RCAN1,RIPOR2,RNF152,SESN1,SPAAR,TRIM59 |
| GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | 0.0e+00 | 4.0e-07 | 1652 | 205 | 25 | ACTR3B,ARPC5,ARPIN,CCR7,CFL1,CORO7,CXCL12,DBNL,F2RL1,FHOD3,FMN1,GMFB,LIMA1,LMOD1,MSRB1,MSRB2,NAA80,PAK3,PRKCD,SPTBN2,TMOD1,TMSB15B,TRIOBP,VIL1,VILL |
| GO_APPENDAGE_MORPHOGENESIS | 0.0e+00 | 5.0e-07 | 1652 | 149 | 21 | BMP4,DKK1,EN1,FMN1,FZD6,GDF5,IFT140,MEGF8,NOG,OSR1,PKDCC,RARG,RSPO2,SEMA3C,TBC1D32,TMEM107,TP63,WNT5A,ZBTB16,ZNF219,ZNF358 |
| GO_MUSCLE_CELL_DIFFERENTIATION | 0.0e+00 | 5.0e-07 | 1652 | 383 | 36 | ABL1,ADAM12,AGT,ALPK3,ANK2,ANKRD2,BMP4,CAPN3,CASQ1,CAV3,DKK1,DLL1,DMPK,EHD2,ENG,FHOD3,GPER1,GPX1,H3-3A,IGFBP5,KLHL41,LDB3,LMOD1,MYOF,MYOM1,MYOM3,NEBL,OBSL1,PDCD4,PIN1,PLPP7,RIPOR2,RXRA,SELENON,TMOD1,TPM1 |
| GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 5.0e-07 | 1652 | 99 | 17 | AGPAT1,AGPAT4,AK3,APOBEC3C,APOBEC3G,CTPS2,DPYD,DPYS,ENTPD4,GPAM,NEIL1,NME3,NME4,SHMT1,TK2,TKTL1,TPK1 |
| GO_XENOBIOTIC_METABOLIC_PROCESS | 0.0e+00 | 5.0e-07 | 1652 | 124 | 19 | ALDH3A1,AOC2,AOC3,CYP2C18,CYP2E1,FMO1,FMO2,FMO3,GSTA1,GSTA2,GSTM2,MARC2,MGST2,RORC,STAR,SULT1A1,SULT1B1,UGT1A6,UGT2B11 |
| GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 6.0e-07 | 1652 | 351 | 34 | ABL1,ACTR3B,APOE,ARPC5,ARPIN,CAV3,CCR7,CFL1,CXCL12,DBNL,EPHA1,F2RL1,FHOD1,FHOD3,FMN1,GMFB,GPX1,INPP5J,LIMA1,LMOD1,NAA80,PAK3,PIK3R1,PRKCD,SERPINF2,SMAD3,SPTBN2,SYNPO,TMOD1,TMSB15B,TPM1,TRIOBP,VIL1,VILL |
| GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 6.0e-07 | 1652 | 270 | 29 | ACLY,APOE,ASAH1,BMP5,CYP27B1,CYP7B1,DKK3,DKKL1,GATA3,GPAM,GPER1,HSD3B7,IMPA2,IP6K3,ISYNA1,MC1R,OSBPL9,PLCB1,PLCD4,PLCE1,PLCH2,RAPGEF2,REST,SCP2,SLC24A5,SLC27A2,STAR,VDR,WNT5A |
| GO_POLYOL_METABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 1652 | 125 | 19 | ASAH1,CYP27B1,GPER1,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,MYOF,NUDT3,PLCB1,PLCD4,PLCE1,PLCH2,PLD4,SGPP2,SLC5A3 |
| GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION | 0.0e+00 | 6.0e-07 | 1652 | 194 | 24 | ABL1,CAPN3,CASQ1,CAV3,CDC42BPB,CNN2,EPHA1,FHOD1,FHOD3,FRMD6,KLHL41,LDB3,LMOD1,MYO18A,MYOM1,MYOM3,NEBL,OBSL1,PIK3R1,RTKN,SERPINF2,SMAD3,TMOD1,TPM1 |
| GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL | 0.0e+00 | 6.0e-07 | 1652 | 209 | 25 | ADCY6,BRINP3,COL1A1,COL1A2,COL3A1,COL5A2,DNMT3A,FFAR3,FOLR1,KLHL22,LAMTOR1,MMP2,NSMF,OR51E2,OSR1,PDGFC,PDGFD,PKD2,PTGER2,RARG,SERPINF1,SESN1,SHMT1,SPAAR,WNT5A |
| GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 0.0e+00 | 7.0e-07 | 1652 | 39 | 11 | ANK2,CACNB3,CALM3,CASQ1,GSTM2,JPH2,KCNE3,PKD2,STAC2,STIM1,STIMATE |
| GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | 0.0e+00 | 8.0e-07 | 1652 | 114 | 18 | ANGPT1,AP2A1,B3GNT10,B4GALT1,B4GALT6,BGN,CHST14,CHST9,EXT2,GALNT5,HS3ST3B1,HSPG2,HYAL1,NDST1,NDST4,SLC35D1,ST3GAL3,ST3GAL6 |
| GO_PHOSPHOLIPID_TRANSPORT | 0.0e+00 | 8.0e-07 | 1652 | 90 | 16 | ABCA12,ABCA4,ABCA7,APOC3,APOE,ATP8B4,CETP,KCNN4,MTTP,OSBPL5,PITPNM2,PLSCR1,PLSCR4,PRKCD,SCP2,TNFAIP8L3 |
| GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 0.0e+00 | 8.0e-07 | 1652 | 273 | 29 | ABL1,AJUBA,ANGPT1,APOL3,CAPN3,CCR7,CD36,CD4,CXXC5,F2R,F2RL1,FAIM,IKBKB,IKBKE,IRAK1BP1,JMJD8,MAVS,MYD88,NLRX1,PLEKHG5,PPM1B,PRKD1,SECTM1,TAB1,TIAF1,TMEM9B,TRIM22,TRIM59,WNT5A |
| GO_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 0.0e+00 | 8.0e-07 | 1652 | 444 | 39 | ABL1,AGT,APOE,ATP1A2,BACE1,CACNB3,CALM3,CEL,CNR1,CNTNAP4,CUX2,DGKB,DKK1,DMPK,DNM1,EIF2AK4,EIF4EBP2,F2R,GIP,GNAI1,GPER1,GRM1,IQSEC2,KMO,LRRK2,MME,NLGN3,NSMF,PLCB1,PLEKHG5,PNKD,PTPRA,RAPGEF2,SNCAIP,STAR,STAT3,SYNPO,SYT12,UNC13C |
| GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 8.0e-07 | 1652 | 274 | 29 | ADGRL3,AJUBA,CADM1,CADM3,CDH6,CELSR1,CELSR3,CLDN7,EFNA5,EMB,FAT2,FLRT3,MAP2K5,PCDH15,PCDH9,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PCDHB8,PCDHGA2,PCDHGB6,PCDHGC3,PIK3CB,PLXNB2,PLXNB3,SCARF2,TENM2,VSTM2L |
| GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 8.0e-07 | 1652 | 463 | 40 | ABL1,AGT,ANXA8,ANXA8L1,APOC3,BEX3,C3,C4A,C4B,CAAP1,CABIN1,CR1,CRIM1,GCHFR,GPX1,IKBKB,ITIH3,LEPR,LRRK2,MAP2K5,NEIL1,PAPLN,PCIF1,PLXNB3,PPP1R35,PTPA,RAF1,RTKN,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SPINK9,SSPO,TP53,VIL1,WDR81,WFDC1,WFDC8 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 9.0e-07 | 1652 | 537 | 44 | ABCA12,ABCA7,ANGPT1,ANXA13,AR,BAD,BMP4,CACNB3,CAV3,CD36,DAG1,ERBB2,GNAI1,GPER1,GPM6B,HFE,HSPA1L,IQSEC2,LRRK2,LYPD1,MAVS,PARP9,PDZK1,PIK3R1,PIK3R2,PIN1,PKDCC,PRKCD,RIPOR2,SEC16A,SMAD3,STAC2,TAX1BP3,TP53,TP63,TRIM29,TRIM46,UBXN2B,VAMP8,VIL1,VPS28,WNK3,WNT5A,ZIC1 |
| GO_MUSCLE_CELL_DEVELOPMENT | 0.0e+00 | 9.0e-07 | 1652 | 183 | 23 | AGT,ALPK3,ANK2,BMP4,CAPN3,CASQ1,CAV3,ENG,FHOD3,GPX1,KLHL41,LDB3,LMOD1,MYOF,MYOM1,MYOM3,NEBL,OBSL1,PIN1,RIPOR2,SELENON,TMOD1,TPM1 |
| GO_NEURON_APOPTOTIC_PROCESS | 0.0e+00 | 9.0e-07 | 1652 | 243 | 27 | ADARB1,ANGPT1,APOE,ASCL1,AXL,BACE1,BHLHB9,BOK,BTG2,CTSZ,EN1,F2R,GATA3,GDF5,ITSN1,LANCL1,MAP3K11,MAP3K12,NRBP2,NSMF,PAK3,PIGT,PIN1,STAR,TP53,TP63,VSTM2L |
| GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 0.0e+00 | 9.0e-07 | 1652 | 291 | 30 | ADAM12,AGT,ALPK3,ANKRD2,BMP4,CAPN3,CASQ1,CAV3,DKK1,DLL1,DMPK,EHD2,FHOD3,GPX1,IGFBP5,KLHL41,LDB3,LMOD1,MYOF,MYOM1,MYOM3,NEBL,OBSL1,PIN1,PLPP7,RIPOR2,RXRA,SELENON,TMOD1,TPM1 |
| GO_AMINOGLYCAN_METABOLIC_PROCESS | 0.0e+00 | 9.0e-07 | 1652 | 169 | 22 | ANGPT1,AP2A1,B3GNT10,B4GALT1,B4GALT6,BGN,CHST14,CHST9,EXT2,GALNT5,HGSNAT,HPSE,HS3ST3B1,HSPG2,HYAL1,ITIH3,NDST1,NDST4,SGSH,SLC35D1,ST3GAL3,ST3GAL6 |
| GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS | 1.0e-07 | 9.0e-07 | 1652 | 244 | 27 | ABL1,ADA,ADGRF5,ARID4A,AXL,BMP4,CCR7,DOCK11,F2R,FAM210B,GATA3,GPAM,GPR183,INHA,INPP5D,KLHL10,MAFB,MB,P4HTM,PIK3CB,RAC3,RHAG,STAT3,TAL1,TGFBR3,THRA,ZBTB7A |
| GO_RESPONSE_TO_TOXIC_SUBSTANCE | 1.0e-07 | 9.0e-07 | 1652 | 539 | 44 | ABL1,ADA,APOE,ATP1A2,AXL,BAD,CALM3,CD36,CLDN7,CNR1,COL1A1,CPOX,CYGB,CYP2E1,DNMT3A,GATA3,GNAT3,GPX1,GPX8,GSTA1,GSTM2,HPGD,LRRK2,LYPD1,MAPK3,MARC2,MB,MGST2,MSTN,NNT,PDGFD,PDZK1,PLEKHA1,PRKCD,PRXL2A,RDH11,SCN2B,SESN1,SLC15A2,SPARC,STAR,STAT3,TP53,TRPM2 |
| GO_CELL_JUNCTION_ORGANIZATION | 1.0e-07 | 1.0e-06 | 1652 | 293 | 30 | ABL1,ACE2,ACTN1,ACTN4,AGT,AJUBA,ANK2,CADM1,CADM3,CDH6,CNTNAP1,DLG5,EFNA5,F2R,F2RL1,FMN1,FSCN1,GPM6B,IKBKB,ITGB4,KRT14,KRT5,LAMA3,LIMS2,NPHP1,PLEKHA7,PTPRO,RAPGEF2,SMAD3,TLN1 |
| GO_LYMPHOCYTE_ACTIVATION | 1.0e-07 | 1.1e-06 | 1652 | 736 | 54 | ABL1,ADA,AXL,BAD,BMP4,CCND3,CCR7,CD4,CD7,CR1,CTLA4,CXCR5,DLG5,DLL1,DOCK11,DPP4,EIF2AK4,ERBB2,F2RL1,FGR,FLOT2,GATA3,GPAM,GPR183,HFE,HSH2D,IGHV3-73,IL27RA,INHA,INPP5D,LAX1,LEPR,LOXL3,LY6D,MAFB,NFAM1,PAK3,PARP3,PIK3R1,PRKCD,PRR7,PTPN22,PTPRC,PURA,RIPOR2,RORC,SEMA4A,SMAD3,SOCS5,STAT3,TP53,ZBTB16,ZBTB7A,ZBTB7B |
| GO_REGULATION_OF_CARTILAGE_DEVELOPMENT | 1.0e-07 | 1.1e-06 | 1652 | 70 | 14 | ADAMTS7,AXIN2,BMP1,BMP4,EFEMP1,GDF5,NOG,PKDCC,RARG,SMAD3,SOX5,WNT5A,ZBTB16,ZNF219 |
| GO_LIPOPROTEIN_METABOLIC_PROCESS | 1.0e-07 | 1.1e-06 | 1652 | 130 | 19 | APOC3,APOE,APOL1,APOL2,APOL3,APOL4,DPM3,LYPLA2,MPPE1,MTTP,NOTUM,PIGB,PIGQ,PIGS,PIGT,PPM1B,ZDHHC12,ZDHHC16,ZDHHC21 |
| GO_REGULATION_OF_CELL_ACTIVATION | 1.0e-07 | 1.1e-06 | 1652 | 619 | 48 | ABL1,ADA,ADGRF5,APOE,AXL,BAD,BMP4,CAPN3,CCR7,CD4,CNR1,CR1,CTLA4,CYGB,DLG5,DPP4,ERBB2,F2RL1,FGR,FLOT2,GATA3,GPAM,GPER1,GPR183,HFE,IGHV3-73,IL27RA,INHA,INPP5D,LAX1,LOXL3,LRRK2,MYO18A,NFAM1,PAK3,PARP3,PDPN,PIK3R1,PLSCR1,PRKCD,PTPN22,PTPRC,RIPOR2,SOCS5,VAMP8,WNT5A,ZBTB16,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_GROWTH | 1.0e-07 | 1.2e-06 | 1652 | 247 | 27 | AGT,ALOX15B,APBB2,BMP4,CAV3,CYP27B1,HYAL1,IGFBP5,MEIS1,MSTN,NOG,NPR1,PLAC8,PPARD,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SMARCA2,ST20,TP53,TRIM46,TSPYL2,ULK2,WFDC1,WNT5A |
| GO_CARDIAC_CHAMBER_DEVELOPMENT | 1.0e-07 | 1.2e-06 | 1652 | 172 | 22 | ANK2,BMP4,BMP5,CAV3,CPE,DAND5,ENG,FOXH1,GATA3,NDST1,NOG,PPP1R13L,RXRA,SEMA3C,STRA6,TAB1,TGFBR3,TNNC1,TP53,TPM1,TRIP11,WNT5A |
| GO_NERVOUS_SYSTEM_PROCESS | 1.0e-07 | 1.2e-06 | 1652 | 1441 | 87 | ABCA4,ABCA7,ABCC6,ABL1,ACE2,ADARB1,AFF2,AGT,AOC2,APOE,ATP1A2,ATP6V0A4,BACE1,BEST2,BHLHB9,BLOC1S4,BTG2,CACNB3,CACNG8,CD36,CNGB3,CNR1,CNTNAP1,CNTNAP2,COL18A1,COL1A1,CUX2,CXCL12,DAG1,DKK1,DMPK,EFEMP1,EIF2AK4,EIF4EBP2,EN1,EYA1,F2R,GIP,GMFB,GNAT3,GPER1,GPX1,GRM1,HTR2C,KCNMB3,LAMB2,LHX8,LRRK2,MAPK3,MC1R,METTL23,MME,NAV2,NIPSNAP1,NLGN3,NR2F6,OPA3,OR1F2P,OR2T8,OR51E2,OR5A2,PAK6,PCDH15,PDE6A,PDE6G,PLCB1,PNKD,POU3F4,POU6F2,RABGGTA,RAC3,RIPOR2,ROM1,RTP4,SCN1A,SCNN1B,SERPINF1,SHROOM4,SLITRK6,STRA6,SYNPO,TAS2R10,TGFBI,THRA,TMC1,TRIOBP,VAX2 |
| GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 1.0e-07 | 1.2e-06 | 1652 | 158 | 21 | ABL1,ANK2,ATP1A2,CACNB3,CALCR,CALM3,CAPN3,CASQ1,CAV3,F2R,GPER1,GSTM2,JPH2,KCNE3,PKD2,PSEN2,SELENON,STAC2,STIM1,STIMATE,TMC1 |
| GO_INOSITOL_PHOSPHATE_METABOLIC_PROCESS | 1.0e-07 | 1.3e-06 | 1652 | 71 | 14 | GPER1,IMPA2,INPP5A,INPP5D,INPP5J,INPPL1,IP6K3,ISYNA1,NUDT3,PLCB1,PLCD4,PLCE1,PLCH2,PLD4 |
| GO_TEMPERATURE_HOMEOSTASIS | 1.0e-07 | 1.3e-06 | 1652 | 173 | 22 | ACADL,ACOT11,APLN,APPL2,CD36,CNR1,CPT2,ELOVL3,GPX1,HADH,IGF1R,LEPR,LNPEP,NPR3,OMA1,PDGFC,PLAC8,STAT3,THRA,TRPM2,UCP2,ZBTB7B |
| GO_REGULATION_OF_CELL_CYCLE | 1.0e-07 | 1.4e-06 | 1652 | 1224 | 77 | ABL1,ADARB1,ALOX15B,ANAPC11,ANAPC16,ANGEL2,APBB2,ASCL1,AXIN2,BMP4,BRINP3,BTG2,CABLES1,CALM3,CCND3,CDK15,CDKL5,CDKN1C,CDKN2B,CEP70,CNOT11,CUL9,CXCR5,DACH1,EIF2AK4,ETAA1,FBXL22,GAS1,GATA3,GNAI1,GPER1,HECW2,HEXIM1,HEXIM2,HPGD,HYAL1,INHA,INTS3,KANK2,KAT2B,KLHL22,LAMTOR1,MDC1,MECOM,NACC2,NEK10,NINL,NR2F2,OBSL1,PARP3,PCBP4,PDCD4,PDE3A,PIN1,PKD2,PKHD1,PLCB1,PTPRC,RAB11FIP3,RBL2,SENP2,SMAD3,SPIN2B,STAT3,STOX1,STRADA,TAL1,TGM1,TNKS1BP1,TOM1L2,TP53,TRIM37,TSPYL2,TTC28,UBXN2B,USP22,WNT5A |
| GO_REGULATION_OF_DEVELOPMENTAL_GROWTH | 1.0e-07 | 1.4e-06 | 1652 | 348 | 33 | ABL1,APOE,AR,ATRN,BMP4,CAPN3,CAV3,CDKL5,CXCL12,DBNL,DLL1,EFNA5,GDF5,GPAM,MEGF8,MEIS1,MSTN,NOG,PIN1,PLAC8,PLCB1,PPARD,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPAAR,STAT3,TGFBR3,TRIM46,ULK2,VIL1,WNT5A |
| GO_CARDIAC_CONDUCTION | 1.0e-07 | 1.5e-06 | 1652 | 146 | 20 | ACE2,AGT,ANK2,ATP1A2,ATP1A4,CACNB3,CACNG8,CALM3,CASQ1,CTNNA3,DMPK,FXYD3,KCNE3,KCNE4,KCNIP3,KCNJ3,KCNK15,NPR1,SCN2B,STIM1 |
| GO_CARBOHYDRATE_DERIVATIVE_CATABOLIC_PROCESS | 1.0e-07 | 1.5e-06 | 1652 | 189 | 23 | ABCD1,ADA,AOAH,APOBEC3C,APOBEC3G,BGN,DPYD,DPYS,EDEM3,ENTPD4,GPD1,HGSNAT,HPSE,HSPG2,HYAL1,MMP12,NEIL1,NUDT3,PDE1A,PDE7B,PDE8B,PRKCD,SGSH |
| GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN | 1.0e-07 | 1.5e-06 | 1652 | 26 | 9 | ACE2,AGT,CPA3,CTSZ,F2R,F2RL1,MME,OR51E2,SERPINF2 |
| GO_ORGANOPHOSPHATE_ESTER_TRANSPORT | 1.0e-07 | 1.6e-06 | 1652 | 120 | 18 | ABCA12,ABCA4,ABCA7,ABCD1,APOC3,APOE,ATP8B4,CETP,KCNN4,MTTP,OSBPL5,PITPNM2,PLSCR1,PLSCR4,PRKCD,SCP2,SLC37A2,TNFAIP8L3 |
| GO_EAR_DEVELOPMENT | 1.0e-07 | 1.7e-06 | 1652 | 220 | 25 | BMP4,BMP5,CELSR1,DLL1,EYA1,FZD6,GATA3,MAFB,MAPK3,NOG,OSR1,PCDH15,POU3F4,RIPOR2,SLITRK6,SPARC,STOX1,STRA6,TMC1,TRIOBP,TRIP11,TSHZ1,TTC39C,WNT5A,ZIC1 |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 1.0e-07 | 1.7e-06 | 1652 | 767 | 55 | AGFG2,AGT,ARL6IP5,BAD,BEX3,BOK,CALM3,CCR7,CD33,CDKL5,CHN1,CR1,CTSH,DNAJC15,DOCK1,DOCK11,EDNRA,EPHA1,ERBB2,F2R,F2RL1,FBLN1,GNAQ,GPER1,LPAR2,LRRK2,MAPK3,MTSS2,PCOLCE,PCOLCE2,PIN1,PLCB1,PLEKHG6,PLSCR1,PLXNB1,PRKCD,PRKD1,PRR7,PTPA,PTPRC,RANBP3L,RAPGEF2,REST,RIN2,SMAD3,ST20,STARD13,STAT3,TAX1BP3,TBC1D2B,TBC1D5,TBC1D9,TPM1,WDR60,WNT5A |
| GO_SENSORY_SYSTEM_DEVELOPMENT | 1.0e-07 | 1.7e-06 | 1652 | 369 | 34 | BMP4,C3,CDKN1C,COL5A2,COL8A2,DLL1,EFEMP1,FKBP8,GATA3,IFT140,LAMB2,LIMK2,MEIS1,MITF,MYOM1,NPHP1,PDE6A,PPP1R13L,PYGO2,RARG,ROM1,RXRA,SERPINF1,SIX5,SLITRK6,SMAD3,STAT3,STRA6,TBC1D32,TMOD1,TSKU,VAX2,WNT5A,ZDHHC16 |
| GO_LUNG_MORPHOGENESIS | 1.0e-07 | 1.7e-06 | 1652 | 52 | 12 | BMP4,CELSR1,CTSH,CTSZ,DAG1,DLG5,ESRP2,FGF7,MAPK3,NFIB,NOG,RSPO2 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 1.0e-07 | 1.8e-06 | 1652 | 1410 | 85 | ADAMTS7,AGL,ANAPC11,ANAPC16,ANGEL2,AOAH,AP2A1,APOE,AREL1,ASB9,AXIN2,BACE1,BGN,BTG2,CAPN3,CAV3,CHMP6,CNOT11,CSDC2,CTSH,CTSO,CTSS,CTSZ,CUL9,DET1,EDEM3,FBXL15,FBXL17,FBXL19,FBXL22,FBXO9,GPX1,HECW2,HERC2,HFE,HGSNAT,HPSE,HSPG2,HYAL1,KLHL22,KLHL3,LNPEP,LRRK2,LYPLA2,MMP12,MYD88,NANOS1,NEDD8,NOTUM,NUDT12,OMA1,PAN2,PANO1,PCBP4,PIN1,PLEKHG5,PPP1CB,PRKCD,PYGM,PYM1,RNF150,RNF180,RNF213,SGSH,SIDT2,SMAD3,SNX25,SOCS5,ST20,STYX,TMEM129,TNFSF12,TNKS1BP1,TUT4,UBA7,UBE3B,UBXN2B,USP22,VPS28,VPS37D,WDR81,WNT5A,ZC3H12D,ZRANB1,ZYG11B |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1.0e-07 | 1.8e-06 | 1652 | 459 | 39 | ABL1,ALOX15B,ANXA13,BAD,CACNB3,CADM1,CD33,ERBB2,F2R,F2RL1,FGR,GATA3,GIP,GPER1,HSPA1L,IL17RC,KCNN4,LRRK2,MAPK3,MAVS,MMP12,MYO18A,MYOM1,OR51E2,ORM1,PDZK1,PIK3R1,PIK3R2,PPARD,PRKCD,PTPN22,SEC16A,SMAD3,TLR1,TP53,TP63,VPS28,WNT5A,ZIC1 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | 1.0e-07 | 1.8e-06 | 1652 | 121 | 18 | CAV3,CDKN1C,CDKN2B,DAND5,DKK3,EID2,ENG,FOLR1,MTMR4,PBLD,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,TGFBR3,TP53,ZBTB7A |
| GO_SODIUM_ION_TRANSPORT | 1.0e-07 | 1.8e-06 | 1652 | 221 | 25 | ACTN4,ATP1A2,ATP1A4,CAV3,DMPK,FXYD3,HECW2,KLHL3,NALCN,OSR1,PKD2,SCN1A,SCN2B,SCNN1B,SLC13A4,SLC20A2,SLC22A5,SLC24A5,SLC38A10,SLC5A2,SLC5A3,SLC9A9,TRPM2,UTRN,WNK3 |
| GO_LYMPHOCYTE_DIFFERENTIATION | 1.0e-07 | 2.0e-06 | 1652 | 354 | 33 | ABL1,ADA,AXL,BAD,BMP4,CCR7,CD4,CR1,CTLA4,DLL1,DOCK11,ERBB2,GATA3,GPR183,INHA,INPP5D,LEPR,LOXL3,LY6D,MAFB,NFAM1,PIK3R1,PRR7,PTPN22,PTPRC,RORC,SEMA4A,SOCS5,STAT3,TP53,ZBTB16,ZBTB7A,ZBTB7B |
| GO_RESPONSE_TO_BACTERIUM | 1.0e-07 | 2.0e-06 | 1652 | 711 | 52 | ABL1,AXL,AZU1,C3,C4B,CCDC80,CCR7,CD36,CD4,CNR1,CRP,CYP27B1,CYP2E1,DEFB1,DGKB,ERBIN,F2R,F2RL1,FGR,FKBP5,FMO1,GPX1,HPGD,IGHV3-73,IL27RA,IL6R,JCHAIN,KMO,LDOC1,LYPD8,MAPK3,MAVS,MGST2,MR1,MYD88,NFIB,PDCD4,PLAC8,PLSCR4,PPARD,PRKCD,PTGER2,PTPN22,RARRES2,SPARC,SSC5D,STAR,TLR1,TMEM229B,VDR,VIL1,WNT5A |
| GO_GLOMERULUS_DEVELOPMENT | 1.0e-07 | 2.1e-06 | 1652 | 63 | 13 | ACTA2,ANGPT1,ANGPT2,BMP4,IL6R,KLF15,LAMB2,MYO1E,NOG,OSR1,PDGFD,PLCE1,PTPRO |
| GO_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | 1.0e-07 | 2.0e-06 | 1652 | 254 | 27 | ABCA12,ABCA7,ABCC3,AGT,APOC3,APOE,AQP7,CD36,CEL,CETP,CNR1,CXCL12,EMB,FFAR3,GPM6B,LAMTOR1,LIMA1,OSBPL5,RXRA,SCP2,SLC16A7,SLC5A3,SLCO1B1,STAR,STRA6,SYT12,TTC39B |
| GO_PEPTIDYL_TYROSINE_MODIFICATION | 1.0e-07 | 2.1e-06 | 1652 | 372 | 34 | ABL1,AGT,ANGPT1,ANGPT4,AXL,CD36,CD4,CHMP6,DOCK3,EFEMP1,EFNA5,EPHA1,EPHA5,ERBB2,FGF7,FGR,IGF1R,IL27RA,IL6R,MAP2K5,MAPK3,PARP9,PDGFC,PDGFD,PKDCC,PRKCD,PTPRC,ROS1,SOCS5,STAT3,STK16,TAL1,TIE1,TP53 |
| GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 1.0e-07 | 2.1e-06 | 1652 | 390 | 35 | AGT,AP2A1,APOE,BHLHB9,BMP5,CCR7,CDKL5,CNR1,CUX2,CXCL12,DBNL,DLG5,DOCK11,EFNA5,F2RL1,FSCN1,ITSN1,MEGF8,MSTN,NCKIPSD,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,RAPGEF2,RIPOR2,SCARF1,SERPINF1,TENM2,VIL1,WASHC5,WNT5A |
| GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 1.0e-07 | 2.0e-06 | 1652 | 337 | 32 | AJUBA,BMP4,CALM3,CCND3,DBNL,DKK1,DUSP19,ERBB2,ETAA1,F2R,FPR1,GRM1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,MTCP1,NEK10,PAK3,PDE6G,PDGFC,PDGFD,PIK3CB,PKD2,PLCE1,PTPRC,RAF1,RAPGEF2,STRADA,TAB1,WNT5A |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 1.0e-07 | 2.1e-06 | 1652 | 499 | 41 | ABL1,BAD,BOK,CHMP6,EIF2AK4,FUNDC1,ITGB4,KLHL22,KLHL3,LAMTOR1,LEPR,LRRK2,MAP1LC3C,MAPK3,NRBP2,PIK3CB,PIK3R2,PIP4K2B,PLEKHF1,PRKD1,PTPN22,RNF152,SESN1,STAT3,TBC1D5,TECPR1,TEX264,TFEB,TP53,TPCN2,TRIM22,UBXN2B,ULK2,VAMP8,VPS13A,VPS13C,VPS28,VPS37D,VPS39,VPS41,WDR81 |
| GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 1.0e-07 | 2.1e-06 | 1652 | 338 | 32 | AJUBA,APOE,BMP4,CAV3,DBNL,DKK1,DUSP19,ERBB2,F2R,FPR1,GRM1,IGF1R,LAX1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,NEK10,PAK3,PDCD4,PDE6G,PDGFC,PDGFD,PIK3CB,PLCE1,PRKCD,PTPN22,PTPRC,RAF1,TAB1,WNT5A |
| GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | 1.0e-07 | 2.1e-06 | 1652 | 97 | 16 | ABL1,ACTN4,AKIP1,AXL,DOCK1,EFNA5,EPHA1,FBLN1,LAMB1,LAMB2,LIMS2,NTN4,PARVB,PDPN,RAC3,TRIOBP |
| GO_SYNAPSE_ASSEMBLY | 1.0e-07 | 2.1e-06 | 1652 | 178 | 22 | ADGRL3,BHLHB9,CEL,CUX2,DBNL,DKK1,DLG5,EFNA5,FLRT3,IL1RAPL2,LRRC24,NLGN3,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PLXNB1,PLXNB2,SEMA4A,SLITRK6,SPTBN2,WNT5A |
| GO_EPIDERMIS_DEVELOPMENT | 1.0e-07 | 2.3e-06 | 1652 | 464 | 39 | ABCA12,ALOX15B,APCDD1,ASAH1,BMP4,CELSR1,CYP27B1,DKK1,DLL1,EVPLL,FGF7,FLOT2,FZD6,HOXA7,HOXC13,HPSE,IGFBP5,KRT14,KRT5,KRT7,KRT81,KRTAP1-5,LAMA3,PCSK6,PLAAT4,PPARD,PPL,RIPOR2,SLITRK6,SPINK9,STS,TCHH,TGM1,TMC1,TP63,TRIOBP,VDR,WNT5A,ZDHHC21 |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 1.0e-07 | 2.2e-06 | 1652 | 940 | 63 | ACE2,ACKR3,ADARB1,ANPEP,AP2A1,APOBEC3C,APOBEC3G,APOE,APOL1,AXL,AZU1,BAD,CADM1,CD4,CFL1,CHMP6,CR1,CXCL12,DAG1,DPP4,EEA1,EIF2AK4,F2RL1,FBLN1,FKBP8,GPX1,HAVCR1,HYAL1,IFITM2,IFITM3,IKBKB,IKBKE,ITSN1,KAT2B,KRT7,MAPK3,MAVS,MXRA8,NFIA,NLRX1,PACS1,PIK3R1,PLSCR1,POLR2L,PRMT6,RBM15B,REST,RXRA,SLC20A2,SLC52A1,SMAD3,SSC5D,STAT3,TASOR,TLN1,TLR1,TP53,TRIM22,ULK2,USF2,VAMP8,VPS28,VPS37D |
| GO_MULTICELLULAR_ORGANISM_GROWTH | 1.0e-07 | 2.2e-06 | 1652 | 150 | 20 | ADARB1,AR,ATRN,CDKN1C,EN1,FKBP8,GDF5,GPAM,H3-3A,PKDCC,PLAC8,PLEKHA1,PPP1R13L,RARG,SLITRK6,SPTBN2,STAT3,TNS2,TP53,VIL1 |
| GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 1.0e-07 | 2.2e-06 | 1652 | 150 | 20 | AGT,ANGPT1,ENTPD5,ERBB2,F2R,F2RL1,FGR,GATA3,GPER1,IGF1R,MAPK3,PDGFC,PDGFD,PIK3CB,PIK3R1,PIK3R2,PIP4K2B,PLEKHA1,PLXNB1,PPARD |
| GO_SKELETAL_SYSTEM_MORPHOGENESIS | 1.0e-07 | 2.1e-06 | 1652 | 239 | 26 | AXIN2,BMP1,BMP4,COL12A1,COL14A1,COL1A1,EYA1,FGR,FMN1,HOXA4,HOXA7,HYAL1,IFT140,INPPL1,MEGF8,MGP,MMP2,NDST1,NOG,OSR1,PLEKHA1,RARG,SMAD3,THRA,TRIP11,WDR60 |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 1.0e-07 | 2.4e-06 | 1652 | 1200 | 75 | ADARB1,AGBL4,AGBL5,APOBEC3C,APOBEC3G,APOE,APOL1,APPL2,AXL,AZU1,C1R,C1RL,C3,C4A,C4B,CADM1,CD36,CD4,CFB,CR1,CRISP3,CRP,CTSS,CYBC1,CYP27B1,DEFB1,EIF2AK4,ERBIN,F2RL1,FBXO9,FGR,GATA3,GPAM,GPER1,HEXIM1,IFITM2,IFITM3,IGHV3-73,IKBKB,IKBKE,IL17RC,IL27RA,IL6R,JAGN1,JCHAIN,LYPD8,MAPK3,MAVS,MMP12,MR1,MSRB1,MUC15,MYD88,NLRX1,PAK3,PARP9,PLAC8,PLSCR1,PPM1B,PRKCD,PRKD1,PTPN22,PTPRC,RAF1,RARRES2,RTP4,SSC5D,STAR,TAB1,TLR1,TP53,TRIM22,TRIM29,TRIM59,WNT5A |
| GO_LEUKOCYTE_DIFFERENTIATION | 1.0e-07 | 2.3e-06 | 1652 | 520 | 42 | ABL1,ADA,AXL,BAD,BMP4,CCR7,CD4,CR1,CTLA4,DLL1,DOCK11,ERBB2,F2RL1,GATA3,GPR183,HOXA7,INHA,INPP5D,JAGN1,LEPR,LOXL3,LY6D,MAFB,MITF,NFAM1,PIAS3,PIK3R1,PRR7,PRXL2A,PTPN22,PTPRC,RORC,SEMA4A,SOCS5,STAT3,TAL1,TOB2,TP53,TRPM2,ZBTB16,ZBTB7A,ZBTB7B |
| GO_ALCOHOL_CATABOLIC_PROCESS | 2.0e-07 | 2.6e-06 | 1652 | 54 | 12 | ALDH3B1,APOE,CEL,IMPA2,INPP5A,INPP5J,NUDT3,SCARF1,SULT1A1,SULT1B1,SULT1E1,TRERF1 |
| GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | 2.0e-07 | 2.4e-06 | 1652 | 151 | 20 | ABL1,AGT,AR,BMP4,CAV3,CELSR1,CTSH,CTSZ,DAG1,DLG5,EDNRA,ENG,ESRP2,EYA1,NOG,PKD2,RSPO2,SEMA3E,VDR,WNT5A |
| GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS | 2.0e-07 | 2.5e-06 | 1652 | 111 | 17 | ANK2,CAPN3,CASQ1,CAV3,CNTNAP1,DAG1,FHOD3,KLHL41,LDB3,LMOD1,MYOM1,MYOM3,NEBL,OBSL1,PHLDB1,TMOD1,TPM1 |
| GO_MUSCLE_CELL_PROLIFERATION | 2.0e-07 | 2.5e-06 | 1652 | 241 | 26 | AGT,ANGPT1,APLN,BMP4,GPER1,HPGD,IGFBP5,IL6R,MEIS1,MMP2,MSTN,NOG,NPR1,NPR3,PDCD4,PDE1A,PDGFD,PPARD,RXRA,SELENON,SERPINF2,SIX5,STAT3,TGFBR3,TP53,TPM1 |
| GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 2.0e-07 | 2.7e-06 | 1652 | 211 | 24 | ABCA7,ABL1,ACKR3,ANGPT1,APOE,BMP4,CALCR,CCR7,CD36,CD4,F2R,F2RL1,GPER1,GPR183,HTR2C,MAP3K12,MAPK3,PDGFC,PDGFD,PTPN22,PTPRC,RAPGEF2,SERPINF2,TNFAIP8L3 |
| GO_RESPONSE_TO_XENOBIOTIC_STIMULUS | 2.0e-07 | 2.7e-06 | 1652 | 291 | 29 | ADA,ADGRL3,ALDH3A1,AOC2,AOC3,CALM3,CNR1,CYP2C18,CYP2E1,DNMT3A,FMO1,FMO2,FMO3,GPX1,GSTA1,GSTA2,GSTM2,MARC2,MGST2,MSTN,RORC,SELENON,SERPINF1,STAR,SULT1A1,SULT1B1,TP53,UGT1A6,UGT2B11 |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 2.0e-07 | 2.8e-06 | 1652 | 468 | 39 | ABL1,AGPAT1,AGT,ALOX15B,AZU1,C3,CADM1,CCBE1,CCR7,CD36,CD4,F2R,F2RL1,FFAR3,FGR,GATA3,HPSE,IL17RC,IL1R1,IL27RA,IL6R,LRRK2,MAPK3,MAVS,MMP12,MYD88,NFAM1,NLRX1,ORM1,PIK3R1,PLCB1,POLR2L,PTPN22,PTPRC,SERPINF2,SMAD3,STAT3,TLR1,WNT5A |
| GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 2.0e-07 | 2.9e-06 | 1652 | 378 | 34 | AGT,AP2A1,APOE,ASCL1,BHLHB9,BMP4,BMP5,BRINP3,CDKL5,CNR1,CUX2,CXCL12,DBNL,DKK1,DLG5,EFNA5,GDF5,IRX3,ITSN1,MEGF8,NCKIPSD,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,RAPGEF2,REST,SCARF1,SERPINF1,WASHC5,WNT5A |
| GO_POSITIVE_REGULATION_OF_SECRETION | 2.0e-07 | 2.7e-06 | 1652 | 431 | 37 | ABL1,AGT,ALOX15B,APLN,BAD,CADM1,CADPS2,CD33,CNR1,CXCL12,F2R,F2RL1,FGR,GATA3,GIP,GPER1,HFE,IL17RC,INHA,ITSN1,KCNN4,KMO,LRRK2,MAPK3,MAVS,MMP12,MYO18A,MYOM1,NMB,NPR1,OR51E2,ORM1,PPARD,PTPN22,TLR1,VAMP8,WNT5A |
| GO_T_CELL_ACTIVATION | 2.0e-07 | 2.8e-06 | 1652 | 468 | 39 | ABL1,ADA,BAD,BMP4,CCND3,CCR7,CD4,CD7,CR1,CTLA4,DLG5,DPP4,EIF2AK4,ERBB2,F2RL1,FLOT2,GATA3,GPAM,GPR183,HFE,HSH2D,LAX1,LEPR,LOXL3,MAFB,PAK3,PIK3R1,PRR7,PTPN22,PTPRC,RIPOR2,RORC,SEMA4A,SMAD3,SOCS5,STAT3,TP53,ZBTB16,ZBTB7B |
| GO_CELLULAR_RESPONSE_TO_XENOBIOTIC_STIMULUS | 2.0e-07 | 3.0e-06 | 1652 | 182 | 22 | ALDH3A1,AOC2,AOC3,CYP2C18,CYP2E1,FMO1,FMO2,FMO3,GSTA1,GSTA2,GSTM2,MARC2,MGST2,MSTN,RORC,SELENON,SERPINF1,STAR,SULT1A1,SULT1B1,UGT1A6,UGT2B11 |
| GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | 2.0e-07 | 2.9e-06 | 1652 | 212 | 24 | ADCY6,ADGRG1,ADGRG2,ADGRL3,APOE,CALCR,CD36,DEFB1,EIF4EBP2,EPHA5,GIP,GNAI1,GNAQ,GPER1,HTR2C,MC1R,MGRN1,NPR1,OR51E2,PDE3A,PTGER2,RAMP1,RAPGEF2,RXFP1 |
| GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 2.0e-07 | 2.9e-06 | 1652 | 167 | 21 | CADM1,CADM3,CDH6,CELSR1,CELSR3,EMB,FAT2,PCDH15,PCDH9,PCDHB11,PCDHB16,PCDHB4,PCDHB5,PCDHB8,PCDHGA2,PCDHGB6,PCDHGC3,PIK3CB,PLXNB2,PLXNB3,VSTM2L |
| GO_PROSTATE_GLAND_MORPHOGENESIS | 2.0e-07 | 2.9e-06 | 1652 | 28 | 9 | AR,BMP4,CRIP1,CYP7B1,NOG,RARG,RXRA,TP63,WNT5A |
| GO_REGULATION_OF_LEUKOCYTE_MIGRATION | 2.0e-07 | 3.0e-06 | 1652 | 197 | 23 | ADA,BMP5,CCL28,CCR7,CD99L2,CXCL12,F2RL1,GCSAM,HOXA7,IL1R1,IL27RA,IL6R,MAPK3,MMP28,MSTN,PADI2,PDGFD,PLCB1,RARRES2,RIPOR2,TP53,VEGFB,WNT5A |
| GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 2.0e-07 | 3.1e-06 | 1652 | 310 | 30 | ADCY6,ADGRG1,APOE,APPL2,ASCL1,COL3A1,CTSZ,DGUOK,DKK1,DLL1,EIF2AK4,INPP5J,IRX3,LRRK2,MEIS1,NLGN3,NOG,PTPRO,RAPGEF2,REST,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,STAT3,TP53,TRIM46,ULK2,WNT5A |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 2.0e-07 | 3.1e-06 | 1652 | 643 | 48 | AGT,APPL2,AZU1,C3,CADM1,CCR7,CD36,CNR1,CTSS,CXCL12,CYP27B1,ERBIN,F2RL1,FFAR3,HEXIM1,IKBKB,IKBKE,IL17RC,IL6R,LRRK2,MAPK3,MAVS,MEGF8,MGST2,MMP12,MSTN,MUC15,MYD88,NLRX1,PAK3,PARP9,PDCD4,PDGFD,PLSCR1,PRKCD,PRKD1,PTPN22,RAF1,RARRES2,RIPOR2,SCARF1,SERPINF2,SMAD3,TAB1,TLR1,VAMP8,VEGFB,WNT5A |
| GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 2.0e-07 | 3.1e-06 | 1652 | 327 | 31 | ABCA12,ANK2,ANXA13,AR,ARL13A,CACNB3,CACNG8,CAV3,DAG1,EHD2,FLOT2,GNAI1,GPER1,IKBKB,IQSEC2,KCNIP3,LYPD1,PACS1,PIK3R1,PKDCC,PLEKHF1,PPIL2,RAMP1,RAPGEF2,RTKN,SEC16A,STAC2,TTC7A,VAMP8,VIL1,WNK3 |
| GO_LIPID_PHOSPHORYLATION | 2.0e-07 | 3.4e-06 | 1652 | 66 | 13 | CERK,CISH,DGKA,DGKB,IMPA2,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,SOCS5,TTC7A |
| GO_REGULATION_OF_MEMBRANE_POTENTIAL | 2.0e-07 | 3.4e-06 | 1652 | 435 | 37 | ABCD1,ABL1,ANK2,ARL6IP5,ATP1A2,ATP1A4,BAD,BEST2,BOK,CACNB3,CAV3,CD36,CNR1,CNTNAP1,CTNNA3,CUX2,DMPK,GNAQ,GPER1,GRM1,HSH2D,KCNE3,KCNE4,KCNJ3,KCNK15,KCNMB3,KCNN4,LRRK2,NALCN,NLGN3,NNT,PIAS3,PIP5KL1,RGS7BP,SCN1A,SCN2B,STOX1 |
| GO_SKIN_DEVELOPMENT | 2.0e-07 | 3.4e-06 | 1652 | 417 | 36 | ABCA12,ADAMTS2,ALOX15B,APCDD1,ASAH1,CELSR1,COL1A1,COL1A2,COL3A1,COL5A2,CYP27B1,DKK1,DLL1,FGF7,FZD6,HOXA7,HOXC13,HPSE,IGFBP5,ITGB4,KRT14,KRT5,KRT7,KRT81,KRTAP1-5,PCSK6,PLAAT4,PPL,SLC27A4,SPINK9,TCHH,TGM1,TP63,VDR,WNT5A,ZDHHC21 |
| GO_ENDOCRINE_SYSTEM_DEVELOPMENT | 2.0e-07 | 3.5e-06 | 1652 | 127 | 18 | ASCL1,BAD,BMP4,BMP5,CDKN1C,DKK3,DLL1,GATA3,GIP,IL6R,MAPK3,NOG,RAF1,SIDT2,SMAD3,STRA6,THRA,WNT5A |
| GO_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS | 2.0e-07 | 3.5e-06 | 1652 | 169 | 21 | ABCD1,ACLY,ACSF3,ALOX15B,BDH2,CBR4,CYP2C18,CYP2E1,DAGLA,ELOVL3,ELOVL5,GPX1,GSTA1,HACD1,HACD2,HPGD,MAPK3,MGST2,PTGDS,SLC25A1,TBXAS1 |
| GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | 2.0e-07 | 3.5e-06 | 1652 | 114 | 17 | ACTN4,ANK2,CACNB3,CALM3,CASQ1,CTSS,GSTM2,JPH2,KCNE3,NLGN3,PDZK1,PKD2,PRKCD,STAC2,STIM1,STIMATE,WNK3 |
| GO_RESPONSE_TO_PEPTIDE_HORMONE | 2.0e-07 | 3.5e-06 | 1652 | 436 | 37 | ADCY6,AGT,APPL2,ATP6V0A4,BCAR1,BTG2,CCND3,COL1A1,CXCL12,DAG1,EIF4EBP2,FFAR3,GIP,GNAI1,GPER1,HADH,IGF1R,IGFBP5,INPPL1,KAT2B,KLF15,LPIN3,MSTN,NCOA5,PFKFB1,PIK3R1,PIK3R2,PIK3R3,PRKCD,PTPRA,RARRES2,SLC2A8,SPARC,STAR,STAT3,TGFBR3,ZBTB7B |
| GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 2.0e-07 | 3.6e-06 | 1652 | 141 | 19 | ABL1,ADGRG1,APOC3,APOE,ARHGEF17,ARHGEF25,COL3A1,F2R,F2RL1,FGD3,FGD4,ITSN1,KANK2,LPAR6,PLEKHG5,PLEKHG6,RAF1,RIPOR2,TRIO |
| GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | 2.0e-07 | 3.8e-06 | 1652 | 231 | 25 | AGT,ALPK3,BMP4,BMP5,CAV3,DKK1,DLL1,ENG,FHOD3,FOXH1,JPH2,MEIS1,MYOM1,MYOM3,NDUFV2,NEBL,NOG,OBSL1,PIN1,PPP1R13L,RXRA,TGFBR3,TNNC1,TPM1,WNT5A |
| GO_GASTRULATION | 2.0e-07 | 3.9e-06 | 1652 | 185 | 22 | APLN,ATOH8,BMP4,COL12A1,COL5A2,DAG1,DKK1,EXT2,EYA1,ITGB4,LAMA3,LAMB1,MAP2K5,MEGF8,MMP2,NOG,OSR1,PHLDB1,SMAD3,TAL1,TP53,WNT5A |
| GO_REGULATION_OF_CHEMOTAXIS | 2.0e-07 | 4.0e-06 | 1652 | 216 | 24 | ANGPT2,AZU1,CCR7,CXCL12,F2RL1,GPR183,IL6R,MAPK3,MEGF8,MMP28,MSTN,PADI2,PDGFD,PRKD1,PTPRO,RARRES2,RIPOR2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,VEGFB,WNT5A |
| GO_RESPONSE_TO_AMINO_ACID | 2.0e-07 | 4.0e-06 | 1652 | 115 | 17 | BAD,CFL1,COL1A1,COL1A2,COL3A1,COL5A2,DNMT3A,GIP,KLHL22,LAMTOR1,MMP2,NSMF,PDGFC,PDGFD,SESN1,SPAAR,TP53 |
| GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS | 3.0e-07 | 4.1e-06 | 1652 | 248 | 26 | AR,ATP1A2,BMP4,CYP7B1,FOXH1,GPAM,GPER1,KANK2,MSTN,NR2F2,NR2F6,OR51E2,PADI2,PMEPA1,PPARD,RARG,REST,RORC,RXRA,SERPINF1,STAR,THRA,TP63,VDR,ZBTB7A,ZNF366 |
| GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | 3.0e-07 | 4.1e-06 | 1652 | 232 | 25 | ABL1,ADAM12,AGGF1,ANGPT2,ANGPT4,C3,CCBE1,CTSH,DLL1,ENG,EPHA1,GPER1,HYAL1,IL6R,ITGB8,JMJD8,PDGFD,PRKD1,RAPGEF2,STAT3,STIM1,TIE1,TNFSF12,VEGFB,WNT5A |
| GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 3.0e-07 | 4.7e-06 | 1652 | 334 | 31 | ABL1,ADCY6,AGT,ANGPT1,ANGPT4,BMP4,DBNL,DUSP19,EFNA5,F2R,FPR1,GPRC5C,GRM1,IL6R,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,PAK3,PAK6,PDE6G,PDGFC,PIK3CB,PLCE1,PRKCD,PTPRC,RAF1,STRADA,TAB1,WNT5A |
| GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STIMULUS | 3.0e-07 | 4.8e-06 | 1652 | 68 | 13 | COL1A1,COL1A2,COL3A1,COL5A2,DNMT3A,KLHL22,LAMTOR1,MMP2,NSMF,PDGFC,PDGFD,SESN1,SPAAR |
| GO_MYOFIBRIL_ASSEMBLY | 3.0e-07 | 4.8e-06 | 1652 | 68 | 13 | CAPN3,CASQ1,CAV3,FHOD3,KLHL41,LDB3,LMOD1,MYOM1,MYOM3,NEBL,OBSL1,TMOD1,TPM1 |
| GO_MONOVALENT_INORGANIC_CATION_TRANSPORT | 3.0e-07 | 5.0e-06 | 1652 | 537 | 42 | ACTN4,ANK2,ATP1A2,ATP1A4,ATP6V0A4,CAV3,DMAC2L,DMPK,FXYD3,HECW2,KCNE3,KCNE4,KCNIP3,KCNJ16,KCNJ3,KCNK15,KCNMB3,KCNN4,KLHL3,NALCN,NNT,OSR1,PKD2,RHAG,SCN1A,SCN2B,SCNN1B,SLC12A9,SLC13A4,SLC15A2,SLC20A2,SLC22A5,SLC24A5,SLC2A8,SLC38A10,SLC5A2,SLC5A3,SLC9A9,TRPM2,UCP2,UTRN,WNK3 |
| GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT | 4.0e-07 | 5.5e-06 | 1652 | 58 | 12 | BAD,BMP4,BMP5,DLL1,RARG,RIPOR2,ROS1,SIDT2,SLITRK6,TMC1,TRIOBP,WNT5A |
| GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | 4.0e-07 | 5.4e-06 | 1652 | 204 | 23 | ADGRF5,APOE,AXL,BMP4,CNR1,CTLA4,CYGB,DLG5,ERBB2,FGR,GPER1,HFE,INHA,INPP5D,LAX1,LOXL3,PARP3,PRKCD,PTPN22,PTPRC,RIPOR2,SOCS5,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | 4.0e-07 | 5.6e-06 | 1652 | 48 | 11 | ADA,BMP5,CCL28,CXCL12,GCSAM,HOXA7,IL27RA,MMP28,PADI2,PLCB1,RIPOR2 |
| GO_PROSTATE_GLAND_DEVELOPMENT | 4.0e-07 | 5.6e-06 | 1652 | 48 | 11 | ALOX15B,AR,BMP4,CRIP1,CYP7B1,NOG,RARG,RXRA,SERPINF1,TP63,WNT5A |
| GO_CANONICAL_WNT_SIGNALING_PATHWAY | 4.0e-07 | 5.6e-06 | 1652 | 337 | 31 | APOE,AXIN2,COL1A1,DKK1,DKK3,DKKL1,FOLR1,FZD6,GATA3,GNAQ,INVS,JRK,LRRK2,MCC,MITF,NOG,NOTUM,PIN1,PPM1B,PTPRO,PTPRU,PYGO2,RARG,RBMS3,RSPO2,SMAD3,TBX18,TLE2,TLE5,WNT5A,ZBED3 |
| GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 4.0e-07 | 5.8e-06 | 1652 | 286 | 28 | ABL1,ADARB1,AJUBA,APOE,BMP4,CAV3,CDKN1C,CDKN2B,CHMP6,DUSP19,EPHA1,GMFB,GNAQ,HEXIM1,HEXIM2,IGF1R,KAT2B,LAX1,MLLT1,MSTN,NR2F2,PARP3,PDCD4,PRKCD,PTPN22,PTPRC,SOCS5,TP53 |
| GO_SPHINGOLIPID_METABOLIC_PROCESS | 4.0e-07 | 5.8e-06 | 1652 | 160 | 20 | ALDH3B1,ARSA,ASAH1,B3GALT4,B4GALT6,CERK,CERS6,ELOVL3,ELOVL5,HACD1,HACD2,ITGB8,PRKCD,PRKD1,SGPP2,SPTSSA,ST6GALNAC5,ST6GALNAC6,STS,SUMF1 |
| GO_FAT_CELL_DIFFERENTIATION | 4.0e-07 | 5.9e-06 | 1652 | 221 | 24 | ADGRF5,DKKL1,FBXO9,GATA3,GLIS1,GPER1,GPX1,HTR2C,LGALS12,MB,PEX11A,PLAC8,PLCB1,PPARD,RARRES2,RORC,SENP2,SMAD3,SULT1E1,TRIO,WNT5A,ZBTB16,ZBTB7A,ZBTB7B |
| GO_SPECIFICATION_OF_SYMMETRY | 4.0e-07 | 5.9e-06 | 1652 | 132 | 18 | ARMC4,BMP4,C9orf116,CCDC151,CCDC40,DAND5,DLL1,ENG,FOLR1,FOXH1,IFT140,MEGF8,NEK8,PCSK6,PKD2,SMAD3,TBC1D32,WNT5A |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 4.0e-07 | 6.1e-06 | 1652 | 410 | 35 | ABCD1,ADA,ANGPT2,APOE,APPL2,BACE1,CACNB3,CR1,CUEDC2,GATA3,GPER1,GPX1,KANK2,MMP12,MMP28,NLRX1,PADI2,PDCD4,PPARD,PPM1B,PRKCD,PTPRC,PTPRO,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SERPINF1,SERPINF2,SMAD3,SOCS5,TSPAN8,WFDC1,WNT5A |
| GO_PURINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 4.0e-07 | 6.3e-06 | 1652 | 206 | 23 | ACLY,ACSF3,ADA,ADCY6,AK1,AK3,CBR4,DGUOK,DMAC2L,ELOVL3,ELOVL5,HACD1,HACD2,NME3,NME4,NPR1,PANK1,PDP2,SHMT1,SLC25A1,SLC26A1,SLC26A2,STAT3 |
| GO_NEURAL_TUBE_DEVELOPMENT | 4.0e-07 | 6.4e-06 | 1652 | 161 | 20 | ABL1,BMP4,BMP5,CELSR1,CFL1,EN1,FKBP8,FOLR1,FZD6,IFT140,NOG,PKD2,PLXNB2,RARG,SEMA3C,SHROOM3,TBC1D32,TMEM107,WNT5A,ZNF358 |
| GO_REGULATION_OF_CELL_CELL_ADHESION | 4.0e-07 | 6.5e-06 | 1652 | 411 | 35 | ABL1,ADA,B4GALNT2,BAD,BMP4,CCL28,CCR7,CD4,CTLA4,CXCL12,DLG5,DPP4,EFNA5,ERBB2,FLOT2,GATA3,GPAM,HFE,LAX1,LOXL3,MAP2K5,PAK3,PDPN,PIK3R1,PRKCD,PTPN22,PTPRC,PTPRU,RIPOR2,RNASE10,SERPINF2,SOCS5,WNT5A,ZBTB16,ZBTB7B |
| GO_FACE_DEVELOPMENT | 4.0e-07 | 6.9e-06 | 1652 | 49 | 11 | COL1A1,CRISPLD2,DKK1,MAPK3,MMP2,NOG,PLEKHA1,RAF1,RARG,STRA6,WNT5A |
| GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 5.0e-07 | 6.9e-06 | 1652 | 223 | 24 | ADCY6,APOE,ASCL1,CTSZ,DGUOK,DKK1,DLL1,EIF2AK4,INPP5J,IRX3,LRRK2,MEIS1,NLGN3,PTPRO,RAPGEF2,REST,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,ULK2,WNT5A |
| GO_EAR_MORPHOGENESIS | 5.0e-07 | 7.0e-06 | 1652 | 120 | 17 | CELSR1,EYA1,FZD6,GATA3,MAFB,MAPK3,NOG,OSR1,POU3F4,RIPOR2,SLITRK6,STOX1,TRIOBP,TSHZ1,TTC39C,WNT5A,ZIC1 |
| GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 5.0e-07 | 7.0e-06 | 1652 | 431 | 36 | ABCD1,APOE,AREL1,ASB9,BAD,BTG2,CAV3,DET1,EIF2AK4,ENTPD5,GPD1,HECW2,LRRK2,MAPK3,NANOS1,NNT,PFKFB1,PIK3CB,PIP4K2B,PLEKHF1,PRKCD,PRKD1,RNF152,RNF180,SESN1,SOCS5,ST20,TFEB,TNFSF12,TRIM22,ULK2,VPS13C,VPS28,WNT5A,ZC3H12D,ZYG11B |
| GO_VERY_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS | 5.0e-07 | 7.2e-06 | 1652 | 31 | 9 | ABCD1,ACOT1,ACOT2,ELOVL3,ELOVL5,HACD1,HACD2,SLC27A2,SLC27A4 |
| GO_ANATOMICAL_STRUCTURE_MATURATION | 5.0e-07 | 7.7e-06 | 1652 | 163 | 20 | B4GALT6,C3,CDKN1C,CNTNAP2,DAG1,FAM210B,GATA3,GLDN,LRRK2,MMP2,NTN4,PDE3A,PLXNB1,RAC3,SCARF1,TAL1,TUT4,WASHC5,WNT5A,ZBTB7A |
| GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS | 5.0e-07 | 7.7e-06 | 1652 | 360 | 32 | AGT,ANXA8,ANXA8L1,BEX3,C3,C4A,C4B,CAAP1,CR1,CRIM1,CTSZ,GAS1,GPX1,HFE,ITIH3,LRRK2,MAP2K5,PANO1,PAPLN,RAF1,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SPINK9,SSPO,STYX,TP53,VIL1,WFDC1,WFDC8 |
| GO_ACTIN_MEDIATED_CELL_CONTRACTION | 5.0e-07 | 7.9e-06 | 1652 | 121 | 17 | ANK2,ATP1A2,CAV3,CTNNA3,FRMD6,KCNE3,KCNE4,KCNJ3,PDPN,SCN1A,SCN2B,TMOD1,TNNC1,TNNI2,TPM1,TPM4,VIL1 |
| GO_PROTEIN_KINASE_B_SIGNALING | 5.0e-07 | 7.9e-06 | 1652 | 274 | 27 | ANGPT1,AXL,CALCR,CAV3,CCR7,DAG1,ENG,ERBB2,FGF7,GATA3,GPER1,GPX1,HPSE,IGF1R,IGFBP5,ITSN1,MC1R,MSTN,PHLPP1,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PKHD1,PLEKHA1,STOX1,TNFAIP8L3 |
| GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 6.0e-07 | 8.3e-06 | 1652 | 258 | 26 | ABL1,ADARB1,AJUBA,APOE,BMP4,CAV3,CDKN1C,CDKN2B,CHMP6,DUSP19,EPHA1,GMFB,GNAQ,HEXIM1,HEXIM2,IGF1R,KAT2B,LAX1,MLLT1,MSTN,NR2F2,PDCD4,PRKCD,PTPN22,PTPRC,SOCS5 |
| GO_CARDIOCYTE_DIFFERENTIATION | 6.0e-07 | 8.4e-06 | 1652 | 164 | 20 | AGT,ALPK3,BMP4,CAV3,DKK1,DLL1,FHOD3,FOLR1,GPER1,MAPK3,MYOM1,MYOM3,NEBL,OBSL1,PDCD4,PIN1,REST,RXRA,SEMA3C,TGFBR3 |
| GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | 6.0e-07 | 8.5e-06 | 1652 | 292 | 28 | ABL1,ALOX15B,APLN,BAD,CADM1,CD33,F2R,F2RL1,FGR,GATA3,GIP,GPER1,HFE,IL17RC,ITSN1,KCNN4,LRRK2,MAPK3,MAVS,MMP12,MYO18A,MYOM1,OR51E2,ORM1,PPARD,PTPN22,TLR1,WNT5A |
| GO_ERYTHROCYTE_HOMEOSTASIS | 6.0e-07 | 8.8e-06 | 1652 | 122 | 17 | ADGRF5,ARID4A,AXL,BMP4,FAM210B,GATA3,INHA,INPP5D,MAFB,MB,P4HTM,RHAG,STAT3,TAL1,TGFBR3,THRA,ZBTB7A |
| GO_CELL_JUNCTION_ASSEMBLY | 7.0e-07 | 9.9e-06 | 1652 | 244 | 25 | ABL1,ACE2,ACTN1,ACTN4,AGT,AJUBA,ANK2,CDH6,CNTNAP1,DLG5,EFNA5,FMN1,FSCN1,GPM6B,IKBKB,ITGB4,KRT14,KRT5,LAMA3,LIMS2,NPHP1,PTPRO,RAPGEF2,SMAD3,TLN1 |
| GO_CHONDROCYTE_DIFFERENTIATION | 7.0e-07 | 9.9e-06 | 1652 | 123 | 17 | ADAMTS7,AXIN2,BMP4,COL12A1,COL14A1,EFEMP1,GDF5,NFIB,OSR1,PKDCC,RARG,SMAD3,SOX5,TGFBI,TRIP11,ZBTB16,ZNF219 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 7.0e-07 | 1.0e-05 | 1652 | 166 | 20 | ABL1,AGT,APLN,CREB3L1,DAND5,DKK1,EID2,GATA3,MTMR4,NOG,PBLD,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,TGFBR3,TP53,WNT5A,ZBTB7A |
| GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY | 7.0e-07 | 1.0e-05 | 1652 | 181 | 21 | AR,BMP4,CYP7B1,FOXH1,GPAM,GPER1,KANK2,NR2F2,NR2F6,OR51E2,PADI2,PMEPA1,PPARD,RARG,RORC,RXRA,THRA,TP63,VDR,ZBTB7A,ZNF366 |
| GO_NEPHRON_EPITHELIUM_DEVELOPMENT | 7.0e-07 | 1.0e-05 | 1652 | 110 | 16 | AGT,BMP4,DLL1,EYA1,FMN1,GATA3,IRX3,KLF15,KLHL3,LAMB2,MYO1E,NOG,OSR1,PKD2,POU3F3,PTPRO |
| GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 7.0e-07 | 1.0e-05 | 1652 | 278 | 27 | ACTN4,ALOX15B,AR,CYP27B1,CYP7B1,ERBIN,FOXH1,GPAM,GPER1,KANK2,NLRX1,NR2F2,NR2F6,PADI2,PMEPA1,PPARD,PTPN22,RARG,RORC,RXRA,STAT3,TAB1,THRA,TP63,VDR,ZBTB7A,ZNF366 |
| GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 7.0e-07 | 1.1e-05 | 1652 | 73 | 13 | ANK2,CACNB3,CALM3,CASQ1,CTSS,GSTM2,JPH2,KCNE3,NLGN3,PKD2,STAC2,STIM1,STIMATE |
| GO_REGULATION_OF_HEMOPOIESIS | 7.0e-07 | 1.1e-05 | 1652 | 477 | 38 | ABL1,ADA,AXL,BAD,BMP4,CD4,CR1,CTLA4,DLL1,ERBB2,FAM210B,GATA3,H3-3A,H3C6,HOXA7,INHA,INPP5D,KAT2B,LOXL3,MAFB,MEIS1,MITF,MYL9,NFAM1,NFE2,P4HTM,PIAS3,PIK3R1,PRMT6,PRXL2A,PTPRC,RARG,SOCS5,STAT3,TAL1,TOB2,ZBTB16,ZBTB7B |
| GO_SIGNAL_RELEASE | 7.0e-07 | 1.1e-05 | 1652 | 458 | 37 | AGT,APLN,BACE1,BAD,CADPS2,CALM3,CNR1,CPE,DPP4,EFNA5,EPHA5,FFAR3,GATA3,GIP,GPER1,HADH,HFE,HMGN3,HTR2C,INHA,ITSN1,JAGN1,KMO,LRRK2,NMB,PNKD,PPARD,RAB11FIP3,RAF1,REST,SIDT2,SNCAIP,SV2A,SYN2,SYT12,UNC13C,VAMP8 |
| GO_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | 7.0e-07 | 1.1e-05 | 1652 | 674 | 48 | ABL1,ADA,APPL2,ARPC5,BCAR1,BTN3A3,CACNB3,CCR7,CD33,CD36,CD4,CR1,CTLA4,CTSH,CTSS,DOCK1,ERBIN,F2RL1,FCGR2A,FGR,FPR1,GATA3,GCSAM,IGHV3-73,IKBKB,IKBKE,INPP5D,KCNN4,LAX1,MAPK3,MUC15,MYD88,NCKIPSD,NFAM1,NLRX1,PAK3,PIK3CB,PIK3R1,PIK3R2,PLEKHA1,PLSCR1,PRKCD,PTPN22,PTPRC,PVRIG,RAF1,TAB1,TLR1 |
| GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 8.0e-07 | 1.1e-05 | 1652 | 167 | 20 | APOE,AR,ATOH8,BMP4,CDKN1C,CDKN2B,GATA3,GDF5,LIMS2,MCC,NFIB,NR2F2,PBLD,PPARD,SERPINF1,SPARC,TGFBR3,VDR,WFDC1,WNT5A |
| GO_RESPONSE_TO_ANTIBIOTIC | 8.0e-07 | 1.1e-05 | 1652 | 331 | 30 | ABL1,ADA,ADCY6,AOC3,AXL,BAD,CLDN7,CNR1,COL1A1,CRIP1,CYP2E1,DNMT3A,EFNA5,GATA3,GNAI1,GPX1,HPGD,HYAL1,JAGN1,LRRK2,MB,MSTN,PDGFD,PLEKHA1,PRKCD,SPARC,STAR,STAT3,TP53,TRPM2 |
| GO_EXTRACELLULAR_MATRIX_ASSEMBLY | 8.0e-07 | 1.2e-05 | 1652 | 42 | 10 | AGT,COL1A2,DAG1,EFEMP2,GPM6B,LAMB1,LAMB2,NTN4,PHLDB1,SMAD3 |
| GO_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | 9.0e-07 | 1.2e-05 | 1652 | 33 | 9 | BMP1,BMP4,GDF5,PKDCC,SMAD3,SOX5,WNT5A,ZBTB16,ZNF219 |
| GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | 9.0e-07 | 1.2e-05 | 1652 | 52 | 11 | ADAMTS7,AXIN2,BMP4,EFEMP1,GDF5,PKDCC,RARG,SMAD3,SOX5,ZBTB16,ZNF219 |
| GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 9.0e-07 | 1.2e-05 | 1652 | 264 | 26 | AXL,CACNB3,CADPS2,CDKN2B,COL1A1,CYP27B1,DNAJC15,EIF2AK4,FOLR1,GDAP1,HFE,KANK2,LRRK2,MAP1LC3C,MAPK3,MIOS,P2RY11,PRKD1,PTPRC,RNF152,SESN1,TLE5,TP53,TXN2,USF2,VDR |
| GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 9.0e-07 | 1.3e-05 | 1652 | 184 | 21 | ADCY6,APOE,ARPIN,CTSZ,DGUOK,DKK1,INPP5J,LRRK2,NLGN3,PLXNB3,PRKCD,PTPRO,RAPGEF2,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,ULK2,WNT5A |
| GO_REGULATION_OF_AXONOGENESIS | 9.0e-07 | 1.3e-05 | 1652 | 184 | 21 | ABL1,APOE,CDKL5,CHN1,CXCL12,DBNL,EFNA5,MEGF8,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PTPRO,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,ULK2,WNT5A |
| GO_KIDNEY_EPITHELIUM_DEVELOPMENT | 9.0e-07 | 1.3e-05 | 1652 | 140 | 18 | AGT,BMP4,DLL1,EYA1,FMN1,GATA3,IRX3,KANK2,KLF15,KLHL3,LAMB2,MYO1E,NOG,OSR1,PKD2,POU3F3,PTPRO,SMAD3 |
| GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS | 9.0e-07 | 1.3e-05 | 1652 | 352 | 31 | AGT,ALDH9A1,ARL6IP5,ATP1A2,BACE1,CADPS2,CALM3,CD36,CNR1,DAGLA,DPYD,DPYS,GCHFR,GPER1,GPM6B,KMO,LRRK2,MAOA,PKD2,PNKD,RNF180,SARDH,SHMT1,SLC1A1,SMAD3,SNCAIP,SV2A,SYN2,SYT12,UNC13C,ZNF219 |
| GO_REGULATION_OF_OSSIFICATION | 9.0e-07 | 1.3e-05 | 1652 | 200 | 22 | AXIN2,BCOR,BMP4,CYP27B1,DKK1,GPM6B,IGFBP5,IL6R,MAPK3,MGP,NOG,OSR1,PKDCC,PRKD1,RANBP3L,REST,SMAD3,TOB2,TP63,TWIST2,WNT5A,ZBTB16 |
| GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 9.0e-07 | 1.3e-05 | 1652 | 232 | 24 | ABL1,ADA,APOE,AXL,BAD,CCR7,CD36,COL1A1,CYP2E1,GPX1,HYAL1,LRRK2,MAPK3,MB,MMP2,PDGFD,PKD2,PLEKHA1,PRKCD,SESN1,STAR,TP53,TPM1,TRPM2 |
| GO_EMBRYONIC_APPENDAGE_MORPHOGENESIS | 1.0e-06 | 1.3e-05 | 1652 | 126 | 17 | BMP4,DKK1,EN1,FZD6,GDF5,IFT140,MEGF8,NOG,OSR1,RARG,RSPO2,TBC1D32,TMEM107,TP63,WNT5A,ZBTB16,ZNF358 |
| GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 1.0e-06 | 1.3e-05 | 1652 | 216 | 23 | APCDD1,APOE,AXIN2,DKK1,DKK3,DKKL1,FZD6,INVS,MCC,NOG,NOTUM,PTPRO,PTPRU,RBMS3,RNF213,TAX1BP3,TBX18,TLE2,TLE5,TRABD2A,TRABD2B,TSKU,WNT5A |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 1.0e-06 | 1.3e-05 | 1652 | 804 | 54 | ABCD1,ACE2,ADA,AGT,APOBEC3G,APOE,APPL2,C3,CADM1,CCR7,CD36,CNR1,CR1,CTSS,CUEDC2,EIF2AK4,ERBIN,F2RL1,FFAR3,FGR,GATA3,GPER1,GPX1,HEXIM1,IKBKB,IKBKE,IL17RC,IL1R1,LRRK2,MAPK3,MAVS,MGST2,MMP12,MUC15,MYD88,NLRX1,PAK3,PARP9,PDCD4,PLSCR1,PPARD,PPM1B,PRKCD,PTPN22,PTPRC,RAF1,SERPINF1,SMAD3,SOCS5,TAB1,TLR1,VAMP8,WFDC1,WNT5A |
| GO_ARTERY_DEVELOPMENT | 1.0e-06 | 1.5e-05 | 1652 | 100 | 15 | ADGRF5,APOE,BMP4,COL3A1,ENG,EYA1,FOLR1,FOXH1,HPGD,MYLK,NDST1,NOG,PKD2,STRA6,TAB1 |
| GO_ARTERY_MORPHOGENESIS | 1.0e-06 | 1.4e-05 | 1652 | 75 | 13 | ADGRF5,APOE,BMP4,COL3A1,ENG,EYA1,FOLR1,FOXH1,HPGD,MYLK,NOG,PKD2,STRA6 |
| GO_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY | 1.1e-06 | 1.5e-05 | 1652 | 64 | 12 | ANGPT2,APOL2,AR,CNR1,CYP27B1,LDOC1,MAPK3,MMP7,NR2F2,PPARD,RXRA,VDR |
| GO_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 1.1e-06 | 1.5e-05 | 1652 | 250 | 25 | ABL1,AGT,AP2A1,AR,BCOR,BMP4,CAV3,CELSR1,CELSR3,DKK1,ENG,EYA1,FGF7,FZD6,GATA3,LIMS2,NFIB,NOG,NTN4,RSPO2,RXRA,SEMA3C,STOX1,VDR,WNT5A |
| GO_REGULATION_OF_CELL_SHAPE | 1.1e-06 | 1.5e-05 | 1652 | 156 | 19 | DAG1,FGD3,FGD4,FGR,PALM2AKAP2,PALMD,PARVB,PDPN,PLXNB1,PLXNB2,PLXNB3,PLXNC1,RAC3,RHOBTB2,SEMA3E,SEMA4A,SHROOM3,TPM1,VIL1 |
| GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | 1.2e-06 | 1.7e-05 | 1652 | 219 | 23 | AXIN2,BMP4,BTG2,CELSR1,DKK1,DLL1,EN1,FOXH1,HOXA4,HOXA7,HOXC13,NOG,NR2F2,OSR1,PCSK6,RARG,SEMA3C,SMAD3,TBX18,TP53,TSHZ1,WNT5A,ZBTB16 |
| GO_CYTOKINE_SECRETION | 1.2e-06 | 1.7e-05 | 1652 | 252 | 25 | ABL1,AGT,ALOX15B,ANGPT1,CADM1,CCR7,CD36,CRP,F2R,F2RL1,FGR,GATA3,GPAM,IL17RC,IL27RA,LRRK2,MAPK3,MAVS,MMP12,ORM1,PTPN22,SSC5D,TLR1,WNT5A,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 1.2e-06 | 1.6e-05 | 1652 | 101 | 15 | ACADL,AP2A1,APOC3,APOE,APPL2,BMP5,CNR1,CYP27B1,DKK3,DKKL1,LEPR,PFKFB1,REST,STAT3,TP53 |
| GO_PLATELET_DEGRANULATION | 1.2e-06 | 1.6e-05 | 1652 | 128 | 17 | ACTN1,ACTN4,CD36,CLEC3B,ISLR,ITIH3,ORM1,RARRES2,SELENOP,SERPINA3,SERPINF2,SPARC,TAGLN2,TEX264,TLN1,VEGFB,VWF |
| GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | 1.3e-06 | 1.8e-05 | 1652 | 115 | 16 | ABL1,ASCL1,BAD,BMP4,BMP5,DLL1,RARG,RIPOR2,ROS1,RXRA,SIDT2,SLITRK6,TMC1,TP63,TRIOBP,WNT5A |
| GO_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT | 1.3e-06 | 1.8e-05 | 1652 | 115 | 16 | ANO2,ANO8,APOL1,BEST2,BEST4,CLCA2,CLCNKA,CLIC3,FXYD3,SLC12A9,SLC13A4,SLC1A1,SLC20A2,SLC26A1,SLC26A2,SLC37A2 |
| GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | 1.3e-06 | 1.8e-05 | 1652 | 54 | 11 | ABL1,CALCR,CALM3,CAPN3,CASQ1,CD4,F2R,GPER1,GSTM2,JPH2,PKD2 |
| GO_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 1.3e-06 | 1.8e-05 | 1652 | 115 | 16 | ABL1,CCDC80,CCL28,CCR7,CD36,DAG1,DOCK1,EGFL6,EPHA1,FBLN2,FMN1,LIMS2,RAC3,SMAD3,TRIOBP,UTRN |
| GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION | 1.3e-06 | 1.8e-05 | 1652 | 54 | 11 | ANKRD2,BMP4,CAPN3,DLL1,FLOT2,KLHL41,MSTN,PLCB1,PPARD,RANBP3L,RIPOR2 |
| GO_RESPONSE_TO_NUTRIENT | 1.3e-06 | 1.8e-05 | 1652 | 220 | 23 | ADA,AGL,ALDH3A1,ASCL1,CCL28,CD4,CDKN2B,CNR1,COL1A1,CYP27B1,DNMT3A,FOLR1,GDAP1,KANK2,NNT,P2RY11,PPARD,SLC27A4,SPARC,STAR,TP53,USF2,VDR |
| GO_SKELETAL_MUSCLE_CONTRACTION | 1.3e-06 | 1.8e-05 | 1652 | 44 | 10 | CASQ1,CAV3,CCDC78,DMPK,GSTM2,MB,RCSD1,STAC2,TNNC1,TNNI2 |
| GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORT | 1.3e-06 | 1.8e-05 | 1652 | 143 | 18 | ACTN4,ATP1A2,ATP1A4,CAV3,FXYD3,HECW2,NALCN,OSR1,PKD2,SCN1A,SCN2B,SCNN1B,SLC20A2,SLC24A5,SLC9A9,TRPM2,UTRN,WNK3 |
| GO_CELL_CHEMOTAXIS | 1.5e-06 | 2.0e-05 | 1652 | 306 | 28 | ACKR3,AZU1,BCAR1,CCL28,CCR7,CXCL12,CXCR5,CYP7B1,F2RL1,GPR183,HSD3B7,IL17RC,IL6R,MAPK3,MMP28,MSTN,PADI2,PDGFD,PLEKHG5,PLXNB3,PRKCD,PRKD1,PTPRO,RARRES2,RIPOR2,TRPM2,VEGFB,WNT5A |
| GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 1.5e-06 | 2.0e-05 | 1652 | 289 | 27 | AGT,AP2A1,APOE,BHLHB9,BMP5,CDKL5,CNR1,CUX2,CXCL12,DBNL,DLG5,EFNA5,ITSN1,MEGF8,NCKIPSD,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,PRKD1,RAPGEF2,SCARF1,SERPINF1,WASHC5,WNT5A |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 1.5e-06 | 2.0e-05 | 1652 | 944 | 60 | ABCA7,ACOT2,AGT,ANGPT1,ANK2,APPL2,ARL13A,BAD,BMP4,CACNG8,CALM3,CD36,COL1A1,CPE,DAG1,DDO,DECR2,DNAJC15,DNM1,ECI2,FAM53A,GDAP1,HSPA1L,IFT140,IQSEC2,LRRK2,MAVS,MMP12,NUDCD3,OBSL1,PACS1,PARP3,PARP9,PEX13,PIK3R1,PIK3R2,PIN1,PRKCD,RAB11FIP3,RTKN,SCP2,SEC16A,SLC27A2,SMAD3,STAT3,SUN2,TASOR,TBC1D32,TMEM107,TP53,TP63,TRIM29,UBXN2B,VPS13A,VPS13C,VPS28,VPS37D,ZBTB16,ZBTB7A,ZIC1 |
| GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_CIRCULATORY_RENIN_ANGIOTENSIN | 1.5e-06 | 2.0e-05 | 1652 | 19 | 7 | ACE2,CPA3,CTSZ,F2R,F2RL1,MME,OR51E2 |
| GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 1.6e-06 | 2.1e-05 | 1652 | 307 | 28 | ABCD1,ANGPT1,APPL2,AXL,CD33,CUEDC2,DLL1,ERBIN,F2RL1,GATA3,HFE,IKBKE,IL27RA,INHA,INPP5D,MAP2K5,MAVS,MC1R,NLRX1,ORM1,PDCD4,PIN1,PPM1B,PTPN22,PTPRC,SOCS5,SSC5D,UBA7 |
| GO_NEURON_MIGRATION | 1.6e-06 | 2.2e-05 | 1652 | 160 | 19 | ADGRG1,ADGRL3,APBB2,ASCL1,AXL,CDKL5,CELSR1,CELSR3,COL3A1,CXCL12,GATA3,NAV1,NR2F2,NSMF,PEX13,PLXNB2,RAPGEF2,STAT3,TRIM46 |
| GO_REGULATION_OF_TRANSPORTER_ACTIVITY | 1.6e-06 | 2.2e-05 | 1652 | 290 | 27 | ACTN4,ANK2,ATP1A2,CACNB3,CACNG8,CALM3,CASQ1,CAV3,CTSS,FXYD3,GSTM2,HECW2,JPH2,KCNE3,KCNE4,NLGN3,OSR1,PDZK1,PKD2,PRKCD,SCN2B,SELENON,STAC2,STIM1,STIMATE,UTRN,WNK3 |
| GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS | 1.7e-06 | 2.2e-05 | 1652 | 191 | 21 | ACADL,ALDH1L1,ALDH9A1,CKB,FOLH1,FOLR1,GATA3,GPX1,GSTA1,GSTA2,GSTM2,GSTT2B,HOGA1,KYAT1,MGST2,OSBPL5,PLSCR1,PRODH,SARDH,SHMT1,SULT1B1 |
| GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | 1.7e-06 | 2.3e-05 | 1652 | 91 | 14 | ADGRF5,CCR7,CISH,FGR,HTR2C,MTMR4,PIK3R1,PIK3R2,PIK3R3,PRKCD,PRKD1,SOCS5,TNFAIP8L3,WDR81 |
| GO_T_CELL_DIFFERENTIATION | 1.7e-06 | 2.3e-05 | 1652 | 240 | 24 | ABL1,ADA,BAD,BMP4,CCR7,CD4,CR1,CTLA4,ERBB2,GATA3,GPR183,LEPR,LOXL3,MAFB,PRR7,PTPN22,PTPRC,RORC,SEMA4A,SOCS5,STAT3,TP53,ZBTB16,ZBTB7B |
| GO_LATERAL_SPROUTING_FROM_AN_EPITHELIUM | 1.8e-06 | 2.4e-05 | 1652 | 13 | 6 | AR,BMP4,CELSR1,NOG,TP63,WNT5A |
| GO_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS | 1.8e-06 | 2.4e-05 | 1652 | 27 | 8 | BMP5,CYP27B1,DKK3,DKKL1,FFAR3,REST,TRERF1,VDR |
| GO_RIBOSE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 1.8e-06 | 2.4e-05 | 1652 | 192 | 21 | ACLY,ACSF3,ADCY6,AK1,AK3,CBR4,CTPS2,DMAC2L,ELOVL3,ELOVL5,HACD1,HACD2,NME3,NME4,NPR1,PANK1,PDP2,SLC25A1,SLC26A1,SLC26A2,STAT3 |
| GO_ACTIN_FILAMENT_POLYMERIZATION | 1.9e-06 | 2.5e-05 | 1652 | 177 | 20 | ACTR3B,ARPC5,ARPIN,CCR7,CORO7,DBNL,FHOD3,FMN1,GMFB,LMOD1,MSRB1,MSRB2,PAK3,PRKCD,SPTBN2,TMOD1,TMSB15B,TRIOBP,VIL1,VILL |
| GO_CARBOHYDRATE_HOMEOSTASIS | 1.9e-06 | 2.5e-05 | 1652 | 241 | 24 | ADGRF5,APPL2,ASPSCR1,BAD,CAV3,CNR1,EFNA5,EPHA5,GPER1,HMGN3,IGF1R,IGFBP5,JAGN1,KLF15,LEPR,NCOA5,NMB,PIK3R1,PIK3R2,RAF1,SERPINF1,SIDT2,STAR,STAT3 |
| GO_MYELOID_CELL_HOMEOSTASIS | 1.9e-06 | 2.5e-05 | 1652 | 147 | 18 | ADGRF5,ARID4A,AXL,BMP4,FAM210B,GATA3,INHA,INPP5D,MAFB,MB,P4HTM,PIK3CB,RHAG,STAT3,TAL1,TGFBR3,THRA,ZBTB7A |
| GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | 1.9e-06 | 2.5e-05 | 1652 | 636 | 45 | ABCD1,ADA,ALDH1L1,ANGEL2,APOBEC3C,APOBEC3G,APOE,AXIN2,BTG2,CEL,CNOT11,CSDC2,CYP27B1,DPYD,DPYS,ENTPD4,ENTPD5,GPX1,HPD,KMO,KYAT1,MAOA,MYD88,NANOS1,NEIL1,NUDT12,NUDT13,NUDT3,PAN2,PCBP4,PDE1A,PDE7B,PDE8B,PRKCD,PRODH,PYM1,SCARF1,SIDT2,ST20,STS,SULT1E1,TNKS1BP1,TRERF1,TUT4,ZC3H12D |
| GO_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 1.9e-06 | 2.5e-05 | 1652 | 56 | 11 | ABL1,AGT,AR,BMP4,CAV3,FGF7,LRRK2,NOG,NTN4,RXRA,WNT5A |
| GO_GAMETE_GENERATION | 2.0e-06 | 2.6e-05 | 1652 | 698 | 48 | ADAMTS2,ADGRG2,ANGPT2,AR,ARID4A,ATP1A4,AXL,BAD,BMP4,C9orf24,CADM1,CCDC87,CNR1,DEFB1,DNMT3A,H3-3A,HERC2,HPGD,KLHL10,LIMK2,LRRK2,NPHP1,PDE3A,PLEKHA1,PYGO2,ROS1,SERPINA5,SIX5,SLC2A14,SLC2A8,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,SPIN1,SPIN2B,TDRD9,TMEM203,TOB2,TP63,TSNAXIP1,TSPAN8,TUT4,VCX,WASHC5,ZBTB16,ZNF541 |
| GO_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | 2.0e-06 | 2.6e-05 | 1652 | 105 | 15 | AOC2,CYP2E1,GATA3,MAOA,MC1R,NPR1,PNKD,RAPGEF2,RNF180,SLC24A5,SNCAIP,STAR,SULT1A1,SULT1B1,WNT5A |
| GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 2.0e-06 | 2.6e-05 | 1652 | 259 | 25 | AJUBA,BMP4,DBNL,DKK1,DUSP19,ERBB2,F2R,FPR1,GRM1,LRRK2,MAP2K5,MAP3K11,MAP3K12,MAPK3,NEK10,PAK3,PDE6G,PDGFC,PDGFD,PIK3CB,PLCE1,PTPRC,RAF1,TAB1,WNT5A |
| GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 2.0e-06 | 2.6e-05 | 1652 | 276 | 26 | ABL1,ADA,AXL,BAD,BMP4,CD4,CR1,CTLA4,ERBB2,GATA3,HOXA7,INHA,INPP5D,LOXL3,MAFB,MITF,NFAM1,PIAS3,PIK3R1,PRXL2A,PTPRC,SOCS5,TAL1,TOB2,ZBTB16,ZBTB7B |
| GO_RESPONSE_TO_VITAMIN | 2.0e-06 | 2.6e-05 | 1652 | 92 | 14 | ADA,ASCL1,CD4,COL1A1,CYP27B1,DNMT3A,FOLR1,GDAP1,KANK2,NNT,PPARD,SPARC,TP53,VDR |
| GO_SPHINGOLIPID_BIOSYNTHETIC_PROCESS | 2.0e-06 | 2.6e-05 | 1652 | 105 | 15 | ALDH3B1,ASAH1,B3GALT4,B4GALT6,CERS6,ELOVL3,ELOVL5,HACD1,HACD2,PRKCD,PRKD1,SGPP2,SPTSSA,ST6GALNAC5,ST6GALNAC6 |
| GO_CARBOHYDRATE_TRANSPORT | 2.1e-06 | 2.8e-05 | 1652 | 148 | 18 | APPL2,AQP7,ASPSCR1,C3,EDNRA,GIP,KLF15,MFSD4A,PIK3R1,PPARD,SLC2A14,SLC2A8,SLC35A4,SLC35D1,SLC37A2,SLC5A2,SLC5A3,VIL1 |
| GO_CELL_MATRIX_ADHESION | 2.1e-06 | 2.7e-05 | 1652 | 226 | 23 | ABL1,ACTN1,AJUBA,CCL28,CCR7,CD36,COL3A1,DAG1,EFNA5,EPHA1,FMN1,GPM6B,HOXA7,HPSE,ITGA11,ITGB4,MMP12,MSLN,PIK3CB,PIK3R1,SEMA3E,SMAD3,UTRN |
| GO_NUCLEOSIDE_BISPHOSPHATE_BIOSYNTHETIC_PROCESS | 2.1e-06 | 2.8e-05 | 1652 | 68 | 12 | ACLY,ACSF3,CBR4,ELOVL3,ELOVL5,HACD1,HACD2,PANK1,PDP2,SLC25A1,SLC26A1,SLC26A2 |
| GO_REGULATION_OF_CELL_MATRIX_ADHESION | 2.1e-06 | 2.7e-05 | 1652 | 119 | 16 | ABL1,CCL28,CCR7,CD36,DAG1,EFNA5,EPHA1,FMN1,GPM6B,HOXA7,MMP12,PIK3CB,PIK3R1,SEMA3E,SMAD3,UTRN |
| GO_RESPONSE_TO_RADIATION | 2.1e-06 | 2.8e-05 | 1652 | 441 | 35 | ABCA4,ANGPT2,ATP1A2,BACE1,C9orf116,COL3A1,CRIP1,CXCL12,DNMT3A,EIF2AK4,ERCC5,EYA1,GATA3,GNAQ,GPX1,GTF2H5,HYAL1,INTS3,KRT14,MC1R,MME,NLGN3,NPHP1,NR2F6,OPN3,PDE6A,PDE6G,PIK3R1,PPP1CB,PTPRC,ST20,STAR,SYNPO,TNKS1BP1,TP53 |
| GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | 2.3e-06 | 3.0e-05 | 1652 | 211 | 22 | AGL,AP2A1,B3GNT10,B4GALT1,CHST14,CHST9,ENO3,EXT2,GPD1,GPER1,GYG2,IMPA2,ISYNA1,KAT2B,LEPR,NDST1,NDST4,PFKFB1,PPP1CB,SLC25A1,ST6GALNAC5,ST6GALNAC6 |
| GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 2.3e-06 | 2.9e-05 | 1652 | 500 | 38 | ABL1,ADA,APPL2,ARPC5,BCAR1,BTN3A3,CACNB3,CCR7,CD4,CR1,CTLA4,DOCK1,FCGR2A,FGR,FPR1,GATA3,GCSAM,IGHV3-73,IKBKB,INPP5D,KCNN4,LAX1,MAPK3,MUC15,NCKIPSD,NFAM1,PAK3,PIK3CB,PIK3R1,PIK3R2,PLEKHA1,PLSCR1,PRKCD,PTPN22,PTPRC,PVRIG,RAF1,TAB1 |
| GO_MULTICELLULAR_ORGANISMAL_MOVEMENT | 2.3e-06 | 2.9e-05 | 1652 | 57 | 11 | ASCL1,CASQ1,CAV3,CCDC78,DMPK,GSTM2,MB,RCSD1,STAC2,TNNC1,TNNI2 |
| GO_REGULATION_OF_CELLULAR_EXTRAVASATION | 2.4e-06 | 3.1e-05 | 1652 | 28 | 8 | CCL28,CD99L2,CXCL12,IL1R1,IL27RA,PDGFD,PLCB1,RIPOR2 |
| GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT | 2.4e-06 | 3.1e-05 | 1652 | 28 | 8 | ACTA2,ANGPT1,ANGPT2,BMP4,IL6R,OSR1,PDGFD,PKD2 |
| GO_PROTEIN_CATABOLIC_PROCESS | 2.5e-06 | 3.2e-05 | 1652 | 938 | 59 | ADAMTS7,ANAPC11,ANAPC16,AP2A1,APOE,AREL1,ASB9,BACE1,CAPN3,CAV3,CHMP6,CTSH,CTSO,CTSS,CTSZ,CUL9,DET1,EDEM3,FBXL15,FBXL17,FBXL19,FBXL22,FBXO9,GPX1,HECW2,HERC2,HFE,HPSE,KLHL22,KLHL3,LNPEP,LRRK2,LYPLA2,MMP12,NEDD8,NOTUM,OMA1,PANO1,PIN1,PLEKHG5,RNF150,RNF180,RNF213,SGSH,SMAD3,SOCS5,STYX,TMEM129,TNFSF12,UBA7,UBE3B,UBXN2B,USP22,VPS28,VPS37D,WDR81,WNT5A,ZRANB1,ZYG11B |
| GO_ACUTE_PHASE_RESPONSE | 2.6e-06 | 3.3e-05 | 1652 | 47 | 10 | APOL2,CNR1,CRP,HFE,IL6R,ORM1,PLSCR1,SERPINA3,SERPINF2,STAT3 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 2.6e-06 | 3.3e-05 | 1652 | 351 | 30 | ABCD1,ABL1,ALDH3B1,ANKRD2,ARL6IP5,AXL,BAD,CAPN3,CD36,EFHD1,GPX1,GPX8,LANCL1,LRRK2,MAPK3,MMP2,MYLK,PDGFD,PKD2,PLEKHA1,PRKCD,PRKD1,PRODH,RCSD1,REST,SELENON,STOX1,TP53,TPM1,TRPM2 |
| GO_DEVELOPMENTAL_MATURATION | 2.6e-06 | 3.3e-05 | 1652 | 280 | 26 | ASCL1,AXL,B4GALT6,BLOC1S5,C3,CDKN1C,CNTNAP2,DAG1,DEFB1,FAM210B,GATA3,GLDN,LRRK2,MMP2,NFIA,NTN4,PDE3A,PLXNB1,RAC3,SCARF1,TAL1,TUT4,UNC13C,WASHC5,WNT5A,ZBTB7A |
| GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | 2.6e-06 | 3.3e-05 | 1652 | 94 | 14 | ACE2,AGT,AR,CPA3,CTSZ,F2R,F2RL1,MME,NAV2,NR2F2,OR51E2,PTPRO,SERPINF2,TPM1 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 2.7e-06 | 3.4e-05 | 1652 | 603 | 43 | ABL1,ACKR3,AGT,ANKRD2,AR,ARL6IP5,BAD,BEX3,BMP4,BMP5,BOK,CAAP1,CREB3L1,CRIP1,CTSH,CXCL12,EYA1,FAIM,GPER1,GPX1,IKBKE,IL6R,LGALS12,LRRK2,MAP2K5,NACC2,NOG,PIK3R1,PLEKHF1,PPARD,PRKCD,PRODH,PRR7,PTPRC,RAF1,SMAD3,ST20,TMEM117,TNFRSF10C,TNFRSF25,TNFSF12,TP53,TP63 |
| GO_COGNITION | 2.7e-06 | 3.4e-05 | 1652 | 298 | 27 | ABCA7,AFF2,AGT,APOE,ATP1A2,BHLHB9,BTG2,CNR1,CNTNAP2,CUX2,DKK1,EIF2AK4,EIF4EBP2,EN1,GIP,GMFB,LHX8,METTL23,MME,NLGN3,PAK6,PLCB1,SERPINF1,SHROOM4,STRA6,SYNPO,THRA |
| GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM | 2.8e-06 | 3.6e-05 | 1652 | 151 | 18 | ABL1,AR,BMP4,BMP5,CELSR1,CFL1,FOLR1,FZD6,GATA3,IRX3,NOG,OSR1,PLXNB2,RARG,SHROOM3,TBX18,TP63,WNT5A |
| GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 2.8e-06 | 3.6e-05 | 1652 | 264 | 25 | AGT,ANXA8,ANXA8L1,BEX3,C3,C4A,C4B,CAAP1,CR1,CRIM1,GPX1,ITIH3,MAP2K5,PAPLN,RAF1,SERPINA3,SERPINA5,SERPINA6,SERPINF1,SERPINF2,SPINK9,SSPO,VIL1,WFDC1,WFDC8 |
| GO_AXON_EXTENSION | 2.9e-06 | 3.6e-05 | 1652 | 122 | 16 | ABL1,APOE,CDKL5,CXCL12,DBNL,LAMB2,MEGF8,NLGN3,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPG11,TRIM46,ULK2,WNT5A |
| GO_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 3.0e-06 | 3.8e-05 | 1652 | 282 | 26 | AGL,AOAH,B3GNT10,B4GALT1,BAD,EXT2,FCSK,GPER1,GYG2,IDNK,IMPA2,INPP5A,INPP5J,ISYNA1,KAT2B,LEPR,MYOF,NDST1,NDST4,PFKFB1,PPP1CB,PYGM,RORC,SLC5A3,STAT3,TP53 |
| GO_RESPONSE_TO_OXYGEN_LEVELS | 3.0e-06 | 3.8e-05 | 1652 | 391 | 32 | ACTN4,ADA,AJUBA,ALDH3A1,ANGPT2,ANGPT4,BAD,CACNB3,CIAO3,COL1A1,CXCL12,CYGB,DNMT3A,DPP4,EDNRA,FUNDC1,MB,MMP2,PDLIM1,PIN1,PPARD,PSEN2,RAF1,REST,SLC2A8,SMAD3,STOX1,TGFBR3,TP53,TXN2,UCP2,VEGFB |
| GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION | 3.1e-06 | 3.9e-05 | 1652 | 48 | 10 | ASCL1,BAD,BMP4,BMP5,DLL1,RARG,RXRA,SIDT2,TP63,WNT5A |
| GO_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 3.1e-06 | 3.9e-05 | 1652 | 152 | 18 | ADCY6,APOE,CTSZ,DGUOK,DKK1,INPP5J,LRRK2,NLGN3,PTPRO,RAPGEF2,RTN4RL1,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,ULK2,WNT5A |
| GO_REGULATION_OF_HORMONE_METABOLIC_PROCESS | 3.1e-06 | 3.9e-05 | 1652 | 38 | 9 | BMP5,CYP27B1,DKK3,DKKL1,FFAR3,GATA3,REST,TRERF1,VDR |
| GO_ACUTE_INFLAMMATORY_RESPONSE | 3.2e-06 | 4.0e-05 | 1652 | 109 | 15 | APOL2,B4GALT1,C3,CCR7,CNR1,CRP,FFAR3,GATA3,HFE,IL6R,ORM1,PLSCR1,SERPINA3,SERPINF2,STAT3 |
| GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS | 3.2e-06 | 4.0e-05 | 1652 | 29 | 8 | BMP4,CELSR1,CTSH,CTSZ,DAG1,DLG5,ESRP2,RSPO2 |
| GO_HORMONE_MEDIATED_SIGNALING_PATHWAY | 3.2e-06 | 4.0e-05 | 1652 | 232 | 23 | APPL2,AR,BMP4,CYP7B1,FOXH1,GPAM,GPER1,KANK2,NR2F2,NR2F6,OR51E2,PADI2,PMEPA1,PPARD,RARG,RORC,RXFP1,RXRA,THRA,TP63,VDR,ZBTB7A,ZNF366 |
| GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 3.3e-06 | 4.1e-05 | 1652 | 96 | 14 | ANK2,ATP1A2,CACNB3,CALM3,CASQ1,CAV3,GSTM2,JPH2,KCNE3,PKD2,SELENON,STAC2,STIM1,STIMATE |
| GO_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT | 3.3e-06 | 4.1e-05 | 1652 | 21 | 7 | BMP4,COL3A1,ENG,MYLK,OSR1,PKD2,STRA6 |
| GO_STEROL_METABOLIC_PROCESS | 3.4e-06 | 4.2e-05 | 1652 | 168 | 19 | ACADL,ACLY,APOE,APOL1,APOL2,CEL,CETP,CYP7B1,EBPL,GPAM,LEPR,LIMA1,OSBPL5,PPARD,RXRA,SCARF1,STAR,TRERF1,TTC39B |
| GO_CELLULAR_AMINO_ACID_CATABOLIC_PROCESS | 3.5e-06 | 4.4e-05 | 1652 | 124 | 16 | AASS,ADO,AUH,DBT,DDO,GPT,HOGA1,HPD,IVD,KMO,KYAT1,MCCC1,PRODH,SARDH,SHMT1,TXN2 |
| GO_DEVELOPMENTAL_CELL_GROWTH | 3.5e-06 | 4.3e-05 | 1652 | 233 | 23 | ABL1,AGT,APOE,CAV3,CDKL5,CXCL12,DBNL,EFNA5,EIF2AK4,FLRT3,LAMB2,MEGF8,NLGN3,PIN1,RARG,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPG11,TRIM46,ULK2,WNT5A |
| GO_NEGATIVE_REGULATION_OF_CELL_GROWTH | 3.5e-06 | 4.3e-05 | 1652 | 184 | 20 | AGT,APBB2,CAV3,CYP27B1,HYAL1,NPR1,PPARD,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SMAD3,SMARCA2,ST20,TP53,TRIM46,TSPYL2,ULK2,WFDC1,WNT5A |
| GO_PROTEIN_AUTOPHOSPHORYLATION | 3.5e-06 | 4.3e-05 | 1652 | 233 | 23 | ABL1,CALM3,CDKL5,EIF2AK4,ENG,EPHA1,ERBB2,FGR,IGF1R,LRRK2,MAP3K11,MAP3K12,MAPK3,NEK10,PDGFC,PDGFD,PRKD1,PTPRC,ROS1,STK16,TNKS1BP1,ULK2,WNK3 |
| GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 3.5e-06 | 4.3e-05 | 1652 | 200 | 21 | ABCD1,ACADL,ADGRF5,APOC3,APOE,ASAH1,BMP5,C3,CYP27B1,DKK3,DKKL1,ELOVL5,GIP,GPAM,GPER1,HTR2C,LPGAT1,PRKCD,REST,STAR,VDR |
| GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY | 3.7e-06 | 4.6e-05 | 1652 | 139 | 17 | AGT,ATP6V0A4,BCAR1,CCND3,EIF4EBP2,FFAR3,IGF1R,MSTN,NCOA5,PIK3R1,PIK3R2,PIK3R3,PRKCD,PTPRA,RARRES2,SLC2A8,ZBTB7B |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 3.7e-06 | 4.6e-05 | 1652 | 1151 | 68 | ACOT2,AGT,ANGPT1,AP2A1,APPL2,ARF3,ARF5,ASPSCR1,BMP4,CACNB3,CD36,COPZ2,DDO,DECR2,DNAJC15,ECI2,ERBB2,ERBIN,FAM53A,GDAP1,HERC2,HSPA1L,ICK,IFT140,KCNIP3,LRRK2,MAVS,MMP12,PDZK1,PEX13,PIK3R1,PIK3R2,PRKCD,PURA,RABL2A,RABL2B,RAMP1,RANBP3L,RASSF9,RBM15B,RTP4,SCP2,SEC16A,SLC27A2,SMAD3,STAT3,STRADA,STX10,STYX,SYTL1,TBC1D2B,TBC1D5,TBC1D9,TMEM129,TOM1L2,TP53,TRIP11,TTC30B,VPS13A,VPS13C,VPS28,VPS37D,VPS39,VPS41,WDR60,ZDHHC12,ZDHHC21,ZIC1 |
| GO_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 3.7e-06 | 4.6e-05 | 1652 | 268 | 25 | ABCA12,ANK2,ANXA13,AR,CACNB3,CAV3,EHD2,FLOT2,GPER1,IKBKB,KCNIP3,LYPD1,PACS1,PIK3R1,PKDCC,PLEKHF1,PPIL2,RAMP1,RAPGEF2,SEC16A,STAC2,TTC7A,VAMP8,VIL1,WNK3 |
| GO_ENDOCRINE_PROCESS | 3.8e-06 | 4.6e-05 | 1652 | 84 | 13 | ACE2,AGT,APLN,CPA3,CTSZ,F2R,F2RL1,GATA3,INHA,MME,OR51E2,RAB11FIP3,SERPINF2 |
| GO_POSITIVE_REGULATION_OF_COLD_INDUCED_THERMOGENESIS | 3.8e-06 | 4.6e-05 | 1652 | 97 | 14 | ACADL,APPL2,CD36,CPT2,ELOVL3,HADH,IGF1R,LEPR,OMA1,PDGFC,PLAC8,THRA,UCP2,ZBTB7B |
| GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 4.0e-06 | 4.9e-05 | 1652 | 252 | 24 | CD4,DLL1,FAM210B,H3-3A,H3C6,HOXA7,INHA,INPP5D,KAT2B,MAFB,MEIS1,MITF,MYL9,NFE2,P4HTM,PIAS3,PIK3R1,PRMT6,PRXL2A,RARG,STAT3,TAL1,TOB2,ZBTB16 |
| GO_STEM_CELL_DIFFERENTIATION | 4.0e-06 | 4.9e-05 | 1652 | 252 | 24 | ABL1,ASCL1,BMP4,CFL1,EDNRA,FBXL17,FOLR1,GATA3,HOXA7,MAPK3,MSI2,OSR1,POU6F2,PTPRC,REST,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SOX5,STAT3,TAL1,TP53,TP63 |
| GO_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 4.2e-06 | 5.0e-05 | 1652 | 435 | 34 | ABCD1,ACADL,AP2A1,APOC3,APOE,APPL2,BAD,BMP5,CNR1,CYP27B1,DKK3,DKKL1,ELOVL5,ENTPD5,GIP,GPAM,GPD1,GPER1,JMJD8,KAT2B,LEPR,LPGAT1,PDP2,PFKFB1,PPP1CB,REST,RORC,SLC7A7,STAR,STAT3,TP53,TTC39B,VDR,ZBTB7A |
| GO_MUSCLE_ORGAN_MORPHOGENESIS | 4.3e-06 | 5.2e-05 | 1652 | 85 | 13 | ADARB1,COL3A1,ENG,FOXH1,MYLK,MYOM1,MYOM3,NOG,RXRA,TGFBR3,TNNC1,TPM1,WNT5A |
| GO_NEGATIVE_REGULATION_OF_TRANSPORT | 4.3e-06 | 5.2e-05 | 1652 | 534 | 39 | ABCA7,ADA,ANGPT1,APOC3,APOE,APPL2,ARL6IP5,ATP1A2,BOK,CACNB3,CALM3,CAV3,CD33,CD36,CNR1,F2R,F2RL1,GPM6B,GSTM2,HADH,HECW2,IL27RA,INHA,JAGN1,KCNE3,KCNE4,LRRK2,NMB,OSR1,PKD2,PKDCC,PNKD,PRKD1,PTPN22,RAB11FIP3,REST,SSC5D,VAMP8,WNK3 |
| GO_PIGMENTATION | 4.3e-06 | 5.2e-05 | 1652 | 98 | 14 | ATRN,BLOC1S1,BLOC1S4,BLOC1S5,EN1,HPS3,HPS6,MC1R,MITF,OR51E2,SHROOM3,SLC24A5,SPARC,VPS33B |
| GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 4.4e-06 | 5.3e-05 | 1652 | 126 | 16 | ABL1,DAND5,DKK1,EID2,MTMR4,NOG,PBLD,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,TGFBR3,TP53,WNT5A,ZBTB7A |
| GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 4.4e-06 | 5.3e-05 | 1652 | 126 | 16 | AGT,ANGPT1,ENTPD5,F2R,F2RL1,FGR,GPER1,IGF1R,MAPK3,PDGFC,PDGFD,PIK3CB,PIK3R1,PIP4K2B,PLXNB1,PPARD |
| GO_RESPONSE_TO_BMP | 4.4e-06 | 5.3e-05 | 1652 | 171 | 19 | ABL1,ADAMTS7,BMP4,DAND5,DKK1,ENG,FBXL15,FKBP8,FSTL1,GATA3,GDF5,HFE,MAPK3,MEGF8,NOG,PCSK6,PDCD4,TGFBR3,WNT5A |
| GO_RESPONSE_TO_INSULIN | 4.5e-06 | 5.4e-05 | 1652 | 271 | 25 | AGT,APPL2,ATP6V0A4,BCAR1,CCND3,EIF4EBP2,FFAR3,HADH,IGF1R,INPPL1,KAT2B,KLF15,LPIN3,MSTN,NCOA5,PFKFB1,PIK3R1,PIK3R2,PIK3R3,PRKCD,PTPRA,RARRES2,SLC2A8,STAR,ZBTB7B |
| GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | 4.5e-06 | 5.3e-05 | 1652 | 112 | 15 | ABCD1,ALOX15B,CYP2C18,CYP2E1,DAGLA,DECR2,ELOVL3,ELOVL5,GSTA1,GSTM2,HPGD,MAPK3,PTGDS,SCP2,TBXAS1 |
| GO_CARDIAC_MUSCLE_CONTRACTION | 4.6e-06 | 5.4e-05 | 1652 | 141 | 17 | ACE2,ANK2,ATP1A2,CALM3,CAV3,CTNNA3,GSTM2,KCNE3,KCNE4,KCNJ3,PPP1R13L,SCN1A,SCN2B,TNNC1,TNNI2,TPM1,VEGFB |
| GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 4.6e-06 | 5.4e-05 | 1652 | 141 | 17 | AXIN2,BMP4,BMP5,COL1A1,DAG1,DLG5,ENG,LOXL3,MCRIP1,NOG,PBLD,PDCD4,PDPN,PHLDB1,SMAD3,TGFBR3,WNT5A |
| GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL | 4.6e-06 | 5.5e-05 | 1652 | 50 | 10 | ACE2,AGT,CPA3,CTSZ,F2R,F2RL1,MME,OR51E2,SERPINF2,TPM1 |
| GO_HORMONE_BIOSYNTHETIC_PROCESS | 4.9e-06 | 5.9e-05 | 1652 | 86 | 13 | BMP5,CHST9,CYP17A1,CYP27B1,DKK3,DKKL1,FFAR3,HFE,HSD17B1,REST,STAR,TRERF1,VDR |
| GO_CARDIAC_SEPTUM_DEVELOPMENT | 5.0e-06 | 5.9e-05 | 1652 | 113 | 15 | ANK2,BMP4,BMP5,DAND5,ENG,GATA3,NDST1,NOG,SEMA3C,STRA6,TAB1,TGFBR3,TP53,TRIP11,WNT5A |
| GO_DRUG_CATABOLIC_PROCESS | 5.0e-06 | 5.9e-05 | 1652 | 142 | 17 | AASS,ADA,ALDH3B1,CTSH,CYP2C18,CYP2E1,CYP4B1,DPYD,DPYS,GPX1,HPD,KYAT1,MAOA,NNT,SULT1A1,SULT1B1,SULT1E1 |
| GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 5.0e-06 | 5.9e-05 | 1652 | 157 | 18 | ABL1,BHLHB9,CDKL5,CUX2,CXCL12,DBNL,DOCK1,EFNA5,LIMS2,MEGF8,OBSL1,PAK3,PLXNB1,PLXNB2,PLXNB3,PLXNC1,RAC3,TRIOBP |
| GO_POSITIVE_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL | 5.0e-06 | 5.9e-05 | 1652 | 40 | 9 | ABL1,CALM3,CAPN3,CASQ1,F2R,GPER1,GSTM2,JPH2,PKD2 |
| GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE | 5.0e-06 | 5.9e-05 | 1652 | 40 | 9 | ACE2,AGT,CPA3,CTSZ,F2R,F2RL1,MME,OR51E2,SERPINF2 |
| GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | 5.2e-06 | 6.1e-05 | 1652 | 173 | 19 | ACE2,ACTA2,ADCY6,AGT,ANGPT1,APLN,APOE,ATP1A2,AZU1,CRP,EDNRA,F2R,F2RL1,GPER1,GPX1,NPR1,PDE3A,PPARD,SERPINF2 |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER | 5.3e-06 | 6.2e-05 | 1652 | 256 | 24 | ADCY6,ADGRG1,ADGRG2,ADGRL3,AGT,CALCR,CNR1,CORT,EDNRA,FFAR3,FPR1,GNA14,GNAI1,GNAQ,GNAT3,GPER1,HTR2C,MC1R,NPR3,PTGER2,RAMP1,RAPGEF2,RXFP1,VIPR1 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 5.3e-06 | 6.3e-05 | 1652 | 831 | 53 | ABCD1,ABL1,ANGEL2,APOC3,APOE,AXIN2,BAD,BOK,BTG2,CAV3,CNR1,CSDC2,DET1,EIF2AK4,ENTPD5,GPD1,GPX1,HFE,KLHL22,LAMTOR1,LEPR,LRRK2,MAPK3,MYD88,NANOS1,NNT,NRBP2,PANO1,PCBP4,PFKFB1,PIK3CB,PIK3R2,PIP4K2B,PLEKHF1,PPP1CB,PRKCD,PRKD1,PTPN22,RNF152,RNF180,SESN1,SOCS5,ST20,STAT3,STYX,TFEB,TP53,TPCN2,TRIM22,ULK2,VPS13C,ZC3H12D,ZYG11B |
| GO_FOREBRAIN_DEVELOPMENT | 5.4e-06 | 6.3e-05 | 1652 | 383 | 31 | ADGRG1,ARPC5,ASCL1,AXL,BAD,BMP4,BTG2,CNTNAP2,COL3A1,CXCL12,DKK1,EPHA5,LAMB1,LHX8,LRRK2,NDST1,NFIB,NOG,NR2F2,PEX13,PLCB1,POU3F3,RAC3,RAPGEF2,RTN4RL1,SUN2,SYNE2,TSKU,VAX2,WNT5A,ZDHHC16 |
| GO_CELL_MATURATION | 5.6e-06 | 6.6e-05 | 1652 | 174 | 19 | ASCL1,AXL,B4GALT6,C3,CDKN1C,CNTNAP2,DEFB1,FAM210B,GATA3,GLDN,LRRK2,NTN4,PDE3A,RAC3,SCARF1,TAL1,TUT4,WASHC5,ZBTB7A |
| GO_GLIOGENESIS | 5.6e-06 | 6.6e-05 | 1652 | 292 | 26 | ABL1,ADGRG1,APCDD1,ASCL1,AZU1,B4GALT6,BOK,CNTNAP1,DAG1,DLL1,ERBB2,GPR183,KLF15,LAMB1,LAMB2,LEPR,MAPK3,MXRA8,NFIB,NLGN3,NOG,STAT3,SUN2,SYNE2,TAL1,TRPC4 |
| GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 5.6e-06 | 6.6e-05 | 1652 | 292 | 26 | ABL1,AGT,ANGPT1,ANGPT2,ANGPT4,APOE,ATOH8,BCAR1,BMP4,CCBE1,CTSH,DOCK1,FGF7,GATA3,HYAL1,MAP2K5,MCC,NR2F2,PBLD,PRKD1,SEMA4A,SERPINF1,SPARC,STARD13,VIL1,WNT5A |
| GO_RESPONSE_TO_VIRUS | 5.6e-06 | 6.5e-05 | 1652 | 328 | 28 | ACTA2,ADARB1,AGBL4,AGBL5,APOBEC3C,APOBEC3G,AZU1,CFL1,CXCL12,EIF2AK4,F2RL1,FGR,GATA3,GPAM,HYAL1,IFITM2,IFITM3,IKBKB,IKBKE,MAVS,MMP12,NLRX1,PARP9,PLSCR1,PPM1B,PTPRC,RTP4,TRIM22 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 5.8e-06 | 6.8e-05 | 1652 | 561 | 40 | ABL1,ADA,ASCL1,AXL,BACE1,BAD,CALM3,CAPN3,CARF,CCR7,CD36,COL18A1,COL1A1,CPNE7,CPOX,CRIP1,CYP2E1,DNMT3A,GIP,GPX1,HFE,KCNMB3,KRT14,LRRK2,MAPK3,MB,PDGFD,PKD2,PLEKHA1,PRKCD,SELENOP,SERPINF1,SPARC,STAR,STIM1,SYT12,TNNC1,TP53,TRPM2,WNT5A |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 5.9e-06 | 6.9e-05 | 1652 | 366 | 30 | ABCD1,APOE,BAD,BTG2,CAV3,DET1,EIF2AK4,ENTPD5,GPD1,LRRK2,MAPK3,NANOS1,NNT,PFKFB1,PIK3CB,PIP4K2B,PLEKHF1,PRKCD,PRKD1,RNF152,RNF180,SESN1,SOCS5,ST20,TFEB,TRIM22,ULK2,VPS13C,ZC3H12D,ZYG11B |
| GO_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | 6.1e-06 | 7.1e-05 | 1652 | 101 | 14 | ABL1,ANK2,ATP1A2,CALCR,CALM3,CAPN3,CASQ1,CD4,F2R,GPER1,GSTM2,JPH2,PKD2,SELENON |
| GO_REGULATION_OF_PROTEIN_BINDING | 6.1e-06 | 7.1e-05 | 1652 | 224 | 22 | ABL1,ANGPT1,APOE,BMP4,CD36,CTSZ,DKK1,EFHB,HFE,LDOC1,LRRK2,MAPK3,NOG,PIN1,PRKCD,RAPGEF2,RIPOR2,SENP2,STYX,TGFBR3,TLE5,WNT5A |
| GO_FATTY_ACYL_COA_METABOLIC_PROCESS | 6.2e-06 | 7.2e-05 | 1652 | 41 | 9 | ABCD1,ACLY,ACSF3,CBR4,ELOVL3,ELOVL5,HACD1,HACD2,SLC25A1 |
| GO_FATTY_ACID_BIOSYNTHETIC_PROCESS | 6.5e-06 | 7.5e-05 | 1652 | 160 | 18 | ABCD1,ACADL,ACLY,ACSF3,ALOX15B,APOC3,CBR4,CYP2E1,DECR2,ELOVL3,ELOVL5,GIP,HACD1,HACD2,HPGD,LPGAT1,PTGDS,TBXAS1 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 6.5e-06 | 7.5e-05 | 1652 | 625 | 43 | ABCA12,ANK2,ANXA13,APOE,AR,ARL13A,BAD,CACNB3,CACNG8,CALM3,CAPN3,CAV3,CPE,DAG1,EHD2,ERBB2,FLOT2,GPER1,HPS6,IKBKB,IQSEC2,KCNIP3,LYPD1,PACS1,PDZK1,PIK3R1,PKDCC,PLEKHF1,PPIL2,RAMP1,RAPGEF2,RTP4,SEC16A,STAC2,TP53,TP63,TTC7A,VAMP8,VIL1,VPS37D,WNK3,ZDHHC12,ZDHHC21 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 6.5e-06 | 7.5e-05 | 1652 | 751 | 49 | ABCD1,ABL1,ACKR3,AJUBA,ARL6IP5,AXIN2,BAD,BOK,CAV3,CCR7,CD36,CREB3L1,CXCL12,DBNL,DKK1,DUSP19,EFHD1,EIF2AK4,ETAA1,EYA1,F2RL1,GPX1,HSPA1L,IGF1R,LANCL1,LRRK2,MAP3K11,MAP3K12,MAPK3,MECOM,NACC2,NUDT16L1,PARP3,PARP9,PDCD4,PHLPP1,PIK3R1,PLCB1,PRKCD,PTPN22,RECQL5,REST,RTN4RL1,SCARF1,SERPINF2,TP53,VPS13C,WNT5A,ZBTB7B |
| GO_CARDIAC_CHAMBER_MORPHOGENESIS | 6.6e-06 | 7.6e-05 | 1652 | 130 | 16 | BMP4,BMP5,CAV3,CPE,ENG,FOXH1,GATA3,NOG,PPP1R13L,RXRA,SEMA3C,TGFBR3,TNNC1,TP53,TPM1,WNT5A |
| GO_CARDIAC_VENTRICLE_DEVELOPMENT | 6.6e-06 | 7.6e-05 | 1652 | 130 | 16 | BMP4,CPE,DAND5,ENG,FOXH1,GATA3,NOG,PPP1R13L,RXRA,SEMA3C,STRA6,TGFBR3,TNNC1,TPM1,TRIP11,WNT5A |
| GO_MUSCLE_ADAPTATION | 6.6e-06 | 7.6e-05 | 1652 | 130 | 16 | AGT,CASQ1,CAV3,DAG1,GTF2IRD1,GTF2IRD2,IGFBP5,KLF15,MLIP,MSTN,MTMR4,PIN1,SELENON,SMAD3,TNNC1,UTRN |
| GO_ORGANOPHOSPHATE_CATABOLIC_PROCESS | 6.6e-06 | 7.6e-05 | 1652 | 130 | 16 | ABCD1,ADA,ENTPD4,GPD1,GPX1,IMPA2,INPP5A,INPP5J,NEIL1,NUDT12,NUDT13,NUDT3,PDE1A,PDE7B,PDE8B,PRKCD |
| GO_PHOSPHATIDYLINOSITOL_PHOSPHORYLATION | 6.7e-06 | 7.7e-05 | 1652 | 52 | 10 | CISH,IMPA2,PIK3CB,PIK3R1,PIK3R2,PIK3R3,PIP4K2B,PIP5KL1,SOCS5,TTC7A |
| GO_PEPTIDYL_TYROSINE_DEPHOSPHORYLATION | 6.9e-06 | 7.9e-05 | 1652 | 102 | 14 | DUSP19,DUSP28,EYA1,HACD2,MDP1,MTMR4,PTPN18,PTPN22,PTPRA,PTPRB,PTPRC,PTPRO,PTPRU,SSH3 |
| GO_FATTY_ACYL_COA_BIOSYNTHETIC_PROCESS | 7.2e-06 | 8.2e-05 | 1652 | 32 | 8 | ACLY,ACSF3,CBR4,ELOVL3,ELOVL5,HACD1,HACD2,SLC25A1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | 7.2e-06 | 8.2e-05 | 1652 | 177 | 19 | ANGPT1,AXL,CALCR,CCR7,ENG,ERBB2,FGF7,GATA3,GPX1,HPSE,IGF1R,IGFBP5,ITSN1,MC1R,PIK3CB,PIK3R1,PIK3R2,STOX1,TNFAIP8L3 |
| GO_DIGESTIVE_SYSTEM_DEVELOPMENT | 7.3e-06 | 8.3e-05 | 1652 | 146 | 17 | ADA,ASCL1,BMP4,CCDC40,CDKN1C,COL3A1,GIP,ITGB4,MEGF8,PDGFC,PKDCC,RARRES2,SLC4A2,SMAD3,STRA6,TP63,WNT5A |
| GO_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 7.3e-06 | 8.3e-05 | 1652 | 89 | 13 | AGT,ANGPT1,F2R,F2RL1,FGR,GPER1,IGF1R,PDGFC,PDGFD,PIK3CB,PIK3R1,PLXNB1,PPARD |
| GO_PROTEOGLYCAN_METABOLIC_PROCESS | 7.3e-06 | 8.3e-05 | 1652 | 89 | 13 | BGN,CHST14,CHST9,EXT2,HPSE,HS3ST3B1,HS6ST3,HYAL1,NDST1,NDST4,PPARD,SGSH,SLC35D1 |
| GO_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION | 7.8e-06 | 8.8e-05 | 1652 | 16 | 6 | AGT,CASQ1,DAG1,MTMR4,SELENON,UTRN |
| GO_SKELETAL_MUSCLE_CELL_PROLIFERATION | 7.8e-06 | 8.8e-05 | 1652 | 16 | 6 | ANGPT1,MSTN,PPARD,SELENON,SIX5,STAT3 |
| GO_REGULATION_OF_CELL_SIZE | 8.5e-06 | 9.6e-05 | 1652 | 179 | 19 | ABL1,APOE,CAV3,CDKL5,CXCL12,DBNL,EFNA5,KCNN4,MEGF8,PRR16,RARG,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SLC12A9,TRIM46,ULK2,WNT5A |
| GO_ANIMAL_ORGAN_FORMATION | 8.6e-06 | 9.7e-05 | 1652 | 65 | 11 | AR,AXIN2,BMP4,DKK1,EYA1,FOLR1,FOXH1,MAPK3,NOG,TP63,WNT5A |
| GO_PROSTATIC_BUD_FORMATION | 8.6e-06 | 9.7e-05 | 1652 | 10 | 5 | AR,BMP4,NOG,TP63,WNT5A |
| GO_RESPIRATORY_GASEOUS_EXCHANGE_BY_RESPIRATORY_SYSTEM | 8.6e-06 | 9.7e-05 | 1652 | 65 | 11 | APLN,ATP1A2,CCBE1,DACH1,EDNRA,MAFB,NDST1,NLGN3,SELENON,SLC5A3,TNNC1 |
| GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | 8.7e-06 | 9.7e-05 | 1652 | 104 | 14 | ABL1,BCAR1,COL3A1,DOCK1,ERBIN,FGR,ITGA11,ITGB4,ITGB8,LAMA3,LIMS2,LOXL3,PRKD1,TLN1 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 8.7e-06 | 9.7e-05 | 1652 | 104 | 14 | ABCD1,ADA,ENTPD4,GPX1,NEIL1,NME3,NME4,NUDT12,NUDT13,NUDT3,PDE1A,PDE7B,PDE8B,TK2 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 8.8e-06 | 9.9e-05 | 1652 | 912 | 56 | ABL1,ANAPC11,ANAPC13,ANAPC16,ANGPT1,AREL1,ASB13,ASB9,BCOR,CAPN3,CISH,CUL9,DCAF8,DET1,EYA1,FBXL15,FBXL17,FBXL19,FBXL22,FBXO41,FBXO9,HECW2,HERC2,KLHL10,KLHL22,KLHL3,KLHL36,KLHL41,LNPEP,LRRK2,LZTR1,MGRN1,NEDD8,PEX13,PIAS3,PIN1,PPIL2,PRR7,PTPN22,RNF150,RNF152,RNF180,RNF208,RNF213,SENP2,SOCS5,TMEM129,TRIM22,TRIM37,TRIM69,TRIM7,UBA7,UBE3B,USP22,VPS28,ZBTB16 |
| GO_ACTION_POTENTIAL | 8.9e-06 | 9.9e-05 | 1652 | 133 | 16 | ANK2,ATP1A2,CACNB3,CAV3,CD36,CNR1,CNTNAP1,CTNNA3,GNAQ,GPER1,KCNE3,KCNE4,KCNJ3,KCNMB3,SCN1A,SCN2B |
| GO_REGULATION_OF_EMBRYONIC_DEVELOPMENT | 8.9e-06 | 9.9e-05 | 1652 | 133 | 16 | AR,BMP4,CELSR1,COL5A2,DAG1,DKK1,DLL1,GATA3,LAMA3,MAP2K5,OSR1,PHLDB1,PLCB1,STOX1,TBX18,WNT5A |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 9.0e-06 | 1.0e-04 | 1652 | 1114 | 65 | ABL1,ANAPC11,ANAPC13,ANAPC16,ANGPT1,AR,AREL1,ASB13,ASB9,BCOR,CAPN3,CISH,CUL9,DCAF8,DET1,EYA1,FBXL15,FBXL17,FBXL19,FBXL22,FBXO41,FBXO9,GATA3,HECW2,HERC2,KAT2B,KLHL10,KLHL22,KLHL3,KLHL36,KLHL41,LNPEP,LRRK2,LZTR1,MGRN1,MINDY1,NEDD8,PEX13,PIAS3,PIN1,PPIL2,PRR7,PTPN22,RNF150,RNF152,RNF180,RNF208,RNF213,SENP2,SMAD3,SOCS5,TAB1,TMEM129,TP53,TRIM22,TRIM37,TRIM69,TRIM7,UBA7,UBE3B,USP22,USP54,VPS28,ZBTB16,ZRANB1 |
| GO_TUBE_FORMATION | 9.6e-06 | 1.1e-04 | 1652 | 149 | 17 | ABL1,ATOH8,BMP4,BMP5,CELSR1,CFL1,FOLR1,FZD6,GATA3,IRX3,NFIB,NOG,OSR1,PLXNB2,RARG,SHROOM3,WNT5A |
| GO_MESODERM_DEVELOPMENT | 9.7e-06 | 1.1e-04 | 1652 | 134 | 16 | BMP4,DAND5,DKK1,EXT2,EYA1,FOXH1,IRX3,ITGB4,NOG,OSR1,SECTM1,SMAD3,TAL1,TIE1,TP63,WNT5A |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 9.7e-06 | 1.1e-04 | 1652 | 134 | 16 | CLDN7,DKK1,DNAJC15,FHOD3,INPP5J,LMOD1,PMEPA1,PRKCD,RAF1,SPTBN2,THRA,TMOD1,TMSB15B,TRIOBP,VIL1,VILL |
| GO_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORT | 9.7e-06 | 1.1e-04 | 1652 | 134 | 16 | ABCD1,AGT,ARL6IP5,ATP1A2,CPT2,EMB,FOLR1,PDPN,SLC13A4,SLC16A7,SLC1A1,SLC25A1,SLC35D1,SLC38A10,SLC7A7,STRA6 |
| GO_GLYCOLIPID_BIOSYNTHETIC_PROCESS | 1.0e-05 | 1.1e-04 | 1652 | 66 | 11 | B3GALT4,B4GALT6,DPM3,MPPE1,PIGB,PIGQ,PIGS,PIGT,ST3GAL6,ST6GALNAC5,ST6GALNAC6 |
| GO_GLYCOSPHINGOLIPID_METABOLIC_PROCESS | 1.0e-05 | 1.1e-04 | 1652 | 66 | 11 | ARSA,ASAH1,B3GALT4,B4GALT6,CERK,ITGB8,PRKCD,ST6GALNAC5,ST6GALNAC6,STS,SUMF1 |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | 1.0e-05 | 1.1e-04 | 1652 | 266 | 24 | ABCA7,AGT,ANGPT1,APPL2,BMP4,CD36,COL1A1,FAM53A,LRRK2,MAVS,MMP12,PARP9,PIK3R1,PIK3R2,PIN1,PRKCD,SMAD3,STAT3,SUN2,TP53,TRIM29,ZBTB16,ZBTB7A,ZIC1 |
| GO_REGULATION_OF_LIPID_KINASE_ACTIVITY | 1.0e-05 | 1.1e-04 | 1652 | 66 | 11 | CCR7,CISH,FGR,PIK3R1,PIK3R2,PIK3R3,PRKD1,RBL2,SOCS5,TNFAIP8L3,WDR81 |
| GO_CELL_CYCLE_PROCESS | 1.1e-05 | 1.2e-04 | 1652 | 1399 | 77 | ABL1,ACTR1B,AJUBA,ANAPC11,ANAPC16,APBB2,AXIN2,BMP4,BRINP3,BTG2,CALM3,CAPN3,CCDC69,CCND3,CDKN1C,CDKN2B,CEP70,CFL1,CHMP6,CNOT11,CUL9,CXCR5,CYP27B1,DACH1,EIF2AK4,FBXL15,FBXL22,GAS1,GNAI1,GPER1,HECW2,HYAL1,INHA,INTS3,KANK2,KAT14,KAT2B,KDM8,KLHL22,LAMTOR1,MDC1,NACC2,NEK10,NINL,OBSL1,PARP3,PCBP4,PDE3A,PIN1,PKD2,PKHD1,PLCB1,POGZ,PPP1CB,PTPA,PTPRC,RAB11FIP3,RBL2,RECQL5,REEP3,RTKN,SENP2,SEPTIN11,SEPTIN8,SLC2A8,SMAD3,STOX1,STRADA,SUN2,TDRD9,TNKS1BP1,TOM1L2,TP53,TRIM37,UBXN2B,WASHC5,WNT5A |
| GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 1.1e-05 | 1.2e-04 | 1652 | 215 | 21 | AGT,APPL2,ATP6V0A4,BCAR1,CCND3,EIF4EBP2,FFAR3,IGF1R,KAT2B,LPIN3,MSTN,NCOA5,PIK3R1,PIK3R2,PIK3R3,PRKCD,PTPRA,RARRES2,SLC2A8,STAR,ZBTB7B |
| GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 1.1e-05 | 1.3e-04 | 1652 | 233 | 22 | ABL1,APOE,BMP4,CDKL5,CXCL12,DBNL,EFNA5,EIF2AK4,FLRT3,FMN1,LAMB2,MEGF8,NLGN3,RARG,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPG11,TRIM46,ULK2,WNT5A |
| GO_INORGANIC_ANION_TRANSPORT | 1.1e-05 | 1.2e-04 | 1652 | 166 | 18 | ANO2,ANO8,APOL1,BEST2,BEST4,CLCA2,CLCNKA,CLIC3,FXYD3,ROS1,SLC12A9,SLC13A4,SLC1A1,SLC20A2,SLC26A1,SLC26A2,SLC37A2,SLC4A2 |
| GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 1.1e-05 | 1.2e-04 | 1652 | 455 | 34 | ANGPT1,APOBEC3G,APPL2,C1R,C3,C4A,C4B,CADM1,CD36,CFB,CR1,CUEDC2,EIF2AK4,F2RL1,FFAR3,FGR,GATA3,HFE,IL1R1,IL27RA,LOXL3,MAPK3,MAVS,MMP12,MYO18A,NLRX1,PARP3,PARP9,PPM1B,PTPRC,SOCS5,VAMP8,WNT5A,ZBTB7B |
| GO_AGING | 1.2e-05 | 1.3e-04 | 1652 | 323 | 27 | ABL1,ADA,AGT,ALDH3A1,CDKN1C,CDKN2B,CNR1,DAG1,DKK1,DNMT3A,ENG,ENO3,IGFBP5,INPP5D,KMO,KRT14,LRRK2,MAPK3,MME,MMP7,PDCD4,PRKCD,PRMT6,SERPINF1,STAT3,TP53,TP63 |
| GO_FORMATION_OF_PRIMARY_GERM_LAYER | 1.2e-05 | 1.3e-04 | 1652 | 121 | 15 | ATOH8,BMP4,COL12A1,COL5A2,DKK1,EXT2,EYA1,ITGB4,LAMA3,LAMB1,MMP2,NOG,SMAD3,TAL1,WNT5A |
| GO_GLANDULAR_EPITHELIAL_CELL_DEVELOPMENT | 1.2e-05 | 1.3e-04 | 1652 | 25 | 7 | BAD,BMP4,BMP5,DLL1,RARG,SIDT2,WNT5A |
| GO_LINOLEIC_ACID_METABOLIC_PROCESS | 1.2e-05 | 1.3e-04 | 1652 | 17 | 6 | ABCD1,ALOX15B,ELOVL3,ELOVL5,GSTA1,GSTM2 |
| GO_MONOCARBOXYLIC_ACID_TRANSPORT | 1.2e-05 | 1.3e-04 | 1652 | 167 | 18 | ABCC3,ABCD1,APOE,CD36,CPT2,EMB,NMB,PPARD,RXRA,SLC16A14,SLC16A7,SLC27A2,SLC27A4,SLCO1B1,SLCO2A1,STRA6,SV2A,TRPC4 |
| GO_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD | 1.2e-05 | 1.3e-04 | 1652 | 25 | 7 | AR,BMP4,BMP5,CFL1,NOG,TP63,WNT5A |
| GO_REGULATION_OF_GTPASE_ACTIVITY | 1.2e-05 | 1.3e-04 | 1652 | 477 | 35 | AGFG2,AJUBA,CCR7,CDKL5,CHN1,DOCK1,DOCK11,EFNA5,EPHA1,EPHA5,ERBB2,F2R,F2RL1,FGD3,FGD4,GNAQ,LRRK2,MTSS2,PIN1,PLCB1,PLEKHG6,PLXNB1,PLXNB2,PLXNB3,PLXNC1,RANBP3L,RAPGEF2,RIN2,RTKN,STARD13,TAX1BP3,TBC1D2B,TBC1D5,TBC1D9,WNT5A |
| GO_REGULATION_OF_MUSCLE_ADAPTATION | 1.2e-05 | 1.3e-04 | 1652 | 107 | 14 | AGT,CASQ1,CAV3,DAG1,GTF2IRD1,GTF2IRD2,IGFBP5,MLIP,MTMR4,PIN1,SELENON,SMAD3,TNNC1,UTRN |
| GO_CILIUM_ORGANIZATION | 1.3e-05 | 1.4e-04 | 1652 | 381 | 30 | ARL13A,ARMC4,BBOF1,CCDC151,CCDC28B,CCDC40,CDKL5,CELSR3,CEP70,ICK,IFT140,MAFIP,NINL,NPHP1,NUDCD3,PKD2,PKHD1,RABL2B,SEPTIN11,SPAG16,STK36,SYNE2,TBC1D32,TCTN3,TMEM107,TMEM80,TRIP11,TTC30B,TTC39C,WDR60 |
| GO_NEURON_PROJECTION_EXTENSION | 1.3e-05 | 1.4e-04 | 1652 | 168 | 18 | ABL1,APOE,CDKL5,CXCL12,DBNL,EIF2AK4,FLRT3,LAMB2,MEGF8,NLGN3,SEMA3B,SEMA3C,SEMA3E,SEMA4A,SPG11,TRIM46,ULK2,WNT5A |
| GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 1.3e-05 | 1.4e-04 | 1652 | 184 | 19 | ABL1,AJUBA,APOL3,CCR7,CD36,CD4,CXXC5,F2R,F2RL1,IKBKB,IKBKE,JMJD8,MAVS,MYD88,PLEKHG5,PRKD1,SECTM1,TMEM9B,TRIM22 |
| GO_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 1.3e-05 | 1.4e-04 | 1652 | 201 | 20 | ABL1,ACTR3B,APOE,ARPC5,ARPIN,CAV3,CCR7,CFL1,EPHA1,F2RL1,FHOD1,FMN1,GMFB,GPX1,LMOD1,SERPINF2,SMAD3,SYNPO,TPM1,VIL1 |
| GO_REGULATION_OF_DENDRITE_DEVELOPMENT | 1.3e-05 | 1.4e-04 | 1652 | 152 | 17 | APOE,BHLHB9,BMP5,CDKL5,CFL1,CSMD3,CUX2,DBNL,DLG5,HECW2,ITSN1,LRRK2,NLGN3,NSMF,OBSL1,PAK3,RAPGEF2 |
| GO_CELL_FATE_COMMITMENT | 1.4e-05 | 1.5e-04 | 1652 | 271 | 24 | AR,ASCL1,BMP4,DKK1,DLL1,EYA1,FKBP8,GAS1,GATA3,GLIS1,LOXL3,MITF,NR2F2,PDPN,POU6F2,RORC,SOX12,SOX5,STAT3,TAL1,TBX18,TP53,WNT5A,ZBTB7B |
| GO_MALE_GAMETE_GENERATION | 1.4e-05 | 1.5e-04 | 1652 | 562 | 39 | ADAMTS2,ADGRG2,AR,ARID4A,ATP1A4,AXL,BAD,C9orf24,CADM1,CCDC87,CNR1,DEFB1,DNMT3A,H3-3A,HERC2,KLHL10,LIMK2,LRRK2,NPHP1,PLEKHA1,PYGO2,ROS1,SERPINA5,SIX5,SLC2A14,SLC2A8,SLC4A2,SMARCA2,SPAG16,SPATA20,SPATA25,TDRD9,TMEM203,TP63,TSNAXIP1,TSPAN8,VCX,ZBTB16,ZNF541 |
| GO_PEROXISOME_ORGANIZATION | 1.4e-05 | 1.5e-04 | 1652 | 81 | 12 | ABCD1,ACOT2,DDO,DECR2,ECI2,MAVS,PEX11A,PEX11B,PEX11G,PEX13,SCP2,SLC27A2 |
| GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL | 1.4e-05 | 1.5e-04 | 1652 | 81 | 12 | ABL1,ANK2,ATP1A2,CALM3,CAPN3,CASQ1,F2R,GPER1,GSTM2,JPH2,PKD2,SELENON |
| GO_ADAPTIVE_THERMOGENESIS | 1.5e-05 | 1.6e-04 | 1652 | 154 | 17 | ACADL,ACOT11,APPL2,CD36,CPT2,ELOVL3,HADH,IGF1R,LEPR,LNPEP,NPR3,OMA1,PDGFC,PLAC8,THRA,UCP2,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 1.5e-05 | 1.6e-04 | 1652 | 35 | 8 | BCOR,BMP4,GATA3,LIMS2,NFIB,NOG,RSPO2,WNT5A |
| GO_NEGATIVE_REGULATION_OF_HORMONE_METABOLIC_PROCESS | 1.5e-05 | 1.6e-04 | 1652 | 11 | 5 | BMP5,CYP27B1,DKK3,DKKL1,REST |
| GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | 1.5e-05 | 1.6e-04 | 1652 | 186 | 19 | ABL1,APOE,BMP4,CAV3,DAG1,DUSP19,F2RL1,FBLN1,GPER1,IGF1R,LAX1,MECOM,PDCD4,PIK3R2,PIN1,PRKCD,PSCA,PTPN22,PTPRC |
| GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 1.5e-05 | 1.6e-04 | 1652 | 237 | 22 | ABL1,ADGRG1,APOC3,APOE,ARHGEF17,ARHGEF25,COL3A1,F2R,F2RL1,FGD3,FGD4,IQSEC2,ITSN1,KANK2,LPAR6,LZTR1,PLCE1,PLEKHG5,PLEKHG6,RAF1,RIPOR2,TRIO |
| GO_LIPID_HOMEOSTASIS | 1.6e-05 | 1.7e-04 | 1652 | 155 | 17 | ABCA12,ABCD1,ABHD4,APOC3,APOE,CAV3,CETP,CYP7B1,GIP,GPAM,LAMTOR1,LIMA1,MTTP,PNPLA3,TTC39B,USF2,VDR |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | 1.6e-05 | 1.7e-04 | 1652 | 82 | 12 | DAND5,EID2,MTMR4,PBLD,PIN1,PMEPA1,RASL11B,SMAD3,SNX25,TGFBR3,TP53,ZBTB7A |
| GO_PHARYNGEAL_SYSTEM_DEVELOPMENT | 1.6e-05 | 1.7e-04 | 1652 | 26 | 7 | ADGRF5,BMP4,BMP5,EYA1,FOLR1,GATA3,NOG |
| GO_PROTEIN_POLYMERIZATION | 1.6e-05 | 1.6e-04 | 1652 | 273 | 24 | ABL1,ACTR3B,ARPC5,ARPIN,CASQ1,CAV3,CCR7,CORO7,DBNL,FHOD3,FMN1,GMFB,INPP5J,LMOD1,MSRB1,MSRB2,PAK3,PRKCD,SPTBN2,TMOD1,TMSB15B,TRIOBP,VIL1,VILL |
| GO_STEROID_CATABOLIC_PROCESS | 1.6e-05 | 1.7e-04 | 1652 | 26 | 7 | APOE,CEL,CYP27B1,SCARF1,STS,SULT1E1,TRERF1 |
| GO_VIRAL_LIFE_CYCLE | 1.6e-05 | 1.7e-04 | 1652 | 328 | 27 | ACE2,ADARB1,ANPEP,APOBEC3C,APOBEC3G,APOE,AXL,CD4,CHMP6,CR1,DAG1,DPP4,EEA1,EIF2AK4,HAVCR1,HYAL1,IFITM2,IFITM3,MAVS,NFIA,PLSCR1,SLC20A2,SLC52A1,TASOR,VAMP8,VPS28,VPS37D |
| GO_CELL_CELL_JUNCTION_ORGANIZATION | 1.7e-05 | 1.8e-04 | 1652 | 188 | 19 | ACE2,ACTN4,AGT,ANK2,CADM1,CADM3,CDH6,CNTNAP1,DLG5,F2R,F2RL1,FSCN1,IKBKB,LIMS2,NPHP1,PLEKHA7,PTPRO,SMAD3,TLN1 |
| GO_DIRECT_OSSIFICATION | 1.7e-05 | 1.8e-04 | 1652 | 6 | 4 | AXIN2,COL1A1,MMP2,MN1 |
| GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 1.7e-05 | 1.8e-04 | 1652 | 96 | 13 | ACTN4,EFNA5,FBLN1,NLGN3,PTPRO,RAPGEF2,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,ULK2,WNT5A |
| GO_POSITIVE_REGULATION_OF_NEURON_DEATH | 1.7e-05 | 1.8e-04 | 1652 | 96 | 13 | ABL1,ASCL1,BACE1,BAD,CTSZ,DKK1,KMO,MAP3K11,PAK3,PIN1,REST,TP53,WNT5A |
| GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH | 1.7e-05 | 1.7e-04 | 1652 | 110 | 14 | ABL1,APOE,CDKL5,CXCL12,DBNL,EFNA5,MEGF8,SEMA3B,SEMA3C,SEMA3E,SEMA4A,TRIM46,ULK2,WNT5A |
| GO_REGULATION_OF_INFLAMMATORY_RESPONSE | 1.7e-05 | 1.8e-04 | 1652 | 387 | 30 | ABCD1,ACE2,ADA,AGT,APOE,APPL2,C3,CCR7,CNR1,CUEDC2,FFAR3,GATA3,GPER1,GPX1,IL17RC,IL1R1,LRRK2,MGST2,MYD88,NLRX1,PDCD4,PPARD,PRKCD,PTPRC,SERPINF1,SMAD3,SOCS5,VAMP8,WFDC1,WNT5A |
| GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | 1.7e-05 | 1.8e-04 | 1652 | 140 | 16 | APLN,ARL6IP5,ATP1A2,BACE1,CALM3,CNR1,GPER1,GPM6B,HTR2C,KMO,LRRK2,PNKD,SNCAIP,SV2A,SYT12,VAMP8 |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 1.8e-05 | 1.8e-04 | 1652 | 547 | 38 | BLCAP,BMP1,BOK,C3,CFL1,CTSS,DKK1,DPP4,F2RL1,FSCN1,FUNDC1,GPER1,IGF1R,LIMA1,LMOD1,MAP1LC3C,MMP12,MMP2,MMP7,MRPL41,NFE2,PADI2,PBRM1,PDPN,PYM1,SMARCD2,SPTBN2,ST20,TECPR1,TEX264,TLL1,TMOD1,TP53,TRIOBP,VAMP8,VIL1,VILL,VPS13C |
| GO_CELLULAR_RESPONSE_TO_PEPTIDE | 1.8e-05 | 1.9e-04 | 1652 | 388 | 30 | ADCY6,AGT,APPL2,ATP6V0A4,BACE1,BCAR1,CCND3,CD36,EIF4EBP2,FFAR3,GPER1,IGF1R,KAT2B,KLF15,LDOC1,LPIN3,MSTN,NCOA5,PIK3R1,PIK3R2,PIK3R3,PRKCD,PTPN22,PTPRA,RARRES2,SLC2A8,STAR,STAT3,TP53,ZBTB7B |
| GO_ENDOTHELIAL_CELL_MIGRATION | 1.8e-05 | 1.8e-04 | 1652 | 275 | 24 | ABL1,AGT,ANGPT1,ANGPT2,ANGPT4,APOE,ATOH8,BCAR1,BMP4,CCBE1,DPP4,GATA3,GPX1,MAP2K5,NR2F2,PIK3R3,PLEKHG5,PRKD1,SEMA4A,SERPINF1,SPARC,STARD13,TNFSF12,WNT5A |
| GO_HINDLIMB_MORPHOGENESIS | 1.8e-05 | 1.9e-04 | 1652 | 36 | 8 | BMP4,FMN1,GDF5,OSR1,RARG,RSPO2,TP63,ZBTB16 |
| GO_INTERLEUKIN_8_PRODUCTION | 1.8e-05 | 1.9e-04 | 1652 | 83 | 12 | CD33,CRP,F2R,F2RL1,MAP2K5,MAVS,MYD88,PTPN22,PTPRC,SSC5D,TLR1,WNT5A |
| GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS | 1.8e-05 | 1.8e-04 | 1652 | 70 | 11 | ABCD1,ADA,ENTPD4,GPX1,NEIL1,NUDT12,NUDT13,NUDT3,PDE1A,PDE7B,PDE8B |
| GO_POSITIVE_CHEMOTAXIS | 1.8e-05 | 1.8e-04 | 1652 | 70 | 11 | ANGPT1,ANGPT2,AZU1,BMP4,CXCL12,F2RL1,FGF7,PLXNB3,SMAD3,VEGFB,WNT5A |
| GO_REGULATION_OF_MUSCLE_CONTRACTION | 1.8e-05 | 1.8e-04 | 1652 | 172 | 18 | ACE2,ADA,ANK2,ATP1A2,CALM3,CASQ1,CAV3,CTNNA3,DMPK,F2R,GPER1,GSTM2,KCNE3,MYL9,PLCE1,TNNC1,TNNI2,TPM1 |
| GO_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | 1.8e-05 | 1.9e-04 | 1652 | 111 | 14 | ABL1,AGT,AOC3,APOE,CALM3,CAV3,CNR1,CYGB,CYP27B1,LRRK2,NPR3,PDP2,VDR,ZDHHC21 |
| GO_AMMONIUM_ION_METABOLIC_PROCESS | 1.9e-05 | 1.9e-04 | 1652 | 206 | 20 | ABHD4,ACADL,ALDH9A1,ASAH1,CBR4,CETP,DBI,LPIN3,MAOA,NPR1,PLAAT2,PLAAT4,PLB1,PNKD,PRKCD,RNF180,SARDH,SGPP2,SHMT1,SNCAIP |
| GO_INNATE_IMMUNE_RESPONSE | 1.9e-05 | 2.0e-04 | 1652 | 1005 | 59 | ADARB1,APOBEC3C,APOBEC3G,APOE,APOL1,APPL2,AXL,C1R,C1RL,C3,C4A,C4B,CADM1,CD36,CFB,CR1,CRISP3,CRP,CTSS,CYBC1,CYP27B1,DEFB1,ERBIN,F2RL1,FBXO9,FGR,GATA3,GPER1,HEXIM1,IFITM2,IFITM3,IGHV3-73,IKBKB,IKBKE,JCHAIN,MAVS,MMP12,MR1,MSRB1,MUC15,MYD88,NLRX1,PAK3,PARP9,PLSCR1,PRKCD,PRKD1,PTPN22,RAF1,RARRES2,SSC5D,STAR,TAB1,TLR1,TP53,TRIM22,TRIM29,TRIM59,WNT5A |
| GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS | 1.9e-05 | 2.0e-04 | 1652 | 157 | 17 | BMP4,CTLA4,DLL1,ERBB2,HOXA7,INHA,INPP5D,LOXL3,MAFB,MEIS1,PIAS3,PIK3R1,SOCS5,TAL1,TOB2,ZBTB16,ZBTB7B |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION | 1.9e-05 | 1.9e-04 | 1652 | 141 | 16 | ABL1,ALOX15B,CADM1,F2R,F2RL1,FGR,GATA3,IL17RC,LRRK2,MAPK3,MAVS,MMP12,ORM1,PTPN22,TLR1,WNT5A |
| GO_REGULATION_OF_STEROID_METABOLIC_PROCESS | 1.9e-05 | 1.9e-04 | 1652 | 126 | 15 | ACADL,AGT,APOE,ASAH1,BMP5,CYP27B1,DKK3,DKKL1,GPAM,LAMTOR1,REST,RORC,STAR,TTC39B,VDR |
| GO_BONE_MINERALIZATION | 2.0e-05 | 2.1e-04 | 1652 | 112 | 14 | AXIN2,BCOR,BMP4,CLEC3B,COL1A2,CYP27B1,FBXL15,FGR,GPM6B,MGP,OSR1,PKDCC,RSPO2,SMAD3 |
| GO_COLLAGEN_CATABOLIC_PROCESS | 2.0e-05 | 2.0e-04 | 1652 | 47 | 9 | ADAMTS2,COL15A1,CTSS,MMP12,MMP2,MMP25,MMP28,MMP7,MRC2 |
| GO_SARCOMERE_ORGANIZATION | 2.0e-05 | 2.0e-04 | 1652 | 47 | 9 | CAPN3,CASQ1,CAV3,FHOD3,KLHL41,LDB3,MYOM1,MYOM3,TPM1 |
| GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT | 2.1e-05 | 2.1e-04 | 1652 | 127 | 15 | BMP4,COL1A1,EYA1,HOXA4,HOXA7,HYAL1,IFT140,MEGF8,NDST1,NOG,OSR1,SLC35D1,SMAD3,WDR60,WNT5A |
| GO_HORMONE_TRANSPORT | 2.1e-05 | 2.2e-04 | 1652 | 315 | 26 | AGT,APLN,BAD,CNR1,CPE,DPP4,EFNA5,EPHA5,FFAR3,GATA3,GIP,GPER1,HADH,HFE,HMGN3,HTR2C,INHA,ITSN1,JAGN1,NMB,PPARD,RAB11FIP3,RAF1,REST,SIDT2,VAMP8 |
| GO_MITOTIC_CELL_CYCLE | 2.1e-05 | 2.1e-04 | 1652 | 1030 | 60 | ABL1,ACTR1B,AJUBA,ANAPC11,ANAPC16,ANGEL2,ASCL1,BMP4,BRINP3,BTG2,CALM3,CCND3,CDKN1C,CDKN2B,CEP70,CFL1,CHMP6,CNOT11,CUL9,DNMT3A,FBXL15,FBXL22,GAS1,GNAI1,HECW2,HYAL1,INTS3,KANK2,KAT14,KDM8,KLHL22,MDC1,NACC2,NINL,OBSL1,PARP3,PBRM1,PCBP4,PIN1,PKD2,PLCB1,POGZ,PPP1CB,PTPA,RBL2,RECQL5,REEP3,RTKN,SENP2,SMAD3,STOX1,SUN2,TAL1,TNKS1BP1,TOM1L2,TP53,TTC28,TUBA3E,UBXN2B,USP22 |
| GO_REGULATION_OF_HORMONE_SECRETION | 2.1e-05 | 2.1e-04 | 1652 | 260 | 23 | AGT,APLN,BAD,CNR1,DPP4,EFNA5,EPHA5,FFAR3,GIP,GPER1,HADH,HFE,HMGN3,HTR2C,INHA,ITSN1,JAGN1,NMB,PPARD,RAB11FIP3,REST,SIDT2,VAMP8 |
| GO_ERBB_SIGNALING_PATHWAY | 2.2e-05 | 2.2e-04 | 1652 | 143 | 16 | ABL1,AGT,BCAR1,CHMP6,DOK1,EFEMP1,ERBB2,ERBIN,GPER1,GRB7,PDE6G,PIK3R1,PLCE1,PTPN18,SOCS5,VIL1 |
| GO_REGULATION_OF_TUBE_SIZE | 2.2e-05 | 2.2e-04 | 1652 | 143 | 16 | ACE2,ACTA2,ADCY6,AGT,APLN,APOE,ATP1A2,CRP,EDNRA,F2R,F2RL1,GPER1,GPX1,NPR1,PPARD,SERPINF2 |
| GO_PROTEIN_IMPORT | 2.3e-05 | 2.3e-04 | 1652 | 192 | 19 | AGT,ANGPT1,APOE,APPL2,BMP4,CD36,DNAJC15,FAM53A,LRRK2,MAVS,MMP12,PEX13,PIK3R1,PIK3R2,PRKCD,SMAD3,STAT3,TP53,ZIC1 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 2.4e-05 | 2.4e-04 | 1652 | 1036 | 60 | ABL1,ACTR3B,ANGPT1,ANGPT4,ARMC4,ARPC5,ARPIN,C9orf24,CABIN1,CADPS2,CASQ1,CAV3,CCDC151,CCDC40,CCR7,CD36,COA5,CORO7,DBNL,DMAC1,EFNA5,EID2,ERCC5,FHOD3,FMN1,GMFB,GTF2H5,H3-3A,H3C6,HOPX,INPP5J,LMOD1,MSRB1,MSRB2,MYOM1,MYOM3,NDUFV2,NUBPL,PAK3,PDGFC,PMEPA1,POGZ,PRKCD,SEPTIN8,SMAD3,SOX12,SPTBN2,SV2A,TGFBR3,THRA,TMOD1,TMSB15B,TP53,TRIOBP,TSPYL2,TSPYL4,UNC13C,VIL1,VILL,VPS41 |
| GO_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS | 2.4e-05 | 2.4e-04 | 1652 | 99 | 13 | ACLY,ACSF3,BDH2,CBR4,ELOVL3,ELOVL5,HACD1,HACD2,HPGD,MGST2,PTGDS,SLC25A1,TBXAS1 |
| GO_NEURON_MATURATION | 2.4e-05 | 2.4e-04 | 1652 | 48 | 9 | B4GALT6,C3,CDKN1C,CNTNAP2,GLDN,LRRK2,NTN4,RAC3,SCARF1 |
| GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | 2.4e-05 | 2.4e-04 | 1652 | 99 | 13 | ADA,CALM3,CD4,EFHB,GSTM2,JPH2,LRRK2,PKD2,RCAN1,RCAN3,SELENON,STIMATE,TMBIM4 |
| GO_TRABECULA_MORPHOGENESIS | 2.4e-05 | 2.4e-04 | 1652 | 48 | 9 | BMP5,CAV3,COL1A1,ENG,FOXH1,MMP2,NOG,PLXNB1,TGFBR3 |
| GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | 2.5e-05 | 2.5e-04 | 1652 | 114 | 14 | ANGPT1,AP2A1,B4GALT1,B4GALT6,BGN,CHST14,CHST9,HYAL1,ITIH3,NDST1,NDST4,SLC35D1,ST3GAL3,ST3GAL6 |
| GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 2.5e-05 | 2.5e-04 | 1652 | 337 | 27 | ABL1,ADGRG1,APOC3,APOE,ARHGEF17,ARHGEF25,CHN1,COL3A1,F2R,F2RL1,FGD3,FGD4,IQSEC2,ITSN1,KANK2,LPAR6,LZTR1,PIK3R2,PLCE1,PLEKHG5,PLEKHG6,RAC3,RAF1,RHOBTB2,RIPOR2,STARD13,TRIO |
| GO_INNER_EAR_MORPHOGENESIS | 2.6e-05 | 2.6e-04 | 1652 | 100 | 13 | CELSR1,EYA1,FZD6,GATA3,MAFB,POU3F4,RIPOR2,SLITRK6,STOX1,TRIOBP,TTC39C,WNT5A,ZIC1 |
| GO_MYOBLAST_DIFFERENTIATION | 2.6e-05 | 2.6e-04 | 1652 | 86 | 12 | ANKRD2,BMP4,CAPN3,DLL1,FLOT2,KLHL41,MSTN,PLCB1,PPARD,RANBP3L,REST,RIPOR2 |
| GO_NEGATIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 2.6e-05 | 2.5e-04 | 1652 | 12 | 5 | DKK1,NOG,PBLD,PMEPA1,SNX25 |
| GO_SEGMENTATION | 2.6e-05 | 2.6e-04 | 1652 | 100 | 13 | AXIN2,BMP4,DKK1,DLL1,IRX3,MAFB,OSR1,PCSK6,SEMA3C,SMAD3,TBX18,TP53,WNT5A |
| GO_CARDIAC_VENTRICLE_MORPHOGENESIS | 2.7e-05 | 2.7e-04 | 1652 | 73 | 11 | CPE,ENG,FOXH1,GATA3,NOG,PPP1R13L,RXRA,SEMA3C,TGFBR3,TNNC1,TPM1 |
| GO_REGULATION_OF_CARDIAC_CONDUCTION | 2.7e-05 | 2.7e-04 | 1652 | 73 | 11 | ACE2,AGT,ANK2,ATP1A2,ATP1A4,CALM3,CASQ1,DMPK,FXYD3,NPR1,STIM1 |
| GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE | 2.8e-05 | 2.8e-04 | 1652 | 247 | 22 | ABL1,APOE,AXL,BAD,CD36,CYGB,DNMT3A,GPX1,GPX8,GSTA1,GSTM2,LRRK2,MGST2,NNT,PDGFD,PLEKHA1,PRKCD,PRXL2A,RDH11,SESN1,TP53,TRPM2 |
| GO_MICROTUBULE_BASED_MOVEMENT | 2.8e-05 | 2.8e-04 | 1652 | 283 | 24 | ACTR1B,ARMC4,BLOC1S1,BLOC1S4,BLOC1S5,CCDC151,CCDC40,DNAH10,DNAH3,FLOT2,ICK,IFT140,MAFIP,PURA,RABL2B,SPG11,STK36,SUN2,SYNE2,TRIM46,TRIP11,TTC30B,WDR60,WDR66 |
| GO_RECEPTOR_MEDIATED_ENDOCYTOSIS | 2.8e-05 | 2.8e-04 | 1652 | 320 | 26 | ACKR3,ANGPT1,AP2A1,APLN,APOC3,APOE,APOL1,C3,CACNG8,CAV3,CD36,DBNL,DKK1,DLL1,DNM1,FOLR1,HFE,HSPG2,JCHAIN,LRP1B,NLGN3,PIK3CB,RAMP1,SCARF1,SPARC,TBC1D5 |
| GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY | 2.8e-05 | 2.8e-04 | 1652 | 38 | 8 | PLXNB1,PLXNB2,PLXNB3,PLXNC1,SEMA3B,SEMA3C,SEMA3E,SEMA4A |
| GO_BIOMINERALIZATION | 2.9e-05 | 2.8e-04 | 1652 | 162 | 17 | AXIN2,BCOR,BMP4,CLEC3B,COL1A1,COL1A2,CYP27B1,FBXL15,FGR,GPM6B,MGP,OSR1,PKDCC,RSPO2,SMAD3,STIM1,WDR72 |
| GO_BODY_MORPHOGENESIS | 2.9e-05 | 2.8e-04 | 1652 | 49 | 9 | COL1A1,CRISPLD2,DAG1,DKK1,MMP2,NOG,PHLDB1,PLEKHA1,STRA6 |
| GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS | 2.9e-05 | 2.9e-04 | 1652 | 61 | 10 | AGPAT1,AGPAT4,AK3,CTPS2,ENTPD4,GPAM,NEIL1,NME3,NME4,SHMT1 |
| GO_CELLULAR_KETONE_METABOLIC_PROCESS | 3.0e-05 | 3.0e-04 | 1652 | 248 | 22 | ABCD1,ACADL,APOC3,APPL2,BMP5,CBR4,CNR1,COQ9,CYP17A1,DKK3,DKKL1,ELOVL5,GIP,GPD1,KMO,KYAT1,LPGAT1,PDP2,PNKD,REST,SLC7A7,STAR |
| GO_COFACTOR_BIOSYNTHETIC_PROCESS | 3.0e-05 | 2.9e-04 | 1652 | 230 | 21 | ACLY,ACSF3,BDH2,CBR4,CIAO3,COQ9,CPOX,ELOVL3,ELOVL5,HACD1,HACD2,KMO,MGST2,NUBPL,NUDT12,PANK1,PARP9,PDP2,SLC25A1,STAT3,TPK1 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 3.2e-05 | 3.2e-04 | 1652 | 777 | 48 | ADA,ADARB1,APOBEC3C,APOBEC3G,APOE,APPL2,B4GALT1,BAD,CADM1,CCDC87,CD36,CD4,CFL1,CNR1,CR1,CTSS,EIF2AK4,ERBIN,F2RL1,FGR,HEXIM1,IFITM2,IFITM3,IKBKB,IKBKE,MAPK3,MAVS,MMP12,MUC15,MYD88,NLRX1,PAK3,PARP9,PDE3A,PLB1,PLCB1,PLSCR1,POLR2L,PPM1B,PRKCD,PTPN22,RAF1,REST,RNASE10,TAB1,TASOR,TLR1,WNT5A |
| GO_POST_EMBRYONIC_DEVELOPMENT | 3.3e-05 | 3.2e-04 | 1652 | 88 | 12 | ABL1,BMP4,EFEMP1,GATA3,INPPL1,MYO1E,PLEKHA1,PPP1R13L,PYGO2,SELENOP,SEMA3C,STK36 |
| GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 3.4e-05 | 3.3e-04 | 1652 | 148 | 16 | ARPIN,CAV3,FHOD3,GMFB,INPP5J,KAT2B,LIMA1,LMOD1,PRKCD,SPTBN2,TMOD1,TMSB15B,TRIM37,TRIOBP,VIL1,VILL |
| GO_POSITIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT | 3.4e-05 | 3.3e-04 | 1652 | 39 | 8 | ALOX15B,BMP4,CYP27B1,HPSE,PLAAT4,PPARD,VDR,WNT5A |
| GO_TYPE_B_PANCREATIC_CELL_DEVELOPMENT | 3.4e-05 | 3.3e-04 | 1652 | 20 | 6 | BAD,BMP4,BMP5,DLL1,SIDT2,WNT5A |
| GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | 3.5e-05 | 3.4e-04 | 1652 | 181 | 18 | ACTN4,ACTR1B,BLOC1S1,BLOC1S4,BLOC1S5,FLOT2,HOOK2,ICK,IFT140,PURA,RABL2B,SPG11,SUN2,SYNE2,TRIM46,TRIP11,TTC30B,WDR60 |
| GO_EPITHELIAL_TUBE_FORMATION | 3.6e-05 | 3.5e-04 | 1652 | 133 | 15 | ABL1,BMP4,BMP5,CELSR1,CFL1,FOLR1,FZD6,GATA3,IRX3,NOG,OSR1,PLXNB2,RARG,SHROOM3,WNT5A |
| GO_ODONTOGENESIS | 3.6e-05 | 3.5e-04 | 1652 | 133 | 15 | AXIN2,BCOR,BMP4,COL1A1,COL1A2,ITGB4,LAMB1,LHX8,NFIC,OSR1,RSPO2,STIM1,TP63,WDR72,ZNF22 |
| GO_PHAGOCYTOSIS | 3.7e-05 | 3.6e-04 | 1652 | 364 | 28 | ABCA7,ABL1,APPL2,ARPC5,AXL,AZU1,C3,C4A,C4B,CD36,CRP,DOCK1,F2RL1,FCGR2A,FGR,IGHV3-73,LEPR,MAPK3,MYD88,MYO18A,NCKIPSD,PIK3CB,PIK3R1,PIK3R2,PLD4,PRKCD,PTPRC,SPG11 |
| GO_PRIMARY_ALCOHOL_METABOLIC_PROCESS | 3.7e-05 | 3.6e-04 | 1652 | 89 | 12 | ALDH3B1,BMP5,CBR4,DKK3,GPD1,PLB1,RDH11,RDH14,REST,SULT1A1,SULT1B1,SULT1E1 |
| GO_PROTEIN_PROCESSING | 3.7e-05 | 3.6e-04 | 1652 | 216 | 20 | ACE2,ADAMTS2,BAD,C1R,C1RL,CCBE1,CLEC3B,CPA3,CPE,CTSH,CTSS,CTSZ,GAS1,LRRK2,MME,OMA1,PCSK6,PCSK7,PSEN2,SERPINF2 |
| GO_REGULATION_OF_PROTEIN_POLYMERIZATION | 3.7e-05 | 3.6e-04 | 1652 | 216 | 20 | ABL1,ACTR3B,ARPC5,ARPIN,CAV3,CCR7,DBNL,FHOD3,FMN1,GMFB,INPP5J,LMOD1,PAK3,PRKCD,SPTBN2,TMOD1,TMSB15B,TRIOBP,VIL1,VILL |
| GO_FERTILIZATION | 3.8e-05 | 3.6e-04 | 1652 | 182 | 18 | ADAM21,AR,ATP1A4,B4GALT1,CCDC87,DKKL1,GLIPR1L1,H3-3A,HSPA1L,IGSF8,KLHL10,NR2F2,PLB1,PLCB1,PLCD4,RNASE10,SERPINA5,TDRD9 |
| GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 3.8e-05 | 3.6e-04 | 1652 | 182 | 18 | ABL1,ADA,DLL1,DOCK11,EIF2AK4,F2RL1,GATA3,GPR183,IL27RA,LOXL3,PARP3,PTPRC,RORC,SEMA4A,SOCS5,STAT3,TP53,ZBTB7B |
| GO_REGENERATION | 3.8e-05 | 3.6e-04 | 1652 | 199 | 19 | ANGPT2,AXL,CAPN3,CXCL12,DAG1,ENO3,FOLR1,GPX1,HFE,LAMB2,MSTN,PFKFB1,PPARD,PTPRU,RTN4RL1,SCARF1,SELENON,SPAAR,TGFBR3 |
| GO_FATTY_ACID_ELONGATION | 4.0e-05 | 3.8e-04 | 1652 | 13 | 5 | ABCD1,ELOVL3,ELOVL5,HACD1,HACD2 |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY | 4.0e-05 | 3.8e-04 | 1652 | 13 | 5 | CYP7B1,FOXH1,KANK2,TP63,ZNF366 |
| GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 4.0e-05 | 3.8e-04 | 1652 | 104 | 13 | BMP4,CTLA4,ERBB2,HOXA7,INHA,INPP5D,LOXL3,MAFB,PIAS3,PIK3R1,SOCS5,TOB2,ZBTB7B |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_BINDING | 4.0e-05 | 3.8e-04 | 1652 | 104 | 13 | CTSZ,DKK1,EFHB,HFE,LRRK2,MAPK3,NOG,PIN1,PRKCD,RIPOR2,SENP2,STYX,TLE5 |
| GO_PLASMA_MEMBRANE_ORGANIZATION | 4.0e-05 | 3.8e-04 | 1652 | 104 | 13 | ABCA7,ABCD1,ANK2,AR,CAV3,CAVIN2,EHD2,MTSS2,MYOF,PLSCR1,PLSCR4,PRKCD,PTPRC |
| GO_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION | 4.0e-05 | 3.8e-04 | 1652 | 51 | 9 | ABL1,CCL28,CCR7,CD36,DAG1,EPHA1,FMN1,SMAD3,UTRN |
| GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS_ENGULFMENT | 4.0e-05 | 3.8e-04 | 1652 | 13 | 5 | ABCA7,APPL2,C3,CD36,F2RL1 |
| GO_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT | 4.0e-05 | 3.8e-04 | 1652 | 76 | 11 | APOE,BHLHB9,CDKL5,CFL1,CUX2,DBNL,DLG5,ITSN1,LRRK2,NLGN3,PAK3 |
| GO_STEROL_TRANSPORT | 4.0e-05 | 3.8e-04 | 1652 | 104 | 13 | ABCA12,ABCA7,APOC3,APOE,CD36,CEL,CETP,LAMTOR1,LIMA1,OSBPL5,SCP2,STAR,TTC39B |
| GO_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 4.1e-05 | 3.9e-04 | 1652 | 90 | 12 | AXIN2,BMP4,BMP5,COL1A1,DAG1,ENG,MCRIP1,NOG,PBLD,PDPN,PHLDB1,SMAD3 |
| GO_POSITIVE_REGULATION_OF_CHEMOTAXIS | 4.3e-05 | 4.1e-04 | 1652 | 135 | 15 | AZU1,CCR7,CXCL12,F2RL1,IL6R,MAPK3,MEGF8,MSTN,PDGFD,PRKD1,RARRES2,RIPOR2,SMAD3,VEGFB,WNT5A |
| GO_STEROID_BIOSYNTHETIC_PROCESS | 4.3e-05 | 4.1e-04 | 1652 | 201 | 19 | ACLY,APOE,ASAH1,BMP5,CYP17A1,CYP27B1,CYP7B1,DKK3,DKKL1,GPAM,HSD17B1,HSD3B7,OSBPL9,REST,SCP2,SLC27A2,STAR,TRERF1,VDR |
| GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 4.3e-05 | 4.1e-04 | 1652 | 201 | 19 | ABL1,ADA,BCAR1,BTN3A3,CACNB3,CCR7,CD4,CTLA4,GATA3,IKBKB,INPP5D,KCNN4,PAK3,PIK3CB,PIK3R1,PIK3R2,PTPN22,PTPRC,PVRIG |
| GO_ALPHA_AMINO_ACID_CATABOLIC_PROCESS | 4.4e-05 | 4.1e-04 | 1652 | 105 | 13 | AASS,AUH,DDO,GPT,HOGA1,HPD,IVD,KMO,KYAT1,MCCC1,PRODH,SARDH,SHMT1 |
| GO_MICROTUBULE_BASED_TRANSPORT | 4.4e-05 | 4.1e-04 | 1652 | 184 | 18 | ACTR1B,BLOC1S1,BLOC1S4,BLOC1S5,CCDC40,FLOT2,ICK,IFT140,PURA,RABL2B,SPG11,STK36,SUN2,SYNE2,TRIM46,TRIP11,TTC30B,WDR60 |
| GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 4.4e-05 | 4.1e-04 | 1652 | 151 | 16 | AXL,BMP4,CTLA4,DLG5,ERBB2,FGR,HFE,INHA,INPP5D,LAX1,LOXL3,PARP3,PTPN22,RIPOR2,SOCS5,ZBTB7B |
| GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 4.4e-05 | 4.1e-04 | 1652 | 105 | 13 | BMP4,BMP5,CDKN1C,CDKN2B,ENG,FBXL15,FKBP8,GDF5,HFE,INHA,MSTN,RBPMS,TGFBR3 |
| GO_REGULATION_OF_RESPONSE_TO_WOUNDING | 4.4e-05 | 4.1e-04 | 1652 | 184 | 18 | APOE,CAPN3,CD36,F2R,F2RL1,HPSE,MYLK,PDPN,PPARD,PRKCD,RTN4RL1,SCARF1,SERPINF2,SMAD3,SPAAR,TSPAN8,VIL1,WFDC1 |
| GO_SENSORY_PERCEPTION_OF_PAIN | 4.4e-05 | 4.1e-04 | 1652 | 105 | 13 | BACE1,CACNB3,CNR1,CXCL12,F2R,GIP,GRM1,MAPK3,MC1R,MME,NIPSNAP1,NR2F6,SCN1A |
| GO_BONE_DEVELOPMENT | 4.5e-05 | 4.2e-04 | 1652 | 219 | 20 | AXIN2,BGN,BMP4,COL12A1,COL14A1,COL1A1,ENG,INPPL1,MEGF8,MEIS1,PDGFC,PLXNB1,PTPRC,RANBP3L,RARG,SLC38A10,SPARC,TAL1,TP53,TRIP11 |
| GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 4.5e-05 | 4.2e-04 | 1652 | 120 | 14 | ABL1,AGT,BCAR1,CHMP6,DOK1,EFEMP1,ERBIN,GPER1,GRB7,PDE6G,PIK3R1,PLCE1,SOCS5,VIL1 |
| GO_IMPORT_ACROSS_PLASMA_MEMBRANE | 4.5e-05 | 4.2e-04 | 1652 | 120 | 14 | AGT,ARL6IP5,ATP1A2,ATP1A4,CALCR,FOLR1,HFE,KCNJ16,KCNJ3,SLC12A9,SLC1A1,SLC9A9,TRPM2,WNK3 |
| GO_POSITIVE_REGULATION_OF_AUTOPHAGY | 4.5e-05 | 4.2e-04 | 1652 | 120 | 14 | BAD,EIF2AK4,LRRK2,MAPK3,PIK3CB,PIP4K2B,PLEKHF1,PRKD1,RNF152,SESN1,TFEB,TRIM22,ULK2,VPS13C |
| GO_MEMBRANE_DEPOLARIZATION | 4.6e-05 | 4.3e-04 | 1652 | 91 | 12 | ABCD1,ABL1,ANK2,ATP1A2,BEST2,BOK,CACNB3,CAV3,HSH2D,LRRK2,SCN1A,SCN2B |
| GO_POSITIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | 4.6e-05 | 4.2e-04 | 1652 | 21 | 6 | AGT,DAG1,FSCN1,PDPN,PHLDB1,SMAD3 |
| GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 4.7e-05 | 4.3e-04 | 1652 | 52 | 9 | ACTN4,ATP1A2,CAV3,FXYD3,HECW2,OSR1,SCN2B,UTRN,WNK3 |
| GO_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | 4.7e-05 | 4.3e-04 | 1652 | 52 | 9 | ABL1,ACTN4,DOCK1,EFNA5,FBLN1,LIMS2,PDPN,RAC3,TRIOBP |
| GO_REGULATION_OF_WOUND_HEALING | 4.7e-05 | 4.4e-04 | 1652 | 152 | 16 | APOE,CAPN3,CD36,F2R,F2RL1,HPSE,MYLK,PDPN,PPARD,PRKCD,SERPINF2,SMAD3,SPAAR,TSPAN8,VIL1,WFDC1 |
| GO_VESICLE_ORGANIZATION | 4.7e-05 | 4.3e-04 | 1652 | 330 | 26 | ANXA8,ANXA8L1,BLOC1S1,BLOC1S4,BLOC1S5,CHMP6,CTSZ,DNM1,EEA1,F2R,FOLR1,HOOK2,LAMTOR1,MYO18A,PLEKHF1,SEC16A,SEPTIN8,SPG11,STX10,TRAPPC2L,UNC13C,VPS28,VPS33B,VPS37D,VPS39,VPS41 |
| GO_RENAL_SYSTEM_PROCESS | 4.9e-05 | 4.5e-04 | 1652 | 121 | 14 | ADCY6,ADGRF5,AGT,BMP4,F2R,F2RL1,JCHAIN,KLHL3,MYO1E,NPR1,NPR3,OR51E2,PTPRO,SERPINF2 |
| GO_FORELIMB_MORPHOGENESIS | 5.0e-05 | 4.6e-04 | 1652 | 41 | 8 | EN1,FMN1,GDF5,OSR1,RSPO2,TP63,ZBTB16,ZNF358 |
| GO_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | 5.0e-05 | 4.6e-04 | 1652 | 41 | 8 | ABL1,AGT,DAG1,DPP4,FSCN1,PDPN,PHLDB1,SMAD3 |
| GO_SKELETAL_MUSCLE_TISSUE_REGENERATION | 5.0e-05 | 4.6e-04 | 1652 | 41 | 8 | CAPN3,DAG1,ENO3,GPX1,MSTN,PPARD,SELENON,SPAAR |
| GO_CARDIAC_CELL_DEVELOPMENT | 5.1e-05 | 4.7e-04 | 1652 | 92 | 12 | AGT,ALPK3,BMP4,CAV3,FHOD3,MYOM1,MYOM3,NEBL,OBSL1,PDCD4,PIN1,TGFBR3 |
| GO_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 5.1e-05 | 4.6e-04 | 1652 | 78 | 11 | BMP4,CDKN1C,GATA3,MEIS1,PYGO2,SIX5,SLITRK6,SMAD3,TBC1D32,TMOD1,WNT5A |
| GO_REGULATION_OF_BMP_SIGNALING_PATHWAY | 5.1e-05 | 4.7e-04 | 1652 | 92 | 12 | ABL1,BMP4,DAND5,DKK1,ENG,FBXL15,FKBP8,FSTL1,GDF5,NOG,PCSK6,WNT5A |
| GO_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 5.1e-05 | 4.6e-04 | 1652 | 491 | 34 | ABL1,ADA,AXL,BAD,BMP4,CCR7,CD4,CR1,CTLA4,DLG5,DPP4,ERBB2,FGR,FLOT2,GATA3,GPAM,GPR183,HFE,IGHV3-73,IL27RA,INHA,INPP5D,LAX1,LOXL3,NFAM1,PAK3,PARP3,PIK3R1,PTPN22,PTPRC,RIPOR2,SOCS5,ZBTB16,ZBTB7B |
| GO_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | 5.2e-05 | 4.7e-04 | 1652 | 65 | 10 | ENG,FOXH1,MYOM1,MYOM3,NOG,RXRA,TGFBR3,TNNC1,TPM1,WNT5A |
| GO_PROTEIN_LOCALIZATION_TO_CELL_SURFACE | 5.2e-05 | 4.7e-04 | 1652 | 65 | 10 | ABCA12,ABCA7,ANGPT1,ANK2,CAV3,FGF7,GPM6B,HFE,PTPRU,TAX1BP3 |
| GO_INTERACTION_WITH_HOST | 5.3e-05 | 4.9e-04 | 1652 | 204 | 19 | ACE2,ANPEP,AXL,BAD,CD4,CR1,DAG1,DPP4,EIF2AK4,HAVCR1,HYAL1,IFITM2,IFITM3,RXRA,SLC20A2,SLC52A1,SMAD3,ULK2,VAMP8 |
| GO_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 5.3e-05 | 4.9e-04 | 1652 | 170 | 17 | CACNG8,CALCR,CAV3,CHMP6,DKK1,DKK3,DKKL1,HFE,LDOC1,LYNX1,LYPD1,NLGN3,NOG,PRKCD,PSCA,SOCS5,TAL1 |
| GO_REGULATION_OF_SYNAPSE_ASSEMBLY | 5.4e-05 | 4.9e-04 | 1652 | 107 | 13 | ADGRL3,BHLHB9,CUX2,DKK1,DLG5,EFNA5,FLRT3,IL1RAPL2,LRRC24,NLGN3,SEMA4A,SLITRK6,WNT5A |
| GO_CELL_DIVISION | 5.5e-05 | 5.0e-04 | 1652 | 598 | 39 | ANAPC11,ANAPC13,ANAPC16,BCAR1,CABLES1,CALM3,CCND3,CFL1,CHMP6,CXCR5,DLL1,FGF7,GNAI1,KLHL22,LMLN,MPLKIP,PDGFC,PDGFD,PIK3CB,PIN1,POGZ,POU3F3,PPP1CB,RAB11FIP3,RBL2,RECQL5,REEP3,RTKN,SEPTIN11,SEPTIN8,SOX5,STOX1,TAL1,TP63,TRIOBP,TTC28,VEGFB,WASHC5,ZBTB16 |
| GO_RESPONSE_TO_ALCOHOL | 5.5e-05 | 5.0e-04 | 1652 | 240 | 21 | ADCY6,BAD,CALM3,CCR7,CLDN7,CNR1,CYP2E1,DAG1,DNMT3A,EFNA5,GATA3,GNAI1,HPGD,MSTN,PTGER2,RECQL5,SPARC,STAR,STAT3,TGFBR3,TP53 |
| GO_DETOXIFICATION | 5.6e-05 | 5.0e-04 | 1652 | 138 | 15 | APOE,CD36,CYGB,GPX1,GPX8,GSTA1,GSTM2,MARC2,MGST2,NNT,PDZK1,PRXL2A,RDH11,SESN1,SLC15A2 |
| GO_INTERLEUKIN_8_SECRETION | 5.6e-05 | 5.0e-04 | 1652 | 31 | 7 | CRP,F2R,F2RL1,PTPN22,SSC5D,TLR1,WNT5A |
Num: 2 (Pathways: 601 DK: 12)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (12) | BRSK1, CDK11B, CDK16, CSNK1G3, MAP3K21, MARK3, PHKG1, RIOK1, RIOK2, RPS6KL1, STK40, VRK2 |
| Light Kinase (35) | AURKA, CASK, CDK4, CDK8, CSNK1A1, CSNK2A1, DGKG, EIF2AK2, EPHA2, FLT1, GAK, HK2, HUNK, IRAK2, MAP2K1, MAP3K4, MAPK9, MAPKAPK3, MAPKAPK5, MARK2, PAK4, PDPK2P, PIM1, PIM2, PLK2, PLK3, PRKAA1, RPS6KB1, SGK3, TAF1, TBK1, TEX14, TRIB2, TRIB3, TRIM33 |
| Non-kinase Count | 1556 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_PEPTIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 736 | 177 | AARS1,ABCE1,AGO3,AIMP1,C8orf88,CARS1,CCL5,CDC123,CDK4,CHAC1,CNBP,CNOT1,CNOT7,COPS5,DAP3,DARS1,DHX36,DPH3,DRG2,EARS2,EEF1A1,EEF1D,EEF1G,EFL1,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ERAL1,ETF1,FARSB,GADD45GIP1,GARS1,GCLC,GCLM,GTPBP1,GTPBP2,HARS1,HBS1L,IARS1,IGF2BP3,IREB2,KARS1,LARS1,LRPPRC,LTN1,MAGOH,MAPKAPK5,MARS1,METTL16,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,NGDN,NOLC1,NPM1,NSUN4,PABPC4,PAIP2,PIWIL1,PIWIL2,PSTK,RACK1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL22L1,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP0P6,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS6KB1,RPS8,RPS9,RPSA,RSL24D1,RWDD1,SARS1,SERP1,SESN2,SHMT2,TARS1,TRAP1,TUFM,UBA52,UPF1,UPF3A,YARS1,YBX3,ZFP36 |
| GO_AMIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 876 | 185 | AARS1,ABCE1,AGO3,AIMP1,ASNS,B4GALT3,C8orf88,CARS1,CCL5,CDC123,CDK4,CERS1,CHAC1,CNBP,CNOT1,CNOT7,COPS5,DAP3,DARS1,DHX36,DPH3,DRG2,EARS2,EEF1A1,EEF1D,EEF1G,EFL1,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ERAL1,ETF1,FARSB,GADD45GIP1,GARS1,GCLC,GCLM,GTPBP1,GTPBP2,HARS1,HBS1L,IARS1,IGF2BP3,IREB2,KARS1,LARS1,LRPPRC,LTN1,MAGOH,MAPKAPK5,MARS1,METTL16,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,MTHFD1L,NGDN,NOLC1,NPM1,NSUN4,PABPC4,PAIP2,PIWIL1,PIWIL2,PRKAA1,PSTK,RACK1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL22L1,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP0P6,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS6KB1,RPS8,RPS9,RPSA,RSL24D1,RWDD1,SARS1,SERP1,SESN2,SHMT2,SMPD3,SPHK1,SPTLC2,TARS1,TRAP1,TUFM,UBA52,UPF1,UPF3A,YARS1,YBX3,ZFP36 |
| GO_PEPTIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 879 | 184 | AARS1,ABCE1,AGO3,AIMP1,C8orf88,CARS1,CCL5,CDC123,CDK4,CHAC1,CNBP,CNOT1,CNOT7,COPS5,DAP3,DARS1,DHX36,DNPEP,DPH3,DRG2,EARS2,EEF1A1,EEF1D,EEF1G,EFL1,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ERAL1,ETF1,FARSB,GADD45GIP1,GARS1,GCLC,GCLM,GLO1,GLRX2,GSTM5,GTPBP1,GTPBP2,HARS1,HBS1L,IARS1,IDE,IGF2BP3,IREB2,KARS1,LARS1,LRPPRC,LTN1,MAGOH,MAPKAPK5,MARS1,METTL16,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,NGDN,NLN,NOLC1,NPM1,NSUN4,PABPC4,PAIP2,PIWIL1,PIWIL2,PRNP,PSTK,RACK1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL22L1,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP0P6,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS6KB1,RPS8,RPS9,RPSA,RSL24D1,RWDD1,SARS1,SERP1,SESN2,SHMT2,TARS1,TRAP1,TUFM,UBA52,UPF1,UPF3A,YARS1,YBX3,ZFP36 |
| GO_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1603 | 99 | 76 | RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61A1,SEC61B,SRP68,SRPRA,UBA52,ZFAND2B |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM | 0.0e+00 | 0.0e+00 | 1603 | 112 | 78 | PMM2,RAB3GAP2,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61A1,SEC61B,SRP68,SRPRA,UBA52,ZFAND2B |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1859 | 256 | AARS1,ABCE1,ACOT7,ADK,ADORA2B,AGO3,AGPAT5,AIMP1,AK2,ALDH18A1,ALG10B,ALG14,ASNS,ATG7,B4GALT3,BCAT1,BCL10,BHMT2,C8orf88,CANT1,CARS1,CCL5,CDC123,CDK4,CERS1,CHAC1,CHDH,CNBP,CNOT1,CNOT7,COPS5,COX10,CSNK2A1,CTH,DAP3,DARS1,DDOST,DHX36,DPH3,DPM1,DPM2,DRG2,DSE,EARS2,EEF1A1,EEF1D,EEF1G,EFL1,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ERAL1,EREG,ETF1,FARSB,FUT2,FUT9,GADD45GIP1,GARS1,GCLC,GCLM,GFPT1,GFPT2,GPAT3,GPC6,GPT2,GSTM5,GTPBP1,GTPBP2,HAAO,HARS1,HBEGF,HBS1L,IARS1,IGF2BP3,IREB2,KARS1,KDSR,LARS1,LMAN1,LRPPRC,LTN1,MAGOH,MAPKAPK5,MARS1,MCFD2,METTL16,MFSD2A,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,MTCO2P12,MTHFD1L,MTR,MTRR,NADK,NAMPT,NGDN,NME2,NMT1,NOLC1,NPM1,NSUN4,NUS1,OAZ1,ODC1,PABPC4,PAIP2,PGM3,PHGDH,PHLDA1,PID1,PIGA,PIGL,PIWIL1,PIWIL2,PMM2,PNP,PRKAA1,PRMT1,PSAT1,PSTK,PYCR1,RAB3GAP2,RACK1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL22L1,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP0P6,RPLP1,RPLP2,RPN1,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS6KB1,RPS8,RPS9,RPSA,RSL24D1,RWDD1,SARS1,SEC24A,SELENOK,SERP1,SESN2,SHMT2,SLC35D2,SMPD3,SMS,SPHK1,SPTLC2,SRRD,ST3GAL4,SYVN1,TARS1,TBK1,TMEM106A,TMEM258,TRAP1,TRIB2,TUFM,TYW5,UBA52,UPF1,UPF3A,YARS1,YBX3,ZFP36 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1146 | 202 | AADAT,AARS1,ABCE1,ACBD6,ACOT7,ACOT9,AGO3,AIMP1,ASNS,B4GALT3,C8orf88,CARS1,CCL5,CDC123,CDK4,CERS1,CHAC1,CNBP,CNOT1,CNOT7,COPS5,DAP3,DARS1,DHX36,DLST,DNPEP,DPH3,DRG2,EARS2,EEF1A1,EEF1D,EEF1G,EFL1,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ERAL1,ETF1,FAR1,FARSB,GADD45GIP1,GARS1,GCLC,GCLM,GLO1,GLRX2,GSTM5,GTPBP1,GTPBP2,HARS1,HBS1L,IARS1,IDE,IGF2BP3,IREB2,KARS1,LARS1,LRPPRC,LTN1,MAGOH,MAPKAPK5,MARS1,METTL16,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,MTHFD1L,MTHFD2,MTRR,NGDN,NLN,NOLC1,NPM1,NSUN4,PABPC4,PAIP2,PGAM1,PIWIL1,PIWIL2,PPP2CA,PRKAA1,PRNP,PSTK,RACK1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL22L1,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP0P6,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS6KB1,RPS8,RPS9,RPSA,RSL24D1,RWDD1,SARS1,SERP1,SESN2,SHMT2,SMPD3,SPHK1,SPTLC2,TARS1,TRAP1,TUFM,UBA52,UPF1,UPF3A,YARS1,YBX3,ZFP36 |
| GO_TRANSLATIONAL_INITIATION | 0.0e+00 | 0.0e+00 | 1603 | 192 | 95 | ABCE1,C8orf88,CCL5,CDC123,COPS5,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF4H,EIF6,NPM1,PAIP2,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS6KB1,RPS8,RPS9,RPSA,UBA52 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY | 0.0e+00 | 0.0e+00 | 1603 | 120 | 79 | ETF1,MAGOH,NBAS,PPP2CA,PPP2R2A,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SKIV2L,UBA52,UPF1,UPF3A |
| GO_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 840 | 173 | A1CF,AGO3,AHCYL1,AKAP17A,BUD31,CDK11B,CEBPG,CNOT1,CNOT7,CTNNBL1,CWC15,DDIT3,DDX20,DDX39A,DDX47,DHX36,ECD,EDC3,EREG,ETF1,EXOSC1,GPKOW,GTPBP1,GTPBP2,HBS1L,IGF2BP3,LSM5,MAGOH,MEIOC,METTL16,MNAT1,MTREX,NBAS,NOCT,NPM1,NUP98,PABPC4,PDE12,PELO,PLRG1,POLR2C,POLR2H,POLR2J,PPIE,PPIL3,PPP2CA,PPP2R2A,PRMT5,PRPF3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PTBP2,RBM11,RBM19,RBM28,RNMT,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SAP18,SF3A1,SF3B6,SKIV2L,SMN1,SMN2,SMNDC1,SNRNP27,SNRPB2,SNU13,SNUPN,SRSF1,SRSF3,SRSF7,TARDBP,TENT2,TENT4B,THOC6,TRMT61A,TXNL4B,U2AF1,U2AF2,UBA52,UPF1,UPF3A,USP39,WDR33,WDR77,XPO1,XRN2,YBX1,YBX3,ZFP36,ZNF473,ZRANB2 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 1930 | 258 | AAAS,ABCE1,AHCYL1,AP1AR,AP1S2,AP3M2,AP3S2,AP4B1,APBA1,ARF4,ARFGAP3,ARFRP1,ARIH2,ARL1,ARL11,ARL13B,ARL17B,AURKA,BBIP1,BICD1,BOD1,BYSL,C17orf75,CCDC66,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC37,CEP290,CIB1,CNST,COPB1,COPB2,CRKL,DDIT3,DDX19B,DDX39A,DERL1,DHX36,DNAJC27,DNLZ,DYNC2LI1,EIF6,EMD,ENY2,EPB41,EPHA2,ETV5,EXOC3L2,EZH2,FAM126A,GAK,GET4,GNL3,GOLGA4,GOLPH3L,GOSR2,GPC6,HACL1,HAX1,HERPUD1,HK2,HSP90AA1,HSP90AB1,HSPA4,IDE,INTS13,IPO5,KATNB1,KDELR2,LARS1,LMAN1,M6PR,MAGOH,MAPRE1,MFHAS1,MON1A,MORC3,MSX1,NAPB,NEDD1,NMD3,NMT1,NOLC1,NOP53,NPM1,NUBP1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,OAZ1,PAM16,PAQR3,PDCD5,PID1,PIH1D1,PITRM1,PLK3,PLRG1,PMAIP1,PMM2,POT1,PPFIA1,PPHLN1,PRKAA1,PRNP,RAB24,RAB27A,RAB27B,RAB2A,RAB2B,RAB3GAP2,RACK1,RAPGEF6,RGPD5,RILPL1,RIOK2,RPF2,RPGR,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,RUVBL2,SAPCD2,SDAD1,SEC13,SEC23A,SEC24A,SEC24D,SEC61A1,SEC61B,SEL1L,SELENOS,SESN2,SGF29,SLC25A6,SNAP25,SNUPN,SNX27,SPRN,SRP68,SRPRA,SRSF1,SRSF3,SRSF7,SSNA1,STAC,STX19,SUMO1,SYNE3,SYS1,SYVN1,TARDBP,TBC1D10C,TBC1D14,TCP1,THOC6,TIMM13,TIMM23B,TIMM9,TMED1,TMED9,TMEM98,TNPO3,TOMM20,TOMM34,TXN,U2AF1,U2AF2,UBA52,UBE2D2,UBL4A,UPF1,WDR33,WRN,XPO1,XPO5,XPOT,YBX1,YWHAE,ZFAND1,ZFAND2B,ZFP36,ZW10 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1603 | 419 | 126 | ABCE1,ABT1,AGO3,BOP1,BUD23,BYSL,CEBPZ,DCAF13,DDX10,DDX18,DDX20,DDX21,DDX27,DDX47,DDX49,DICER1,DIMT1,EFL1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF6,EMG1,ERAL1,EXOSC1,FAM207A,GNL2,GTPBP10,GTPBP4,HSP90AA1,HSP90AB1,IMP4,METTL16,MRPL1,MRPL22,MTREX,NGDN,NLE1,NMD3,NOB1,NOLC1,NOP10,NOP14,NOP2,NOP53,NOP58,NPM1,NSUN4,NSUN5,NUP88,PELP1,PIH1D1,PRMT5,PRPF3,PTBP2,RIOK1,RIOK2,RPF1,RPF2,RPL10,RPL10A,RPL11,RPL12,RPL13A,RPL14,RPL23A,RPL24,RPL26,RPL27,RPL3,RPL35,RPL35A,RPL38,RPL5,RPL6,RPL7,RPLP0,RPLP0P6,RPP30,RPP40,RPS10,RPS14,RPS15,RPS16,RPS19,RPS2,RPS21,RPS24,RPS27,RPS28,RPS5,RPS6,RPS8,RPS9,RPSA,RRP15,RRP7A,RRP7BP,RSL1D1,RSL24D1,RUVBL2,SDAD1,SF3A1,SMN1,SMN2,SNU13,SNUPN,SRSF1,TENT4B,TFB1M,TFB2M,USP39,UTP15,UTP23,UTP4,UTP6,WDR43,WDR46,WDR77,XPO1,XRN2 |
| GO_RNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 404 | 123 | AEN,AGO3,CNOT1,CNOT7,DHX36,EDC3,ETF1,EXOSC1,GTPBP1,GTPBP2,HBS1L,IGF2BP3,LRPPRC,LSM5,MAGOH,MEIOC,METTL16,MTREX,NBAS,NOCT,NPM1,PABPC4,PDE12,PELO,PPP2CA,PPP2R2A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SKIV2L,SLFN13,TARDBP,TENT2,TENT4B,UBA52,UPF1,UPF3A,XPO1,XRN2,YBX1,YBX3,ZFP36 |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1180 | 197 | ADAMTS9,AEN,AGO3,ANAPC5,ARIH1,ARIH2,AURKA,C18orf25,CCDC47,CDC23,CDC26,CDC34,CLPX,CNOT1,CNOT7,CSNK1A1,CSNK2A1,DDIT3,DERL1,DFFA,DHX36,DICER1,DNAJB9,EDC3,ELOC,ETF1,EXOSC1,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,GTPBP1,GTPBP2,HBS1L,HERPUD1,HSP90AA1,HSP90AB1,IDE,IGF2BP3,KCTD5,KCTD6,KLHL8,LONP1,LRPPRC,LSM5,LTN1,MAGOH,MAPK9,MEIOC,METTL16,MTREX,N4BP1,NBAS,NGLY1,NOCT,NOP53,NPM1,NR1D1,OTUD7A,PABPC4,PAM16,PDCD6IP,PDE12,PELO,PLK2,PLK3,PMAIP1,PPP2CA,PPP2R2A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61B,SEL1L,SELENOS,SIAH2,SKIV2L,SLFN13,SMURF2,SUMO1,SYVN1,TAF1,TARDBP,TENT2,TENT4B,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,UPF1,UPF3A,USP12,USP15,USP24,USP42,XPO1,XRN2,YBX1,YBX3,YME1L1,ZFAND2B,ZFP36 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 208 | 93 | CNOT1,CNOT7,DHX36,EDC3,ETF1,EXOSC1,GTPBP2,HBS1L,LSM5,MAGOH,NBAS,NOCT,PDE12,PELO,PPP2CA,PPP2R2A,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SKIV2L,TENT2,TENT4B,UBA52,UPF1,UPF3A,ZFP36 |
| GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM | 0.0e+00 | 0.0e+00 | 1603 | 137 | 79 | KDELR2,PMM2,RAB3GAP2,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61A1,SEC61B,SRP68,SRPRA,UBA52,ZFAND2B |
| GO_VIRAL_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 1603 | 194 | 89 | AAAS,CCL5,EIF3D,GTF2B,NUP54,NUP58,NUP88,NUP93,NUP98,POLR2C,POLR2H,POLR2J,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC13,SMARCB1,TARDBP,TFAP4,TRIM11,UBA52,ZFP36 |
| GO_NCRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 471 | 127 | AARS1,ABT1,AGO3,AIMP1,BOP1,BUD23,BYSL,C2orf49,CARS1,CTU1,DARS1,DCAF13,DDX10,DDX18,DDX21,DDX27,DDX47,DDX49,DICER1,DIMT1,DPH3,DUS4L,EARS2,ELP2,EMG1,EPRS1,EXD1,EXOSC1,FAM207A,FARSB,GARS1,GTPBP4,HARS1,IARS1,IMP4,INTS10,INTS4,INTS6,KARS1,LARS1,MARS1,METTL1,METTL16,METTL2A,MRPL1,MRPL44,MTO1,MTREX,NGDN,NIFK,NOB1,NOLC1,NOP10,NOP14,NOP2,NOP53,NOP58,NSUN4,NSUN5,PELO,PELP1,PIH1D1,PIWIL1,PIWIL2,PLD6,PSTK,PUSL1,QTRT1,QTRT2,RIOK1,RIOK2,RPF1,RPF2,RPL10A,RPL11,RPL14,RPL26,RPL27,RPL35,RPL35A,RPL5,RPL7,RPP30,RPP40,RPS14,RPS15,RPS16,RPS19,RPS2,RPS21,RPS24,RPS27,RPS28,RPS6,RPS8,RPS9,RRP15,RRP7A,RRP7BP,RSL1D1,RTCB,RTRAF,SARS1,SLFN13,SNU13,TARS1,TENT2,TENT4B,TFB1M,TFB2M,THG1L,THUMPD3,TRIT1,TRMO,TRMT61A,TRNT1,TYW1B,TYW5,UTP15,UTP23,UTP4,UTP6,WDR43,WDR46,XPO5,XRN2,YARS1 |
| GO_RNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1603 | 917 | 169 | A1CF,AARS1,ABT1,AGO3,AHCYL1,AKAP17A,BICD1,BOP1,BUD23,BUD31,BYSL,C2orf49,CDK11B,CTNNBL1,CTU1,CWC15,DCAF13,DDX10,DDX18,DDX20,DDX21,DDX27,DDX39A,DDX47,DDX49,DHX36,DICER1,DIMT1,DPH3,DUS4L,ECD,ELP2,EMG1,EXOSC1,FAM207A,GPKOW,GTPBP4,IMP4,INTS10,INTS4,INTS6,KARS1,LSM5,MAGOH,MAP2K1,METTL1,METTL16,METTL2A,MNAT1,MRPL1,MRPL44,MTO1,MTREX,NGDN,NOB1,NOLC1,NOP10,NOP14,NOP2,NOP53,NOP58,NPM1,NSUN4,NSUN5,NUP98,PABPC4,PDE12,PELP1,PIH1D1,PIWIL2,PLRG1,POLR2C,POLR2H,POLR2J,PPIE,PPIL3,PPP2CA,PRMT5,PRPF3,PTBP2,PUSL1,QTRT1,QTRT2,RBM11,RBM19,RBM28,RIOK1,RIOK2,RNMT,RP9,RPF1,RPF2,RPL10A,RPL11,RPL14,RPL26,RPL27,RPL35,RPL35A,RPL5,RPL7,RPP30,RPP40,RPS13,RPS14,RPS15,RPS16,RPS19,RPS2,RPS21,RPS24,RPS27,RPS28,RPS6,RPS8,RPS9,RRP15,RRP7A,RRP7BP,RSL1D1,RTCB,RTRAF,SAP18,SARS1,SF3A1,SF3B6,SMN1,SMN2,SMNDC1,SNRNP27,SNRPB2,SNU13,SNUPN,SPOUT1,SRSF1,SRSF3,SRSF7,TARDBP,TENT2,TENT4B,TFB1M,TFB2M,THG1L,THOC6,THUMPD3,TMBIM6,TRIT1,TRMO,TRMT61A,TRNT1,TSN,TXNL4B,TYW1B,TYW5,U2AF1,U2AF2,USP39,UTP15,UTP23,UTP4,UTP6,WDR33,WDR43,WDR46,WDR77,XRN2,YBX1,ZNF473,ZRANB2 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 1151 | 188 | AAAS,ABCE1,AHCYL1,AP1S2,AP3M2,AP3S2,AP4B1,APBA1,ARF4,ARFGAP3,ARFRP1,ARIH2,ARL1,ARL11,ARL17B,C17orf75,CDC37,CEP290,CIB1,COPB1,COPB2,DDX19B,DDX39A,DERL1,DNAJC27,DNLZ,DYNC2LI1,EIF6,EMD,ENY2,GOSR2,HACL1,HAX1,HERPUD1,HSP90AA1,HSPA4,IDE,IPO5,KATNB1,LARS1,LMAN1,M6PR,MAGOH,MON1A,NAPB,NMD3,NOLC1,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,OAZ1,PAM16,PDCD5,PITRM1,PLK3,PMM2,PRKAA1,PRNP,RAB24,RAB27A,RAB27B,RAB2A,RAB2B,RAB3GAP2,RGPD5,RILPL1,RIOK2,RPGR,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SDAD1,SEC13,SEC23A,SEC24A,SEC24D,SEC61A1,SEC61B,SEL1L,SELENOS,SLC25A6,SNUPN,SNX27,SPRN,SRP68,SRPRA,SRSF1,SRSF3,SRSF7,SSNA1,STX19,SYVN1,TARDBP,TBC1D10C,TBC1D14,THOC6,TIMM13,TIMM23B,TIMM9,TMED1,TMED9,TNPO3,TOMM20,TOMM34,TXN,U2AF1,U2AF2,UBA52,UBE2D2,UPF1,WDR33,XPO1,XPO5,XPOT,YWHAE,ZFAND1,ZFAND2B |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 1603 | 944 | 171 | ARF4,ARFRP1,ARIH2,ARL1,ARL13B,AURKA,BBIP1,BICD1,BOD1,BYSL,CCDC66,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DDIT3,DNLZ,EZH2,GAK,GET4,GNL3,GOSR2,GPC6,HACL1,HAX1,HK2,HSP90AA1,HSPA4,IDE,INTS13,IPO5,KDELR2,LARS1,LMAN1,M6PR,MAPRE1,MFHAS1,MON1A,MORC3,MSX1,NEDD1,NMD3,NMT1,NOLC1,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,PAM16,PAQR3,PDCD5,PIH1D1,PITRM1,PLRG1,PMAIP1,PMM2,POT1,PPHLN1,PRKAA1,RAB3GAP2,RGPD5,RPF2,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,RUVBL2,SEC61A1,SEC61B,SESN2,SGF29,SLC25A6,SNAP25,SNUPN,SPRN,SRP68,SRPRA,SUMO1,SYS1,TARDBP,TCP1,TIMM13,TIMM23B,TIMM9,TMEM98,TNPO3,TOMM20,TOMM34,TXN,UBA52,UBE2D2,UBL4A,WRN,XPO1,YBX1,YWHAE,ZFAND2B,ZW10 |
| GO_CELLULAR_NITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 587 | 136 | AADAT,ACOT7,AEN,AGO3,APOBEC3A,APOBEC3D,CNOT1,CNOT7,DFFA,DHX36,DICER1,EDC3,ETF1,EXOSC1,GTPBP1,GTPBP2,HAAO,HBS1L,IGF2BP3,LRPPRC,LSM5,MAGOH,MEIOC,METTL16,MTREX,NBAS,NOCT,NPM1,NT5C,NUDT1,PABPC4,PAM16,PDE12,PDE4D,PDXP,PELO,PNP,PPP2CA,PPP2R2A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SKIV2L,SLFN13,TARDBP,TENT2,TENT4B,UBA52,UPF1,UPF3A,XPO1,XRN2,YBX1,YBX3,ZFP36 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1410 | 205 | ADAMTS9,AEN,AGO3,ANAPC5,ARIH1,ARIH2,ATG7,AURKA,C18orf25,CCDC47,CD44,CDC23,CDC26,CDC34,CLPX,CNOT1,CNOT7,CSNK1A1,CSNK2A1,DDIT3,DERL1,DFFA,DHX36,DICER1,DNAJB9,EDC3,EEF1A1,ELOC,ETF1,EXOSC1,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,GPC6,GPRASP1,GTPBP1,GTPBP2,HBS1L,HERPUD1,HSP90AA1,HSP90AB1,IDE,IGF2BP3,KCTD5,KCTD6,KLHL8,LONP1,LRPPRC,LSM5,LTN1,MAGOH,MAPK9,MEIOC,METTL16,MTREX,N4BP1,NBAS,NGLY1,NOCT,NOP53,NPM1,NR1D1,OAZ1,ODC1,OTUD7A,PABPC4,PAM16,PDCD6IP,PDE12,PELO,PHKG1,PLK2,PLK3,PMAIP1,PPP2CA,PPP2R2A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61B,SEL1L,SELENOS,SIAH2,SKIV2L,SLFN13,SMURF2,SUMO1,SYVN1,TAF1,TARDBP,TENT2,TENT4B,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,UPF1,UPF3A,USP12,USP15,USP24,USP42,XPO1,XRN2,YBX1,YBX3,YME1L1,ZFAND2B,ZFP36 |
| GO_RIBOSOME_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1603 | 290 | 101 | ABCE1,ABT1,BOP1,BUD23,BYSL,CEBPZ,DCAF13,DDX10,DDX18,DDX21,DDX27,DDX47,DDX49,DIMT1,EFL1,EIF6,EMG1,ERAL1,EXOSC1,FAM207A,GNL2,GTPBP10,GTPBP4,IMP4,METTL16,MRPL1,MRPL22,MTREX,NGDN,NLE1,NMD3,NOB1,NOLC1,NOP10,NOP14,NOP2,NOP53,NOP58,NPM1,NSUN4,NSUN5,NUP88,PELP1,PIH1D1,RIOK1,RIOK2,RPF1,RPF2,RPL10,RPL10A,RPL11,RPL12,RPL14,RPL23A,RPL24,RPL26,RPL27,RPL3,RPL35,RPL35A,RPL38,RPL5,RPL6,RPL7,RPLP0,RPLP0P6,RPP30,RPP40,RPS10,RPS14,RPS15,RPS16,RPS19,RPS2,RPS21,RPS24,RPS27,RPS28,RPS5,RPS6,RPS8,RPS9,RPSA,RRP15,RRP7A,RRP7BP,RSL1D1,RSL24D1,SDAD1,SNU13,TENT4B,TFB1M,TFB2M,UTP15,UTP23,UTP4,UTP6,WDR43,WDR46,XPO1,XRN2 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 1741 | 228 | AAAS,ABCE1,ADORA2B,AHCYL1,ANKRD27,ANKRD54,AP1AR,AP1S2,AP3M2,AP3S2,AP4B1,APBA1,AREG,ARF4,ARFGAP3,ARFRP1,ARIH2,ARL1,ARL11,ARL17B,BANF1,BICD1,C17orf75,CDC37,CEP290,CIB1,COG1,COPB1,COPB2,COPE,DDX19B,DDX20,DDX39A,DERL1,DNAJC27,DNLZ,DYNC1LI2,DYNC2LI1,EIF6,EIPR1,EMD,ENY2,GAK,GOSR2,GPRASP1,HACL1,HAX1,HERPUD1,HMGA1,HMGXB4,HSP90AA1,HSPA4,IDE,IL4R,IPO5,KATNB1,KDELR2,LARS1,LMAN1,LRPPRC,M6PR,MAGOH,MAP2K1,MCFD2,MON1A,MREG,MYO5B,NAPB,NMD3,NOLC1,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NUS1,NXT2,OAZ1,PAFAH1B1,PAM16,PDCD5,PITRM1,PLK3,PMM2,PRKAA1,PRKAB2,PRNP,RAB24,RAB27A,RAB27B,RAB2A,RAB2B,RAB3GAP2,RGPD5,RILPL1,RINT1,RIOK2,RPGR,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SDAD1,SEC13,SEC23A,SEC24A,SEC24D,SEC61A1,SEC61B,SEL1L,SELENOS,SLC25A6,SMN1,SMN2,SNUPN,SNX27,SPRN,SRP68,SRPRA,SRSF1,SRSF3,SRSF7,SSNA1,STX19,SYNE3,SYS1,SYVN1,TARDBP,TBC1D10C,TBC1D14,TFG,TGFA,THOC6,TIMM13,TIMM23B,TIMM9,TMED1,TMED9,TMEM167A,TNPO3,TOMM20,TOMM34,TRAPPC2B,TRAPPC6B,TXN,U2AF1,U2AF2,UBA52,UBE2D2,UPF1,UPF3A,UXT,VTA1,WDR33,XPO1,XPO5,XPOT,YWHAE,ZFAND1,ZFAND2B,ZW10 |
| GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 636 | 140 | AADAT,ACOT7,AEN,AGO3,ALDH8A1,APOBEC3A,APOBEC3D,CNOT1,CNOT7,DFFA,DHX36,DICER1,EDC3,ETF1,EXOSC1,GTPBP1,GTPBP2,HAAO,HBS1L,HSD17B14,IGF2BP3,IL4I1,LRPPRC,LSM5,MAGOH,MEIOC,METTL16,MTREX,NBAS,NOCT,NPM1,NT5C,NUDT1,PABPC4,PAM16,PDE12,PDE4D,PDXP,PELO,PNP,PON3,PPP2CA,PPP2R2A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SKIV2L,SLFN13,TARDBP,TENT2,TENT4B,UBA52,UPF1,UPF3A,XPO1,XRN2,YBX1,YBX3,ZFP36 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 1603 | 564 | 132 | ARIH2,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DDIT3,DNLZ,GOSR2,HACL1,HAX1,HK2,HSP90AA1,HSPA4,IDE,IPO5,LARS1,LMAN1,M6PR,MON1A,NMT1,NOLC1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,PAM16,PDCD5,PIH1D1,PITRM1,PMAIP1,PMM2,POT1,PRKAA1,RAB3GAP2,RGPD5,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,RUVBL2,SEC61A1,SEC61B,SGF29,SLC25A6,SNAP25,SNUPN,SPRN,SRP68,SRPRA,TARDBP,TCP1,TIMM13,TIMM23B,TIMM9,TNPO3,TOMM20,TOMM34,UBA52,UBE2D2,YWHAE,ZFAND2B |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1603 | 323 | 98 | ARFRP1,CIB1,CNST,GET4,GOLGA4,GOLPH3L,HSP90AA1,HSPA4,NMT1,PDCD5,PMAIP1,PRNP,RAB3GAP2,RACK1,RILPL1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61A1,SEC61B,SNAP25,SRP68,SRPRA,SYNE3,SYS1,TIMM13,TIMM9,UBA52,UBL4A,YWHAE,ZFAND2B |
| GO_NCRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1603 | 378 | 104 | AARS1,ABT1,AGO3,BOP1,BUD23,BYSL,C2orf49,CTU1,DCAF13,DDX10,DDX18,DDX21,DDX27,DDX47,DDX49,DICER1,DIMT1,DPH3,DUS4L,ELP2,EMG1,EXOSC1,FAM207A,GTPBP4,IMP4,INTS10,INTS4,INTS6,KARS1,METTL1,METTL16,METTL2A,MRPL1,MRPL44,MTO1,MTREX,NGDN,NOB1,NOLC1,NOP10,NOP14,NOP2,NOP53,NOP58,NSUN4,NSUN5,PELP1,PIH1D1,PUSL1,QTRT1,QTRT2,RIOK1,RIOK2,RPF1,RPF2,RPL10A,RPL11,RPL14,RPL26,RPL27,RPL35,RPL35A,RPL5,RPL7,RPP30,RPP40,RPS14,RPS15,RPS16,RPS19,RPS2,RPS21,RPS24,RPS27,RPS28,RPS6,RPS8,RPS9,RRP15,RRP7A,RRP7BP,RSL1D1,RTCB,RTRAF,SARS1,SNU13,TENT4B,TFB1M,TFB2M,THG1L,THUMPD3,TRIT1,TRMO,TRMT61A,TRNT1,TYW1B,TYW5,UTP15,UTP23,UTP4,UTP6,WDR43,WDR46,XRN2 |
| GO_PROTEIN_TARGETING_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1603 | 192 | 78 | CIB1,PRNP,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61A1,SEC61B,SRP68,SRPRA,UBA52,ZFAND2B |
| GO_PROTEIN_TARGETING | 0.0e+00 | 0.0e+00 | 1603 | 428 | 108 | AP4B1,ARIH2,CDC37,CIB1,DNLZ,GOSR2,HACL1,HAX1,HSP90AA1,HSPA4,IDE,KATNB1,LARS1,LMAN1,M6PR,MON1A,NUP54,PAM16,PDCD5,PITRM1,PMM2,PRKAA1,PRNP,RAB27A,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC61A1,SEC61B,SLC25A6,SRP68,SRPRA,TIMM13,TIMM23B,TIMM9,TOMM20,TOMM34,UBA52,UBE2D2,YWHAE,ZFAND2B |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 0.0e+00 | 1603 | 940 | 154 | AAAS,ABCE1,ABI2,AEN,AP1S2,APOBEC3A,APOBEC3D,ATG16L1,ATG7,BANF1,BICD1,CCL5,CNOT7,COPB1,CREB3,DERL1,DMBT1,EIF2AK2,EIF3D,EIF4H,ELOC,EPHA2,G3BP1,G3BP2,GADD45GIP1,GFI1,GTF2B,H2BC11,H2BC12,HAMP,HMGA1,HSP90AB1,IDE,IPO5,KARS1,KAT2A,KCTD5,MORC3,NECTIN1,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,PDCD6IP,PDE12,POLR2C,POLR2H,POLR2J,PPID,PPIE,PSMA4,PSMB1,PSMB3,RAC1,RACK1,RAD23A,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,RTRAF,SEC13,SLC1A5,SLC25A6,SMARCB1,SUGT1,SUMO1,TAF1,TAF4,TARDBP,TBK1,TBP,TCP1,TFAP4,TFRC,THOC6,TLR2,TRIM11,UBA52,UPF1,VRK2,VTA1,XPO1,XRCC6,YWHAE,ZFP36 |
| GO_RRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 221 | 77 | ABT1,BOP1,BUD23,BYSL,DCAF13,DDX10,DDX18,DDX21,DDX27,DDX47,DDX49,DIMT1,EMG1,EXOSC1,FAM207A,GTPBP4,IMP4,METTL16,MRPL1,MTREX,NGDN,NIFK,NOB1,NOLC1,NOP10,NOP14,NOP2,NOP53,NOP58,NSUN4,NSUN5,PELO,PELP1,PIH1D1,RIOK1,RIOK2,RPF1,RPF2,RPL10A,RPL11,RPL14,RPL26,RPL27,RPL35,RPL35A,RPL5,RPL7,RPP30,RPP40,RPS14,RPS15,RPS16,RPS19,RPS2,RPS21,RPS24,RPS27,RPS28,RPS6,RPS8,RPS9,RRP15,RRP7A,RRP7BP,RSL1D1,SLFN13,SNU13,TENT4B,TFB1M,TFB2M,UTP15,UTP23,UTP4,UTP6,WDR43,WDR46,XRN2 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 1782 | 198 | ABI2,ABT1,AGO3,AIM2,ANKRD27,AP1AR,APBA1,AREG,ARHGAP18,ARPC5L,ASF1A,ATG16L1,ATL1,BAIAP2L2,BCL10,BOP1,CAB39,CARMIL2,CCT2,CCT3,CCT8,CDC123,CENPN,COTL1,COX10,CSNK1A1,CTH,CUTC,DARS1,DDIT3,DDX20,DICER1,DYNC1LI2,EIF2AK2,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,EIF6,EPB41,EPPIN,EPRS1,ERAL1,FARSB,FAS,G3BP2,GOSR2,GTF2B,H2BC11,H2BC12,H2BC13,H2BC8,H3C14,H4C2,H4C3,H4C4,HACL1,HAX1,HCCS,HES1,HMGA1,HSP90AA1,HSP90AB1,HSPA4,IDE,KCNG1,KCNG4,KCTD3,KCTD5,KCTD6,LMAN1,LONP1,MAPK9,MAPRE1,MAX,MCFD2,MNAT1,MPP6,MYC,NAPB,NAV3,NDUFA5,NDUFAF2,NDUFAF4,NDUFAF7,NDUFB11,NIFK,NLE1,NME2,NOP2,NOP53,NPM1,NR1H2,NUP54,NUP58,NUP93,NUP98,ORC3,PANX1,PDCD6IP,PFKP,PFN2,PIH1D1,PIP4P1,PMAIP1,POLR1E,PPID,PRKAA1,PRMT1,PRMT5,PRNP,PRPF3,PSMC5,PSMD11,PSMD13,PSMD4,PSMG1,PSRC1,PTBP2,RAC1,RACK1,RAD23B,RAP1B,RAP1GDS1,RPF2,RPL10,RPL11,RPL12,RPL13A,RPL23A,RPL24,RPL3,RPL38,RPL5,RPL6,RPLP0,RPLP0P6,RPS10,RPS14,RPS15,RPS19,RPS27,RPS27A,RPS28,RPS3,RPS5,RPSA,RRP7A,RRP7BP,RSL24D1,RUVBL2,SEC13,SEC23A,SEC24A,SEC24D,SF3A1,SGF29,SHMT2,SLC1A2,SLC1A5,SLC7A9,SLIT2,SMARCB1,SMN1,SMN2,SNAP25,SNU13,SNUPN,SPAG1,SRSF1,SUMO1,TAF1,TAF6,TBCA,TBP,TBX20,TCP1,TFAP4,TFG,TGFA,THG1L,TMEM126B,TMEM70,TMOD3,TOMM20,TRAPPC6B,UBA52,USP39,WDR77,YME1L1,ZMYND10,ZNF207,ZW10 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1603 | 625 | 113 | ARFRP1,ARL13B,BBIP1,CIB1,CNST,CRKL,EPHA2,ETV5,FAM126A,GAK,GET4,GOLGA4,GOLPH3L,GPC6,HSP90AA1,HSPA4,NMT1,NUP54,PDCD5,PID1,PMAIP1,PPFIA1,PRNP,RAB3GAP2,RACK1,RAPGEF6,RILPL1,RPL10,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL26,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL5,RPL6,RPL7,RPL8,RPL9,RPLP0,RPLP1,RPLP2,RPS10,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS25,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS3A,RPS4X,RPS5,RPS6,RPS8,RPS9,RPSA,SEC23A,SEC61A1,SEC61B,SNAP25,SRP68,SRPRA,SSNA1,STAC,SYNE3,SYS1,TIMM13,TIMM9,UBA52,UBL4A,YWHAE,ZFAND2B |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 1864 | 198 | AAAS,ADAMTS1,ANAPC5,ANXA1,ASNS,AURKA,BANF1,BCAT1,BCCIP,BIN3,BOD1,BOP1,BORA,BRSK1,BTG3,C10orf90,CAB39,CBX3,CCDC124,CCDC36,CCNC,CCNJ,CCSAP,CDC123,CDC23,CDC26,CDC34,CDC37,CDK11B,CDK16,CDK4,CDK8,CEP290,CEP85,CEP97,CHTF8,CIB1,CNOT1,CNOT7,COPS5,CRY1,CSNK1A1,CSNK2A1,DDIT3,E2F6,E2F7,ECD,EIF4EBP1,EMD,EPB41,EPGN,EREG,ERF,EVI2B,EXD1,EZH2,FAM9C,FBXO43,FGF8,FOSL1,GADD45A,GADD45GIP1,GAK,GATA6,GFI1,GNAI3,GPR3,GTPBP4,HES1,HSP90AA1,HSP90AB1,HUS1,ING1,INTS13,IPO5,KAT2A,KATNA1,KATNB1,LIG3,LIN52,MAP2K1,MAPRE1,MAX,MEIOC,MITD1,MNAT1,MSTO1,MSX1,MYC,NAA50,NBN,NEDD1,NLE1,NOLC1,NOP53,NPM1,NUBP1,NUDC,NUP88,ORC3,ORC4,OSGIN2,PAFAH1B1,PAK4,PCGF6,PDCD6IP,PDXP,PELO,PHGDH,PHLDA1,PIM1,PIM2,PIWIL1,PIWIL2,PLD6,PLK2,PLK3,PLRG1,POC5,POLD2,POLE4,PPM1D,PPP2CA,PPP2R2A,PRIM2,PRKAA1,PRKAB2,PRMT1,PRMT5,PRNP,PRR5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RACK1,RAD23A,RAD51B,RAD9A,RHEB,RHNO1,RINT1,RIOK2,RMI2,RNF2,RPL23,RPL24,RPL26,RPS15A,RPS3,RPS6,RPS6KB1,RTTN,SAPCD2,SHCBP1L,SIAH2,SLC16A1,SMARCB1,SMPD3,SPHK1,SPIN2A,SPOUT1,SPRY2,SSNA1,SUGT1,TAF1,TAF6,TARDBP,TENT4B,TERB2,TEX14,TFAP4,TGFA,TIPIN,TMOD3,TRIM36,TUBD1,TUBE1,TXNL4B,UPF1,USP39,UXT,WBP2NL,XPO1,YWHAE,ZNF207,ZW10 |
| GO_CYTOPLASMIC_TRANSLATION | 0.0e+00 | 0.0e+00 | 1603 | 99 | 48 | AARS1,CNBP,DHX36,DPH3,DRG2,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,ETF1,RPL10A,RPL11,RPL13A,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL22L1,RPL24,RPL26,RPL29,RPL30,RPL31,RPL32,RPL35A,RPL36,RPL36A,RPL38,RPL39,RPL6,RPL8,RPL9,RPLP0,RPLP0P6,RPLP1,RPS21,RPS23,RPS28,RPS29,RPSA,RWDD1,YBX3 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 193 | 58 | ABT1,AGO3,BOP1,DDX20,DICER1,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF6,ERAL1,HSP90AA1,HSP90AB1,NLE1,NOP2,NOP53,PIH1D1,PRMT5,PRPF3,PTBP2,RPF2,RPL10,RPL11,RPL12,RPL13A,RPL23A,RPL24,RPL3,RPL38,RPL5,RPL6,RPLP0,RPLP0P6,RPS10,RPS14,RPS15,RPS19,RPS27,RPS28,RPS5,RPSA,RRP7A,RRP7BP,RSL24D1,RUVBL2,SF3A1,SMN1,SMN2,SNU13,SNUPN,SRSF1,USP39,WDR77,ZFAND1 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 1036 | 128 | ABI2,ABT1,AGO3,ANKRD27,AP1AR,ARHGAP18,ARPC5L,ASF1A,BAIAP2L2,BOP1,CARMIL2,CCT2,CENPN,COTL1,COX10,DDX20,DICER1,EIF2AK2,EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF6,ERAL1,GTF2B,H2BC11,H2BC12,H2BC13,H2BC8,H3C14,H4C2,H4C3,H4C4,HAX1,HCCS,HSP90AA1,HSP90AB1,HSPA4,LONP1,MAPRE1,MNAT1,NAPB,NAV3,NDUFA5,NDUFAF2,NDUFAF4,NDUFAF7,NDUFB11,NLE1,NOP2,NOP53,NPM1,NUP93,NUP98,ORC3,PFN2,PIH1D1,PIP4P1,POLR1E,PRMT5,PRPF3,PSMC5,PSMD11,PSMD13,PSMD4,PSMG1,PSRC1,PTBP2,RAC1,RAD23B,RAP1GDS1,RPF2,RPL10,RPL11,RPL12,RPL13A,RPL23A,RPL24,RPL3,RPL38,RPL5,RPL6,RPLP0,RPLP0P6,RPS10,RPS14,RPS15,RPS19,RPS27,RPS27A,RPS28,RPS3,RPS5,RPSA,RRP7A,RRP7BP,RSL24D1,RUVBL2,SF3A1,SGF29,SLIT2,SMARCB1,SMN1,SMN2,SNAP25,SNU13,SNUPN,SPAG1,SRSF1,TAF1,TAF6,TBCA,TBP,TBX20,TCP1,TMEM126B,TMEM70,TMOD3,TOMM20,UBA52,USP39,WDR77,ZMYND10,ZNF207 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1988 | 182 | ABT1,ADORA2B,ALG10B,ANXA1,ARF4,ASF1A,ATF3,BCL10,BRPF1,BUD31,CASK,CCL5,CCNC,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC123,CDK4,CDK8,CEBPG,CEBPZ,CEP290,CHCHD2,CHTF8,CNBP,CNOT7,COPS5,CREB3,CREB5,CREM,CXXC1,DDIT3,DHX36,DLX2,E2F6,E2F7,ECD,EIF2S3,EIF3C,EIF3D,EIF5A2,EIF6,ELK4,ELOC,EN2,ENY2,EREG,ESRRG,ETV4,ETV5,FHL2,FOSB,FOSL1,FOXA2,FOXC2,FOXF2,GABPB1,GABPB2,GATA6,GFI1,GNL3,GPBP1,GTF2B,HAX1,HDAC4,HES1,HMGA1,HOXA3,HRH1,HSP90AA1,HSP90AB1,IER2,IER5,IL23A,ILF2,ING1,KARS1,KAT2A,KAT8,KLF10,LDB2,LYL1,MAFF,MAP2K1,MAP3K4,MAPKAPK5,MARS1,MAX,MED26,MMS19,MNAT1,MORF4L2,MSX1,MTCO2P12,MTDH,MTF1,MYC,MYT1L,NAA15,NAMPT,NEUROD2,NFYA,NIBAN2,NIF3L1,NMD3,NME2,NOLC1,NPM1,NR1D1,NR1D2,NR1H2,NSUN4,NUP98,PCGF6,PELP1,PHF19,PID1,PIH1D1,PIM1,PIM2,PIWIL2,PNKP,POT1,PRKAA1,PRMT1,PSMC5,PSRC1,RAB3GAP2,RAC1,RACK1,RFX2,RFX3,RGMB,RPL26,RPL30,RPL5,RPS27A,RPS4X,RPS6KB1,RPS9,RTRAF,RUNX1,RUVBL2,SERP1,SESN2,SETD3,SIM2,SMAD5,SMARCB1,SMPD3,SS18L1,TAF1,TAF4,TAF4B,TBK1,TBP,TBX20,TCEA1,TCP1,TFAP2C,TFAP4,TFB2M,TLR2,UBA52,UPF3A,UTP15,WBP2NL,WDR43,WDR77,XRCC6,YBX1,YBX3,ZC3H8,ZCCHC18,ZIC2,ZNF143,ZNF567,ZNF609 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 1603 | 1114 | 129 | AAAS,ANAPC5,ARIH1,ARIH2,ATG7,BCL10,BLMH,C10orf90,C18orf25,CDC23,CDC26,CDC34,COPS5,CRY1,CTU1,DCAF13,DERL1,EIPR1,ELOC,ENY2,FBXL5,FBXO10,FBXO38,FBXO43,FEM1C,FOXF2,GCLC,GID4,GNL3,GTPBP4,H2BC11,H2BC12,H2BC13,H2BC8,HDAC4,HECTD2,HERC4,HERPUD1,HSP90AA1,HSP90AB1,KAT2A,KCTD6,KLHL2,KLHL8,LTN1,MAPK9,MARCHF3,MARCHF4,MED8,MYC,N4BP1,NEUROD2,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,OTUD7A,OTULIN,PCGF6,PELI2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF114,RNF145,RNF181,RNF19A,RNF2,RPL11,RPL23,RPL5,RPS2,RPS27A,RPS3,SEL1L,SELENOS,SHMT2,SIAH2,SMURF2,SOCS7,SPATA2,SPHK1,STAMBPL1,SUMO1,SVBP,SYVN1,TAF1,TOMM20,TPP2,TRAF3,TRIB3,TRIM11,TRIM33,TRIM36,U2AF2,UBA5,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,UFM1,UNKL,USP12,USP15,USP24,USP39,USP42,ZNF451 |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 1224 | 134 | ADAMTS1,ANAPC5,ANXA1,ASNS,AURKA,BCCIP,BOP1,BORA,BRSK1,BTG3,C10orf90,CAB39,CBX3,CCDC36,CCNC,CCNJ,CCSAP,CDC123,CDC23,CDC26,CDC37,CDK11B,CDK16,CDK4,CDK8,CEP290,CEP85,CEP97,CNOT1,CNOT7,COPS5,CRY1,CSNK2A1,DDIT3,E2F6,E2F7,ECD,EIF4EBP1,EPGN,EREG,EVI2B,EZH2,FBXO43,FGF8,FOSL1,GADD45A,GADD45GIP1,GATA6,GPR3,GTPBP4,HES1,HSP90AA1,HSP90AB1,HUS1,INTS13,IPO5,KAT2A,LIN52,MAP2K1,MAPRE1,MAX,MEIOC,MNAT1,MSX1,MYC,NBN,NEDD1,NLE1,NOP53,NPM1,NUBP1,PAFAH1B1,PCGF6,PDCD6IP,PDXP,PIM2,PIWIL2,PLK2,PLK3,PLRG1,PRKAA1,PRKAB2,PRMT1,PRMT5,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RACK1,RAD23A,RAD51B,RAD9A,RHEB,RHNO1,RINT1,RIOK2,RMI2,RNF2,RPL23,RPL24,RPL26,RPS15A,RPS6,RPS6KB1,SMPD3,SPHK1,SPIN2A,SSNA1,TAF1,TAF6,TARDBP,TEX14,TFAP4,TGFA,TIPIN,TMOD3,TRIM36,UXT,XPO1,YWHAE,ZNF207,ZW10 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1870 | 171 | ABT1,ADORA2B,ARF4,ASF1A,ATF3,BCL10,BRPF1,BUD23,BUD31,CASK,CCNC,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDK8,CEBPG,CEBPZ,CEP290,CHCHD2,CHTF8,CNBP,CNOT1,CNOT7,COPS5,CREB3,CREB5,CREM,CXXC1,DDIT3,DHX36,DIMT1,DLX2,E2F6,E2F7,ECD,ELK4,ELOC,EN2,ENY2,ESRRG,ETV4,ETV5,FHL2,FOSB,FOSL1,FOXA2,FOXC2,FOXF2,GABPB1,GABPB2,GATA6,GFI1,GNL3,GPBP1,GTF2B,GTPBP1,HAX1,HDAC4,HES1,HMGA1,HOXA3,HSP90AA1,HSP90AB1,IER2,IER5,IL23A,ILF2,ING1,KARS1,KAT2A,KAT8,KLF10,LDB2,LYL1,MAFF,MAP2K1,MAP3K4,MAPKAPK5,MARS1,MAX,MED26,METTL16,MMS19,MNAT1,MORF4L2,MSX1,MTCO2P12,MTDH,MTF1,MYC,MYT1L,NAA15,NAMPT,NBN,NEUROD2,NFYA,NIBAN2,NIF3L1,NMD3,NME2,NOLC1,NPM1,NR1D1,NR1D2,NR1H2,NUP98,PCGF6,PELP1,PHF19,PID1,PIH1D1,PIM1,PIM2,PNKP,POT1,PRKAA1,PSMC5,PSRC1,RFX2,RFX3,RGMB,RIOK1,RIOK2,RPS27A,RPS3,RTRAF,RUNX1,RUVBL2,SESN2,SETD3,SHLD3,SIM2,SMAD5,SMARCB1,SS18L1,TAF1,TAF4,TAF4B,TBK1,TBP,TBX20,TCEA1,TCP1,TFAP2C,TFAP4,TFB2M,TFRC,TLR2,TMEM161A,U2AF2,UBA52,UBE2V2,UPF1,UTP15,WBP2NL,WDR43,WDR77,WRN,XRCC6,YBX1,ZC3H8,ZCCHC18,ZFP36,ZIC2,ZNF143,ZNF567,ZNF609 |
| GO_RIBOSOME_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 62 | 34 | ABT1,BOP1,EFL1,EIF6,ERAL1,MRPL22,NLE1,NOP2,NOP53,NPM1,NSUN4,RPF2,RPL10,RPL11,RPL12,RPL23A,RPL24,RPL3,RPL38,RPL5,RPL6,RPLP0,RPLP0P6,RPS10,RPS14,RPS15,RPS19,RPS27,RPS28,RPS5,RPSA,RRP7A,RRP7BP,RSL24D1 |
| GO_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1399 | 143 | AAAS,ADAMTS1,ANAPC5,ANXA1,AURKA,BANF1,BCAT1,BCCIP,BIN3,BOD1,BORA,BRSK1,C10orf90,CAB39,CBX3,CCDC36,CCNJ,CCSAP,CDC123,CDC23,CDC26,CDC34,CDK4,CEP290,CEP85,CEP97,CHTF8,CNOT1,CNOT7,CSNK2A1,DDIT3,E2F6,E2F7,ECD,EIF4EBP1,EMD,EPGN,EREG,EVI2B,EZH2,FBXO43,FGF8,GADD45A,GADD45GIP1,GATA6,GFI1,GPR3,HSP90AA1,HSP90AB1,HUS1,INTS13,KAT2A,KATNB1,MAP2K1,MAPRE1,MAX,MEIOC,MITD1,MNAT1,MSTO1,MSX1,MYC,NAA50,NBN,NEDD1,NOP53,NPM1,NUBP1,ORC3,ORC4,PAFAH1B1,PCGF6,PDCD6IP,PDXP,PHGDH,PHLDA1,PIM2,PIWIL2,PLK2,PLK3,PLRG1,POLD2,POLE4,PPM1D,PPP2CA,PPP2R2A,PRIM2,PRKAA1,PRKAB2,PRMT1,PRMT5,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RAD51B,RAD9A,RHEB,RHNO1,RINT1,RIOK2,RMI2,RNF2,RPL23,RPL24,RPL26,RPS3,RPS6,RPS6KB1,RTTN,SAPCD2,SHCBP1L,SLC16A1,SMPD3,SPRY2,SSNA1,TAF1,TERB2,TEX14,TFAP4,TGFA,TIPIN,TMOD3,TRIM36,TUBE1,UPF1,UXT,XPO1,YWHAE,ZNF207,ZW10 |
| GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 1603 | 861 | 109 | AAAS,AARS1,AGO3,C8orf88,CCL5,CDC123,CDC37,CDK4,CNBP,CNOT1,CNOT7,DHX36,DICER1,DPH3,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S3,EIF3C,EIF3D,EIF3K,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ETF1,EXOSC1,GTPBP2,H3C14,H4C2,H4C3,H4C4,IGF2BP3,IREB2,LRPPRC,LTN1,MAGOH,MAP2K1,MAPKAPK5,MEIOC,METTL16,MRPL44,NGDN,NOCT,NOLC1,NPM1,NSUN4,NUP54,NUP58,NUP88,NUP93,NUP98,PABPC4,PAIP2,PDE12,PIWIL1,PIWIL2,POLR2C,POLR2H,POLR2J,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RPL10,RPL13A,RPL26,RPL30,RPL38,RPL5,RPLP1,RPS14,RPS27A,RPS3,RPS4X,RPS6KB1,RPS9,SEC13,SERP1,SESN2,SHMT2,SPOUT1,TARDBP,TENT2,TENT4B,TRAP1,TSN,UBA52,UPF1,UPF3A,XPO1,XPO5,YBX1,YBX3,ZFP36 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 0.0e+00 | 1603 | 912 | 112 | AAAS,ANAPC5,ARIH1,ARIH2,ATG7,BCL10,BLMH,C10orf90,C18orf25,CDC23,CDC26,CDC34,CRY1,CTU1,DCAF13,DERL1,EIPR1,ELOC,FBXL5,FBXO10,FBXO38,FBXO43,FEM1C,FOXF2,GCLC,GID4,GNL3,GTPBP4,H2BC11,H2BC12,H2BC13,H2BC8,HDAC4,HECTD2,HERC4,HERPUD1,HSP90AA1,HSP90AB1,KCTD6,KLHL2,KLHL8,LTN1,MAPK9,MARCHF3,MARCHF4,MED8,N4BP1,NEUROD2,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,OTULIN,PCGF6,PELI2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RFFL,RNF114,RNF145,RNF181,RNF19A,RNF2,RPL11,RPL23,RPL5,RPS2,RPS27A,RPS3,SEL1L,SELENOS,SIAH2,SMURF2,SOCS7,SPHK1,SUMO1,SVBP,SYVN1,TAF1,TPP2,TRAF3,TRIB3,TRIM11,TRIM33,TRIM36,U2AF2,UBA5,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,UFM1,UNKL,ZNF451 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1962 | 171 | AAAS,AADAT,AARS1,ABCB11,ABCG2,ABHD10,ACBD6,ACOT7,ACOT9,ADK,ADORA2B,AGPAT5,AHCYL1,AIMP1,AK2,ALDH18A1,ALDH8A1,ANXA1,APOBEC3A,APOBEC3D,ASNS,ATF3,B4GALT3,BCAT1,BHMT2,BLMH,BPGM,CARS1,CASK,CD320,CD44,CNBP,COQ10B,COQ6,CREM,CRY1,CTH,CYP2C19,DARS1,DLST,DPM1,DPM2,DSE,DUSP12,EARS2,ECD,EFL1,EIF6,EPHA2,EPRS1,ERFE,FAR1,FARSB,FDX2,FOXA2,FUT2,FUT9,GARS1,GCLC,GCLM,GFI1,GFPT1,GFPT2,GLO1,GLYATL1,GLYATL2,GNAI3,GNPDA1,GNPDA2,GPAT3,GPT2,GTPBP1,HAAO,HACL1,HARS1,HDAC4,HK2,HRH1,IARS1,IL4I1,IMPA1,IMPAD1,IREB2,KARS1,KAT2A,KDSR,LARS1,LIAS,MARS1,MMADHC,MTCO2P12,MTHFD1L,MTHFD2,MTR,MTRR,NADK,NAMPT,NANS,NFYA,NLN,NME2,NMT1,NR1D1,NR1H2,NT5C,NUDT1,NUP54,NUP58,NUP88,NUP93,NUP98,NUS1,OAZ1,ODC1,PDE4D,PDXP,PFKP,PGAM1,PGM3,PHGDH,PID1,PIM1,PIP4P1,PMAIP1,PMM2,PNKP,PNP,PON3,PRDX4,PRKAA1,PRKAB2,PSAT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PYCR1,SARS1,SEC13,SELENOS,SERP1,SESN2,SHMT2,SLC16A1,SLC35A2,SLC35A3,SLC35D2,SMPD3,SMS,SPHK1,SPTLC2,ST3GAL4,TARS1,TLR2,TRIB3,TXN,TYR,UAP1,UBIAD1,UEVLD,YARS1 |
| GO_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 1030 | 117 | AAAS,ADAMTS1,ANAPC5,ANXA1,ASNS,AURKA,BANF1,BCAT1,BCCIP,BOD1,BORA,BRSK1,BTG3,CCNJ,CCSAP,CDC23,CDC26,CDC34,CDK11B,CDK4,CEP290,CEP85,CEP97,CHTF8,CIB1,CNOT1,CNOT7,E2F6,E2F7,ECD,EIF4EBP1,EMD,EPGN,EREG,ERF,EZH2,FGF8,GADD45A,GADD45GIP1,GFI1,HES1,HSP90AA1,HUS1,INTS13,KATNB1,MAPRE1,MAX,MEIOC,MITD1,MNAT1,MSTO1,MYC,NAA50,NBN,NEDD1,NLE1,NOLC1,NOP53,NUP88,ORC3,ORC4,PAFAH1B1,PDCD6IP,PDXP,PHLDA1,PIM2,PLK2,PLK3,PLRG1,POLE4,PPM1D,PPP2CA,PPP2R2A,PRIM2,PRMT1,PRMT5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RAD51B,RAD9A,RINT1,RIOK2,RNF2,RPL24,RPL26,RPS6,RPS6KB1,SAPCD2,SMPD3,SPHK1,SPRY2,SSNA1,SUGT1,TEX14,TFAP4,TGFA,TIPIN,TMOD3,TRIM36,TUBD1,TUBE1,YWHAE,ZNF207,ZW10 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1603 | 1994 | 169 | ABI2,ADM2,ADORA2B,ANKRD54,AREG,ATF3,AURKA,BCAR3,BCCIP,BORA,BRSK1,C9orf72,CAB39,CASK,CCL20,CCL5,CCNC,CCNJ,CD44,CDC37,CDK11B,CDK16,CDK4,CDK8,CEP85,CIB1,CNOT7,COPS5,CRKL,CRY1,CSNK1A1,CSNK1G3,CSNK2A1,DNAJC27,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EIF2S1,EPGN,EPHA2,EREG,EZH2,FAS,FGF8,FLT1,GADD45A,GAK,GDF15,GTPBP4,HAX1,HBEGF,HES1,HSP90AA1,HSP90AB1,HUNK,HUS1,IL23A,INHBE,IPO5,IRAK2,KARS1,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPK9,MAPKAPK3,MAPKAPK5,MARK2,MARK3,MFHAS1,MNAT1,MOB2,MORC3,MYC,NBN,NME2,NOP53,NPM1,PAFAH1B1,PAK4,PAQR3,PDE4D,PDGFA,PELI2,PFN2,PHKG1,PID1,PIH1D1,PIM1,PIM2,PLK2,PLK3,PPM1D,PPP2CA,PRDX4,PRKAA1,PRKAB2,PRKAR1B,PRMT1,PRMT5,PRNP,PRR5,PRRC1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RAC1,RACK1,RAP1B,RELL1,RGS4,RIOK1,RIOK2,RPLP1,RPS27A,RPS3,RPS6KB1,RPS6KL1,RTRAF,SEMA3A,SESN2,SGK3,SLIT2,SMAD5,SMPD3,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,TAF1,TARDBP,TBC1D10C,TBK1,TEX14,TFAP4,TGFA,TLR2,TMEM106A,TRIB2,TRIB3,TXN,UBA52,UBASH3B,USP15,VRK2,WDFY2,XRCC6,YWHAE,ZFP36 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1603 | 1863 | 162 | ADGRG3,ADORA2B,AGO3,ANKRD54,AREG,ARHGAP18,ARHGAP33,ARHGEF1,ATF3,AURKA,BCL10,BOP1,BRPF1,C9orf72,CANT1,CCL20,CCL5,CD14,CD44,CDC34,CIB1,COPS5,CREB3,CRKL,CSNK2A1,CTH,DDIT3,DDX21,DHX36,DNAJC27,DNMBP,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EDA2R,EEF1D,EIF2AK2,EPGN,EPHA2,EREG,EZH2,FAS,FGF8,FHL2,FLT1,GADD45A,GDF15,GOLT1B,GPAT3,HAX1,HBEGF,HERPUD1,HOMER2,HSP90AA1,HSP90AB1,HUS1,IL23A,INHBE,IRAK2,ITPR1,KARS1,KLHDC10,LARS1,LILRA5,LURAP1L,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK3,MCL1,MFHAS1,MSX1,MTDH,MYC,NBN,NET1,NEUROD2,NOP2,NOP53,NPM1,NR1D1,OTUD7A,PAFAH1B1,PAQR3,PDE4D,PDGFA,PELI2,PHF20,PIH1D1,PIM2,PIP4P1,PLK2,PLK3,PMAIP1,PPP2CA,PRKAA1,PRKAB2,PRMT1,PRMT5,PRNP,PRR5,RAC1,RACK1,RAD9A,RAP1B,RELL1,RFFL,RGS4,RHEB,RHNO1,RINT1,RMI2,RPF2,RPL11,RPL23,RPL26,RPL5,RPS27A,RPS3,SEC13,SELENOK,SELENOS,SEMA3A,SESN2,SLIT2,SPATA13,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,SYVN1,TAF1,TAF4,TAF4B,TAF6,TBC1D10C,TBK1,TBP,TFG,TGFA,TLR2,TMBIM6,TMEM106A,TMEM161A,TPT1,TRAP1,TRIB2,TRIB3,TXN,UBA52,UBQLN1,UBR1,URI1,VRK2,WRN,YBX3 |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 987 | 111 | AAAS,ARIH1,ARIH2,ATG7,AURKA,BSCL2,C9orf72,CDC37,CDK4,CNOT1,CNOT7,CSNK1A1,CSNK2A1,DDIT3,DFFA,DHX36,ECD,EEF1A1,EIF6,EXOSC1,FBXL5,FOXF2,GCLC,GNAI3,GTPBP1,HAX1,HDAC4,HERPUD1,HK2,HSP90AA1,HSP90AB1,IDE,IGF2BP3,ITPR1,KAT8,LARS1,LRPPRC,MAPK9,MCL1,MEIOC,METTL16,MTDH,N4BP1,NAMPT,NBAS,NOCT,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,OAZ1,ODC1,PABPC4,PAM16,PDE12,PGAM1,PIM2,PLK2,PLK3,PRKAA1,PRKAB2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,QSOX1,RAB3GAP2,RACK1,RAD23A,RAD23B,RHEB,RMC1,RNF19A,RPL11,RPL23,RPL5,RPS27A,SEC13,SESN2,SMURF2,SPTLC2,SUMO1,TAF1,TARDBP,TBC1D14,TBK1,TENT2,TENT4B,TRIB2,TRIB3,UBA52,UBE2V2,UBQLN1,UPF1,XPO1,YBX1,YBX3,ZFP36 |
| GO_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 229 | 53 | AAAS,ABCE1,BICD1,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DDX19B,DDX39A,DHX36,EIF5A2,EIF6,ENY2,G3BP2,IGF2BP3,LRPPRC,MAGOH,NMD3,NOP10,NOP58,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,PIH1D1,RIOK2,RPS15,RTRAF,RUVBL2,SDAD1,SEC13,SNUPN,SRSF1,SRSF3,SRSF7,TCP1,THOC6,TOMM20,U2AF1,U2AF2,UPF1,UPF3A,WDR33,XPO1,XPO5,XPOT,ZFP36 |
| GO_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 925 | 106 | AEN,APOBEC3A,APOBEC3D,ASF1A,BANF1,BCCIP,CCDC36,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC34,CEBPG,CERS1,CHRAC1,CHTF8,CIB1,COPS5,DFFA,DHX36,DICER1,EZH2,GADD45A,GLRX2,GNL3,H4C2,H4C3,H4C4,HMGA1,HSP90AA1,HSP90AB1,HUS1,LIG3,LONP1,MAP3K4,MAPKAPK5,MEIOC,MMS19,MNAT1,MORF4L2,MTRR,MUTYH,MYC,NBN,NIBAN2,NOP10,NOP53,NPM1,NUDT1,ORC3,ORC4,PAM16,PIWIL2,PLD6,PNKP,POLD2,POLE4,POLR2C,POLR2H,POLR2J,POT1,PPIE,PPM1D,PRDM14,PRIM2,PRIMPOL,PRMT5,PSMD14,PSME4,RAD23A,RAD23B,RAD51B,RAD9A,RHNO1,RMI2,RPS27A,RPS3,RUVBL2,SESN2,SHLD3,SMARCB1,SMPD3,SUMO1,TATDN1,TCEA1,TCP1,TDP1,TENT4B,TFRC,THAP10,TIPIN,TMEM161A,TOP1MT,TSN,UBA52,UBE2V2,UPF1,WDR33,WRN,XRCC6,XRN2,ZNF91,ZRANB3 |
| GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1603 | 68 | 32 | ABT1,BYSL,DCAF13,EMG1,ERAL1,FAM207A,NGDN,NOB1,NOP14,NPM1,RIOK1,RIOK2,RPL38,RPS10,RPS14,RPS15,RPS16,RPS19,RPS21,RPS24,RPS27,RPS28,RPS5,RPS6,RPS8,RPSA,RRP7A,RRP7BP,UTP23,UTP4,UTP6,WDR46 |
| GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1603 | 68 | 31 | BOP1,DDX18,EIF6,GTPBP4,MRPL1,NLE1,NOP2,NOP53,NPM1,RPF2,RPL10,RPL10A,RPL11,RPL12,RPL14,RPL23A,RPL24,RPL26,RPL3,RPL35,RPL35A,RPL38,RPL5,RPL6,RPL7,RPLP0,RPLP0P6,RSL1D1,RSL24D1,SDAD1,SNU13 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1710 | 147 | ABT1,ARF4,ASF1A,ATF3,BCL10,BRPF1,BUD23,BUD31,CASK,CCNC,CDK8,CEBPG,CEBPZ,CEP290,CHCHD2,CNBP,CNOT1,CNOT7,COPS5,CREB3,CREB5,CREM,CXXC1,DDIT3,DHX36,DIMT1,DLX2,E2F6,E2F7,ECD,ELK4,ELOC,EN2,ENY2,ESRRG,ETV4,ETV5,FHL2,FOSB,FOSL1,FOXA2,FOXC2,FOXF2,GABPB1,GABPB2,GATA6,GFI1,GNL3,GPBP1,GTF2B,GTPBP1,HAX1,HDAC4,HES1,HMGA1,HOXA3,IER2,IER5,IL23A,ILF2,ING1,KARS1,KAT2A,KAT8,KLF10,LDB2,LYL1,MAFF,MAP2K1,MARS1,MAX,MED26,METTL16,MMS19,MNAT1,MORF4L2,MSX1,MTDH,MTF1,MYC,MYT1L,NAA15,NAMPT,NEUROD2,NFYA,NIBAN2,NIF3L1,NMD3,NME2,NOLC1,NPM1,NR1D1,NR1D2,NR1H2,NUP98,PCGF6,PELP1,PHF19,PID1,PIH1D1,PIM1,PIM2,PRKAA1,PSMC5,PSRC1,RFX2,RFX3,RGMB,RIOK1,RIOK2,RPS27A,RTRAF,RUNX1,RUVBL2,SESN2,SETD3,SIM2,SMAD5,SMARCB1,SS18L1,TAF1,TAF4,TAF4B,TBK1,TBP,TBX20,TCEA1,TFAP2C,TFAP4,TFB2M,TLR2,U2AF2,UBA52,UPF1,UTP15,WBP2NL,WDR43,WDR77,XRCC6,YBX1,ZC3H8,ZCCHC18,ZFP36,ZIC2,ZNF143,ZNF567,ZNF609 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1470 | 133 | ABCE1,ASF1A,ATF3,BATF3,CBX3,CERS1,CNBP,CNOT1,CNOT7,CREM,CRY1,DDIT3,DDX20,DFFA,DHX36,DICER1,DLX2,DRAP1,E2F6,E2F7,ELK4,EMX2,EREG,ERF,EZH2,FHL2,FOSB,FOXC2,FOXF2,FOXQ1,GATA6,GCLC,GFI1,GON4L,H3C14,H4C2,H4C3,H4C4,HAMP,HDAC4,HES1,HMGA1,KAT8,KLF10,KLF16,LDB2,LRPPRC,MAX,MBD1,MDFI,MEIOC,METTL16,MIER2,MORF4L2,MSX1,MTDH,MTF1,MYC,MYT1L,NBAS,NBN,NEUROD2,NIBAN2,NIF3L1,NOCT,NOP53,NPM1,NR1D1,NR1D2,NR1H2,PAM16,PCGF6,PID1,PLK3,POT1,PPHLN1,PPID,PPM1D,PRDM14,PRMT5,PSMC5,PTBP2,RFX3,RMI2,RNF2,RPL10,RPL23,RPS13,RPS14,RPS27A,RPS3,RUNX1,RUVBL2,SAP130,SAP18,SARS1,SFMBT1,SHLD3,SIAH2,SIM2,SMAD5,SMURF2,SRSF7,SUMO1,TAF1,TARDBP,TBX20,TENT2,TENT4B,TFAP2C,TFAP4,TMBIM6,TRIB3,TRIM11,TRIM33,TXN,U2AF2,UBA52,URI1,UXT,VAX1,XPO1,XRCC6,YBX1,YBX3,ZC3H8,ZFP36,ZIC2,ZNF451,ZNF567,ZNF586,ZNF91,ZRANB3 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1673 | 144 | AGO3,ASF1A,ATF3,ATG7,BATF3,C8orf88,CBX3,CERS1,CNBP,CNOT1,CNOT7,CREM,CRY1,DDIT3,DDX20,DHX36,DICER1,DLX2,DRAP1,E2F6,E2F7,EIF2AK2,EIF2S1,EIF4EBP1,EIF6,ELK4,EMX2,EPRS1,EREG,ERF,ERFE,EZH2,FHL2,FOSB,FOXC2,FOXF2,FOXQ1,GATA6,GCLC,GFI1,GON4L,GTPBP4,H3C14,H4C2,H4C3,H4C4,HAMP,HBEGF,HDAC4,HES1,HMGA1,HUS1,IGF2BP3,IREB2,KAT8,KLF10,KLF16,LDB2,LIG3,MAX,MBD1,MDFI,METTL16,MIER2,MORF4L2,MSX1,MTDH,MTF1,MYC,MYT1L,NEUROD2,NIBAN2,NIF3L1,NOP53,NR1D1,NR1D2,NR1H2,PAIP2,PCGF6,PDGFA,PID1,PLK3,POT1,PPHLN1,PPID,PPM1D,PRDM14,PRKAA1,PRMT5,PSMC5,RACK1,RFX3,RNF2,RPL10,RPL13A,RPL23,RPS14,RPS27A,RPS3,RUNX1,RUVBL2,SAP130,SAP18,SARS1,SELENOS,SESN2,SFMBT1,SIAH2,SIM2,SMAD5,SMPD3,SMURF2,SPHK1,SUMO1,TAF1,TBX20,TENT4B,TFAP2C,TFAP4,TIPIN,TMBIM6,TRAP1,TRIB2,TRIB3,TRIM11,TRIM33,TXN,UBA52,UPF1,URI1,UXT,VAX1,XPO1,XRCC6,YBX1,YBX3,ZC3H8,ZFP36,ZIC2,ZNF451,ZNF567,ZNF586,ZNF91,ZRANB3 |
| GO_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 1223 | 119 | ANAPC5,ANXA1,ASF1A,AURKA,BANF1,BOD1,BRPF1,BUD23,CBX3,CCDC36,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC23,CDC26,CENPN,CHRAC1,CHTF8,COPRS,COPS5,CXXC1,DHX36,ELK4,ENY2,EZH2,FOXA2,G3BP1,GFI1,GNL3,GTF2B,H2AC15,H2AC17,H2AC20,H2AC21,H2BC11,H2BC12,H2BC13,H2BC8,H3C14,H4C2,H4C3,H4C4,HDAC4,HMGA1,HSP90AA1,HSP90AB1,HUS1,JADE3,KAT2A,KAT8,KATNB1,MAP3K4,MAPKAPK5,MBD1,MEIOC,MIER2,MNAT1,MORF4L2,MRGBP,MSTO1,MYC,NAA50,NBN,NOP10,NPM1,NUP98,PCGF6,PELO,PHF19,PHF20,PIH1D1,PIWIL1,PIWIL2,PNKP,POLD2,POLE4,POT1,PPHLN1,PPM1D,PRDM14,PRIM2,PRKAA1,PRMT1,PRMT5,PSME4,PSRC1,RAD23B,RCCD1,RIOK2,RMI2,RNF2,RPS27A,RUVBL2,SETD3,SFMBT1,SGF29,SHCBP1L,SMARCB1,SS18L1,TAF1,TAF6,TCP1,TENT4B,TERB2,TEX14,TOP1MT,UBA52,UPF1,USP15,WRN,XRCC6,ZNF207,ZNF451,ZRANB3,ZW10 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 831 | 95 | ARIH1,ARIH2,ATG7,AURKA,C9orf72,CDC37,CNOT1,CNOT7,CSNK1A1,CSNK2A1,DDIT3,DFFA,DHX36,EEF1A1,EXOSC1,FBXL5,FOXF2,GCLC,GNAI3,GTPBP1,HAX1,HERPUD1,HK2,HSP90AA1,HSP90AB1,IGF2BP3,ITPR1,KAT8,LARS1,LRPPRC,MAPK9,MCL1,MEIOC,METTL16,MTDH,N4BP1,NAMPT,NBAS,NOCT,NOP53,NPM1,PABPC4,PAM16,PDE12,PGAM1,PIM2,PLK2,PLK3,PRKAA1,PRKAB2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,QSOX1,RAB3GAP2,RACK1,RAD23A,RAD23B,RHEB,RMC1,RNF19A,RPL11,RPL23,RPL5,RPS27A,SESN2,SPTLC2,SUMO1,TAF1,TARDBP,TBC1D14,TBK1,TENT2,TENT4B,TRIB2,TRIB3,UBA52,UBE2V2,UBQLN1,UPF1,XPO1,YBX1,YBX3,ZFP36 |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 0.0e+00 | 1603 | 1210 | 117 | ABCE1,AIM2,ANXA1,BOLA2B,CANX,CCL20,CCL5,CD14,CD44,CDC34,CDC37,CDK4,CIB1,CNOT7,CRKL,CTH,CXCL2,CXCL3,DDOST,DUOX2,EDA2R,EIF2AK2,EPRS1,EREG,FOSL1,FOXA2,GBP3,GBP6,GCLC,GCLM,GFI1,GFPT2,H2BC11,H3C14,HAMP,HAX1,HDAC4,HK2,HSP90AA1,HSP90AB1,IFNGR2,IL15RA,IL18BP,IL23A,IL4R,IRAK2,KARS1,KAT2A,MAPKAPK3,MCL1,MT2A,MYC,MYNN,NR1D1,NR1H2,OTULIN,PAFAH1B1,PDE12,PDIA3,PELI2,PFKP,PID1,PIGA,PIM1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PTPN4,RACK1,RAD23B,RAP1B,RFFL,RFX2,RHEX,RNMT,RPL13A,RPL3,RPLP0,RPS2,RPS27A,RPS3,RPS6KB1,RUNX1,SEC61A1,SHMT2,SLIT2,SMPD3,SPATA2,SPHK1,SPRY2,SRSF3,SRSF7,SUMO1,TBK1,TCP1,TEX14,TFRC,TLR2,TNFRSF11B,TRAF3,UBA52,UPF1,VRK2,YBX1,YBX3,ZFP36 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1880 | 153 | ADORA2B,ALG10B,ANKRD54,AREG,ATF3,ATG7,BCAR3,BCCIP,BCL10,BOD1,BORA,C9orf72,CAB39,CCL20,CCL5,CCNC,CCNJ,CD44,CDC37,CDK4,CEP85,CIB1,CNOT7,COPS5,CRKL,CRY1,DERL1,DNAJC27,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EPGN,EPHA2,EREG,EZH2,FAS,FGF8,FLT1,FOXF2,GADD45A,GCLC,GDF15,GFI1,GNL3,GTPBP4,HAX1,HBEGF,HDAC4,HERPUD1,HES1,HSP90AA1,HSP90AB1,HUS1,IL23A,INHBE,IPO5,IRAK2,KARS1,KAT2A,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPK9,MAPKAPK3,MAPKAPK5,MARK2,MFHAS1,MNAT1,MOB2,MYC,N4BP1,NBN,NOP53,NPM1,PAFAH1B1,PAK4,PAQR3,PDE4D,PDGFA,PELI2,PFN2,PHF19,PID1,PIH1D1,PIWIL2,PNKP,PPP1R14B,PPP1R16A,PPP2CA,PPP2R2A,PRKAA1,PRKAR1B,PRMT1,PRMT5,PRNP,PRR5,PRRC1,PSRC1,PUM3,RAB3GAP2,RAC1,RACK1,RAP1B,RELL1,RGS4,RPL11,RPL23,RPL5,RPLP1,RPS2,RPS27A,RPS3,RTRAF,RUVBL2,SEMA3A,SESN2,SIAH2,SLIT2,SMARCB1,SMPD3,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,SVBP,TAF1,TARDBP,TBC1D10C,TBK1,TFAP4,TGFA,TMEM106A,TRIB2,TRIB3,TXN,U2AF2,UBA52,UBASH3B,UBQLN1,URI1,VRK2,WDFY2,XRCC6,YWHAE,ZNF451 |
| GO_MODIFICATION_DEPENDENT_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 642 | 81 | ANAPC5,ARIH1,ARIH2,AURKA,C18orf25,CCDC47,CDC23,CDC26,CDC34,CSNK1A1,CSNK2A1,DDIT3,DERL1,DNAJB9,ELOC,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GID4,HERPUD1,HSP90AB1,KCTD5,KCTD6,KLHL8,LONP1,LTN1,MAPK9,N4BP1,NOP53,OTUD7A,PLK2,PLK3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPL23,RPL5,RPS27A,SEC61B,SEL1L,SELENOS,SIAH2,SMURF2,SUMO1,SYVN1,TAF1,TENT4B,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,USP12,USP15,USP24,USP42,ZFAND2B |
| GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 337 | 58 | AADAT,AARS1,AIMP1,ALDH18A1,ALDH8A1,ASNS,BCAT1,BHMT2,BLMH,CARS1,CTH,DARS1,DLST,EARS2,EPRS1,FARSB,GARS1,GCLC,GCLM,GFPT1,GFPT2,GLYATL1,GPT2,HAAO,HARS1,IARS1,IL4I1,KARS1,LARS1,MARS1,MTR,MTRR,OAZ1,ODC1,PHGDH,PRDX4,PSAT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PYCR1,SARS1,SHMT2,SMS,TARS1,TYR,YARS1 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 1703 | 143 | ADGRG3,ANXA1,ANXA5,AREG,ATF3,ATG7,BICD1,C5orf30,CASK,CCL5,CD14,CD44,CDC34,CHAC1,CIB1,CNOT1,CNOT7,CREB3,CRY1,CSNK1A1,CSNK2A1,CTH,DDIT3,DLX2,DNAJB9,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EMD,ENY2,EPGN,EPHA2,EPS15L1,EREG,EZH2,FAS,FHL2,FOXA2,FSTL4,G3BP1,GCLC,GCLM,GDF15,GNAI3,GPRASP1,GRB10,H2BC11,HBEGF,HERPUD1,HMGXB4,HOMER2,IL4R,ITPR1,KCTD6,MAPKAPK5,MARK3,MCL1,MDFI,MFHAS1,MYC,NAMPT,NBL1,NDUFAF2,NIBAN2,NLE1,NOP53,NR1D1,NR1D2,NR1H2,OTUD7A,OTULIN,PAFAH1B1,PAM16,PAQR3,PDE4D,PDGFA,PID1,PIH1D1,PLK2,PPP2CA,PRDM14,PRKAA1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PYCR1,RACK1,RFFL,RFX8,RGS17,RGS4,RGS5,RMI2,RPS19,RPS27A,RPS3,RPS6KB1,RUVBL2,SELENOS,SEMA3A,SESN2,SGK3,SHLD3,SIAH2,SLIT2,SMURF2,SOCS7,SPRED1,SPRED2,SPRY2,SPRY4,SYVN1,TBC1D10C,TBX20,TGFA,TMBIM6,TMEM161A,TPT1,TRAP1,TRIB3,TRIM33,TXN,UBA52,UBASH3B,UBQLN1,UBR1,URI1,YBX3,ZNF451 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1724 | 144 | ADORA2B,AIM2,ALG10B,AREG,ARIH1,ARIH2,ATG7,AURKA,BCAR3,BCL10,BLID,BORA,CAB39,CCL20,CCL5,CD44,CDC123,CDK4,CEBPG,CIB1,CLPX,CNBP,CRKL,CRY1,CSNK1A1,CSNK2A1,DERL1,DHX36,DNAJC27,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EIF2S3,EIF3C,EIF3D,EIF5A2,EIF6,EPGN,EREG,EZH2,FAS,FBXL5,FGF8,FLT1,GADD45A,GCLC,GDF15,GNL3,HAX1,HBEGF,HDAC4,HERPUD1,HES1,HSP90AA1,HSP90AB1,IDE,IL23A,INHBE,IRAK2,KARS1,KAT2A,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPK9,MAPKAPK3,MAPKAPK5,MARK2,MFHAS1,MNAT1,MOB2,MYC,NBN,NOP53,NPM1,NR1H2,NSUN4,OAZ1,PAK4,PDCD2,PDCD5,PDGFA,PELI2,PFN2,PHF19,PIH1D1,PIWIL2,PLK2,PLK3,PMAIP1,PPP2CA,PRKAA1,PRKAR1B,PRMT1,PRNP,PRR5,PRRC1,PSMD14,PSME4,PSRC1,RAB3GAP2,RAC1,RACK1,RAD23A,RAP1B,RELL1,RNF19A,RPL26,RPL30,RPL5,RPLP1,RPS2,RPS27A,RPS3,RPS4X,RPS6KB1,RPS9,RUVBL2,SEMA3A,SERP1,SMARCB1,SMURF2,SPHK1,SPRY2,SUMO1,TAF1,TBK1,TFAP4,TGFA,TMEM106A,TRIB2,TRIB3,TXN,UBA52,UBE2V2,UBQLN1,UPF3A,WDFY2,XRCC6,YBX3 |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1603 | 1427 | 128 | ADGRG3,ANXA5,AP1AR,AREG,ATF3,BICD1,CCL5,CD14,CD44,CDC34,CHAC1,CIB1,CNOT1,CNOT7,CREB3,CRY1,CSNK1A1,CSNK2A1,CTH,DDIT3,DLX2,DNAJB9,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EMD,ENY2,EPGN,EPHA2,EPS15L1,EREG,EZH2,FAS,FHL2,FSTL4,G3BP1,GCLC,GCLM,GDF15,GNAI3,GPRASP1,GRB10,H2BC11,HBEGF,HERPUD1,HMGXB4,HOMER2,ITPR1,KCTD6,MAPKAPK5,MARK3,MCL1,MDFI,MFHAS1,MYC,NBL1,NDUFAF2,NIBAN2,NLE1,NOP53,NR1D1,NR1H2,OTUD7A,PAFAH1B1,PAM16,PAQR3,PDE4D,PID1,PIH1D1,PLK2,PPP2CA,PRDM14,PRKAA1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAP1B,RFFL,RFX8,RGS17,RGS4,RGS5,RPS27A,RPS6KB1,RUVBL2,SELENOS,SESN2,SGK3,SIAH2,SLIT2,SMURF2,SOCS7,SPRED1,SPRED2,SPRY2,SPRY4,SYVN1,TBC1D10C,TBX20,TGFA,TMBIM6,TMEM161A,TPT1,TRAP1,TRIB3,TRIM33,UBA52,UBASH3B,UBQLN1,UBR1,URI1,YBX3,ZNF451 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1301 | 120 | AADAT,ACOT7,ADAMTS9,ALDH8A1,ANAPC5,APOBEC3A,APOBEC3D,ARIH1,ARIH2,ATG7,AURKA,BCAT1,BLMH,C18orf25,CCDC47,CD44,CDC23,CDC26,CDC34,CHAC1,CHDH,CLPX,CSNK1A1,CSNK2A1,CTH,DDIT3,DERL1,DLST,DNAJB9,EEF1A1,ELOC,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,GPC6,GPT2,HAAO,HERPUD1,HSP90AA1,HSP90AB1,IDE,IL4I1,KCTD5,KCTD6,KLHL8,LONP1,LTN1,MAPK9,MTRR,N4BP1,NGLY1,NOP53,NR1D1,NT5C,NUDT1,OAZ1,ODC1,OTUD7A,PDCD6IP,PDE4D,PDXP,PLK2,PLK3,PMAIP1,PNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPL23,RPL5,RPS27A,SEC61B,SEL1L,SELENOS,SHMT2,SIAH2,SMPD3,SMURF2,SPHK1,SUMO1,SYVN1,TAF1,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,USP12,USP15,USP24,USP42,XPO1,YME1L1,ZFAND2B |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 782 | 89 | ANAPC5,ARIH1,ARIH2,AURKA,C18orf25,CCDC47,CDC23,CDC26,CDC34,CLPX,CSNK1A1,CSNK2A1,DDIT3,DERL1,DNAJB9,ELOC,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,HERPUD1,HSP90AA1,HSP90AB1,IDE,KCTD5,KCTD6,KLHL8,LONP1,LTN1,MAPK9,N4BP1,NGLY1,NOP53,NR1D1,OTUD7A,PDCD6IP,PLK2,PLK3,PMAIP1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPL23,RPL5,RPS27A,SEC61B,SEL1L,SELENOS,SIAH2,SMURF2,SUMO1,SYVN1,TAF1,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,USP12,USP15,USP24,USP42,YME1L1,ZFAND2B |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 1235 | 116 | AAAS,AEN,ANXA1,ANXA7,APOLD1,ASNS,ATG7,BCL10,BRSK1,CAB39,CACNA1F,CCDC66,CD14,CDK4,CERS1,CHCHD2,CLPB,CRY1,DHX36,EEF1D,EIF2B2,EIF2S1,EIF4EBP1,ELOC,FAS,FNTB,FOSB,FOSL1,GADD45A,GATA6,GCLC,GLRX2,HAMP,HDAC4,HK2,HRH1,HSP90AA1,HSP90AB1,HSP90AB3P,HSPA13,HUS1,IER5,IKBIP,ITPR1,KARS1,LONP1,MAP3K4,MTCO2P12,MYC,N4BP1,NAMPT,NET1,NETO1,NEUROD2,NMT1,NOLC1,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,PKD2L2,PLK3,PMAIP1,PNKP,PPID,PPM1D,PRIMPOL,PRKAA1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RAD9A,RHNO1,RP1,RPL26,RPS27A,RPS6KB1,RUVBL2,SEC13,SLC1A2,STAC,STC2,SUMO1,TAF1,TBL2,TENT2,TIPIN,TLR2,TMBIM6,TMC2,TMEM161A,TNC,TXN,TYR,UBA52,UBQLN1,WRN,XRCC6,YBX3,YWHAE,ZRANB3 |
| GO_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 835 | 92 | AAAS,ABCC4,ABT1,ACRBP,ARL13B,ATG16L1,ATG7,AURKA,BBIP1,BCCIP,BICD1,BOP1,C10orf90,C5orf30,C9orf72,CCDC66,CCSAP,CENPN,CEP290,CEP97,CFAP74,CNOT1,CNOT7,DYNC2LI1,EDC3,EFL1,EIF2S1,EIF6,ERAL1,G3BP1,G3BP2,HSP90AA1,KAT2A,MAPK9,MAPRE1,MKS1,MRPL22,MSTO1,NEDD1,NLE1,NOCT,NOP2,NOP53,NPM1,NSUN4,PAFAH1B1,PDCD6IP,PLK2,POC1B,PRKAA1,RAB3GAP2,RFX2,RFX3,RP1,RPF2,RPGR,RPL10,RPL11,RPL12,RPL23A,RPL24,RPL3,RPL38,RPL5,RPL6,RPLP0,RPLP0P6,RPS10,RPS14,RPS15,RPS19,RPS23,RPS27,RPS28,RPS3,RPS5,RPSA,RRP7A,RRP7BP,RSL24D1,RTTN,SPAG1,SSNA1,TBC1D14,TMEM216,TMOD3,UBQLN1,VTA1,WBP2NL,YWHAE,ZMYND10,ZNF207 |
| GO_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 790 | 89 | ADAMTS1,ANAPC5,ANXA1,AURKA,BORA,BRSK1,C10orf90,CBX3,CCDC36,CCSAP,CDC23,CDC26,CDK4,CEP290,CEP85,CEP97,CNOT1,CNOT7,CSNK2A1,E2F6,E2F7,ECD,EPGN,EREG,EVI2B,EZH2,FBXO43,FGF8,GADD45A,GATA6,GPR3,HSP90AA1,HSP90AB1,HUS1,KAT2A,MAPRE1,MAX,MSX1,NBN,NEDD1,NOP53,NPM1,NUBP1,PAFAH1B1,PCGF6,PDCD6IP,PDXP,PIWIL2,PLK2,PLK3,PLRG1,PRMT1,PRMT5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RAD51B,RHNO1,RINT1,RIOK2,RMI2,RNF2,RPL23,RPL26,SMPD3,SSNA1,TAF1,TEX14,TFAP4,TGFA,TIPIN,TMOD3,UXT,XPO1,YWHAE,ZNF207,ZW10 |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1603 | 1625 | 136 | AAAS,ADORA2B,ANKRD54,AREG,ATF3,BCAR3,BCCIP,BCL10,BORA,C9orf72,CAB39,CCL20,CCL5,CCNC,CCNJ,CD44,CDC37,CDK4,CEP85,CIB1,CNOT7,COPS5,CRKL,DNAJC27,DUSP12,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,ECD,EDA2R,EEF1A1,EIF2AK2,EIF6,EPGN,EPHA2,EREG,EZH2,FAS,FGF8,FLT1,FOXA2,GADD45A,GDF15,GTPBP4,HAX1,HBEGF,HDAC4,HES1,HSP90AA1,HSP90AB1,HUS1,IL23A,INHBE,IPO5,IRAK2,KARS1,KLHDC10,LDB2,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MFHAS1,MNAT1,MOB2,MYC,NBN,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,PAFAH1B1,PAK4,PAQR3,PDE12,PDE4D,PDGFA,PELI2,PFN2,PGAM1,PID1,PIH1D1,PPP1R14B,PPP2CA,PRKAA1,PRKAR1B,PRMT1,PRMT5,PRNP,PRR5,PRRC1,PSRC1,RAC1,RACK1,RAP1B,RELL1,RGS4,RPLP1,RPS27A,RPS3,RTRAF,SEC13,SEMA3A,SESN2,SHMT2,SLIT2,SMPD3,SOCS7,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,TARDBP,TBC1D10C,TBK1,TFAP4,TGFA,TMEM106A,TRIB2,TRIB3,TXN,UBA52,UBASH3B,VRK2,WDFY2,XRCC6 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1603 | 1748 | 142 | AARS1,AMIGO2,ANXA1,ANXA5,ARF4,ARHGEF1,ASNS,ATF3,ATG7,AURKA,BCL10,BLID,CCL5,CD44,CDC34,CDK4,CFDP1,CIB1,COPS5,CREB3,CSNK2A1,CTH,CTNNBL1,DDIT3,DDX20,DFFA,DUSP6,EIF2AK2,EIF2S1,EN2,EVI2B,FAS,FBXO10,FGF8,FHL2,FOSL1,FOXC2,FOXQ1,GADD45A,GATA6,GCLC,GCLM,GDF15,GLO1,GNAI3,HAX1,HDAC4,HERPUD1,HSP90AB1,ING1,INHBE,KATNB1,MAPK9,MCL1,MNAT1,MSX1,MTCO2P12,MTDH,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,MYC,NAA15,NET1,NIBAN2,NLE1,NME2,NMT1,NOP53,NPM1,OSGIN1,PAK4,PAM16,PDCD2,PDCD5,PDE12,PDIA3,PHLDA1,PIH1D1,PIM1,PIM2,PLK2,PLK3,PMAIP1,PPID,PRKAA1,PRNP,PSMC5,PTRH2,PYCR1,RACK1,RAD9A,RFFL,RILPL1,RPL10,RPL11,RPL26,RPS27A,RPS3,RPS3A,RPS6,RPS6KB1,RSL1D1,SAP18,SELENOS,SGK3,SIAH2,SLIT2,SPATA2,SPHK1,SPRY2,STK40,SYVN1,TARDBP,TBK1,TCP1,TFAP4,THOC6,TMBIM6,TMEM161A,TPT1,TRAF3,TRAP1,TXN,TXNDC5,UBA52,UBE2V2,UBQLN1,UFM1,URI1,USP42,WRN,YBX3,YME1L1,YWHAE,ZC3H8,ZFP36 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 1267 | 116 | ABI2,ANAPC5,ANKRD27,ANXA1,AP1AR,ARHGAP18,ARIH2,ARPC5L,ASF1A,AURKA,BAIAP2L2,BICD1,BORA,C10orf90,C9orf72,CARMIL2,CCDC36,CCSAP,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC23,CDC26,CDC37,CEP85,CEP97,CIB1,CNOT1,COTL1,DHX36,DYNC2LI1,EPGN,EREG,FBXO43,FGF8,G3BP1,G3BP2,GCLC,GFI1,GNL3,GPR3,HAX1,HK2,HMGA1,KAT2A,KATNB1,KATNBL1,LMAN1,MAP2K1,MAP3K4,MAPK9,MAPKAPK5,MAPRE1,MARK2,MNAT1,MSX1,MYC,NAV3,NBN,NMT1,NPM1,NUBP1,PAFAH1B1,PAM16,PDCD5,PDCD6IP,PDGFA,PDXP,PFDN2,PFN2,PHF19,PID1,PIH1D1,PIWIL2,PLD6,PLK2,PMAIP1,PNKP,POT1,PPFIA1,PPHLN1,PRKAA1,PRMT5,PSRC1,RAB3GAP2,RAC1,RGS4,RIOK2,RMI2,RP1,RPS3,RUVBL2,SHCBP1L,SLIT2,SMARCB1,SMPD3,SPHK1,TBC1D14,TCP1,TENT4B,TEX14,TGFA,TMED9,TMOD3,TRIM36,UPF1,XPO1,YWHAE,ZMYND10,ZNF207,ZNF451,ZW10 |
| GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 484 | 67 | AARS1,AGO3,C8orf88,CCL5,CDC123,CDK4,CNBP,CNOT1,CNOT7,DHX36,DPH3,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF2S3,EIF3C,EIF3D,EIF3K,EIF4EBP1,EIF4H,EIF5A2,EIF6,EPRS1,ETF1,GTPBP2,IGF2BP3,IREB2,LRPPRC,LTN1,MAGOH,MAPKAPK5,METTL16,NGDN,NOLC1,NPM1,NSUN4,PAIP2,PGAM1,PIWIL1,PIWIL2,PRKAA1,PRNP,RACK1,RPL10,RPL13A,RPL26,RPL30,RPL38,RPL5,RPLP1,RPS14,RPS3,RPS4X,RPS6KB1,RPS9,SERP1,SESN2,SHMT2,SMPD3,SPHK1,TRAP1,UPF1,UPF3A,YBX3,ZFP36 |
| GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 478 | 66 | ANAPC5,ARIH1,ARIH2,AURKA,CCDC47,CDC23,CDC26,CDC34,CSNK1A1,DDIT3,DERL1,DNAJB9,FBXL5,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,HERPUD1,HSP90AB1,KCTD5,LTN1,MAPK9,N4BP1,NOP53,NR1D1,PLK2,PLK3,PMAIP1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPS27A,SEC61B,SEL1L,SELENOS,SIAH2,SMURF2,SUMO1,SYVN1,TAF1,TRIB2,TRIB3,UBA52,UBE2V2,UBQLN1,UBR1,ZFAND2B |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1823 | 144 | AAAS,ADORA2B,ANKRD54,AREG,ATF3,BCAR3,BCCIP,BCL10,BOD1,BORA,C9orf72,CAB39,CCL20,CCL5,CCNC,CCNJ,CD44,CDC37,CDK4,CEP85,CIB1,CNOT7,CNST,COPS5,CRKL,DNAJC27,DUSP12,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,ECD,EDA2R,EEF1A1,EIF2AK2,EIF6,EPGN,EPHA2,EREG,EZH2,FAS,FGF8,FLT1,FOXA2,GADD45A,GDF15,GTPBP4,HAX1,HBEGF,HDAC4,HES1,HRH1,HSP90AA1,HSP90AB1,HUS1,IL23A,INHBE,IPO5,IRAK2,KARS1,KLHDC10,LDB2,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MFHAS1,MNAT1,MOB2,MTCO2P12,MYC,NBN,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,PAFAH1B1,PAK4,PAQR3,PDE12,PDE4D,PDGFA,PELI2,PFN2,PGAM1,PID1,PIH1D1,PPP1R14B,PPP1R16A,PPP2CA,PPP2R2A,PRKAA1,PRKAR1B,PRMT1,PRMT5,PRNP,PRR5,PRRC1,PSRC1,RAC1,RACK1,RAP1B,RELL1,RGS4,RPLP1,RPS27A,RPS3,RTRAF,SEC13,SEMA3A,SESN2,SHMT2,SLIT2,SMPD3,SOCS7,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,TARDBP,TBC1D10C,TBK1,TFAP4,TGFA,TMEM106A,TRIB2,TRIB3,TXN,UBA52,UBASH3B,URI1,VRK2,WDFY2,XRCC6,YWHAE |
| GO_TRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 183 | 41 | AARS1,AIMP1,C2orf49,CARS1,CTU1,DARS1,DPH3,DUS4L,EARS2,ELP2,EPRS1,FARSB,GARS1,HARS1,IARS1,KARS1,LARS1,MARS1,METTL1,METTL2A,MTO1,PSTK,PUSL1,QTRT1,QTRT2,RPP30,RPP40,RTCB,RTRAF,SARS1,SLFN13,TARS1,THG1L,THUMPD3,TRIT1,TRMO,TRMT61A,TRNT1,TYW1B,TYW5,YARS1 |
| GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 664 | 78 | ADAMTS1,ANAPC5,ANXA1,ASNS,AURKA,BORA,BRSK1,BTG3,CCSAP,CDC23,CDC26,CDK4,CEP290,CEP85,CEP97,CNOT1,CNOT7,E2F7,ECD,EIF4EBP1,EPGN,EREG,EZH2,FGF8,GADD45A,GADD45GIP1,HES1,HSP90AA1,HUS1,INTS13,MAPRE1,MEIOC,NBN,NEDD1,NLE1,NOP53,PAFAH1B1,PDXP,PIM2,PLK2,PLK3,PLRG1,PRMT1,PRMT5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PSRC1,RAD51B,RAD9A,RINT1,RIOK2,RPL24,RPL26,RPS6,RPS6KB1,SMPD3,SPHK1,SSNA1,TEX14,TFAP4,TGFA,TIPIN,TMOD3,YWHAE,ZNF207,ZW10 |
| GO_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 938 | 95 | ADAMTS9,ANAPC5,ARIH1,ARIH2,ATG7,AURKA,C18orf25,CCDC47,CDC23,CDC26,CDC34,CLPX,CSNK1A1,CSNK2A1,DDIT3,DERL1,DNAJB9,EEF1A1,ELOC,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,HERPUD1,HSP90AA1,HSP90AB1,IDE,KCTD5,KCTD6,KLHL8,LONP1,LTN1,MAPK9,N4BP1,NGLY1,NOP53,NR1D1,OAZ1,ODC1,OTUD7A,PDCD6IP,PLK2,PLK3,PMAIP1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPL23,RPL5,RPS27A,SEC61B,SEL1L,SELENOS,SIAH2,SMURF2,SUMO1,SYVN1,TAF1,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,USP12,USP15,USP24,USP42,XPO1,YME1L1,ZFAND2B |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1603 | 1781 | 141 | ADORA2B,AGAP7P,AGAP9,AHSA1,AIM2,ALG10B,ANKRD27,ARF4,ARFGAP3,ARHGAP18,ARHGAP33,ARHGEF1,ARL1,BCL10,BLID,BORA,BUD31,CAB39,CCL20,CCL5,CCT2,CCT4,CEBPG,CHTF8,CIB1,CLPX,COPS5,CRACR2A,CRKL,CTH,DDIT3,DERL1,DOCK5,DPH3,DUSP12,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EIF2S1,EIF3C,EIF3D,EPB41,EPGN,EPHA2,EREG,EZH2,FAS,FLT1,FOSL1,GADD45A,GCLM,GDF15,GNAI3,GTF2B,HDAC4,HES1,HOXA3,HSP90AA1,HSP90AB1,IL23A,IRAK2,KARS1,LARS1,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MAPRE1,MARK2,MARK3,MNAT1,MTDH,MYC,NBN,NET1,NEUROD2,NIBAN2,NMD3,NPM1,NR1H2,NUS1,PAK4,PDCD2,PDCD5,PDGFA,PFN2,PIH1D1,PITRM1,PLK2,PMAIP1,PNKP,POT1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,PSMA6,PSMD14,PSME4,PSRC1,RAB3GAP2,RACK1,RAP1GDS1,RAPGEF6,RGPD5,RGS17,RGS4,RGS5,RHEBL1,RPL11,RPLP1,RPS2,RPS27A,RPS3,RWDD1,SEC23A,SMARCB1,SPHK1,SPRY2,STAC,SUMO1,TAF1,TBC1D10C,TBC1D14,TCEA1,TCP1,TFAP4,TGFA,TLR2,TRIB3,TXN,UBA52,WRN,XRCC6,ZIC2 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1164 | 108 | AAAS,AADAT,AARS1,ABCB11,ABCG2,ABHD10,ACOT7,AIMP1,ALDH18A1,ALDH8A1,ANXA1,ASNS,B4GALT3,BCAT1,BHMT2,BLMH,BPGM,CARS1,CD44,CREM,CTH,CYP2C19,DARS1,DLST,DSE,EARS2,ECD,EIF6,EPRS1,ERFE,FARSB,GARS1,GCLC,GCLM,GFPT1,GFPT2,GLO1,GLYATL1,GLYATL2,GNPDA1,GNPDA2,GPT2,HAAO,HACL1,HARS1,HDAC4,HK2,IARS1,IL4I1,IMPAD1,IREB2,KARS1,LARS1,LIAS,MARS1,MTHFD1L,MTHFD2,MTR,MTRR,NR1D1,NR1H2,NUP54,NUP58,NUP88,NUP93,NUP98,OAZ1,ODC1,PFKP,PGAM1,PHGDH,PIM1,PNP,PON3,PRDX4,PRKAA1,PRKAB2,PSAT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PYCR1,SARS1,SEC13,SESN2,SHMT2,SLC16A1,SLC35D2,SMPD3,SMS,ST3GAL4,TARS1,TLR2,TRIB3,TYR,UEVLD,YARS1 |
| GO_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1603 | 637 | 76 | ADAMTS1,ANAPC5,ANXA1,AURKA,BCAT1,BORA,BRSK1,CCNJ,CDC23,CDC26,CDC34,CDK4,CEP290,CNOT1,CNOT7,E2F6,E2F7,ECD,EIF4EBP1,EZH2,GADD45A,GFI1,HSP90AA1,HUS1,MAPRE1,MAX,MNAT1,MYC,NBN,NEDD1,NOP53,NPM1,ORC3,ORC4,PAFAH1B1,PHLDA1,PIM2,PLK2,PLK3,PLRG1,POLE4,PPM1D,PPP2R2A,PRIM2,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD51B,RINT1,RIOK2,RPL24,RPL26,RPS6,RPS6KB1,SSNA1,TAF1,TEX14,TFAP4,TIPIN,TMOD3,UPF1,YWHAE,ZNF207,ZW10 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1603 | 1779 | 138 | ADAMTS1,ADAMTS9,AGBL3,AIM2,ANAPC5,ARIH1,ARIH2,AURKA,BCL10,BLID,BLMH,C18orf25,CAPN15,CCDC47,CD44,CDC23,CDC26,CDC34,CHAC1,CLPX,COPS5,CSNK1A1,CSNK2A1,DDIT3,DERL1,DNAJB9,DNPEP,ELOC,ENY2,EPPIN,FAS,FBXL5,FBXO10,FBXO38,FBXO48,FOXF2,GCLC,GET4,GID4,HERPUD1,HSP90AB1,IDE,KARS1,KAT2A,KCTD5,KCTD6,KLHL8,LAP3,LONP1,LPAL2,LTN1,MAPK9,MASP2,MYC,N4BP1,NGLY1,NLE1,NLN,NOP53,NR1D1,NR1H2,NUP98,OTUD7A,OTULIN,PDCD2,PDCD5,PDCD6IP,PDIA3,PIH1D1,PITRM1,PLK2,PLK3,PMAIP1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPL23,RPL5,RPS27A,RPS3,SEC61B,SEL1L,SELENOS,SERPINB5,SERPINI2,SHMT2,SIAH2,SMURF2,SPATA2,STAMBPL1,SUMO1,SVBP,SYVN1,TAF1,TFAP4,THSD4,TMEM208,TMEM98,TMPRSS12,TOMM20,TPP2,TRAF3,TRIB2,TRIB3,UBA52,UBE2D2,UBE2G1,UBE2V2,UBQLN1,UBR1,UCHL3,UFSP2,USP12,USP15,USP24,USP39,USP42,YME1L1,YWHAE,ZFAND2B |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1603 | 1559 | 125 | AAAS,ABCE1,ADORA2B,AIM2,ANXA1,ANXA5,ATG7,BCL10,C5orf30,CASK,CCL5,CD14,CD44,CDC37,CEBPG,CHCHD2,CNOT7,COPS5,CREB3,CRY1,DDIT3,DMBT1,DNAJB9,DUOX2,EDA2R,EIF2AK2,EREG,FAS,FOXA2,FOXC2,GADD45A,GFI1,HBEGF,HERPUD1,HMGA1,HSP90AA1,HSP90AB1,ICAM3,IER5,IFNGR2,IL23A,IRAK2,KARS1,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MCL1,MFHAS1,MMS19,MSX1,MYC,NAMPT,NOP53,NPM1,NR1D1,NR1D2,NR1H2,NUP54,NUP58,NUP88,NUP93,NUP98,OTULIN,PAFAH1B1,PDGFA,PLK2,PMAIP1,POLR3D,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,PYCR1,RACK1,RAD9A,RELL1,RINT1,RMI2,RPL26,RPS19,RPS27A,RPS3,RSL1D1,SEC13,SELENOK,SELENOS,SEMA3A,SESN2,SHLD3,SPATA2,SPHK1,SPRED1,SPRED2,SUMO1,SYVN1,TBK1,TLR2,TMBIM6,TMEM161A,TPT1,TRAF3,TRAP1,TXN,UBA52,UBASH3B,UBE2D2,UBE2V2,UBQLN1,XRCC6,YBX3,YWHAE |
| GO_PROTEIN_FOLDING | 0.0e+00 | 0.0e+00 | 1603 | 220 | 42 | CANX,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC37,CLPX,CSNK2A1,DERL1,DFFA,DNAJC25,DNLZ,ERP44,GAK,GNAI3,HSP90AA1,HSP90AB1,HSP90AB3P,HSPA13,LMAN1,NGLY1,NUDC,PDCD5,PDIA3,PDIA6,PDRG1,PFDN2,PPID,PPIE,PPIL3,PRDX4,RAD23B,RUVBL2,SACS,SELENOF,SPHK1,TBCA,TCP1,TRAP1 |
| GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1603 | 267 | 46 | AEN,AURKA,BOP1,BRPF1,CD44,CNOT1,CNOT7,CSNK2A1,E2F7,EDA2R,GADD45A,HUS1,MAPKAPK5,MSX1,NBN,NOP2,NOP53,NPM1,PHF20,PLK2,PLK3,PMAIP1,PPM1D,PRKAA1,PRKAB2,PRMT1,PRMT5,RAD9A,RFFL,RHNO1,RMI2,RPF2,RPL11,RPL23,RPL26,RPL5,SESN2,SPRED1,SPRED2,TAF1,TAF4,TAF4B,TAF6,TBP,TFAP4,WRN |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1603 | 1258 | 108 | AAAS,ABI2,AGBL3,AREG,AURKA,BCAR3,BRPF1,CAB39,CCL5,CD44,CNOT7,COPRS,CSNK1A1,CSNK1G3,CSNK2A1,CTH,CXXC1,DDOST,DOHH,DPH3,DPM1,DPM2,EEF1AKMT4,EIF2AK2,EPGN,EPHA2,EREG,EZH2,FGF8,FKBP11,FKBP14,FLT1,GFI1,GNL3,GTF2B,HAX1,HBEGF,HDAC4,HES1,HSP90AA1,HSP90AB1,IL23A,JADE3,KAT2A,KAT8,LIAS,LILRA5,LMAN1,MAP2K1,MAPK9,MAPKAPK3,MAPKAPK5,MARK2,MARK3,MCFD2,MORC3,MORF4L2,MRGBP,NAA15,NAA50,NDUFAF7,NME2,NMT1,NUP54,NUP58,NUP88,NUP93,NUP98,PAQR3,PDE4D,PDGFA,PFN2,PHF19,PHF20,PIH1D1,PIWIL2,PLK2,POLE4,PPID,PPIE,PPIL3,PPP2CA,PRDM14,PRKAA1,PRMT1,PRMT5,PRNP,RACK1,RPN1,RPS6KB1,RUVBL2,SETD3,SGF29,SGK3,SMARCB1,SPHK1,SPRED1,SPRED2,SPRY2,SUMO1,SYVN1,TAF1,TBK1,TGFA,TXN,VCPKMT,VRK2,ZNF451 |
| GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 240 | 43 | AAAS,ABCE1,DDX19B,DDX39A,EIF5A2,EIF6,ENY2,G3BP2,IGF2BP3,LRPPRC,MAGOH,NMD3,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,RIOK2,RPS15,RTRAF,SDAD1,SEC13,SLC25A6,SLC35A2,SLC35A3,SLC35D2,SNUPN,SRSF1,SRSF3,SRSF7,THOC6,TOMM20,U2AF1,U2AF2,UPF1,UPF3A,WDR33,XPO1,XPO5,XPOT,ZFP36 |
| GO_TRANSLATIONAL_ELONGATION | 0.0e+00 | 0.0e+00 | 1603 | 135 | 33 | AARS1,DAP3,DPH3,EEF1A1,EEF1D,EEF1G,EFL1,EIF5A2,ERAL1,GADD45GIP1,GTPBP1,GTPBP2,HBS1L,LTN1,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,RACK1,RPL30,RPLP1,RPLP2,TUFM |
| GO_ESTABLISHMENT_OF_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 196 | 39 | AAAS,ABCE1,DDX19B,DDX39A,EIF5A2,EIF6,ENY2,G3BP2,IGF2BP3,LRPPRC,MAGOH,NMD3,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,RIOK2,RPS15,RTRAF,SDAD1,SEC13,SNUPN,SRSF1,SRSF3,SRSF7,THOC6,TOMM20,U2AF1,U2AF2,UPF1,UPF3A,WDR33,XPO1,XPO5,XPOT,ZFP36 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 1220 | 105 | ABI2,AIM2,AMIGO2,ANAPC5,ANKRD27,ANXA1,AP1AR,ARIH2,ARPC5L,AURKA,BAIAP2L2,BICD1,CARMIL2,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD14,CDC34,CDC37,CDH4,CIB1,CLDN19,CNOT1,CPNE5,CRKL,DHX36,DOCK5,EIF5A2,EPGN,EPHA2,EREG,EZH2,FBXO38,FGF8,G3BP1,G3BP2,GDF15,GNL3,GOLGA4,HAX1,HDAC4,HK2,HSP90AA1,IDE,IL4R,KAT2A,KATNB1,KATNBL1,LMAN1,MAP2K1,MAP3K4,MAPK9,MAPKAPK5,MAPRE1,MARK2,MOB2,MSX1,NAV3,NBN,NEUROD2,NME2,NMT1,NPM1,NR1H2,PAFAH1B1,PDCD5,PDCD6IP,PDXP,PFDN2,PFN2,PHF19,PIH1D1,PIWIL2,PLD6,PLEK2,PMAIP1,PNKP,POT1,PPHLN1,PRKAA1,PSMC5,PSRC1,RAB3GAP2,RAC1,RACK1,RAP1B,RP1,RPS3,RUVBL2,SHCBP1L,SLIT2,SMARCB1,SMPD3,SS18L1,SUMO1,TCP1,TGFA,TMED9,UBE2V2,YWHAE,ZMYND10 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1280 | 108 | ASF1A,ATF3,BATF3,CBX3,CNBP,CNOT1,CNOT7,CREM,CRY1,DDIT3,DDX20,DICER1,DLX2,DRAP1,E2F6,E2F7,ELK4,EMX2,EREG,ERF,EZH2,FHL2,FOSB,FOXC2,FOXF2,FOXQ1,GATA6,GCLC,GFI1,GON4L,H3C14,H4C2,H4C3,H4C4,HAMP,HDAC4,HES1,HMGA1,KAT8,KLF10,KLF16,LDB2,MAX,MBD1,MDFI,MIER2,MORF4L2,MSX1,MTDH,MTF1,MYC,MYT1L,NEUROD2,NIBAN2,NIF3L1,NOP53,NR1D1,NR1D2,NR1H2,PCGF6,PLK3,PPHLN1,PPID,PPM1D,PRDM14,PRMT5,PSMC5,RFX3,RNF2,RPL10,RPL23,RPS14,RPS27A,RUNX1,RUVBL2,SAP130,SAP18,SARS1,SFMBT1,SIAH2,SIM2,SMAD5,SMURF2,SUMO1,TAF1,TBX20,TFAP2C,TFAP4,TMBIM6,TRIB3,TRIM11,TRIM33,TXN,UBA52,URI1,UXT,VAX1,XPO1,XRCC6,YBX1,YBX3,ZC3H8,ZFP36,ZIC2,ZNF451,ZNF567,ZNF586,ZNF91 |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 622 | 70 | ABCE1,ADORA2B,AP1AR,AP3M2,AP3S2,AREG,ARFGAP3,AURKA,BCCIP,BICD1,BOD1,BRSK1,C17orf75,CDC23,CEP290,CEP97,DYNC1LI2,EIF6,GOSR2,HSP90AA1,IL4R,INTS13,KAT2A,KATNB1,LMAN1,LRPPRC,MAPRE1,MARK2,MCFD2,MEIOC,MKS1,MREG,MSTO1,NEDD1,NMD3,NPM1,NUBP1,NUP88,NUP98,PAFAH1B1,PIP4P1,PSRC1,RAB27A,RAB27B,RABEPK,RIOK2,RPS15,SAPCD2,SDAD1,SEC13,SEC23A,SEC24A,SEC24D,SNAP25,SPOUT1,SPRY2,SSNA1,STARD3NL,STX19,SYNE3,TERB2,TFG,TGFA,TMED9,TMEM216,TRAPPC6B,UXT,XPO1,YWHAE,ZW10 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 976 | 91 | ADORA2B,ANKRD54,BCCIP,BCL10,BORA,CAB39,CCL5,CCNC,CCNJ,CCT2,CCT4,CDC37,CDK4,CEP85,CERS1,CHTF8,CIB1,CRKL,DUSP12,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EEF1A1,EIF2AK2,EPGN,EREG,EZH2,FLT1,FOXA2,GADD45A,GDF15,GTPBP4,HSP90AA1,HSP90AB1,IL23A,IPO5,IRAK2,KARS1,LDB2,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MNAT1,MYC,NBN,NPM1,PAK4,PAQR3,PDGFA,PIH1D1,PNKP,POT1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,PSRC1,RACK1,RGS4,RPL11,RPL23,RPL5,RPLP1,RPS2,RPS27A,RPS3,RTRAF,SESN2,SOCS7,SPRED1,SPRED2,SPRY2,SPRY4,TCP1,TFAP4,TGFA,TRIB2,TRIB3,TXN,UBA52,UBASH3B,XRCC6,ZFP36 |
| GO_RNA_SPLICING | 0.0e+00 | 0.0e+00 | 1603 | 433 | 57 | AKAP17A,BUD31,C2orf49,CTNNBL1,CWC15,DDX20,DDX39A,DDX47,ECD,GPKOW,LSM5,MAGOH,METTL16,MTREX,NPM1,NUP98,PLRG1,POLR2C,POLR2H,POLR2J,PPIE,PPIL3,PPP2CA,PRMT5,PRPF3,PTBP2,RBM11,RBM19,RBM28,RP9,RPS13,RTCB,RTRAF,SAP18,SF3A1,SF3B6,SMN1,SMN2,SMNDC1,SNRNP27,SNRPB2,SNU13,SNUPN,SRSF1,SRSF3,SRSF7,TARDBP,THOC6,TMBIM6,TXNL4B,U2AF1,U2AF2,USP39,WDR33,WDR77,YBX1,ZRANB2 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1603 | 1869 | 137 | ADORA2B,AGO3,AIMP1,AREG,ATF3,BCL10,BUD31,CANT1,CCL20,CCL5,CD14,CD44,CIB1,CRKL,CSNK1G3,CSNK2A1,CTH,DDIT3,DDX21,DHX36,DNAJC27,DUSP5,DUSP6,DUSP7,EDA2R,EEF1D,EIF2AK2,EPGN,EREG,ERFE,EZH2,FAS,FGF8,FLT1,G3BP2,GADD45A,GDF15,GFI1,GOLT1B,GRB10,HAX1,HBEGF,HES1,HOMER2,HSP90AA1,HSP90AB1,IL23A,INHBE,IRAK2,KARS1,KLHDC10,LARS1,LILRA5,LURAP1L,MAP2K1,MAP3K21,MAP3K4,MAPK9,MAPKAPK3,MAPKAPK5,MCL1,MFHAS1,MMS19,MSX1,MTDH,NADK,NETO1,NEUROD2,NLE1,NMT1,NUP93,PAFAH1B1,PAIP2,PDCD5,PDGFA,PDIA3,PELI2,PELO,PIH1D1,PIM2,PIP4P1,PLK2,PMAIP1,PRKAA1,PRMT1,PRMT5,PRNP,PRR5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RACK1,RAD9A,RAP1B,RELL1,RGS4,RHEB,RPL11,RPL23,RPL26,RPS27A,RPS3,RWDD1,SEC13,SEMA3A,SERP1,SMARCB1,SMURF2,SNAP25,SPHK1,SPRED1,SPRED2,SPRY2,TAF1,TARDBP,TBK1,TFAP4,TFG,TGFA,TLR2,TMEM106A,TUBD1,TXN,UBA52,YWHAE |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1935 | 140 | ABCG2,ANKRD54,ANXA1,ANXA5,ANXA7,BCL10,BPGM,BSCL2,CACNA1F,CCDC47,CCDC66,CCL5,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDK16,CEBPG,CNNM4,CRY1,CUTC,DDIT3,DHX36,DMXL1,EIF5A2,ENY2,ERFE,ERP44,ESRRG,EZH2,FBXL5,FOXA2,FOXC2,GCLC,GCLM,GLRX2,GNL3,GPR3,GRAMD1B,GRB10,H4C2,H4C3,H4C4,HAAO,HAMP,HERPUD1,HK2,HOMER2,HSP90AA1,HSP90AB1,HUS1,IDE,IL4R,IMMT,IREB2,ITPR1,LDB2,MALL,MAP3K4,MAPKAPK5,MCL1,MFHAS1,MICU2,MKS1,MT2A,MYC,MYO5B,NADK,NBN,NDUFAF2,NLE1,NME2,NOP10,NPM1,NR1D1,NR1D2,NR1H2,NUBP1,NUS1,PDE4D,PDIA3,PDIA6,PIH1D1,PMAIP1,PNKP,POC1B,POLD2,POLE4,POT1,PRDM14,PRDX4,PRIM2,PRKAA1,PRKAB2,PRKAR1B,PRMT1,PRNP,QSOX1,RAC1,RACK1,RAP1GDS1,RHEB,RHEX,RP1,RPS14,RPS19,RPS24,RPS6,SEC24A,SELENOK,SELENOS,SESN2,SLC16A1,SLC31A1,SLC39A6,SLC39A7,SLC9B2,SMAD5,SMARCB1,STC2,TCP1,TENT4B,TFRC,TMBIM6,TMEM38B,TMOD3,TNFRSF11B,TPT1,TXN,TXNDC5,UBASH3B,UPF1,WRN,XRCC6,YWHAE,ZC3H8,ZFP36 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1603 | 1030 | 93 | AARS1,AMIGO2,ANXA1,ANXA5,ARF4,ASNS,ATG7,AURKA,BCL10,CCL5,CD44,CFDP1,CIB1,COPS5,CREB3,CSNK2A1,CTH,DFFA,EIF2AK2,EN2,EVI2B,FAS,FGF8,FHL2,FOXC2,FOXQ1,GATA6,GCLC,GCLM,GLO1,GNAI3,HAX1,HERPUD1,HSP90AB1,MCL1,MNAT1,MSX1,MTDH,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,MYC,NAA15,NIBAN2,NLE1,NME2,NPM1,PAK4,PAM16,PDE12,PIH1D1,PIM1,PIM2,PLK2,PLK3,PRKAA1,PRNP,PSMC5,PTRH2,PYCR1,RACK1,RFFL,RPL10,RPS27A,RPS3A,RPS6,RPS6KB1,SELENOS,SGK3,SIAH2,SPHK1,SPRY2,STK40,SYVN1,THOC6,TMBIM6,TMEM161A,TPT1,TRAP1,TXN,TXNDC5,UBA52,UBE2V2,UFM1,URI1,YBX3,YME1L1,YWHAE |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 1567 | 121 | ABCC9,ABCE1,ADAMTS9,AEN,AIM2,AIMP1,ANXA1,APOBEC3A,APOBEC3D,ATG7,BANF1,BATF3,BCL10,CA5B,CCDC47,CCL20,CCL5,CCT5,CD14,CD44,CDC37,CDK4,CEBPG,CFP,CNOT7,COTL1,CXCL2,CXCL3,DDIT3,DDX21,DHX36,DMBT1,DUOX2,EEF1G,EIF2AK2,EPHA2,EPPIN,EPRS1,EREG,FBXO38,FOSL1,G3BP1,G3BP2,GBP3,GBP6,GFI1,H2BC11,H2BC12,H2BC8,HAMP,HMGA1,HSP90AB1,ICAM3,IFNGR2,IL23A,IL4R,IRAK2,LEAP2,LIAS,LILRA5,LSM5,MAPKAPK3,MASP2,MFHAS1,MT2A,MTDH,NOCT,NOP53,NR1D1,NR1H2,ODC1,OTULIN,PDE12,PDE4D,PIM2,PMAIP1,POLR3D,PPM1D,PPP1R14B,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAB27A,RPL13A,RPL30,RPL39,RPS15A,RPS19,RPS27A,RPS6KB1,SEC61A1,SELENOK,SELENOS,SHMT2,SLFN13,SUMO1,TBK1,TLR2,TMEM106A,TPT1,TRAF3,TRIM11,TTC4,UBA52,UBE2D2,UBQLN1,UPF1,URI1,XRCC6,ZFP36 |
| GO_MRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1603 | 503 | 61 | A1CF,AHCYL1,AKAP17A,BUD31,CDK11B,CTNNBL1,CWC15,DDX20,DDX39A,DDX47,DHX36,ECD,GPKOW,LSM5,MAGOH,METTL16,MNAT1,MTREX,NPM1,NUP98,PDE12,PLRG1,POLR2C,POLR2H,POLR2J,PPIE,PPIL3,PRMT5,PRPF3,PTBP2,RBM11,RBM19,RBM28,RNMT,SAP18,SF3A1,SF3B6,SMN1,SMN2,SMNDC1,SNRNP27,SNRPB2,SNU13,SNUPN,SRSF1,SRSF3,SRSF7,TARDBP,TENT2,TENT4B,THOC6,TXNL4B,U2AF1,U2AF2,USP39,WDR33,WDR77,XRN2,YBX1,ZNF473,ZRANB2 |
| GO_NUCLEAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 347 | 50 | AAAS,ABCE1,AHCYL1,ANKRD54,BANF1,DDX19B,DDX20,DDX39A,DNAJC27,EIF6,EMD,ENY2,HMGA1,IPO5,MAGOH,NMD3,NOLC1,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,RGPD5,RIOK2,RPL23,RPS15,SDAD1,SEC13,SMN1,SMN2,SNUPN,SPRN,SRSF1,SRSF3,SRSF7,TARDBP,THOC6,TNPO3,TXN,U2AF1,U2AF2,UPF1,UPF3A,WDR33,XPO1,XPO5,XPOT,YWHAE |
| GO_RIBOSOMAL_LARGE_SUBUNIT_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 29 | 17 | BOP1,NLE1,NOP2,NOP53,RPF2,RPL10,RPL11,RPL12,RPL23A,RPL24,RPL3,RPL38,RPL5,RPL6,RPLP0,RPLP0P6,RSL24D1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 637 | 69 | AURKA,BRSK1,BTG3,CAB39,CBX3,CDC123,CDK4,CNOT1,CNOT7,CRY1,DDIT3,E2F6,E2F7,EVI2B,EZH2,FBXO43,GADD45A,GADD45GIP1,GATA6,HSP90AB1,HUS1,IPO5,KAT2A,MAP2K1,MAX,MEIOC,MYC,NBN,NLE1,NOP53,NPM1,NUBP1,PCGF6,PLK2,PLK3,PRKAA1,PRKAB2,PRMT1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD9A,RHEB,RHNO1,RINT1,RNF2,RPL23,RPL24,RPL26,RPS6,TAF6,TEX14,TFAP4,TIPIN,UXT,ZNF207,ZW10 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 624 | 68 | ABI2,ANAPC5,ANXA1,AP1AR,ARIH2,ARPC5L,AURKA,BAIAP2L2,CARMIL2,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC37,CNOT1,DHX36,EPGN,EREG,FGF8,G3BP1,G3BP2,GNL3,HAX1,HK2,KAT2A,KATNB1,KATNBL1,LMAN1,MAP3K4,MAPK9,MAPKAPK5,MAPRE1,MSX1,NAV3,NBN,NMT1,NPM1,PDCD5,PDCD6IP,PDXP,PFDN2,PFN2,PHF19,PIH1D1,PIWIL2,PLD6,PMAIP1,PNKP,POT1,PPHLN1,PRKAA1,PSRC1,RAB3GAP2,RAC1,RP1,RPS3,RUVBL2,SHCBP1L,SMARCB1,SMPD3,TCP1,TGFA,TMED9,YWHAE,ZMYND10 |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1603 | 1174 | 99 | ABCE1,ADGRG3,AIM2,ANXA1,ANXA5,AURKA,BICD1,BOD1,C9orf72,CAB39,CBARP,CD44,CEBPG,CEP85,CERS1,CIB1,CNRIP1,CNST,CSNK2A1,DDIT3,DFFA,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EIF2S1,EPPIN,EZH2,FOXA2,G3BP2,GADD45A,GFI1,GNAI3,GTPBP4,HDAC4,HERPUD1,IL18BP,IPO5,IRAK2,MDFI,MITD1,MNAT1,MSX1,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,MTRR,NLE1,NPM1,OAZ1,OTULIN,PAM16,PAQR3,PIH1D1,PIM1,PIM2,POT1,PPP1R14B,PPP2CA,PRKAR1B,PRNP,PSMF1,RACK1,RFFL,RGS4,RNF2,RPL11,RPL23,RPL5,RTRAF,RUVBL2,SERPINB5,SERPINI2,SIAH2,SLIT2,SPRED1,SPRED2,SPRY2,SPRY4,SUMO1,TAF1,TEX14,TFAP4,TMBIM6,TRAF3,TRIB2,TRIB3,UBASH3B,UBQLN1,URI1,VCPKMT,YWHAE,ZFP36 |
| GO_REGULATION_OF_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 325 | 47 | AHCYL1,CDK11B,CNOT1,CNOT7,DHX36,EXOSC1,GTPBP1,IGF2BP3,MAGOH,MEIOC,METTL16,NBAS,NOCT,NPM1,NUP98,PABPC4,PDE12,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RBM11,RBM19,RPS27A,SAP18,SRSF1,SRSF3,SRSF7,TARDBP,TENT4B,U2AF2,UBA52,UPF1,XPO1,YBX1,YBX3,ZFP36 |
| GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1603 | 181 | 35 | AURKA,BOP1,BRPF1,CD44,CSNK2A1,HUS1,MAPKAPK5,MSX1,NBN,NOP2,NOP53,NPM1,PHF20,PLK3,PMAIP1,PRKAA1,PRKAB2,PRMT5,RAD9A,RFFL,RHNO1,RMI2,RPF2,RPL11,RPL23,RPL26,RPL5,SPRED1,SPRED2,TAF1,TAF4,TAF4B,TAF6,TBP,WRN |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 856 | 80 | AEN,ASF1A,AURKA,BCCIP,BRSK1,CBX3,CD44,CEBPG,CIB1,CNOT1,CNOT7,COPS5,CRY1,DDIT3,E2F7,EPHA2,GADD45A,H4C2,H4C3,H4C4,HMGA1,HUS1,LIG3,MCL1,MEIOC,MMS19,MNAT1,MORF4L2,MSX1,MUTYH,MYC,NBN,NOP53,NPM1,NUDT1,PLK2,PLK3,PMAIP1,PNKP,POLD2,POLR2C,POLR2H,POLR2J,PPIE,PPM1D,PRIMPOL,PRMT1,PSMD14,PSME4,RAD23A,RAD23B,RAD51B,RAD9A,RHNO1,RINT1,RMI2,RPL26,RPS27A,RPS3,RUVBL2,SESN2,SHLD3,SPRED1,SPRED2,SUMO1,TAF1,TCEA1,TDP1,TFAP4,TIPIN,TMEM161A,TPT1,UBA52,UBE2V2,UPF1,WDR33,WRN,XRCC6,ZNF771,ZRANB3 |
| GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 199 | 36 | CNOT1,CNOT7,DHX36,EXOSC1,GTPBP1,IGF2BP3,MEIOC,METTL16,NBAS,NOCT,NPM1,PABPC4,PDE12,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,TARDBP,TENT4B,UBA52,UPF1,XPO1,YBX1,YBX3,ZFP36 |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1603 | 974 | 86 | ADORA2B,AREG,ATF3,CAB39,CCL20,CCL5,CD44,CIB1,COPS5,CRKL,DNAJC27,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EPGN,EPHA2,EREG,EZH2,FAS,FGF8,FLT1,GADD45A,GDF15,HBEGF,INHBE,IRAK2,KARS1,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPK9,MAPKAPK3,MAPKAPK5,MARK3,MFHAS1,MYC,PAFAH1B1,PAK4,PAQR3,PDGFA,PELI2,PPP2CA,PRKAA1,PRMT1,PRMT5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAP1B,RELL1,RGS4,RPS27A,RPS3,SEMA3A,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,TBC1D10C,TGFA,TMEM106A,TRIB2,TRIB3,UBA52,VRK2,YWHAE,ZFP36 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 802 | 76 | AAAS,ADORA2B,ARIH2,BICD1,BRSK1,BYSL,CCDC66,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDK16,CEP290,CIB1,CNST,CRKL,DHX36,DNAJC27,EIPR1,EMD,ENY2,EPB41,EPHA2,FOXA2,GNL3,GPC6,HAX1,HSP90AA1,HSP90AB1,IL4R,IPO5,LMAN1,MAP2K1,MFHAS1,NADK,NDUFAF2,NMD3,NMT1,NOLC1,NPM1,NR1D1,NUP54,NUP58,NUS1,OAZ1,PDCD5,PDE4D,PID1,PLK3,PMAIP1,PPFIA1,PRKAA1,PRNP,RAC1,RACK1,RINT1,RIOK2,SAPCD2,SESN2,SLC9B2,STAC,TARDBP,TCP1,TMBIM6,TMEM38B,TMEM98,TXN,UBASH3B,XPO1,XPO5,YWHAE,ZFAND1,ZFP36 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 1037 | 89 | AIM2,ANXA1,ANXA5,ARIH2,BICD1,BORA,BYSL,CCDC66,CCL5,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD14,CDK16,CEP290,CIB1,CNST,CRKL,DHX36,DNAJC27,DPH3,EMD,ENY2,EPB41,EPHA2,FOXA2,GNL3,GOLPH3L,GPC6,HAX1,HSP90AA1,HSP90AB1,IL4R,IPO5,ITPR1,KARS1,LILRA5,LMAN1,MFHAS1,NADK,NDUFAF2,NMD3,NMT1,NOLC1,NPM1,NR1D1,NR1H2,NUP54,NUP58,OAZ1,PANX1,PDCD5,PID1,PLK3,PMAIP1,PPFIA1,PPID,PRKAA1,PRNP,RAC1,RACK1,RFX3,RIOK2,RSL1D1,SAPCD2,SEC24A,SELENOK,SERP1,SESN2,SLC16A1,SLC25A6,SLC9B2,SNAP25,STAC,SUMO1,TARDBP,TCP1,TLR2,TMBIM6,TMEM98,TXN,XPO1,XPO5,YWHAE,ZFAND1 |
| GO_MATURATION_OF_SSU_RRNA | 0.0e+00 | 0.0e+00 | 1603 | 47 | 19 | ABT1,BYSL,DCAF13,FAM207A,NGDN,NOB1,NOP14,RIOK1,RIOK2,RPS14,RPS16,RPS19,RPS21,RPS28,RPS8,UTP23,UTP4,UTP6,WDR46 |
| GO_MITOCHONDRIAL_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 1603 | 165 | 32 | AARS1,DAP3,EARS2,ERAL1,GADD45GIP1,GARS1,HARS1,LRPPRC,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,MTO1,NSUN4,POLRMT,PRKAA1,SHMT2,TFB2M,TRIT1,TRNT1,TUFM |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 356 | 47 | AURKA,BRSK1,CBX3,CDK4,CNOT1,CNOT7,E2F6,E2F7,EVI2B,EZH2,FBXO43,GADD45A,HSP90AB1,HUS1,KAT2A,MAX,NBN,NOP53,NPM1,NUBP1,PCGF6,PLK2,PLK3,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RINT1,RNF2,RPL23,RPL26,TEX14,TFAP4,UXT,ZNF207,ZW10 |
| GO_REGULATION_OF_PROTEIN_STABILITY | 0.0e+00 | 0.0e+00 | 1603 | 288 | 42 | A1CF,AURKA,C10orf90,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC37,DERL1,DNLZ,DPM2,GET4,GTPBP4,HSP90AA1,HSP90AB1,HSP90AB3P,KAT2A,MORC3,MSX1,NAA15,NOP53,NPM1,NR1D1,PFN2,PIM1,PIM2,PRNP,RAD23A,RPL11,RPL23,RPL5,SEL1L,SUGT1,SUMO1,SYVN1,TAF1,TARDBP,TCP1,ZNF207 |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1603 | 990 | 85 | ADGRG3,AGO3,AGPAT5,ANKRD54,ANXA1,ARIH2,ARL11,BATF3,BPGM,C12orf29,CEBPG,CIB1,CMTM7,CRKL,CTNNBL1,DHX36,DNAJB9,EIF2AK2,EIF6,EPHA2,EVI2B,GFI1,GLO1,GON4L,H3C14,H4C2,H4C3,H4C4,HAX1,HDAC4,HES1,HOXA3,IL23A,IL4R,IREB2,KAT2A,KAT8,KIRREL3,KLF10,LYL1,MAP2K1,MFAP5,MFHAS1,MYC,NBN,NME2,PABPC4,PAFAH1B1,PDCD2,PGM3,PIM1,PNP,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RHEX,RPS14,RPS19,RPS6,RUNX1,SHLD3,SLC9B2,SMAD5,SMPD3,TENT2,TFRC,TLR2,TMEM98,TMOD3,TYR,UBASH3B,ZC3H8,ZFP36 |
| GO_RNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 0.0e+00 | 1603 | 136 | 29 | AAAS,ABCE1,DDX19B,DDX39A,EIF6,ENY2,MAGOH,NMD3,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,RIOK2,RPS15,SDAD1,SEC13,SRSF1,SRSF3,SRSF7,THOC6,U2AF1,U2AF2,UPF1,WDR33,XPO1,XPO5,XPOT |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | 0.0e+00 | 0.0e+00 | 1603 | 266 | 40 | BYSL,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,INTS13,IPO5,MFHAS1,MORC3,MSX1,NMD3,NOLC1,NOP53,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,PLRG1,RGPD5,RPF2,RPL11,RPL23,SESN2,SNUPN,SPRN,SUMO1,TARDBP,TCP1,TMEM98,TNPO3,TXN,WRN,XPO1,YWHAE |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 872 | 78 | ADORA2B,ANKRD54,BCCIP,BCL10,BORA,CAB39,CCL5,CCNC,CCNJ,CDC37,CDK4,CEP85,CIB1,CRKL,DUSP12,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EEF1A1,EIF2AK2,EPGN,EREG,EZH2,FLT1,FOXA2,GADD45A,GDF15,GTPBP4,HSP90AA1,HSP90AB1,IL23A,IPO5,IRAK2,KARS1,LDB2,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MNAT1,NBN,NPM1,PAK4,PAQR3,PDGFA,PIH1D1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,PSRC1,RACK1,RGS4,RPLP1,RPS27A,RPS3,RTRAF,SESN2,SOCS7,SPRED1,SPRED2,SPRY2,SPRY4,TFAP4,TGFA,TRIB2,TRIB3,TXN,UBA52,UBASH3B,XRCC6 |
| GO_RIBOSOMAL_SMALL_SUBUNIT_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 19 | 13 | ABT1,ERAL1,RPL38,RPS10,RPS14,RPS15,RPS19,RPS27,RPS28,RPS5,RPSA,RRP7A,RRP7BP |
| GO_NUCLEAR_EXPORT | 0.0e+00 | 0.0e+00 | 1603 | 195 | 34 | AAAS,ABCE1,AHCYL1,DDX19B,DDX39A,DNAJC27,EIF6,EMD,ENY2,MAGOH,NMD3,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,RIOK2,RPS15,SDAD1,SEC13,SRSF1,SRSF3,SRSF7,THOC6,TXN,U2AF1,U2AF2,UPF1,WDR33,XPO1,XPO5,XPOT,YWHAE |
| GO_RNA_MODIFICATION | 0.0e+00 | 0.0e+00 | 1603 | 161 | 31 | A1CF,AARS1,APOBEC3A,APOBEC3D,BUD23,CTU1,DIMT1,DPH3,DUS4L,ELP2,EMG1,METTL1,METTL16,METTL2A,MTO1,NOP10,NOP2,NSUN4,NSUN5,PUSL1,QTRT1,QTRT2,RNMT,TFB1M,TFB2M,THG1L,THUMPD3,TRIT1,TRMO,TRMT61A,TYW5 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1603 | 860 | 77 | ATF3,BATF3,CNBP,CNOT1,CNOT7,CREM,CRY1,DDIT3,DDX20,DICER1,DLX2,DRAP1,E2F6,E2F7,ELK4,EMX2,ERF,EZH2,FHL2,FOSB,FOXC2,FOXQ1,GATA6,GFI1,HAMP,HDAC4,HES1,KLF10,KLF16,LDB2,MAX,MBD1,MDFI,MIER2,MSX1,MTDH,MTF1,MYC,MYT1L,NOP53,NR1D1,NR1D2,NR1H2,PCGF6,PLK3,PPID,PRDM14,RNF2,RPL10,RPL23,RPS14,RPS27A,RUNX1,SAP130,SARS1,SIM2,SMAD5,SMURF2,SUMO1,TAF1,TBX20,TFAP2C,TMBIM6,TRIB3,TRIM33,TXN,UBA52,URI1,UXT,VAX1,XPO1,YBX1,YBX3,ZC3H8,ZFP36,ZNF451,ZNF567 |
| GO_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1603 | 1457 | 108 | AAAS,ACRBP,ADAMTS1,ANXA1,ANXA5,AREG,AURKA,CCDC36,CCT2,CCT3,CCT4,CCT5,CCT7,CCT8,CDK16,CIB1,CREM,CRKL,DDX20,DHX36,E2F7,EIF2B2,EIF2S2,EIF4H,EIF5A2,EPPIN,EREG,ETV5,EXD1,FAM9C,FBXO43,FGF8,FOSB,FOSL1,FOXF2,GATA6,GNPDA1,GPR3,HDAC4,HERC4,HES1,HSP90AB1,HUS1,IL4R,INTS13,MAFF,MAP2K1,MAP3K4,MDFI,MEIOC,MSX1,NAMPT,NBN,NUDT1,OR7C1,OSGIN2,PAFAH1B1,PAIP2,PAQR5,PGM3,PHC2,PIWIL1,PIWIL2,PLD6,PPP2CA,PRDM14,PRDX4,PSMD13,PSME4,RAD23B,RAD51B,RFX2,RNF114,RNF2,RPL29,RPS6,RPS6KB1,RTCB,SEMA3A,SERPINB5,SFMBT1,SHCBP1L,SLC9B2,SLIT2,SMAD5,SMURF2,SNU13,SPAG1,SPATA2,SPATA5,SPIN2A,STC2,TAF4,TAF4B,TBP,TCP1,TERB2,TEX14,TFAP2C,TNC,TRIM36,USP42,WBP2NL,WDR33,WDR77,XRN2,YBX3,ZW10 |
| GO_PROTEIN_POLYUBIQUITINATION | 0.0e+00 | 0.0e+00 | 1603 | 312 | 43 | ANAPC5,ARIH1,ARIH2,BLMH,C10orf90,CDC23,CDC26,CDC34,FBXL5,FBXO10,FBXO38,FOXF2,HECTD2,PELI2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RFFL,RNF114,RNF19A,RPS27A,SIAH2,SMURF2,SYVN1,TAF1,TPP2,TRIM36,UBA52,UBE2D2,UBE2G1,UBE2V2,UNKL |
| GO_PROTEIN_STABILIZATION | 0.0e+00 | 0.0e+00 | 1603 | 185 | 33 | A1CF,C10orf90,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC37,DNLZ,GTPBP4,HSP90AA1,HSP90AB1,HSP90AB3P,MORC3,MSX1,NAA15,NOP53,NPM1,PFN2,PIM1,PIM2,RPL11,RPL23,RPL5,SEL1L,SUGT1,SUMO1,SYVN1,TAF1,TCP1,ZNF207 |
| GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 0.0e+00 | 0.0e+00 | 1603 | 288 | 41 | ASNS,ATF3,CANX,CCDC47,CHAC1,COPS5,CREB3,CTH,CXXC1,DDIT3,DERL1,DNAJB9,EIF2AK2,EIF2S1,ERP44,FKBP14,GET4,GFPT1,GOSR2,HERPUD1,ITPR1,PDIA3,PDIA6,PMAIP1,RACK1,SEC61B,SEL1L,SELENOK,SELENOS,SERP1,SESN2,SRPRA,STC2,SYVN1,TARDBP,TBL2,TMBIM6,TRIB3,UBA5,UBQLN1,UFM1 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1603 | 1198 | 94 | ARF4,ATF3,CASK,CCNC,CDK8,CEBPG,CEBPZ,CHCHD2,CNBP,CNOT7,COPS5,CREB3,CREM,DDIT3,DHX36,DLX2,E2F6,E2F7,ECD,ELK4,ELOC,EN2,ESRRG,ETV4,ETV5,FOSB,FOSL1,FOXA2,FOXC2,FOXF2,GABPB1,GABPB2,GATA6,GFI1,GNL3,GTF2B,HAX1,HDAC4,HES1,HMGA1,HOXA3,IER2,IER5,IL23A,KAT2A,KAT8,KLF10,LDB2,MAFF,MAX,MNAT1,MORF4L2,MSX1,MTF1,MYC,MYT1L,NAMPT,NEUROD2,NME2,NPM1,NR1D1,NR1D2,NR1H2,PCGF6,PELP1,PID1,PSMC5,RFX2,RFX3,RPS27A,RTRAF,RUNX1,RUVBL2,SESN2,SETD3,SIM2,SMAD5,SMARCB1,SS18L1,TAF1,TAF4,TAF4B,TBK1,TBX20,TCEA1,TFAP2C,TFAP4,TLR2,UBA52,XRCC6,YBX1,ZNF143,ZNF567,ZNF609 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1603 | 1026 | 85 | ADORA2B,AGO3,AREG,BCL10,CANT1,CCL20,CCL5,CD14,CD44,CIB1,CRKL,CTH,DDIT3,DDX21,DHX36,DNAJC27,DUSP5,DUSP6,DUSP7,EDA2R,EEF1D,EIF2AK2,EPGN,EREG,EZH2,FGF8,FLT1,GADD45A,GDF15,GOLT1B,HAX1,HBEGF,HSP90AA1,HSP90AB1,IL23A,IRAK2,KARS1,KLHDC10,LARS1,LILRA5,LURAP1L,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MCL1,MFHAS1,MSX1,MTDH,NEUROD2,PDGFA,PELI2,PIH1D1,PIM2,PIP4P1,PLK2,PMAIP1,PRKAA1,PRMT1,PRR5,RAC1,RACK1,RAD9A,RAP1B,RELL1,RHEB,RPL11,RPL23,RPL26,RPS27A,RPS3,SEC13,SEMA3A,SPHK1,SPRED1,SPRED2,SPRY2,TBK1,TFG,TGFA,TLR2,TMEM106A,TXN,UBA52 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 777 | 71 | ABCE1,AEN,AIM2,APOBEC3A,APOBEC3D,AURKA,BANF1,BCL10,CCL5,CD14,CDC37,CIB1,CNOT7,DMBT1,EIF2AK2,EREG,GFI1,GTF2B,HDAC4,HSP90AB1,ICAM3,IFNGR2,IL23A,INTS13,IRAK2,MAPKAPK3,MFHAS1,NOP53,NR1D1,NR1H2,OTULIN,PDE12,POLR2C,POLR2H,POLR2J,POLR3D,PPID,PPIE,PRDX4,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD23A,RPS19,RPS27A,SELENOK,SMARCB1,SMURF2,SUMO1,TARDBP,TBK1,TFAP4,TLR2,TRAF3,TRIM11,UBA52,UBE2D2,UBQLN1,XRCC6,ZFP36 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1603 | 1698 | 118 | ABCC9,AHCYL1,ANXA1,ANXA5,AREG,ASNS,ATG7,BCL10,CBX3,CCL5,CD14,CDK16,CDK4,CERS1,CRKL,CRY1,CXCL2,CXCL3,DDX18,DHX36,DUOX2,EIF2B2,EIF4EBP1,EIF6,ENY2,EPRS1,EREG,ERFE,EZH2,FOSB,FOSL1,FOXA2,FOXC2,GCLC,GCLM,GDF15,GFI1,GLRX2,GNAI3,GRAMD1B,GRAMD1C,GRB10,HAMP,HOMER2,HRH1,HSP90AB1,HTR7,IDE,IPO5,IRAK2,KLF10,KLF16,LARS1,LIAS,MAPK9,MAPKAPK3,MARS1,MAX,MTDH,MTR,NADK,NAMPT,NDUFAF2,NET1,NME2,NOCT,NR1D1,NR1H2,OVCA2,PANX1,PDE4D,PDXP,PID1,PIH1D1,PIM1,PLK3,PRKAA1,PRKAR1B,PRMT5,PRNP,PSMD14,PYCR1,RAC1,RACK1,RAP1B,RGS4,RPL10A,RPL15,RPL23,RPS3,RPS6KB1,RUVBL2,RWDD1,SELENOS,SESN2,SHMT2,SLC1A2,SLC9B2,SLIT2,SMARCB1,SMPD3,STC2,TAF1,TFAP4,TLR2,TMBIM6,TMEM161A,TNC,TOMM20,TRAP1,TRIB3,TUFM,TXN,TYR,UBR1,UPF1,ZFAND1,ZFP36 |
| GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1603 | 482 | 53 | ADAMTS1,ANAPC5,ANXA1,AURKA,BRSK1,CDC23,CDC26,CDK4,CEP290,CNOT1,CNOT7,E2F7,ECD,EZH2,GADD45A,HSP90AA1,HUS1,MAPRE1,NBN,NEDD1,NOP53,NPM1,PAFAH1B1,PLK2,PLK3,PLRG1,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD51B,RINT1,RIOK2,RPL26,SSNA1,TAF1,TEX14,TFAP4,TMOD3,YWHAE,ZNF207,ZW10 |
| GO_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 435 | 50 | AAAS,ADORA2B,ANXA1,CD320,CRY1,DUSP12,ECD,EIF6,ERFE,FOXA2,GFI1,HDAC4,HRH1,KAT2A,MTCO2P12,NFYA,NLN,NR1D1,NR1H2,NUP54,NUP58,NUP88,NUP93,NUP98,OAZ1,ODC1,PGAM1,PID1,PMAIP1,PRKAA1,PRKAB2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,SEC13,SELENOS,SESN2,SMPD3,TRIB3 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 1429 | 104 | ADORA2B,AGAP7P,AGAP9,AHSA1,AIM2,ANKRD27,ARF4,ARFGAP3,ARHGAP18,ARHGAP33,ARHGEF1,ARL1,BCL10,BLID,BORA,CAB39,CCL20,CCL5,CCT2,CCT4,CHTF8,CIB1,CLPX,CRKL,DOCK5,DUSP12,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EPHA2,EREG,EZH2,FAS,FLT1,GADD45A,GCLM,GDF15,GNAI3,HSP90AA1,HSP90AB1,IL23A,IRAK2,KARS1,LARS1,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MNAT1,MYC,NBN,NET1,NPM1,NR1H2,NUS1,PAK4,PDCD2,PDCD5,PDGFA,PFN2,PIH1D1,PITRM1,PMAIP1,PNKP,POT1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,PSMD14,PSME4,PSRC1,RAB3GAP2,RACK1,RAP1GDS1,RAPGEF6,RGPD5,RGS17,RGS4,RGS5,RPLP1,RPS2,RPS27A,RPS3,SEC23A,SPRY2,TBC1D10C,TBC1D14,TCEA1,TCP1,TFAP4,TGFA,TRIB3,TXN,UBA52,WRN,XRCC6 |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 0.0e+00 | 0.0e+00 | 1603 | 1200 | 92 | ABCC9,ABCE1,AEN,AIM2,AIMP1,ANXA1,APOBEC3A,APOBEC3D,ATG7,BCL10,CCL20,CCL5,CD14,CD44,CDC37,CEBPG,CFP,CNOT7,COTL1,DDX21,DHX36,DMBT1,EIF2AK2,EPHA2,EPPIN,EPRS1,EREG,G3BP1,G3BP2,GBP3,GBP6,GFI1,H2BC11,H2BC12,H2BC8,HAMP,HSP90AB1,ICAM3,IFNGR2,IL23A,IL4R,IRAK2,LEAP2,LILRA5,MAPKAPK3,MASP2,MFHAS1,MT2A,NOP53,NR1D1,NR1H2,OTULIN,PDE12,PMAIP1,POLR3D,PPP1R14B,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAB27A,RPL13A,RPL30,RPL39,RPS19,RPS27A,RPS6KB1,SEC61A1,SELENOK,SHMT2,SLFN13,SUMO1,TBK1,TLR2,TMEM106A,TRAF3,TRIM11,TTC4,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | 0.0e+00 | 0.0e+00 | 1603 | 297 | 40 | ABT1,AEN,AGO3,BOP1,CCDC36,CNOT1,CNOT7,DFFA,DICER1,EDC3,EXD1,EXOSC1,G3BP1,MRPL44,NOB1,NOCT,NOP14,PAM16,PDE12,PELO,PIWIL1,PIWIL2,PLD6,PNKP,POLD2,RAD9A,RPP30,RPP40,RPS21,RPS27A,SLFN13,TATDN1,TDP1,TSN,UBA52,UTP23,WRN,XRN2,ZFP36,ZRANB3 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1247 | 94 | ADORA2B,ALG10B,AREG,ATG7,BCAR3,BCL10,BORA,CAB39,CCL20,CCL5,CD44,CIB1,CRKL,CRY1,DERL1,DNAJC27,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EPGN,EREG,EZH2,FAS,FGF8,FLT1,GADD45A,GDF15,GNL3,HAX1,HBEGF,HDAC4,HES1,HSP90AA1,HSP90AB1,IL23A,INHBE,IRAK2,KARS1,KAT2A,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPK9,MAPKAPK3,MAPKAPK5,MARK2,MFHAS1,MNAT1,MOB2,NBN,NOP53,NPM1,PAK4,PDGFA,PELI2,PFN2,PHF19,PIH1D1,PIWIL2,PPP2CA,PRKAA1,PRKAR1B,PRMT1,PRNP,PRR5,PRRC1,PSRC1,RAB3GAP2,RAC1,RACK1,RAP1B,RELL1,RPLP1,RPS2,RPS27A,RPS3,RUVBL2,SEMA3A,SMARCB1,SPHK1,SPRY2,TBK1,TGFA,TMEM106A,TRIB3,TXN,UBA52,UBQLN1,WDFY2,XRCC6 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1189 | 91 | AGO3,ATF3,BOD1,C8orf88,C9orf72,CD44,CEP85,CHAC1,CIB1,CNOT1,CNOT7,CRKL,CRY1,CSNK2A1,DHX36,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EIF2AK2,EIF2S1,EIF4EBP1,EIF6,EPPIN,EPRS1,GADD45A,GCLC,GTPBP4,HBEGF,HERPUD1,HSP90AB1,IDE,IGF2BP3,IPO5,IREB2,METTL16,MFHAS1,MYC,N4BP1,NLE1,NOP53,NPM1,NR1H2,PAFAH1B1,PAIP2,PAQR3,PDE4D,PID1,PIH1D1,PNKP,PPP1R14B,PPP2CA,PRKAA1,PRKAR1B,PRNP,PSMF1,RACK1,RFFL,RGS4,RPL11,RPL13A,RPL23,RPL5,RPS3,RTRAF,SERPINB5,SERPINI2,SESN2,SIAH2,SLIT2,SMARCB1,SPRED1,SPRED2,SPRY2,SPRY4,SVBP,TAF1,TARDBP,TBC1D10C,TFAP4,TMEM98,TRIB2,TRIB3,U2AF2,UBASH3B,UPF1,URI1,YWHAE,ZFP36,ZNF451 |
| GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS | 0.0e+00 | 0.0e+00 | 1603 | 345 | 43 | BUD31,CTNNBL1,CWC15,DDX20,DDX39A,GPKOW,LSM5,MAGOH,METTL16,MTREX,NPM1,NUP98,PLRG1,POLR2C,POLR2H,POLR2J,PPIE,PPIL3,PRMT5,PRPF3,PTBP2,RBM11,RBM19,SAP18,SF3A1,SF3B6,SMN1,SMN2,SMNDC1,SNRNP27,SNRPB2,SNU13,SNUPN,SRSF1,SRSF3,SRSF7,TXNL4B,U2AF1,U2AF2,USP39,WDR33,WDR77,YBX1 |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 406 | 47 | ABCE1,ADORA2B,AP1AR,AP3M2,AP3S2,AREG,ARFGAP3,BCCIP,BICD1,BOD1,C17orf75,CDC23,EIF6,GOSR2,IL4R,KATNB1,LMAN1,LRPPRC,MCFD2,MEIOC,MREG,NMD3,NPM1,NUP88,PAFAH1B1,PSRC1,RAB27A,RAB27B,RIOK2,RPS15,SAPCD2,SDAD1,SEC13,SEC23A,SEC24A,SEC24D,SPRY2,STARD3NL,SYNE3,TERB2,TFG,TGFA,TMED9,TRAPPC6B,UXT,XPO1,ZW10 |
| GO_TRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1603 | 128 | 26 | AARS1,C2orf49,CTU1,DPH3,DUS4L,ELP2,KARS1,METTL1,METTL2A,MTO1,PUSL1,QTRT1,QTRT2,RPP30,RPP40,RTCB,RTRAF,SARS1,THG1L,THUMPD3,TRIT1,TRMO,TRMT61A,TRNT1,TYW1B,TYW5 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION | 0.0e+00 | 0.0e+00 | 1603 | 250 | 36 | CCNC,CDK4,CDK8,DHX36,ESRRG,FOSL1,GTF2B,GTF2E2,H4C2,H4C3,H4C4,MED26,MED8,MNAT1,NR1D1,NR1D2,NR1H2,PIH1D1,POLR1E,POLR2C,POLR2H,POLR2J,POLRMT,PPM1D,PSMC5,SGF29,SMARCB1,TAF1,TAF1A,TAF1D,TAF4,TAF4B,TAF6,TBP,TFB2M,ZNF451 |
| GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA | 0.0e+00 | 0.0e+00 | 1603 | 35 | 15 | ABT1,BYSL,DCAF13,FAM207A,NGDN,NOP14,RPS14,RPS16,RPS19,RPS21,RPS8,UTP23,UTP4,UTP6,WDR46 |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 1603 | 1680 | 114 | ABCB11,ABCC4,ADGRG3,ADORA2B,AIM2,AIMP1,ANXA1,ANXA5,APBA1,ARFGAP3,ATAD3B,ATG7,ATP11B,BRSK1,CAB39,CANT1,CANX,CASK,CBARP,CCL5,CCT2,CCT8,CD14,CD44,CDK16,CEP290,CFP,CKLF,COPB1,COPS5,COTL1,CRACR2A,CRY1,DDOST,DHX36,DOC2A,DPH3,EEF1A1,ENY2,ERP44,EXOC3L2,FOXA2,GOLPH3L,GTPBP2,HK2,HSP90AA1,HSP90AB1,IL4R,ILF2,ITPR1,KARS1,LILRA5,M6PR,MON1A,MTCO2P12,NADK,NAPB,NDUFAF2,NIBAN2,NME2,NR1D1,NR1H2,OLA1,PAFAH1B1,PANX1,PDCD6IP,PDGFA,PFN2,PGAM1,PNP,PPFIA1,PPID,PPIE,PRDX4,PROCA1,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAB27B,RAB2B,RABEPK,RAC1,RAP1B,RFX3,SEC24A,SEL1L,SELENOK,SERP1,SLC16A1,SLC1A2,SLC1A5,SLC25A6,SLC9B2,SMPD3,SNAP25,STX19,SVBP,TARDBP,TBC1D10C,TLR2,TMBIM6,TMEM106A,TMEM167A,TMEM38B,TVP23B,TXNDC5,XRCC6 |
| GO_TELOMERE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 175 | 30 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,GNL3,H4C2,H4C3,H4C4,HSP90AA1,HSP90AB1,HUS1,MAP3K4,MAPKAPK5,MYC,NBN,NOP10,PNKP,POLD2,POLE4,POT1,PRIM2,TCP1,TENT4B,UPF1,WRN,XRCC6 |
| GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | 0.0e+00 | 0.0e+00 | 1603 | 313 | 40 | AIM2,CCL20,CCL5,CD14,CIB1,EDA2R,GBP3,H2BC11,HAMP,HDAC4,KARS1,KAT2A,NR1D1,OTULIN,PID1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RFFL,RPS3,RPS6KB1,SMPD3,SPATA2,SPHK1,TNFRSF11B,TRAF3,YBX3,ZFP36 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 1454 | 102 | AHCYL1,ANXA1,ANXA5,ASNS,ATG7,CBX3,CCL5,CD44,CDK4,CIB1,CNOT1,CRKL,CRY1,DDX18,DYNC1LI2,EEF1A1,EIF4EBP1,EPRS1,ERFE,ESRRG,EZH2,FAM83G,FGF8,FHL2,FOSB,FOXC2,GATA6,GCLC,GCLM,GDF15,GNAI3,GRB10,HDAC4,HES1,HRH1,HSP90AB1,HTR7,IDE,IPO5,KAT2A,KCTD6,KLF10,KLF16,LARS1,MARS1,MAX,MSX1,NAMPT,NBL1,NR1D1,NR1D2,NR1H2,PDCD5,PDE4D,PDXP,PELO,PID1,POLR2C,POLR2H,POLR2J,PRDM14,PRKAA1,PRKAR1B,PRMT5,PRNP,RAP1B,RGMB,RGS4,RPL23,RPL8,RPS27A,RPS6KB1,RUNX1,RUVBL2,RWDD1,SELENOS,SESN2,SHMT2,SLIT2,SMAD5,SMPD3,SMURF2,SPRED1,SPRED2,SPRY2,SPRY4,TAF1,TFAP4,TMEM38B,TNC,TRIB3,TRIM33,UBA5,UBA52,UBR1,UFM1,UFSP2,URI1,USP15,ZCCHC18,ZFP36,ZNF451 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 537 | 54 | ARIH2,BICD1,BYSL,CCDC66,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CEP290,CIB1,CNST,CRKL,DNAJC27,EMD,EPB41,EPHA2,GNL3,GPC6,HAX1,HSP90AA1,HSP90AB1,IPO5,LMAN1,MFHAS1,NMD3,NMT1,NOLC1,NPM1,NUP54,NUP58,OAZ1,PDCD5,PID1,PLK3,PMAIP1,PPFIA1,PRKAA1,PRNP,RACK1,RIOK2,SAPCD2,SESN2,STAC,TARDBP,TCP1,TMEM98,TXN,XPO1,XPO5,YWHAE,ZFAND1 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 767 | 67 | AIM2,ANXA1,ANXA5,ARIH2,CCL5,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD14,CDK16,CEP290,CIB1,CNST,DHX36,DNAJC27,DPH3,EMD,ENY2,FOXA2,GOLPH3L,HAX1,IL4R,IPO5,ITPR1,KARS1,LILRA5,LMAN1,NADK,NDUFAF2,NMT1,NOLC1,NR1D1,NR1H2,NUP54,NUP58,OAZ1,PANX1,PDCD5,PLK3,PMAIP1,PPID,PRKAA1,PRNP,RAC1,RACK1,RFX3,RIOK2,SEC24A,SELENOK,SERP1,SLC16A1,SLC25A6,SLC9B2,SNAP25,TARDBP,TCP1,TLR2,TMBIM6,TXN,XPO1,XPO5,YWHAE,ZFAND1 |
| GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 540 | 54 | AIM2,AURKA,BCL10,CCL5,CD14,CIB1,CNOT7,DMBT1,EREG,GFI1,GTF2B,HDAC4,ICAM3,IRAK2,MAPKAPK3,MFHAS1,NOP53,NR1D1,OTULIN,PDE12,POLR2C,POLR2H,POLR2J,POLR3D,PPID,PPIE,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD23A,RPS19,RPS27A,SMARCB1,SMURF2,TBK1,TFAP4,TLR2,TRAF3,TRIM11,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1603 | 751 | 66 | AAAS,ATG7,CD44,CEBPG,CHCHD2,COPS5,CREB3,CRY1,DDIT3,DNAJB9,EDA2R,EIF2AK2,FAS,GADD45A,HERPUD1,HMGA1,HSP90AA1,HSP90AB1,IER5,KARS1,KLHDC10,MAP2K1,MAP3K21,MAP3K4,MCL1,MFHAS1,MMS19,MSX1,MYC,NAMPT,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,PAFAH1B1,PLK2,PMAIP1,PRMT1,PYCR1,RACK1,RAD9A,RELL1,RINT1,RMI2,RPL26,RPS3,RSL1D1,SEC13,SELENOS,SEMA3A,SHLD3,SPHK1,SPRED1,SPRED2,SYVN1,TMBIM6,TMEM161A,TPT1,TRAP1,TXN,UBE2V2,UBQLN1,YBX3,YWHAE |
| GO_MITOCHONDRIAL_TRANSLATION | 0.0e+00 | 0.0e+00 | 1603 | 137 | 26 | AARS1,DAP3,EARS2,ERAL1,GADD45GIP1,GARS1,HARS1,LRPPRC,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,NSUN4,SHMT2,TUFM |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1603 | 791 | 68 | ABCE1,AIM2,ANXA1,BOLA2B,CANX,CCL20,CCL5,CD44,CDC37,CIB1,CNOT7,CRKL,CXCL2,CXCL3,DUOX2,EDA2R,EREG,GFI1,H2BC11,H3C14,HSP90AA1,HSP90AB1,IFNGR2,IL15RA,IL18BP,IL23A,IL4R,IRAK2,KARS1,MCL1,MT2A,MYC,NR1H2,OTULIN,PAFAH1B1,PELI2,PIM1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RAP1B,RFFL,RHEX,RPLP0,RPS27A,RUNX1,SLIT2,SPATA2,SPHK1,SUMO1,TBK1,TCP1,TNFRSF11B,TRAF3,UBA52,VRK2 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 1721 | 114 | AHCYL1,ANXA1,ANXA5,AREG,ASNS,ATG7,CBX3,CCL5,CD44,CDK4,CIB1,CNOT1,CRKL,CRY1,DDX18,DYNC1LI2,EEF1A1,EIF2B2,EIF4EBP1,EIF6,EPRS1,EREG,ERFE,ESRRG,EZH2,FAM83G,FGF8,FHL2,FOSB,FOSL1,FOXC2,GATA6,GCLC,GCLM,GDF15,GNAI3,GRB10,HDAC4,HES1,HRH1,HSP90AB1,HTR7,IDE,IER2,IPO5,KAT2A,KCTD6,KLF10,KLF16,LARS1,LONP1,MARS1,MAX,MMS19,MSX1,NAMPT,NBL1,NME2,NR1D1,NR1D2,NR1H2,PDCD5,PDE4D,PDXP,PELO,PID1,POLR2C,POLR2H,POLR2J,PRDM14,PRKAA1,PRKAR1B,PRMT5,PRNP,RAP1B,RGMB,RGS4,RPL23,RPL8,RPS27A,RPS6KB1,RUNX1,RUVBL2,RWDD1,SELENOS,SESN2,SHMT2,SLIT2,SMAD5,SMPD3,SMURF2,SPRED1,SPRED2,SPRY2,SPRY4,STC2,TAF1,TFAP4,TLR2,TMEM38B,TNC,TOMM20,TRIB3,TRIM33,UBA5,UBA52,UBR1,UFM1,UFSP2,URI1,USP15,ZCCHC18,ZFP36,ZNF451 |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 528 | 53 | APOO,ARIH2,ATAD3B,ATAD3C,ATG7,CDC37,CHCHD2,COX10,DNLZ,GABPB1,GCLC,GCLM,HAX1,HK2,HSP90AA1,HSPA4,IMMT,KAT2A,LIG3,LMAN1,LONP1,MARK2,MSTO1,MTFP1,MTFR1,NDUFA5,NDUFAF2,NDUFAF4,NDUFAF7,NDUFB11,NMT1,PAM16,PDCD5,PID1,PIM2,PITRM1,PLD6,PMAIP1,POLRMT,PRKAA1,SESN2,SLC25A6,TFB1M,TFB2M,TIMM13,TIMM23B,TIMM9,TMEM126B,TMEM70,TOMM20,TOMM34,YME1L1,YWHAE |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 1603 | 1061 | 82 | ABCC4,ABCC9,ABCG2,AIM2,ANXA1,AREG,ASNS,ATG7,BCAR3,BLMH,CBX3,CD14,CD320,CDK4,CERS1,CRKL,CYP2C19,DUSP6,EIF4EBP1,EMX2,EZH2,FGF8,FOSB,FOSL1,GATA6,GCLC,GCLM,GLRX2,GNAI3,HAMP,HDAC4,HOMER2,HRH1,HSP90AB1,HTR7,KCNK1,KLF16,MSX1,MT2A,MTR,MYC,NET1,PANX1,PDXP,PNP,PPP2R2A,PRKAA1,PRMT5,PRNP,PSMD14,PYCR1,RACK1,RAP1B,RGS17,RGS4,RPL10A,RPL15,RPL18A,RPS3,RPS6KB1,SLC1A2,SLC1A5,SLC25A6,SLC31A1,SLC36A4,SLC7A1,SLC7A5,SLIT2,SMPD3,SRP68,TAF1,TFAP4,TFRC,TLR2,TMBIM6,TMEM38B,TNC,TNFRSF11B,TRAP1,TUFM,TXN,XPO1 |
| GO_MRNA_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 151 | 27 | AAAS,DDX19B,DDX39A,EIF5A2,ENY2,G3BP2,IGF2BP3,LRPPRC,MAGOH,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,SEC13,SRSF1,SRSF3,SRSF7,THOC6,U2AF1,U2AF2,UPF1,UPF3A,WDR33,XPO1,ZFP36 |
| GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 339 | 41 | AURKA,BRSK1,BTG3,CDK4,CNOT1,CNOT7,E2F7,EZH2,GADD45A,GADD45GIP1,HUS1,MEIOC,NBN,NLE1,NOP53,PLK2,PLK3,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD9A,RINT1,RPL24,RPL26,RPS6,TEX14,TIPIN,ZNF207,ZW10 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1603 | 1208 | 89 | AHCYL1,ANXA1,ANXA5,BCL10,CBX3,CCL5,CD14,CDK16,CDK4,CERS1,CRKL,CXCL2,CXCL3,DDX18,DHX36,EIF4EBP1,ENY2,EPRS1,ERFE,EZH2,FOXA2,FOXC2,GCLC,GCLM,GDF15,GFI1,GLRX2,GNAI3,GRAMD1B,GRAMD1C,GRB10,HAMP,HRH1,HTR7,IDE,IPO5,IRAK2,KLF10,KLF16,LARS1,MAPK9,MARS1,MAX,MTDH,MTR,NADK,NAMPT,NDUFAF2,NET1,NME2,NR1D1,NR1H2,PDE4D,PDXP,PID1,PIH1D1,PIM1,PRKAA1,PRKAR1B,PRMT5,PRNP,PYCR1,RAC1,RACK1,RAP1B,RGS4,RPL23,RPS3,RPS6KB1,RUVBL2,RWDD1,SELENOS,SESN2,SHMT2,SLC9B2,SLIT2,SMARCB1,SMPD3,TAF1,TFAP4,TLR2,TNC,TRAP1,TRIB3,TXN,UBR1,UPF1,ZFAND1,ZFP36 |
| GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 0.0e+00 | 0.0e+00 | 1603 | 201 | 31 | ASNS,ATF3,CANX,CHAC1,COPS5,CREB3,CTH,CXXC1,DDIT3,DERL1,DNAJB9,EIF2AK2,EIF2S1,ERP44,FKBP14,GFPT1,GOSR2,HERPUD1,HSP90AA1,HSP90AB1,HSPA13,HSPA4,PDIA6,RACK1,SELENOS,SERP1,SRPRA,STC2,SYVN1,TBL2,TMBIM6 |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 1604 | 108 | ABCA10,ABCB11,ABCC4,ABCC9,ABCG2,AHCYL1,ALG10B,ANXA5,ATP11B,CAB39,CACNA1F,CBARP,CNNM4,COX10,COX4I1,CRACR2A,DDIT3,DERL1,DNLZ,EIF2S1,EIF2S2,EIF2S3,ERFE,GABRA2,GRB10,HAMP,HK2,ITPR1,KCNG1,KCNG4,KCNK1,KCNQ5,MCL1,MFSD2A,MFSD2B,MICU2,MTCO2P12,NETO1,NIPAL4,OAZ1,PAM16,PANX1,PDE4D,PID1,PIM1,PKD2L2,PRKAB2,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RGS4,RHBG,RHD,RPS27A,RPS6KB1,SEC61A1,SEC61B,SEL1L,SELENOS,SESN2,SGK3,SLC10A5,SLC16A1,SLC16A6,SLC1A2,SLC1A5,SLC25A14,SLC25A6,SLC31A1,SLC35A2,SLC35A3,SLC35D2,SLC36A4,SLC39A6,SLC39A7,SLC6A15,SLC7A1,SLC7A5,SLC7A9,SLC9B2,SLCO4A1,SLCO5A1,SNAP25,STAC,SUMO1,TIMM23B,TMC2,TMEM38B,TOMM20,TRIB3,UBA52,UBASH3B,UBQLN1,YME1L1,YWHAE,ZFAND2B |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 655 | 60 | ADORA2B,BCL10,BORA,CAB39,CCL5,CCT2,CCT4,CHTF8,CIB1,CRKL,DUSP12,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EREG,EZH2,FLT1,GADD45A,GDF15,HSP90AA1,HSP90AB1,IL23A,IRAK2,KARS1,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MNAT1,MYC,NBN,NPM1,PAK4,PDGFA,PIH1D1,PNKP,POT1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,PSRC1,RPLP1,RPS2,RPS27A,RPS3,SPRY2,TCP1,TGFA,TRIB3,TXN,UBA52,XRCC6 |
| GO_REGULATION_OF_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 153 | 27 | ARIH1,ARIH2,AURKA,CSNK1A1,CSNK2A1,FOXF2,GCLC,HERPUD1,HSP90AB1,MAPK9,N4BP1,NOP53,PLK2,PLK3,RACK1,RAD23A,RAD23B,RNF19A,RPL11,RPL23,RPL5,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_RESPONSE_TO_VIRUS | 0.0e+00 | 0.0e+00 | 1603 | 328 | 40 | ABCC9,ABCE1,AEN,AIM2,AIMP1,APOBEC3A,APOBEC3D,ATG7,BANF1,BATF3,CCL5,CCT5,CNOT7,DDX21,DHX36,DMBT1,DUOX2,EEF1G,EIF2AK2,FOSL1,G3BP1,GBP3,HMGA1,IFNGR2,IL23A,NOP53,ODC1,PDE12,PIM2,PMAIP1,POLR3D,RPS15A,SELENOK,SLFN13,TBK1,TPT1,TRAF3,TRIM11,TTC4,URI1 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL | 0.0e+00 | 0.0e+00 | 1603 | 299 | 38 | COPS5,ENY2,KAT2A,MYC,NOP53,OTUD7A,OTULIN,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD23A,RAD23B,RPS27A,SHMT2,SIAH2,SMURF2,SPATA2,STAMBPL1,TOMM20,TRAF3,UBA52,UCHL3,USP12,USP15,USP24,USP39,USP42 |
| GO_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1603 | 271 | 36 | AURKA,BORA,BRSK1,CDK4,CEP290,HSP90AA1,HUS1,MAPRE1,MNAT1,NBN,NEDD1,NOP53,NPM1,PAFAH1B1,PHLDA1,PLK3,PPM1D,PPP2R2A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD51B,RINT1,SSNA1,YWHAE |
| GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 81 | 20 | ANAPC5,AURKA,CDC23,CDC26,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,UBA52 |
| GO_RESPONSE_TO_RADIATION | 0.0e+00 | 0.0e+00 | 1603 | 441 | 47 | AEN,ANXA1,ASNS,BRSK1,CACNA1F,CCDC66,CERS1,CRY1,DHX36,EEF1D,EIF2S1,FNTB,GADD45A,HAMP,HRH1,HUS1,IKBIP,KARS1,MAP3K4,MYC,N4BP1,NAMPT,NET1,NETO1,NMT1,NPM1,PLK3,PNKP,PPID,PPM1D,PRIMPOL,PRKAA1,RAD9A,RHNO1,RP1,RPL26,RUVBL2,SLC1A2,TAF1,TENT2,TIPIN,TMEM161A,TXN,TYR,WRN,XRCC6,ZRANB3 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1603 | 1881 | 120 | ABI2,ADAMTS9,AGO3,ANKRD27,ANKRD54,ANXA1,AP1AR,APOLD1,AREG,ARHGAP33,AURKA,BRSK1,CDH4,CIB1,CPNE5,CRKL,CTH,DDIT3,DHX36,DICER1,DLX2,DOCK5,EIF2AK2,EIF6,EREG,ETV5,EVI2B,EZH2,FBXO38,FGF8,FOXA2,FSTL4,GAK,GATA6,GDF15,GFI1,GOLGA4,H3C14,H4C2,H4C3,H4C4,HAMP,HAX1,HDAC4,HES1,HSP90AB1,IL23A,IL4R,KAT2A,KATNB1,KLF10,MAFF,MAP2K1,MAPK9,MARK2,MOB2,MORF4L2,MSX1,MYC,NBL1,NEUROD2,NIBAN2,NLN,NME2,NOCT,NR1D1,NR1D2,NR1H2,PAFAH1B1,PAQR3,PDCD2,PLEKHB2,PLK2,PNP,PPP2CA,PRMT1,PRMT5,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RFX3,RGS4,RHEB,RHEX,RPS19,RUNX1,SEMA3A,SETD3,SLC9B2,SLIT2,SMAD5,SNAP25,SPRY2,SS18L1,SUCO,TLR2,TMEM98,TRIB2,TRIB3,TRIM11,UBASH3B,UBE2V2,VAX1,WDFY2,YBX1,ZC3H8,ZFP36,ZNF609 |
| GO_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 0.0e+00 | 0.0e+00 | 1603 | 122 | 24 | ASNS,ATF3,CANX,COPS5,CREB3,CTH,CXXC1,DDIT3,DERL1,DNAJB9,EIF2AK2,EIF2S1,FKBP14,GFPT1,GOSR2,HERPUD1,PDIA6,RACK1,SELENOS,SERP1,SRPRA,STC2,SYVN1,TBL2 |
| GO_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1603 | 1005 | 78 | ABCE1,AIM2,ANXA1,APOBEC3A,APOBEC3D,BCL10,CCL20,CCL5,CD14,CD44,CDC37,CEBPG,CFP,CNOT7,DDX21,DHX36,DMBT1,EIF2AK2,EPRS1,EREG,G3BP1,G3BP2,GBP3,GBP6,GFI1,H2BC11,H2BC12,H2BC8,HSP90AB1,ICAM3,IFNGR2,IL23A,IRAK2,LILRA5,MAPKAPK3,MASP2,MFHAS1,MT2A,NOP53,NR1D1,NR1H2,OTULIN,PDE12,POLR3D,PPP1R14B,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAB27A,RPL13A,RPL39,RPS19,RPS27A,RPS6KB1,SEC61A1,SHMT2,SUMO1,TBK1,TLR2,TMEM106A,TRAF3,TRIM11,TTC4,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_METHYLATION | 0.0e+00 | 0.0e+00 | 1603 | 366 | 42 | BHMT2,BUD23,COPRS,CXXC1,DIMT1,EEF1AKMT4,EMG1,ETF1,EZH2,GFI1,METTL1,METTL16,METTL18,METTL2A,MTO1,MTR,MTRR,MYC,NDUFAF7,NIBAN2,NOP2,NSUN4,NSUN5,PCMT1,PHF19,PIH1D1,PIWIL2,PLD6,PPM1D,PRDM14,PRMT1,PRMT5,RNMT,SETD3,SMARCB1,SPOUT1,TFB1M,TFB2M,THUMPD3,TRMO,TRMT61A,VCPKMT |
| GO_AMINO_ACID_ACTIVATION | 0.0e+00 | 0.0e+00 | 1603 | 49 | 16 | AARS1,AIMP1,CARS1,DARS1,EARS2,EPRS1,FARSB,GARS1,HARS1,IARS1,KARS1,LARS1,MARS1,SARS1,TARS1,YARS1 |
| GO_MACROMOLECULE_METHYLATION | 0.0e+00 | 0.0e+00 | 1603 | 306 | 38 | BUD23,COPRS,CXXC1,DIMT1,EEF1AKMT4,EMG1,ETF1,EZH2,GFI1,METTL1,METTL16,METTL2A,MTO1,MTRR,MYC,NDUFAF7,NIBAN2,NOP2,NSUN4,NSUN5,PCMT1,PHF19,PIH1D1,PIWIL2,PLD6,PPM1D,PRDM14,PRMT1,PRMT5,RNMT,SETD3,SMARCB1,TFB1M,TFB2M,THUMPD3,TRMO,TRMT61A,VCPKMT |
| GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 125 | 24 | ARIH1,ARIH2,AURKA,CSNK1A1,FOXF2,GCLC,HERPUD1,HSP90AB1,MAPK9,N4BP1,NOP53,PLK2,PLK3,RACK1,RAD23A,RAD23B,RNF19A,RPL11,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1603 | 1135 | 84 | ABCC4,ABCC9,AHCYL1,ANXA1,ANXA5,AREG,ASNS,ATG7,CCDC47,CDK4,CRKL,CRY1,DDX21,DERL1,DHX36,DNAJB9,DUOX2,EIF2B2,EIF4EBP1,EIF6,EPRS1,EREG,ERFE,EZH2,FOSB,FOSL1,FOXC2,GCLC,GCLM,GDF15,GET4,GNAI3,GRB10,HERPUD1,HOMER2,HRH1,HSP90AB1,HTR7,IDE,IPO5,KLF10,KLF16,LARS1,MARS1,MAX,MTR,NAMPT,NME2,NPM1,PANX1,PDE12,PDE4D,PDXP,PID1,PMAIP1,PPP2R2A,PRKAA1,PRKAR1B,PRMT5,PRNP,RAP1B,RGS17,RGS4,RPL23,RPS6KB1,SEC61B,SEL1L,SELENOS,SESN2,SHMT2,SLC1A2,SLIT2,SMPD3,STC2,SYVN1,TAF1,TLR2,TMBIM6,TMEM38B,TOMM20,TRIB3,TYR,UBQLN1,UBR1 |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 518 | 51 | ADORA2B,BCCIP,CAB39,CCNC,CCNJ,CDC37,CDK4,CIB1,CRKL,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EZH2,FLT1,GADD45A,GDF15,GTPBP4,HSP90AB1,IPO5,IRAK2,KARS1,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MNAT1,PAQR3,PDGFA,PIH1D1,PPP2CA,PRKAA1,PRKAR1B,PSRC1,RGS4,RPS27A,RPS3,SESN2,SPRED1,SPRED2,SPRY2,SPRY4,TFAP4,TGFA,TRIB2,TRIB3,UBA52 |
| GO_TRANSLATIONAL_TERMINATION | 0.0e+00 | 0.0e+00 | 1603 | 105 | 22 | ABCE1,DAP3,EIF5A2,ERAL1,ETF1,GADD45GIP1,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,UPF1 |
| GO_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 326 | 39 | ABCE1,CARMIL2,CCSAP,CIB1,CSNK1A1,DAP3,EIF5A2,ERAL1,ETF1,GADD45GIP1,GAK,HMGA1,KATNB1,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,MYC,NAPB,NAV3,PDXP,RPL23,SMARCB1,TMOD3,UBQLN1,UPF1,VTA1,ZFAND1 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1603 | 942 | 74 | ABI2,AIM2,AMIGO2,ANKRD27,AP1AR,ARHGAP18,ARPC5L,BAIAP2L2,BIN3,BUD23,C10orf90,C9orf72,CARMIL2,CCSAP,CDC34,CEP97,CLDN19,CNOT1,COTL1,DIMT1,DYNC2LI1,EIF2AK2,EIF4EBP1,EPHA2,G3BP1,G3BP2,GPC6,HAX1,HDAC4,HSP90AA1,IDE,KAT2A,LDB2,MAPK9,MAPRE1,NAPB,NAV3,NECTIN1,NOP53,NPM1,NR1H2,PDCD6IP,PFN2,PIH1D1,PLEK2,PLK2,PMAIP1,PPFIA1,PRKAA1,PSMC5,PSRC1,RAB3GAP2,RAC1,RACK1,RAP1B,RIOK1,RIOK2,RP1,RPL13A,RPS3,RUNX1,SACS,SLIT2,SMPD3,SPHK1,SUMO1,TBC1D14,TBX20,TLR2,TMOD3,UBE2V2,UTP15,WDR43,ZMYND10 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 627 | 57 | AAAS,AADAT,ACBD6,ACOT7,ACOT9,ADK,ADORA2B,AGPAT5,AK2,APOBEC3A,APOBEC3D,BPGM,CASK,DLST,ECD,EFL1,EIF6,EPHA2,FAR1,GARS1,GFPT1,GFPT2,GNAI3,GNPDA1,GNPDA2,GPAT3,GTPBP1,HAAO,HDAC4,HK2,IMPAD1,KARS1,MTCO2P12,MTHFD1L,NADK,NAMPT,NANS,NME2,NT5C,NUDT1,NUP54,NUP58,NUP88,NUP93,NUP98,PDE4D,PFKP,PGAM1,PGM3,PID1,PMM2,PNKP,PNP,PRKAA1,SEC13,SLC35A3,UAP1 |
| GO_POSITIVE_REGULATION_OF_TELOMERASE_RNA_LOCALIZATION_TO_CAJAL_BODY | 0.0e+00 | 0.0e+00 | 1603 | 15 | 10 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,NOP10,RUVBL2,TCP1 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1603 | 391 | 43 | ADAMTS1,ANAPC5,ANXA1,ASNS,AURKA,CDK4,CNOT1,CNOT7,E2F7,EIF4EBP1,EPGN,EREG,EVI2B,EZH2,FGF8,FOSL1,GADD45A,GATA6,HES1,HSP90AB1,MEIOC,MNAT1,MSX1,NPM1,PAFAH1B1,PIWIL2,PLK2,PLK3,PLRG1,PRMT1,PSRC1,RAD23A,RAD51B,RHNO1,RPL23,RPL26,RPS15A,RPS6KB1,SMPD3,SPHK1,TFAP4,TGFA,TMOD3 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 0.0e+00 | 0.0e+00 | 1603 | 97 | 21 | CANX,IDE,PDIA3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,SEC13,SEC23A,SEC24A,SEC24D |
| GO_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 190 | 29 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CERS1,CHRAC1,CHTF8,HSP90AA1,HSP90AB1,LIG3,MAP3K4,MAPKAPK5,MYC,NIBAN2,NOP10,PNKP,POLD2,POLE4,POT1,PRIMPOL,RPS27A,SMPD3,TCP1,TENT4B,UBA52,WRN |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1603 | 973 | 75 | ABCC4,ABCC9,ANXA1,ANXA7,AREG,ASNS,ATG7,CBX3,CCL5,CDK4,CNOT1,CRY1,DDX18,DDX21,DHX36,DUOX2,DUSP6,EIF4EBP1,ESRRG,EZH2,FGF8,FHL2,FOSB,FOSL1,GCLC,GCLM,GNAI3,GRAMD1B,GRAMD1C,HAMP,HOMER2,HRH1,HSP90AB1,HTR7,KAT2A,KCTD6,KLF16,NAMPT,NPM1,NR1D1,NR1D2,NR1H2,PAK4,PANX1,PDE12,PDE4D,PDXP,PIM1,PMAIP1,PPP2R2A,PRKAA1,PRMT5,RAP1B,RGS4,RPS6KB1,RUNX1,RUVBL2,RWDD1,SHMT2,SLC16A1,SLIT2,SMAD5,STC2,TAF1,TFAP4,TLR2,TMEM38B,TNC,TOMM20,TYR,UBA5,UFM1,UFSP2,URI1,ZFP36 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1117 | 82 | AAAS,AADAT,ABHD10,ACBD6,ACOT7,ACOT9,ADAMTS9,ADK,AK2,ALG10B,ALG14,APOBEC3A,APOBEC3D,B4GALT3,BPGM,CANT1,CASK,CD44,CREM,DDOST,DLST,DPM1,DPM2,DSE,ECD,EFL1,EIF6,EPHA2,ERP44,FAR1,FUT2,FUT9,GFPT1,GFPT2,GNAI3,GNPDA1,GNPDA2,GPC6,GTPBP1,HBEGF,HDAC4,HK2,IMPAD1,LMAN1,MCFD2,MTCO2P12,NANS,NGLY1,NME2,NT5C,NUDT1,NUP54,NUP58,NUP88,NUP93,NUP98,NUS1,PDE4D,PFKP,PGAM1,PGM3,PHLDA1,PID1,PIGA,PIGL,PIM1,PMM2,PNP,PRKAA1,RPN1,SEC13,SEL1L,SERP1,SLC35A3,SLC35D2,SMPD3,ST3GAL4,SYVN1,TMEM106A,TMEM258,TYW5,UAP1 |
| GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 219 | 31 | ABCE1,CARMIL2,CCSAP,CIB1,DAP3,EIF5A2,ERAL1,ETF1,GADD45GIP1,GAK,KATNB1,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,NAPB,NAV3,PDXP,TMOD3,UPF1 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | 0.0e+00 | 0.0e+00 | 1603 | 233 | 32 | ATG7,CHCHD2,EIF4EBP1,ELOC,FAS,GATA6,MYC,NAMPT,NOP53,PLK3,PMAIP1,PRKAA1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,STC2,TBL2,TMBIM6,UBA52,UBQLN1 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 620 | 56 | ATF3,BOD1,C9orf72,CEP85,CIB1,CRKL,CRY1,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,GADD45A,GCLC,GTPBP4,IPO5,MFHAS1,MYC,N4BP1,NPM1,PAFAH1B1,PAQR3,PDE4D,PID1,PIH1D1,PNKP,PPP1R14B,PPP2CA,PRKAA1,PRKAR1B,PRNP,RACK1,RGS4,RPL11,RPL23,RPL5,RPS3,RTRAF,SLIT2,SMARCB1,SPRED1,SPRED2,SPRY2,SPRY4,SVBP,TAF1,TARDBP,TBC1D10C,TFAP4,TRIB2,TRIB3,U2AF2,UBASH3B,URI1,YWHAE,ZNF451 |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1603 | 1894 | 118 | AAAS,ADORA2B,AHCYL1,AIM2,AIMP1,ALG10B,ANKRD27,ANXA1,ANXA5,APBA1,ARIH2,BICD1,BRSK1,CAB39,CACNA1F,CASK,CBARP,CCL5,CD14,CDK16,CEP290,CIB1,CNST,CRACR2A,CRY1,DHX36,DNAJC27,DOC2A,DPH3,EIPR1,EMD,ENY2,EPB41,EPPIN,EPRS1,ERFE,FOXA2,GCLC,GOLPH3L,GRB10,HAMP,HAX1,HK2,HOMER2,IL15RA,IL4R,IPO5,ITPR1,KARS1,KCNG1,KCNG4,KCNQ5,LILRA5,LMAN1,MAP2K1,NADK,NAPB,NDUFAF2,NETO1,NMT1,NOLC1,NR1D1,NR1H2,NUP54,NUP58,NUS1,OAZ1,PANX1,PDCD5,PDCD6IP,PDE4D,PFN2,PID1,PIM1,PLK3,PMAIP1,PPID,PRKAA1,PRKAR1B,PRNP,RAB27A,RAB27B,RAB2B,RAC1,RACK1,RAP1B,RFX3,RGS4,RINT1,RIOK2,RPS6KB1,SEC24A,SELENOK,SELENOS,SERP1,SLC16A1,SLC1A2,SLC25A6,SLC9B2,SMPD3,SNAP25,SPHK1,STAC,STC2,SUMO1,TARDBP,TLR2,TMBIM6,TMC2,TMEM38B,TRIB3,TXN,UBASH3B,UBQLN1,XPO1,XPO5,YWHAE,ZFAND1 |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 752 | 63 | AAAS,AP3M2,AP3S2,APBA1,AURKA,BCCIP,BICD1,BORA,BRSK1,C10orf90,CCDC66,CCSAP,CEP85,CEP97,CFAP74,CIB1,DNAH14,DNAH9,DYNC1LI2,DYNC2LI1,GADD45A,INTS13,KAT2A,KATNA1,KATNB1,LRPPRC,MAATS1,MAPRE1,MARK2,MARK3,MREG,MSTO1,NAV3,NPM1,NUBP1,PAFAH1B1,PDCD6IP,PLK2,PLK3,PRKAA1,PSRC1,RAB27B,RAC1,RFX3,RNF19A,RP1,RPGR,RPS3,RTTN,SAPCD2,SLC16A1,SPAG1,SPRY2,SRRD,SSNA1,TRIM36,TUBD1,TUBE1,UXT,XPO1,ZMYND10,ZNF207,ZW10 |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEOPLASM | 0.0e+00 | 0.0e+00 | 1603 | 12 | 9 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,NOP53,TCP1 |
| GO_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 795 | 65 | ASF1A,AURKA,BRPF1,BUD23,CBX3,CENPN,CHRAC1,COPRS,CXXC1,ELK4,ENY2,EZH2,FOXA2,GFI1,GTF2B,H2AC15,H2AC17,H2AC20,H2AC21,H2BC11,H2BC12,H2BC13,H2BC8,H3C14,H4C2,H4C3,H4C4,HDAC4,HMGA1,JADE3,KAT2A,KAT8,MBD1,MIER2,MORF4L2,MRGBP,MYC,NAA50,NPM1,PCGF6,PHF19,PHF20,PIH1D1,PIWIL1,PIWIL2,POLE4,PPHLN1,PPM1D,PRDM14,PRKAA1,PRMT1,PRMT5,PSME4,RCCD1,RNF2,RUVBL2,SETD3,SFMBT1,SGF29,SMARCB1,SS18L1,TAF1,TAF6,USP15,ZNF451 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME | 0.0e+00 | 0.0e+00 | 1603 | 27 | 12 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,PIH1D1,POT1,RUVBL2,SGF29,TCP1 |
| GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1603 | 214 | 30 | AURKA,BRSK1,CDK4,CEP290,HSP90AA1,HUS1,MAPRE1,NBN,NEDD1,NOP53,NPM1,PAFAH1B1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAD51B,RINT1,SSNA1,YWHAE |
| GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 0.0e+00 | 0.0e+00 | 1603 | 162 | 26 | ASNS,ATF3,CANX,COPS5,CREB3,CTH,CXXC1,DDIT3,DERL1,DNAJB9,EIF2AK2,EIF2S1,FKBP14,GFPT1,GOSR2,HERPUD1,HSPA13,PDIA6,RACK1,SELENOS,SERP1,SRPRA,STC2,SYVN1,TBL2,TMBIM6 |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1603 | 547 | 51 | ABCE1,ATG7,CARMIL2,CCSAP,CD44,CDC37,CIB1,CSNK1A1,DAP3,DFFA,DICER1,EIF5A2,ERAL1,ETF1,GADD45GIP1,GAK,HAX1,HK2,HMGA1,KATNB1,MARK2,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF,MYC,NAPB,NAV3,PAFAH1B1,PAM16,PDXP,PELO,PLK3,RPL23,SMARCB1,TMOD3,UBQLN1,UPF1,VTA1,ZFAND1 |
| GO_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 286 | 35 | AAAS,ABCE1,DDX19B,DDX39A,DYNC2LI1,EIF6,ENY2,EXOC3L2,GPC6,MAGOH,NETO1,NMD3,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,RIOK2,RPGR,RPS15,SDAD1,SEC13,SNAP25,SRSF1,SRSF3,SRSF7,SSNA1,THOC6,U2AF1,U2AF2,UPF1,WDR33,XPO1,XPOT |
| GO_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 347 | 39 | ANAPC5,ASF1A,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC23,CDC26,DHX36,GFI1,GNL3,HMGA1,KAT2A,MAP3K4,MAPKAPK5,MNAT1,MYC,NBN,PHF19,PIH1D1,PIWIL2,PNKP,POT1,PPHLN1,RIOK2,RMI2,RUVBL2,SHCBP1L,SMARCB1,TCP1,TENT4B,TEX14,UPF1,ZNF207,ZNF451,ZW10 |
| GO_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 0.0e+00 | 1603 | 769 | 63 | ADORA2B,ATF3,CCL20,CCL5,CD44,CIB1,COPS5,CRKL,DNAJC27,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EPGN,EPHA2,EZH2,FAS,FGF8,FLT1,GADD45A,GDF15,INHBE,IRAK2,KARS1,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MFHAS1,MYC,PAFAH1B1,PAQR3,PDGFA,PELI2,PPP2CA,PRKAA1,PRMT1,PRMT5,RAP1B,RELL1,RGS4,RPS27A,RPS3,SEMA3A,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,STK40,TBC1D10C,TGFA,TMEM106A,TRIB2,TRIB3,UBA52,VRK2 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1603 | 603 | 54 | AEN,ATF3,BCL10,CD14,CD44,CHAC1,CIB1,CREB3,CSNK2A1,CTH,DAP3,DDIT3,DDX47,EDA2R,EPHA2,FAS,GCLC,GCLM,GNAI3,HERPUD1,ITPR1,MAPK9,MCL1,MSX1,NBN,NLE1,NMT1,PAM16,PDCD5,PDIA3,PIH1D1,PMAIP1,RACK1,RAD9A,RFFL,RPL11,RPL26,RPS3,RPS6KB1,SELENOK,SELENOS,SGK3,SIAH2,SYVN1,TFAP4,TMBIM6,TMEM161A,TPT1,TRAP1,TRIB3,UBQLN1,URI1,YBX3,YWHAE |
| GO_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 1603 | 551 | 51 | ASF1A,BCCIP,CEBPG,CIB1,COPS5,GADD45A,H4C2,H4C3,H4C4,HMGA1,HUS1,LIG3,MEIOC,MMS19,MNAT1,MORF4L2,MUTYH,NBN,NOP53,NPM1,NUDT1,PNKP,POLD2,POLR2C,POLR2H,POLR2J,PPIE,PRIMPOL,PSMD14,PSME4,RAD23A,RAD23B,RAD51B,RAD9A,RHNO1,RMI2,RPS27A,RPS3,RUVBL2,SHLD3,SUMO1,TCEA1,TDP1,TMEM161A,UBA52,UBE2V2,UPF1,WDR33,WRN,XRCC6,ZRANB3 |
| GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 431 | 44 | ARIH1,ARIH2,ATG7,AURKA,C9orf72,CDC37,CNOT1,CNOT7,CSNK1A1,CSNK2A1,DHX36,FBXL5,GCLC,GNAI3,GTPBP1,HERPUD1,HK2,HSP90AA1,IDE,MAPK9,METTL16,MTDH,NOP53,OAZ1,PIM2,PLK2,PLK3,PRKAA1,RAB3GAP2,RACK1,RAD23A,RNF19A,SESN2,SMURF2,SPTLC2,SUMO1,TAF1,TBK1,TRIB2,TRIB3,UBE2V2,UBQLN1,UPF1,ZFP36 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 366 | 40 | ARIH1,ARIH2,ATG7,AURKA,C9orf72,CDC37,CNOT1,CNOT7,CSNK1A1,DHX36,FBXL5,GCLC,GNAI3,GTPBP1,HERPUD1,HK2,HSP90AA1,MAPK9,METTL16,MTDH,NOP53,PIM2,PLK2,PLK3,PRKAA1,RAB3GAP2,RACK1,RAD23A,RNF19A,SESN2,SPTLC2,SUMO1,TAF1,TBK1,TRIB2,TRIB3,UBE2V2,UBQLN1,UPF1,ZFP36 |
| GO_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1603 | 85 | 19 | DHX36,EIF2AK2,HES1,PDCD2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RUNX1 |
| GO_NCRNA_TRANSCRIPTION | 0.0e+00 | 0.0e+00 | 1603 | 107 | 21 | GTF2B,GTF2E2,INTS10,INTS13,INTS4,INTS6,MARS1,NIFK,NOP53,PIH1D1,POLR1E,POLR2C,POLR2H,POLR2J,SMARCB1,SNAPC1,SNAPC2,TAF6,TBP,ZC3H8,ZNF143 |
| GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 353 | 39 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CEBPG,CERS1,CHTF8,DFFA,DHX36,GNL3,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,MMS19,MYC,NBN,NIBAN2,NPM1,PAM16,PNKP,POT1,PRDM14,PRMT5,RMI2,RPS3,SHLD3,TCP1,TENT4B,TFRC,TMEM161A,UBE2V2,UPF1,WRN,ZNF91,ZRANB3 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1670 | 106 | ABCE1,ADORA2B,AGO3,AIM2,ANKRD54,ANXA1,BCL10,BTLA,CACNA1F,CCL20,CCL5,CD14,CD320,CD8B2,CDC37,CFP,CIB1,CNOT7,CREB3,CRKL,DDX21,DHX36,DMBT1,EIF2AK2,EIF2B2,EIF6,EREG,EVI2B,FBXO38,GFI1,H3C14,H4C2,H4C3,H4C4,HAX1,HES1,HSP90AA1,HSP90AB1,ICAM3,IFNGR2,IL23A,IL4R,IRAK2,KARS1,KAT2A,KLF10,MAPK9,MAPKAPK3,MASP2,MFHAS1,MYC,NBL1,NCR3LG1,NME2,NOP53,NR1D1,NR1H2,OTULIN,PDCD2,PDE4D,PIM1,PNP,POLR3D,PRMT1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RHEX,RPS19,RPS27A,RPS3,RUNX1,SELENOK,SELENOS,SHLD3,SLC9B2,SLIT2,SMPD3,SPHK1,SUMO1,TBC1D10C,TBK1,TFRC,TLR2,TMBIM6,TRAF3,UBA52,UBASH3B,UBE2D2,UBQLN1,XRCC6,ZC3H8,ZFP36 |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1603 | 542 | 50 | ADGRG3,ATF3,CD44,CDC34,CIB1,CREB3,DDIT3,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EPHA2,FHL2,HERPUD1,HOMER2,ITPR1,MAPKAPK5,MARK3,MCL1,MYC,NOP53,NR1D1,OTUD7A,PAFAH1B1,PAQR3,PDE4D,PPP2CA,PRKAA1,PRNP,RACK1,RFFL,RGS4,SELENOS,SESN2,SLIT2,SPRED1,SPRED2,SPRY2,SPRY4,SYVN1,TBC1D10C,TMBIM6,TMEM161A,TPT1,TRAP1,TRIB3,UBR1,URI1,YBX3 |
| GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE | 0.0e+00 | 0.0e+00 | 1603 | 51 | 15 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,GNL3,MAP3K4,MAPKAPK5,NBN,PNKP,POT1,TCP1 |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1146 | 81 | ADORA2B,AREG,BCAR3,BCL10,BORA,CAB39,CCL20,CCL5,CD44,CIB1,CRKL,DNAJC27,DUSP12,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EPGN,EREG,EZH2,FAS,FGF8,FLT1,GADD45A,GDF15,HAX1,HBEGF,HES1,HRH1,HSP90AA1,HSP90AB1,IL23A,INHBE,IRAK2,KARS1,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MFHAS1,MNAT1,MOB2,MTCO2P12,NBN,NPM1,PAK4,PDGFA,PELI2,PFN2,PID1,PIH1D1,PPP2CA,PRKAA1,PRKAR1B,PRMT1,PRNP,PRR5,PRRC1,PSRC1,RAC1,RACK1,RAP1B,RELL1,RPLP1,RPS27A,RPS3,SEMA3A,SPHK1,SPRY2,TBK1,TGFA,TMEM106A,TXN,UBA52,WDFY2,XRCC6 |
| GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1603 | 408 | 42 | ATF3,BCL10,CD44,CREB3,CSNK2A1,CTH,DDIT3,FAS,GCLC,GCLM,GNAI3,HERPUD1,MAPK9,MCL1,MSX1,NLE1,NMT1,PAM16,PDCD5,PDIA3,PIH1D1,PMAIP1,RACK1,RAD9A,RFFL,RPL11,RPL26,RPS3,RPS6KB1,SELENOS,SGK3,SIAH2,SYVN1,TFAP4,TMBIM6,TMEM161A,TPT1,TRAP1,UBQLN1,URI1,YBX3,YWHAE |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1603 | 267 | 33 | AURKA,BRSK1,CDK4,CNOT1,CNOT7,E2F7,EZH2,GADD45A,HUS1,NBN,NOP53,PLK2,PLK3,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RINT1,RPL26,TEX14,ZNF207,ZW10 |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_TELOMERE | 0.0e+00 | 0.0e+00 | 1603 | 10 | 8 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,TCP1 |
| GO_SEXUAL_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1603 | 847 | 66 | AAAS,ACRBP,ADAMTS1,AURKA,CCDC36,CCT2,CCT3,CCT4,CCT5,CCT7,CCT8,CDK16,CIB1,CREM,CRKL,DDX20,DHX36,EIF2S2,EIF4H,EIF5A2,EREG,ETV5,FAM9C,FOSL1,GNPDA1,HDAC4,HERC4,IL4R,INTS13,MEIOC,OR7C1,PAFAH1B1,PAIP2,PAQR5,PGM3,PHC2,PIWIL1,PIWIL2,PLD6,PRDM14,PRDX4,PSME4,RAD23B,RFX2,RNF114,RNF2,RPS6,RPS6KB1,SFMBT1,SHCBP1L,SMAD5,SNU13,SPAG1,SPATA2,SPATA5,SPIN2A,TAF4B,TBP,TCP1,TEX14,TRIM36,USP42,WBP2NL,WDR33,XRN2,YBX3 |
| GO_NEGATIVE_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS | 0.0e+00 | 0.0e+00 | 1603 | 24 | 11 | DFFA,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,PAM16,RFFL |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION | 0.0e+00 | 0.0e+00 | 1603 | 14 | 9 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,GNL3,TCP1 |
| GO_RRNA_CONTAINING_RIBONUCLEOPROTEIN_COMPLEX_EXPORT_FROM_NUCLEUS | 0.0e+00 | 0.0e+00 | 1603 | 14 | 9 | ABCE1,EIF6,NMD3,NPM1,NUP88,RIOK2,RPS15,SDAD1,XPO1 |
| GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 0.0e+00 | 0.0e+00 | 1603 | 37 | 13 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,MAP3K4,MAPKAPK5,PNKP,POT1,TCP1 |
| GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 200 | 28 | AADAT,ALDH18A1,ALDH8A1,ASNS,BCAT1,BHMT2,BLMH,CTH,DLST,GCLC,GCLM,GFPT1,GFPT2,GLYATL1,GPT2,HAAO,IL4I1,MTR,MTRR,ODC1,PHGDH,PRDX4,PSAT1,PYCR1,SARS1,SHMT2,SMS,TYR |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 1603 | 1765 | 109 | ABCC9,ABCE1,ADORA2B,AEN,AIM2,AIMP1,ANXA1,APOBEC3A,APOBEC3D,ATG7,BCL10,C5orf30,CCL20,CCL5,CD14,CD44,CDC37,CEBPG,CFP,CNOT7,COTL1,CXCL2,CXCL3,DDX21,DHX36,DMBT1,DUOX2,EIF2AK2,EPHA2,EPPIN,EPRS1,EREG,FOSL1,G3BP1,G3BP2,GBP3,GBP6,GFI1,H2BC11,H2BC12,H2BC8,HAMP,HDAC4,HRH1,HSP90AB1,ICAM3,IFNGR2,IL23A,IL4R,IRAK2,KARS1,LEAP2,LIAS,LILRA5,MAPKAPK3,MASP2,MFHAS1,MT2A,NAMPT,NEUROD2,NOP53,NR1D1,NR1D2,NR1H2,OTULIN,PDE12,PMAIP1,POLR3D,PPP1R14B,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAB27A,RAC1,RPL13A,RPL30,RPL39,RPS19,RPS27A,RPS6KB1,SEC61A1,SELENOK,SELENOS,SHMT2,SLFN13,SPATA2,SPHK1,SUMO1,TBK1,TLR2,TMEM106A,TRAF3,TRIM11,TTC4,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_COFACTOR_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 449 | 44 | AADAT,ACBD6,ACOT7,ACOT9,AHCYL1,BHMT2,BOLA2B,CD320,CHAC1,CIAO1,COQ10B,COQ6,COX10,DLST,DUOX2,FAR1,GCLC,GCLM,GLO1,GLRX2,GSTM5,HAAO,HSP90AA1,IREB2,LIAS,METTL16,MMADHC,MMS19,MTCO2P12,MTHFD1L,MTHFD2,MTR,MTRR,NADK,NAMPT,NUBP1,NUBP2,PDXP,PRDX4,PSAT1,RAC1,SHMT2,SRRD,UBIAD1 |
| GO_REGULATION_OF_TELOMERE_MAINTENANCE | 0.0e+00 | 0.0e+00 | 1603 | 81 | 18 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,GNL3,MAP3K4,MAPKAPK5,MYC,NBN,PNKP,POT1,TCP1,TENT4B,UPF1 |
| GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 62 | 16 | OAZ1,ODC1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1 |
| GO_TELOMERASE_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 19 | 10 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,NOP10,RUVBL2,TCP1 |
| GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1603 | 433 | 43 | CCDC66,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,GNL3,H4C2,H4C3,H4C4,HAAO,HOMER2,HSP90AA1,HSP90AB1,HUS1,LDB2,MAP3K4,MAPKAPK5,MKS1,MYC,NBN,NOP10,PNKP,POC1B,POLD2,POLE4,POT1,PRDM14,PRIM2,PRKAA1,RAC1,RP1,TCP1,TENT4B,TFRC,TNFRSF11B,UBASH3B,UPF1,WRN,XRCC6 |
| GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1603 | 125 | 22 | ATF3,DDIT3,ELOC,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,SESN2,TAF1,TMBIM6,UBA52 |
| GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 522 | 48 | ABCE1,AIM2,BCL10,CCL5,CD14,CDC37,CNOT7,DMBT1,EREG,FBXO38,GFI1,HSP90AB1,ICAM3,IFNGR2,IL23A,IRAK2,MAPKAPK3,MFHAS1,NOP53,NR1D1,NR1H2,OTULIN,POLR3D,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS19,RPS27A,SELENOK,SUMO1,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 577 | 51 | ADORA2B,BCL10,BORA,CAB39,CCL5,CIB1,CRKL,DUSP12,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EREG,EZH2,FLT1,GADD45A,GDF15,HSP90AA1,HSP90AB1,IL23A,IRAK2,KARS1,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,MNAT1,NBN,NPM1,PAK4,PDGFA,PIH1D1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,PSRC1,RPLP1,RPS27A,RPS3,SPRY2,TGFA,TXN,UBA52,XRCC6 |
| GO_CELL_DIVISION | 0.0e+00 | 0.0e+00 | 1603 | 598 | 52 | ANAPC5,AURKA,BIN3,BOD1,BORA,CCDC124,CCSAP,CDC123,CDC23,CDC26,CDK4,CIB1,CSNK1A1,E2F7,EPB41,EREG,ETV5,EVI2B,FGF8,GNAI3,GNL3,INTS13,KATNA1,KATNB1,LIG3,MAPRE1,MITD1,MYC,NEDD1,NUDC,PAFAH1B1,PDCD6IP,PDGFA,PDXP,PELO,PLK2,PLK3,PSRC1,RACK1,RPS3,SAPCD2,SHCBP1L,SPOUT1,TENT4B,TEX14,TGFA,TIPIN,TRIM36,USP39,YBX1,ZNF207,ZW10 |
| GO_CELLULAR_KETONE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 248 | 31 | AADAT,ALDH8A1,ANXA1,COQ10B,COQ6,EIF6,ERFE,GLO1,KDSR,NMT1,NR1D1,NR1H2,OAZ1,ODC1,PRKAB2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,TRIB3,UBIAD1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1603 | 105 | 20 | AURKA,BRSK1,HUS1,NBN,NOP53,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RINT1 |
| GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 192 | 27 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CEBPG,CHTF8,DHX36,GNL3,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,MMS19,MYC,NBN,PNKP,POT1,RPS3,SHLD3,TCP1,TFRC,TMEM161A,UBE2V2,WRN |
| GO_GROWTH | 0.0e+00 | 0.0e+00 | 1603 | 990 | 72 | ANXA1,APBA1,AREG,ARIH2,ARMC10,AURKA,BIN3,C9orf72,CDH4,CDK11B,CDK4,CIB1,CPNE5,CRKL,CSNK2A1,DUSP6,EIF4H,EREG,EZH2,FGF8,FOXC2,FSTL4,GATA6,GDF15,GOLGA4,HAMP,HBEGF,HSP90AA1,HSP90AB1,ING1,KAT2A,KCTD6,MORF4L2,MRGBP,MSX1,MT2A,NBN,NET1,NPM1,NUBP1,OSGIN1,OSGIN2,PAFAH1B1,PAK4,PDE4D,PELO,PIM1,PPP2CA,PSRC1,RACK1,RAPH1,RGS4,RPS6KB1,RUVBL2,SEMA3A,SERP1,SESN2,SGK3,SLC1A2,SLIT2,SMPD3,SOCS7,SPHK1,SPRY2,STC2,STK40,TBX20,TMEM38B,TNC,URI1,WRN,YBX3 |
| GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1603 | 166 | 25 | AIM2,EDA2R,H2BC11,KARS1,OTULIN,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RFFL,SPATA2,SPHK1,TNFRSF11B,TRAF3 |
| GO_POSITIVE_REGULATION_OF_TRANSLATION | 0.0e+00 | 0.0e+00 | 1603 | 129 | 22 | CCL5,CDC123,CDK4,CNBP,DHX36,EIF2S3,EIF3C,EIF3D,EIF5A2,EIF6,NPM1,NSUN4,PIWIL2,RPL26,RPL30,RPL5,RPS4X,RPS6KB1,RPS9,SERP1,UPF3A,YBX3 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 252 | 31 | ARIH1,ARIH2,AURKA,CSNK1A1,CSNK2A1,FBXL5,FOXF2,GCLC,HERPUD1,HSP90AA1,HSP90AB1,MAPK9,N4BP1,NOP53,PLK2,PLK3,PSMD14,PSMF1,RACK1,RAD23A,RAD23B,RNF19A,RPL11,RPL23,RPL5,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 156 | 24 | CCL5,CDC123,CDK4,CNBP,DHX36,EIF2S3,EIF3C,EIF3D,EIF5A2,EIF6,NPM1,NSUN4,PIWIL2,RACK1,RPL26,RPL30,RPL5,RPS4X,RPS6KB1,RPS9,SERP1,SMPD3,UPF3A,YBX3 |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 553 | 49 | AAAS,AURKA,BCCIP,BICD1,BORA,BRSK1,C10orf90,CCDC66,CCSAP,CEP85,CEP97,CFAP74,CIB1,DYNC1LI2,GADD45A,INTS13,KAT2A,KATNA1,KATNB1,MAPRE1,MARK2,MARK3,MSTO1,NAV3,NPM1,NUBP1,PAFAH1B1,PDCD6IP,PLK2,PLK3,PRKAA1,PSRC1,RAC1,RNF19A,RP1,RPS3,RTTN,SAPCD2,SLC16A1,SPAG1,SPRY2,TRIM36,TUBD1,TUBE1,UXT,XPO1,ZMYND10,ZNF207,ZW10 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1825 | 110 | ADM2,ADORA2B,AIM2,AMIGO2,ANKRD27,ANKRD54,ANXA1,AURKA,BCL10,BSCL2,CD14,CDH4,CEBPG,CIB1,CPNE5,CRKL,CTH,DDIT3,DDX21,DHX36,DICER1,DLX2,DOCK5,EIF2AK2,EREG,ESRRG,ETV5,EVI2B,EZH2,FBXO38,FGF8,FLT1,FOXA2,FOXC2,GATA6,GOLGA4,GPR3,GRB10,HAMP,HAX1,HBEGF,HDAC4,HES1,HK2,HRH1,IL23A,IL4R,KARS1,KAT2A,KATNB1,KLF10,LILRA5,MAP2K1,MARK2,MOB2,MTDH,MYC,NBL1,NETO1,NEUROD2,NIBAN2,NME2,NOP53,NR1H2,NUS1,PAFAH1B1,PAK4,PANX1,PDCD2,PDE4D,PDGFA,PIM1,PLK2,PNP,POLR2H,POLR3D,PRDM14,PRKAA1,PRKAB2,PRMT1,PRMT5,RACK1,RBM19,RFX3,RGS4,RHEB,RHEX,RPS19,RPS3,RPS6KB1,RUNX1,SELENOK,SEMA3A,SERP1,SHLD3,SLC9B2,SLIT2,SMAD5,SMURF2,SPHK1,SS18L1,SUCO,TBK1,TBX20,TFRC,TLR2,UBE2V2,XRCC6,YBX3,ZNF609 |
| GO_EXOCYTOSIS | 0.0e+00 | 0.0e+00 | 1603 | 900 | 67 | ABCC4,ADGRG3,ADORA2B,ANXA1,ANXA5,APBA1,ATAD3B,ATG7,ATP11B,CAB39,CANT1,CASK,CBARP,CCL5,CCT2,CCT8,CD14,CD44,CDK16,CEP290,CFP,COPB1,COPS5,COTL1,CRACR2A,DDOST,DOC2A,EEF1A1,ERP44,EXOC3L2,GTPBP2,HSP90AA1,HSP90AB1,IL4R,ILF2,NAPB,NME2,OLA1,PDCD6IP,PDGFA,PFN2,PGAM1,PNP,PPIE,PRDX4,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAB27B,RAB2B,RABEPK,RAC1,RAP1B,SMPD3,SNAP25,STX19,TBC1D10C,TLR2,TXNDC5,XRCC6 |
| GO_REGULATION_OF_BINDING | 0.0e+00 | 0.0e+00 | 1603 | 381 | 39 | AURKA,C9orf72,CEBPG,CSNK1A1,DDIT3,DERL1,DPH3,EIF2S1,EIF3C,EIF3D,EPB41,GTF2B,GTPBP4,HDAC4,HES1,HOXA3,HSP90AB1,MAP2K1,MAPRE1,MARK2,MARK3,MDFI,MITD1,MSX1,NIBAN2,NMD3,PIM2,PLK2,PPP2CA,RPL11,RUVBL2,SUMO1,TAF1,TEX14,TFAP4,TMBIM6,TRIB3,TXN,UBASH3B |
| GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 67 | 16 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CHTF8,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,MYC,PNKP,POT1,TCP1 |
| GO_MATURATION_OF_LSU_RRNA | 0.0e+00 | 0.0e+00 | 1603 | 21 | 10 | BOP1,DDX18,GTPBP4,MRPL1,RPF2,RPL10A,RPL35,RPL7,RSL1D1,SNU13 |
| GO_POSITIVE_REGULATION_OF_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 98 | 19 | ARIH1,ARIH2,AURKA,CSNK1A1,GCLC,HERPUD1,MAPK9,NOP53,PLK2,PLK3,RACK1,RAD23A,RNF19A,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_HYPOXIA | 0.0e+00 | 0.0e+00 | 1603 | 77 | 17 | ELOC,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,UBA52 |
| GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 185 | 26 | ARIH1,ARIH2,AURKA,CSNK1A1,FOXF2,GCLC,HERPUD1,HSP90AB1,MAPK9,N4BP1,NOP53,PLK2,PLK3,PSMD14,PSMF1,RACK1,RAD23A,RAD23B,RNF19A,RPL11,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_RESPONSE_TO_OXIDATIVE_STRESS | 0.0e+00 | 0.0e+00 | 1603 | 453 | 43 | ANXA1,AREG,ATG7,DUOX2,EIF2S1,ETV5,EZH2,FGF8,FOSL1,GCLC,GCLM,GLRX2,LIAS,LONP1,MAPK9,MCL1,MTF1,MTR,NET1,NME2,NUDT1,PLK3,PNKP,PRDX4,PRKAA1,PRNP,PYCR1,RACK1,RBM11,RPS3,RWDD1,SELENOK,SELENOS,SESN2,SMPD3,SRXN1,STC2,TMEM161A,TRAP1,TXN,UBQLN1,VRK2,WRN |
| GO_CELLULAR_RESPONSE_TO_RADIATION | 0.0e+00 | 0.0e+00 | 1603 | 187 | 26 | CERS1,CRY1,DHX36,EEF1D,EIF2S1,FNTB,GADD45A,HAMP,HUS1,MYC,N4BP1,NAMPT,NET1,NMT1,NPM1,PPID,RAD9A,RHNO1,RP1,RPL26,RUVBL2,TAF1,TENT2,TMEM161A,WRN,XRCC6 |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 526 | 47 | ABCC9,ADORA2B,ASNS,ATF3,ATG7,BCL10,COX4I1,DDIT3,EIF2AK2,EIF2S1,EIF4EBP1,FAS,FOSL1,FOXA2,GCLC,GCLM,GDF15,GLRX2,HAMP,KAT2A,KLF10,LARS1,MARS1,MAX,NAMPT,NOCT,NUDT1,PANX1,PDXP,PIM1,PMAIP1,PPM1D,PRKAA1,RPS19,RPS6KB1,SESN2,SLC16A1,SLC1A2,STC2,TAF1,TBL2,TMBIM6,TNC,TNFRSF11B,TYR,WRN,ZFP36 |
| GO_RESPONSE_TO_GROWTH_FACTOR | 0.0e+00 | 0.0e+00 | 1603 | 732 | 58 | ANXA1,CASK,CCL5,CD44,CDC34,CIB1,CRKL,DUSP6,DYNC1LI2,EEF1A1,EMD,EPHA2,FAM83G,FGF8,FLT1,GATA6,GCLC,GCLM,GDF15,GRB10,HES1,HSP90AB1,IER2,KAT2A,MARS1,MSX1,MYC,NBL1,NIBAN2,NUS1,PDCD5,PELO,POLR2C,POLR2H,POLR2J,PRDM14,RACK1,RGMB,RPL8,RPS27A,RPS6KB1,SLIT2,SMAD5,SMPD3,SMURF2,SPHK1,SPRED1,SPRED2,SPRY2,SPRY4,TNC,TRIM33,UBA52,URI1,USP15,ZCCHC18,ZFP36,ZNF451 |
| GO_INTERLEUKIN_1_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1603 | 100 | 19 | IRAK2,PELI2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,UBA52,VRK2 |
| GO_MITOCHONDRIAL_TRANSLATIONAL_TERMINATION | 0.0e+00 | 0.0e+00 | 1603 | 89 | 18 | DAP3,ERAL1,GADD45GIP1,MRPL1,MRPL14,MRPL17,MRPL19,MRPL2,MRPL22,MRPL32,MRPL44,MRPL47,MRPL48,MRPL49,MRPL55,MRPS5,MRPS6,MRRF |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1033 | 73 | AAAS,AADAT,ACBD6,ACOT7,ACOT9,ADK,ADORA2B,AGPAT5,AK2,BPGM,CASK,CSNK2A1,DLST,DPM1,DPM2,ECD,EFL1,EIF6,EPHA2,FAM126A,FAR1,FLT1,GARS1,GATA6,GFPT1,GFPT2,GNAI3,GPAT3,GTPBP1,HAAO,HDAC4,HDHD5,HK2,HRH1,IMPA1,IMPAD1,KARS1,MFSD2A,MTCO2P12,NADK,NAMPT,NME2,NT5C,NUDT1,NUP54,NUP58,NUP88,NUP93,NUP98,NUS1,PAFAH1B1,PDE4D,PDGFA,PDXP,PFKP,PGAM1,PGM3,PI4KAP1,PID1,PIGA,PIGL,PIP4P1,PLD6,PNKP,PNP,PRKAA1,PROCA1,SEC13,SELENOI,SMPD3,SOCS7,SPTLC2,TMEM38B |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 1287 | 85 | ABCE1,AGAP7P,AGAP9,AHSA1,AIM2,ANKRD27,ANXA1,ARF4,ARFGAP3,ARHGAP18,ARHGAP33,ARHGEF1,ARL1,BCL10,BICD1,BLID,BOD1,CCL20,CCL5,CD44,CLPX,CNST,CRKL,CSNK2A1,DFFA,DOCK5,EIF2AK2,EPHA2,EPPIN,EZH2,FAS,FLT1,HERPUD1,HSP90AB1,IPO5,KARS1,LARS1,MNAT1,MYC,NET1,NLE1,NPM1,NR1H2,PAFAH1B1,PAM16,PDCD2,PDCD5,PFN2,PIH1D1,PMAIP1,POT1,PPP1R14B,PPP1R16A,PPP2R2A,PRNP,PSMD14,PSME4,PSMF1,RAB3GAP2,RACK1,RAP1GDS1,RAPGEF6,RFFL,RGPD5,RGS17,RGS4,RGS5,RPS3,SEC23A,SERPINB5,SERPINI2,SIAH2,SLIT2,SPRED1,SPRY2,TBC1D10C,TBC1D14,TCEA1,TFAP4,TMBIM6,TRAPPC6B,URI1,VCPKMT,WRN,YWHAE |
| GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 388 | 39 | ARIH1,ARIH2,ATG7,AURKA,CSNK1A1,CSNK2A1,EEF1A1,FBXL5,FOXF2,GCLC,HERPUD1,HSP90AA1,HSP90AB1,IDE,MAPK9,N4BP1,NOP53,OAZ1,ODC1,PLK2,PLK3,PSMD14,PSMD3,PSMF1,RACK1,RAD23A,RAD23B,RNF19A,RPL11,RPL23,RPL5,SMURF2,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1,XPO1 |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1016 | 72 | AAAS,ACRBP,ADAMTS1,AURKA,CCDC36,CCT2,CCT3,CCT4,CCT5,CCT7,CCT8,CDK16,CIB1,CREM,CRKL,DDX20,DHX36,EIF2S2,EIF4H,EIF5A2,EREG,ETV5,FAM9C,FOSB,FOSL1,GNPDA1,HDAC4,HERC4,IL4R,INTS13,MAFF,MEIOC,NAMPT,OR7C1,PAFAH1B1,PAIP2,PAQR5,PGM3,PHC2,PIWIL1,PIWIL2,PLD6,PRDM14,PRDX4,PSME4,RAD23B,RFX2,RNF114,RNF2,RPL29,RPS6,RPS6KB1,SFMBT1,SHCBP1L,SMAD5,SMURF2,SNU13,SPAG1,SPATA2,SPATA5,SPIN2A,STC2,TAF4B,TBP,TCP1,TEX14,TRIM36,USP42,WBP2NL,WDR33,XRN2,YBX3 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME | 0.0e+00 | 0.0e+00 | 1603 | 12 | 8 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,TCP1 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1603 | 1163 | 79 | ABI2,ADAMTS9,ADM2,ANKRD27,ANXA1,ANXA7,AP1AR,ARHGAP18,ARHGAP33,BRSK1,CD44,CDH4,CFDP1,CIB1,CPNE5,CRKL,DHX36,DNMBP,DOCK5,EPB41,EPHA2,ETV5,FGF8,FLT1,FMNL2,FOXA2,FOXC2,FSTL4,GATA6,GDF15,GOLGA4,GPC6,HES1,HK2,IL4R,MAP2K1,MARK2,MKS1,MSX1,MTDH,MYC,NIBAN2,PAFAH1B1,PAK4,PDGFA,PID1,PIM1,PLD6,PLK2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RACK1,RUNX1,SAPCD2,SARS1,SEMA3A,SLIT2,SMURF2,SPHK1,SPRED1,SPRY2,SS18L1,STRIP2,SYNE3,TNFRSF11B,ZMYM5 |
| GO_MEMBRANE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 875 | 65 | ANKRD27,ANXA1,ANXA7,APOO,AREG,ARFGAP3,ATG7,ATL1,ATP11B,BAIAP2L2,BANF1,BIN3,CRKL,EMD,EPGN,EPS15L1,EREG,ETV5,GAK,GCLC,GET4,GNAI3,GOLPH3L,GOSR2,HBEGF,HK2,HSP90AA1,HSPA4,IMMT,LMAN1,M6PR,MCFD2,MITD1,NECAP1,NMT1,NUP93,PAFAH1B1,PDCD5,PDCD6IP,PMAIP1,PPP2CA,PPP2R2A,RAC1,RILPL1,RPS27A,SEC13,SEC23A,SEC24A,SEC24D,SERP1,SNAP25,SPHK1,STX19,TARDBP,TFG,TFRC,TGFA,TIMM13,TIMM9,TMED9,TOMM20,TRAPPC6B,UBA52,UBL4A,YWHAE |
| GO_REGULATION_OF_HEMOPOIESIS | 0.0e+00 | 0.0e+00 | 1603 | 477 | 44 | AGO3,ANKRD54,ANXA1,CIB1,DHX36,EIF2AK2,EIF6,EVI2B,H3C14,H4C2,H4C3,H4C4,HAX1,HES1,IL23A,IL4R,KAT2A,KLF10,MYC,NME2,PDCD2,PIM1,PNP,PRMT1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RHEX,RUNX1,SLC9B2,UBASH3B,ZC3H8,ZFP36 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 326 | 35 | ARIH2,BICD1,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CEP290,CIB1,CNST,EMD,EPB41,EPHA2,GNL3,HSP90AB1,IPO5,NMD3,NMT1,NPM1,OAZ1,PDCD5,PLK3,PMAIP1,PRKAA1,PRNP,RACK1,RIOK2,SESN2,STAC,TARDBP,TCP1,YWHAE,ZFAND1 |
| GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_ENDONUCLEOLYTIC | 0.0e+00 | 0.0e+00 | 1603 | 71 | 16 | ABT1,AGO3,BOP1,DICER1,EDC3,MRPL44,NOB1,NOP14,PIWIL1,PIWIL2,RPP30,RPP40,RPS21,SLFN13,TSN,UTP23 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1603 | 1545 | 96 | ABCC4,ABI2,ANKRD27,AREG,ARF4,ARHGAP33,ARL13B,ATL1,AURKA,BBIP1,BIN3,BRSK1,C5orf30,C9orf72,CARMIL2,CCDC66,CD44,CDH4,CDK16,CEP290,CEP97,CFAP74,CIB1,CPNE5,CRKL,DHX36,DICER1,DNAH9,DYNC2LI1,EMP1,EPHA2,EZH2,FAM92B,FBXO38,FGF8,FSTL4,GAK,GFI1,GOLGA4,GRB10,HDAC4,HES1,HSP90AA1,HSP90AB1,KAT2A,KATNB1,KIRREL3,MAP2K1,MAPRE1,MARK2,MKS1,MOB2,MTR,NAV3,NBL1,NECTIN1,NEDD1,NIBAN2,NME2,NUBP1,NUBP2,PAFAH1B1,PAK4,PAQR3,PDGFA,PFN2,PHGDH,PLEK2,PLK2,POC1B,PRMT1,PRNP,RAC1,RAPGEF6,RAPH1,RFX2,RFX3,RP1,RPGR,RPL24,RTTN,SEMA3A,SLIT2,SNAP25,SPAG1,SPATA13,SPRY2,SS18L1,SSNA1,TMEM216,TNC,TUBD1,UBE2V2,VAX1,YWHAE,ZMYND10 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 823 | 62 | ABCE1,ANXA1,ANXA5,BICD1,BOD1,CD44,CEP85,CERS1,CIB1,CNST,CSNK2A1,DFFA,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EPPIN,FOXA2,GADD45A,GFI1,GNAI3,HERPUD1,IPO5,MNAT1,MTRR,NLE1,NPM1,OAZ1,PAM16,PAQR3,PIH1D1,POT1,PPP1R14B,PPP2CA,PRKAR1B,PRNP,PSMF1,RACK1,RFFL,RGS4,RPL11,RPL23,RPL5,RTRAF,SERPINB5,SERPINI2,SIAH2,SLIT2,SPRED1,SPRED2,SPRY2,SPRY4,TFAP4,TMBIM6,TRIB2,TRIB3,UBASH3B,URI1,VCPKMT,YWHAE,ZFP36 |
| GO_RESPONSE_TO_INTERLEUKIN_1 | 0.0e+00 | 0.0e+00 | 1603 | 207 | 27 | ANXA1,CCL20,CCL5,GBP3,GCLC,HDAC4,IRAK2,NR1D1,PELI2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,UBA52,UPF1,VRK2 |
| GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 0.0e+00 | 0.0e+00 | 1603 | 537 | 47 | AP1AR,AP3M2,AP3S2,AREG,ARFGAP3,BCCIP,BOD1,C17orf75,CDC23,CDK16,DDIT3,ENY2,FOXA2,GOSR2,ITPR1,KATNB1,LMAN1,MCFD2,MEIOC,MREG,NADK,NDUFAF2,NR1D1,PAFAH1B1,PDE4D,PRNP,PSRC1,RAB27A,RAB27B,RAC1,SAPCD2,SEC13,SEC23A,SEC24A,SEC24D,SLC9B2,SPRY2,STARD3NL,TERB2,TFG,TGFA,TMBIM6,TMED9,TMEM38B,TRAPPC6B,UBASH3B,ZW10 |
| GO_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1603 | 166 | 24 | AGPAT5,ARL11,C12orf29,DHX36,EIF2AK2,HES1,PDCD2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RUNX1,SMPD3,TENT2 |
| GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 0.0e+00 | 0.0e+00 | 1603 | 82 | 17 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,NOP10,PNKP,POT1,TCP1,TENT4B |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 0.0e+00 | 0.0e+00 | 1603 | 650 | 53 | ADGRG3,ADORA2B,ATAD3B,ATG7,ATP11B,BATF3,CAB39,CANT1,CCL5,CCT2,CCT8,CD14,CD44,CEP290,CFP,COPB1,COTL1,CRACR2A,DDOST,EEF1A1,ERP44,HSP90AA1,HSP90AB1,IL4R,ILF2,KARS1,MFHAS1,NAMPT,NME2,NR1D1,PGAM1,PNP,PPIE,PRDX4,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAC1,RAP1B,SNAP25,SPHK1,TBC1D10C,TLR2,TMEM106A,TXNDC5,XRCC6 |
| GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 72 | 16 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,NOP10,PNKP,POT1,TCP1,TENT4B |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 1603 | 614 | 51 | ANXA1,ATG7,CBX3,CCL5,CDK4,CNOT1,CRY1,DDX18,EIF4EBP1,ESRRG,EZH2,FHL2,GCLC,GCLM,GNAI3,GRAMD1B,GRAMD1C,HAMP,HRH1,HSP90AB1,HTR7,KCTD6,KLF16,NPM1,NR1D1,NR1D2,NR1H2,PAK4,PDE12,PDE4D,PDXP,PIM1,PRMT5,RAP1B,RGS4,RPS6KB1,RUNX1,RUVBL2,RWDD1,SHMT2,SLC16A1,SMAD5,TAF1,TFAP4,TMEM38B,TNC,UBA5,UFM1,UFSP2,URI1,ZFP36 |
| GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1603 | 141 | 22 | BRSK1,FOXF2,GPC6,MKS1,PAFAH1B1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SAPCD2,SMURF2 |
| GO_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 433 | 41 | ADGRG3,AIM2,BCL10,BUD31,CEBPG,CIB1,COPS5,CTH,DDIT3,EDA2R,EIF2AK2,EZH2,FOSL1,FOXA2,G3BP2,GFI1,HDAC4,IRAK2,MAPK9,MDFI,MTDH,NEUROD2,NPM1,OTULIN,PIM1,PRNP,PSMA6,RHEBL1,RNF2,RPS27A,RPS3,RWDD1,SGK3,SMARCB1,SPHK1,SUMO1,TAF1,TLR2,TRAF3,UBA52,ZIC2 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1603 | 1665 | 101 | ADORA2B,AGO3,AIMP1,AMER3,ANXA1,ANXA5,APBA1,AREG,BRSK1,CASK,CCL20,CCL5,CDK16,CRKL,CRY1,CSNK1A1,CSNK1G3,CSNK2A1,DDIT3,DLGAP1,DOC2A,EMD,ENY2,EREG,ETV5,FOXA2,G3BP1,GABRA2,GDF15,GPC6,GRB10,HES1,HMGXB4,HRH1,HTR7,ITPR1,KAT2A,KLF10,MARK2,MDFI,MKS1,NADK,NAMPT,NAPB,NDUFAF2,NETO1,NEUROD2,NIBAN2,NLE1,NR1D1,OTULIN,PAFAH1B1,PAIP2,PANX1,PDGFA,PFN2,PLK2,PPFIA1,PPP2CA,PRKAA1,PRKAR1B,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RACK1,RAP1B,RFX3,RGS4,RNF19A,RPS27A,RUNX1,RUVBL2,SERP1,SIAH2,SLC16A1,SLC1A2,SLC25A6,SLC9B2,SMPD3,SMURF2,SNAP25,STX19,TARDBP,TFAP2C,TLR2,TMED1,TNC,UBA52 |
| GO_IMMUNE_EFFECTOR_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 1267 | 83 | ABCC9,ABCE1,ADGRG3,ADORA2B,AEN,AIM2,AIMP1,ANXA1,APOBEC3A,APOBEC3D,ATAD3B,ATG7,ATP11B,BCL10,CAB39,CANT1,CCT2,CCT8,CD14,CD44,CEBPG,CEP290,CFP,CNOT7,COPB1,COTL1,CRACR2A,DDOST,DDX21,DHX36,DMBT1,EEF1A1,EIF2AK2,ERP44,FBXO38,G3BP1,GBP3,HSP90AA1,HSP90AB1,IL23A,IL4R,ILF2,KARS1,MASP2,NBN,NME2,NOP53,PDE12,PGAM1,PMAIP1,PNP,POLR3D,PPIE,PRDX4,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAC1,RAP1B,RPS19,RPS6,SELENOK,SHLD3,SLFN13,SNAP25,TBC1D10C,TBK1,TFRC,TLR2,TMBIM6,TMEM98,TRAF3,TRIM11,TTC4,TXNDC5,XRCC6 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1603 | 400 | 39 | AIM2,BCL10,CCL5,CD14,DMBT1,EREG,FBXO38,GFI1,ICAM3,IRAK2,MAPKAPK3,MFHAS1,NOP53,NR1D1,OTULIN,POLR3D,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS19,RPS27A,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME | 0.0e+00 | 0.0e+00 | 1603 | 83 | 17 | BOD1,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,EZH2,GNL3,PIH1D1,POT1,PPHLN1,RUVBL2,SGF29,TCP1,ZW10 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1603 | 974 | 69 | ACRBP,ADAMTS1,ANXA1,AREG,AURKA,CCDC36,CDK16,CIB1,CREM,CRKL,DDX20,DHX36,E2F7,EIF2B2,EIF2S2,EIF5A2,EREG,ETV5,FAM9C,FGF8,FOSL1,FOXF2,GATA6,HERC4,HES1,HSP90AB1,MAP2K1,MAP3K4,MDFI,MEIOC,NUDT1,OR7C1,PAFAH1B1,PAIP2,PAQR5,PGM3,PHC2,PIWIL1,PIWIL2,PLD6,PRDM14,PRDX4,PSME4,RAD23B,RFX2,RNF114,RNF2,RPS6,RPS6KB1,RTCB,SEMA3A,SERPINB5,SFMBT1,SHCBP1L,SLIT2,SMAD5,SPATA2,SPATA5,STC2,TAF4,TAF4B,TBP,TFAP2C,TNC,USP42,WDR33,WDR77,XRN2,YBX3 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_TELOMERE | 0.0e+00 | 0.0e+00 | 1603 | 18 | 9 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,POT1,TCP1 |
| GO_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1603 | 735 | 57 | AIM2,ARIH1,ARIH2,AURKA,BCL10,BLID,CD44,CHAC1,CLPX,CSNK1A1,CSNK2A1,EPPIN,FAS,FOXF2,GCLC,HERPUD1,HSP90AB1,IDE,KARS1,MAPK9,MYC,N4BP1,NLE1,NOP53,NR1H2,PDCD2,PDCD5,PIH1D1,PLK2,PLK3,PMAIP1,PRNP,PSMD14,PSME4,PSMF1,RACK1,RAD23A,RAD23B,RFFL,RNF19A,RPL11,RPL23,RPL5,RPS3,SERPINB5,SERPINI2,SIAH2,SUMO1,TAF1,TFAP4,TMEM98,TRAF3,TRIB2,TRIB3,UBE2V2,UBQLN1,YWHAE |
| GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1603 | 107 | 19 | AURKA,CD44,CNOT1,CNOT7,E2F7,GADD45A,MSX1,NBN,NPM1,PLK2,PLK3,PMAIP1,PPM1D,PRMT1,RPL26,SESN2,SPRED1,SPRED2,TFAP4 |
| GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1603 | 338 | 35 | ADORA2B,CRKL,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EZH2,FLT1,GADD45A,GDF15,IRAK2,KARS1,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,PAQR3,PDGFA,PPP2CA,PRKAA1,RGS4,RPS27A,RPS3,SPRED1,SPRED2,SPRY2,SPRY4,TGFA,TRIB2,TRIB3,UBA52 |
| GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 1603 | 322 | 34 | AIM2,BCL10,CD14,DMBT1,GFI1,ICAM3,IRAK2,MAPKAPK3,MFHAS1,NOP53,NR1D1,OTULIN,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 0.0e+00 | 0.0e+00 | 1603 | 549 | 47 | ADGRG3,ADORA2B,ATAD3B,ATG7,ATP11B,CAB39,CANT1,CCT2,CCT8,CD14,CD44,CEP290,CFP,COPB1,COTL1,CRACR2A,DDOST,DDX21,DHX36,EEF1A1,ERP44,HSP90AA1,HSP90AB1,IL4R,ILF2,NME2,PGAM1,PNP,PPIE,PRDX4,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAC1,RAP1B,SNAP25,TBC1D10C,TLR2,TXNDC5,XRCC6 |
| GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1603 | 108 | 19 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CERS1,CHTF8,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,MYC,NIBAN2,PNKP,POT1,TCP1,TENT4B |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1603 | 459 | 42 | AIM2,ARIH2,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD14,CEP290,CIB1,CNST,DHX36,EMD,GOLPH3L,IL4R,IPO5,KARS1,LILRA5,NADK,NMT1,NR1H2,OAZ1,PANX1,PDCD5,PLK3,PMAIP1,PPID,PRKAA1,PRNP,RAC1,RACK1,RIOK2,SEC24A,SELENOK,SERP1,TARDBP,TCP1,TLR2,YWHAE,ZFAND1 |
| GO_TRNA_MODIFICATION | 0.0e+00 | 0.0e+00 | 1603 | 86 | 17 | AARS1,CTU1,DPH3,DUS4L,ELP2,METTL1,METTL2A,MTO1,PUSL1,QTRT1,QTRT2,THG1L,THUMPD3,TRIT1,TRMO,TRMT61A,TYW5 |
| GO_RESPONSE_TO_OXYGEN_LEVELS | 0.0e+00 | 0.0e+00 | 1603 | 391 | 38 | APOLD1,ATG7,CDK4,CHCHD2,EIF4EBP1,ELOC,FAS,GATA6,HK2,ITPR1,LONP1,MYC,NAMPT,NOP53,PLK3,PMAIP1,PRKAA1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS27A,STC2,TBL2,TLR2,TMBIM6,UBA52,UBQLN1 |
| GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER | 0.0e+00 | 1.0e-07 | 1603 | 188 | 25 | CCNC,CDK4,CDK8,DHX36,ESRRG,GTF2B,GTF2E2,MED26,MED8,MNAT1,NR1D1,NR1D2,NR1H2,POLR2C,POLR2H,POLR2J,PPM1D,PSMC5,SGF29,TAF1,TAF4,TAF4B,TAF6,TBP,ZNF451 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | 0.0e+00 | 1.0e-07 | 1603 | 110 | 19 | GPC6,MKS1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SAPCD2,SMURF2 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 1.0e-07 | 1603 | 1716 | 102 | ABCC4,ADAMTS1,AGO3,AIMP1,ANXA1,AREG,ATF3,BTG3,CASK,CCL5,CD320,CDC123,CDK4,CFDP1,CIAO1,CIB1,CNBP,CNOT7,CRKL,CSNK2A1,DDX20,DICER1,E2F7,EIF2AK2,EIF5A2,EMD,EPGN,EREG,ETV5,EZH2,FGF8,FLT1,FOSL1,GATA6,GNAI3,GNL3,GTPBP4,HBEGF,HDAC4,HES1,HMGA1,HOXA3,IER5,IL23A,IL4R,ING1,KARS1,KLF10,MAP2K1,MKS1,MNAT1,MORC3,MSX1,MYC,NAMPT,NIBAN2,NME2,NOLC1,NOP2,NPM1,NR1D1,ODC1,OSGIN1,PDCD2,PDCD5,PDGFA,PID1,PIM1,PIM2,PNP,PPM1D,PRDX4,PRKAA1,PRMT1,PRNP,PTBP2,RPL23,RPS15A,RPS3,RPS4X,RPS6KB1,RPS9,SAPCD2,SELENOK,SERPINB5,SGK3,SHMT2,SMPD3,SPHK1,SPRY2,TBX20,TFAP4,TFRC,TGFA,TIPIN,TLR2,TNC,VAX1,WDR77,XRCC6,ZFP36,ZNF609 |
| GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS | 0.0e+00 | 1.0e-07 | 1603 | 148 | 22 | ABT1,AGO3,BOP1,CNOT1,CNOT7,DICER1,EDC3,EXOSC1,MRPL44,NOB1,NOCT,NOP14,PDE12,PIWIL1,PIWIL2,RPP30,RPP40,RPS21,SLFN13,TSN,UTP23,XRN2 |
| GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 1.0e-07 | 1603 | 328 | 34 | BCL10,CAB39,CERS1,CRY1,DHX36,EEF1D,EIF2S1,FAS,FNTB,GADD45A,GCLC,HAMP,HDAC4,HUS1,MYC,N4BP1,NAMPT,NET1,NEUROD2,NMT1,NPM1,PPID,RAC1,RAD9A,RHNO1,RP1,RPL26,RUVBL2,TAF1,TENT2,TMEM161A,WRN,XRCC6,YBX3 |
| GO_MRNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 1.0e-07 | 1603 | 111 | 19 | AAAS,DDX19B,DDX39A,ENY2,MAGOH,NUP54,NUP58,NUP88,NUP93,NUP98,SEC13,SRSF1,SRSF3,SRSF7,THOC6,U2AF1,U2AF2,UPF1,WDR33 |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 1.0e-07 | 1603 | 1428 | 89 | ADAMTS9,ADM2,AMIGO2,ANKRD27,ANKRD54,ANXA1,AURKA,CDH4,CIB1,CPNE5,CRKL,CTH,DHX36,DICER1,DLX2,DOCK5,ETV5,EVI2B,EZH2,FBXO38,FGF8,FLT1,FOXA2,FOXC2,GATA6,GDF15,GOLGA4,HAMP,HAX1,HES1,HK2,HMGA1,HSP90AB1,IL23A,IL4R,KAT2A,KATNB1,KLF10,MAP2K1,MAPK9,MARK2,MOB2,MORF4L2,MTDH,MYC,NBL1,NEUROD2,NIBAN2,NME2,NOCT,PAFAH1B1,PAK4,PDCD2,PDGFA,PIM1,PLD6,PLK2,PNP,PRDM14,PRKAA1,PRMT1,PRMT5,RAC1,RACK1,RBM19,RFX3,RHEB,RHEX,RPS6KB1,RUNX1,SEMA3A,SERP1,SETD3,SHLD3,SLC9B2,SLIT2,SMAD5,SMURF2,SPHK1,SS18L1,SUCO,TBX20,TFRC,TLR2,UBE2V2,WDFY2,YBX3,ZFP36,ZNF609 |
| GO_ORGANELLE_FISSION | 0.0e+00 | 1.0e-07 | 1603 | 450 | 41 | AAAS,ANAPC5,AURKA,BCCIP,BOD1,BORA,CCDC36,CCSAP,CDC23,CDC26,CEP85,CEP97,CHTF8,COX10,EPGN,EREG,FBXO43,FGF8,GPR3,KATNB1,MEIOC,MSTO1,MSX1,MTFP1,MTFR1,NAA50,PDXP,PIWIL2,PRMT5,PSMD13,PSRC1,RAD51B,RIOK2,RPL24,SHCBP1L,SMPD3,TERB2,TEX14,TGFA,ZNF207,ZW10 |
| GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1603 | 177 | 24 | ANAPC5,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,GNL3,KAT2A,MAP3K4,MAPKAPK5,NBN,PHF19,PIH1D1,PIWIL2,PNKP,POT1,PPHLN1,RUVBL2,SHCBP1L,SMARCB1,TCP1 |
| GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 0.0e+00 | 1.0e-07 | 1603 | 544 | 46 | AREG,ARL13B,BCL10,BRSK1,CARMIL2,CD44,CEP290,EPHA2,ETV5,FGF8,FOXC2,FOXF2,FOXQ1,GPC6,HBEGF,HES1,KAT2A,LIAS,MKS1,MTHFD1L,MYC,PAFAH1B1,PDGFA,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SAPCD2,SEMA3A,SERPINB5,SLIT2,SMURF2,SPRY2,TBX20,TNC |
| GO_CELLULAR_RESPONSE_TO_DRUG | 0.0e+00 | 1.0e-07 | 1603 | 436 | 40 | AIM2,ANXA1,ATG7,CBX3,CDK4,CERS1,CRKL,EIF4EBP1,EZH2,GCLC,GCLM,GNAI3,HRH1,HSP90AB1,HTR7,KLF16,MSX1,MT2A,MTR,MYC,NET1,PDXP,PRKAA1,PRMT5,PRNP,PYCR1,RACK1,RAP1B,RGS4,RPS3,RPS6KB1,SLC31A1,SLIT2,SMPD3,TAF1,TFAP4,TFRC,TMEM38B,TRAP1,TXN |
| GO_RNA_METHYLATION | 0.0e+00 | 1.0e-07 | 1603 | 79 | 16 | BUD23,DIMT1,EMG1,METTL1,METTL16,METTL2A,MTO1,NOP2,NSUN4,NSUN5,RNMT,TFB1M,TFB2M,THUMPD3,TRMO,TRMT61A |
| GO_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS | 0.0e+00 | 1.0e-07 | 1603 | 41 | 12 | DFFA,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,PAM16,RFFL,RPS3 |
| GO_GOLGI_VESICLE_TRANSPORT | 0.0e+00 | 1.0e-07 | 1603 | 367 | 36 | AP1AR,AREG,ARF4,ARFGAP3,ARFRP1,ARL1,CNST,COG1,COPB1,COPB2,COPE,DYNC1LI2,GAK,GOLGA4,GOLPH3L,GOSR2,KDELR2,LMAN1,MCFD2,MYO1B,NBAS,RACK1,RINT1,SEC13,SEC23A,SEC24A,SEC24D,SYS1,TBC1D14,TFG,TGFA,TMED1,TMED9,TRAPPC2B,TRAPPC6B,ZW10 |
| GO_RESPONSE_TO_UV | 0.0e+00 | 1.0e-07 | 1603 | 139 | 21 | BRSK1,CERS1,DHX36,EIF2S1,HUS1,MAP3K4,MYC,N4BP1,NPM1,PPID,PRIMPOL,PRKAA1,RHNO1,RPL26,RUVBL2,TAF1,TIPIN,TMEM161A,TYR,WRN,ZRANB3 |
| GO_CELL_ACTIVATION | 0.0e+00 | 1.0e-07 | 1603 | 1442 | 89 | ADGRG3,ADORA2B,AKAP17A,ANXA1,APOLD1,ATAD3B,ATG7,ATP11B,BATF3,BCL10,BTLA,CAB39,CANT1,CCL5,CCT2,CCT8,CD14,CD320,CD44,CEBPG,CEP290,CFP,CMTM7,COPB1,COTL1,CRACR2A,DDOST,DGKG,DNAJB9,EEF1A1,ERP44,GCLC,GCLM,GON4L,HDAC4,HES1,HSP90AA1,HSP90AB1,IL23A,IL4R,ILF2,ITPR1,KARS1,KAT2A,LILRA5,LYL1,MFHAS1,NAMPT,NBN,NME2,NR1D1,PDGFA,PGAM1,PNP,PPIE,PRDX4,PRMT5,PRNP,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAC1,RAP1B,RPS3,RPS6,RUNX1,SELENOK,SHLD3,SNAP25,SNX27,SPHK1,TBC1D10C,TBK1,TFRC,TLR2,TMEM106A,TMEM98,TXNDC5,UBASH3B,WBP2NL,XRCC6,ZC3H8 |
| GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 1.0e-07 | 1603 | 286 | 31 | CEP85,CERS1,CIB1,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,FOXA2,GADD45A,IPO5,NPM1,PAQR3,POT1,PPP2CA,PRKAR1B,RACK1,RGS4,RPL11,RPL23,RPL5,RTRAF,SPRED1,SPRED2,SPRY2,SPRY4,TFAP4,TRIB2,TRIB3,UBASH3B,ZFP36 |
| GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | 0.0e+00 | 1.0e-07 | 1603 | 141 | 21 | ARIH2,DDIT3,DNLZ,HAX1,HK2,HSP90AA1,HSPA4,LMAN1,NMT1,PAM16,PDCD5,PITRM1,PMAIP1,PRKAA1,SLC25A6,TIMM13,TIMM23B,TIMM9,TOMM20,TOMM34,YWHAE |
| GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1603 | 81 | 16 | OAZ1,ODC1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1 |
| GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 0.0e+00 | 1.0e-07 | 1603 | 116 | 19 | DHX36,EIF2AK2,GATA6,HES1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RUNX1 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1603 | 259 | 29 | ATG7,CSNK2A1,DFFA,DHX36,HSP90AB1,LARS1,LRPPRC,MCL1,MEIOC,METTL16,N4BP1,NAMPT,NBAS,NOCT,NOP53,PAM16,PSMF1,QSOX1,RPL11,RPL23,RPL5,TAF1,TARDBP,TBC1D14,TENT2,TENT4B,YBX1,YBX3,ZFP36 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1603 | 143 | 21 | ARIH1,ARIH2,AURKA,CSNK1A1,FBXL5,GCLC,HERPUD1,HSP90AA1,MAPK9,NOP53,PLK2,PLK3,RACK1,RAD23A,RNF19A,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_RESPONSE_TO_TOXIC_SUBSTANCE | 0.0e+00 | 2.0e-07 | 1603 | 539 | 45 | ABCG2,ANXA1,AREG,ARHGAP33,ASNS,BLMH,CCL5,CD14,CDK4,CERS1,DUOX2,EIF4EBP1,EZH2,FOSL1,GLRX2,HAMP,KCNK1,MSX1,MT2A,NET1,PIM1,PON3,PRDX4,PRKAA1,PSMD14,PYCR1,RACK1,RGS17,RGS4,RPL10A,RPL15,RPS3,RPS6KB1,SELENOS,SESN2,SLC31A1,SMPD3,SRXN1,TLR2,TNC,TRAP1,TUFM,TXN,UBA52,UBIAD1 |
| GO_SNRNA_TRANSCRIPTION | 0.0e+00 | 2.0e-07 | 1603 | 72 | 15 | GTF2B,GTF2E2,INTS10,INTS13,INTS4,INTS6,POLR2C,POLR2H,POLR2J,SNAPC1,SNAPC2,TAF6,TBP,ZC3H8,ZNF143 |
| GO_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | 0.0e+00 | 2.0e-07 | 1603 | 83 | 16 | EIF2AK2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RUNX1 |
| GO_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 0.0e+00 | 2.0e-07 | 1603 | 62 | 14 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,DHX36,MAP3K4,MAPKAPK5,PNKP,POT1,TCP1,TENT4B |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 0.0e+00 | 2.0e-07 | 1603 | 119 | 19 | BYSL,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,IPO5,MFHAS1,NMD3,NOLC1,NPM1,NUP54,NUP58,SESN2,TARDBP,TCP1,TMEM98 |
| GO_RESPONSE_TO_LIGHT_STIMULUS | 0.0e+00 | 2.0e-07 | 1603 | 311 | 32 | ASNS,BRSK1,CACNA1F,CCDC66,CERS1,CRY1,DHX36,EIF2S1,FNTB,HRH1,HUS1,MAP3K4,MYC,N4BP1,NETO1,NMT1,NPM1,PPID,PRIMPOL,PRKAA1,RHNO1,RP1,RPL26,RUVBL2,SLC1A2,TAF1,TENT2,TIPIN,TMEM161A,TYR,WRN,ZRANB3 |
| GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1603 | 95 | 17 | FBXL5,FBXO38,FBXO48,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1 |
| GO_REGULATION_OF_NUCLEAR_DIVISION | 0.0e+00 | 2.0e-07 | 1603 | 187 | 24 | ANAPC5,AURKA,BORA,CCDC36,CCSAP,CDC23,CDC26,CEP85,CEP97,EPGN,EREG,FBXO43,FGF8,GPR3,MSX1,PDXP,PIWIL2,PRMT5,RIOK2,SMPD3,TEX14,TGFA,ZNF207,ZW10 |
| GO_VIRAL_LIFE_CYCLE | 0.0e+00 | 2.0e-07 | 1603 | 328 | 33 | AAAS,AEN,APOBEC3A,APOBEC3D,ATG16L1,BANF1,CCL5,CNOT7,EIF2AK2,EPHA2,HSP90AB1,IDE,NECTIN1,NUP54,NUP58,NUP88,NUP93,NUP98,PDCD6IP,PDE12,PPID,PPIE,RAD23A,RPS27A,RPSA,SEC13,SLC1A5,SMARCB1,TFRC,TRIM11,UBA52,VTA1,XPO1 |
| GO_PEPTIDYL_LYSINE_MODIFICATION | 0.0e+00 | 2.0e-07 | 1603 | 397 | 37 | AAAS,BRPF1,CTH,CXXC1,DOHH,EEF1AKMT4,EZH2,GFI1,GNL3,GTF2B,HDAC4,JADE3,KAT2A,KAT8,LIAS,MORF4L2,MRGBP,NAA50,NUP54,NUP58,NUP88,NUP93,NUP98,PHF19,PHF20,PIH1D1,PIWIL2,POLE4,PRKAA1,RUVBL2,SETD3,SGF29,SMARCB1,SUMO1,TAF1,VCPKMT,ZNF451 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 2.0e-07 | 1603 | 232 | 27 | BCL10,CRY1,DERL1,FOXF2,GCLC,GNL3,GTPBP4,HDAC4,HERPUD1,HSP90AA1,HSP90AB1,MAPK9,N4BP1,NOP53,NPM1,RPL11,RPL23,RPL5,RPS2,RPS3,SIAH2,SPHK1,SVBP,TAF1,TRIB3,U2AF2,UBQLN1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 2.0e-07 | 1603 | 526 | 44 | ABI2,AIM2,AMIGO2,AP1AR,ARPC5L,BAIAP2L2,BUD23,CARMIL2,CDC34,CLDN19,CNOT1,DIMT1,EPHA2,G3BP1,G3BP2,HDAC4,HSP90AA1,IDE,LDB2,MAPK9,MAPRE1,NAV3,NR1H2,PDCD6IP,PFN2,PIH1D1,PLEK2,PMAIP1,PSMC5,PSRC1,RAB3GAP2,RAC1,RACK1,RAP1B,RIOK1,RIOK2,RP1,RPS3,SMPD3,SUMO1,UBE2V2,UTP15,WDR43,ZMYND10 |
| GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | 0.0e+00 | 2.0e-07 | 1603 | 133 | 20 | AURKA,CD44,CNOT1,CNOT7,E2F7,GADD45A,MSX1,NBN,NPM1,PLK2,PLK3,PMAIP1,PPM1D,PRMT1,RINT1,RPL26,SESN2,SPRED1,SPRED2,TFAP4 |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 2.0e-07 | 1603 | 1335 | 83 | AAAS,ABI2,ANXA1,AP1AR,ARHGAP18,ARPC5L,AURKA,BAIAP2L2,BCCIP,BICD1,BIN3,BORA,BRSK1,C10orf90,C9orf72,CARMIL2,CCDC66,CCSAP,CEP85,CEP97,CFAP74,CIB1,CLDN19,COTL1,CSNK1A1,DYNC1LI2,EPB41,FMNL2,GADD45A,HAX1,INTS13,KAT2A,KATNA1,KATNB1,KATNBL1,MAPRE1,MARK2,MARK3,MOB2,MSTO1,MYO1B,NAV3,NPM1,NUBP1,PAFAH1B1,PAK4,PDCD6IP,PDGFA,PDXP,PFDN2,PFN2,PLEK2,PLK2,PLK3,PPFIA1,PRKAA1,PSRC1,RAC1,RAP1GDS1,RGS4,RNF19A,RP1,RPS3,RTTN,SAPCD2,SDAD1,SETD3,SLC16A1,SLIT2,SPAG1,SPRY2,STRIP2,SYNE3,TMOD3,TPM3,TRIM36,TUBD1,TUBE1,UXT,XPO1,ZMYND10,ZNF207,ZW10 |
| GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1603 | 314 | 32 | ATG7,BSCL2,CSNK2A1,DFFA,DHX36,HDAC4,HSP90AB1,LARS1,LRPPRC,MCL1,MEIOC,METTL16,N4BP1,NAMPT,NBAS,NOCT,NOP53,PAM16,PRKAA1,PSMF1,QSOX1,RPL11,RPL23,RPL5,TAF1,TARDBP,TBC1D14,TENT2,TENT4B,YBX1,YBX3,ZFP36 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1603 | 219 | 26 | ARIH1,ARIH2,ATG7,AURKA,CSNK1A1,CSNK2A1,FBXL5,GCLC,HERPUD1,HSP90AA1,IDE,MAPK9,NOP53,OAZ1,PLK2,PLK3,RACK1,RAD23A,RNF19A,SMURF2,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 3.0e-07 | 1603 | 250 | 28 | ETV5,FGF8,FOXC2,GPC6,HES1,MKS1,MSX1,MYC,PDGFA,PIM1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SAPCD2,SMURF2,TNFRSF11B |
| GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | 0.0e+00 | 3.0e-07 | 1603 | 299 | 31 | ADAMTS1,ANXA1,AURKA,BCAT1,CDC34,CDK4,CNOT1,CNOT7,E2F6,E2F7,ECD,EIF4EBP1,EZH2,GADD45A,GFI1,MAX,MNAT1,MYC,ORC3,ORC4,PIM2,PLK2,PLK3,PLRG1,POLE4,PRIM2,PRMT1,RPL26,RPS6,RPS6KB1,TAF1 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS_INVOLVED_IN_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1603 | 122 | 19 | ARIH1,ARIH2,AURKA,CSNK1A1,GCLC,HERPUD1,MAPK9,NOP53,PLK2,PLK3,RACK1,RAD23A,RNF19A,SUMO1,TAF1,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION | 0.0e+00 | 3.0e-07 | 1603 | 29 | 10 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,GNL3,POT1,TCP1 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 3.0e-07 | 1603 | 532 | 44 | AAAS,BPGM,COQ10B,COX10,COX4I1,DLST,ECD,EIF6,FDX2,GFPT1,GFPT2,GLRX2,GNPDA1,HAAO,HDAC4,HK2,IDE,IREB2,MTCO2P12,MTFR1,MYC,NDUFA5,NDUFAF2,NDUFB11,NOP53,NR1D1,NUP54,NUP58,NUP88,NUP93,NUP98,PDE12,PFKP,PGAM1,PHGDH,PHKG1,PID1,PRKAA1,SEC13,SELENOS,SHMT2,SLC25A14,STK40,TRAP1 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 0.0e+00 | 4.0e-07 | 1603 | 76 | 15 | PDIA3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1 |
| GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 0.0e+00 | 4.0e-07 | 1603 | 710 | 53 | ADGRG3,ADORA2B,ANXA1,ATAD3B,ATG7,ATP11B,CAB39,CANT1,CCT2,CCT8,CD14,CD44,CEP290,CFP,COPB1,COTL1,CRACR2A,DDOST,EEF1A1,ERP44,HSP90AA1,HSP90AB1,IL23A,IL4R,ILF2,KARS1,NBN,NME2,PGAM1,PNP,PPIE,PRDX4,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAC1,RAP1B,RPS6,SHLD3,SNAP25,TBC1D10C,TFRC,TLR2,TMEM98,TXNDC5,XRCC6 |
| GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 4.0e-07 | 1603 | 287 | 30 | ASF1A,CENPN,GTF2B,H2BC11,H2BC12,H2BC13,H2BC8,H3C14,H4C2,H4C3,H4C4,HMGA1,MNAT1,MYC,NPM1,ORC3,PIH1D1,PIWIL1,POLR1E,PSMC5,PSME4,RAD23B,RPL23,RPS27A,SGF29,SMARCB1,TAF1,TAF6,TBP,UBA52 |
| GO_AMINE_METABOLIC_PROCESS | 0.0e+00 | 4.0e-07 | 1603 | 138 | 20 | AADAT,CHDH,HAAO,OAZ1,ODC1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,SMS |
| GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | 0.0e+00 | 5.0e-07 | 1603 | 181 | 23 | ANXA1,EIF6,ERFE,NR1D1,NR1H2,OAZ1,ODC1,PRKAB2,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,TRIB3 |
| GO_PROTEIN_N_LINKED_GLYCOSYLATION | 0.0e+00 | 5.0e-07 | 1603 | 78 | 15 | ALG10B,ALG14,DDOST,DPM1,DPM2,GFPT1,GFPT2,LMAN1,MCFD2,NUS1,PGM3,PMM2,RPN1,SYVN1,TMEM258 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 1603 | 620 | 48 | AAAS,ABHD10,ATF3,B4GALT3,BPGM,CREM,CRY1,DUSP12,ECD,EIF6,ERFE,FOXA2,FUT2,FUT9,GCLC,GLO1,GNPDA1,GNPDA2,HDAC4,HK2,HRH1,IMPA1,IMPAD1,KAT2A,NANS,NLN,NR1D1,NUP54,NUP58,NUP88,NUP93,NUP98,PFKP,PGAM1,PGM3,PHKG1,PMAIP1,PMM2,PRKAA1,SEC13,SELENOS,SERP1,SESN2,SLC35A2,SMPD3,ST3GAL4,STK40,UEVLD |
| GO_CYTOPLASMIC_TRANSLATIONAL_INITIATION | 0.0e+00 | 6.0e-07 | 1603 | 31 | 10 | EIF2S2,EIF2S3,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M,EIF4EBP1,RPL13A |
| GO_NIK_NF_KAPPAB_SIGNALING | 0.0e+00 | 6.0e-07 | 1603 | 183 | 23 | ADGRG3,AGO3,CD14,DICER1,EIF2AK2,IL23A,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS3,SPHK1,TLR2 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 6.0e-07 | 1603 | 1187 | 75 | ADORA2B,AIM2,ANKRD54,ANXA1,BCL10,BTLA,CACNA1F,CCL20,CCL5,CD14,CD320,CFP,CREB3,CRKL,DDX21,DHX36,DMBT1,EIF2B2,EREG,EVI2B,FBXO38,GFI1,HAX1,HES1,HSP90AA1,HSP90AB1,ICAM3,IL23A,IL4R,IRAK2,KARS1,KLF10,MAPKAPK3,MASP2,MFHAS1,NOP53,NR1D1,OTULIN,PDCD2,PDE4D,PNP,POLR3D,PRMT1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RHEX,RPS19,RPS27A,RPS3,RUNX1,SELENOK,SHLD3,SLC9B2,TBK1,TFRC,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_REGULATION_OF_TRANSLATIONAL_INITIATION | 0.0e+00 | 6.0e-07 | 1603 | 79 | 15 | C8orf88,CCL5,CDC123,EIF1,EIF1B,EIF2AK2,EIF2B2,EIF2S1,EIF3K,EIF4EBP1,EIF4H,NPM1,PAIP2,RPL13A,RPS6KB1 |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 7.0e-07 | 1603 | 723 | 53 | ABCB11,ACOT7,ADK,ALDH18A1,ALDH8A1,ANXA1,ASNS,ATF3,BCAT1,BHMT2,CNBP,COQ10B,COQ6,CRY1,CTH,DSE,EIF6,ERFE,GFI1,GPT2,HAAO,HRH1,IMPA1,IMPAD1,KAT2A,LIAS,MTHFD1L,MTR,MTRR,NFYA,NLN,NME2,NR1D1,NR1H2,NT5C,NUDT1,NUS1,PDE4D,PGAM1,PHGDH,PNP,PRKAA1,PRKAB2,PSAT1,PYCR1,SELENOS,SESN2,SHMT2,SMPD3,SPHK1,SPTLC2,TRIB3,UBIAD1 |
| GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 0.0e+00 | 8.0e-07 | 1603 | 436 | 38 | ACRBP,ARL1,ATL1,BAIAP2L2,BANF1,BIN3,CCDC47,COG1,CSNK1A1,DYM,EMD,GAK,GET4,GOLGA8A,GOLGA8B,GOLPH3L,LMAN1,MAP2K1,NUP93,PAFAH1B1,PDCD6IP,PLK3,PPP2CA,PPP2R2A,PRMT5,RAB27A,RAB2A,RAB3GAP2,RFX2,SEC61A1,SERP1,TARDBP,TMED1,TMED9,TMEM38B,UBL4A,VTA1,ZW10 |
| GO_MITOTIC_NUCLEAR_DIVISION | 0.0e+00 | 8.0e-07 | 1603 | 264 | 28 | AAAS,ANAPC5,AURKA,BCCIP,BOD1,BORA,CCSAP,CDC23,CDC26,CEP85,CEP97,CHTF8,EPGN,EREG,FGF8,KATNB1,MSTO1,NAA50,PDXP,PRMT5,PSRC1,RIOK2,RPL24,SMPD3,TEX14,TGFA,ZNF207,ZW10 |
| GO_MYELOID_CELL_DIFFERENTIATION | 0.0e+00 | 9.0e-07 | 1603 | 420 | 37 | AGO3,ANKRD54,BATF3,BPGM,CEBPG,CIB1,EIF6,EPHA2,EVI2B,GLO1,H3C14,H4C2,H4C3,H4C4,HAX1,IL23A,IREB2,KAT8,KLF10,MFHAS1,MYC,NME2,PABPC4,PAFAH1B1,PRMT1,RHEX,RPS14,RPS19,RPS6,RUNX1,SLC9B2,SMAD5,TFRC,TLR2,TMOD3,UBASH3B,ZFP36 |
| GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 9.0e-07 | 1603 | 514 | 42 | ADORA2B,AIM2,BCL10,CCL5,CD14,DMBT1,EREG,GFI1,ICAM3,IL23A,IRAK2,KARS1,LILRA5,MAPKAPK3,MFHAS1,NOP53,NR1D1,OTULIN,POLR3D,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS19,RPS27A,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_RRNA_METHYLATION | 0.0e+00 | 1.0e-06 | 1603 | 25 | 9 | BUD23,DIMT1,EMG1,METTL16,NOP2,NSUN4,NSUN5,TFB1M,TFB2M |
| GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 0.0e+00 | 1.0e-06 | 1603 | 334 | 32 | ADORA2B,BORA,CAB39,CCL5,CRKL,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,GADD45A,GDF15,IL23A,IRAK2,KARS1,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MARK2,PAK4,PRKAA1,PRKAR1B,PRNP,PRR5,PRRC1,RPLP1,RPS27A,TGFA,TXN,UBA52 |
| GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 1.1e-06 | 1603 | 204 | 24 | AAAS,CRY1,DUSP12,ECD,EIF6,ERFE,FOXA2,HDAC4,HRH1,KAT2A,NLN,NR1D1,NUP54,NUP58,NUP88,NUP93,NUP98,PGAM1,PMAIP1,PRKAA1,SEC13,SELENOS,SESN2,SMPD3 |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 1.1e-06 | 1603 | 1116 | 71 | ABCE1,ADORA2B,AIM2,ANXA1,BCL10,BTLA,CACNA1F,CCL5,CD14,CD8B2,CDC37,CFP,CNOT7,CRKL,DDX21,DHX36,DMBT1,EIF2B2,EREG,FBXO38,GFI1,HSP90AA1,HSP90AB1,ICAM3,IFNGR2,IL23A,IL4R,IRAK2,KARS1,MAPK9,MAPKAPK3,MASP2,MFHAS1,NCR3LG1,NOP53,NR1D1,NR1H2,OTULIN,PDE4D,POLR3D,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RPS19,RPS27A,RPS3,RUNX1,SELENOS,SHLD3,SUMO1,TBK1,TFRC,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 1.0e-07 | 1.1e-06 | 1603 | 335 | 32 | ADORA2B,ASNS,ATF3,ATG7,BCL10,EIF2AK2,EIF2S1,FAS,FOSL1,FOXA2,GADD45A,GCLC,GLRX2,HDAC4,KLF10,LARS1,MARS1,MAX,NAMPT,NUDT1,PDXP,PIM1,PMAIP1,PPM1D,PRKAA1,RAC1,SESN2,SLC1A2,TAF1,TBL2,TNC,WRN |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | 1.0e-07 | 1.2e-06 | 1603 | 190 | 23 | AP1S2,CANX,DYNC1LI2,IDE,PDIA3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,SEC13,SEC23A,SEC24A,SEC24D |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 1.0e-07 | 1.2e-06 | 1603 | 371 | 34 | AMER3,CSNK1A1,CSNK1G3,CSNK2A1,DDIT3,EMD,G3BP1,GRB10,HMGXB4,MDFI,MKS1,NLE1,OTULIN,PPP2CA,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RUNX1,RUVBL2,SIAH2,SMURF2,TLR2 |
| GO_CELL_CYCLE_ARREST | 1.0e-07 | 1.2e-06 | 1603 | 237 | 26 | AURKA,CAB39,CDC123,CDK4,CNOT1,CNOT7,DDIT3,E2F7,EVI2B,GADD45A,GADD45GIP1,GATA6,HSP90AB1,MAP2K1,MYC,NBN,PLK2,PLK3,PRKAA1,PRKAB2,PRMT1,PRNP,RHEB,RPL23,RPL26,TFAP4 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 1.0e-07 | 1.2e-06 | 1603 | 337 | 32 | ADORA2B,CAB39,CIB1,CRKL,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EZH2,FLT1,GADD45A,GDF15,HSP90AB1,IRAK2,KARS1,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MNAT1,PDGFA,PIH1D1,PPP2CA,PRKAA1,PSRC1,RPS27A,RPS3,SPRY2,TGFA,UBA52 |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1.0e-07 | 1.2e-06 | 1603 | 463 | 39 | AAAS,AADAT,ABCG2,ACBD6,ACOT7,ACOT9,ADK,ADORA2B,AK2,BPGM,CASK,DLST,ECD,EFL1,EIF6,EPHA2,FAR1,GNAI3,GTPBP1,HDAC4,HK2,IMPAD1,MTCO2P12,MTHFD1L,NME2,NT5C,NUDT1,NUP54,NUP58,NUP88,NUP93,NUP98,PDE4D,PFKP,PGAM1,PID1,PNP,PRKAA1,SEC13 |
| GO_VESICLE_TARGETING | 1.0e-07 | 1.2e-06 | 1603 | 95 | 16 | AP1AR,AREG,ARFGAP3,C17orf75,GOSR2,LMAN1,MCFD2,SEC13,SEC23A,SEC24A,SEC24D,STARD3NL,TFG,TGFA,TMED9,TRAPPC6B |
| GO_ENDOPLASMIC_RETICULUM_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT | 1.0e-07 | 1.4e-06 | 1603 | 207 | 24 | AREG,ARF4,ARFGAP3,COG1,COPB1,COPB2,COPE,DYNC1LI2,GOSR2,KDELR2,LMAN1,MCFD2,RINT1,SEC13,SEC23A,SEC24A,SEC24D,TFG,TGFA,TMED1,TMED9,TRAPPC2B,TRAPPC6B,ZW10 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 1.0e-07 | 1.5e-06 | 1603 | 804 | 56 | ABCE1,ADORA2B,AIM2,ANXA1,BCL10,C5orf30,CCL5,CD14,CDC37,CNOT7,DMBT1,EREG,GFI1,HSP90AB1,ICAM3,IFNGR2,IL23A,IRAK2,KARS1,LILRA5,MAPKAPK3,MFHAS1,NOP53,NR1D1,NR1D2,NR1H2,OTULIN,POLR3D,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS19,RPS27A,SELENOK,SELENOS,SPATA2,SPHK1,SUMO1,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 1.5e-06 | 1603 | 289 | 29 | AEN,CD44,CHAC1,CREB3,DDIT3,EDA2R,EPHA2,HERPUD1,ITPR1,MCL1,MSX1,NBN,PMAIP1,RACK1,RAD9A,RPL11,RPL26,RPS3,SELENOK,SELENOS,SYVN1,TMBIM6,TMEM161A,TPT1,TRAP1,TRIB3,UBQLN1,URI1,YBX3 |
| GO_POSITIVE_REGULATION_OF_RIBOSOME_BIOGENESIS | 1.0e-07 | 1.7e-06 | 1603 | 9 | 6 | BUD23,DIMT1,RIOK1,RIOK2,UTP15,WDR43 |
| GO_MITOTIC_CELL_CYCLE_CHECKPOINT | 1.0e-07 | 1.8e-06 | 1603 | 165 | 21 | AURKA,BRSK1,CNOT1,CNOT7,E2F7,GADD45A,HUS1,NBN,NOP53,PLK2,PLK3,PRMT1,RAD9A,RINT1,RPL24,RPL26,RPS6,TEX14,TIPIN,ZNF207,ZW10 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 1.0e-07 | 1.9e-06 | 1603 | 895 | 60 | ADORA2B,AIM2,ANXA1,BCL10,CACNA1F,CCL5,CD14,CFP,CRKL,DDX21,DHX36,DMBT1,EIF2B2,EREG,FBXO38,GFI1,HSP90AA1,HSP90AB1,ICAM3,IL23A,IL4R,IRAK2,KARS1,MAPKAPK3,MASP2,MFHAS1,NOP53,NR1D1,OTULIN,PDE4D,POLR3D,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RPS19,RPS27A,RPS3,RUNX1,SHLD3,TBK1,TFRC,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1.0e-07 | 1.9e-06 | 1603 | 587 | 45 | ATF3,BOD1,C9orf72,CEP85,CIB1,CNST,CRKL,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,FOXA2,GADD45A,HDAC4,IPO5,MFHAS1,MYC,NPM1,PAFAH1B1,PAQR3,PDE12,PDE4D,PDGFA,PID1,PPP1R14B,PPP2CA,PRKAR1B,PRNP,RACK1,RGS4,RTRAF,SLIT2,SPRED1,SPRED2,SPRY2,SPRY4,TARDBP,TBC1D10C,TFAP4,TRIB2,TRIB3,UBASH3B,URI1,YWHAE |
| GO_INACTIVATION_OF_MAPK_ACTIVITY | 1.0e-07 | 2.0e-06 | 1603 | 27 | 9 | DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,PPP2CA,RGS4,SPRED1,SPRED2 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 1.0e-07 | 2.0e-06 | 1603 | 362 | 33 | AIM2,ARIH1,ARIH2,AURKA,BCL10,BLID,CLPX,CSNK1A1,FAS,GCLC,HERPUD1,KARS1,MAPK9,MYC,NOP53,PDCD2,PDCD5,PLK2,PLK3,PMAIP1,PSMD14,PSME4,RACK1,RAD23A,RNF19A,RPS3,SUMO1,TAF1,TFAP4,TRIB2,TRIB3,UBE2V2,UBQLN1 |
| GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 2.0e-06 | 1603 | 166 | 21 | CD44,CREB3,DDIT3,HERPUD1,MCL1,MSX1,PMAIP1,RACK1,RAD9A,RPL11,RPL26,RPS3,SELENOS,SYVN1,TMBIM6,TMEM161A,TPT1,TRAP1,UBQLN1,URI1,YBX3 |
| GO_RRNA_MODIFICATION | 1.0e-07 | 2.0e-06 | 1603 | 35 | 10 | BUD23,DIMT1,EMG1,METTL16,NOP10,NOP2,NSUN4,NSUN5,TFB1M,TFB2M |
| GO_VESICLE_TARGETING_TO_FROM_OR_WITHIN_GOLGI | 1.0e-07 | 2.1e-06 | 1603 | 75 | 14 | AP1AR,AREG,ARFGAP3,GOSR2,LMAN1,MCFD2,SEC13,SEC23A,SEC24A,SEC24D,TFG,TGFA,TMED9,TRAPPC6B |
| GO_DEFENSE_RESPONSE_TO_VIRUS | 1.0e-07 | 2.1e-06 | 1603 | 244 | 26 | ABCC9,ABCE1,AEN,AIM2,AIMP1,APOBEC3A,APOBEC3D,ATG7,CNOT7,DDX21,DHX36,DMBT1,EIF2AK2,G3BP1,GBP3,IL23A,NOP53,PDE12,PMAIP1,POLR3D,SELENOK,SLFN13,TBK1,TRAF3,TRIM11,TTC4 |
| GO_EPITHELIUM_DEVELOPMENT | 1.0e-07 | 2.2e-06 | 1603 | 1296 | 78 | ABI2,ANXA1,ANXA7,APOLD1,AREG,ARL13B,BCCIP,BCL10,BRSK1,CARMIL2,CD44,CEP290,DMBT1,E2F7,EPHA2,EREG,ETV5,EZH2,FGF8,FOXC2,FOXF2,FOXQ1,GATA6,GPC6,HBEGF,HES1,KAT2A,LDB2,LIAS,MAFF,MAP2K1,MARVELD2,MKS1,MSX1,MTHFD1L,MYC,NLE1,NME2,PAFAH1B1,PDE4D,PDGFA,PELO,PHGDH,PIH1D1,PPHLN1,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RAP1B,RFX3,RHEB,RILPL1,RUNX1,SAPCD2,SEMA3A,SERPINB5,SLIT2,SMAD5,SMURF2,SPRY2,TBX20,TMEM38B,TNC,WDR77,ZFP36 |
| GO_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 1.0e-07 | 2.2e-06 | 1603 | 261 | 27 | AIM2,BCL10,BUD31,CEBPG,CIB1,COPS5,CTH,DDIT3,EDA2R,EIF2AK2,FOSL1,HDAC4,IRAK2,MTDH,NEUROD2,NPM1,PSMA6,RHEBL1,RPS27A,RPS3,RWDD1,SMARCB1,SPHK1,TAF1,TLR2,UBA52,ZIC2 |
| GO_PROTEIN_COMPLEX_OLIGOMERIZATION | 1.0e-07 | 2.2e-06 | 1603 | 493 | 40 | AIM2,ATG16L1,ATL1,BCL10,CAB39,CTH,CUTC,DDIT3,DYNC1LI2,EPPIN,FARSB,G3BP2,H4C2,H4C3,H4C4,HACL1,IDE,KCNG1,KCNG4,KCTD3,KCTD5,KCTD6,LONP1,NME2,NUP54,NUP58,PANX1,PDCD6IP,PFKP,PMAIP1,PRKAA1,PRMT1,PRNP,RACK1,RPS19,SHMT2,SLC1A2,SLC1A5,THG1L,YME1L1 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 1.0e-07 | 2.5e-06 | 1603 | 534 | 42 | ABI2,AP1AR,ARHGAP18,ARPC5L,AURKA,BAIAP2L2,BICD1,BORA,C10orf90,C9orf72,CARMIL2,CCSAP,CEP85,CEP97,CIB1,COTL1,HAX1,KAT2A,KATNB1,KATNBL1,MAPRE1,MARK2,NAV3,NPM1,NUBP1,PAFAH1B1,PDCD6IP,PDGFA,PDXP,PFDN2,PFN2,PLK2,PPFIA1,PRKAA1,PSRC1,RAC1,RGS4,RPS3,SLIT2,TMOD3,TRIM36,XPO1 |
| GO_RESPONSE_TO_HEAT | 1.0e-07 | 2.4e-06 | 1603 | 183 | 22 | AAAS,CD14,CLPB,DHX36,EIF2B2,EIF2S1,GCLC,HSP90AA1,HSP90AB1,HSP90AB3P,HSPA13,IER5,NUP54,NUP58,NUP88,NUP93,NUP98,RPS6KB1,SEC13,STAC,SUMO1,YWHAE |
| GO_COFACTOR_BIOSYNTHETIC_PROCESS | 1.0e-07 | 2.5e-06 | 1603 | 230 | 25 | ACOT7,BOLA2B,CHAC1,CIAO1,COQ10B,COQ6,COX10,DUOX2,GCLC,GCLM,HAAO,IREB2,LIAS,METTL16,MMADHC,MMS19,MTCO2P12,MTHFD1L,NADK,NAMPT,NUBP1,NUBP2,PSAT1,SRRD,UBIAD1 |
| GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY | 1.0e-07 | 2.6e-06 | 1603 | 36 | 10 | CCT2,CCT4,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,MYC,PNKP,POT1,TCP1 |
| GO_REGULATION_OF_GENE_SILENCING | 1.0e-07 | 2.5e-06 | 1603 | 154 | 20 | AAAS,ASF1A,H3C14,H4C2,H4C3,H4C4,HMGA1,MAP2K1,NUP54,NUP58,NUP88,NUP93,NUP98,POLR2C,POLR2H,POLR2J,PPHLN1,SEC13,XPO5,ZFP36 |
| GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 1.0e-07 | 2.7e-06 | 1603 | 264 | 27 | ADORA2B,ASNS,ATF3,ATG7,EIF2AK2,EIF2S1,FAS,FOSL1,FOXA2,GLRX2,KLF10,LARS1,MARS1,MAX,NAMPT,NUDT1,PDXP,PIM1,PMAIP1,PPM1D,PRKAA1,SESN2,SLC1A2,TAF1,TBL2,TNC,WRN |
| GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 2.7e-06 | 1603 | 231 | 25 | CD44,CREB3,CSNK2A1,CTH,FAS,GCLC,GCLM,GNAI3,HERPUD1,MCL1,NLE1,PAM16,PIH1D1,RFFL,RPS6KB1,SELENOS,SGK3,SIAH2,SYVN1,TMBIM6,TMEM161A,TPT1,TRAP1,URI1,YBX3 |
| GO_PROTEIN_TARGETING_TO_MITOCHONDRION | 1.0e-07 | 2.8e-06 | 1603 | 101 | 16 | ARIH2,DNLZ,HAX1,HSP90AA1,HSPA4,LMAN1,PAM16,PDCD5,PITRM1,PRKAA1,SLC25A6,TIMM13,TIMM23B,TIMM9,TOMM20,TOMM34 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 2.0e-07 | 2.9e-06 | 1603 | 351 | 32 | ANXA1,ATG7,CAB39,DDIT3,EIF2S1,ETV5,EZH2,FAS,GLRX2,LONP1,MAPK9,MCL1,MTR,NET1,NME2,PRKAA1,PYCR1,RACK1,RBM11,RPS3,RWDD1,SELENOS,SESN2,SMPD3,SRXN1,TMEM161A,TRAP1,TXN,UBQLN1,VRK2,XRCC6,YBX3 |
| GO_GAMETE_GENERATION | 2.0e-07 | 2.9e-06 | 1603 | 698 | 50 | ACRBP,ADAMTS1,AURKA,CCDC36,CDK16,CIB1,CREM,CRKL,DDX20,DHX36,EIF2S2,EIF5A2,EREG,ETV5,FAM9C,FOSL1,HERC4,IL4R,MEIOC,OR7C1,PAFAH1B1,PAIP2,PAQR5,PGM3,PHC2,PIWIL1,PIWIL2,PLD6,PRDM14,PRDX4,PSME4,RAD23B,RFX2,RNF114,RNF2,RPS6,RPS6KB1,SFMBT1,SHCBP1L,SMAD5,SPATA2,SPATA5,SPIN2A,TAF4B,TBP,TEX14,USP42,WDR33,XRN2,YBX3 |
| GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 2.0e-07 | 2.9e-06 | 1603 | 216 | 24 | CSNK1A1,DDIT3,EMD,G3BP1,GRB10,HMGXB4,MDFI,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RACK1,RUVBL2,SIAH2 |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 2.0e-07 | 2.9e-06 | 1603 | 499 | 40 | ANXA7,ATG16L1,ATG7,C9orf72,CDC37,CSNK2A1,DDIT3,EEF1A1,EVA1A,GNAI3,HAX1,HK2,HSP90AA1,ITPR1,KAT8,LARS1,MARK2,MCL1,MTDH,NAMPT,PIM2,PLK2,PLK3,PRKAA1,PRKAB2,QSOX1,RAB24,RAB3GAP2,RHEB,RMC1,SESN2,SPTLC2,TBC1D14,TBK1,TMBIM6,TMEM208,TOMM20,TRIB3,UBQLN1,VTA1 |
| GO_TRANSCRIPTION_BY_RNA_POLYMERASE_I | 2.0e-07 | 2.9e-06 | 1603 | 66 | 13 | MARS1,MNAT1,NOP53,PIH1D1,POLR1E,POLR2H,SMARCB1,TAF1,TAF1A,TAF1D,TBP,UTP15,WDR43 |
| GO_RESPONSE_TO_TEMPERATURE_STIMULUS | 2.0e-07 | 3.0e-06 | 1603 | 249 | 26 | AAAS,CD14,CLPB,DHX36,EIF2B2,EIF2S1,GCLC,GLRX2,HSP90AA1,HSP90AB1,HSP90AB3P,HSPA13,IER5,MTCO2P12,NUP54,NUP58,NUP88,NUP93,NUP98,PRKAA1,RPS6KB1,SEC13,STAC,SUMO1,YBX3,YWHAE |
| GO_CELL_CELL_SIGNALING_BY_WNT | 2.0e-07 | 3.3e-06 | 1603 | 521 | 41 | AGO3,AMER3,CSNK1A1,CSNK1G3,CSNK2A1,DDIT3,EMD,G3BP1,GPC6,GRB10,HMGXB4,MARK2,MDFI,MKS1,NLE1,OTULIN,PPP2CA,PRKAA1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RACK1,RPS27A,RUNX1,RUVBL2,SIAH2,SMURF2,TLR2,UBA52 |
| GO_REGULATION_OF_GROWTH | 2.0e-07 | 3.2e-06 | 1603 | 680 | 49 | ARMC10,CDH4,CDK11B,CDK4,CIB1,CPNE5,CRKL,CSNK2A1,DUSP6,FGF8,FOXC2,FSTL4,GATA6,GDF15,GOLGA4,HAMP,HBEGF,ING1,KCTD6,MORF4L2,MRGBP,MSX1,MT2A,NET1,NPM1,NUBP1,OSGIN1,OSGIN2,PAFAH1B1,PAK4,PIM1,PPP2CA,PSRC1,RACK1,RGS4,RPS6KB1,RUVBL2,SEMA3A,SERP1,SESN2,SGK3,SLIT2,SOCS7,SPHK1,STC2,TBX20,URI1,WRN,YBX3 |
| GO_DNA_REPLICATION | 2.0e-07 | 3.4e-06 | 1603 | 267 | 27 | ATG7,CDC34,CHTF8,E2F7,EREG,GTPBP4,HMGA1,HUS1,LIG3,NBN,ORC3,ORC4,PNKP,POLD2,POLE4,PPP2CA,PRIM2,PRIMPOL,RAC1,RAD9A,RHNO1,RMI2,TIPIN,TOP1MT,UPF1,WRN,ZRANB3 |
| GO_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING | 2.0e-07 | 3.5e-06 | 1603 | 116 | 17 | AAAS,H3C14,H4C2,H4C3,H4C4,MAP2K1,NUP54,NUP58,NUP88,NUP93,NUP98,POLR2C,POLR2H,POLR2J,SEC13,XPO5,ZFP36 |
| GO_MITOCHONDRIAL_RNA_METABOLIC_PROCESS | 2.0e-07 | 4.0e-06 | 1603 | 47 | 11 | AARS1,EARS2,GARS1,LRPPRC,MTO1,PDE12,POLRMT,PRKAA1,TFB2M,TRIT1,TRNT1 |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 2.0e-07 | 4.0e-06 | 1603 | 960 | 62 | ABCC4,ADAMTS1,ANXA1,AREG,ATF3,CCL5,CD320,CDC123,CDK4,CIAO1,CIB1,CNBP,CNOT7,CRKL,CSNK2A1,EIF5A2,EPGN,EREG,ETV5,EZH2,FGF8,FLT1,FOSL1,GATA6,GNAI3,HBEGF,HDAC4,HES1,HOXA3,IL23A,MNAT1,MYC,NAMPT,NME2,NOLC1,NOP2,NPM1,ODC1,PDCD2,PDGFA,PID1,PIM1,PNP,PRKAA1,PRMT1,RPL23,RPS15A,RPS3,RPS4X,RPS6KB1,RPS9,SAPCD2,SELENOK,SHMT2,SMPD3,SPHK1,TBX20,TFRC,TGFA,TIPIN,TNC,WDR77 |
| GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 2.0e-07 | 3.9e-06 | 1603 | 220 | 24 | AURKA,BICD1,BORA,C10orf90,CCSAP,CEP85,CEP97,CIB1,KAT2A,KATNB1,MAPRE1,MARK2,NAV3,NPM1,NUBP1,PAFAH1B1,PDCD6IP,PLK2,PRKAA1,PSRC1,RAC1,RPS3,TRIM36,XPO1 |
| GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 2.0e-07 | 4.0e-06 | 1603 | 189 | 22 | ABCE1,CCL5,CDC37,CNOT7,GFI1,H2BC11,HSP90AB1,IFNGR2,IRAK2,NR1H2,OTULIN,PAFAH1B1,RACK1,RFFL,RUNX1,SLIT2,SPATA2,SPHK1,SUMO1,TBK1,TLR2,VRK2 |
| GO_DNA_CONFORMATION_CHANGE | 2.0e-07 | 4.3e-06 | 1603 | 322 | 30 | ANXA1,ASF1A,BANF1,CENPN,CHTF8,DHX36,G3BP1,H2BC11,H2BC12,H2BC13,H2BC8,H3C14,H4C2,H4C3,H4C4,HMGA1,MNAT1,NBN,NPM1,PIWIL1,POT1,PSME4,RAD23B,RPS27A,RUVBL2,TOP1MT,UBA52,WRN,XRCC6,ZRANB3 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 2.0e-07 | 4.3e-06 | 1603 | 469 | 38 | ATF3,C9orf72,CEP85,CIB1,CRKL,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,FOXA2,GADD45A,HDAC4,IPO5,MYC,NPM1,PAFAH1B1,PAQR3,PDE12,PDE4D,PID1,PPP2CA,PRKAR1B,PRNP,RACK1,RGS4,RTRAF,SLIT2,SPRED1,SPRED2,SPRY2,SPRY4,TARDBP,TBC1D10C,TFAP4,TRIB2,TRIB3,UBASH3B |
| GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 2.0e-07 | 4.3e-06 | 1603 | 586 | 44 | AAAS,AGO3,ASF1A,CNOT1,CNOT7,DDX21,DICER1,EIF6,EZH2,H3C14,H4C2,H4C3,H4C4,HDAC4,HMGA1,KAT2A,MAP2K1,MBD1,MORF4L2,MRPL44,NUP54,NUP58,NUP88,NUP93,NUP98,PCGF6,PHF19,POLR1E,POLR2C,POLR2H,POLR2J,PPHLN1,PPM1D,PRDM14,SEC13,SPOUT1,TAF1A,TAF1D,TBP,TFAP2C,TSN,UPF1,XPO5,ZFP36 |
| GO_EMBRYO_DEVELOPMENT | 2.0e-07 | 4.4e-06 | 1603 | 1029 | 65 | APBA1,ARFRP1,ARL13B,BCL10,BTF3,BYSL,C2orf49,CCSAP,CEP290,DHX36,DLX2,E2F7,EIF2S2,EMG1,EN2,EPHA2,FGF8,FLT1,FOSL1,FOXA2,FOXC2,FOXF2,GATA6,HES1,HOXA3,HUS1,IMPAD1,KAT2A,LIAS,MAFF,MAP2K1,MDFI,MKS1,MSX1,MTHFD1L,NBN,NIBAN2,NLE1,NMT1,NOCT,NOLC1,PAFAH1B1,PDGFA,PELO,PHGDH,PLD6,PRDM14,RACK1,RAD23B,RBM19,RNF2,RPL10,RPL38,RPS6,RRP7A,RTCB,SEC24D,SEMA3A,SF3B6,SIM2,SMAD5,SPRY2,TBX20,YBX1,YBX3 |
| GO_TOR_SIGNALING | 2.0e-07 | 4.5e-06 | 1603 | 118 | 17 | C9orf72,EIF4EBP1,GPAT3,LARS1,MAPKAPK5,PIH1D1,PIP4P1,PRKAA1,PRR5,RFFL,RHEB,RHEBL1,RPS6,RPS6KB1,SEC13,SESN2,UBR1 |
| GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 2.0e-07 | 4.6e-06 | 1603 | 548 | 42 | ADORA2B,CCL20,CCL5,CD44,CIB1,CRKL,DNAJC27,DUSP5,DUSP6,DUSP7,EDA2R,EIF2AK2,EPGN,EZH2,FGF8,FLT1,GADD45A,GDF15,IRAK2,KARS1,KLHDC10,LILRA5,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,MFHAS1,PDGFA,PELI2,PRKAA1,PRMT1,RAP1B,RELL1,RPS27A,RPS3,SEMA3A,SPHK1,SPRY2,TGFA,TMEM106A,UBA52 |
| GO_REGULATION_OF_TELOMERASE_ACTIVITY | 3.0e-07 | 5.0e-06 | 1603 | 48 | 11 | CCT2,CCT4,CERS1,HSP90AA1,HSP90AB1,MAP3K4,MAPKAPK5,MYC,PNKP,POT1,TCP1 |
| GO_GOLGI_VESICLE_BUDDING | 3.0e-07 | 5.2e-06 | 1603 | 81 | 14 | AREG,ARFGAP3,GOLPH3L,GOSR2,LMAN1,MCFD2,SEC13,SEC23A,SEC24A,SEC24D,TFG,TGFA,TMED9,TRAPPC6B |
| GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | 3.0e-07 | 5.2e-06 | 1603 | 106 | 16 | AURKA,BRSK1,CNOT1,CNOT7,E2F7,GADD45A,HUS1,NBN,NOP53,PLK2,PLK3,PRMT1,RAD9A,RINT1,RPL26,TIPIN |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 3.0e-07 | 5.3e-06 | 1603 | 1124 | 69 | ABCE1,ADORA2B,AIM2,ANXA1,ANXA5,BCL10,C5orf30,CASK,CCL5,CD14,CDC37,CNOT7,CREB3,DMBT1,EREG,FNTB,FOXA2,GFI1,HSP90AB1,ICAM3,IFNGR2,IL23A,IRAK2,KARS1,LILRA5,MAP2K1,MAPKAPK3,MFHAS1,NBL1,NMT1,NOP53,NR1D1,NR1D2,NR1H2,OTULIN,PDGFA,POLR3D,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RPS19,RPS27A,SELENOK,SELENOS,SEMA3A,SLIT2,SPATA2,SPHK1,SUMO1,TBK1,TLR2,TRAF3,UBA52,UBASH3B,UBE2D2,UBQLN1,XRCC6 |
| GO_FORMATION_OF_CYTOPLASMIC_TRANSLATION_INITIATION_COMPLEX | 3.0e-07 | 5.5e-06 | 1603 | 16 | 7 | EIF2S2,EIF3C,EIF3D,EIF3I,EIF3J,EIF3K,EIF3M |
| GO_PROTEIN_KINASE_B_SIGNALING | 3.0e-07 | 5.4e-06 | 1603 | 274 | 27 | AREG,CCL5,CIB1,DDIT3,EPGN,EPHA2,EREG,FGF8,GDF15,HAX1,HBEGF,HSP90AA1,HSP90AB1,MFHAS1,MTDH,NOP53,PDGFA,PLK3,RAC1,RACK1,RPS6KB1,SESN2,SMPD3,SPRY2,TGFA,TRIB3,TXN |
| GO_UDP_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS | 3.0e-07 | 5.5e-06 | 1603 | 16 | 7 | GFPT1,GFPT2,GNPDA1,GNPDA2,PGM3,SLC35A3,UAP1 |
| GO_NUCLEOTIDE_SUGAR_BIOSYNTHETIC_PROCESS | 4.0e-07 | 6.3e-06 | 1603 | 23 | 8 | GFPT1,GFPT2,GNPDA1,GNPDA2,NANS,PGM3,PMM2,UAP1 |
| GO_VESICLE_LOCALIZATION | 4.0e-07 | 6.2e-06 | 1603 | 210 | 23 | AP1AR,AP3M2,AP3S2,AREG,ARFGAP3,BRSK1,C17orf75,GOSR2,LMAN1,MCFD2,MREG,PAFAH1B1,RAB27A,RAB27B,SEC13,SEC23A,SEC24A,SEC24D,STARD3NL,TFG,TGFA,TMED9,TRAPPC6B |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION | 4.0e-07 | 6.7e-06 | 1603 | 227 | 24 | AP1S2,CANX,DYNC1LI2,IDE,PDIA3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAB27A,SEC13,SEC23A,SEC24A,SEC24D |
| GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY | 4.0e-07 | 6.8e-06 | 1603 | 150 | 19 | AGO3,GPC6,MKS1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SMURF2 |
| GO_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | 4.0e-07 | 7.6e-06 | 1603 | 181 | 21 | ETV5,GPC6,MKS1,PDGFA,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SAPCD2,SMURF2 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 4.0e-07 | 7.6e-06 | 1603 | 1318 | 77 | ADAMTS9,ADORA2B,ANXA1,ANXA5,AREG,C5orf30,CIB1,CRY1,DDIT3,DICER1,DLX2,DOCK5,EPHA2,FGF8,FOXA2,FOXC2,FSTL4,GAK,GATA6,GDF15,GFI1,H4C2,H4C3,H4C4,HAMP,HDAC4,HES1,HOMER2,HSP90AB1,IL23A,IL4R,LILRA5,MYC,NAV3,NEUROD2,NIBAN2,NME2,NOCT,NR1D1,NR1H2,PAFAH1B1,PAQR3,PDE4D,PDGFA,PFN2,PLK2,PPP2CA,PRDX4,PRMT1,PRNP,RAC1,RFX8,RGS4,RHEB,RPS19,RUNX1,SARS1,SELENOS,SEMA3A,SFMBT1,SLIT2,SPRED1,SPRY2,STC2,SVBP,TBK1,TLR2,TMEM98,TNFRSF11B,TRIB2,TRIM11,UBASH3B,VAX1,WDR77,YBX3,ZC3H8,ZFP36 |
| GO_UDP_N_ACETYLGLUCOSAMINE_BIOSYNTHETIC_PROCESS | 4.0e-07 | 7.7e-06 | 1603 | 11 | 6 | GFPT1,GFPT2,GNPDA1,GNPDA2,PGM3,UAP1 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 4.0e-07 | 8.0e-06 | 1603 | 724 | 50 | ANKRD27,AP1AR,ASF1A,CARMIL2,CEP97,CIB1,DFFA,EIF4EBP1,FBXO43,FSTL4,GAK,GCLC,GFI1,HMGA1,KAT2A,KATNB1,LMAN1,MAPRE1,MNAT1,NAV3,NBN,NEUROD2,NOP53,NPM1,NR1H2,NUBP1,PAFAH1B1,PAM16,PAQR3,PFN2,PIH1D1,PLK2,POT1,PPFIA1,PRNP,RAC1,RPL13A,SACS,SEMA3A,SLIT2,SMARCB1,SPRY2,TBX20,TENT4B,TEX14,TLR2,TMOD3,ZNF207,ZNF451,ZW10 |
| GO_PEPTIDE_SECRETION | 4.0e-07 | 8.0e-06 | 1603 | 641 | 46 | AIM2,AIMP1,ANXA1,ANXA5,ARFGAP3,CANX,CCL5,CD14,CDK16,DHX36,DPH3,ENY2,FOXA2,GOLPH3L,IL4R,ITPR1,KARS1,LILRA5,M6PR,MON1A,NADK,NDUFAF2,NR1D1,NR1H2,PAFAH1B1,PANX1,PNP,PPID,RAC1,RFX3,SEC24A,SEL1L,SELENOK,SERP1,SLC16A1,SLC25A6,SLC9B2,SMPD3,SNAP25,SVBP,TARDBP,TLR2,TMBIM6,TMEM106A,TMEM167A,TVP23B |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 4.0e-07 | 8.0e-06 | 1603 | 297 | 28 | ADAMTS1,ANAPC5,ANXA1,AURKA,CDK4,CNOT1,CNOT7,E2F7,EPGN,EREG,EZH2,FGF8,GADD45A,GATA6,MSX1,NPM1,PIWIL2,PLK2,PLK3,PLRG1,PRMT1,RAD51B,RHNO1,RPL23,RPL26,SMPD3,TGFA,TMOD3 |
| GO_POSITIVE_REGULATION_OF_BINDING | 5.0e-07 | 8.2e-06 | 1603 | 182 | 21 | CEBPG,DERL1,DPH3,EIF2S1,EIF3C,EIF3D,EPB41,GTF2B,HES1,HOXA3,HSP90AB1,MAPRE1,MARK3,NIBAN2,NMD3,PLK2,PPP2CA,RPL11,TAF1,TRIB3,TXN |
| GO_CELLULAR_HOMEOSTASIS | 5.0e-07 | 8.9e-06 | 1603 | 963 | 61 | ABCG2,ANXA5,ANXA7,CCDC47,CCL5,CDK16,DDIT3,DMXL1,ENY2,ERFE,ERP44,FBXL5,FOXA2,GCLC,GCLM,GLRX2,HAAO,HAMP,HERPUD1,HK2,IDE,IMMT,IREB2,ITPR1,MCL1,MICU2,MT2A,MYC,NADK,NDUFAF2,NME2,NPM1,NR1D1,NUBP1,PDE4D,PDIA3,PDIA6,PIH1D1,PRDX4,PRKAA1,PRNP,QSOX1,RAC1,RACK1,RAP1GDS1,SELENOK,SELENOS,SLC31A1,SLC39A6,SLC39A7,SLC9B2,SMARCB1,STC2,TFRC,TMBIM6,TMEM38B,TPT1,TXN,TXNDC5,UBASH3B,YWHAE |
| GO_NUCLEOTIDE_EXCISION_REPAIR | 5.0e-07 | 9.4e-06 | 1603 | 111 | 16 | COPS5,HUS1,LIG3,MMS19,MNAT1,PNKP,POLD2,POLR2C,POLR2H,POLR2J,PPIE,RAD23A,RAD23B,RPS27A,TCEA1,UBA52 |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 6.0e-07 | 9.7e-06 | 1603 | 372 | 32 | AADAT,ACBD6,ACOT7,ACOT9,AHCYL1,B4GALT3,BHMT2,BLMH,BOLA2B,CHAC1,CIAO1,CTH,DLST,DSE,FAR1,GCLC,GCLM,GLO1,GLRX2,GSTM5,IMPAD1,LIAS,METTL16,MMS19,MTR,MTRR,NUBP1,NUBP2,PHGDH,SLC35D2,SMS,ST3GAL4 |
| GO_PEPTIDYL_SERINE_MODIFICATION | 6.0e-07 | 1.1e-05 | 1603 | 319 | 29 | AURKA,BCAR3,CAB39,CD44,CSNK1A1,CSNK1G3,CSNK2A1,HAX1,HSP90AA1,HSP90AB1,MAPK9,MAPKAPK3,MAPKAPK5,MARK2,MARK3,MORC3,PAQR3,PDE4D,PFN2,PLK2,PRKAA1,RACK1,RPS6KB1,SGK3,SPRY2,TAF1,TBK1,TXN,VRK2 |
| GO_CELL_CYCLE_CHECKPOINT | 6.0e-07 | 1.1e-05 | 1603 | 217 | 23 | AURKA,BRSK1,CNOT1,CNOT7,CRY1,E2F7,GADD45A,HUS1,NBN,NOP53,PLK2,PLK3,PRMT1,RAD9A,RHNO1,RINT1,RPL24,RPL26,RPS6,TEX14,TIPIN,ZNF207,ZW10 |
| GO_TISSUE_MORPHOGENESIS | 6.0e-07 | 1.1e-05 | 1603 | 670 | 47 | AREG,ARL13B,BCL10,BRSK1,CARMIL2,CD44,CEP290,EPHA2,ETV5,FGF8,FOXC2,FOXF2,FOXQ1,GPC6,HBEGF,HES1,KAT2A,LIAS,MKS1,MSX1,MTHFD1L,MYC,PAFAH1B1,PDGFA,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,SAPCD2,SEMA3A,SERPINB5,SLIT2,SMURF2,SPRY2,TBX20,TNC |
| GO_NEGATIVE_REGULATION_OF_RNA_CATABOLIC_PROCESS | 7.0e-07 | 1.2e-05 | 1603 | 63 | 12 | DHX36,LRPPRC,MEIOC,METTL16,NBAS,NOCT,TARDBP,TENT2,TENT4B,YBX1,YBX3,ZFP36 |
| GO_RIBOSOMAL_SMALL_SUBUNIT_EXPORT_FROM_NUCLEUS | 7.0e-07 | 1.2e-05 | 1603 | 7 | 5 | NPM1,NUP88,RIOK2,RPS15,XPO1 |
| GO_CELLULAR_RESPONSE_TO_LIGHT_STIMULUS | 7.0e-07 | 1.2e-05 | 1603 | 127 | 17 | CERS1,CRY1,DHX36,EIF2S1,FNTB,MYC,N4BP1,NMT1,NPM1,PPID,RHNO1,RP1,RPL26,RUVBL2,TAF1,TENT2,TMEM161A |
| GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 7.0e-07 | 1.2e-05 | 1603 | 75 | 13 | CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,IPO5,NMD3,NPM1,SESN2,TARDBP,TCP1 |
| GO_CELLULAR_RESPONSE_TO_HEAT | 8.0e-07 | 1.3e-05 | 1603 | 142 | 18 | AAAS,CLPB,DHX36,EIF2S1,HSP90AA1,HSP90AB1,HSP90AB3P,HSPA13,IER5,NUP54,NUP58,NUP88,NUP93,NUP98,SEC13,STAC,SUMO1,YWHAE |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 8.0e-07 | 1.3e-05 | 1603 | 737 | 50 | ANXA1,ANXA5,ARHGEF1,ATF3,ATG7,BCL10,BLID,CCL5,CDC34,CDK4,CTNNBL1,DDIT3,DDX20,DFFA,DUSP6,EIF2S1,FAS,FOSL1,GADD45A,HDAC4,KATNB1,MAPK9,MCL1,MSX1,MTCO2P12,MYC,NET1,NMT1,OSGIN1,PDCD2,PDCD5,PDIA3,PHLDA1,PMAIP1,PPID,PRNP,PTRH2,RACK1,RAD9A,RPL11,RPL26,RPS27A,RPS3,RPS6,SAP18,SLIT2,TFAP4,UBA52,YWHAE,ZC3H8 |
| GO_COVALENT_CHROMATIN_MODIFICATION | 8.0e-07 | 1.3e-05 | 1603 | 473 | 37 | AURKA,BRPF1,COPRS,CXXC1,ELK4,ENY2,EZH2,GFI1,GTF2B,HDAC4,JADE3,KAT2A,KAT8,MBD1,MIER2,MORF4L2,MRGBP,NAA50,PCGF6,PHF19,PHF20,PIH1D1,PIWIL2,POLE4,PPHLN1,PRDM14,PRKAA1,PRMT1,PRMT5,RNF2,RUVBL2,SETD3,SGF29,SMARCB1,TAF1,USP15,ZNF451 |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 8.0e-07 | 1.4e-05 | 1603 | 1000 | 62 | ADAMTS9,ANKRD27,ANKRD54,ANXA1,AURKA,CDH4,CIB1,CPNE5,CRKL,CTH,DHX36,DICER1,DLX2,DOCK5,ETV5,EVI2B,EZH2,FBXO38,FGF8,GATA6,GDF15,GOLGA4,HAMP,HAX1,HES1,HSP90AB1,IL23A,IL4R,KAT2A,KATNB1,KLF10,MAP2K1,MAPK9,MARK2,MOB2,MORF4L2,NBL1,NEUROD2,NIBAN2,NME2,NOCT,PAFAH1B1,PNP,PRMT1,PRMT5,RAC1,RFX3,RHEB,RHEX,RUNX1,SEMA3A,SETD3,SLC9B2,SLIT2,SMAD5,SS18L1,SUCO,TLR2,UBE2V2,WDFY2,ZFP36,ZNF609 |
| GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 9.0e-07 | 1.5e-05 | 1603 | 115 | 16 | BCL10,ICAM3,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1 |
| GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 1.0e-06 | 1.6e-05 | 1603 | 363 | 31 | ATG7,COPS5,DCAF13,ELOC,EVA1A,FBXL5,FBXO10,FEM1C,FN3KRP,KCTD6,KLHL2,PDIA6,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,QSOX1,RAB2A,STC2,TNC,UCHL3 |
| GO_OXIDATION_REDUCTION_PROCESS | 1.0e-06 | 1.7e-05 | 1603 | 1005 | 62 | ABCC4,ALDH18A1,ALDH8A1,BPGM,CHDH,COQ10B,COQ6,COX10,COX4I1,CYP2C19,DLST,DOHH,DUOX2,DUS4L,FAR1,FDX2,GFPT1,GFPT2,GLRX2,HAAO,HACL1,HCCS,HK2,HSD17B14,IDE,IL4I1,IREB2,KDSR,MTCO2P12,MTFR1,MTHFD1L,MTHFD2,MTRR,MYC,NDUFA5,NDUFAF2,NDUFB11,NOP53,NR1D1,PDIA3,PDIA6,PFKP,PGAM1,PHGDH,PHKG1,PID1,PRDX4,PRKAA1,PYCR1,QSOX1,SELENOS,SESN2,SHMT2,SLC25A14,SRXN1,STK40,TRAP1,TXN,TYR,TYW1B,TYW5,UEVLD |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 1.1e-06 | 1.8e-05 | 1603 | 704 | 48 | AHCYL1,ANXA1,ANXA5,ASNS,CBX3,CDK4,CNOT1,CRKL,CRY1,DDX18,EIF4EBP1,EPRS1,ERFE,ESRRG,FHL2,FOSB,FOXC2,GATA6,GCLC,GCLM,GDF15,GRB10,HDAC4,IDE,KCTD6,MARS1,MAX,NR1D1,NR1D2,NR1H2,PID1,PRKAA1,PRKAR1B,RAP1B,RPS6KB1,RUNX1,RUVBL2,RWDD1,SELENOS,SLIT2,TFAP4,TNC,TRIB3,UBA5,UFM1,UFSP2,URI1,ZFP36 |
| GO_DNA_DEPENDENT_DNA_REPLICATION | 1.1e-06 | 1.9e-05 | 1603 | 146 | 18 | ATG7,CDC34,CHTF8,E2F7,HMGA1,LIG3,NBN,ORC3,ORC4,PNKP,POLD2,POLE4,PRIM2,PRIMPOL,TIPIN,UPF1,WRN,ZRANB3 |
| GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 1.1e-06 | 1.9e-05 | 1603 | 258 | 25 | CEP85,CIB1,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,FOXA2,GADD45A,IPO5,NPM1,PAQR3,PPP2CA,PRKAR1B,RACK1,RGS4,RTRAF,SPRED1,SPRED2,SPRY2,SPRY4,TFAP4,TRIB2,TRIB3,UBASH3B |
| GO_PROTEIN_IMPORT | 1.1e-06 | 1.9e-05 | 1603 | 192 | 21 | DNLZ,HSP90AA1,HSPA4,IPO5,NOLC1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,PAM16,PDCD5,RGPD5,RPL23,SNUPN,SPRN,TARDBP,TIMM23B,TNPO3,TOMM20 |
| GO_REGULATION_OF_AUTOPHAGY | 1.1e-06 | 1.8e-05 | 1603 | 328 | 29 | ATG7,C9orf72,CDC37,DDIT3,EEF1A1,GNAI3,HAX1,HK2,ITPR1,KAT8,LARS1,MCL1,MTDH,NAMPT,PIM2,PLK2,PLK3,PRKAA1,PRKAB2,QSOX1,RAB3GAP2,RHEB,RMC1,SESN2,SPTLC2,TBC1D14,TBK1,TRIB3,UBQLN1 |
| GO_REGULATION_OF_PROTEIN_BINDING | 1.1e-06 | 1.8e-05 | 1603 | 224 | 23 | AURKA,DERL1,EIF2S1,EPB41,HDAC4,HOXA3,HSP90AB1,MAP2K1,MAPRE1,MARK2,MARK3,MITD1,NMD3,PIM2,PLK2,PPP2CA,RPL11,RUVBL2,TAF1,TEX14,TMBIM6,TRIB3,UBASH3B |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 1.2e-06 | 2.0e-05 | 1603 | 643 | 45 | ADORA2B,AIM2,BCL10,CCL5,CD14,CREB3,DMBT1,EREG,GFI1,ICAM3,IL23A,IRAK2,KARS1,LILRA5,MAPKAPK3,MFHAS1,NOP53,NR1D1,OTULIN,POLR3D,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RPS19,RPS27A,SLIT2,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 1.2e-06 | 2.0e-05 | 1603 | 348 | 30 | AAAS,ADORA2B,ARIH2,CEP290,CIB1,DNAJC27,EIPR1,EMD,HAX1,IL4R,IPO5,LMAN1,MAP2K1,NOLC1,NUP54,NUP58,NUS1,OAZ1,PDCD5,PLK3,PRKAA1,PRNP,RINT1,RIOK2,TARDBP,TXN,XPO1,XPO5,YWHAE,ZFAND1 |
| GO_STRESS_GRANULE_ASSEMBLY | 1.2e-06 | 2.1e-05 | 1603 | 19 | 7 | BICD1,C9orf72,EIF2S1,G3BP1,G3BP2,PRKAA1,RPS23 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 1.3e-06 | 2.2e-05 | 1603 | 709 | 48 | AHCYL1,ANXA5,ATG7,CDK4,CRKL,EIF4EBP1,EPRS1,ERFE,EZH2,FOXC2,GCLC,GCLM,GDF15,GNAI3,GRB10,HRH1,HTR7,IDE,IPO5,KLF10,KLF16,LARS1,MARS1,MAX,MTR,NAMPT,NPM1,PDE12,PDE4D,PDXP,PID1,PRKAA1,PRKAR1B,PRMT5,PRNP,RAP1B,RGS4,RPL23,RPS6KB1,SELENOS,SESN2,SHMT2,SLIT2,SMPD3,TAF1,TMEM38B,TRIB3,UBR1 |
| GO_ION_TRANSPORT | 1.4e-06 | 2.3e-05 | 1603 | 1692 | 91 | ABCB11,ABCC4,ABCC9,ABCG2,AHCYL1,ALG10B,ANXA1,ANXA5,APBA1,ATP11B,CA5B,CAB39,CACNA1F,CASK,CBARP,CCL5,CNNM4,COX10,COX4I1,CRACR2A,CUTC,DDIT3,EPB41,EPPIN,EPRS1,ERFE,GABRA2,HAMP,HOMER2,IREB2,ITPR1,KCNG1,KCNG4,KCNK1,KCNQ5,LILRA5,MFSD2A,MICU2,MTCO2P12,NECTIN1,NETO1,NIPAL4,PANX1,PDE4D,PKD2L2,PPFIA1,PRELID3B,PRKAB2,PRNP,PROCA1,RGS4,RHBG,RHD,RPS6KB1,SEC61A1,SELENOK,SGK3,SLC10A5,SLC16A1,SLC16A6,SLC1A2,SLC1A5,SLC25A14,SLC25A6,SLC31A1,SLC35A2,SLC35A3,SLC35D2,SLC36A4,SLC39A6,SLC39A7,SLC6A15,SLC7A1,SLC7A5,SLC7A9,SLC9B2,SLCO4A1,SLCO5A1,SNAP25,STAC,STC2,SUMO1,TFRC,TMBIM6,TMC2,TMEM38B,TPT1,UBASH3B,UBQLN1,YME1L1,YWHAE |
| GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 1.4e-06 | 2.3e-05 | 1603 | 227 | 23 | ARIH2,CEP290,CIB1,DNAJC27,EMD,HAX1,IPO5,LMAN1,NOLC1,NUP54,NUP58,OAZ1,PDCD5,PLK3,PRKAA1,PRNP,RIOK2,TARDBP,TXN,XPO1,XPO5,YWHAE,ZFAND1 |
| GO_RESPONSE_TO_HORMONE | 1.4e-06 | 2.3e-05 | 1603 | 994 | 61 | AHCYL1,ANXA1,ANXA5,AREG,ASNS,CBX3,CDK4,CNOT1,CRKL,CRY1,DDX18,EIF2B2,EIF4EBP1,EIF6,EPRS1,EREG,ERFE,ESRRG,EZH2,FHL2,FOSB,FOSL1,FOXC2,GATA6,GCLC,GCLM,GDF15,GRB10,HDAC4,IDE,KCTD6,LONP1,MARS1,MAX,MMS19,NME2,NR1D1,NR1D2,NR1H2,PID1,PRKAA1,PRKAR1B,RAP1B,RPS6KB1,RUNX1,RUVBL2,RWDD1,SELENOS,SESN2,SLIT2,STC2,TFAP4,TLR2,TNC,TOMM20,TRIB3,UBA5,UFM1,UFSP2,URI1,ZFP36 |
| GO_AMINO_SUGAR_BIOSYNTHETIC_PROCESS | 1.5e-06 | 2.5e-05 | 1603 | 13 | 6 | GFPT1,GFPT2,GNPDA1,GNPDA2,PGM3,UAP1 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 1.5e-06 | 2.4e-05 | 1603 | 228 | 23 | AGO3,C8orf88,CNOT1,CNOT7,DHX36,EIF2AK2,EIF2S1,EIF4EBP1,EIF6,EPRS1,IGF2BP3,IREB2,METTL16,PAIP2,PRKAA1,PRNP,RACK1,RPL13A,RPS3,SESN2,SPHK1,UPF1,ZFP36 |
| GO_NUCLEOTIDE_PHOSPHORYLATION | 1.5e-06 | 2.5e-05 | 1603 | 134 | 17 | AAAS,BPGM,ECD,EIF6,HDAC4,HK2,NME2,NUP54,NUP58,NUP88,NUP93,NUP98,PFKP,PGAM1,PNKP,PRKAA1,SEC13 |
| GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 1.5e-06 | 2.5e-05 | 1603 | 164 | 19 | ADAMTS1,ANAPC5,ANXA1,ASNS,AURKA,CDK4,EIF4EBP1,EPGN,EREG,FGF8,HES1,PAFAH1B1,PLRG1,RAD51B,RPS6KB1,SMPD3,SPHK1,TGFA,TMOD3 |
| GO_PROTEIN_ACYLATION | 1.6e-06 | 2.6e-05 | 1603 | 246 | 24 | BRPF1,DLST,GTF2B,JADE3,KAT2A,KAT8,MORF4L2,MRGBP,NAA15,NAA50,NAT9,NMT1,PHF20,PIH1D1,PIWIL2,POLE4,PRKAA1,RUVBL2,SELENOK,SGF29,SMARCB1,SPHK1,TAF1,ZNF451 |
| GO_REGULATION_OF_ATP_METABOLIC_PROCESS | 1.7e-06 | 2.8e-05 | 1603 | 121 | 16 | AAAS,ECD,EIF6,HDAC4,MTCO2P12,NUP54,NUP58,NUP88,NUP93,NUP98,PDE12,PGAM1,PID1,PRKAA1,SEC13,SHMT2 |
| GO_REGULATION_OF_CELL_CYCLE_ARREST | 1.7e-06 | 2.8e-05 | 1603 | 107 | 15 | AURKA,CDK4,CNOT1,CNOT7,E2F7,EVI2B,GADD45A,GATA6,HSP90AB1,PLK2,PLK3,PRMT1,RPL23,RPL26,TFAP4 |
| GO_RIBOSOMAL_LARGE_SUBUNIT_EXPORT_FROM_NUCLEUS | 1.7e-06 | 2.8e-05 | 1603 | 8 | 5 | NMD3,NPM1,NUP88,SDAD1,XPO1 |
| GO_ADP_METABOLIC_PROCESS | 1.9e-06 | 3.1e-05 | 1603 | 122 | 16 | AAAS,AK2,BPGM,ECD,EIF6,HDAC4,HK2,NUP54,NUP58,NUP88,NUP93,NUP98,PFKP,PGAM1,PRKAA1,SEC13 |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 1.9e-06 | 3.1e-05 | 1603 | 1071 | 64 | ABI2,ADAMTS1,AREG,ARL13B,BCAR3,CCDC66,CEP290,CNNM4,CRKL,DLX2,EMX2,EPHA2,EREG,ETV5,FGF8,FHL2,FOXC2,FOXF2,GATA6,GPC6,HCCS,HES1,HOXA3,IMPAD1,MAP2K1,MDFI,MKS1,MSX1,MTHFD1L,MYC,NECTIN1,NLE1,PAFAH1B1,PDGFA,PIM1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RP1,RPL38,SAPCD2,SEMA3A,SERP1,SERPINB5,SLIT2,SMPD3,SMURF2,SPRY2,STK40,TBX20,TNC,TNFRSF11B |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 1.9e-06 | 3.0e-05 | 1603 | 432 | 34 | ABI2,AIM2,ANKRD27,AP1AR,ARHGAP18,ARPC5L,BAIAP2L2,CARMIL2,COTL1,EIF2AK2,EIF4EBP1,HAX1,HSP90AA1,IDE,MAPK9,MAPRE1,NAPB,NAV3,NOP53,NR1H2,PFN2,PIH1D1,PMAIP1,PSMC5,PSRC1,RAC1,RACK1,RAP1B,RPL13A,RPS3,SLIT2,SUMO1,TBX20,TMOD3 |
| GO_LEUKOCYTE_MEDIATED_IMMUNITY | 2.0e-06 | 3.3e-05 | 1603 | 872 | 55 | ADGRG3,ADORA2B,ATAD3B,ATG7,ATP11B,BCL10,CAB39,CANT1,CCT2,CCT8,CD14,CD44,CEBPG,CEP290,CFP,COPB1,COTL1,CRACR2A,DDOST,DDX21,DHX36,EEF1A1,ERP44,FBXO38,HSP90AA1,HSP90AB1,IL23A,IL4R,ILF2,MASP2,NBN,NME2,PGAM1,PNP,PPIE,PRDX4,PSMA5,PSMB1,PSMD11,PSMD13,PSMD14,PSMD3,PSMD7,QSOX1,RAB24,RAB27A,RAC1,RAP1B,SHLD3,SNAP25,TBC1D10C,TFRC,TLR2,TXNDC5,XRCC6 |
| GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 2.0e-06 | 3.3e-05 | 1603 | 183 | 20 | CSNK1A1,DDIT3,EMD,G3BP1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RUVBL2,SIAH2 |
| GO_ATP_METABOLIC_PROCESS | 2.1e-06 | 3.4e-05 | 1603 | 303 | 27 | AAAS,AK2,BPGM,CLPX,COX10,COX4I1,ECD,EIF6,HDAC4,HK2,MTCO2P12,NADK,NDUFA5,NDUFB11,NUP54,NUP58,NUP88,NUP93,NUP98,OLA1,PDE12,PFKP,PGAM1,PID1,PRKAA1,SEC13,SHMT2 |
| GO_CELLULAR_RESPONSE_TO_LIPID | 2.1e-06 | 3.3e-05 | 1603 | 615 | 43 | ANXA1,BCL10,CBX3,CCL5,CD14,CDK4,CNOT1,CRY1,CXCL2,CXCL3,DDX18,EIF4EBP1,ESRRG,FHL2,GFI1,GRAMD1B,GRAMD1C,HAMP,IRAK2,KCTD6,MTDH,NME2,NR1D1,NR1D2,NR1H2,PDE4D,PID1,PIM1,PRKAA1,RPS6KB1,RUNX1,RUVBL2,RWDD1,SELENOS,TFAP4,TLR2,TNC,UBA5,UFM1,UFSP2,UPF1,URI1,ZFP36 |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 2.4e-06 | 3.8e-05 | 1603 | 767 | 50 | AGAP7P,AGAP9,AHSA1,AIM2,ANKRD27,ARF4,ARFGAP3,ARHGAP18,ARHGAP33,ARHGEF1,ARL1,BCL10,BLID,CCL20,CCL5,CLPX,CRKL,DOCK5,EPHA2,EZH2,FAS,FLT1,HSP90AB1,KARS1,LARS1,MYC,NET1,NR1H2,PDCD2,PDCD5,PFN2,PMAIP1,POT1,PSMD14,PSME4,RAB3GAP2,RACK1,RAP1GDS1,RAPGEF6,RGPD5,RGS17,RGS4,RGS5,RPS3,SEC23A,TBC1D10C,TBC1D14,TCEA1,TFAP4,WRN |
| GO_RESPONSE_TO_LEUKEMIA_INHIBITORY_FACTOR | 2.4e-06 | 3.8e-05 | 1603 | 96 | 14 | CTH,GCLM,GFPT2,HK2,MYNN,PFKP,PIGA,RFX2,RNMT,SPRY2,SRSF3,SRSF7,TEX14,TFRC |
| GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 2.4e-06 | 3.8e-05 | 1603 | 201 | 21 | BCL10,CACNA1F,CRKL,EIF2B2,PDE4D,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RPS3 |
| GO_NCRNA_EXPORT_FROM_NUCLEUS | 2.5e-06 | 3.9e-05 | 1603 | 38 | 9 | AAAS,NPM1,NUP54,NUP58,NUP88,NUP93,NUP98,SEC13,XPOT |
| GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 2.5e-06 | 3.9e-05 | 1603 | 154 | 18 | AAAS,AK2,BPGM,CASK,ECD,EIF6,HDAC4,HK2,NME2,NUP54,NUP58,NUP88,NUP93,NUP98,PFKP,PGAM1,PRKAA1,SEC13 |
| GO_NUCLEOTIDE_SUGAR_METABOLIC_PROCESS | 2.5e-06 | 3.9e-05 | 1603 | 38 | 9 | GFPT1,GFPT2,GNPDA1,GNPDA2,NANS,PGM3,PMM2,SLC35A3,UAP1 |
| GO_DRUG_METABOLIC_PROCESS | 2.6e-06 | 4.1e-05 | 1603 | 600 | 42 | AADAT,ADK,AHCYL1,AK2,ALDH18A1,ALDH8A1,ASNS,BHMT2,CD320,CTH,CYP2C19,DLST,DSE,DUOX2,GNPDA1,GNPDA2,HAAO,HSP90AA1,HSP90AB1,IDE,IL4I1,IREB2,METTL16,MMADHC,MTCO2P12,MTHFD1L,MTHFD2,MTR,MTRR,PAFAH1B1,PDXP,PHGDH,PID1,PRDX4,PSAT1,PYCR1,RAC1,SELENOS,SHMT2,SMS,TLR2,TMEM106A |
| GO_MATURATION_OF_LSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA | 2.6e-06 | 4.1e-05 | 1603 | 14 | 6 | BOP1,DDX18,GTPBP4,RPF2,RPL35,RPL7 |
| GO_PROTEIN_ACETYLATION | 2.6e-06 | 4.0e-05 | 1603 | 202 | 21 | BRPF1,GTF2B,JADE3,KAT2A,KAT8,MORF4L2,MRGBP,NAA15,NAA50,NAT9,PHF20,PIH1D1,PIWIL2,POLE4,PRKAA1,RUVBL2,SGF29,SMARCB1,SPHK1,TAF1,ZNF451 |
| GO_REGULATION_OF_RIBOSOME_BIOGENESIS | 2.6e-06 | 4.1e-05 | 1603 | 14 | 6 | BUD23,DIMT1,RIOK1,RIOK2,UTP15,WDR43 |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 2.7e-06 | 4.3e-05 | 1603 | 622 | 43 | AGO3,AMER3,CSNK1A1,CSNK1G3,CSNK2A1,DDIT3,EMD,G3BP1,GPC6,GRB10,HMGXB4,MARK2,MDFI,MKS1,NETO1,NLE1,OTULIN,PPP2CA,PRKAA1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RACK1,RGS4,RPS27A,RUNX1,RUVBL2,SIAH2,SMURF2,TLR2,UBA52 |
| GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | 2.7e-06 | 4.2e-05 | 1603 | 84 | 13 | MEIOC,METTL16,NBAS,NOCT,NPM1,SAP18,SRSF7,TARDBP,TENT4B,U2AF2,YBX1,YBX3,ZFP36 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 2.9e-06 | 4.5e-05 | 1603 | 561 | 40 | AHCYL1,ANXA1,ANXA5,ANXA7,AREG,ARL13B,ATG7,CD14,CDK4,CPNE5,DHX36,EIF2S1,EZH2,FOSB,FOSL1,GCLC,GLRX2,HAAO,HAMP,LONP1,MAPK9,MNAT1,MT2A,MTF1,MTR,NET1,NEUROD2,NUDT1,PPP2CA,PRKAA1,PRNP,PYCR1,RACK1,RPS3,SMPD3,SUMO1,TNFRSF11B,TRAP1,TXN,ZFAND1 |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 3.2e-06 | 4.9e-05 | 1603 | 423 | 33 | AAAS,AADAT,ACBD6,ACOT7,ACOT9,ADK,AK2,BPGM,CASK,DLST,ECD,EFL1,EIF6,EPHA2,FAR1,GNAI3,GTPBP1,HDAC4,HK2,IMPAD1,MTCO2P12,NME2,NUP54,NUP58,NUP88,NUP93,NUP98,PDE4D,PFKP,PGAM1,PID1,PRKAA1,SEC13 |
| GO_CELL_GROWTH | 3.3e-06 | 5.1e-05 | 1603 | 483 | 36 | ARIH2,AURKA,BIN3,C9orf72,CDH4,CDK11B,CIB1,CPNE5,CRKL,CSNK2A1,FSTL4,GOLGA4,HAMP,HBEGF,HSP90AA1,HSP90AB1,ING1,MSX1,NET1,NPM1,NUBP1,OSGIN1,OSGIN2,PAFAH1B1,PAK4,PPP2CA,PSRC1,RACK1,RAPH1,RGS4,SEMA3A,SESN2,SGK3,SLIT2,SPHK1,URI1 |
| GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 3.3e-06 | 5.1e-05 | 1603 | 157 | 18 | AAAS,ECD,EIF6,HDAC4,IDE,NOP53,NUP54,NUP58,NUP88,NUP93,NUP98,PDE12,PGAM1,PRKAA1,SEC13,SELENOS,SHMT2,TRAP1 |
| GO_RESPONSE_TO_STARVATION | 3.3e-06 | 5.2e-05 | 1603 | 189 | 20 | ASNS,ATF3,ATG7,DDIT3,EIF2AK2,EIF2S1,EIF4EBP1,FAS,HAMP,KLF10,LARS1,MARS1,MAX,PMAIP1,PPM1D,PRKAA1,SESN2,TBL2,WRN,ZFP36 |
| GO_RHYTHMIC_PROCESS | 3.5e-06 | 5.4e-05 | 1603 | 293 | 26 | ADAMTS1,ATG7,CBX3,CDK4,CREM,CRY1,CSNK2A1,EREG,EZH2,GFPT1,HTR7,KLF10,MAPK9,NAMPT,NFYA,NOCT,NR1D1,NR1D2,PIWIL2,PRKAA1,PRMT5,RACK1,SIAH2,SLIT2,SRRD,TARDBP |
| GO_DNA_INTEGRITY_CHECKPOINT | 3.6e-06 | 5.5e-05 | 1603 | 158 | 18 | AURKA,BRSK1,CNOT1,CNOT7,CRY1,E2F7,GADD45A,HUS1,NBN,NOP53,PLK2,PLK3,PRMT1,RAD9A,RHNO1,RINT1,RPL26,TIPIN |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 3.6e-06 | 5.6e-05 | 1603 | 1047 | 62 | ADAMTS9,ANXA1,AP1AR,AREG,CIB1,DDIT3,DICER1,DLX2,EPHA2,EREG,EZH2,FGF8,FOXA2,FOXC2,FSTL4,GAK,GDF15,GFI1,H4C2,H4C3,H4C4,HDAC4,HES1,IL4R,MSX1,MYC,NAMPT,NEUROD2,NIBAN2,NME2,NOCT,NR1D1,NR1H2,PAFAH1B1,PAQR3,PLK2,PPP2CA,PRMT1,PRMT5,RFX8,RGS4,RUNX1,SARS1,SEMA3A,SFMBT1,SLIT2,SPRED1,SPRY2,STC2,TLR2,TMEM98,TNFRSF11B,TRIB2,TRIB3,TRIM11,UBASH3B,VAX1,WDR77,YBX1,YBX3,ZC3H8,ZFP36 |
| GO_MITOCHONDRIAL_TRANSPORT | 3.7e-06 | 5.6e-05 | 1603 | 258 | 24 | ARIH2,DNLZ,GCLC,HAX1,HK2,HSP90AA1,HSPA4,LMAN1,MICU2,NMT1,PAM16,PDCD5,PITRM1,PMAIP1,PRKAA1,PRKAB2,SLC25A14,SLC25A6,TIMM13,TIMM23B,TIMM9,TOMM20,TOMM34,YWHAE |
| GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 3.8e-06 | 5.9e-05 | 1603 | 22 | 7 | MSX1,PMAIP1,RPL11,RPL23,RPL26,SPRED1,SPRED2 |
| GO_RRNA_BASE_METHYLATION | 3.8e-06 | 5.8e-05 | 1603 | 9 | 5 | BUD23,EMG1,METTL16,NOP2,NSUN5 |
| GO_DNA_GEOMETRIC_CHANGE | 3.9e-06 | 5.9e-05 | 1603 | 114 | 15 | ANXA1,CHTF8,DHX36,G3BP1,HMGA1,MNAT1,NBN,POT1,RAD23B,RPS27A,RUVBL2,UBA52,WRN,XRCC6,ZRANB3 |
| GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 3.9e-06 | 5.9e-05 | 1603 | 259 | 24 | ADORA2B,CRKL,DUSP5,DUSP6,DUSP7,EIF2AK2,EPGN,EZH2,FLT1,GADD45A,GDF15,IRAK2,KARS1,MAP2K1,MAP3K21,MAP3K4,MAPKAPK3,MAPKAPK5,PDGFA,PRKAA1,RPS27A,RPS3,TGFA,UBA52 |
| GO_MULTI_ORGANISM_LOCALIZATION | 4.0e-06 | 6.1e-05 | 1603 | 62 | 11 | AAAS,NUP54,NUP58,NUP88,NUP93,NUP98,RPS27A,SEC13,TCP1,UBA52,XPO1 |
| GO_EXECUTION_PHASE_OF_APOPTOSIS | 4.1e-06 | 6.1e-05 | 1603 | 87 | 13 | DFFA,DICER1,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,PAM16,RFFL,RPS3 |
| GO_RESPONSE_TO_IONIZING_RADIATION | 4.1e-06 | 6.2e-05 | 1603 | 144 | 17 | AEN,ANXA1,EEF1D,GADD45A,HAMP,HUS1,IKBIP,KARS1,MYC,NAMPT,NET1,PRKAA1,RAD9A,RHNO1,RPL26,WRN,XRCC6 |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEOLUS | 4.2e-06 | 6.3e-05 | 1603 | 15 | 6 | BYSL,NMD3,NOP53,NPM1,RPF2,WRN |
| GO_NUCLEUS_ORGANIZATION | 4.5e-06 | 6.8e-05 | 1603 | 130 | 16 | BANF1,EMD,EMG1,NOLC1,NUP54,NUP93,NUP98,PAFAH1B1,PIWIL1,PPP2CA,PPP2R2A,PSME4,RPS19,SUMO1,TARDBP,WBP2NL |
| GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION | 4.6e-06 | 6.9e-05 | 1603 | 75 | 12 | MNAT1,POLR1E,POLR2H,PRMT5,SMN1,SMN2,TAF1A,TAF1D,TBP,WDR33,XRN2,ZNF473 |
| GO_ALPHA_AMINO_ACID_BIOSYNTHETIC_PROCESS | 4.7e-06 | 7.1e-05 | 1603 | 63 | 11 | ALDH18A1,ASNS,BCAT1,BHMT2,CTH,MTR,MTRR,PHGDH,PSAT1,PYCR1,SHMT2 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 4.7e-06 | 7.1e-05 | 1603 | 63 | 11 | CHAC1,CREB3,DDIT3,HERPUD1,ITPR1,PMAIP1,SELENOK,SELENOS,SYVN1,TMBIM6,TRIB3 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 4.8e-06 | 7.1e-05 | 1603 | 853 | 53 | ACRBP,ADAMTS1,AURKA,CCDC36,CDK16,CIB1,CREM,CRKL,DDX20,DHX36,EIF2S2,EIF5A2,EREG,ETV5,FAM9C,FOSL1,HDAC4,HERC4,IL4R,MEIOC,OR7C1,PAFAH1B1,PAIP2,PAQR5,PGM3,PHC2,PIWIL1,PIWIL2,PLD6,PRDM14,PRDX4,PSME4,RAD23B,RFX2,RNF114,RNF2,RPS6,RPS6KB1,SFMBT1,SHCBP1L,SLIT2,SMAD5,SPATA2,SPATA5,SPIN2A,STC2,TAF4B,TBP,TEX14,USP42,WDR33,XRN2,YBX3 |
| GO_MEIOTIC_CELL_CYCLE | 5.0e-06 | 7.4e-05 | 1603 | 245 | 23 | AURKA,CCDC36,EREG,EXD1,FAM9C,FBXO43,GPR3,HUS1,MEIOC,MSX1,NBN,OSGIN2,PIWIL1,PIWIL2,PLD6,PPP2CA,PSMD13,RAD51B,SHCBP1L,TERB2,TEX14,WBP2NL,ZW10 |
| GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 5.4e-06 | 8.0e-05 | 1603 | 147 | 17 | CSNK1G3,NLE1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,SMURF2 |
| GO_RESPONSE_TO_CARBOHYDRATE | 5.4e-06 | 8.1e-05 | 1603 | 229 | 22 | ATG7,CDK16,EIF2B2,ENY2,FOXA2,GCLC,GCLM,NADK,NAMPT,NDUFAF2,NME2,NR1D1,PIH1D1,PRKAA1,RAC1,RACK1,RAP1B,RPS6KB1,SELENOS,SESN2,SLC9B2,SMARCB1 |
| GO_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS | 6.0e-06 | 8.8e-05 | 1603 | 118 | 15 | AAAS,ADORA2B,ECD,EIF6,HDAC4,MTCO2P12,NUP54,NUP58,NUP88,NUP93,NUP98,PGAM1,PID1,PRKAA1,SEC13 |
| GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION | 6.1e-06 | 9.0e-05 | 1603 | 133 | 16 | AURKA,BRSK1,C10orf90,CEP85,GADD45A,KAT2A,NPM1,NUBP1,PAFAH1B1,PDCD6IP,PLK2,RTTN,SLC16A1,TUBE1,UXT,XPO1 |
| GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY | 6.1e-06 | 8.9e-05 | 1603 | 77 | 12 | CNOT1,CNOT7,DHX36,EDC3,EXOSC1,HBS1L,LSM5,NOCT,PDE12,SKIV2L,TENT4B,ZFP36 |
| GO_RNA_STABILIZATION | 6.2e-06 | 9.1e-05 | 1603 | 53 | 10 | DHX36,MEIOC,METTL16,NOCT,TARDBP,TENT2,TENT4B,YBX1,YBX3,ZFP36 |
| GO_METAL_ION_TRANSPORT | 6.3e-06 | 9.2e-05 | 1603 | 906 | 55 | ABCB11,ABCC9,AHCYL1,ALG10B,ANXA5,CAB39,CACNA1F,CASK,CBARP,CCL5,CNNM4,CRACR2A,CUTC,DDIT3,EPB41,EPPIN,HAMP,HOMER2,IREB2,ITPR1,KCNG1,KCNG4,KCNK1,KCNQ5,LILRA5,MICU2,NECTIN1,NETO1,NIPAL4,PANX1,PDE4D,PKD2L2,PRNP,RGS4,SEC61A1,SELENOK,SLC10A5,SLC31A1,SLC39A6,SLC39A7,SLC6A15,SLC9B2,SNAP25,STAC,STC2,SUMO1,TFRC,TMBIM6,TMC2,TMEM38B,TPT1,UBASH3B,UBQLN1,YME1L1,YWHAE |
| GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 6.5e-06 | 9.6e-05 | 1603 | 181 | 19 | CSNK1G3,CSNK2A1,NLE1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,SMURF2,TLR2 |
| GO_PYRUVATE_METABOLIC_PROCESS | 7.1e-06 | 1.0e-04 | 1603 | 150 | 17 | AAAS,BPGM,ECD,EIF6,GLO1,HDAC4,HK2,NUP54,NUP58,NUP88,NUP93,NUP98,PFKP,PGAM1,PRKAA1,SEC13,SLC16A1 |
| GO_ENDONUCLEOLYTIC_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING | 7.4e-06 | 1.1e-04 | 1603 | 10 | 5 | ABT1,BOP1,NOP14,RPS21,UTP23 |
| GO_TRANSCRIPTION_PREINITIATION_COMPLEX_ASSEMBLY | 7.4e-06 | 1.1e-04 | 1603 | 43 | 9 | GTF2B,PIH1D1,POLR1E,PSMC5,SGF29,SMARCB1,TAF1,TAF6,TBP |
| GO_VESICLE_BUDDING_FROM_MEMBRANE | 7.7e-06 | 1.1e-04 | 1603 | 106 | 14 | AREG,ARFGAP3,GOLPH3L,GOSR2,LMAN1,MCFD2,SEC13,SEC23A,SEC24A,SEC24D,TFG,TGFA,TMED9,TRAPPC6B |
| GO_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR | 7.8e-06 | 1.1e-04 | 1603 | 151 | 17 | CCL5,CD44,CRKL,FGF8,GCLC,GCLM,IER2,POLR2C,POLR2H,POLR2J,PRDM14,SPRED1,SPRED2,SPRY2,SPRY4,TNC,ZFP36 |
| GO_STEM_CELL_DIFFERENTIATION | 7.9e-06 | 1.1e-04 | 1603 | 252 | 23 | DHX36,EIF2AK2,FOXC2,GATA6,HES1,MSX1,NOLC1,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RUNX1,SEMA3A |
| GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 8.0e-06 | 1.2e-04 | 1603 | 79 | 12 | DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,PAQR3,PPP2CA,RGS4,SPRED1,SPRED2,SPRY2,SPRY4 |
| GO_ACTIVATION_OF_MAPK_ACTIVITY | 8.5e-06 | 1.2e-04 | 1603 | 152 | 17 | ADORA2B,CRKL,DUSP5,DUSP6,DUSP7,EPGN,GDF15,IRAK2,KARS1,MAP2K1,MAP3K21,MAPKAPK3,MAPKAPK5,PRKAA1,RPS27A,TGFA,UBA52 |
| GO_PEPTIDYL_LYSINE_ACETYLATION | 8.5e-06 | 1.2e-04 | 1603 | 168 | 18 | BRPF1,GTF2B,JADE3,KAT2A,KAT8,MORF4L2,MRGBP,NAA50,PHF20,PIH1D1,PIWIL2,POLE4,PRKAA1,RUVBL2,SGF29,SMARCB1,TAF1,ZNF451 |
| GO_NEUROGENESIS | 8.6e-06 | 1.2e-04 | 1603 | 1625 | 85 | ABI2,ABT1,ANKRD27,ANXA1,AREG,ARF4,ARHGAP33,ATL1,AURKA,BRSK1,C9orf72,CCDC66,CDH4,CDK16,CEP290,CHAC1,CIB1,CPNE5,CRKL,DGKG,DHX36,DICER1,DLX2,EIF2B2,EMX2,EN2,EPHA2,ETV5,EZH2,FBXO38,FGF8,FOXA2,FSTL4,GAK,GFI1,GOLGA4,GRB10,HES1,HSP90AA1,HSP90AB1,IER2,KATNB1,KIRREL3,MAP2K1,MARK2,MKS1,MOB2,MTR,MYT1L,NAV3,NBL1,NECTIN1,NEUROD2,NIBAN2,NIF3L1,NME2,NR1D1,PAFAH1B1,PAK4,PAQR3,PHGDH,PLK2,PRMT1,PRMT5,RAC1,RAPH1,RHEB,RP1,RPL24,RUNX1,SEMA3A,SLIT2,SNAP25,SS18L1,TBX20,TENT2,TLR2,TMEM98,TNC,TRIM11,UBE2V2,VAX1,XRN2,YWHAE,ZNF609 |
| GO_COENZYME_METABOLIC_PROCESS | 9.0e-06 | 1.3e-04 | 1603 | 254 | 23 | AADAT,ACBD6,ACOT7,ACOT9,AHCYL1,BHMT2,COQ10B,COQ6,DLST,FAR1,GCLC,HAAO,LIAS,METTL16,MMADHC,MTHFD1L,MTHFD2,MTRR,NADK,NAMPT,PDXP,SHMT2,UBIAD1 |
| GO_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | 9.0e-06 | 1.3e-04 | 1603 | 674 | 44 | BCL10,BTLA,CACNA1F,CD14,CRKL,DMBT1,EIF2B2,GFI1,HSP90AA1,HSP90AB1,ICAM3,IRAK2,MAPK9,MAPKAPK3,MFHAS1,NOP53,NR1D1,OTULIN,PDE4D,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RPS27A,RPS3,RUNX1,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1 |
| GO_CELLULAR_RESPONSE_TO_UV | 9.1e-06 | 1.3e-04 | 1603 | 80 | 12 | CERS1,DHX36,EIF2S1,MYC,N4BP1,NPM1,PPID,RHNO1,RPL26,RUVBL2,TAF1,TMEM161A |
| GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 9.6e-06 | 1.4e-04 | 1603 | 273 | 24 | BCL10,CANT1,CD14,CTH,DDX21,DHX36,EDA2R,EEF1D,GOLT1B,IRAK2,LURAP1L,MTDH,NR1D1,OTUD7A,PELI2,PIM2,PLK2,PRDX4,RPS27A,TBK1,TFG,TLR2,TMEM106A,UBA52 |
| GO_ACTIVATION_OF_IMMUNE_RESPONSE | 9.8e-06 | 1.4e-04 | 1603 | 720 | 46 | AIM2,BCL10,CACNA1F,CD14,CFP,CRKL,DMBT1,EIF2B2,GFI1,HSP90AA1,HSP90AB1,ICAM3,IRAK2,MAPKAPK3,MASP2,MFHAS1,NOP53,NR1D1,OTULIN,PDE4D,PRNP,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1,RPS27A,RPS3,RUNX1,TBK1,TLR2,TRAF3,UBA52,UBE2D2,UBQLN1,XRCC6 |
| GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS | 1.0e-05 | 1.5e-04 | 1603 | 81 | 12 | ALDH18A1,ASNS,BCAT1,BHMT2,CTH,GPT2,MTR,MTRR,PHGDH,PSAT1,PYCR1,SHMT2 |
| GO_DEVELOPMENTAL_GROWTH | 1.0e-05 | 1.4e-04 | 1603 | 677 | 44 | ANXA1,APBA1,AREG,ARIH2,AURKA,BIN3,C9orf72,CDH4,CDK4,CPNE5,DUSP6,EIF4H,EREG,EZH2,FGF8,FOXC2,FSTL4,GATA6,GDF15,GOLGA4,HAMP,HSP90AA1,HSP90AB1,KAT2A,NBN,PAFAH1B1,PDE4D,PELO,PIM1,RAPH1,RGS4,RPS6KB1,SEMA3A,SERP1,SLC1A2,SLIT2,SMPD3,SPRY2,STC2,STK40,TBX20,TMEM38B,TNC,YBX3 |
| GO_NEGATIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 1.1e-05 | 1.5e-04 | 1603 | 171 | 18 | ADGRG3,AIM2,CEBPG,DDIT3,EZH2,FOXA2,G3BP2,GFI1,HDAC4,IRAK2,MDFI,OTULIN,PIM1,PRNP,RNF2,SUMO1,TAF1,TRAF3 |
| GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION | 1.2e-05 | 1.7e-04 | 1603 | 69 | 11 | EEF1D,GADD45A,HAMP,HUS1,NAMPT,NET1,RAD9A,RHNO1,RPL26,WRN,XRCC6 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 1.3e-05 | 1.9e-04 | 1603 | 111 | 14 | ELOC,ELP2,ENY2,EZH2,MNAT1,POLR1E,POLR2C,POLR2H,POLR2J,TAF1A,TAF1D,TBP,TCEA1,WDR43 |
| GO_NEGATIVE_REGULATION_OF_RNA_SPLICING | 1.3e-05 | 1.9e-04 | 1603 | 26 | 7 | NPM1,PTBP2,RPS13,SAP18,SRSF7,TMBIM6,U2AF2 |
| GO_NEURON_DEVELOPMENT | 1.3e-05 | 1.8e-04 | 1603 | 1114 | 63 | ABI2,ANKRD27,AREG,ARF4,ARHGAP33,ATL1,AURKA,BRSK1,C9orf72,CCDC66,CDH4,CDK16,CEP290,CIB1,CPNE5,CRKL,DGKG,DHX36,DICER1,EN2,EPHA2,EZH2,FBXO38,FGF8,FSTL4,GAK,GFI1,GOLGA4,GRB10,HES1,HSP90AA1,HSP90AB1,KATNB1,KIRREL3,MAP2K1,MARK2,MKS1,MOB2,MTR,MYT1L,NBL1,NECTIN1,NEUROD2,NIBAN2,NME2,PAFAH1B1,PAK4,PAQR3,PHGDH,PLK2,PRMT1,RAC1,RAPH1,RP1,RPL24,RUNX1,SEMA3A,SLIT2,SNAP25,SS18L1,TNC,UBE2V2,VAX1 |
| GO_RESPONSE_TO_LIPID | 1.3e-05 | 1.8e-04 | 1603 | 930 | 55 | ANXA1,AREG,BCL10,CBX3,CCL5,CD14,CDK4,CNOT1,CRY1,CXCL2,CXCL3,DDX18,EIF4EBP1,ESRRG,EZH2,FHL2,FOSB,FOSL1,GFI1,GRAMD1B,GRAMD1C,HAMP,IRAK2,KCTD6,LIAS,MAPKAPK3,MTDH,NME2,NOCT,NR1D1,NR1D2,NR1H2,OVCA2,PDE4D,PID1,PIM1,PRKAA1,RPS6KB1,RUNX1,RUVBL2,RWDD1,SELENOS,SLIT2,STC2,TFAP4,TLR2,TMEM161A,TNC,TYR,UBA5,UFM1,UFSP2,UPF1,URI1,ZFP36 |
| GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 1.3e-05 | 1.9e-04 | 1603 | 297 | 25 | ADORA2B,COPS5,CRKL,EDA2R,EIF2AK2,FAS,GADD45A,IRAK2,KARS1,KLHDC10,MAP2K1,MAP3K21,MAP3K4,MAPK9,MFHAS1,MYC,PAFAH1B1,PRMT1,RELL1,RPS27A,RPS3,SEMA3A,SPHK1,UBA52,ZFP36 |
| GO_GOLGI_ORGANIZATION | 1.4e-05 | 2.0e-04 | 1603 | 142 | 16 | ARL1,COG1,CSNK1A1,DYM,GAK,GOLGA8A,GOLGA8B,GOLPH3L,LMAN1,MAP2K1,PLK3,PRMT5,RAB2A,TMED1,TMED9,ZW10 |
| GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 1.4e-05 | 1.9e-04 | 1603 | 394 | 30 | ANKRD27,ASF1A,CARMIL2,CEP97,CIB1,FBXO43,GCLC,HMGA1,KAT2A,KATNB1,LMAN1,MAPRE1,MNAT1,NAV3,NBN,NPM1,NUBP1,PAM16,PFN2,PIH1D1,POT1,PPFIA1,SLIT2,SMARCB1,TENT4B,TEX14,TMOD3,ZNF207,ZNF451,ZW10 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 1.4e-05 | 2.0e-04 | 1603 | 243 | 22 | ABI2,AIM2,AP1AR,ARPC5L,BAIAP2L2,CARMIL2,HSP90AA1,IDE,MAPK9,MAPRE1,NAV3,NR1H2,PFN2,PIH1D1,PMAIP1,PSMC5,PSRC1,RAC1,RACK1,RAP1B,RPS3,SUMO1 |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 1.4e-05 | 2.0e-04 | 1603 | 687 | 44 | ABI2,ANKRD27,ARHGAP33,BIN3,BRSK1,CARMIL2,CD44,CDH4,CEP97,CIB1,CPNE5,CRKL,DHX36,DYNC2LI1,EPHA2,EZH2,FBXO38,FSTL4,GAK,GFI1,GOLGA4,HDAC4,KAT2A,KATNB1,MAP2K1,MARK2,MOB2,NAV3,NME2,PAFAH1B1,PAQR3,PFN2,PLEK2,PLK2,PRNP,RAC1,RP1,SEMA3A,SLIT2,SNAP25,SPRY2,SS18L1,UBE2V2,ZMYND10 |
| GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS | 1.5e-05 | 2.1e-04 | 1603 | 244 | 22 | ANKRD54,ANXA1,BCL10,BPGM,CACNA1F,CEBPG,EZH2,IREB2,MFHAS1,NLE1,PMAIP1,PRDM14,PRMT1,RHEX,RPS14,RPS19,RPS24,RPS6,SMAD5,TMOD3,ZC3H8,ZFP36 |
| GO_MRNA_3_END_PROCESSING | 1.5e-05 | 2.1e-04 | 1603 | 98 | 13 | AHCYL1,DDX39A,DHX36,MAGOH,SRSF1,SRSF3,SRSF7,TENT4B,THOC6,U2AF1,U2AF2,WDR33,ZNF473 |
| GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 1.6e-05 | 2.3e-04 | 1603 | 499 | 35 | ANXA5,CACNA1F,CASK,CBARP,CCL5,CNNM4,CRACR2A,DDIT3,EPB41,EPPIN,HOMER2,ITPR1,LILRA5,MICU2,NIPAL4,PANX1,PDE4D,PKD2L2,PRNP,RGS4,SEC61A1,SELENOK,SLC39A6,SLC39A7,STAC,STC2,SUMO1,TMBIM6,TMC2,TMEM38B,TPT1,UBASH3B,UBQLN1,YME1L1,YWHAE |
| GO_NEGATIVE_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 1.7e-05 | 2.3e-04 | 1603 | 59 | 10 | CNRIP1,IL18BP,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8 |
| GO_LOCOMOTION | 1.8e-05 | 2.5e-04 | 1603 | 1984 | 98 | ABI2,ADAMTS1,ADAMTS9,ADGRG3,AIMP1,ANXA1,ANXA5,AP1AR,ARF4,ARHGAP18,ARL13B,ARPC5L,BIN3,C5orf30,CARMIL2,CCL20,CCL5,CCSAP,CD44,CDH4,CIB1,CKLF,CMTM7,CMTM8,CREB3,CRKL,CXCL2,CXCL3,DOCK5,DUOX2,EMX2,EPHA2,EPPIN,EREG,FGF8,FLT1,FOSL1,FOXC2,GPC6,GRB10,GTPBP4,HBEGF,HDAC4,HES1,HRH1,IER2,IL23A,INTS13,KARS1,KIRREL3,LDB2,MAP2K1,MAPRE1,MARK2,NAV3,NBL1,NECTIN1,NET1,NIBAN2,NUS1,OSGIN1,PAFAH1B1,PAK4,PDE4D,PDGFA,PFN2,PLK2,PPID,PRDM14,RAC1,RACK1,RFFL,RFX3,RPL24,RPS19,RPS6KB1,SELENOK,SEMA3A,SGK3,SLC16A1,SLC7A5,SLC7A9,SLC9B2,SLIT2,SMPD3,SMURF2,SPATA13,SPHK1,SPRED1,SPRY2,SRGAP2B,STRIP2,SVBP,TBX20,TRIM11,VAX1,YWHAE,ZNF609 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 1.8e-05 | 2.5e-04 | 1603 | 145 | 16 | CIB1,DUSP2,DUSP4,DUSP5,DUSP6,DUSP7,IPO5,PAQR3,PPP2CA,PRKAR1B,RGS4,SPRED1,SPRED2,SPRY2,SPRY4,TFAP4 |
| GO_NEURON_DIFFERENTIATION | 1.8e-05 | 2.5e-04 | 1603 | 1365 | 73 | ABI2,ABT1,ANKRD27,AREG,ARF4,ARHGAP33,ATL1,AURKA,BRSK1,C9orf72,CCDC66,CDH4,CDK16,CEP290,CIB1,CPNE5,CRKL,DGKG,DHX36,DICER1,DLX2,EMX2,EN2,EPHA2,ETV5,EZH2,FBXO38,FGF8,FOXA2,FSTL4,GAK,GFI1,GOLGA4,GRB10,HES1,HSP90AA1,HSP90AB1,IER2,KATNB1,KIRREL3,MAP2K1,MARK2,MKS1,MOB2,MTR,MYT1L,NBL1,NECTIN1,NEUROD2,NIBAN2,NIF3L1,NME2,PAFAH1B1,PAK4,PAQR3,PHGDH,PLK2,PRMT1,RAC1,RAPH1,RP1,RPL24,RUNX1,SEMA3A,SLIT2,SNAP25,SS18L1,TBX20,TENT2,TNC,UBE2V2,VAX1,XRN2 |
| GO_REGULATION_OF_CIRCADIAN_RHYTHM | 1.8e-05 | 2.5e-04 | 1603 | 114 | 14 | ATG7,CREM,CRY1,EZH2,KLF10,MAPK9,NOCT,NR1D1,NR1D2,PIWIL2,PRKAA1,SIAH2,SRRD,TARDBP |
| GO_REGULATION_OF_REPRODUCTIVE_PROCESS | 1.8e-05 | 2.5e-04 | 1603 | 161 | 17 | ANXA5,AURKA,CCDC36,CIB1,EPPIN,FBXO43,GPR3,HDAC4,INTS13,MEIOC,MSX1,PIWIL2,PRDM14,PRDX4,SEMA3A,SMURF2,WDR77 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 1.8e-05 | 2.5e-04 | 1603 | 440 | 32 | AADAT,ABHD10,ALDH8A1,APOBEC3A,APOBEC3D,BCAT1,BLMH,BPGM,CD44,CTH,DLST,FUT2,FUT9,GLYATL2,GNPDA1,GNPDA2,GPT2,HAAO,HACL1,HK2,IL4I1,IMPA1,MTRR,NT5C,NUDT1,PDXP,PFKP,PGAM1,PNP,PON3,SESN2,SHMT2 |
| GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_I_PROMOTER | 1.8e-05 | 2.5e-04 | 1603 | 37 | 8 | MNAT1,PIH1D1,POLR1E,POLR2H,SMARCB1,TAF1A,TAF1D,TBP |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 1.9e-05 | 2.6e-04 | 1603 | 100 | 13 | CEBPG,MMS19,MSX1,MYC,PMAIP1,RAD9A,RPL26,RPS3,SHLD3,SPRED1,SPRED2,TMEM161A,UBE2V2 |
| GO_AGING | 2.0e-05 | 2.7e-04 | 1603 | 323 | 26 | ATG7,CANX,DNMBP,EIF2S1,GCLC,GCLM,GLRX2,HAMP,HMGA1,IDE,LONP1,MAP2K1,MAPKAPK5,MORC3,NAMPT,NPM1,NUDT1,PDE4D,PLK2,PRNP,RPS6KB1,RSL1D1,RWDD1,SERP1,SLC1A2,WRN |
| GO_CELLULAR_RESPONSE_TO_STARVATION | 2.0e-05 | 2.7e-04 | 1603 | 146 | 16 | ASNS,ATF3,ATG7,EIF2AK2,EIF2S1,FAS,KLF10,LARS1,MARS1,MAX,PMAIP1,PPM1D,PRKAA1,SESN2,TBL2,WRN |
| GO_COPII_COATED_VESICLE_BUDDING | 2.0e-05 | 2.8e-04 | 1603 | 73 | 11 | AREG,GOSR2,LMAN1,MCFD2,SEC13,SEC23A,SEC24A,SEC24D,TFG,TGFA,TRAPPC6B |
| GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR | 2.0e-05 | 2.8e-04 | 1603 | 73 | 11 | COPS5,LIG3,MNAT1,POLD2,POLR2C,POLR2H,POLR2J,PPIE,RPS27A,TCEA1,UBA52 |
| GO_CATION_TRANSPORT | 2.1e-05 | 2.8e-04 | 1603 | 1180 | 65 | ABCB11,ABCC9,AHCYL1,ALG10B,ANXA5,CAB39,CACNA1F,CASK,CBARP,CCL5,CNNM4,COX10,COX4I1,CRACR2A,CUTC,DDIT3,EPB41,EPPIN,HAMP,HOMER2,IREB2,ITPR1,KCNG1,KCNG4,KCNK1,KCNQ5,LILRA5,MICU2,MTCO2P12,NECTIN1,NETO1,NIPAL4,PANX1,PDE4D,PKD2L2,PRNP,RGS4,RHBG,RHD,SEC61A1,SELENOK,SLC10A5,SLC1A5,SLC25A14,SLC31A1,SLC36A4,SLC39A6,SLC39A7,SLC6A15,SLC7A1,SLC7A5,SLC9B2,SNAP25,STAC,STC2,SUMO1,TFRC,TMBIM6,TMC2,TMEM38B,TPT1,UBASH3B,UBQLN1,YME1L1,YWHAE |
| GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 2.2e-05 | 3.0e-04 | 1603 | 180 | 18 | ATF3,BCL10,DDIT3,FAS,MAPK9,MCL1,MSX1,NMT1,PDCD5,PDIA3,PMAIP1,RACK1,RAD9A,RPL11,RPL26,RPS3,TFAP4,YWHAE |
| GO_REGULATION_OF_CARBOHYDRATE_CATABOLIC_PROCESS | 2.2e-05 | 2.9e-04 | 1603 | 87 | 12 | AAAS,ECD,EIF6,HDAC4,NUP54,NUP58,NUP88,NUP93,NUP98,PGAM1,PRKAA1,SEC13 |
| GO_IMPORT_INTO_NUCLEUS | 2.3e-05 | 3.1e-04 | 1603 | 164 | 17 | DDX20,IPO5,NOLC1,NUP54,NUP58,NUP88,NUP93,NUP98,NXT2,RGPD5,RPL23,SMN1,SMN2,SNUPN,SPRN,TARDBP,TNPO3 |
| GO_TOXIN_TRANSPORT | 2.3e-05 | 3.0e-04 | 1603 | 38 | 8 | CCT2,CCT3,CCT4,CCT5,CCT7,CCT8,COPB2,TCP1 |
| GO_CARBOHYDRATE_CATABOLIC_PROCESS | 2.4e-05 | 3.1e-04 | 1603 | 198 | 19 | AAAS,ABHD10,BPGM,ECD,EIF6,FUT2,FUT9,HDAC4,HK2,NUP54,NUP58,NUP88,NUP93,NUP98,PFKP,PGAM1,PHKG1,PRKAA1,SEC13 |
| GO_CARBOHYDRATE_TRANSPORT | 2.4e-05 | 3.2e-04 | 1603 | 148 | 16 | ERFE,GRB10,HK2,MFSD2A,MFSD2B,PID1,RPS6KB1,SELENOS,SESN2,SLC1A2,SLC35A2,SLC35A3,SLC35D2,SLC37A3,SMPD3,TRIB3 |
| GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | 2.4e-05 | 3.2e-04 | 1603 | 148 | 16 | AIM2,BCL10,CIB1,CTH,EDA2R,EIF2AK2,IRAK2,MTDH,NPM1,PSMA6,RHEBL1,RPS27A,RPS3,SPHK1,TLR2,UBA52 |
| GO_FERTILIZATION | 2.6e-05 | 3.4e-04 | 1603 | 182 | 18 | AAAS,ACRBP,CCT2,CCT3,CCT4,CCT5,CCT7,CCT8,CRKL,GNPDA1,INTS13,PRDM14,SNU13,SPAG1,TCP1,TRIM36,WBP2NL,YBX3 |
| GO_PROTEIN_INSERTION_INTO_MEMBRANE | 2.6e-05 | 3.5e-04 | 1603 | 62 | 10 | GET4,HSP90AA1,HSPA4,NMT1,PDCD5,PMAIP1,TIMM13,TIMM9,UBL4A,YWHAE |
| GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 2.6e-05 | 3.5e-04 | 1603 | 217 | 20 | CD44,CEBPG,CRY1,MCL1,MMS19,MSX1,MYC,NPM1,PMAIP1,RAD9A,RINT1,RMI2,RPL26,RPS3,SHLD3,SPRED1,SPRED2,TMEM161A,TPT1,UBE2V2 |
| GO_CELLULAR_GLUCOSE_HOMEOSTASIS | 2.8e-05 | 3.7e-04 | 1603 | 150 | 16 | CDK16,ENY2,FOXA2,GCLC,GCLM,HK2,NADK,NDUFAF2,NME2,NR1D1,PIH1D1,PRKAA1,RAC1,RACK1,SLC9B2,SMARCB1 |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS | 2.8e-05 | 3.7e-04 | 1603 | 134 | 15 | AAAS,AURKA,BCCIP,BORA,CCSAP,CEP97,INTS13,MSTO1,PAFAH1B1,PLK2,PSRC1,SAPCD2,SPRY2,ZNF207,ZW10 |
| GO_RNA_3_END_PROCESSING | 2.8e-05 | 3.7e-04 | 1603 | 150 | 16 | AHCYL1,DDX39A,DHX36,INTS6,MAGOH,RPS21,SRSF1,SRSF3,SRSF7,TENT4B,THOC6,TRNT1,U2AF1,U2AF2,WDR33,ZNF473 |
| GO_RNA_5_END_PROCESSING | 2.8e-05 | 3.7e-04 | 1603 | 20 | 6 | ABT1,NOP14,PIWIL2,RPP30,RPP40,THG1L |
| GO_VESICLE_ORGANIZATION | 2.8e-05 | 3.7e-04 | 1603 | 330 | 26 | ACRBP,ANKRD27,ANXA1,AREG,ARFGAP3,GNAI3,GOLPH3L,GOSR2,LMAN1,MCFD2,PAFAH1B1,PDCD6IP,RAB27A,RFX2,SEC13,SEC23A,SEC24A,SEC24D,SNAP25,SPHK1,STX19,TFG,TGFA,TMED9,TRAPPC6B,VTA1 |
| GO_GERM_CELL_DEVELOPMENT | 2.9e-05 | 3.8e-04 | 1603 | 255 | 22 | ACRBP,AURKA,CCDC36,CIB1,DDX20,EREG,ETV5,FAM9C,MEIOC,PAFAH1B1,PAQR5,PIWIL1,PIWIL2,PLD6,PRDM14,PSME4,RFX2,RNF2,RPS6,RPS6KB1,SMAD5,TAF4B |
| GO_MONOSACCHARIDE_METABOLIC_PROCESS | 2.9e-05 | 3.8e-04 | 1603 | 292 | 24 | ABHD10,ATF3,BPGM,CREM,CRY1,DUSP12,ERFE,FOXA2,FUT2,FUT9,GCLC,HK2,KAT2A,NLN,NR1D1,PFKP,PGAM1,PMAIP1,PMM2,PRKAA1,SELENOS,SERP1,SESN2,SLC35A2 |
| GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | 2.9e-05 | 3.8e-04 | 1603 | 104 | 13 | CCL5,CNOT7,GTF2B,PDE12,POLR2C,POLR2H,POLR2J,PPID,PPIE,RAD23A,SMARCB1,TFAP4,TRIM11 |
| GO_TRANSPOSITION | 2.9e-05 | 3.8e-04 | 1603 | 29 | 7 | APOBEC3A,APOBEC3D,L1TD1,PIWIL1,PIWIL2,THAP10,ZNF91 |
| GO_RESPONSE_TO_ANTIBIOTIC | 3.0e-05 | 3.9e-04 | 1603 | 331 | 26 | ANXA1,AREG,CD14,EIF4EBP1,EZH2,FOSL1,GLRX2,HAMP,HSP90AA1,NET1,PRKAA1,PSMD14,PYCR1,RACK1,RGS4,RPL10A,RPL15,RPL23,RPS3,RPS6KB1,SMPD3,TNC,TRAP1,TUFM,TXN,ZC3H8 |
| GO_CELL_MOTILITY | 3.1e-05 | 4.0e-04 | 1603 | 1758 | 88 | ABI2,ADAMTS1,ADAMTS9,ADGRG3,AIMP1,ANXA1,ANXA5,AP1AR,ARF4,ARHGAP18,ARL13B,ARPC5L,BIN3,C5orf30,CARMIL2,CCL20,CCL5,CCSAP,CD44,CIB1,CKLF,CREB3,CRKL,CXCL2,CXCL3,DOCK5,DUOX2,EMX2,EPHA2,EPPIN,EREG,FGF8,FLT1,FOXC2,GPC6,GTPBP4,HBEGF,HDAC4,HES1,HRH1,IER2,IL23A,INTS13,KARS1,KIRREL3,LDB2,MAP2K1,MAPRE1,MARK2,NAV3,NBL1,NET1,NUS1,OSGIN1,PAFAH1B1,PAK4,PDE4D,PDGFA,PFN2,PLK2,PRDM14,RAC1,RACK1,RFFL,RFX3,RPS19,RPS6KB1,SELENOK,SEMA3A,SGK3,SLC16A1,SLC7A5,SLC7A9,SLC9B2,SLIT2,SMPD3,SMURF2,SPATA13,SPHK1,SPRED1,SPRY2,SRGAP2B,STRIP2,SVBP,TBX20,VAX1,YWHAE,ZNF609 |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 3.1e-05 | 4.1e-04 | 1603 | 710 | 44 | ABCB11,ACBD3,ACOT7,AGPAT5,ALDH8A1,ANXA1,B4GALT3,CDK4,CERS1,CNBP,CSNK2A1,DDX20,DPM1,DPM2,EIF6,FAR1,FDX2,GFI1,GPAT3,HDHD5,HSD17B14,IMPA1,KDSR,LIAS,MFSD2A,NFYA,NR1D1,NR1H2,NUS1,PDGFA,PIGA,PIGL,PLD6,PRKAA1,PRKAB2,RACK1,SELENOI,SMPD3,SPHK1,SPTLC2,ST3GAL4,STARD3NL,TMEM38B,TRIB3 |
| GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY | 3.2e-05 | 4.1e-04 | 1603 | 168 | 17 | BCL10,MAPK9,PSMA4,PSMA5,PSMA6,PSMB1,PSMB3,PSMC5,PSMD11,PSMD13,PSMD14,PSMD3,PSMD4,PSMD7,PSME4,PSMF1,RAC1 |
| GO_GLYCOPROTEIN_METABOLIC_PROCESS | 3.2e-05 | 4.2e-04 | 1603 | 412 | 30 | ADAMTS9,ALG10B,ALG14,B4GALT3,CANT1,DDOST,DPM1,DPM2,DSE,ERP44,FUT2,FUT9,GFPT1,GFPT2,HBEGF,IMPAD1,LMAN1,MCFD2,NGLY1,NUS1,PGM3,PHLDA1,PMM2,RPN1,SEL1L,SERP1,ST3GAL4,SYVN1,TMEM106A,TMEM258 |
| GO_POSITIVE_REGULATION_OF_AUTOPHAGY | 3.2e-05 | 4.2e-04 | 1603 | 120 | 14 | ATG7,C9orf72,CDC37,GNAI3,HK2,MTDH,PIM2,PLK2,PLK3,PRKAA1,RAB3GAP2,SESN2,SPTLC2,TBK1 |
| GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 3.3e-05 | 4.2e-04 | 1603 | 105 | 13 | AAAS,DNAJC27,EMD,IPO5,NOLC1,NUP54,NUP58,RIOK2,TARDBP,TXN,XPO1,XPO5,YWHAE |
| GO_CELL_REDOX_HOMEOSTASIS | 3.4e-05 | 4.4e-04 | 1603 | 77 | 11 | DDIT3,ERP44,GCLC,GLRX2,PDIA3,PDIA6,PRDX4,QSOX1,SELENOS,TXN,TXNDC5 |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 3.4e-05 | 4.3e-04 | 1603 | 353 | 27 | ABCB11,ACOT7,ALDH18A1,ALDH8A1,ANXA1,ASNS,BCAT1,BHMT2,CTH,DSE,EIF6,GPT2,HAAO,LIAS,MTHFD1L,MTR,MTRR,NR1D1,NR1H2,PHGDH,PRKAA1,PRKAB2,PSAT1,PYCR1,SHMT2,SMPD3,TRIB3 |
| GO_OUTER_MITOCHONDRIAL_MEMBRANE_ORGANIZATION | 3.4e-05 | 4.4e-04 | 1603 | 7 | 4 | HSP90AA1,HSPA4,PDCD5,TOMM20 |
| GO_SULFUR_AMINO_ACID_METABOLIC_PROCESS | 3.4e-05 | 4.3e-04 | 1603 | 40 | 8 | BHMT2,BLMH,CTH,GCLC,GCLM,MTR,MTRR,SMS |
| GO_REGULATION_OF_VIRAL_TRANSCRIPTION | 3.5e-05 | 4.5e-04 | 1603 | 64 | 10 | CCL5,GTF2B,POLR2C,POLR2H,POLR2J,SMARCB1,TARDBP,TFAP4,TRIM11,ZFP36 |
| GO_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 3.7e-05 | 4.7e-04 | 1603 | 170 | 17 | BICD1,CNRIP1,EPGN,EREG,IL18BP,MTRNR2L1,MTRNR2L10,MTRNR2L11,MTRNR2L12,MTRNR2L3,MTRNR2L4,MTRNR2L6,MTRNR2L8,NETO1,PATE4,PDE4D,TGFA |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 3.8e-05 | 4.8e-04 | 1603 | 671 | 42 | ACOT7,ADK,AK2,ALG10B,ALG14,B4GALT3,CANT1,DDOST,DPM1,DPM2,DSE,FUT2,FUT9,GFPT1,GFPT2,GNPDA1,GNPDA2,GPC6,HBEGF,LMAN1,MCFD2,MTCO2P12,NANS,NME2,NUS1,PGM3,PHLDA1,PID1,PIGA,PIGL,PMM2,PRKAA1,RPN1,SERP1,SLC35D2,SMPD3,ST3GAL4,SYVN1,TMEM106A,TMEM258,TYW5,UAP1 |
| GO_CARBOHYDRATE_HOMEOSTASIS | 3.8e-05 | 4.8e-04 | 1603 | 241 | 21 | CDK16,CRY1,ENY2,FOXA2,GCLC,GCLM,HK2,NADK,NDUFAF2,NME2,NR1D1,PIH1D1,PRKAA1,RAC1,RACK1,RPS6,SESN2,SLC16A1,SLC9B2,SMARCB1,TENT4B |
| GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 3.8e-05 | 4.8e-04 | 1603 | 278 | 23 | COQ10B,COX10,COX4I1,DLST,GFPT1,GFPT2,IDE,IREB2,MTCO2P12,MTFR1,MYC,NDUFA5,NDUFAF2,NDUFB11,NOP53,NR1D1,PHKG1,PID1,SELENOS,SHMT2,SLC25A14,STK40,TRAP1 |
| GO_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING | 3.9e-05 | 4.9e-04 | 1603 | 21 | 6 | ABT1,BOP1,NOB1,NOP14,RPS21,UTP23 |
| GO_ERYTHROCYTE_HOMEOSTASIS | 3.9e-05 | 4.9e-04 | 1603 | 122 | 14 | ANKRD54,BPGM,CEBPG,IREB2,MFHAS1,PRMT1,RHEX,RPS14,RPS19,RPS24,RPS6,SMAD5,TMOD3,ZFP36 |
| GO_REGULATION_OF_TRANSLATIONAL_FIDELITY | 3.9e-05 | 4.9e-04 | 1603 | 21 | 6 | AARS1,EIF2S3,IARS1,LARS1,RPS5,RPS9 |
| GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE | 4.0e-05 | 5.0e-04 | 1603 | 65 | 10 | COPS5,CXXC1,DNAJB9,FKBP14,GFPT1,GOSR2,PDIA6,SERP1,SRPRA,SYVN1 |
| GO_REGULATION_OF_DNA_REPLICATION | 4.0e-05 | 5.0e-04 | 1603 | 107 | 13 | ATG7,CHTF8,E2F7,EREG,GTPBP4,HUS1,LIG3,NBN,ORC3,PPP2CA,RAC1,TIPIN,ZRANB3 |
| GO_REGULATION_OF_RNA_SPLICING | 4.0e-05 | 5.0e-04 | 1603 | 138 | 15 | AKAP17A,MAGOH,METTL16,NPM1,NUP98,PTBP2,RBM11,RBM19,RPS13,SAP18,SRSF1,SRSF3,SRSF7,TMBIM6,U2AF2 |
| GO_SIGNAL_RELEASE | 4.0e-05 | 5.0e-04 | 1603 | 458 | 32 | ADORA2B,AIMP1,ANXA1,ANXA5,APBA1,BRSK1,CASK,CCL5,CDK16,CRY1,DOC2A,ENY2,FOXA2,ITPR1,NADK,NAPB,NDUFAF2,NIBAN2,NR1D1,PFN2,PPFIA1,RAC1,RAP1B,RFX3,SERP1,SLC16A1,SLC25A6,SLC9B2,SMPD3,SNAP25,STX19,TARDBP |
Num: 7 (Pathways: 155 DK: 11)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (11) | CAMKK1, MAST2, NEK1, NEK4, PAN3, PHKG2, PIP5K1A, TAOK1, TESK1, TLK1, ULK4 |
| Light Kinase (20) | ADPGK, BAZ1A, BAZ1B, CAMK2A, CDK3, CSK, DDR2, DGKE, GRK2, HSPB8, MAP3K6, MAPK7, MLKL, PASK, PI4KB, PIK3C3, SLK, STK4, TPTEP2-CSNK1E, TTN |
| Non-kinase Count | 868 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 1223 | 118 | ACIN1,ALKBH4,ARID2,ARID4B,ASH1L,ASXL1,ATRX,ATXN7,ATXN7L3,BANP,BAZ1A,BAZ1B,BRCC3,BRD8,BRD9,BRPF3,CCNE2,CDK5RAP2,CHAF1B,CHD1,CHD1L,CHD3,CHD6,CHD8,CHMP1A,COPS4,CTCF,DCLRE1A,DEK,DHX9,DQX1,EHMT1,EMSY,EP400,EPC1,EPC2,FBXW7,GINS2,GNL3L,GTF2H1,H2AC12,H2AC7,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,HCFC1,HDAC1,HHEX,HNRNPA2B1,HNRNPD,INO80,ITGB3BP,JMJD1C,KAT6A,KDM2B,KDM3A,KIF4B,KMT2D,KMT2E,M1AP,MBTD1,MCM3,MCM3AP,MCM4,MCM9,MEAF6,MIS18BP1,MPHOSPH8,MSH2,MTA1,MTA2,NAA40,NASP,NIPBL,PCNA,PDS5A,PDS5B,POLD3,PRDM2,PRDM9,RAD51D,RB1,RBL1,RBM14,RCBTB1,RNF168,RNF8,RSF1,SETD1A,SETD2,SETD5,SETD6,SETX,SFPQ,SHPRH,SLF2,SMARCA5,SMARCC1,SMARCE1,SMC2,SMC3,SPDL1,STAG3,STAG3L1,STAG3L3,SUDS3,SUZ12,TET2,TLK1,TTN,USP49,UTY,VPS4B,ZWINT |
| GO_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 795 | 82 | ALKBH4,ARID2,ARID4B,ASH1L,ASXL1,ATRX,ATXN7,ATXN7L3,BANP,BAZ1A,BAZ1B,BRCC3,BRD8,BRD9,BRPF3,CHAF1B,CHD1,CHD1L,CHD3,CHD6,CHD8,CTCF,DEK,EHMT1,EMSY,EP400,EPC1,EPC2,H2AC12,H2AC7,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,HCFC1,HDAC1,INO80,ITGB3BP,JMJD1C,KAT6A,KDM2B,KDM3A,KMT2D,KMT2E,M1AP,MBTD1,MCM3AP,MEAF6,MIS18BP1,MPHOSPH8,MTA1,MTA2,NAA40,NASP,NIPBL,PRDM2,PRDM9,RB1,RBL1,RBM14,RCBTB1,RNF168,RNF8,RSF1,SETD1A,SETD2,SETD5,SETD6,SFPQ,SHPRH,SMARCA5,SMARCC1,SMARCE1,SUDS3,SUZ12,TET2,TLK1,USP49,UTY |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 899 | 1864 | 108 | ACTR1A,ALKBH4,ALMS1,ANKRD17,ATRX,BANP,BBS4,BRCC3,CAB39L,CAMK2A,CASP8AP2,CCNE2,CDK3,CDK5RAP2,CEP295,CHAF1B,CHD3,CHMP1A,CLIP1,CLSPN,CNTLN,CNTRL,CTCF,CUL5,DCLRE1A,E2F1,E2F2,EHMT1,EPB41L2,EPC1,FBXW7,FKBP6,FOXM1,GMNN,GTF2H1,HCFC1,HHEX,HTT,INO80,ITGB3BP,KIF4B,KMT2E,LEP,M1AP,MAEA,MAP4,MAPK7,MCM3,MCM4,MDM2,MIS18BP1,MSH2,NASP,NEK1,NEK4,NIPBL,NUP214,PCNA,PCNT,PDS5A,PDS5B,PIK3C3,POLD3,PPP1R12A,PRDM9,RAD51D,RAD9B,RB1,RBL1,RBM14,RCBTB1,RDX,RNF8,SEPTIN2,SEPTIN7,SETD2,SFPQ,SKA2,SLF2,SMC2,SMC3,SON,SPC24,SPDL1,SPECC1L,STAG3,STAG3L1,STAG3L3,SUZ12,TAOK1,TET2,TLK1,TMEM67,TP53BP1,TP53I13,TP73,TTN,UNC119,URGCP,USP8,VPS4B,WDR76,WHAMM,WHAMMP3,ZFYVE19,ZNF268,ZNF655,ZWINT |
| GO_DNA_CONFORMATION_CHANGE | 0.0e+00 | 0.0e+00 | 899 | 322 | 41 | ACIN1,ASH1L,ATRX,CHAF1B,CHD1,CHD1L,CHD3,CHD6,CHD8,CHMP1A,CTCF,DHX9,DQX1,GINS2,GTF2H1,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,HHEX,HNRNPA2B1,ITGB3BP,KAT6A,M1AP,MCM3,MCM4,MCM9,MIS18BP1,NASP,NIPBL,PRDM9,RNF8,RSF1,SETX,SHPRH,SMARCA5,SMC2,TTN |
| GO_COVALENT_CHROMATIN_MODIFICATION | 0.0e+00 | 0.0e+00 | 899 | 473 | 48 | ARID4B,ASH1L,ASXL1,ATRX,ATXN7,ATXN7L3,BAZ1A,BAZ1B,BRCC3,BRD8,BRPF3,CHD1,CTCF,EHMT1,EP400,EPC1,EPC2,HCFC1,HDAC1,JMJD1C,KAT6A,KDM2B,KDM3A,KMT2D,KMT2E,MCM3AP,MEAF6,MPHOSPH8,MTA1,MTA2,NAA40,NIPBL,PRDM2,PRDM9,RBM14,RNF168,RNF8,RSF1,SETD1A,SETD2,SETD5,SETD6,SFPQ,SUDS3,SUZ12,TET2,USP49,UTY |
| GO_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 899 | 551 | 51 | ANKLE1,ATRX,BOD1L1,BRCC3,CHAF1B,CHD1L,CLSPN,COPS4,DCLRE1A,DEK,DHX9,EMSY,EPC2,FAAP24,FOXM1,FUS,GINS2,GTF2H1,H4C5,INO80,MCM3,MCM4,MCM9,MGME1,MSH2,MTA1,NIPBL,PCNA,PDS5A,PDS5B,PMS2P3,POLD3,POLR2A,PRDM9,RAD51D,RAD52,RAD9B,REV1,RNF111,RNF168,RNF8,SETD2,SETX,SFPQ,SHPRH,SLF2,SMC3,TAOK1,TP53BP1,TP73,UBE2V1 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 899 | 1741 | 93 | ACACA,ACOX3,ACTR1A,ALMS1,ANKFY1,ANKLE1,AP3M1,AP5M1,ATG14,ATP2A2,BBS4,BBS5,BGLAP,BLOC1S3,BLOC1S6,CAPZA1,CCHCR1,CD84,CHMP1A,CLIP1,CPSF1,CTTN,DHX9,DNM1L,DOCK7,EFCAB7,EIF2D,FBXW7,GLE1,GRIPAP1,HHEX,HNRNPA2B1,HOOK3,HPS4,HSPB11,HTT,INPP5F,IPO8,IPO9,KIF1B,KIF5B,KLHL20,LAMP1,LAT,LEP,MALT1,MCM3AP,MDM2,MLPH,NEMF,NF1,NUP214,NXF1,PAN3,PCNT,PEX3,PGAP1,PHAX,PIK3C3,POM121,POM121B,POM121C,PPP1R12A,RAB12,RAB5C,RDX,RGPD8,SETD2,SFPQ,SGSM2,SNX4,SRSF2,SRSF6,SYNRG,TBC1D10B,THOC2,TLK1,TOMM40L,TRAF3IP1,TTC21B,U2AF1L4,VAMP3,VAPB,VPS29,VPS45,VPS4B,VPS50,VPS53,WASHC2A,WHAMM,WHAMMP3,ZC3H11A,ZDHHC9 |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 899 | 856 | 62 | ANKLE1,ATRX,BAZ1B,BCLAF1,BOD1L1,BRCC3,CDK3,CHAF1B,CHD1L,CLSPN,COPS4,DCLRE1A,DEK,DHX9,E2F1,EMSY,EPC2,FAAP24,FOXM1,FUS,GINS2,GTF2H1,H4C5,INO80,MCM3,MCM4,MCM9,MDM2,MGME1,MSH2,MTA1,NCOA6,NEK1,NEK4,NIPBL,PCNA,PDS5A,PDS5B,PMS2P3,POLD3,POLR2A,PRDM9,RAD51D,RAD52,RAD9B,REV1,RNF111,RNF168,RNF8,SETD2,SETX,SFPQ,SHPRH,SLF2,SMC3,TAOK1,TLK1,TOPORS,TP53BP1,TP73,UBE2V1,WDR76 |
| GO_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 925 | 63 | ALKBH4,ANKLE1,ATRX,BOD1L1,BRCC3,CCNE2,CHAF1B,CHD1L,CLSPN,COPS4,CTCF,DCLRE1A,DEK,DHX9,EHMT1,EMSY,EPC2,FAAP24,FKBP6,FOXM1,FUS,GINS2,GNL3L,GTF2H1,H4C5,HNRNPA2B1,HNRNPD,INO80,KMT2E,MCM3,MCM4,MCM9,MGME1,MPHOSPH8,MSH2,MTA1,MTA2,NIPBL,PCNA,PDS5A,PDS5B,PMS2P3,POLD3,POLR2A,PRDM9,RAD51D,RAD52,RAD9B,REV1,RNF111,RNF168,RNF8,SETD2,SETX,SFPQ,SHPRH,SLF2,SMC3,TAOK1,TET2,TP53BP1,TP73,UBE2V1 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 899 | 1930 | 96 | ACOX3,ANKLE1,ANKRD13A,AP3M1,ATRX,BANP,BBS4,C16orf70,CCDC14,CCHCR1,CCNE2,CLIP1,CNTLN,CPLANE1,CPSF1,CSK,CTCF,CTTN,DHX9,DIAPH1,DNM1L,DVL2,DZIP1,E2F1,EFCAB7,EIF2D,EPB41L2,FBXW7,GAS8,GLE1,GNL3L,GRIPAP1,HHEX,HNRNPA2B1,HOOK3,HPS4,HSPB11,INPP5E,IPO8,IPO9,KIF1B,KIF5B,LAMP1,LEP,MCM3AP,MCM9,MDM2,MLPH,MSH2,NECAB2,NF1,NIPBL,NUP214,NXF1,OSBPL8,PAN3,PCNT,PEX3,PIK3C3,PIP5K1A,POM121,POM121B,POM121C,PYGO1,RAB12,RAB5C,RB1,RDX,RGPD8,SETD2,SFPQ,SGSM2,SLF2,SPDL1,SRSF2,SRSF6,SYNRG,SZT2,TAF3,TBC1D10B,THOC2,TLK1,TOMM40L,TOPORS,TOR1AIP1,TP73,TRAF3IP1,TTC21B,TULP3,U2AF1L4,VAMP3,VPS29,VPS45,WASHC2A,ZC3H11A,ZDHHC9 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1870 | 93 | ARID4B,ASH1L,ASXL1,ASXL2,ATRX,ATXN7L3,BANP,BCLAF1,BRCC3,BRD8,CBFB,CCDC62,CDK5RAP2,CHD6,CHD8,CTCF,DHX9,DVL2,E2F1,E2F2,EFCAB7,EPC1,FBXW7,FOXM1,FUS,GTF2H1,HAS3,HCFC1,HDAC1,HHEX,HNRNPA2B1,HNRNPD,HOXA5,INO80,KAT6A,KDM3A,KHSRP,KMT2D,KMT2E,LMO7,MAPK7,MED23,MEF2B,MOV10,MSH2,MTA1,MTA2,NCOA6,NEK4,NFATC2IP,NFYB,NIPBL,PCNA,PIAS2,POLR2A,POU2AF1,POU5F1,PPP1R12A,PRDM2,PRDM9,PRPF6,PYGO1,RB1,RBL1,RBM14,RNF111,RNF168,RNF8,RREB1,RSF1,SEC14L2,SETX,SFPQ,SLF2,SMARCA5,SMARCC1,SMARCE1,SS18,SUPT5H,TBX15,TBX19,TET2,TFCP2,TOPORS,TP53BP1,TP73,TRA2B,UBE2V1,ZBTB20,ZNF175,ZNF268,ZNF292,ZNF746 |
| GO_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1399 | 78 | ACTR1A,ALKBH4,ALMS1,ANKRD17,ATRX,BBS4,BRCC3,CAB39L,CAMK2A,CCNE2,CDK3,CDK5RAP2,CEP295,CHD3,CHMP1A,CLSPN,CNTLN,CNTRL,CTCF,CUL5,E2F1,EHMT1,EPC1,FBXW7,FOXM1,GMNN,HTT,INO80,KIF4B,KMT2E,M1AP,MAP4,MCM3,MCM4,MDM2,MSH2,NASP,NIPBL,PCNA,PCNT,PDS5A,PDS5B,PIK3C3,POLD3,PPP1R12A,PRDM9,RAD51D,RAD9B,RB1,RBL1,RBM14,RDX,SEPTIN2,SEPTIN7,SETD2,SFPQ,SLF2,SMC2,SMC3,SON,SPDL1,STAG3,STAG3L1,STAG3L3,SUZ12,TAOK1,TMEM67,TP73,TTN,UNC119,USP8,VPS4B,WHAMM,WHAMMP3,ZFYVE19,ZNF268,ZNF655,ZWINT |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1988 | 94 | ADM,ARFGEF1,ARID4B,ASH1L,ASXL1,ASXL2,ATRX,ATXN7L3,BANP,BCLAF1,BRD8,CBFB,CCDC62,CDK5RAP2,CHD6,CHD8,CTCF,DHX9,DVL2,E2F1,E2F2,EFCAB7,EIF5AL1,EPC1,FBXW7,FOXM1,FUS,GLMN,GTF2H1,HAS3,HCFC1,HDAC1,HHEX,HNRNPA2B1,HNRNPD,HOXA5,INO80,KAT6A,KDM3A,KMT2D,KMT2E,LARP4,LARP4B,LMO7,MAPK7,MED23,MEF2B,MTA1,MTA2,NCOA6,NEK4,NFATC2IP,NFYB,NIPBL,NSMAF,PASK,PCNA,PIAS2,POU2AF1,POU5F1,PPP1R12A,PPP4R3B,PRDM2,PRDM9,PRPF6,PYGO1,RB1,RBL1,RBM14,RNF111,RREB1,RSF1,SEC14L2,SETX,SFPQ,SMARCA5,SMARCC1,SMARCE1,SS18,SUPT5H,TBX15,TBX19,TET2,TFCP2,TIRAP,TOPORS,TP53BP1,TP73,UBE2V1,UQCC1,ZNF175,ZNF268,ZNF292,ZNF746 |
| GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 287 | 33 | ARID2,ATRX,CHAF1B,CHD1L,CTCF,GMNN,GTF2H1,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,INO80,ITGB3BP,KAT6A,MCM3,MCM3AP,MCM4,MIS18BP1,NASP,PRDM9,RAD52,RB1,RNF8,RSF1,SETD2,SHPRH,SMARCA5,SMARCC1,SMARCE1,TAF1C |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1710 | 85 | ARID4B,ASH1L,ASXL1,ASXL2,ATRX,ATXN7L3,BANP,BCLAF1,BRD8,CBFB,CCDC62,CDK5RAP2,CHD6,CHD8,CTCF,DHX9,DVL2,E2F1,E2F2,EFCAB7,EPC1,FBXW7,FOXM1,FUS,GTF2H1,HAS3,HCFC1,HDAC1,HHEX,HNRNPD,HOXA5,INO80,KAT6A,KDM3A,KHSRP,KMT2D,KMT2E,LMO7,MAPK7,MED23,MEF2B,MOV10,MTA1,MTA2,NCOA6,NEK4,NFATC2IP,NFYB,NIPBL,PIAS2,POLR2A,POU2AF1,POU5F1,PPP1R12A,PRDM2,PRDM9,PRPF6,PYGO1,RB1,RBL1,RBM14,RNF111,RREB1,RSF1,SEC14L2,SETX,SFPQ,SMARCA5,SMARCC1,SMARCE1,SS18,SUPT5H,TBX15,TBX19,TET2,TFCP2,TOPORS,TP53BP1,TP73,TRA2B,UBE2V1,ZNF175,ZNF268,ZNF292,ZNF746 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 899 | 1782 | 86 | ACACA,ADAR,AMFR,AQP11,ARFGEF1,ARHGEF5,ASAP1,ATRX,BBS4,CAMSAP2,CAPZA1,CCDC115,CDK5RAP2,CHAF1B,CHD1L,CLIP1,COIL,CRNKL1,CTTN,DDX23,DHX9,DIAPH1,DNM1L,EIF2D,EIF3A,FCHSD2,FUS,GMNN,GTF2H1,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,HCFC1,HDAC1,HINT3,ITGB3BP,KAT6A,KIRREL1,KMT2D,LUC7L3,LY6G5B,MALT1,MCM3,MCM4,MDM2,MIS18BP1,MLKL,NASP,PIEZO1,PIH1D2,PILRB,PRPF6,PRPF8,PYGO1,RAD52,RB1,RBM5,RDX,RSF1,SCAF11,SDHAF2,SEPTIN7,SETX,SHPRH,SLF2,SMARCA5,SRSF6,SYNJ1,TAF1C,TCAP,TDO2,TP53BP1,TP73,TRA2B,TRAF3IP1,TRPM3,TTN,UQCC1,VAMP3,WASF1,WHAMM,WHAMMP3 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 899 | 1036 | 62 | ADAR,ARFGEF1,ATRX,BBS4,CAMSAP2,CAPZA1,CCDC115,CDK5RAP2,CHAF1B,CHD1L,CLIP1,COIL,CRNKL1,CTTN,DDX23,DHX9,DIAPH1,DNM1L,EIF2D,EIF3A,FCHSD2,GMNN,GTF2H1,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,ITGB3BP,KAT6A,KIRREL1,LUC7L3,MCM3,MCM4,MIS18BP1,NASP,PIH1D2,PILRB,PRPF6,PRPF8,RAD52,RB1,RBM5,RDX,RSF1,SCAF11,SDHAF2,SETX,SHPRH,SMARCA5,SRSF6,SYNJ1,TAF1C,TCAP,TTN,UQCC1,VAMP3,WASF1,WHAMM,WHAMMP3 |
| GO_MRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 899 | 503 | 42 | ACIN1,ADAR,COIL,CPSF1,CRNKL1,DDX23,DDX46,DHX35,DHX40,DHX9,FUS,GTF2H1,HNRNPA1L2,HNRNPA2B1,HNRNPD,HNRNPM,KHSRP,LUC7L3,MFAP1,NCBP3,PAN3,PCF11,POLR2A,PRPF6,PRPF8,RBM5,RNPC3,RPRD2,SCAF11,SETX,SFPQ,SON,SRSF2,SRSF6,SUGP1,SUPT5H,THOC2,TRA2B,U2AF1L4,USP49,WBP4,ZC3H11A |
| GO_PEPTIDYL_LYSINE_MODIFICATION | 0.0e+00 | 0.0e+00 | 899 | 397 | 37 | ARID4B,ASH1L,ATRX,BAZ1A,BRD8,BRPF3,CTCF,EHMT1,EP400,EPC1,EPC2,GNL3L,HCFC1,KAT6A,KDM3A,KMT2D,KMT2E,MCM3AP,MDM2,MEAF6,METTL22,NAA40,NUP214,PIAS2,PLOD3,POM121,POM121C,PRDM2,PRDM9,RSF1,SETD1A,SETD2,SETD5,SETD6,SUZ12,TET2,TOPORS |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 752 | 51 | ACTR1A,ALMS1,AP3M1,ATRX,ATXN7,BBS4,BLOC1S3,BLOC1S6,CAMSAP2,CDK5RAP2,CEP295,CEP350,CHD3,CHMP1A,CLIP1,CNTLN,DIAPH1,DNAH6,DNHD1,DOCK7,GAS8,HOOK3,HSPB11,HTT,INO80,KIF1B,KIF4B,KIF5B,KTN1,LAMP1,MAP4,PCNT,PPP1R12A,RBM14,SETD2,SFPQ,SKA2,SLK,SMC3,SON,SPDL1,SRGAP2,SRGAP2C,SS18,TAOK1,TMEM67,TRAF3IP1,TTC21B,ULK4,VPS4B,WDR73 |
| GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 899 | 191 | 26 | ARID2,ATRX,BAZ1B,CHAF1B,CHD3,CTCF,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,ITGB3BP,KAT6A,M1AP,MIS18BP1,MTA2,NASP,PRDM9,RSF1,SHPRH,SMARCA5,SMARCC1,SMARCE1,TLK1 |
| GO_NUCLEOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 184 | 25 | ARID2,ATRX,CHAF1B,CTCF,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,INO80,ITGB3BP,KAT6A,MCM3AP,MIS18BP1,NASP,PRDM9,RNF8,RSF1,SETD2,SHPRH,SMARCA5,SMARCC1,SMARCE1 |
| GO_DNA_PACKAGING | 0.0e+00 | 0.0e+00 | 899 | 210 | 26 | ACIN1,ASH1L,ATRX,CHAF1B,CHMP1A,CTCF,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,ITGB3BP,KAT6A,M1AP,MIS18BP1,NASP,NIPBL,PRDM9,RNF8,RSF1,SHPRH,SMARCA5,SMC2,TTN |
| GO_ESTABLISHMENT_OF_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 899 | 196 | 25 | CPSF1,DHX9,EIF5AL1,GLE1,HHEX,HNRNPA1L2,HNRNPA2B1,KHSRP,MCM3AP,NCBP3,NPIPA1,NUP214,NXF1,PHAX,POM121,POM121B,POM121C,RFTN2,SETD2,SFPQ,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 899 | 1030 | 58 | ACTR1A,ALMS1,ANKRD17,ATRX,BBS4,CAMK2A,CCNE2,CDK3,CDK5RAP2,CHMP1A,CLIP1,CLSPN,CNTRL,CUL5,E2F1,FOXM1,GMNN,HTT,INO80,KIF4B,KMT2E,MAEA,MAP4,MCM3,MCM4,MDM2,MSH2,NASP,NEK4,NIPBL,NUP214,PCNA,PCNT,PDS5A,PDS5B,PPP1R12A,RAD9B,RB1,RBL1,RDX,SEPTIN7,SETD2,SKA2,SLF2,SMC2,SMC3,SON,SPDL1,TAOK1,TP73,TTN,UNC119,USP8,VPS4B,ZFYVE19,ZNF268,ZNF655,ZWINT |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 899 | 1224 | 64 | ACTR1A,ALMS1,ANKRD17,ATRX,BBS4,BRCC3,CAB39L,CCNE2,CDK3,CDK5RAP2,CEP295,CHMP1A,CLSPN,CNTRL,CTCF,E2F1,E2F2,EHMT1,EPC1,FBXW7,FOXM1,GMNN,GTF2H1,HCFC1,HHEX,INO80,KMT2E,LEP,MAEA,MDM2,MSH2,NIPBL,NUP214,PCNA,PCNT,PIK3C3,PRDM9,RAD51D,RAD9B,RB1,RBL1,RBM14,RDX,SEPTIN7,SETD2,SFPQ,SLF2,SMC3,SON,SPDL1,SUZ12,TAOK1,TMEM67,TP53BP1,TP53I13,TP73,VPS4B,WDR76,WHAMM,WHAMMP3,ZFYVE19,ZNF268,ZNF655,ZWINT |
| GO_MRNA_TRANSPORT | 0.0e+00 | 0.0e+00 | 899 | 151 | 22 | CPSF1,DHX9,EIF5AL1,GLE1,HHEX,HNRNPA1L2,HNRNPA2B1,KHSRP,MCM3AP,NCBP3,NPIPA1,NUP214,NXF1,POM121,POM121B,POM121C,SETD2,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS | 0.0e+00 | 0.0e+00 | 899 | 345 | 32 | COIL,CPSF1,CRNKL1,DDX23,DDX46,DHX35,DHX40,DHX9,FUS,HNRNPA2B1,HNRNPD,HNRNPM,KHSRP,LUC7L3,MFAP1,PCF11,POLR2A,PRPF6,PRPF8,RBM5,RNPC3,SCAF11,SETX,SFPQ,SON,SRSF2,SRSF6,SUGP1,TRA2B,U2AF1L4,USP49,WBP4 |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 1335 | 67 | ACTA1,ACTR1A,ALKBH4,ALMS1,ARFGEF1,ARHGEF5,ATP2C1,ATRX,ATXN7,BBS4,CAMSAP2,CAPZA1,CDK5RAP2,CEP295,CEP350,CHD3,CHMP1A,CLIP1,CNTLN,CNTRL,CTTN,DIAPH1,DOCK7,EPB41L2,FCHSD2,GAS8,HOOK3,HTT,INO80,KIF4B,KIRREL1,KLHL20,LARP4,MAEA,MAP4,MAST2,NF1,PCLO,PCNT,PIP5K1A,PPP1R12A,RBM14,RDX,SETD2,SKA2,SLK,SMC3,SON,SPDL1,SPECC1L,SRGAP2,SRGAP2C,SS18,TAOK1,TCAP,TESK1,TMEM67,TNXB,TRAF3IP1,TTN,ULK4,VPS4B,WASF1,WDR73,WHAMM,WHAMMP3,ZMYM4 |
| GO_CELL_DIVISION | 0.0e+00 | 0.0e+00 | 899 | 598 | 42 | ALKBH4,BBS4,BRCC3,CCNE2,CDK3,CHMP1A,CNTRL,DCLRE1A,DOCK7,EPB41L2,INO80,INTU,ITGB3BP,KIF4B,MAEA,MAP4,MIS18BP1,NEK1,NEK4,NUMBL,PDS5A,PDS5B,PIK3C3,POU5F1,RB1,RBL1,RNF8,SEPTIN2,SEPTIN7,SETD2,SKA2,SMC2,SMC3,SON,SPC24,SPDL1,SPECC1L,UNC119,USP8,VPS4B,ZFYVE19,ZWINT |
| GO_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 899 | 229 | 26 | CPSF1,DHX9,EIF5AL1,GLE1,HHEX,HNRNPA1L2,HNRNPA2B1,KHSRP,MCM3AP,NCBP3,NPIPA1,NUP214,NXF1,PHAX,POM121,POM121B,POM121C,PRPF6,RFTN2,SETD2,SFPQ,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 899 | 944 | 54 | ACOX3,ANKRD13A,AP3M1,ATRX,BANP,BBS4,CCDC14,CNTLN,CPLANE1,CTCF,DHX9,DIAPH1,DNM1L,DZIP1,E2F1,EFCAB7,FBXW7,GAS8,GNL3L,HHEX,HOOK3,HPS4,INPP5E,IPO8,IPO9,LAMP1,LEP,MCM9,MDM2,MSH2,NF1,NIPBL,NUP214,OSBPL8,PEX3,POM121,POM121B,POM121C,PYGO1,RB1,RDX,RGPD8,SETD2,SLF2,SPDL1,SZT2,TAF3,TOMM40L,TOPORS,TOR1AIP1,TP73,TTC21B,TULP3,WASHC2A |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 1267 | 64 | ALKBH4,ALMS1,ARFGEF1,ARHGEF5,ASAP1,ATRX,BBS4,CAMSAP2,CAPZA1,CDK5RAP2,CEP295,CHMP1A,CLIP1,CNTRL,CTCF,CTTN,DIAPH1,DNM1L,DZIP1,E2F1,FBXW7,FCHSD2,GNL3L,HNRNPA2B1,HNRNPD,HPS4,HTT,KDM3A,KIF5B,KIRREL1,KMT2E,LNPK,MAP4,MPHOSPH8,NAA40,NIPBL,ODF2L,PAN3,PRDM9,RB1,RBM14,RDX,SEPTIN7,SETD1A,SETD5,SFPQ,SKA2,SLF2,SMC3,SMCR8,SPDL1,SYNJ1,TAOK1,TESK1,TLK1,TMEM67,TP73,TRAF3IP1,TTC21B,VDAC3,VPS4B,WASF1,WHAMM,WHAMMP3 |
| GO_RNA_SPLICING | 0.0e+00 | 0.0e+00 | 899 | 433 | 35 | ACIN1,COIL,CPSF1,CRNKL1,DDX23,DDX46,DHX35,DHX40,DHX9,FUS,HNRNPA1L2,HNRNPA2B1,HNRNPD,HNRNPM,KHSRP,LUC7L3,MFAP1,PCF11,POLR2A,PRPF6,PRPF8,RBM5,RNPC3,SCAF11,SETX,SFPQ,SON,SRSF2,SRSF6,SUGP1,THOC2,TRA2B,U2AF1L4,USP49,WBP4 |
| GO_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 840 | 50 | ACIN1,ADAR,COIL,CPSF1,CRNKL1,DDX23,DDX46,DDX6,DHX35,DHX40,DHX9,E2F1,EDC4,FUS,GTF2H1,HNRNPA1L2,HNRNPA2B1,HNRNPD,HNRNPM,KHSRP,LUC7L3,MFAP1,MOV10,NCBP3,NUP214,PAN3,PCF11,POLR2A,POU5F1,PRPF6,PRPF8,RBM5,RNPC3,RPRD2,SCAF11,SETX,SFPQ,SON,SRSF2,SRSF6,SUGP1,SUPT5H,TFCP2,THOC2,TIRAP,TRA2B,U2AF1L4,USP49,WBP4,ZC3H11A |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 899 | 1198 | 61 | ARID4B,ASH1L,ASXL1,ASXL2,ATRX,BRD8,CBFB,CCDC62,CHD6,CHD8,CTCF,DHX9,E2F1,E2F2,EFCAB7,EPC1,FBXW7,FOXM1,GTF2H1,HDAC1,HHEX,HOXA5,INO80,KAT6A,KDM3A,KMT2D,LMO7,MAPK7,MEF2B,MTA2,NCOA6,NFATC2IP,NIPBL,POU2AF1,POU5F1,PPP1R12A,PRDM2,PRPF6,PYGO1,RB1,RBL1,RBM14,RNF111,RREB1,RSF1,SETX,SFPQ,SMARCA5,SMARCC1,SS18,SUPT5H,TBX15,TBX19,TET2,TFCP2,TP53BP1,TP73,ZNF175,ZNF268,ZNF292,ZNF746 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1470 | 69 | ATRX,BCLAF1,BTAF1,CASP8AP2,CBFB,CHD8,CHMP1A,CTCF,DHX9,DNAJC17,E2F1,E2F2,EHMT1,EPC1,FOXM1,FUS,GMNN,GNL3L,H3C13,H3C7,H4C5,HCFC1,HDAC1,HHEX,HNRNPA2B1,HNRNPD,KAT6A,KDM2B,KMT2D,LEP,LIMS1,MDM2,MPHOSPH8,MSH2,MTA1,MTA2,NAA40,NIPBL,PCNA,PHF14,POU5F1,QARS1,RB1,RBL1,RNF168,RNF8,RREB1,RSF1,SFPQ,SMARCA5,SMARCE1,SRSF2,SRSF6,SUDS3,SUPT5H,SUZ12,TAF3,TBX15,TBX19,TIRAP,TP53BP1,WWC2,WWP1,ZBTB20,ZGLP1,ZNF12,ZNF175,ZNF268,ZNF746 |
| GO_RNA_PROCESSING | 0.0e+00 | 0.0e+00 | 899 | 917 | 51 | ACIN1,ADAR,COIL,CPSF1,CRNKL1,DDX23,DDX46,DGCR8,DHX35,DHX40,DHX9,FUS,GTF2H1,HNRNPA1L2,HNRNPA2B1,HNRNPD,HNRNPM,KHSRP,LUC7L3,M1AP,MFAP1,NCBP3,PAN3,PCF11,PIH1D2,POLR2A,POP1,PRPF6,PRPF8,RBM5,RNPC3,RPRD2,SCAF11,SETX,SFPQ,SON,SRSF2,SRSF6,SUGP1,SUPT5H,THOC2,TOE1,TRA2B,TRMT2A,TRMT2B,TRMT44,TRMU,U2AF1L4,USP49,WBP4,ZC3H11A |
| GO_NUCLEAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 899 | 347 | 30 | ANKLE1,CCHCR1,CPSF1,DHX9,EFCAB7,GLE1,HHEX,HNRNPA2B1,IPO8,IPO9,LEP,MALT1,MCM3AP,MDM2,NEMF,NF1,NUP214,NXF1,PHAX,POM121,POM121B,POM121C,PPP1R12A,RGPD8,SETD2,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | 0.0e+00 | 0.0e+00 | 899 | 240 | 25 | CPSF1,DHX9,EIF5AL1,GLE1,HHEX,HNRNPA1L2,HNRNPA2B1,KHSRP,MCM3AP,NCBP3,NPIPA1,NUP214,NXF1,PHAX,POM121,POM121B,POM121C,RFTN2,SETD2,SFPQ,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 553 | 38 | ACTR1A,ALMS1,ATRX,ATXN7,BBS4,CAMSAP2,CDK5RAP2,CEP295,CEP350,CHD3,CHMP1A,CLIP1,CNTLN,DOCK7,GAS8,HOOK3,HTT,INO80,KIF4B,MAP4,PCNT,PPP1R12A,RBM14,SETD2,SKA2,SLK,SMC3,SON,SPDL1,SRGAP2,SRGAP2C,SS18,TAOK1,TMEM67,TRAF3IP1,ULK4,VPS4B,WDR73 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 899 | 1258 | 61 | ARID4B,ASH1L,ATRX,BAZ1A,BAZ1B,BRD8,BRPF3,CAMK2A,CLSPN,CNTF,CSK,CTCF,DDR2,DOCK7,DVL2,EHMT1,EP400,EPC1,EPC2,FBXW7,FKBP6,GNL3L,GRK2,HCFC1,IL12RB2,INPP5F,KAT6A,KDM3A,KMT2D,KMT2E,LEP,MAPK7,MAST2,MCM3AP,MDM2,MEAF6,METTL22,NAA40,NEK1,NUP214,PIAS2,PLOD3,POM121,POM121C,PRDM2,PRDM9,RSF1,SETD1A,SETD2,SETD5,SETD6,SH3BP5L,STK4,SUZ12,TESK1,TET2,TLK1,TOPORS,TTN,UNC119,ZDHHC9 |
| GO_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 899 | 189 | 22 | ATRX,CDK5RAP2,CHMP1A,CTCF,FBXW7,INO80,KIF4B,NIPBL,PDS5A,PDS5B,RB1,SFPQ,SLF2,SMC2,SMC3,SPDL1,STAG3,STAG3L1,STAG3L3,TTN,VPS4B,ZWINT |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 899 | 1114 | 56 | AMFR,ASB8,ASXL1,ASXL2,ATXN7,ATXN7L3,BRCC3,CBFB,CLSPN,COPS4,CUL5,DCUN1D1,DNM1L,FBXO17,FBXW12,FBXW7,GLMN,GNL3L,H2BC10,H2BC14,H2BC17,HCFC1,HERC2P3,INO80,KDM2B,KLHL20,LMO7,MAEA,MALT1,MBD5,MDM2,MINAR1,MKRN1,MTA1,NUP214,PCNA,PIAS2,POM121,POM121C,RNF111,RNF144A,RNF168,RNF8,SHPRH,SUDS3,SUZ12,TOPORS,TRIM68,TULP4,UBE2V1,UBR7,UBXN2A,USP49,USP5,USP8,WWP1 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1280 | 61 | ATRX,BCLAF1,BTAF1,CASP8AP2,CBFB,CHD8,CHMP1A,CTCF,DNAJC17,E2F1,E2F2,EHMT1,EPC1,FOXM1,GMNN,H3C13,H3C7,H4C5,HCFC1,HDAC1,HHEX,HNRNPA2B1,KAT6A,KDM2B,KMT2D,LEP,LIMS1,MDM2,MPHOSPH8,MTA1,MTA2,NAA40,NIPBL,PCNA,PHF14,POU5F1,QARS1,RB1,RBL1,RNF168,RNF8,RREB1,RSF1,SFPQ,SMARCA5,SMARCE1,SRSF2,SUDS3,SUPT5H,SUZ12,TAF3,TBX15,TBX19,WWC2,WWP1,ZBTB20,ZGLP1,ZNF12,ZNF175,ZNF268,ZNF746 |
| GO_NUCLEAR_EXPORT | 0.0e+00 | 0.0e+00 | 899 | 195 | 22 | ANKLE1,CCHCR1,CPSF1,DHX9,GLE1,HHEX,HNRNPA2B1,MALT1,MCM3AP,MDM2,NEMF,NUP214,NXF1,PHAX,POM121,POM121C,SETD2,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_NUCLEAR_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 899 | 263 | 25 | ATRX,CCNE2,CDK5RAP2,CHMP1A,CTCF,FBXW7,INO80,KIF4B,M1AP,NIPBL,PDS5A,PDS5B,PRDM9,RB1,SFPQ,SLF2,SMC2,SMC3,SPDL1,STAG3,STAG3L1,STAG3L3,TTN,VPS4B,ZWINT |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 1673 | 71 | ATRX,BCLAF1,BTAF1,CAPRIN1,CASP8AP2,CBFB,CHD8,CHMP1A,CTCF,DNAJC17,E2F1,E2F2,EHMT1,EPC1,FBXW7,FOXM1,GMNN,GNL3L,H3C13,H3C7,H4C5,HCFC1,HDAC1,HHEX,HNRNPA2B1,HNRNPD,KAT6A,KDM2B,KHSRP,KMT2D,LEP,LIMS1,MAEA,MDM2,MOV10,MPHOSPH8,MTA1,MTA2,NAA40,NIPBL,PASK,PCNA,PDS5A,PHF14,POU5F1,QARS1,RB1,RBL1,RNF168,RNF8,RREB1,RSF1,SFPQ,SMARCA5,SMARCE1,SRSF2,SUDS3,SUPT5H,SUZ12,TAF3,TBX15,TBX19,TTF1,WWC2,WWP1,ZBTB20,ZGLP1,ZNF12,ZNF175,ZNF268,ZNF746 |
| GO_DOUBLE_STRAND_BREAK_REPAIR | 0.0e+00 | 0.0e+00 | 899 | 251 | 24 | BRCC3,DCLRE1A,DEK,FOXM1,FUS,GINS2,H4C5,INO80,MCM3,MCM4,MCM9,MSH2,MTA1,NIPBL,PRDM9,RAD51D,RAD52,RNF168,RNF8,SETD2,SETX,SFPQ,SLF2,TP53BP1 |
| GO_CHROMATIN_REMODELING | 0.0e+00 | 0.0e+00 | 899 | 172 | 20 | ATRX,BAZ1A,BAZ1B,CHD1,CHD1L,CHD3,CHD8,H4C5,HDAC1,INO80,ITGB3BP,MIS18BP1,MTA2,NASP,RB1,RNF8,RSF1,SMARCA5,SMARCC1,SMARCE1 |
| GO_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 899 | 324 | 27 | ATRX,CCNE2,CDK5RAP2,CHMP1A,CTCF,FBXW7,INO80,KIF4B,M1AP,NIPBL,PDS5A,PDS5B,PRDM9,RB1,SFPQ,SKA2,SLF2,SMC2,SMC3,SPDL1,STAG3,STAG3L1,STAG3L3,TLK1,TTN,VPS4B,ZWINT |
| GO_SISTER_CHROMATID_COHESION | 0.0e+00 | 0.0e+00 | 899 | 63 | 13 | ATRX,CTCF,FBXW7,NIPBL,PDS5A,PDS5B,RB1,SFPQ,SLF2,SMC3,STAG3,STAG3L1,STAG3L3 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 1220 | 57 | ANKFY1,ARHGEF5,ASAP1,ATRX,BBS4,CAPRIN1,CDK5RAP2,CEP295,CHD1L,CLIP1,CNTF,CPNE9,CTTN,DDR2,DEF8,DNM1L,DVL2,DZIP1,E2F1,EIF5AL1,EPS8L3,FBXW7,FCHSD2,GTF2H1,HAS3,HNRNPA2B1,HNRNPD,HPS4,HTT,KIF5B,KIRREL1,KMT2E,LIMS1,LNPK,MPHOSPH8,NIPBL,PAN3,PIEZO1,PPT1,PRDM9,RB1,RREB1,SEPTIN7,SETX,SFPQ,SHOX2,SLF2,SMCR8,SYNJ1,TESK1,TP73,VPS4B,WASF1,WHAMM,WHAMMP3,WNT3,ZNF804A |
| GO_CHROMATIN_ASSEMBLY | 0.0e+00 | 0.0e+00 | 899 | 165 | 19 | ATRX,CHAF1B,CTCF,H2BC10,H2BC14,H2BC17,H2BC18,H3C13,H3C7,H4C5,ITGB3BP,KAT6A,M1AP,MIS18BP1,NASP,PRDM9,RSF1,SHPRH,SMARCA5 |
| GO_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 899 | 790 | 43 | ACTR1A,ALMS1,ANKRD17,ATRX,BBS4,BRCC3,CDK5RAP2,CEP295,CHMP1A,CLSPN,CNTRL,CTCF,E2F1,EHMT1,EPC1,FBXW7,FOXM1,INO80,KMT2E,MDM2,NIPBL,PCNA,PCNT,PIK3C3,PRDM9,RB1,RBL1,RBM14,RDX,SEPTIN7,SETD2,SFPQ,SLF2,SMC3,SPDL1,SUZ12,TAOK1,TMEM67,TP73,VPS4B,ZFYVE19,ZNF268,ZNF655 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 899 | 1545 | 65 | ACTR1A,ADM,ALMS1,ARFGEF1,ASAP1,BBS4,BBS5,BLOC1S3,BLOC1S6,CAMK2A,CAMSAP2,CAPRIN1,CDK5RAP2,CNTF,CNTRL,CPLANE1,CPNE9,CTTN,DEF8,DNM1L,DOCK10,DOCK7,DVL2,DZIP1,EPS8L3,FAM92A,FRS2,GAS8,HSPB11,HTT,INPP5F,INTU,KIF5B,MAP4,MAPK7,MDM2,MINAR1,MOV10,NEK1,NUMBL,ODF2L,PCNT,PIP5K1A,PLCG1,PSPN,QRICH2,RB1,RDX,RREB1,SEPTIN2,SEPTIN7,SETX,SHOX2,SRGAP2,SRGAP2C,STK4,SZT2,TMEM67,TRAF3IP1,TTC21B,ULK4,VDAC3,WHAMM,WNT3,ZNF804A |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 1.0e-07 | 899 | 624 | 37 | ARHGEF5,ASAP1,ATRX,BBS4,CDK5RAP2,CEP295,CLIP1,CTTN,DNM1L,DZIP1,E2F1,FBXW7,FCHSD2,HNRNPA2B1,HNRNPD,HPS4,HTT,KIF5B,KIRREL1,KMT2E,LNPK,MPHOSPH8,NIPBL,PAN3,PRDM9,RB1,SEPTIN7,SFPQ,SLF2,SMCR8,SYNJ1,TESK1,TP73,VPS4B,WASF1,WHAMM,WHAMMP3 |
| GO_RNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 1.0e-07 | 899 | 136 | 17 | CPSF1,DHX9,GLE1,HHEX,HNRNPA2B1,MCM3AP,NUP214,NXF1,PHAX,POM121,POM121C,SETD2,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_ATP_DEPENDENT_CHROMATIN_REMODELING | 0.0e+00 | 1.0e-07 | 899 | 89 | 14 | CHD3,CHD8,H4C5,HDAC1,INO80,ITGB3BP,MIS18BP1,MTA2,NASP,RNF8,RSF1,SMARCA5,SMARCC1,SMARCE1 |
| GO_DNA_REPLICATION | 0.0e+00 | 1.0e-07 | 899 | 267 | 23 | ANKRD17,ATRX,BAZ1A,BOD1L1,CCNE2,CHAF1B,CLSPN,DHX9,GINS2,GMNN,INO80,MCM3,MCM4,MCM9,MGME1,NASP,PCNA,PDS5A,POLD3,RAD9B,REV1,SMC3,TTF1 |
| GO_ORGANELLE_ASSEMBLY | 0.0e+00 | 1.0e-07 | 899 | 835 | 43 | ACTA1,ACTR1A,ALMS1,ARHGEF5,ASAP1,ATG14,BBS4,BBS5,CDK5RAP2,CEP295,CHMP1A,CNTRL,CPLANE1,DDX6,DZIP1,FAM92A,GAS8,HPS4,HSPB11,HTT,INO80,INTU,KIF4B,MAP4,NEK1,ODF2L,PAN3,PCNT,PIK3C3,RBM14,RDX,SEPTIN2,SEPTIN7,SMC3,SMCR8,TCAP,TMEM67,TRAF3IP1,TTC21B,TTN,UBXN2A,VDAC3,VPS4B |
| GO_MRNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 2.0e-07 | 899 | 111 | 15 | CPSF1,GLE1,HHEX,HNRNPA2B1,MCM3AP,NUP214,NXF1,POM121,POM121C,SETD2,SRSF2,SRSF6,THOC2,U2AF1L4,ZC3H11A |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 2.0e-07 | 899 | 942 | 46 | ALMS1,ARFGEF1,ARHGEF5,ASAP1,BBS4,CAMSAP2,CAPZA1,CBFB,CDK5RAP2,CEP295,CHD1L,CHMP1A,CLIP1,CTTN,DEF8,DNM1L,DZIP1,EPS8L3,FCHSD2,GTF2H1,HAS3,HCFC1,HTT,KIRREL1,LIMS1,MAP4,NSMAF,ODF2L,PAN3,PIEZO1,RB1,RBM14,RDX,SEPTIN7,SLF2,SLK,SMC3,SMCR8,SRGAP2C,TESK1,TRAF3IP1,VDAC3,VPS4B,WASF1,WHAMM,WHAMMP3 |
| GO_PEPTIDYL_LYSINE_METHYLATION | 0.0e+00 | 2.0e-07 | 899 | 130 | 16 | ARID4B,ASH1L,ATRX,EHMT1,KDM3A,KMT2D,KMT2E,METTL22,PRDM2,PRDM9,SETD1A,SETD2,SETD5,SETD6,SUZ12,TET2 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 2.0e-07 | 899 | 1151 | 52 | ACOX3,ANKLE1,AP3M1,CCHCR1,CLIP1,CPSF1,CTTN,EFCAB7,EIF2D,FBXW7,GLE1,GRIPAP1,HHEX,HNRNPA2B1,HPS4,HSPB11,IPO8,IPO9,KIF5B,LEP,MCM3AP,MDM2,MLPH,NF1,NUP214,NXF1,PAN3,PCNT,PEX3,POM121,POM121B,POM121C,RAB12,RAB5C,RGPD8,SETD2,SFPQ,SGSM2,SRSF2,SRSF6,SYNRG,TBC1D10B,THOC2,TLK1,TOMM40L,TRAF3IP1,TTC21B,U2AF1L4,VPS29,VPS45,ZC3H11A,ZDHHC9 |
| GO_DNA_GEOMETRIC_CHANGE | 0.0e+00 | 3.0e-07 | 899 | 114 | 15 | ATRX,CHD1,CHD1L,CHD3,CHD6,CHD8,DHX9,DQX1,GINS2,GTF2H1,HNRNPA2B1,MCM3,MCM4,MCM9,SETX |
| GO_MACROMOLECULE_METHYLATION | 0.0e+00 | 3.0e-07 | 899 | 306 | 24 | ARID4B,ASH1L,ATRX,CTCF,EHMT1,FKBP6,KDM3A,KMT2D,KMT2E,METTL11B,METTL22,MPHOSPH8,MTA2,PRDM2,PRDM9,SETD1A,SETD2,SETD5,SETD6,SUZ12,TET2,TRMT2A,TRMT2B,TRMT44 |
| GO_REGULATION_OF_ORGANELLE_ASSEMBLY | 0.0e+00 | 3.0e-07 | 899 | 194 | 19 | ALMS1,ARHGEF5,ASAP1,BBS4,CDK5RAP2,CEP295,CHMP1A,DZIP1,HTT,MAP4,ODF2L,PAN3,RBM14,RDX,SEPTIN7,SMC3,SMCR8,VDAC3,VPS4B |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 3.0e-07 | 899 | 995 | 47 | ASPA,ATRX,BBS4,CCDC14,CDK5RAP2,CHD8,CNTF,CPLANE1,CSK,CTNND1,DOCK7,E2F1,FRS2,GAS8,HDAC1,HNRNPD,HOOK3,INTU,KDM2B,KIF5B,LEP,MACO1,MBOAT7,NCOA6,NF1,NIPBL,NUMBL,PGAP1,PHLPP2,PPT1,PSPN,QARS1,SETD2,SRGAP2,SRGAP2C,STK4,SUDS3,SYNJ1,SZT2,TBX19,TP73,TRA2B,TTC21B,TULP3,VCX3A,WNT3,WWP1 |
| GO_HEAD_DEVELOPMENT | 0.0e+00 | 4.0e-07 | 899 | 774 | 40 | ATRX,BBS4,CCDC14,CDK5RAP2,CHD8,CPLANE1,CSK,CTNND1,DOCK7,E2F1,FLVCR1,FRS2,GAS8,HDAC1,HNRNPD,HOOK3,KDM2B,KIF5B,MACO1,MBOAT7,NCOA6,NF1,NIPBL,NUMBL,PGAP1,PHLPP2,PPT1,QARS1,SETD2,SRGAP2,SRGAP2C,SUDS3,SYNJ1,SZT2,TBX19,TRA2B,TTC21B,TULP3,VCX3A,WNT3 |
| GO_HISTONE_METHYLATION | 0.0e+00 | 5.0e-07 | 899 | 138 | 16 | ARID4B,ASH1L,ATRX,CTCF,EHMT1,KDM3A,KMT2D,KMT2E,PRDM2,PRDM9,SETD1A,SETD2,SETD5,SETD6,SUZ12,TET2 |
| GO_PROTEIN_METHYLATION | 0.0e+00 | 5.0e-07 | 899 | 178 | 18 | ARID4B,ASH1L,ATRX,CTCF,EHMT1,KDM3A,KMT2D,KMT2E,METTL11B,METTL22,PRDM2,PRDM9,SETD1A,SETD2,SETD5,SETD6,SUZ12,TET2 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 5.0e-07 | 899 | 1880 | 71 | ADAR,AKT1S1,ARFGEF1,ARHGEF5,ASH1L,ATG14,ATRX,BOD1L1,CAMKK1,CCNE2,CEP295,CLSPN,CNTF,CSK,CTCF,DCUN1D1,DDR2,DNM1L,DOCK7,DVL2,EIF3A,FBXW7,FOXM1,FRS2,GLMN,GNL3L,GTF2H1,HHEX,HTT,INPP5F,KDM3A,KIRREL1,KMT2E,LAT,LEP,MALT1,MAP3K6,MINAR1,MOB1B,MTA1,NECAB2,NEK1,NEK4,NF1,NIPBL,OSBPL8,PARP16,PILRB,PPP1R12A,PPP1R7,PPP2R5C,PRDM9,QARS1,RB1,RNF111,SETD5,SH3BP5L,SLK,SMCR8,STK4,TAOK1,TESK1,TIRAP,TOPORS,TP73,TRAF3IP1,TTN,UBE2V1,UBXN2A,ULK4,UNC119 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 5.0e-07 | 899 | 912 | 44 | AMFR,ASB8,ATXN7L3,CBFB,CUL5,DCUN1D1,DNM1L,FBXO17,FBXW12,FBXW7,GLMN,GNL3L,H2BC10,H2BC14,H2BC17,HERC2P3,KDM2B,KLHL20,LMO7,MAEA,MALT1,MDM2,MINAR1,MKRN1,MTA1,NUP214,PCNA,PIAS2,POM121,POM121C,RNF111,RNF144A,RNF168,RNF8,SHPRH,SUZ12,TOPORS,TRIM68,TULP4,UBE2V1,UBR7,UBXN2A,USP5,WWP1 |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 5.0e-07 | 899 | 567 | 33 | ACTR1A,ALMS1,ASAP1,BBS4,BBS5,CDK5RAP2,CNTRL,CPLANE1,CTTN,DEF8,DZIP1,EPS8L3,FAM92A,GAS8,HSPB11,HTT,INTU,MAP4,NEK1,ODF2L,PCNT,PIP5K1A,QRICH2,RDX,SEPTIN2,SEPTIN7,SRGAP2,SRGAP2C,TMEM67,TRAF3IP1,TTC21B,VDAC3,WHAMM |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 5.0e-07 | 899 | 751 | 39 | AKT1S1,ANKLE1,ARHGEF5,BCLAF1,BRCC3,CAMK2A,CNTF,DEK,DHX9,DVL2,FBXW7,FOXM1,FUS,HSPB8,INPP5F,LEP,MAP3K6,MAPK7,MDM2,NEK4,NUP214,PCNA,POM121,POM121C,QARS1,RAD52,RBL1,RNF168,RNF8,SETD2,SFPQ,SLF2,SZT2,TAOK1,TIRAP,TP53BP1,UBE2V1,ULK4,WDR76 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 7.0e-07 | 899 | 1781 | 68 | AGAP5,AMFR,AMH,ARFGEF1,ARHGEF5,ASAP1,ATG14,CAMK2A,CAMKK1,CASP8AP2,CLSPN,CSK,DCUN1D1,DDR2,DHX9,DNAJB4,DNM1L,DOCK10,DOCK7,DVL2,ELMOD3,FAM13B,FBXW7,FRS2,GAPVD1,GMNN,GNL3L,HNRNPA2B1,HNRNPD,HTT,KIF5B,LAT,LEP,LIMS1,MALT1,MAP3K6,MOB1B,MSH2,NEK1,NEK4,NF1,NIPBL,NSMAF,OSBPL8,PARP16,PCNA,PILRB,PIP5K1A,PLCG1,PPP1R12A,RALBP1,RALGAPA1,RB1,RGPD8,RIC8A,SGSM2,SLK,SRGAP2,STK4,TAOK1,TBC1D10B,TIRAP,TOPORS,TOR1AIP1,TP53BP1,TP73,UBE2V1,UNC119 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 8.0e-07 | 899 | 637 | 35 | ATRX,BRCC3,CAB39L,CDK5RAP2,CHMP1A,CLSPN,E2F1,EHMT1,EPC1,FOXM1,GMNN,HHEX,KMT2E,MDM2,MSH2,PCNA,RAD9B,RB1,RBL1,RBM14,SEPTIN7,SPDL1,SUZ12,TAOK1,TMEM67,TP53BP1,TP53I13,TP73,WDR76,WHAMM,WHAMMP3,ZFYVE19,ZNF268,ZNF655,ZWINT |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 1.1e-06 | 899 | 1429 | 58 | AGAP5,ARFGEF1,ARHGEF5,ASAP1,ATG14,CAMKK1,CASP8AP2,CLSPN,CSK,DCUN1D1,DDR2,DHX9,DNAJB4,DNM1L,DOCK10,DOCK7,DVL2,ELMOD3,FAM13B,FBXW7,FRS2,GAPVD1,HNRNPA2B1,HNRNPD,LAT,LEP,LIMS1,MALT1,MAP3K6,MOB1B,MSH2,NEK1,NEK4,NF1,NSMAF,OSBPL8,PARP16,PCNA,PILRB,PIP5K1A,PLCG1,PPP1R12A,RALBP1,RALGAPA1,RGPD8,RIC8A,SGSM2,SLK,SRGAP2,STK4,TAOK1,TBC1D10B,TIRAP,TOPORS,TOR1AIP1,TP73,UBE2V1,UNC119 |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 1.2e-06 | 899 | 940 | 44 | ADAR,ANKRD17,AP3M1,CD46,CHD1,CHD6,CHMP1A,CTNND1,CUL5,DDX6,DEK,DHX9,EIF2D,EIF3A,EXOC7,FBXW7,FKBP6,FUCA2,GRK2,GYPA,HCFC1,HDAC1,LAMP1,MDM2,MPHOSPH8,NUP214,NXF1,PCNA,PILRA,PLCG1,POLR2A,POM121,POM121C,RB1,RBL1,RSF1,STAU1,SUPT5H,THOC2,TP73,VAPB,VPS29,VPS4B,WWP1 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 1.3e-06 | 899 | 976 | 45 | ADAR,AKT1S1,ARHGEF5,ATG14,CAMKK1,CCNE2,CLSPN,CSK,DCUN1D1,DDR2,DNM1L,DVL2,FBXW7,FRS2,GTF2H1,HHEX,HNRNPA2B1,HNRNPD,HTT,LAT,LEP,MALT1,MAP3K6,MOB1B,NEK1,NEK4,NF1,OSBPL8,PARP16,PILRB,QARS1,RB1,RBL1,SH3BP5L,SLK,SMCR8,STK4,TAOK1,TESK1,TIRAP,TOPORS,TP73,TTN,UBE2V1,UNC119 |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 1.4e-06 | 899 | 622 | 34 | ACTR1A,ALMS1,AP3M1,ATG14,BBS4,BBS5,BLOC1S3,BLOC1S6,CD84,CDK5RAP2,CHMP1A,CNTRL,DEF8,DNM1L,DOCK7,HOOK3,HTT,KIF1B,KIF5B,LAMP1,LAT,MAP4,MLPH,PCLO,PCNT,RAB12,SNX4,SPDL1,SYNJ1,TMEM67,VAMP3,VAPB,VPS45,VPS4B |
| GO_METHYLATION | 0.0e+00 | 1.6e-06 | 899 | 366 | 25 | ARID4B,ASH1L,ATRX,CTCF,EHMT1,FKBP6,KDM3A,KMT2D,KMT2E,METTL11B,METTL22,MPHOSPH8,MTA2,PRDM10,PRDM2,PRDM9,SETD1A,SETD2,SETD5,SETD6,SUZ12,TET2,TRMT2A,TRMT2B,TRMT44 |
| GO_GAMETE_GENERATION | 0.0e+00 | 2.2e-06 | 899 | 698 | 36 | ACTR1A,AFF4,AMH,ARID4B,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,DDX6,DZIP1,E2F1,FKBP6,HSPB11,KDM2B,KDM3A,KMT2D,LEP,M1AP,MAST2,MCM9,MEA1,MSH2,PMFBP1,PRDM9,PYGO1,RNF8,SEPTIN2,SEPTIN7,SETX,TDRD6,TESK1,WNT3,ZGLP1,ZNF35 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 2.2e-06 | 899 | 860 | 41 | ATRX,CBFB,CHD8,CTCF,DNAJC17,E2F1,E2F2,EHMT1,EPC1,FOXM1,HCFC1,HDAC1,HHEX,HNRNPA2B1,KDM2B,LEP,MDM2,MTA1,MTA2,NIPBL,PCNA,PHF14,POU5F1,RB1,RBL1,RNF168,RNF8,RREB1,SFPQ,SUDS3,SUPT5H,SUZ12,TAF3,TBX15,TBX19,WWC2,ZBTB20,ZGLP1,ZNF175,ZNF268,ZNF746 |
| GO_SEXUAL_REPRODUCTION | 0.0e+00 | 4.1e-06 | 899 | 847 | 40 | ACTR1A,ADAM20,AFF4,AMH,ARID4B,ASH1L,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,CD46,DDX6,DZIP1,E2F1,FKBP6,HSPB11,KDM2B,KDM3A,KMT2D,LEP,M1AP,MAST2,MCM9,MEA1,MSH2,PMFBP1,PRDM9,PYGO1,RNF8,SEPTIN2,SEPTIN7,SETX,SPACA6,TDRD6,TESK1,WNT3,ZGLP1,ZNF35 |
| GO_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | 1.0e-07 | 6.2e-06 | 899 | 286 | 21 | CPSF1,GLE1,GRIPAP1,HHEX,HNRNPA2B1,HSPB11,KIF5B,MCM3AP,NUP214,NXF1,POM121,POM121C,SETD2,SFPQ,SRSF2,SRSF6,THOC2,TRAF3IP1,TTC21B,U2AF1L4,ZC3H11A |
| GO_CELL_CYCLE_PHASE_TRANSITION | 1.0e-07 | 7.4e-06 | 899 | 637 | 33 | ACTR1A,ALMS1,ANKRD17,BRCC3,CAMK2A,CCNE2,CDK3,CDK5RAP2,CLSPN,CNTRL,CUL5,E2F1,FBXW7,FOXM1,GMNN,INO80,KMT2E,MCM3,MCM4,MDM2,NASP,PCNA,PCNT,PPP1R12A,RB1,RBL1,RDX,SEPTIN7,SPDL1,TAOK1,VPS4B,ZFYVE19,ZNF655 |
| GO_REGULATION_OF_KINASE_ACTIVITY | 1.0e-07 | 8.4e-06 | 899 | 872 | 40 | ADAR,AKT1S1,ARHGEF5,ATG14,CAMKK1,CCNE2,CLSPN,CSK,DDR2,DVL2,FBXW7,FRS2,GTF2H1,HHEX,HTT,LAT,LEP,MALT1,MAP3K6,MOB1B,NEK1,NEK4,NF1,OSBPL8,PARP16,PILRB,QARS1,RB1,RBL1,SH3BP5L,SLK,SMCR8,STK4,TAOK1,TESK1,TIRAP,TP73,TTN,UBE2V1,UNC119 |
| GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 1.0e-07 | 8.4e-06 | 899 | 217 | 18 | ANKLE1,BCLAF1,BRCC3,DEK,DHX9,FOXM1,FUS,MDM2,NEK4,PCNA,RAD52,RNF168,RNF8,SETD2,SLF2,TP53BP1,UBE2V1,WDR76 |
| GO_MITOTIC_SISTER_CHROMATID_SEGREGATION | 1.0e-07 | 9.2e-06 | 899 | 151 | 15 | ATRX,CDK5RAP2,CHMP1A,INO80,KIF4B,NIPBL,PDS5A,PDS5B,RB1,SLF2,SMC2,SPDL1,TTN,VPS4B,ZWINT |
| GO_CILIUM_ORGANIZATION | 2.0e-07 | 1.3e-05 | 899 | 381 | 24 | ACTR1A,ALMS1,ASAP1,BBS4,BBS5,CDK5RAP2,CNTRL,CPLANE1,DZIP1,FAM92A,GAS8,HSPB11,HTT,INTU,MAP4,NEK1,ODF2L,PCNT,SEPTIN2,SEPTIN7,TMEM67,TRAF3IP1,TTC21B,VDAC3 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 2.0e-07 | 1.3e-05 | 899 | 853 | 39 | ACTR1A,AFF4,AMH,ARID4B,ASH1L,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,DDX6,DZIP1,E2F1,FKBP6,HSPB11,KDM2B,KDM3A,KMT2D,LEP,M1AP,MAST2,MCM9,MEA1,MSH2,PCNA,PMFBP1,PRDM9,PYGO1,RNF8,SEPTIN2,SEPTIN7,SETX,SPACA6,TDRD6,TESK1,WNT3,ZGLP1,ZNF35 |
| GO_EMBRYO_DEVELOPMENT | 2.0e-07 | 1.3e-05 | 899 | 1029 | 44 | ADM,ARID2,BBS4,BBS5,CCDC62,CHD8,CPLANE1,DHX35,DVL2,EHMT1,FLVCR1,FRS2,GLMN,HCFC1,HDAC1,HOXA5,INTU,KDM2B,KIAA1217,LNPK,LRIG3,MAPK7,MBTD1,MSH2,NASP,NF1,NIPBL,PGAP1,PLCG1,PLOD3,POU5F1,RIC8A,SEPTIN7,SETD2,SHOX2,SMPD4,STK4,TBX15,TBX19,TCAP,TRA2B,TRAF3IP1,TULP3,WNT3 |
| GO_MALE_GAMETE_GENERATION | 2.0e-07 | 1.4e-05 | 899 | 562 | 30 | ACTR1A,AFF4,ARID4B,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,DDX6,DZIP1,E2F1,FKBP6,HSPB11,KDM2B,KDM3A,M1AP,MAST2,MEA1,PMFBP1,PRDM9,PYGO1,RNF8,SEPTIN2,SEPTIN7,SETX,TDRD6,TESK1,ZGLP1,ZNF35 |
| GO_REPRODUCTION | 3.0e-07 | 2.2e-05 | 899 | 1457 | 55 | ACTR1A,ADAM20,ADM,AFF4,AMH,ARID4B,ASH1L,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,CCNE2,CD46,DDX6,DZIP1,E2F1,FKBP6,FRS2,GAS8,HSPB11,KDM2B,KDM3A,KMT2D,LEP,M1AP,MAST2,MCM9,MEA1,MSH2,NASP,NIPBL,PCNA,PMFBP1,PRDM9,PYGO1,QRICH2,RAD51D,RNF8,SEPTIN2,SEPTIN7,SETD2,SETX,SMARCC1,SMC2,SMC3,SPACA6,STAG3,STK4,TDRD6,TESK1,WNT3,ZGLP1,ZNF35 |
| GO_REGULATION_OF_DNA_REPAIR | 3.0e-07 | 2.7e-05 | 899 | 122 | 13 | BRCC3,DEK,DHX9,FOXM1,FUS,PCNA,RAD52,RNF168,RNF8,SETD2,SLF2,TP53BP1,UBE2V1 |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | 5.0e-07 | 3.5e-05 | 899 | 266 | 19 | BANP,BBS4,EFCAB7,HHEX,IPO8,IPO9,LEP,MDM2,NF1,NUP214,OSBPL8,POM121,POM121B,POM121C,PYGO1,RGPD8,TAF3,TOPORS,TOR1AIP1 |
| GO_PROTEIN_PHOSPHORYLATION | 5.0e-07 | 3.6e-05 | 899 | 1994 | 68 | ADAR,AKT1S1,ARHGEF5,ASH1L,ATG14,BAZ1B,CAB39L,CAMK2A,CAMKK1,CCNE2,CDK3,CLSPN,CNTF,CSK,DDR2,DOCK7,DVL2,EIF3A,FBXW7,FOXM1,FRS2,GRK2,GTF2H1,HHEX,HSPB8,HTT,IL12RB2,INPP5F,KIRREL1,LAT,LEP,MALT1,MAP3K6,MAPK7,MAST2,MLKL,MOB1B,NECAB2,NEK1,NEK4,NF1,OSBPL8,PAN3,PARP16,PASK,PHKG2,PIK3C3,PILRB,PPP2R5C,PSPN,QARS1,RASGRF2,RB1,SETX,SH3BP5L,SLK,SMCR8,STK4,TAOK1,TESK1,TIRAP,TLK1,TP73,TRAF3IP1,TTN,UBE2V1,ULK4,UNC119 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 5.0e-07 | 3.6e-05 | 899 | 1559 | 57 | ADAR,AKT1S1,ANKLE1,ANKRD17,ARFGEF1,ARHGEF5,ASH1L,BCLAF1,BRCC3,CAMK2A,CNTF,DEK,DHX9,DVL2,FBXW7,FOXM1,FUS,HSPB8,IL17RB,INPP5F,LAMP1,LEP,MALT1,MAP3K6,MAPK7,MAPKBP1,MDM2,MUC5AC,NEK4,NUP214,PCNA,PIK3C3,POM121,POM121C,QARS1,RAD52,RB1,RBL1,RBM14,RNF168,RNF8,RREB1,SETD2,SETD6,SFPQ,SLF2,SNX4,SRSF6,SZT2,TAOK1,TIRAP,TP53BP1,TRAF3IP1,UBE2V1,ULK4,WDR76,ZBP1 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | 5.0e-07 | 3.8e-05 | 899 | 193 | 16 | ADAR,COIL,CRNKL1,DDX23,DHX9,EIF2D,EIF3A,KIF5B,LUC7L3,PIH1D2,PRPF6,PRPF8,RBM5,SCAF11,SETX,SRSF6 |
| GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 6.0e-07 | 4.5e-05 | 899 | 220 | 17 | ALMS1,BBS4,CAMSAP2,CDK5RAP2,CEP295,CHMP1A,CLIP1,DIAPH1,LAMP1,RBM14,SKA2,SMC3,TAOK1,TMEM67,TRAF3IP1,TTC21B,VPS4B |
| GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | 6.0e-07 | 4.7e-05 | 899 | 299 | 20 | ANKRD17,CAMK2A,CCNE2,CDK3,CUL5,E2F1,FBXW7,GMNN,INO80,KMT2E,MCM3,MCM4,MDM2,NASP,PCNA,RB1,RBL1,RDX,SEPTIN7,ZNF655 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 6.0e-07 | 4.7e-05 | 899 | 974 | 41 | ACTR1A,ADM,AFF4,AMH,ARID4B,ASH1L,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,DDX6,DZIP1,E2F1,FKBP6,FRS2,HSPB11,KDM2B,KDM3A,KMT2D,LEP,M1AP,MAST2,MEA1,MSH2,NASP,NIPBL,PMFBP1,PYGO1,RNF8,SEPTIN2,SEPTIN7,SETD2,SETX,SMARCC1,STK4,TDRD6,TESK1,ZGLP1,ZNF35 |
| GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 7.0e-07 | 4.7e-05 | 899 | 664 | 32 | ACTR1A,ALMS1,ANKRD17,ATRX,CDK5RAP2,CHMP1A,CLSPN,CNTRL,E2F1,INO80,KMT2E,MAEA,MDM2,MSH2,NIPBL,PCNA,PCNT,RAD9B,RB1,RBL1,RDX,SEPTIN7,SLF2,SMC3,SPDL1,TAOK1,TP73,VPS4B,ZFYVE19,ZNF268,ZNF655,ZWINT |
| GO_POLY_A_PLUS_MRNA_EXPORT_FROM_NUCLEUS | 7.0e-07 | 5.2e-05 | 899 | 19 | 6 | GLE1,HHEX,MCM3AP,NXF1,THOC2,ZC3H11A |
| GO_PROTEIN_ACETYLATION | 9.0e-07 | 6.6e-05 | 899 | 202 | 16 | BAZ1A,BRD8,BRPF3,CEP295,CTCF,EP400,EPC1,EPC2,HCFC1,KAT6A,MCM3AP,MEAF6,NAA40,RSF1,SETD5,TAOK1 |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 1.1e-06 | 7.9e-05 | 899 | 1180 | 46 | AMFR,CCDC115,CUL5,DDX6,DHX9,E2F1,EDC4,FBXO17,FBXW7,FUS,GLMN,HNRNPD,HNRNPM,KHSRP,KLHL20,LYG1,MAEA,MDM2,MOV10,MTA1,NEMF,NUP214,PAN3,POP1,PPP2R5C,PPT1,QRICH2,RAB12,RDX,RNF111,RNF144A,RNF168,RNF8,SMARCC1,TIRAP,TMEM67,TOPORS,TRIR,UBAP1L,UBL7,UBXN2A,USP49,USP5,USP8,VPS4B,WWP1 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 1.1e-06 | 7.7e-05 | 899 | 1881 | 64 | ACIN1,ADM,ANKRD17,ASAP1,ASPA,ASXL1,ASXL2,BGLAP,BLOC1S6,CAMK2A,CAMSAP2,CAPRIN1,CBFB,CD46,CDK5RAP2,CNTF,CPNE9,CTTN,DDR2,DDX6,DNM1L,DOCK7,DVL2,E2F1,FBXW7,FRS2,H3C13,H3C7,H4C5,HDAC1,HOOK3,HOXA5,INPP5F,KDM3A,KMT2D,KMT2E,LEP,LIMS1,LNPK,MALT1,MDM2,MINAR1,MOV10,NF1,NIPBL,NUMBL,PTPRQ,RB1,RREB1,SDHAF2,SETD1A,SETX,SHOX2,SRGAP2,SRGAP2C,SRSF6,STK4,SUZ12,TBX19,TP73,ULK4,WNT3,ZNF268,ZNF804A |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 1.2e-06 | 8.0e-05 | 899 | 649 | 31 | ADM,BBS4,CCDC62,CHD8,DHX35,DVL2,FLVCR1,GLMN,HCFC1,HOXA5,INTU,KDM2B,KIAA1217,MBTD1,MSH2,NASP,NF1,NIPBL,PLCG1,PLOD3,POU5F1,RIC8A,SETD2,SHOX2,SMPD4,STK4,TBX15,TBX19,TCAP,TRAF3IP1,TULP3 |
| GO_MICROTUBULE_BASED_MOVEMENT | 1.2e-06 | 7.9e-05 | 899 | 283 | 19 | ACTR1A,AP3M1,BBS4,BLOC1S3,BLOC1S6,DNAH6,DNHD1,GAS8,HSPB11,HTT,KIF1B,KIF4B,KIF5B,KTN1,LAMP1,MAP4,SFPQ,TRAF3IP1,TTC21B |
| GO_CYTOSOLIC_TRANSPORT | 1.3e-06 | 8.5e-05 | 899 | 159 | 14 | ANKFY1,HOOK3,KIF1B,KIF5B,KLHL20,LAMP1,PIK3C3,RDX,SGSM2,TBC1D10B,VAMP3,VPS29,VPS53,WASHC2A |
| GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 1.3e-06 | 8.6e-05 | 899 | 586 | 29 | ADAR,ARID4B,BAZ1B,CTCF,DEK,DGCR8,DHX9,EPC1,GLMN,H3C13,H3C7,H4C5,HDAC1,HELZ,HNRNPA2B1,IPO8,KMT2D,MOV10,MPHOSPH8,MTA1,NAA40,NUP214,POLR2A,POM121,POM121C,POU5F1,SMARCA5,SUZ12,TAF1C |
| GO_NEURON_DEVELOPMENT | 1.4e-06 | 9.2e-05 | 899 | 1114 | 44 | ADM,ARFGEF1,ASAP1,BBS4,BLOC1S3,BLOC1S6,CABP4,CAMK2A,CAMSAP2,CAPRIN1,CNTF,CPNE9,CTTN,DNM1L,DOCK10,DOCK7,DVL2,FRS2,GNGT1,INPP5F,KIF5B,LEP,MAP4,MAPK7,MDM2,MINAR1,MOV10,NUMBL,PLCG1,PPT1,PSPN,RB1,SEPTIN2,SETX,SHOX2,SRGAP2,SRGAP2C,STK4,SZT2,THOC2,TOPORS,ULK4,WNT3,ZNF804A |
| GO_NEUROGENESIS | 1.7e-06 | 1.1e-04 | 899 | 1625 | 57 | ADM,ARFGEF1,ASAP1,ASPA,BBS4,BLOC1S3,BLOC1S6,CABP4,CAMK2A,CAMSAP2,CAPRIN1,CDK5RAP2,CNTF,CPNE9,CSK,CTTN,DDX6,DNM1L,DOCK10,DOCK7,DVL2,E2F1,FRS2,GNGT1,HDAC1,HOOK3,INPP5F,KIF5B,LEP,MAP4,MAPK7,MBOAT7,MDM2,MINAR1,MOV10,NF1,NIPBL,NUMBL,PLCG1,PPT1,PSPN,RB1,SEPTIN2,SETX,SHOX2,SMARCE1,SRGAP2,SRGAP2C,STK4,SZT2,THOC2,TOPORS,TP73,TULP3,ULK4,WNT3,ZNF804A |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 1.9e-06 | 1.2e-04 | 899 | 1016 | 41 | ACTR1A,ADAM20,ADM,AFF4,AMH,ARID4B,ASH1L,ATRX,B4GALNT1,BBS4,CATSPER2,CATSPERB,CATSPERG,CD46,DDX6,DZIP1,E2F1,FKBP6,HSPB11,KDM2B,KDM3A,KMT2D,LEP,M1AP,MAST2,MCM9,MEA1,MSH2,PMFBP1,PRDM9,PYGO1,RNF8,SEPTIN2,SEPTIN7,SETX,SPACA6,TDRD6,TESK1,WNT3,ZGLP1,ZNF35 |
| GO_REGULATION_OF_SISTER_CHROMATID_COHESION | 1.9e-06 | 1.2e-04 | 899 | 22 | 6 | ATRX,CTCF,NIPBL,RB1,SFPQ,SLF2 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 2.0e-06 | 1.3e-04 | 899 | 534 | 27 | ALMS1,ARFGEF1,ARHGEF5,BBS4,CAMSAP2,CAPZA1,CDK5RAP2,CEP295,CHMP1A,CLIP1,CNTRL,CTTN,DIAPH1,FCHSD2,KIRREL1,RBM14,RDX,SKA2,SMC3,TAOK1,TESK1,TMEM67,TRAF3IP1,VPS4B,WASF1,WHAMM,WHAMMP3 |
| GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 2.1e-06 | 1.3e-04 | 899 | 267 | 18 | ATRX,BANP,CHD3,E2F1,E2F2,EHMT1,FOXM1,HDAC1,KAT6A,MDM2,MEAF6,MSH2,MTA2,PCNA,RAD9B,TAF3,TOPORS,TP73 |
| GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | 2.4e-06 | 1.5e-04 | 899 | 297 | 19 | ANKLE1,CHD1L,CPSF1,DCLRE1A,DGCR8,EDC4,GTF2H1,MGME1,MOV10,PAN3,PCF11,PCNA,PGAP1,POLD3,POP1,RAD9B,REXO1,TOE1,TRIR |
| GO_PEPTIDYL_LYSINE_ACETYLATION | 2.4e-06 | 1.5e-04 | 899 | 168 | 14 | BAZ1A,BRD8,BRPF3,CTCF,EP400,EPC1,EPC2,HCFC1,KAT6A,MCM3AP,MEAF6,NAA40,RSF1,SETD5 |
| GO_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 2.5e-06 | 1.5e-04 | 899 | 326 | 20 | ARID2,ATG14,CAMSAP2,CAPZA1,CHMP1A,DVL2,EIF5AL1,GFM2,GLE1,KIF5B,MRPL45,MTRF1,RDX,SETX,SMARCC1,SMARCE1,SMCR8,SYNJ1,TAOK1,VPS4B |
| GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME | 2.5e-06 | 1.5e-04 | 899 | 83 | 10 | ATRX,CTCF,GNL3L,MCM9,MSH2,NIPBL,RB1,SETD2,SLF2,SPDL1 |
| GO_MITOTIC_SISTER_CHROMATID_COHESION | 2.6e-06 | 1.6e-04 | 899 | 23 | 6 | ATRX,NIPBL,PDS5A,PDS5B,RB1,SLF2 |
| GO_DNA_DEPENDENT_DNA_REPLICATION | 2.7e-06 | 1.6e-04 | 899 | 146 | 13 | ATRX,BAZ1A,BOD1L1,CCNE2,GINS2,GMNN,INO80,MCM3,MCM4,MCM9,MGME1,PCNA,POLD3 |
| GO_PROTEIN_ACYLATION | 2.8e-06 | 1.7e-04 | 899 | 246 | 17 | BAZ1A,BRD8,BRPF3,CEP295,CTCF,EP400,EPC1,EPC2,HCFC1,KAT6A,MCM3AP,MEAF6,NAA40,RSF1,SETD5,TAOK1,ZDHHC9 |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 3.1e-06 | 1.8e-04 | 899 | 547 | 27 | ACIN1,ARID2,ATG14,CAMSAP2,CAPZA1,CHMP1A,CTTN,DDR2,DNM1L,DVL2,EIF2D,EIF5AL1,FBXW7,GFM2,GLE1,HTT,KIF5B,MRPL45,MTRF1,RDX,SETX,SMARCC1,SMARCE1,SMCR8,SYNJ1,TAOK1,VPS4B |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 3.4e-06 | 2.0e-04 | 899 | 1823 | 61 | ADAR,AKT1S1,ARHGEF5,ASH1L,ATG14,BOD1L1,CAMKK1,CCNE2,CHRM5,CLSPN,CNTF,CSK,DDR2,DOCK7,DVL2,EIF3A,FBXW7,FOXM1,FRS2,GLMN,GTF2H1,HHEX,HTT,INPP5F,KIRREL1,LAT,LEP,MALT1,MAP3K6,MOB1B,NECAB2,NEK1,NEK4,NF1,NUP214,OSBPL8,PARP16,PILRB,POM121,POM121C,PPP1R12A,PPP1R7,PPP2R5C,QARS1,RB1,RBL1,SH3BP5L,SLC7A14,SLK,SMCR8,STK4,TAOK1,TESK1,TIRAP,TP73,TRAF3IP1,TTN,UBE2V1,ULK4,UNC119,ZBTB20 |
| GO_REGULATION_OF_PHOSPHORYLATION | 3.6e-06 | 2.1e-04 | 899 | 1625 | 56 | ADAR,AKT1S1,ARHGEF5,ASH1L,ATG14,CAMKK1,CCNE2,CLSPN,CNTF,CSK,DDR2,DOCK7,DVL2,EIF3A,FBXW7,FOXM1,FRS2,GLMN,GTF2H1,HHEX,HTT,INPP5F,KIRREL1,LAT,LEP,MALT1,MAP3K6,MOB1B,NECAB2,NEK1,NEK4,NF1,NUP214,OSBPL8,PARP16,PILRB,POM121,POM121C,PPP2R5C,QARS1,RB1,RBL1,SH3BP5L,SLK,SMCR8,STK4,TAOK1,TESK1,TIRAP,TP73,TRAF3IP1,TTN,UBE2V1,ULK4,UNC119,ZBTB20 |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 4.0e-06 | 2.3e-04 | 899 | 655 | 30 | ARHGEF5,ATG14,CAMKK1,CLSPN,CSK,DCUN1D1,DDR2,DVL2,FBXW7,FRS2,HNRNPA2B1,HNRNPD,LAT,LEP,MALT1,MAP3K6,MOB1B,NEK1,NEK4,OSBPL8,PARP16,PILRB,SLK,STK4,TAOK1,TIRAP,TOPORS,TP73,UBE2V1,UNC119 |
| GO_ENDOSOMAL_TRANSPORT | 4.5e-06 | 2.6e-04 | 899 | 228 | 16 | ALMS1,ANKFY1,AP5M1,CHMP1A,DNM1L,GRIPAP1,INPP5F,SGSM2,SNX4,TBC1D10B,VAMP3,VPS29,VPS4B,VPS50,VPS53,WASHC2A |
| GO_MISMATCH_REPAIR | 4.6e-06 | 2.6e-04 | 899 | 38 | 7 | MCM9,MSH2,PCNA,PMS2P3,POLD3,SETD2,TP73 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 4.6e-06 | 2.6e-04 | 899 | 526 | 26 | ARHGEF5,ASAP1,BBS4,CDK5RAP2,CEP295,CHD1L,CLIP1,CTTN,DEF8,DZIP1,EPS8L3,FCHSD2,GTF2H1,HAS3,HTT,KIRREL1,LIMS1,PAN3,PIEZO1,SEPTIN7,SLF2,TESK1,VPS4B,WASF1,WHAMM,WHAMMP3 |
| GO_REGULATION_OF_GENE_SILENCING | 4.8e-06 | 2.7e-04 | 899 | 154 | 13 | ADAR,DHX9,H3C13,H3C7,H4C5,IPO8,MPHOSPH8,NAA40,NUP214,POLR2A,POM121,POM121C,POU5F1 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 4.8e-06 | 2.7e-04 | 899 | 432 | 23 | ARFGEF1,ARHGEF5,ASAP1,BBS4,CAMSAP2,CAPZA1,CDK5RAP2,CHD1L,CLIP1,CTTN,DNM1L,FCHSD2,GTF2H1,HCFC1,KIRREL1,PIEZO1,RB1,RDX,SLF2,TRAF3IP1,WASF1,WHAMM,WHAMMP3 |
| GO_NEURON_DIFFERENTIATION | 5.0e-06 | 2.8e-04 | 899 | 1365 | 49 | ADM,ARFGEF1,ASAP1,BBS4,BLOC1S3,BLOC1S6,CABP4,CAMK2A,CAMSAP2,CAPRIN1,CDK5RAP2,CNTF,CPNE9,CTTN,DDX6,DNM1L,DOCK10,DOCK7,DVL2,FRS2,GNGT1,HDAC1,INPP5F,KIF5B,LEP,MAP4,MAPK7,MDM2,MINAR1,MOV10,NUMBL,PLCG1,PPT1,PSPN,RB1,SEPTIN2,SETX,SHOX2,SRGAP2,SRGAP2C,STK4,SZT2,THOC2,TOPORS,TP73,TULP3,ULK4,WNT3,ZNF804A |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 5.0e-06 | 2.8e-04 | 899 | 802 | 34 | ANKRD13A,CCNE2,CD84,CSK,DHX9,DIAPH1,E2F1,EFCAB7,EPB41L2,FBXW7,GAS8,GNL3L,GRIPAP1,HPS4,HTT,INPP5E,INPP5F,KIF5B,LAMP1,LEP,MDM2,NECAB2,NF1,NIPBL,NUP214,PCNT,PLCG1,PPP1R12A,RB1,RDX,SETD2,SNX4,TP73,TTC21B |
| GO_PROTEIN_LOCALIZATION_TO_CILIUM | 5.3e-06 | 2.9e-04 | 899 | 54 | 8 | BBS4,CPLANE1,DZIP1,EFCAB7,GAS8,INPP5E,TTC21B,TULP3 |
| GO_HISTONE_H3_K9_METHYLATION | 5.5e-06 | 3.0e-04 | 899 | 39 | 7 | ARID4B,ASH1L,ATRX,EHMT1,KDM3A,PRDM9,SETD5 |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 5.9e-06 | 3.2e-04 | 899 | 406 | 22 | ACTR1A,AP3M1,BBS4,BBS5,BLOC1S3,BLOC1S6,CD84,CDK5RAP2,CHMP1A,DOCK7,HOOK3,HTT,KIF1B,KIF5B,LAMP1,LAT,MAP4,MLPH,SNX4,SPDL1,SYNJ1,VPS4B |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 6.1e-06 | 3.2e-04 | 899 | 669 | 30 | ACTA1,ALMS1,ARFGEF1,ARHGEF5,BBS4,CAMSAP2,CAPZA1,CDK5RAP2,CLIP1,CTTN,DDR2,DIAPH1,FCHSD2,HOOK3,KIRREL1,MDM2,NF1,PLOD3,RB1,RDX,SLK,TAOK1,TCAP,TESK1,TNXB,TTN,WASF1,WDR73,WHAMM,WHAMMP3 |
| GO_REGULATION_OF_CHROMOSOME_ORGANIZATION | 6.2e-06 | 3.3e-04 | 899 | 347 | 20 | ALKBH4,ATRX,CDK5RAP2,CTCF,GNL3L,HNRNPA2B1,HNRNPD,KDM3A,KMT2E,MPHOSPH8,NAA40,NIPBL,PRDM9,RB1,SETD1A,SETD5,SFPQ,SLF2,SPDL1,TLK1 |
| GO_RESPONSE_TO_HORMONE | 6.4e-06 | 3.4e-04 | 899 | 994 | 39 | ACACA,ACTA1,ADM,AKR1C2,BBS4,BGLAP,CAMK2A,CATSPER2,CATSPERB,CATSPERG,CBFB,CCDC62,CHRM5,CSK,GRK2,HDAC1,HHEX,HNRNPD,KBTBD2,KDM3A,KMT2D,LEP,MBD5,MDM2,NASP,NCOA6,OSBPL8,PCNA,PIAS2,PLOD3,RAB12,RB1,RBM14,RDX,SMARCC1,SRSF6,TRIM68,USP8,ZNF106 |
| GO_RECOMBINATIONAL_REPAIR | 7.0e-06 | 3.7e-04 | 899 | 136 | 12 | FUS,GINS2,INO80,MCM3,MCM4,MCM9,NIPBL,RAD51D,RAD52,SETD2,SFPQ,TP53BP1 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | 7.3e-06 | 3.8e-04 | 899 | 74 | 9 | ARHGEF5,ASAP1,BBS4,CEP295,DZIP1,HTT,PAN3,SEPTIN7,VPS4B |
| GO_FOREBRAIN_DEVELOPMENT | 7.9e-06 | 4.1e-04 | 899 | 383 | 21 | ATRX,BBS4,DOCK7,E2F1,FRS2,HDAC1,HOOK3,KDM2B,KIF5B,MBOAT7,NF1,NUMBL,PGAP1,PHLPP2,SETD2,SRGAP2,SRGAP2C,SZT2,TBX19,TRA2B,TTC21B |
| GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 8.0e-06 | 4.1e-04 | 899 | 353 | 20 | ATRX,BRCC3,DEK,DHX9,FOXM1,FUS,GNL3L,HNRNPA2B1,HNRNPD,MPHOSPH8,MSH2,PCNA,PRDM9,RAD52,RNF168,RNF8,SETD2,SLF2,TP53BP1,UBE2V1 |
| GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY | 8.0e-06 | 4.1e-04 | 899 | 57 | 8 | CRNKL1,DDX23,LUC7L3,PRPF6,RBM5,SCAF11,SETX,SRSF6 |
| GO_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING | 8.5e-06 | 4.3e-04 | 899 | 116 | 11 | ADAR,DHX9,H3C13,H3C7,H4C5,IPO8,NUP214,POLR2A,POM121,POM121C,POU5F1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 9.1e-06 | 4.6e-04 | 899 | 356 | 20 | ATRX,BRCC3,CDK5RAP2,CLSPN,E2F1,EHMT1,EPC1,MDM2,PCNA,RB1,RBL1,RBM14,SEPTIN7,SPDL1,SUZ12,TAOK1,TMEM67,ZFYVE19,ZNF268,ZNF655 |
| GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION | 9.6e-06 | 4.8e-04 | 899 | 17 | 5 | GINS2,MCM3,MCM4,PCNA,POLD3 |
| GO_HISTONE_H2A_ACETYLATION | 9.6e-06 | 4.8e-04 | 899 | 17 | 5 | BRD8,EP400,EPC1,MEAF6,NAA40 |
| GO_MYELOID_CELL_DIFFERENTIATION | 1.0e-05 | 4.9e-04 | 899 | 420 | 22 | ACIN1,ADAR,BGLAP,CBFB,FBXW7,FLVCR1,H3C13,H3C7,H4C5,HDAC1,HOXA5,KAT6A,KMT2D,KMT2E,MAEA,MOV10,NCOA6,NF1,RB1,SETD1A,TET2,TIRAP |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 1.0e-05 | 4.9e-04 | 899 | 687 | 30 | ASAP1,BBS4,CAMSAP2,CAPRIN1,CNTF,CPNE9,CTTN,DEF8,DNM1L,DVL2,DZIP1,EPS8L3,HTT,INPP5F,MAP4,MDM2,MINAR1,MOV10,ODF2L,RDX,RREB1,SEPTIN7,SETX,SHOX2,SRGAP2C,TTC21B,ULK4,VDAC3,WNT3,ZNF804A |
| GO_SMOOTHENED_SIGNALING_PATHWAY | 1.0e-05 | 4.9e-04 | 899 | 141 | 12 | DZIP1,FAM92A,GAS8,HSPB11,INTU,RB1,SEPTIN2,SHOX2,TRAF3IP1,TTC21B,TTC23,TULP3 |
Num: 1 (Pathways: 567 DK: 9)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (9) | ADCK1, ADCK5, CDC42BPG, COQ8B, MAST3, NEK9, PRAG1, STK32A, TAOK2 |
| Light Kinase (28) | BCR, BRD3, CKMT1A, CKMT1B, EIF2AK1, EPHA7, EPHB6, ERBB4, KDR, LIMK1, MAP3K13, MAP3K5, MAP4K2, MINK1, PRKACA, PRKCA, PRKCH, PRKX, PTK2B, ROCK2, RPS6KA2, SGK1, STK11, STK38, TGFBR2, TNK2, TRIM66, UHMK1 |
| Non-kinase Count | 1088 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1405 | 114 | AASDH,ABCD2,ABCD3,ABHD15,ACADSB,ACP6,ACSM2B,ADH4,ADIPOQ,ADORA1,AGRN,AIG1,ALDH3A2,ALDH5A1,ALG1,AMACR,ASAH2,ATP8B1,B3GALT1,BCL11B,BCO1,BCO2,BPNT1,CDS1,CHKA,CLCN2,CPTP,CRAT,CROT,CRPPA,CRYL1,CYP2R1,CYP2U1,CYP4V2,DGAT2,ECHDC3,EFR3A,ELOVL6,ERLIN2,ESR1,ETFDH,ETNK2,FADS3,FAR2,FITM2,GBA2,GDE1,GDPD5,GM2A,GOLM1,GPD1L,GPLD1,HELZ2,HINT2,HSD17B8,IGFBP7,INPP4A,IRS1,JAZF1,LDLRAP1,LIPE,LPCAT3,LPCAT4,LPL,MECR,MLYCD,MMAA,NR1H4,NUDT7,P2RX1,PBX1,PCTP,PDE3B,PEX2,PEX7,PIGM,PIGN,PIGX,PLA2G12A,PLA2G2C,PLAAT3,PLCB2,PLCD3,PLPP6,PLPPR2,PMVK,PPARA,PPP2R5A,PTGS1,PTK2B,PTPN13,RAB4A,RGL1,SCAP,SCARB1,SDC3,SGMS1,SIRT3,SLC35C1,SLC44A1,SMARCD3,SNCA,SORL1,SPTLC3,SREBF1,ST6GALNAC3,SULT1A4,TEX2,TM7SF2,TWIST1,VAV3,WDR91,YWHAH,ZP3 |
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 1625 | 121 | ACAP3,ADAM10,ADCY1,AGRN,ANK3,ANKS1A,APBB1,ARL3,ATP7A,ATP8B1,BCHE,BCL11B,BTBD2,C1QL1,CD9,CDON,CELSR2,CLN5,CRPPA,CRTC1,DISC1,DIXDC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,ERBB4,ERCC2,EVL,FAT4,FBXW8,FGF5,FN1,FZD1,FZD3,FZD4,GAS6,GBA2,GDF11,GDPD5,GJA1,GLI2,GLI3,GPR157,HERC1,HIF1A,HMG20B,ID1,IDH2,ITGA3,JAG2,KIF3A,LAMA1,LHFPL5,LIG4,LIMK1,LLGL1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,MINK1,MYEF2,MYH10,NAGLU,NIN,NPTN,NREP,NRTN,PBX1,PDZD7,PEX7,PICK1,PLXND1,PPP1R9B,PRAG1,PRKCA,PRKCH,PTCH1,PTK2B,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SGK1,SKI,SLC12A5,SLC9A3R1,SLC9A6,SMARCD3,SORL1,SPOCK1,SPRY3,STK11,STMN3,STXBP1,SUN1,TAOK2,TBC1D24,TENM3,TIAM1,TRAK2,TRAPPC9,TWIST1,UCN,UHMK1,VCL,WNT11,YWHAH,ZNF365,ZSWIM5 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1962 | 133 | AASDH,ABCD2,ABCD3,ACADSB,ACPP,ACSM2B,ADCY1,ADCY9,ADH4,ADIPOQ,AIG1,ALDH3A2,ALDH4A1,ALDH5A1,ALDH7A1,AMACR,ARPP19,ASAH2,ATP5F1D,ATP7A,ATP8B1,ATPSCKMT,B4GAT1,BCKDHB,BCO1,BCO2,BPHL,BPNT1,BRAT1,BTD,CDS1,CEMIP2,CHKA,CHST12,CHST2,CHST7,CHSY3,CKMT1A,CKMT1B,CLCN2,COQ8B,CRAT,CROT,CRYL1,CSAD,CYB5A,CYP2R1,CYP2U1,CYP4V2,DDAH1,DGAT2,DHFR2,DHTKD1,ECHDC3,ELOVL6,ENPP1,ENTPD8,ERLIN2,ETFDH,FADS3,FAR2,FOXO1,FPGT,GBA2,GDE1,GDPGP1,GLCE,GMPR,GPLD1,H6PD,HIF1A,HLCS,HSD17B8,HYAL2,IDH2,INPP4A,IRS1,ITPK1,LDLRAP1,LHPP,LIPE,LPL,LRP5,MAGI3,MAT2A,MAT2B,MECR,MINPP1,MLYCD,MMAA,MPC1,MRI1,MRS2,MT-CO2,MTHFR,NDST3,NR1H4,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,NUP210,PAPSS1,PARS2,PCYOX1L,PEX2,PEX7,PFKFB2,PLAAT3,PLCB2,PLCD3,PLPP6,PMVK,PPARA,PTGS1,PTK2B,SCAP,SCARB1,SLC25A12,SLC46A1,SNCA,SREBF1,SRR,SULT1A4,SUOX,TM7SF2,TST,TWIST1,TYMP,UROS,UXS1,XYLT2 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 1545 | 115 | ABCD2,ABLIM1,ABLIM2,ACAP3,ADAM10,ADCY1,AGRN,ANK3,APBB1,ARHGEF26,ARHGEF4,ARL3,ARMC2,ATP7A,ATP8B1,BBS10,BBS2,BCL11B,CDC14B,CDC42EP3,CELSR2,CFAP221,CFAP44,CROCC,CRPPA,CRTC1,DISC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,EVI5L,EVL,FAT4,FBXW8,FHDC1,FN1,FZD1,FZD3,FZD4,GALNT11,GDPD5,GJA1,GLI2,GLI3,HERC1,ID1,IFT81,ITGA3,KIF3A,LAMA1,LAMA5,LHFPL5,LIMK1,LLGL1,LPAR1,LRRC56,LRRC7,MAP3K13,MCF2,METRN,MIEN1,MINK1,MYH10,NIN,NPTN,NREP,NRTN,PDZD7,PICK1,PLXND1,PPP1R9B,PRAG1,PRKACA,PRKCA,PTCH1,PTK2B,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SGK1,SLC12A5,SLC9A3R1,SLC9A6,SNX1,SNX10,SPOCK1,SPRY3,STK11,STMN3,STXBP1,TANC1,TAOK2,TBC1D24,TENM3,TIAM1,TRAK2,TTLL1,UCN,UHMK1,VAV3,VCL,YWHAH,ZNF365,ZSWIM5 |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 1365 | 106 | ACAP3,ADAM10,ADCY1,AGRN,ANK3,ANKS1A,APBB1,ARL3,ATP7A,ATP8B1,BCL11B,C1QL1,CDON,CELSR2,CLN5,CRPPA,CRTC1,DISC1,DIXDC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,ERBB4,ERCC2,EVL,FAT4,FBXW8,FN1,FZD1,FZD3,FZD4,GBA2,GDF11,GDPD5,GJA1,GLI2,GLI3,HERC1,HIF1A,HMG20B,ID1,ITGA3,JAG2,KIF3A,LAMA1,LHFPL5,LIMK1,LLGL1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,MINK1,MYEF2,MYH10,NAGLU,NIN,NPTN,NREP,NRTN,PBX1,PDZD7,PICK1,PLXND1,PPP1R9B,PRAG1,PRKCA,PTCH1,PTK2B,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SGK1,SLC12A5,SLC9A3R1,SLC9A6,SPOCK1,SPRY3,STK11,STMN3,STXBP1,TAOK2,TBC1D24,TENM3,TIAM1,TRAK2,TRAPPC9,UCN,UHMK1,VCL,WNT11,YWHAH,ZNF365,ZSWIM5 |
| GO_NEURON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 1114 | 94 | ACAP3,ADAM10,ADCY1,AGRN,ANK3,ANKS1A,APBB1,ARL3,ATP7A,ATP8B1,BCL11B,C1QL1,CELSR2,CLN5,CRPPA,CRTC1,DISC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,EVL,FAT4,FBXW8,FN1,FZD1,FZD3,FZD4,GBA2,GDPD5,GJA1,GLI2,GLI3,HERC1,ID1,ITGA3,KIF3A,LAMA1,LHFPL5,LIMK1,LLGL1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,MINK1,MYH10,NAGLU,NIN,NPTN,NREP,NRTN,PDZD7,PICK1,PLXND1,PPP1R9B,PRAG1,PRKCA,PTCH1,PTK2B,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SGK1,SLC12A5,SLC9A3R1,SLC9A6,SPOCK1,SPRY3,STK11,STMN3,STXBP1,TAOK2,TBC1D24,TENM3,TIAM1,TRAK2,UCN,UHMK1,VCL,YWHAH,ZNF365,ZSWIM5 |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 1141 | 95 | ADAM10,ADCY1,AGRN,ANK3,ANTXR1,APBB1,ARHGEF26,ATP7A,BCL11B,BCL9L,BVES,C1GALT1C1,CASP9,CD9,CDC42EP3,CDH12,CDH17,CDH18,CDH7,CDH8,CELSR2,CRPPA,CSRP1,DISC1,DLG4,DNM3,EFNB2,EPHA7,ERCC2,EVL,FAT1,FBXW8,FITM2,FN1,FZD3,FZD4,GJA1,GLI2,GLI3,HEG1,ID1,ITGB1BP1,KDR,KIF3A,LAMA1,LAMA5,LHFPL5,LIMK1,LLGL1,LPAR1,LRATD1,MAP3K13,MCF2,METRN,MINK1,MYH10,NBEAL2,NIN,NPTN,NRTN,PDZD7,PECAM1,PLXND1,PRAG1,PRKCA,PTCH1,PTK2B,PTPRM,RAB3A,RHOBTB1,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SLC9A3R1,SLC9A6,SNX1,SPINT2,SSH2,STK11,STXBP1,TAOK2,TIAM1,TMOD2,TRAK2,VCL,YWHAH,ZNF365,ZSWIM5 |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1064 | 91 | AASDH,ABCD2,ABCD3,ABHD15,ACADSB,ACP6,ACSM2B,ADH4,ADIPOQ,AGRN,AIG1,ALDH3A2,ALDH5A1,ALG1,AMACR,ASAH2,B3GALT1,BCO1,BCO2,BPNT1,CDS1,CHKA,CPTP,CRAT,CROT,CRPPA,CRYL1,CYP2U1,CYP4V2,DGAT2,ECHDC3,EFR3A,ELOVL6,ERLIN2,ETFDH,ETNK2,FADS3,FITM2,GBA2,GDE1,GM2A,GPD1L,GPLD1,HSD17B8,INPP4A,IRS1,LIPE,LPCAT3,LPCAT4,LPL,MECR,MLYCD,MMAA,NR1H4,NUDT7,P2RX1,PCTP,PEX2,PEX7,PIGM,PIGN,PIGX,PLA2G12A,PLA2G2C,PLAAT3,PLCB2,PLPP6,PLPPR2,PMVK,PPARA,PTGS1,PTK2B,PTPN13,RAB4A,SCAP,SCARB1,SDC3,SGMS1,SIRT3,SLC35C1,SLC44A1,SNCA,SORL1,SPTLC3,SREBF1,ST6GALNAC3,TEX2,TWIST1,VAV3,WDR91,ZP3 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 1881 | 125 | ACAP3,ADAM10,ADIPOQ,AGO1,APBB1,ARRB2,ASH2L,BCL11B,BCL9L,CCDC85B,CDON,CITED1,CRTC1,CTNNBIP1,DISC1,DIXDC1,DLG4,DNM3,EFNB2,ENC1,ENPP1,EPHA7,ERBB4,FAM20C,FAT4,FBXW8,FN1,FOXO1,FOXP1,FSTL3,FZD1,FZD3,FZD4,GAS6,GDF11,GDPD5,GJA1,GLI2,GLI3,H3C10,H3C12,H4C9,HIF1A,HIF1AN,HMG20B,ID1,IDH2,IL18,IRF4,ITGA3,ITGB1BP1,KDR,LIG4,LILRB3,LIMK1,LMO2,LPAR1,LPL,LRP5,LRRC7,MAP3K13,MAP3K5,MCF2,MEN1,METRN,NIN,NPTN,NREP,PBX1,PKP2,PLXND1,PPARA,PRAG1,PRICKLE1,PRKACA,PRKCA,PRKCH,PRKX,PTCH1,PTK2B,PURB,RAB7B,RAG1,RECK,RFLNB,RGCC,ROBO2,ROCK2,RTN4R,RUNX1T1,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINB13,SERPINI1,SKI,SMAD6,SMARCD3,SMOC1,SORL1,SORT1,SOX13,SPOCK1,STAT1,STK11,TCFL5,TENM3,TFAP2A,TGFBR2,TIAM1,TNFSF14,TNRC6C,TRAK2,TRIM58,TRIM6,TWIST1,VSIR,YWHAH,ZHX3,ZNF365,ZSWIM5 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1117 | 92 | ACP6,ACPP,ACSM2B,ADCY1,ADCY9,AGRN,ALDH5A1,ALG1,ALG1L,ATP5F1D,ATP7A,ATPSCKMT,B3GALT1,B3GAT3,B4GAT1,BPNT1,C1GALT1C1,C1GALT1C1L,CEMIP2,CHST12,CHST2,CHST7,CHSY3,COG7,CPTP,CROT,CRPPA,CRYL1,DGAT2,DHFR2,DHTKD1,DPY19L1,DPY19L3,ELOVL6,ENPP1,FAR2,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GBA2,GLCE,GM2A,GMPR,GPD1L,GPLD1,GXYLT2,H6PD,HIF1A,HS3ST1,HSD17B8,HYAL2,ITM2A,LFNG,MAGI3,MAN1A1,MGAT5B,MLYCD,MPC1,MT-CO2,MUC2,NAGLU,NDST3,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,NUP210,PAPSS1,PFKFB2,PIGM,PIGN,PIGX,PMVK,POGLUT1,POGLUT3,PPARA,SDC3,SLC25A12,SLC35C1,SNCA,ST6GALNAC3,SULF1,SULT1A4,TMTC2,TMTC3,TRAK2,TYMP,UXS1,XYLT2 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1125 | 1665 | 114 | ADAM10,ADCY1,ADIPOQ,ADORA1,ADRB2,AGO1,AGRN,AP2A2,ARHGEF19,ARRB1,ARRB2,BCHE,BCL9L,BCR,CDH8,CELSR2,CHRM3,CHRNA9,CHRNE,CITED1,CMAHP,CRTC1,CTNNBIP1,CXADR,CXXC4,DISC1,DIXDC1,DLG4,EFNB2,ENPEP,ESR1,EXOC3L1,FAT1,FGF12,FGF5,FGFBP3,FOXO1,FZD1,FZD3,FZD4,GJA1,GJC1,GLI2,GLI3,GLRB,GPLD1,GRHL3,HIF1A,HTR1D,IL18,IRS1,ITGA3,JUP,LGR4,LRP5,LYPD6,MINK1,MPP2,NOVA1,NPTN,NR1H4,P2RX1,PARD6A,PCDH17,PCDHB2,PCSK1,PFKFB2,PICK1,PKP2,PLCB2,PPFIA3,PPP1R9B,PRICKLE1,PRICKLE2,PRKACA,PRKCA,PTK2B,RAB11FIP1,RAB26,RAB3A,RAPGEF4,RECK,RNF207,SCN1B,SEMA4F,SEMA5A,SEPTIN5,SIRT3,SKI,SLC12A5,SLC9A3R1,SNAP47,SNCA,SNX19,SORCS2,SOST,SREBF1,STK11,STXBP1,STXBP4,SULF1,SYNJ2BP,TIAM1,TM7SF3,TMOD2,TNFRSF11A,TNRC6C,UCN,UNC13B,VANGL1,VGF,VPS18,WNT11,YWHAH |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 1125 | 1425 | 104 | ADAM10,ADIPOQ,AGR2,ANK3,ANTXR1,BCR,BVES,CD200,CD9,CDH12,CDH17,CDH18,CDH7,CDH8,CDON,CELSR2,CLDN11,CLDN16,CLDN9,COL28A1,CSRP1,CXADR,CYTH3,DENND6A,DGCR2,DISC1,DLG3,DLG4,DUSP22,EFNB2,EPB41L4B,EPHA7,FAT1,FAT4,FGFRL1,FN1,FRMD5,FSTL3,FZD4,GAS6,GLI2,GLI3,ID1,IGFBP7,IL18,ITGA3,ITGB1BP1,JAG2,JCAD,JUP,KDR,KLRC4-KLRK1,LAMA1,LAMA5,LGALS3BP,LRFN3,LRRC7,MCAM,MEN1,MINK1,MYH10,NPTN,PCDH17,PCDH18,PCDH7,PCDHA3,PCDHB2,PCDHGB4,PDE3B,PDZD2,PECAM1,PKP2,PLXND1,PODXL2,PPARA,PRKCA,PRKX,PTK2B,PTPRM,RAG1,RGCC,ROBO2,ROCK2,SCARB1,SCN1B,SEMA5A,SERPINI1,SMAD6,SPINT2,SPOCK1,STXBP1,SUSD5,SYNJ2BP,TAOK2,TENM3,TGFBR2,THBS2,TIAM1,TMEM8B,TNFSF14,VAV3,VCL,VSIR,ZP3 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1125 | 1781 | 118 | ACAP3,ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB1,ADRB2,AGRN,ANK3,ANTXR1,ARHGAP24,ARHGAP28,ARHGEF19,ARRB1,ASAP3,ATP7A,ATPSCKMT,B3GAT3,BCR,BEX1,C6orf89,CARD10,CASP9,CCDC125,CCNYL1,CCS,CD200,CDC14B,CHML,CLN5,CRADD,CRTC1,DLG3,DLG4,ELMOD1,ERCC2,ESR1,EVI5L,FN1,FZD1,FZD4,GAS6,GM2A,GNB5,GPLD1,GPSM1,GRHL3,H1-0,HIF1A,HIP1,HSPA2,IL18,IQSEC1,IRF4,IRS1,ITGB1BP1,JUP,LFNG,LLGL1,LLGL2,LPAR1,MAP3K13,MAP3K5,MAP4K2,MAPRE2,MEN1,MINK1,MTCL1,NLRP1,NLRP2,P2RX1,PARM1,PFKFB2,PLCB2,PLXND1,PPM1H,PRKACA,PRKCH,PTK2B,RAB3A,RAB4A,RAB7B,RALGAPA2,RASA4,RGCC,RINL,RNF207,ROCK2,RTN4R,SCARB1,SGK1,SHC2,SIPA1L2,SKI,SLX4,SNCA,SORL1,SRGAP1,STIM2,STK11,TAOK2,TBC1D16,TBC1D2,TBC1D24,TBC1D8,TCAF1,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,TRAPPC9,TRIM34,TRIM6,TWIST1,UCN,VAV3,VSIR,WNT11 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1125 | 1930 | 123 | ABHD17A,ADAM10,ADIPOQ,ADORA1,AGR2,AGRN,AMACR,ANK3,AP2A2,APPL1,ARL3,B3GAT3,BBS2,BCR,C12orf66,CARD10,CEP68,CHML,CHMP7,COG7,COPG2,CRAT,CROCC,CROT,DISC1,DLG3,DLG4,DNM3,EFNB2,EFR3A,ERBB4,ESR1,EVI5L,EXOC3L1,GAS2L1,GAS6,GGA3,GJA1,GLI3,GLRB,GOPC,GPD1L,GPHN,GSTK1,HYAL2,ID1,IFT81,IK,IMMP2L,ITGA3,ITGB1BP1,JUP,KIF3A,LAMA5,LDLRAP1,LMNA,LRRC7,MAPRE2,MLYCD,MRAP2,MTCL1,NPTN,NUDT7,NUP210,NXF3,PACS2,PARD6A,PEX1,PEX2,PEX7,PICK1,PKIA,PKP2,PPP1R9B,PPP2R5A,PRICKLE1,PRKACA,PRKCH,PTCH1,PTPN14,RAB26,RAB3A,RAB3D,RAB4A,RAB7B,RANBP6,RASSF5,REEP2,ROCK2,RRAGA,SH3BP4,SLC9A3R1,SNAP47,SNX1,SNX10,SORCS2,SORL1,SPIDR,SREBF1,STK11,STX17,STXBP1,STXBP4,SUN1,SYNJ2BP,TAOK2,TBC1D16,TBC1D2,TBC1D8,TCAF1,TIAM1,TRAK2,TRAM1L1,TRAM2,UHMK1,UNC93B1,VCL,VPS18,WNT11,YWHAH,ZDHHC14,ZDHHC20,ZDHHC24 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 748 | 72 | ADAM10,ADCY1,AGRN,ANK3,ANTXR1,APBB1,ARHGEF26,BCL11B,BVES,C1GALT1C1,CASP9,CELSR2,CRPPA,DISC1,DLG4,DNM3,EFNB2,EPHA7,EVL,FAT1,FBXW8,FN1,FZD3,FZD4,GLI2,GLI3,HEG1,ID1,ITGB1BP1,KIF3A,LAMA1,LAMA5,LHFPL5,LIMK1,LLGL1,MAP3K13,MCF2,METRN,MINK1,MYH10,NBEAL2,NIN,NPTN,NRTN,PDZD7,PECAM1,PLXND1,PRKCA,PTCH1,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A3R1,SLC9A6,SPINT2,STK11,STXBP1,TAOK2,TIAM1,TRAK2,VCL,YWHAH,ZNF365,ZSWIM5 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 1163 | 91 | ADAM10,ADCK1,ADIPOQ,AGO1,AP2A2,ARHGEF19,ARRB2,BASP1,BCL9L,BCR,BVES,CARD10,CDC42EP3,CELSR2,CEMIP2,CITED1,COL4A2,DDAH1,DISC1,DLG4,DNM3,EFNB2,EPHA7,ESR1,FBXW8,FITM2,FN1,FOXP1,FZD1,FZD3,FZD4,GJA1,GRHL3,HIF1A,HIF1AN,HSPB6,ID1,ITGB1BP1,JCAD,JUP,KDR,LFNG,LGR4,LIMK1,LPAR1,MAP3K13,MCF2,METRN,MYH10,NIN,ODAPH,PARD6A,PDE3B,PLXND1,POGLUT1,PRAG1,PRICKLE1,PRICKLE2,PRKCA,PTK2B,PTPRM,RECK,RGCC,RHOBTB1,RNF207,ROBO2,ROCK2,RTN4R,SARM1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A3R1,STAT1,STK11,SULF1,SYNJ2BP,TAOK2,TFAP2A,TGFBR2,THBS2,TIAM1,TNFSF14,TRAK2,TWIST1,VANGL1,WNT11,YWHAH,ZSWIM5 |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1125 | 1984 | 124 | ACAP3,ADAM10,ADIPOQ,ADORA1,AGRN,ANKS1A,APPL1,ARMC2,ARRB2,ASAP3,ATP7A,BBS2,BCL11B,BCR,BRAT1,BVES,CARD10,CAVIN1,CCDC125,CD200,CD9,CELSR2,CFAP44,CRPPA,CXADR,DISC1,DIXDC1,DUSP22,EFNB2,ENPEP,EPB41L4B,EPHA7,ERBB4,EVL,FAT1,FN1,FOXP1,FRMD5,FZD3,FZD4,GAS6,GJA1,GLI2,GLI3,GPLD1,HIF1A,HTR1D,HYAL2,ID1,IDH2,IGHV4-34,IQSEC1,ITGA3,ITGB1BP1,JCAD,JUP,KDR,KIF3A,KLRC4-KLRK1,LAMA1,LAMA5,LMNA,LPAR1,LRATD1,MAPRE2,MCAM,MIEN1,MINK1,MYH10,NPTN,NRTN,OR1D2,PECAM1,PEX7,PLXND1,PODXL2,PPP1R9B,PRAG1,PRKCA,PRKX,PTCH1,PTK2B,PTPRM,RECK,RGCC,RHOBTB1,ROBO2,ROCK2,SAA2,SCARB1,SCN1B,SDC3,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SKI,SLC9A3R1,SNCA,SORL1,SOX18,SPINT2,SPOCK1,SRGAP1,SULF1,SUN1,SYNJ2BP,TAOK2,TCAF1,TGFBR2,TIAM1,TNFRSF11A,TNFSF14,TTLL1,TWIST1,TYMP,VAV3,VCL,VSIR,WNT11,ZP3,ZSWIM5 |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 1175 | 90 | ADAM10,AGO1,ANTXR1,ARHGAP24,ARRB2,ATP7A,BASP1,BVES,CARD10,CCM2,CEMIP2,CITED1,COL4A1,COL4A2,CXADR,DDAH1,EFNB2,ENPEP,ERBB4,FAT4,FBXW8,FGF12,FGFRL1,FN1,FOXO1,FZD1,FZD4,GALNT11,GJA1,GJC1,GLI2,GLI3,GPLD1,HEG1,HIF1A,HIF1AN,HSPB6,ID1,IL18,IMMP2L,ITGA3,ITGB1BP1,JARID2,JCAD,JUP,KDR,LAMA1,LAMA5,LMNA,LOXL1,LRP5,LUZP1,MCAM,MYH10,PDE3B,PECAM1,PKP2,PLCD3,PLXND1,POGLUT1,PPARA,PRICKLE1,PRKCA,PRKX,PTCD2,PTCH1,PTK2B,PTPN14,PTPRM,RECK,RGCC,RNF207,ROBO2,ROCK2,SEMA5A,SMAD6,SMARCD3,SOX18,STAT1,STK11,SULF1,SYNJ2BP,TGFBR2,THBS2,THSD7A,TWIST1,TYMP,VAV3,WNT11,XIRP2 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1164 | 89 | AASDH,ABCD2,ABCD3,ACADSB,ACSM2B,ADH4,ADIPOQ,AIG1,ALDH3A2,ALDH4A1,ALDH5A1,ALDH7A1,AMACR,ASAH2,ATP7A,ATP8B1,B4GAT1,BCKDHB,BCO2,BPHL,BPNT1,BTD,CEMIP2,CHST12,CHST2,CHST7,CHSY3,CKMT1A,CKMT1B,CRAT,CROT,CRYL1,CSAD,CYB5A,CYP2R1,CYP2U1,CYP4V2,DDAH1,DGAT2,DHFR2,DHTKD1,ECHDC3,ELOVL6,ENPP1,ERLIN2,ETFDH,FADS3,GBA2,GLCE,HIF1A,HLCS,HSD17B8,HYAL2,IDH2,IRS1,LIPE,LPL,MECR,MINPP1,MLYCD,MMAA,MPC1,MRI1,MRS2,MTHFR,NDST3,NR1H4,NUDT7,NUP210,PAPSS1,PARS2,PCYOX1L,PEX2,PEX7,PFKFB2,PPARA,PTGS1,SCAP,SLC25A12,SLC46A1,SNCA,SREBF1,SRR,SULT1A4,SUOX,TST,TWIST1,UROS,XYLT2 |
| GO_TUBE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 1122 | 87 | AGO1,AGR2,ARHGAP24,ATP7A,BASP1,CARD10,CCM2,CEMIP2,CITED1,COL4A1,COL4A2,CTNNBIP1,DDAH1,EFNB2,ENPEP,EPHA7,ESR1,FAT4,FN1,FOXP1,FSTL3,FZD1,FZD3,FZD4,GDF11,GJA1,GJB5,GJC1,GLI2,GLI3,GPLD1,GRHL3,HEG1,HIF1A,HIF1AN,HSPB6,ID1,IL18,IRX2,ITGA3,ITGB1BP1,ITPK1,JCAD,JUP,KDR,LAMA1,LAMA5,LGR4,LRP5,LUZP1,MCAM,MTHFR,PBX1,PDE3B,PECAM1,PLCD3,PLXND1,PRICKLE1,PRKACA,PRKCA,PRKX,PTCH1,PTK2B,PTPRM,RAB3A,RECK,RGCC,RNF207,ROBO2,ROCK2,SEMA5A,SKI,SMAD6,SOX18,SPINT2,SREBF1,SSBP3,STAT1,SULF1,SYNJ2BP,TGFBR2,THBS2,THSD7A,TWIST1,TYMP,VAV3,WNT11 |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1859 | 116 | AASDH,ABHD17A,ADCY1,ADCY9,ADIPOQ,AGO1,AGRN,ALDH3A2,ALDH7A1,ALG1,ALG1L,APBB1,ASAH2,ATG10,ATP5F1D,ATP7A,ATPSCKMT,B3GALT1,B3GAT3,B4GAT1,C1GALT1C1,C1GALT1C1L,CDS1,CHKA,CHST12,CHST2,CHST7,CHSY3,CKMT1A,CKMT1B,COG7,CRPPA,CSAD,DHFR2,DPY19L1,DPY19L3,EIF2AK1,ELOVL6,ENC1,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GLCE,GMPR,GPHN,GPLD1,GSPT2,GSTA4,GSTK1,GXYLT2,HABP4,HIF1A,HS3ST1,HSD17B8,IDH2,IL18,IRF4,ITM2A,LFNG,MAN1A1,MGAT5B,MLYCD,MMAA,MOCS1,MOCS3,MPC1,MRI1,MRPL33,MRPS28,MT-CO2,MTFMT,MTHFR,MTIF3,MUC2,NDST3,P2RX1,PAIP2B,PAPSS1,PARS2,PCSK1,PCTP,PIGM,PIGN,PIGX,POGLUT1,POGLUT3,PTK2B,ROCK2,SCAP,SDC3,SGMS1,SIRT3,SLC25A12,SLC25A39,SLC35C1,SLC44A1,SNCA,SPTLC3,SRR,ST6GALNAC3,TMTC2,TMTC3,TNRC6C,TRAK2,TYMP,UCN,UHMK1,UROS,XYLT2,ZDHHC14,ZDHHC20,ZDHHC24,ZDHHC8,ZNF540 |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1125 | 1051 | 81 | ADIPOQ,ADORA1,ADRB2,AGR2,ANKS1A,AP2A2,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,BCL9L,BCR,BDKRB2,CITED1,COL4A1,COL4A2,DUSP22,EFNB2,ENPP1,EPHA7,EPHB6,ERBB4,FAM20C,FAM83A,FAT4,FGF12,FGF5,FGFBP3,FGFRL1,FOXO1,FSTL3,FZD1,FZD4,GAS6,GDF11,GPLD1,HIF1A,HIP1,HTRA1,ID1,IRS1,ITGA3,JCAD,KDR,LIFR,MEN1,MVP,MYORG,NPTN,NR1H4,NREP,NRTN,PARD6A,PEG10,PRKCA,PTK2B,ROCK2,SESN3,SHC2,SKI,SKOR1,SLA,SLC9A3R1,SLC9A6,SMAD6,SNCA,SORL1,SORT1,SOST,SPRY3,SREBF1,STK11,STXBP4,SULF1,TGFBR2,TIAM1,TNK2,VAV3,ZFYVE28 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1033 | 80 | ACP6,ACPP,ACSM2B,ADCY1,ADCY9,ALDH5A1,ATP5F1D,ATPSCKMT,BPNT1,CDS1,CHKA,CKMT1A,CKMT1B,CROT,CRYL1,DGAT2,DHTKD1,EFR3A,ELOVL6,ENPP1,ENTPD8,ETNK2,FAR2,FITM2,GDE1,GMPR,GPD1L,GPHN,GPLD1,H6PD,HIF1A,HSD17B8,IDH2,INPP4A,IRS1,ITPK1,LHPP,LPCAT3,LPCAT4,LPL,MAGI3,MINPP1,MLYCD,MOCS1,MOCS3,MPC1,MT-CO2,NR1H4,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,NUP210,PAPSS1,PCTP,PFKFB2,PIGM,PIGN,PIGX,PLA2G12A,PLA2G2C,PLAAT3,PLCB2,PLCD3,PLPPR2,PMVK,PPARA,PTK2B,PTPN13,RAB4A,SCARB1,SGMS1,SLC25A12,SLC44A1,SNCA,SULT1A4,VAV3,WDR91,ZP3 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1318 | 92 | ABCD2,ADIPOQ,ADORA1,ADRB1,ADRB2,AGO1,ARRB1,ARRB2,BBS2,BCR,CARD10,CD200,CD9,CITED1,COL4A2,CPTP,DIXDC1,DNM3,EFNB2,ENPP1,EPHA7,ERBB4,EVL,FN1,FOXO1,FSTL3,FZD3,GAS6,GDF11,GJA1,GLI2,GLI3,H4C9,HIF1A,ID1,IDH2,ITGB1BP1,JARID2,JUP,LFNG,LGR4,LILRB3,LMNA,LPAR1,LRP5,MCF2,MEN1,NOVA1,NOVA2,NPTN,NR1H4,PBX1,PCTP,PDE3B,PPARA,PRAG1,PRICKLE1,PRKACA,PTCH1,PTK2B,PTPRM,RAB11FIP1,RFLNB,RGCC,ROBO2,ROCK2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPING1,SKI,SMAD6,SORL1,SOST,SPOCK1,STAT1,STK11,SULF1,SYNJ2BP,TGFBR2,THBS2,TRAK2,TWIST1,UBE2L6,UCN,VSIR,WNT11,YWHAH,ZNF365 |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 1177 | 86 | AGO1,ARHGAP24,ATP7A,ATP8B1,CARD10,CASP9,CD9,CDON,CEMIP2,COL4A1,COL4A2,CSRP1,DDAH1,EFNB2,ENPEP,ERCC2,ERVW-1,FAM20C,FN1,FOXO1,FZD1,FZD3,GJA1,GLI2,GLI3,GPLD1,GRHL3,HERC1,HIF1A,HSPB6,HTRA1,ID1,IL18,IRX2,ITGA3,ITGB1BP1,JCAD,JUP,KDR,LAMA5,LFNG,LUZP1,MCAM,MTHFR,MYH10,NBEAL2,ODAPH,PDE3B,PECAM1,PLCD3,PLXND1,POGLUT1,PPARA,PRICKLE1,PRKACA,PRKCA,PRKX,PTCH1,PTK2B,PTPN14,PTPRM,RECK,RGCC,ROBO2,ROCK2,SEMA5A,SKI,SMARCD3,SOX18,SPINT2,SSBP3,STAT1,SULF1,SYNJ2BP,TANC1,TFAP2A,TGFBR2,THBS2,THSD7A,TMOD2,TNFSF14,TWIST1,TYMP,VAV3,WNT11,ZP3 |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 592 | 59 | ADAM10,ADCY1,AGRN,ANK3,APBB1,BCL11B,CELSR2,CRPPA,DISC1,DLG4,DNM3,EFNB2,EPHA7,EVL,FBXW8,FN1,FZD3,GLI2,GLI3,ID1,KIF3A,LAMA1,LHFPL5,LIMK1,LLGL1,MAP3K13,MCF2,METRN,MINK1,MYH10,NIN,NPTN,NRTN,PDZD7,PLXND1,PRKCA,PTCH1,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A3R1,SLC9A6,STK11,STXBP1,TAOK2,TIAM1,TRAK2,VCL,YWHAH,ZNF365,ZSWIM5 |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 1125 | 1758 | 109 | ACAP3,ADAM10,ADIPOQ,ADORA1,ANKS1A,APPL1,ARMC2,ARRB2,ASAP3,ATP7A,BBS2,BCL11B,BCR,BRAT1,BVES,CARD10,CAVIN1,CCDC125,CD200,CD9,CELSR2,CFAP44,CXADR,DISC1,DIXDC1,DUSP22,EFNB2,ENPEP,EPB41L4B,ERBB4,EVL,FAT1,FN1,FOXP1,FRMD5,FZD3,GAS6,GJA1,GLI3,GPLD1,HIF1A,HYAL2,ID1,IDH2,IGHV4-34,IQSEC1,ITGA3,ITGB1BP1,JCAD,JUP,KDR,KLRC4-KLRK1,LAMA1,LAMA5,LMNA,LPAR1,LRATD1,MAPRE2,MCAM,MIEN1,MINK1,MYH10,NRTN,PECAM1,PEX7,PLXND1,PODXL2,PPP1R9B,PRAG1,PRKCA,PRKX,PTK2B,PTPRM,RECK,RGCC,RHOBTB1,ROCK2,SAA2,SCARB1,SDC3,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SKI,SLC9A3R1,SORL1,SOX18,SPINT2,SPOCK1,SRGAP1,SULF1,SUN1,SYNJ2BP,TAOK2,TCAF1,TGFBR2,TIAM1,TNFRSF11A,TNFSF14,TTLL1,TWIST1,VAV3,VCL,VSIR,WNT11,ZP3 |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 1125 | 1680 | 106 | ACPP,ADAM10,ADCY1,ADIPOQ,ADORA1,AGR2,AP2A2,APBB1,ARRB1,ATP6V0A1,ATP7A,ATP7B,BCR,BDKRB2,C1QTNF4,CAVIN1,CD200,CD9,CELSR2,CHRM3,COMMD3,COPG2,CPTP,ERBB4,EXOC2,EXOC3L1,F8,FN1,FOXP1,FZD4,GAS6,GHDC,GJA1,GM2A,GPLD1,HABP4,HIF1A,HYAL2,IDH2,IQGAP2,IRS1,JUP,LGALS3BP,LGR4,LILRB3,LLGL1,LLGL2,LPL,LRP5,LRRC7,MAOB,MICAL3,MT-CO2,MVP,MYH10,NBEAL2,NLRP1,NLRP2,NR1H4,P2RX1,PARD6A,PCDH7,PCYOX1L,PECAM1,PFKFB2,PHACTR2,PLA2G12A,PLA2G2C,PPFIA3,PRKCA,PRSS12,PYGB,RAB11FIP1,RAB26,RAB3A,RAB3D,RAPGEF4,RGCC,SEPTIN1,SEPTIN5,SERGEF,SERPING1,SGK1,SIRT3,SLC51A,SLC9A3R1,SNAP47,SNCA,SNX10,SNX19,SORL1,SREBF1,STXBP1,STXBP4,TIAM1,TM7SF3,TNFRSF11A,TRAPPC1,TRIM6,TWIST1,UCN,UNC13B,VCL,VGF,VPS18,ZP3 |
| GO_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1692 | 106 | ABCD3,ADORA1,ADRB2,ANK3,ARRB2,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,ATP8B1,ATP8B3,ATPSCKMT,BDKRB2,CALHM3,CCS,CHRNA9,CHRNE,CLCN2,CLDN16,COMMD3,CPTP,CROT,CYB5A,DLG3,DLG4,ENPP1,FGF12,GAS6,GJA1,GJC1,GLRB,GNB5,GOPC,GPD1L,HSPA2,KCNJ1,LHFPL5,LRRC7,LRRC8B,MAOB,MFSD3,MINK1,MPC1,MRS2,MT-CO2,NR1H4,P2RX1,PCTP,PITPNC1,PKP2,PLA2G12A,PLA2G2C,PLCB2,PLCD3,PPARA,PPFIA3,PRAF2,PRKACA,PTK2B,RAB3A,RNF207,SCARB1,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC16A12,SLC22A18,SLC25A12,SLC25A18,SLC25A23,SLC25A29,SLC25A42,SLC30A4,SLC35A1,SLC36A1,SLC44A1,SLC46A1,SLC4A4,SLC51A,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SPG7,STIM2,STXBP1,SURF1,TCAF1,TG,TMEM175,TMEM37,TMEM63C,TNFRSF11A,TPCN1,TTYH3,TWIST1,UCN,UNC13B,WWP2,YWHAH |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1604 | 102 | ABCA3,ABCD2,ABCD3,ADIPOQ,ADRB2,ANK3,APPL1,ARPP19,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,ATP8B1,ATPSCKMT,BCR,CDH17,CHRNA9,CHRNE,CLCN2,CLDN16,CYB5A,DLG3,DLG4,ENPP1,ERLIN2,FGF12,GAS6,GJA1,GJC1,GLRB,GNB5,GOPC,GPD1L,GPR155,HSPA2,IRS1,KCNJ1,LRRC7,LRRC8B,MFSD3,MINK1,MPC1,MRS2,MT-CO2,P2RX1,PEX1,PEX2,PEX7,PLCB2,PLCD3,PRAF2,PRKACA,PTK2B,RNF207,SCARB1,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC16A12,SLC22A18,SLC25A12,SLC25A18,SLC25A23,SLC25A29,SLC25A42,SLC30A4,SLC35A1,SLC35A5,SLC35C1,SLC36A1,SLC44A1,SLC45A1,SLC46A1,SLC4A4,SLC51A,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SORT1,SPG7,STIM2,STXBP4,SURF1,TCAF1,TMEM175,TMEM37,TMEM63C,TPCN1,TRAM1L1,TRAM2,TST,TTYH3,TWIST1,WWP2,YWHAH |
| GO_TUBE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 928 | 74 | AGO1,AGR2,ARHGAP24,CARD10,CCM2,CEMIP2,CITED1,COL4A1,COL4A2,CTNNBIP1,DDAH1,EFNB2,ENPEP,EPHA7,ESR1,FAT4,FN1,FOXP1,FZD1,FZD3,FZD4,GJC1,GLI2,GLI3,GPLD1,GRHL3,HEG1,HIF1A,HIF1AN,HSPB6,ID1,IL18,IRX2,ITGB1BP1,JCAD,JUP,KDR,LAMA1,LAMA5,LGR4,LRP5,LUZP1,MCAM,MTHFR,PBX1,PDE3B,PECAM1,PLCD3,PLXND1,PRICKLE1,PRKACA,PRKCA,PRKX,PTCH1,PTK2B,PTPRM,RECK,RGCC,RNF207,ROCK2,SEMA5A,SKI,SOX18,SPINT2,STAT1,SULF1,SYNJ2BP,TGFBR2,THBS2,THSD7A,TWIST1,TYMP,VAV3,WNT11 |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 1287 | 89 | ACAP3,ADRB1,AGRN,ANTXR1,ARHGAP24,ARHGAP28,ARHGEF19,ARPP19,ARRB1,ARRB2,ASAP3,B3GAT3,BCR,BVES,C6orf89,CASP9,CCDC125,CD200,CHML,COL28A1,CRADD,CSRNP3,DLG3,ELFN2,ELMOD1,EPHA7,ESR1,EVI5L,FN1,GAS6,GM2A,GNB5,GPLD1,GPSM1,GRHL3,HIP1,HSPA2,IQGAP2,IQSEC1,ITGB1BP1,KLRC4-KLRK1,LLGL1,LLGL2,LPAR1,LPL,MAP3K5,MAPRE2,MARF1,MTCL1,NLRP1,NLRP2,P2RX1,PHACTR2,PLCB2,PLXND1,PPP1R9B,PPP2R5A,PTK2B,RAB3A,RAB4A,RAG1,RALGAPA2,RASA4,RECK,RINL,ROCK2,RTN4R,SERPINB13,SERPING1,SERPINI1,SH3BP4,SIPA1L2,SNCA,SORL1,SORT1,SPINT2,SPOCK1,SRGAP1,STMN3,TBC1D16,TBC1D2,TBC1D24,TBC1D8,TIAM1,TNFSF14,TNK2,VAV3,VSIR,WNT11 |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1894 | 112 | ADCY1,ADIPOQ,ADORA1,ADRB2,ANK3,APBB1,APPL1,ARPP19,ARRB1,ARRB2,ATP7A,ATPSCKMT,B3GAT3,BCR,BVES,C1QTNF4,CD200,CLCN2,CPTP,DLG3,DLG4,DNAJC6,DNM3,EFNB2,ENPP1,FGF12,FN1,FOXP1,GAS6,GJA1,GLI3,GNB5,GOPC,GPD1L,GPLD1,HIF1A,HIP1,HSPA2,HYAL2,IDH2,IRS1,ITGB1BP1,JUP,KCNJ1,LDLRAP1,LGR4,LPL,LRP5,LRRC7,MAOB,MINK1,MTCL1,MYH10,NLRP1,NLRP2,NR1H4,P2RX1,PARD6A,PCDH17,PFKFB2,PICK1,PKIA,PKP2,PPARA,PRKACA,PRKCA,PTCH1,PTK2B,PTPN14,RAB11FIP1,RAB26,RAB3A,RAB3D,RAB4A,RAPGEF4,REEP2,REEP6,RGCC,RNF207,SCARB1,SCN1B,SEPTIN1,SEPTIN5,SERGEF,SGK1,SIRT3,SLC9A3R1,SNCA,SORL1,SREBF1,STIM2,STXBP1,STXBP4,SYNJ2BP,TCAF1,TIAM1,TM7SF3,TMEM14A,TMEM37,TNFRSF11A,TNK2,TPCN1,TRIM58,TRIM6,TWIST1,UCN,UHMK1,UNC13B,VPS18,WWP2,YWHAH,ZP3 |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 810 | 68 | ADAM10,AGO1,ANTXR1,ARHGAP24,ATP7A,CARD10,CCM2,CEMIP2,CITED1,COL4A1,COL4A2,DDAH1,EFNB2,ENPEP,FBXW8,FN1,FOXO1,FZD4,GJC1,GLI3,GPLD1,HEG1,HIF1A,HIF1AN,HSPB6,ID1,IL18,IMMP2L,ITGB1BP1,JCAD,JUP,KDR,LAMA1,LAMA5,LOXL1,LRP5,LUZP1,MCAM,MYH10,PDE3B,PECAM1,PLCD3,PLXND1,POGLUT1,PRICKLE1,PRKCA,PRKX,PTK2B,PTPN14,PTPRM,RECK,RGCC,ROBO2,ROCK2,SEMA5A,SMAD6,SOX18,STAT1,STK11,SULF1,SYNJ2BP,TGFBR2,THBS2,THSD7A,TWIST1,TYMP,VAV3,WNT11 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 1429 | 94 | ACAP3,ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB1,ADRB2,AGRN,ANTXR1,ARHGAP24,ARHGAP28,ARHGEF19,ARRB1,ASAP3,ATP7A,ATPSCKMT,B3GAT3,BCR,C6orf89,CARD10,CASP9,CCDC125,CCNYL1,CCS,CD200,CDC14B,CHML,CRADD,DLG3,DLG4,ELMOD1,ESR1,EVI5L,FN1,FZD4,GAS6,GM2A,GNB5,GPLD1,GRHL3,HIF1A,HIP1,HSPA2,IL18,IQSEC1,IRS1,ITGB1BP1,LLGL1,LLGL2,LPAR1,MAP3K13,MAP3K5,MAP4K2,MAPRE2,MINK1,MTCL1,NLRP1,NLRP2,P2RX1,PARM1,PFKFB2,PLCB2,PPM1H,PRKACA,PTK2B,RAB3A,RAB4A,RALGAPA2,RASA4,RGCC,RINL,ROCK2,RTN4R,SCARB1,SHC2,SIPA1L2,SLX4,SNCA,SORL1,SRGAP1,STK11,TAOK2,TBC1D16,TBC1D2,TBC1D24,TBC1D8,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,UCN,VAV3,VSIR,WNT11 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1125 | 1716 | 105 | ADAM10,ADIPOQ,ADORA1,ARRB1,ASH2L,ATP7A,BCHE,BCL11B,CD200,CD9,CDON,CITED1,CTC1,CTNNBIP1,DDAH1,DIS3L2,DISC1,DLG3,DUSP22,EFNB2,EIF2AK1,ERBB4,ESR1,FGF5,FGFRL1,FN1,FOXO1,FOXP1,FZD3,GAS6,GDF11,GJA1,GLI2,GLI3,GPLD1,H2AC6,HIF1A,HTRA1,ID1,IDH2,IGFBP7,IL11RA,IL18,IRS1,ITGB1BP1,JAG2,JARID2,JCAD,JUP,KDR,KLF9,LAMA5,LDLRAP1,LIFR,LIG4,LMNA,LRP5,MAP3K5,MEN1,NUDT16,NUDT6,NUPR2,PBX1,PEX2,PLCD3,PPP1R9B,PRKCA,PRKCH,PTCH1,PTGS1,PTK2B,PTPN14,PTPRM,RASSF5,RGCC,RPS6KA2,SEMA5A,SGK1,SH3BP4,SKI,SLA,SLC9A3R1,SMAD6,SMARCD3,SOX18,SPINT2,SSBP3,STAT1,STK11,STXBP4,SULF1,SYNJ2BP,TBC1D8,TCFL5,TFAP2A,TGFBR2,TIAM1,TNFRSF11A,TNK2,TP53I11,TWIST1,VAV3,VSIR,WNT11,ZP3 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 928 | 73 | ACAP3,ADAM10,AGRN,APBB1,BCL11B,CDON,CRTC1,DISC1,DIXDC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,ERBB4,FBXW8,FN1,FZD1,FZD3,FZD4,GDF11,GDPD5,GLI2,GLI3,GRHL3,HIF1A,HMG20B,ID1,IDH2,ITGA3,LIG4,LIMK1,LPAR1,LRFN3,LRRC7,MAP3K13,MCF2,METRN,NIN,NPTN,NREP,PBX1,PLXND1,PRAG1,PRKACA,PRKCH,PTK2B,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SKI,SLC25A12,SMARCD3,SNCA,SORL1,SPOCK1,STK11,TENM3,TG,THBS2,TIAM1,TRAK2,TYMP,YWHAH,ZNF365,ZSWIM5 |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 1071 | 79 | ABLIM1,AGRN,AP2A2,ARHGEF19,ARRB2,BASP1,BBS2,BCL11B,BCR,CDON,CELSR2,CHRNA9,CITED1,CTNNBIP1,DGCR2,EFNB2,ESR1,EVL,FAM20C,FAT1,FAT4,FGFRL1,FOXN3,FOXO1,FZD1,FZD3,FZD4,GDF11,GLI2,GLI3,GRHL3,HEG1,HIF1A,HOXD8,HTRA1,HYAL2,ID1,IRX2,JAG2,LAMA1,LAMA5,LFNG,LGR4,LHFPL5,LRP5,NAGLU,ODAPH,PARD6A,PBX1,PDZD7,PEX7,PKP2,PLXND1,PPARA,PRICKLE1,PRICKLE2,PRKX,PTCD2,PTCH1,PTPRM,RFLNB,RNF207,ROBO2,SKI,SLC9A3R1,SMAD6,SMARCD3,SNX10,SOX18,STAT1,SULF1,TENM3,TFAP2A,TGFBR2,TIAM1,TWIST1,VANGL1,WNT11,XIRP2 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 1125 | 1703 | 104 | ABCD2,ADIPOQ,ADORA1,ADRB2,APPL1,ARRB1,ARRB2,ASAH2,BBS2,BCL9L,BCR,BDKRB2,C12orf66,CCDC125,CD200,CD9,CHRNA9,CITED1,CTNNBIP1,CXXC4,DDAH1,DUSP22,ENPP1,ERCC4,ESR1,EYA4,FBH1,FOXO1,FOXP1,FSTL3,FZD1,GAS6,GDPD5,GJA1,GLI3,GPD1L,HEG1,HIF1A,HIF1AN,HTRA1,HYAL2,IRF4,IRS1,ITGA3,ITGB1BP1,JAG2,KLRC4-KLRK1,LFNG,LGR4,LMNA,LPAR1,LPL,MAGEF1,MEIS3,MEN1,MRAP2,NR1H4,PDE3B,PEG10,PPARA,PRICKLE1,PRKACA,PTCH1,RAB7B,RADX,RASA4,RGS19,ROBO2,RTN4R,SARM1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPING1,SESN3,SH3BP4,SIRT3,SKI,SKOR1,SLC35C1,SLC9A3R1,SMAD6,SNCA,SORL1,SOST,SPRY3,STAT1,STK11,STK38,STMN3,SULF1,SYNJ2BP,TGFBR2,TMEM14A,TNFAIP8L1,TSPAN6,TWIST1,UCN,WNT11,WWP2,ZFYVE28,ZKSCAN3 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1741 | 105 | ABCD3,ADIPOQ,ADORA1,ADRB2,AMACR,ANK3,AP2A2,APPL1,ARL3,ATP5F1D,ATPSCKMT,B3GAT3,BACH2,BCR,BVES,CAPZA2,CCDC91,CHML,CHMP7,CITED1,CLN5,COG2,COG7,COPG2,CRAT,CROT,DOP1B,EVI5L,F8,F8A1,F8A3,FYCO1,GAS6,GEMIN8,GGA3,GLI3,GOPC,GSTK1,HIF1A,HYAL2,IFT81,IMMP2L,ITGB1BP1,JUP,KIF3A,LDLRAP1,LMNA,LRRC7,MLYCD,MTCL1,MYH10,NUDT7,NUP210,NXF3,PEX1,PEX2,PEX7,PHETA1,PICK1,PKIA,PRICKLE1,PRKACA,PTPN14,RAB26,RAB3A,RAB3D,RAB4A,RAB7B,RANBP6,REEP2,REEP6,SLC9A3R1,SNX1,SORCS2,SORL1,SORT1,SPG7,SPIRE2,SREBF1,STX17,STXBP1,STXBP4,SUN1,SYNJ2BP,TAOK2,TBC1D16,TBC1D2,TBC1D8,TCAF1,TRAK2,TRAM1L1,TRAM2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9,TRIM58,UHMK1,UNC93B1,VPS18,WDR91,YWHAH,ZDHHC14,ZDHHC20,ZDHHC24 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1825 | 108 | ADIPOQ,ADRB1,ADRB2,AGRN,APBB1,APPL1,ARRB2,ATPSCKMT,BASP1,BBS2,BCL9L,C1QTNF4,CD200,CDON,CHRM3,CRTC1,CTNNBIP1,DDAH1,DISC1,DLG4,EFNB2,ELOVL6,ENC1,EPB41L4B,ERBB4,FAM20C,FBXW8,FN1,FOXP1,FZD1,FZD3,FZD4,GAS6,GDPD5,GJA1,GLI2,GLI3,GPLD1,HEG1,HIF1A,HIF1AN,HMG20B,HSPB6,HYAL2,IL18,IQSEC1,IRF4,ITGA3,ITGB1BP1,JCAD,JUP,KDR,KLRC4-KLRK1,LDLRAP1,LGR4,LIG4,LIMK1,LPAR1,LPL,LRP5,LRRC7,MAP3K13,MAPRE2,METRN,MRTFB,NIN,NLRP1,NLRP2,NPTN,NR1H4,ODAPH,PLXND1,PRKCA,PRKCH,PTK2B,RAB7B,RAG1,RGCC,RNF207,ROBO2,ROCK2,SCARB1,SCN1B,SEMA5A,SERPINI1,SLC25A12,SMARCD3,SORL1,STAT1,STK11,SULF1,TENM3,TFAP2A,TGFBR2,THBS2,TIAM1,TNFRSF11A,TRIM58,TRIM6,TSPAN6,TWIST1,UCN,UNC13B,VSIR,WNT11,ZHX3,ZNF365,ZP3 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1047 | 77 | ADCK1,ADIPOQ,ADRB1,ADRB2,AGO1,BBS2,BCR,CARD10,CCDC85B,CITED1,COL4A2,DIXDC1,DNM3,EFNB2,ENPP1,EPHA7,ERBB4,FOXO1,FSTL3,FZD3,GAS6,GDF11,GJA1,GLI2,GLI3,H4C9,HIF1A,ID1,IDH2,IL18,ITGB1BP1,JARID2,LFNG,LILRB3,LPAR1,LRP5,MCF2,MEN1,PBX1,PDE3B,PKP2,PPARA,PRAG1,PRICKLE1,PRKACA,PTCH1,PTK2B,PTPRM,RFLNB,RGCC,ROBO2,ROCK2,RTN4R,RUNX1T1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SKI,SMAD6,SORL1,SORT1,SPOCK1,STAT1,STK11,SULF1,SYNJ2BP,TGFBR2,THBS2,TRAK2,TRIM6,TWIST1,WNT11,YWHAH,ZKSCAN3,ZNF365 |
| GO_CELL_PART_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 691 | 61 | ADAM10,ADCY1,AGRN,ANK3,APBB1,ATP7A,BCL11B,CELSR2,CRPPA,DISC1,DLG4,DNM3,EFNB2,EPHA7,EVL,FBXW8,FN1,FZD3,FZD4,GJA1,GLI2,GLI3,ID1,KIF3A,LAMA1,LIMK1,LLGL1,MAP3K13,MCF2,METRN,MINK1,MYH10,NIN,NPTN,NRTN,PLXND1,PRKCA,PTCH1,PTPRM,RAB3A,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SLC9A6,SNX1,STK11,STXBP1,TAOK2,TIAM1,TRAK2,VCL,YWHAH,ZNF365,ZSWIM5 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1005 | 75 | ABCD2,ABCD3,ACADSB,ADH4,ADIPOQ,ALDH3A2,ALDH4A1,ALDH5A1,ALDH7A1,AMACR,ATP5F1D,BCKDHB,BCO1,BCO2,CCS,CMAHP,CRAT,CROT,CRYL1,CYB5A,CYP2R1,CYP2U1,CYP4V2,DGAT2,DHFR2,DHRS12,DHTKD1,ENPP1,ETFDH,F8,FADS3,FAR2,GFOD1,GMPR,GPHN,GSTK1,H6PD,HIF1A,HIF1AN,HR,HSD17B8,IDH2,IFI30,IMMP2L,IRS1,LOXL1,MAOB,MECR,MICAL3,MLYCD,MRAP2,MT-CO2,MTHFR,NDUFB3,PCYOX1L,PEX2,PEX7,PPARA,PTGS1,PYGB,RFESD,SESN3,SIRT3,SLC25A12,SLC25A18,SLC25A23,SNCA,SUOX,SURF1,TM7SF2,TTC19,TWIST1,TXNRD3,UCN,VAT1L |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1823 | 107 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARPP19,ARRB1,ARRB2,ATP7A,ATPSCKMT,B3GAT3,BDKRB2,BRAT1,CAMK2N2,CARD10,CCNJL,CCNYL1,CDON,CHRNA9,CSRNP3,DLG3,DLG4,DUSP22,EIF2AK1,ELFN2,ENPP1,EPHA7,ERBB4,FAM20C,FBH1,FN1,FOXO1,FZD1,FZD4,GAS6,GDF11,GPD1L,GPLD1,HEG1,HIF1A,HSPA2,HYAL2,ID1,IL18,INKA2,IRS1,ITGB1BP1,JCAD,KDR,LPAR1,LRP5,MAGI3,MAP3K13,MAP3K5,MAP4K2,MARF1,MEN1,MINK1,MT-CO2,MVP,NPTN,NR1H4,NUP210,PARD6A,PECAM1,PFKFB2,PHACTR2,PKIA,PPARA,PPM1E,PPP1R9B,PPP2R5A,PRKACA,PRKCA,PTK2B,PTPN13,RGCC,ROCK2,SCARB1,SH3RF3,SHC2,SIRT3,SLC25A12,SLC25A23,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,STK11,STK38,SYNJ2BP,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TNK2,TPD52L1,TRIM6,TWIST1,UCN,VAV3,WDR91,WNT11,ZFYVE28,ZP3 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1125 | 1994 | 113 | ADAM10,ADCK1,ADCK5,ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,ARRB2,BCR,BDKRB2,BRAT1,CAMK2N2,CARD10,CCM2,CCNJL,CCNYL1,CDC42BPG,CDON,CHRNA9,DLG3,DLG4,DUSP22,EIF2AK1,ENPP1,EPHA7,EPHB6,ERBB4,ERCC2,FAM20C,FBH1,FGF5,FN1,FOXO1,FZD1,FZD4,GAS6,GDF11,GPD1L,HEG1,HSPA2,HYAL2,ID1,IL18,INKA2,IRS1,ITGB1BP1,JCAD,KDR,LAMA1,LIMK1,LIPE,LPAR1,LRP5,LRRC7,MAGI3,MAP3K13,MAP3K5,MAP4K2,MAST3,MEN1,MINK1,MVP,NEK9,NPTN,NRTN,PARD6A,PECAM1,PICK1,PKIA,PPM1E,PPP1R9B,PPP2R5A,PRAG1,PRKACA,PRKCA,PRKCH,PRKX,PTK2B,PTPN13,RASA4,RGCC,ROCK2,RPS6KA2,SGK1,SH3RF3,SHC2,SIRT3,SLA,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,STK11,STK32A,STK38,SULT1A4,SYNJ2BP,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TNK2,TPD52L1,TRIM6,TWIST1,UCN,UHMK1,WNT11,ZFYVE28 |
| GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1125 | 544 | 53 | AP2A2,ARHGEF19,ARRB2,ATP7A,CCM2,CELSR2,CITED1,COL4A1,CTNNBIP1,DLG3,EFNB2,EPHA7,ESR1,FAT4,FOXP1,FZD1,FZD3,FZD4,GJA1,GLI2,GLI3,GRHL3,HIF1A,IRX2,JAG2,LAMA1,LAMA5,LGR4,LRP5,LUZP1,MTHFR,PARD6A,PBX1,PLXND1,PRICKLE1,PRICKLE2,PRKACA,PRKX,PTCH1,RNF207,SKI,SLC9A3R1,SOX18,SPINT2,STAT1,SULF1,TFAP2A,TGFBR2,TIAM1,TWIST1,VANGL1,VCL,WNT11 |
| GO_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 1296 | 86 | ADIPOQ,AGR2,AP2A2,ARHGEF19,ARHGEF26,ARRB2,ATP7A,BASP1,BCL11B,BCR,CCM2,CELSR2,CITED1,COL4A1,CTNNBIP1,DLG3,DNASE1L2,EFNB2,EPHA7,ERBB4,ERCC2,ESR1,FAM20C,FAT1,FAT4,FOXP1,FZD1,FZD3,FZD4,GDF11,GJA1,GLI2,GLI3,GRHL3,GSTK1,HEG1,HIF1A,ID1,IRX2,ITPK1,JAG2,JUP,KDR,KRT80,LAMA1,LAMA5,LFNG,LGR4,LHFPL5,LRP5,LUZP1,MEN1,MTHFR,PARD6A,PBX1,PDZD7,PECAM1,PKP2,PLXND1,POGLUT1,PRICKLE1,PRICKLE2,PRKACA,PRKCH,PRKX,PTCH1,RNF207,ROBO2,ROCK2,SERPINB13,SKI,SLC9A3R1,SMAD6,SOX18,SPINT2,SSBP3,STAT1,SULF1,TFAP2A,TGFBR2,TIAM1,TST,TWIST1,VANGL1,VCL,WNT11 |
| GO_TISSUE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 670 | 59 | AP2A2,ARHGEF19,ARRB2,ATP7A,CCM2,CELSR2,CITED1,COL4A1,CTNNBIP1,DLG3,EFNB2,EPHA7,ESR1,FAT4,FOXP1,FZD1,FZD3,FZD4,GJA1,GLI2,GLI3,GRHL3,HEG1,HIF1A,IRX2,ITGA3,JAG2,LAMA1,LAMA5,LGR4,LRP5,LUZP1,MTHFR,PARD6A,PBX1,PKP2,PLXND1,PRICKLE1,PRICKLE2,PRKACA,PRKX,PTCD2,PTCH1,RNF207,ROBO2,SKI,SLC9A3R1,SOX18,SPINT2,STAT1,SULF1,TFAP2A,TGFBR2,TIAM1,TWIST1,VANGL1,VCL,WNT11,XIRP2 |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1935 | 110 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB1,ADRB2,ANK3,ARRB1,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,BBS10,BBS2,BCR,BDKRB2,CHRNA9,CLDN16,CLN5,CROCC,CRTC1,CTC1,CXADR,DGAT2,DISC1,DLG4,DMXL2,EIF2AK1,ELOVL6,ENPP1,ERCC2,ERCC4,ESR1,F2RL2,FGF12,FITM2,FOXO1,GAS6,GJA1,GPD1L,GPLD1,GPR157,GRHL3,H4C9,HIF1A,HYAL2,ID1,IL18,IRF4,IRS1,KDR,LDLRAP1,LGR4,LPAR1,LPL,LRP5,MEN1,MRAP2,MUC2,NOVA1,NOVA2,NPTN,NR1H4,P2RX1,PCTP,PLCB2,PLCD3,PRKACA,PRKCA,PTCH1,PTK2B,RAB3D,RAG1,SCARB1,SCN1B,SCNN1A,SCNN1G,SESN3,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SLX4,SNCA,SNX10,STAT1,STIM2,STK11,STXBP4,TIAM1,TMEM175,TMTC2,TNFRSF11A,TNFSF14,TPCN1,TRIM58,TRIM6,TXNRD3,UNC13B,VGF,YLPM1,ZBTB48,ZNF365 |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 671 | 59 | ADCY1,ADCY9,AGRN,ALG1,ALG1L,ATP5F1D,ATP7A,ATPSCKMT,B3GALT1,B3GAT3,B4GAT1,C1GALT1C1,C1GALT1C1L,CHST12,CHST2,CHST7,CHSY3,COG7,CRPPA,CRYL1,DHFR2,DPY19L1,DPY19L3,ELOVL6,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GLCE,GXYLT2,HS3ST1,HSD17B8,ITM2A,LFNG,MAN1A1,MGAT5B,MLYCD,MPC1,MT-CO2,MUC2,NDST3,PAPSS1,PIGM,PIGN,PIGX,POGLUT1,POGLUT3,SDC3,SLC25A12,SLC35C1,SNCA,ST6GALNAC3,TMTC2,TMTC3,TRAK2,TYMP,UXS1,XYLT2 |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1125 | 1427 | 91 | ADIPOQ,ADORA1,ADRB2,APPL1,ARRB1,ARRB2,ASAH2,BCHE,BCL9L,BDKRB2,C12orf66,CCDC125,CHRNA9,CITED1,CTNNBIP1,CXXC4,DUSP22,ENPP1,ESR1,EYA4,FOXO1,FOXP1,FSTL3,FZD1,GAS6,GDPD5,GJA1,GLI3,GPD1L,HEG1,HIF1A,HIF1AN,HTRA1,HYAL2,IRF4,IRS1,ITGA3,ITGB1BP1,JAG2,LFNG,LGR4,LMNA,LPAR1,MEIS3,MEN1,MRAP2,MVP,NR1H4,PCDH17,PDE3B,PEG10,PICK1,PRICKLE1,PRKACA,PTCH1,PTK2B,RAB11FIP1,RAB7B,RASA4,RGS19,SARM1,SESN3,SH3BP4,SIRT3,SKI,SKOR1,SLC35C1,SLC9A3R1,SMAD6,SNCA,SORCS2,SORL1,SOST,SPRY3,SREBF1,STAT1,STK11,STK38,STMN3,STXBP1,SULF1,SYNJ2BP,TGFBR2,TMEM14A,TNFAIP8L1,TSPAN6,TWIST1,UCN,WNT11,WWP2,ZFYVE28 |
| GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 654 | 58 | AASDH,ABCD2,ABCD3,ACADSB,ACSM2B,ADH4,ADIPOQ,AIG1,ALDH3A2,ALDH4A1,ALDH5A1,AMACR,ASAH2,ATP8B1,BCO2,BTD,CHST12,CKMT1A,CKMT1B,CRAT,CROT,CRYL1,CYP2U1,CYP4V2,DGAT2,DHTKD1,ECHDC3,ELOVL6,ERLIN2,ETFDH,FADS3,GBA2,HIF1A,HLCS,HSD17B8,IDH2,IRS1,LIPE,LPL,MECR,MLYCD,MMAA,MPC1,MRS2,NR1H4,NUDT7,NUP210,PEX2,PEX7,PFKFB2,PPARA,PTGS1,SCAP,SLC25A12,SNCA,SREBF1,SRR,TWIST1 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1125 | 1037 | 75 | ABHD17A,ADAM10,ADIPOQ,AGR2,ANK3,APBB1,APPL1,ARRB1,B3GAT3,C1QTNF4,CARD10,CD200,CELSR2,CPTP,CROCC,EFNB2,ERBB4,FN1,FOXP1,GAS6,GJA1,GLI3,GOPC,GPD1L,GPLD1,HIF1A,HYAL2,IDH2,IRS1,ITGA3,ITGB1BP1,JUP,LDLRAP1,LGR4,LMNA,LPL,LRP5,MRAP2,MTCL1,MYH10,NLRP1,NLRP2,NPTN,NR1H4,PARD6A,PFKFB2,PKIA,PPP1R9B,PPP2R5A,PRKACA,PRKCA,PRKCH,PTCH1,PTPN14,RAB11FIP1,RAPGEF4,RASSF5,RGCC,ROCK2,SERGEF,SIRT3,SORL1,SPIDR,SREBF1,STK11,STXBP4,TCAF1,TIAM1,TM7SF3,TRIM6,TWIST1,UHMK1,UNC13B,WWP2,YWHAH |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 955 | 71 | ACAP3,ADAM10,ADIPOQ,APBB1,BCL11B,CDON,CRTC1,DISC1,DIXDC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,ERBB4,FBXW8,FN1,FZD1,FZD3,FZD4,GDF11,GDPD5,GLI2,GLI3,HIF1A,HMG20B,ID1,IDH2,ITGA3,ITGB1BP1,LIG4,LIMK1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,NIN,NPTN,NREP,PBX1,PLXND1,PPARA,PRAG1,PRKCH,PTK2B,RECK,RFLNB,ROBO2,ROCK2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SKI,SMARCD3,SORL1,SPOCK1,STK11,TENM3,TIAM1,TRAK2,TRIM58,YWHAH,ZNF365,ZSWIM5 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1125 | 1721 | 101 | ABCA3,ADCY1,ADCY9,ADIPOQ,ADRB2,AGRN,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,BBS2,BCHE,BCL9L,CASP9,CD9,CHRM3,CITED1,COL4A1,COL4A2,DUSP22,ENPP1,ERBB4,ESR1,FAM20C,FAT4,FBH1,FGF12,FGF5,FGFBP3,FGFRL1,FOXO1,FOXP1,FSTL3,FZD1,GAS2L1,GJA1,GNB5,GNRHR2,GPLD1,HTR1D,HTRA1,HYAL2,ID1,IGFBP7,IRS1,ITGA3,ITGB1BP1,JUP,KLF9,LGR4,LMO2,LPL,MAOB,MEN1,NPTN,NR1H4,NREP,PAPPA,PAQR8,PARD6A,PDE3B,PEG10,PPARA,PPP1R9B,PRKACA,PTCH1,PTK2B,ROBO2,ROCK2,RRAGA,SCAP,SESN3,SH3BP4,SKI,SKOR1,SLC9A3R1,SLX4,SMAD6,SMYD3,SNCA,SORL1,SORT1,SOST,SPIDR,SPINT2,SPRY3,SREBF1,STAT1,STK11,STXBP1,STXBP4,SULF1,SULT1A4,TGFBR2,UCN,UROS,VGF,YWHAH |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 0.0e+00 | 1125 | 1107 | 77 | ADAM10,ADIPOQ,ADORA1,APPL1,ATP7A,BBS2,BCR,CARD10,CAVIN1,CCDC125,CD200,CD9,DUSP22,EPB41L4B,ERBB4,EVL,FN1,FOXP1,FRMD5,GAS6,GJA1,GPLD1,HIF1A,HYAL2,IDH2,IQSEC1,ITGA3,ITGB1BP1,JCAD,JUP,KDR,KLRC4-KLRK1,LAMA1,LAMA5,LMNA,LPAR1,MAPRE2,MCAM,MIEN1,MINK1,PECAM1,PKP2,PLXND1,PRAG1,PRKCA,PRKX,PTK2B,PTPRM,RECK,RGCC,RHOBTB1,RNF207,ROCK2,SCARB1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SLC9A3R1,SORL1,SPINT2,SRGAP1,SULF1,SYNJ2BP,TCAF1,TGFBR2,TIAM1,TNFSF14,TRIM58,TWIST1,VCL,VSIR,WNT11,ZP3,ZSWIM5 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 1125 | 1454 | 90 | ADCY1,ADCY9,ADIPOQ,ADRB2,AGRN,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,BBS2,BCL9L,CASP9,CHRM3,CITED1,COL4A1,COL4A2,DUSP22,ENPP1,ERBB4,ESR1,FAM20C,FAT4,FBH1,FGF12,FGF5,FGFBP3,FGFRL1,FOXO1,FOXP1,FSTL3,FZD1,GAS2L1,GJA1,GNB5,GNRHR2,GPLD1,HTR1D,HTRA1,HYAL2,ID1,IGFBP7,IRS1,ITGA3,ITGB1BP1,JUP,KLF9,LGR4,LMO2,LPL,MEN1,NPTN,NR1H4,NREP,PAQR8,PARD6A,PDE3B,PEG10,PPARA,PPP1R9B,PRKACA,ROBO2,ROCK2,RRAGA,SESN3,SH3BP4,SKI,SKOR1,SLC9A3R1,SLX4,SMAD6,SMYD3,SNCA,SORL1,SORT1,SOST,SPIDR,SPINT2,SPRY3,SREBF1,STAT1,STK11,STXBP4,SULF1,SULT1A4,TGFBR2,UROS,YWHAH |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1125 | 1863 | 105 | ADIPOQ,ADORA1,ADRB2,AGO1,ARHGAP24,ARHGAP28,ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,ARRB2,BCR,BDKRB2,C12orf66,C1QTNF4,CARD10,CCDC125,CDON,CHRNA9,CYTH3,DEPDC7,DUSP22,EPHA7,ERBB4,ESR1,F2RL2,FBH1,FGF5,FN1,FOXO1,FZD4,GAS6,GDF11,GJA1,GPD1L,HEG1,HIF1A,HIP1,HYAL2,ID1,IL18,IQSEC1,IRS1,ITGA3,ITGB1BP1,JCAD,KDR,LPAR1,MAGI3,MAP3K13,MAP3K5,MAP4K2,MAPRE2,MCF2,MEIS3,MEN1,MINK1,MRAP2,MYORG,NPTN,NR1H4,PDE3B,PRAG1,PRKACA,PRKCA,PSD3,PTK2B,PTPN13,RALGAPA2,RASA4,RHOBTB1,ROCK2,RRAGA,RTN4R,S100A4,SEMA5A,SESN3,SGMS1,SH3BP4,SH3RF3,SHC2,SIPA1L2,SIRT3,SLC9A3R1,SORL1,SPRY3,SRGAP1,STAT1,STK11,STK38,STMN3,SYNJ2BP,TAOK2,TIAM1,TNFAIP8L1,TNFRSF11A,TNFSF14,TPD52L1,TRIM44,TSPAN6,TWIST1,UACA,UCN,VAV3,WNT11 |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1125 | 725 | 59 | ADIPOQ,ADORA1,ADRB2,AGR2,ANKS1A,AP2A2,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,BCR,BDKRB2,COL4A1,COL4A2,EFNB2,ENPP1,EPHA7,EPHB6,ERBB4,FAM20C,FAM83A,FAT4,FGF12,FGF5,FGFBP3,FGFRL1,FOXO1,FZD4,GPLD1,HIF1A,HIP1,IRS1,JCAD,KDR,MVP,MYORG,NPTN,NR1H4,NRTN,PRKCA,PTK2B,ROCK2,SESN3,SHC2,SLA,SLC9A3R1,SLC9A6,SNCA,SORL1,SORT1,SPRY3,SREBF1,STXBP4,SULF1,TIAM1,TNK2,VAV3,ZFYVE28 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 1125 | 1869 | 104 | ACPP,ADCY1,ADIPOQ,ADORA1,ADRB2,AGO1,AGR2,ARRB1,ARRB2,BVES,C1QTNF4,CARD10,CDON,CITED1,CRADD,CRTC1,DISC1,DIXDC1,DLG4,DUSP22,ERBB4,ESR1,F2RL2,FBH1,FGF5,FGFBP3,FOXP1,FZD4,GAS6,GDF11,GJA1,GPLD1,HIF1A,HIP1,HYAL2,IL18,IRS1,ITGB1BP1,JAG2,JCAD,JUP,KDR,KLF14,LDLRAP1,LFNG,LGR4,LPAR1,LYPD6,MAP3K13,MAP3K5,MAP4K2,MAPRE2,MEIS3,MEN1,MINK1,MPP2,MPP7,MRAP2,MYORG,NPTN,NR1H4,PECAM1,PFKFB2,POGLUT1,PRAG1,PRKCA,PRKCH,PTK2B,RECK,RNF207,ROBO2,ROCK2,RRAGA,RTN4R,S100A4,SARM1,SEMA5A,SH3RF3,SHC2,SIRT3,SKI,SLA,SLC9A3R1,SNAP47,SNCA,SORL1,STK11,STXBP1,SULF1,TAOK2,TIAM1,TM7SF3,TMOD2,TNFRSF11A,TNFSF14,TPD52L1,TRIM44,TRIM6,TSPAN6,UCN,UNC13B,VAV3,WNT11,YWHAH |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1125 | 1698 | 97 | ADCY1,ADCY9,ADH4,ADIPOQ,ADRB2,AGRN,APPL1,ARRB1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,BCHE,BCR,CASP9,CCS,CD9,CHRM3,CITED1,COL4A1,DGAT2,ENPP1,ESR1,FOXO1,FOXP1,FZD4,GAS6,GJA1,GLRB,GNB5,GNG12,GNRHR2,GPLD1,HIF1A,HLCS,HTR1D,HYAL2,ID1,IGFBP7,IL18,IRS1,JUP,KLF9,KLRC4-KLRK1,LOXL1,LPAR1,LPL,LRP11,LRP5,MAOB,MAP3K5,MEN1,MTHFR,NLRP1,NR1H4,P2RX1,PDE3B,PFKFB2,PMVK,PPARA,PPP1R9B,PRKACA,PRKCA,PTCH1,PTK2B,RGS19,ROCK2,RRAGA,SARM1,SCAP,SCARB1,SESN3,SGMS1,SH3BP4,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SORT1,SPIDR,SREBF1,SRR,STAT1,STXBP1,STXBP4,SULT1A4,TGFBR2,TIAM1,TNFRSF11A,TRIM6,UCN,UNC13B,VGF,WNT11 |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 766 | 60 | ABLIM2,ACTBL2,ADORA1,ANTXR1,ARHGAP28,ARHGEF19,ARRB1,ASAP3,BCR,CAPZA2,CDC42BPG,CDC42EP3,CSRP1,CXADR,DIXDC1,EPB41L4B,EVL,FAT1,FGF12,FHDC1,FRMD5,GBA2,GJA1,GJC1,GPD1L,GRHL3,HIP1,ID1,IQGAP2,IQSEC1,ITGB1BP1,JUP,LIMK1,LLGL1,LLGL2,LPAR1,MARCKS,MICAL3,MINK1,MYH10,PICK1,PKP2,PPM1E,PPP1R9B,PTK2B,RFLNB,RGCC,RHOBTB1,RNF207,ROCK2,SCN1B,SEMA5A,SLC9A3R1,SPIRE2,SSH2,TAOK2,THSD7A,TMOD2,WNT11,XIRP2 |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1125 | 1625 | 94 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,ARRB2,ATP7A,ATPSCKMT,BDKRB2,BRAT1,CAMK2N2,CARD10,CCNJL,CCNYL1,CDON,CHRNA9,DLG3,DLG4,DUSP22,EIF2AK1,ENPP1,EPHA7,ERBB4,FBH1,FN1,FOXO1,FZD1,FZD4,GAS6,GDF11,GPD1L,HEG1,HIF1A,HSPA2,HYAL2,ID1,IL18,INKA2,IRS1,ITGB1BP1,JCAD,KDR,LPAR1,LRP5,MAGI3,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,MVP,NPTN,NUP210,PARD6A,PECAM1,PFKFB2,PKIA,PPARA,PPM1E,PPP1R9B,PPP2R5A,PRKACA,PRKCA,PTK2B,PTPN13,RGCC,ROCK2,SH3RF3,SHC2,SIRT3,SLC25A23,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,STK11,STK38,SYNJ2BP,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TNK2,TPD52L1,TRIM6,TWIST1,UCN,VAV3,WDR91,WNT11,ZFYVE28 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 1029 | 71 | ADAM10,ADCY9,ADIPOQ,ATP7A,BASP1,BCR,CCM2,CDON,CHRNA9,CITED1,COL4A2,CXXC4,ERBB4,ERCC2,ETNK2,FBXW8,FN1,FZD1,FZD3,GJA1,GJB5,GLI2,GLI3,GRHL3,HEG1,HIF1A,HOXD8,IRX2,ITGA3,ITPK1,JAG2,KDR,LAMA1,LAMA5,LFNG,LHFPL5,LIG4,LMBR1,LRP5,LUZP1,MTHFR,MYH10,NAGLU,PBX1,PDZD7,PICK1,PLCD3,POGLUT1,PRICKLE1,PRKACA,PTCH1,RECK,RNF207,ROCK2,SEMA3F,SKI,SLC9A3R1,SMAD6,SOX18,SPINT2,SSBP3,STMN3,SULF1,TANC2,TENT5C,TFAP2A,TGFBR2,TWIST1,WNT11,ZFP14,ZP3 |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 1335 | 83 | ABLIM1,ABLIM2,ACTBL2,AGRN,ANK3,ANTXR1,ARHGAP28,ARHGEF19,ARMC2,ARRB1,ASAP3,BBS2,BCR,CAPZA2,CCDC68,CDC14B,CDC42BPG,CDC42EP3,CEP68,CFAP44,CROCC,CSRP1,CXADR,DISC1,DIXDC1,EPB41L4B,EVL,FAT1,FHDC1,FITM2,FRMD5,GAS2L1,GBA2,GFAP,GJA1,GRHL3,HIP1,ID1,IQGAP2,IQSEC1,ITGB1BP1,JUP,KATNAL2,KIF3A,LAMA5,LIMK1,LLGL1,LLGL2,LMNA,LPAR1,MAP10,MAPRE2,MARCKS,MAST3,MICAL3,MINK1,MTCL1,MYH10,NIN,PARD6A,PICK1,PKP2,PPM1E,PPP1R9B,PTK2B,RFLNB,RGCC,RHOBTB1,ROCK2,SEMA5A,SLC9A3R1,SNCA,SPIRE2,SSH2,STMN3,SUN1,TAOK2,THSD7A,TMOD2,TTLL1,TUBG2,WNT11,XIRP2 |
| GO_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 659 | 55 | ACAP3,ADAM10,APBB1,BCL11B,CDON,CRTC1,DISC1,DIXDC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,FBXW8,FN1,FZD1,FZD4,GDF11,GDPD5,GLI2,GLI3,HMG20B,ID1,ITGA3,LIMK1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,NIN,NPTN,NREP,PBX1,PLXND1,PRAG1,PTK2B,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SPOCK1,STK11,TENM3,TIAM1,TRAK2,YWHAH,ZNF365,ZSWIM5 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1880 | 103 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARPP19,ARRB1,ARRB2,ATG10,B3GAT3,BDKRB2,BRAT1,C6orf89,CAMK2N2,CARD10,CCNJL,CCNYL1,CDC14B,CDON,CHRNA9,DLG3,DLG4,DUSP22,EIF2AK1,ELFN2,ENPP1,EPHA7,ERBB4,FBH1,FN1,FOXO1,FZD1,FZD4,GAS6,GDF11,GPD1L,HEG1,HINT2,HMG20B,HSPA2,HYAL2,ID1,IL18,INKA2,ITGB1BP1,JARID2,JCAD,KDR,LIMK1,LMNA,LPAR1,LRP5,MAGI3,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,MTHFR,MVP,NPTN,NSMCE3,PARD6A,PECAM1,PHACTR2,PKIA,PPM1E,PPP1R9B,PPP2R5A,PRICKLE1,PRKACA,PRKCA,PTK2B,PTPN13,RASSF5,RGCC,ROCK2,SH3RF3,SHC2,SIRT3,SKI,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,SREBF1,STK11,STK38,SYNJ2BP,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TNK2,TPD52L1,TRIM44,TRIM6,TWIST1,UCN,WNT11,ZFYVE28 |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1160 | 76 | ABCD3,ADRB2,ANK3,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,ATP8B1,ATPSCKMT,CHRNA9,CHRNE,CLCN2,CLDN16,CYB5A,DLG3,DLG4,FGF12,GAS6,GJA1,GJC1,GLRB,GNB5,GOPC,GPD1L,HSPA2,KCNJ1,LRRC7,LRRC8B,MFSD3,MINK1,MPC1,MRS2,MT-CO2,P2RX1,PLCB2,PLCD3,PRAF2,PRKACA,PTK2B,RNF207,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC16A12,SLC25A12,SLC25A18,SLC25A23,SLC25A29,SLC25A42,SLC30A4,SLC35A1,SLC36A1,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SPG7,STIM2,SURF1,TCAF1,TMEM175,TMEM37,TMEM63C,TPCN1,TTYH3,TWIST1,WWP2,YWHAH |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 710 | 57 | ABCD2,ABCD3,ACP6,ACSM2B,ADIPOQ,ALDH3A2,AMACR,ASAH2,B3GALT1,BCO1,CDS1,CHKA,CLCN2,CRPPA,CYP2R1,DGAT2,ELOVL6,ERLIN2,ETNK2,FADS3,FITM2,GPD1L,GPLD1,HINT2,HSD17B8,IGFBP7,INPP4A,LPCAT3,LPCAT4,LPL,MECR,MLYCD,NR1H4,P2RX1,PBX1,PCTP,PEX7,PIGM,PIGN,PIGX,PLA2G12A,PLAAT3,PLPP6,PMVK,PTGS1,PTPN13,RAB4A,SCAP,SCARB1,SGMS1,SIRT3,SLC44A1,SPTLC3,SREBF1,ST6GALNAC3,TM7SF2,ZP3 |
| GO_LIPID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 328 | 38 | ABCD2,ABCD3,ADIPOQ,ADORA1,AIG1,ALDH3A2,AMACR,ASAH2,BCO1,BCO2,CRAT,CROT,ETFDH,GBA2,GDE1,GM2A,GPLD1,HINT2,IRS1,LIPE,LPL,MECR,MLYCD,MMAA,NUDT7,PDE3B,PEX2,PEX7,PLA2G12A,PLA2G2C,PLAAT3,PLCB2,PLCD3,PPARA,SCARB1,SORL1,TWIST1,YWHAH |
| GO_AXON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 523 | 48 | ADCY1,AGRN,ANK3,APBB1,BCL11B,CRPPA,DISC1,EFNB2,EPHA7,EVL,FN1,FZD3,GLI2,GLI3,KIF3A,LAMA1,LIMK1,LLGL1,MAP3K13,MCF2,METRN,MYH10,NIN,NPTN,NREP,NRTN,PLXND1,PRKCA,PTCH1,PTPRM,RAB3A,ROBO2,RTN4R,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A6,SPRY3,STK11,STXBP1,TAOK2,TIAM1,TRAK2,VCL,ZSWIM5 |
| GO_CHEMICAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1125 | 1207 | 77 | ADCY1,ADCY9,ADIPOQ,ADORA1,ANK3,ARRB1,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,BDKRB2,CHRNA9,CLDN16,CLN5,DGAT2,DISC1,DLG4,DMXL2,EIF2AK1,ENPP1,ESR1,F2RL2,FGF12,FITM2,FOXO1,GAS6,GJA1,GPD1L,GPLD1,GPR157,GRHL3,HIF1A,HYAL2,IL18,IRS1,KDR,LDLRAP1,LPAR1,LPL,LRP5,MEN1,NPTN,NR1H4,P2RX1,PLCB2,PLCD3,PRKACA,PTCH1,PTK2B,SCARB1,SCN1B,SCNN1A,SCNN1G,SESN3,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SNX10,STAT1,STIM2,STK11,STXBP4,TIAM1,TMEM175,TMTC2,TPCN1,UNC13B,VGF |
| GO_CELL_JUNCTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 293 | 35 | BCR,CCM2,CD9,CDH12,CDH17,CDH18,CDH7,CDH8,CLDN9,CXADR,DUSP22,FN1,GJA1,GJC1,HEG1,IQSEC1,ITGB1BP1,JUP,KDR,LAMA5,MAPRE2,MPP7,NR1H4,PARD6A,PECAM1,PKP2,PRKACA,PRKCA,PRKCH,PTK2B,ROCK2,TAOK2,VCL,WNT11,XIRP2 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1125 | 1258 | 78 | ADIPOQ,ADORA1,ANTKMT,APBB1,ARRB1,ARRB2,ASH2L,ATP7A,ATPSCKMT,BDKRB2,CDC42BPG,DLG3,DLG4,DPF1,DPY19L1,DPY19L3,DUSP22,EPHA7,EPHB6,ERBB4,FKBP7,GALNT1,GALNT11,GALNT2,GAS6,GGCX,GPD1L,HIF1AN,HINT2,HMG20B,HYAL2,IL18,IRF4,JARID2,KDR,LMNA,LOXL1,MAP3K13,MAST3,MEN1,MGAT5B,MOCS3,MVP,NR1H4,NUP210,PECAM1,PIN4,POGLUT1,POGLUT3,PPIC,PRKACA,PRKCA,PRKCH,PRKX,PTK2B,RAB3D,RNF212,ROCK2,SGK1,SIRT3,SLA,SMYD3,SNCA,STK32A,STK38,TGFBR2,TNK2,TRIM6,TTLL1,TTLL13P,TWIST1,UCN,UHMK1,ZDHHC14,ZDHHC20,ZDHHC24,ZFYVE28,ZMIZ2 |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1125 | 1235 | 77 | ACTR5,ADIPOQ,ADORA1,ADRB1,ADRB2,ARRB1,ARRB2,ATP7A,BDKRB2,BRAT1,CASP9,CD9,CDH8,CDS1,CHRNA9,CRADD,CRTC1,CYP2R1,DDAH1,DISC1,ERCC2,ERCC4,FOXO1,FZD3,GJA1,GMPR,GPLD1,H2AW,HABP4,HIF1A,HIF1AN,HSPA2,HYAL2,IGFBP7,JUP,LHFPL5,LIG4,LMNA,LPAR1,LPL,LRP11,MEN1,MT-CO2,MTHFR,NPTN,NSMCE3,NUP210,PDZD7,PICK1,PPARA,PPEF1,PRKACA,PTCH1,PTK2B,RAB3A,RAG1,REEP6,RGCC,ROCK2,SCAP,SERPINB13,SLC12A5,SLC25A23,SOST,SPIDR,STAT1,STK11,SUN1,TANC1,TGFBR2,TNFRSF11A,TNFSF14,TWIST1,UCN,USP2,VGF,WNT11 |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 1125 | 1061 | 70 | ABCA3,ABCD3,ADAM10,ADCY1,ADIPOQ,AGRN,ARRB1,ARRB2,ATP8B1,BCHE,CASP9,CHKA,CHRM3,CHRNE,CYP2R1,CYP2U1,FOXO1,FZD1,FZD3,FZD4,GAS6,GJA1,GNB5,GPLD1,HLCS,HTR1D,ID1,IGFBP7,IPCEF1,ITGA3,JUP,KDR,KLF9,LPL,MAOB,MAP3K5,MTHFR,NLRP1,NSMCE3,P2RX1,PPARA,PPM1E,PPP1R9B,PRAF2,PTCH1,PTK2B,PTPRM,RGS19,ROCK2,SLC12A5,SLC16A12,SLC25A12,SLC25A18,SLC25A23,SLC25A29,SLC25A42,SLC36A1,SLC46A1,SLC9A3R1,SMYD3,SNCA,SPIDR,SREBF1,SRR,STAT1,SULT1A4,TGFBR2,TIAM1,TRDMT1,VAV3 |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1428 | 84 | ADIPOQ,ADRB2,AGR2,AGRN,APBB1,ARRB2,BASP1,BBS2,BCL9L,CDON,CRTC1,CTNNBIP1,DDAH1,DISC1,DLG4,EFNB2,ENC1,ERBB4,FAM20C,FBXW8,FN1,FZD1,FZD3,FZD4,GAS6,GDPD5,GJA1,GLI2,GLI3,HIF1A,HIF1AN,HMG20B,HSPB6,IL18,ITGA3,JCAD,JUP,KDR,LGR4,LIG4,LIMK1,LMNA,LPAR1,LPL,LRP5,LRRC7,MAP3K13,MAP3K5,METRN,MRTFB,NIN,NPTN,NR1H4,ODAPH,PLXND1,PRKCA,PRKCH,PTCH1,PTK2B,RAB7B,RAG1,RGCC,ROBO2,SCN1B,SEMA5A,SERPINI1,SLC25A12,SMARCD3,SORL1,SSBP3,STAT1,STK11,TENM3,TFAP2A,TGFBR2,THBS2,TIAM1,TNFSF14,TRIM58,TWIST1,VSIR,ZHX3,ZNF365,ZP3 |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1125 | 847 | 61 | ADIPOQ,ANK3,BVES,CD200,CD9,CDH12,CDH17,CDH18,CDH7,CDH8,CELSR2,CLDN11,CLDN16,CLDN9,CSRP1,CXADR,DENND6A,DLG3,DLG4,DUSP22,EFNB2,EPHA7,FAT1,FAT4,FGFRL1,FSTL3,GAS6,GLI2,GLI3,IL18,JUP,KLRC4-KLRK1,LAMA5,LRFN3,LRRC7,MINK1,NPTN,PCDH17,PCDH18,PCDH7,PCDHA3,PCDHB2,PCDHGB4,PECAM1,PKP2,PODXL2,PPARA,PRKCA,PTPRM,RAG1,RGCC,ROBO2,SPINT2,STXBP1,SYNJ2BP,TENM3,TGFBR2,TNFSF14,VCL,VSIR,ZP3 |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 1125 | 622 | 51 | ADORA1,ADRB2,AGO1,AP2A2,ARHGEF19,ARRB2,BCL9L,CELSR2,CHRNA9,CHRNE,CITED1,CMAHP,CTNNBIP1,CXXC4,DISC1,DIXDC1,DLG4,ESR1,FOXO1,FZD1,FZD3,FZD4,GLI2,GLI3,GLRB,GRHL3,ITGA3,JUP,LGR4,LRP5,LYPD6,MPP2,P2RX1,PARD6A,PLCB2,PRICKLE1,PRICKLE2,PTK2B,RECK,SEMA5A,SKI,SLC9A3R1,SNCA,SOST,STK11,SULF1,TIAM1,TNRC6C,UNC13B,VANGL1,WNT11 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 1125 | 625 | 51 | ABHD17A,ADAM10,ADIPOQ,ADORA1,AGR2,AGRN,ANK3,APPL1,ARL3,BBS2,DLG3,DLG4,EFR3A,GAS6,GGA3,GLRB,GOPC,GPHN,ITGA3,ITGB1BP1,JUP,LAMA5,LDLRAP1,LRRC7,MRAP2,MTCL1,PACS2,PICK1,PKP2,PPP1R9B,PPP2R5A,PRKCH,PTCH1,RAB26,RAB3A,RAB3D,REEP2,ROCK2,SLC9A3R1,SNAP47,STXBP1,SYNJ2BP,TAOK2,TCAF1,TIAM1,TRAM1L1,TRAM2,YWHAH,ZDHHC14,ZDHHC20,ZDHHC24 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1125 | 1782 | 96 | ACPP,ADAM10,ADIPOQ,ADRB2,AGO1,ALDH5A1,ARHGAP28,ASH2L,ATF7IP,ATP5F1D,BBS10,BCL9L,BRF1,CAPZA2,CARD10,CDC42EP3,CDH17,COX16,CPTP,CRTC1,CTNNBIP1,DLG4,ERCC2,ERCC4,ESR1,EVL,F8,FGFRL1,FN1,GBA2,GEMIN8,GFAP,GJA1,GLRB,GOPC,H1-0,H2BC4,H3C10,H3C12,H4C9,HIP1,HLA-DMA,HSD17B8,IMMP2L,IQGAP2,ITGB1BP1,JUP,KHDRBS3,LLGL1,MARCKS,MAT2A,MEN1,MPP2,MPP7,NAP1L3,NAP1L5,NDUFB3,NIN,NLRP1,P2RX1,PET100,PICK1,PRKACA,PTK2B,RAB3A,RASEF,SKI,SLC9A3R1,SMAD6,SMYD3,SNAP47,SNCA,SORL1,SOST,SPIDR,SPIRE2,SRR,SSBP3,STXBP1,SURF1,TIAM1,TMEM120B,TMOD2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9,TRIM34,TRIM6,TSPYL1,TTC19,TUBG2,UNC13B,UXS1,VPS18,ZDHHC8 |
| GO_FATTY_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 380 | 39 | AASDH,ABCD2,ABCD3,ACADSB,ACSM2B,ADH4,ADIPOQ,AIG1,ALDH3A2,ALDH5A1,AMACR,ASAH2,CRAT,CROT,CRYL1,CYP2U1,CYP4V2,DGAT2,ECHDC3,ELOVL6,ERLIN2,ETFDH,FADS3,HSD17B8,IRS1,LIPE,LPL,MECR,MLYCD,MMAA,NUDT7,PEX2,PEX7,PPARA,PTGS1,SCAP,SNCA,SREBF1,TWIST1 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 440 | 42 | ABCD2,ABCD3,ACADSB,ADH4,ADIPOQ,AIG1,ALDH3A2,ALDH4A1,ALDH5A1,ALDH7A1,AMACR,BCKDHB,CEMIP2,CRAT,CROT,CRYL1,CSAD,DDAH1,ENTPD8,ETFDH,HYAL2,IRS1,LIPE,LRP5,MECR,MLYCD,MMAA,NT5M,NUDT16,NUDT18,NUDT7,PCYOX1L,PEX2,PEX7,PFKFB2,PPARA,SCARB1,SLC25A12,SULT1A4,TST,TWIST1,TYMP |
| GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 504 | 45 | ACAP3,ADAM10,APBB1,CRTC1,DISC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,FBXW8,FN1,FZD1,FZD4,ID1,ITGA3,LIMK1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,NIN,NPTN,PLXND1,PRAG1,PTK2B,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SPOCK1,STK11,TENM3,TIAM1,TRAK2,YWHAH,ZNF365,ZSWIM5 |
| GO_CELLULAR_LIPID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 212 | 29 | ABCD2,ABCD3,ADIPOQ,AIG1,ALDH3A2,AMACR,ASAH2,BCO1,BCO2,CRAT,CROT,ETFDH,GBA2,GDE1,GM2A,GPLD1,IRS1,LIPE,LPL,MECR,MLYCD,MMAA,NUDT7,PEX2,PEX7,PPARA,SCARB1,SORL1,TWIST1 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 995 | 66 | ADCY1,ALDH3A2,ALDH5A1,ARRB2,ATP7A,BASP1,BBS2,BCL11B,BCR,BTD,CD9,CDON,CELSR2,CITED1,CLN5,COL4A1,COQ8B,DISC1,DIXDC1,EPHA7,ERBB4,ERCC2,FAT4,FZD1,FZD3,FZD4,GBA2,GDF11,GDPD5,GLI2,GLI3,GNG12,GRHL3,HERC1,HIF1A,ID1,IMMP2L,JARID2,JRKL,LIG4,LPAR1,MAOB,MEN1,MYH10,NAGLU,NIN,PCDH18,PPP1R9B,PTCH1,ROBO2,RTN4R,SCN1B,SEMA3F,SEMA5A,SEMA6D,SERPINI1,SKI,SPOCK1,SRR,SSBP3,SUN1,TFAP2A,TGFBR2,TRAPPC9,YWHAH,ZNF365 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1470 | 84 | ADIPOQ,APBB1,ATF7IP,ATP8B1,BACH2,BASP1,BCDIN3D,CBX5,CBX6,CBX7,CCDC85B,CITED1,CTC1,CTNNBIP1,DPF1,DUSP22,ERCC4,ESR1,FAM220A,FBH1,FOXN3,FOXO1,FOXP1,FZD1,GAS6,GJA1,GLI2,GLI3,H1-0,H3C10,H3C12,H4C9,HIF1AN,HOXD8,HR,ID1,IRX2,JARID2,JAZF1,LGR4,MAGEF1,MEN1,MYPOP,NR1H4,NUDT16,NUPR2,PCBP3,PEX2,PKIA,PPARA,PRICKLE1,PTCH1,PURB,RADX,RUNX1T1,SATB1,SKI,SKOR1,SLX4,SNCA,SOX13,SOX18,SREBF1,STAT1,SUPT4H1,TCFL5,TENT5C,TFAP2A,THRAP3,TRIM6,TRIM66,TWIST1,USP2,WNT11,WWP2,ZBED6,ZBTB42,ZBTB45,ZHX3,ZKSCAN3,ZNF18,ZNF540,ZNF658,ZP3 |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 687 | 53 | ACAP3,ADAM10,AGRN,APBB1,ATP7A,ATP8B1,CDC42EP3,CROCC,CRTC1,DISC1,DLG4,DNM3,EFNB2,ENC1,EPHA7,EVI5L,EVL,FBXW8,FN1,FZD1,FZD4,ID1,ITGA3,LIMK1,LPAR1,LRRC7,MAP3K13,MCF2,METRN,MIEN1,NIN,NPTN,PLXND1,PRAG1,PTK2B,ROBO2,RTN4R,SARM1,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPINI1,SPOCK1,STK11,TENM3,TIAM1,TRAK2,YWHAH,ZNF365,ZSWIM5 |
| GO_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 477 | 43 | ACAP3,ADRB1,AGRN,ARHGAP24,ARHGAP28,ARHGEF19,ARRB1,ARRB2,ASAP3,BCR,BVES,CCDC125,CHML,ELMOD1,EVI5L,GNB5,GPSM1,GRHL3,IQGAP2,IQSEC1,ITGB1BP1,KLRC4-KLRK1,LLGL1,LLGL2,MAPRE2,PLXND1,PTK2B,RALGAPA2,RASA4,RINL,RTN4R,SH3BP4,SIPA1L2,SRGAP1,STMN3,TBC1D16,TBC1D2,TBC1D24,TBC1D8,TIAM1,TNK2,VAV3,WNT11 |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 767 | 56 | ACAP3,ADRB1,AGRN,ANTXR1,ARHGAP24,ARHGAP28,ARHGEF19,ARRB1,ASAP3,BCR,C6orf89,CASP9,CCDC125,CD200,CHML,CRADD,ELMOD1,ESR1,EVI5L,FN1,GM2A,GNB5,GPLD1,GRHL3,HIP1,HSPA2,IQSEC1,LLGL1,LLGL2,LPAR1,MAP3K5,MAPRE2,MTCL1,NLRP1,NLRP2,P2RX1,PLCB2,PTK2B,RAB3A,RAB4A,RALGAPA2,RASA4,RINL,ROCK2,RTN4R,SIPA1L2,SNCA,SRGAP1,TBC1D16,TBC1D2,TBC1D24,TBC1D8,TIAM1,VAV3,VSIR,WNT11 |
| GO_GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 341 | 36 | ALG1,ALG1L,ATP7A,B3GALT1,B3GAT3,B4GAT1,C1GALT1C1,C1GALT1C1L,CHST12,CHST7,CHSY3,COG7,CRPPA,DPY19L1,DPY19L3,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GLCE,GXYLT2,ITM2A,LFNG,MAN1A1,MGAT5B,MUC2,NDST3,POGLUT1,POGLUT3,SLC35C1,ST6GALNAC3,TMTC2,TMTC3,TRAK2,XYLT2 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 1220 | 74 | ADCK1,ADRB2,AGRN,APBB1,APPL1,ARRB1,ARRB2,ATF7IP,ATP7A,C6orf89,CDC42EP3,CDH17,CROCC,CRTC1,DISC1,DLG4,DNM3,ENC1,ERCC2,ERCC4,ESR1,EVL,FBXW8,FN1,FYCO1,FZD1,FZD4,HIF1A,HIP1,ID1,IQGAP2,IQSEC1,ITGA3,ITGB1BP1,JARID2,KDR,LDLRAP1,LIG4,LIMK1,LMNA,LPAR1,LRP5,LRRC7,MAP3K13,MAPRE2,METRN,MIEN1,MPP7,NIN,NPTN,PICK1,PLXND1,PPM1E,PTK2B,RGCC,ROBO2,ROCK2,SCN1B,SEMA5A,SERPINI1,SLX4,SNCA,SPIDR,SPIRE2,SREBF1,STK11,TENM3,THBS2,TIAM1,TNFSF14,TRIM58,UNC13B,WNT11,YWHAH |
| GO_CELL_CELL_JUNCTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 188 | 27 | CCM2,CD9,CDH12,CDH17,CDH18,CDH7,CDH8,CLDN9,CXADR,GJA1,GJC1,HEG1,IQSEC1,JUP,MAPRE2,MPP7,NR1H4,PARD6A,PECAM1,PKP2,PRKACA,PRKCA,PRKCH,ROCK2,VCL,WNT11,XIRP2 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 942 | 63 | AGRN,ANTXR1,ARHGAP28,ASAP3,ATF7IP,ATP7A,ATP8B1,BBS10,CAPZA2,CDC42EP3,CDH17,CPTP,CROCC,CTNNBIP1,DNM3,DUSP22,EPHA7,ERCC2,ERCC4,ESR1,EVI5L,EVL,FZD1,GBA2,GFAP,GJA1,HSPA2,ID1,IQGAP2,ITGB1BP1,KDR,LIMK1,LPAR1,LRFN3,MIEN1,MPP7,NBDY,NIN,NUDT16,PICK1,PPM1E,PRKACA,PRKCA,PRKCH,PTK2B,RAB3A,RGCC,ROBO2,ROCK2,SIRT3,SLX4,SMAD6,SNCA,SORL1,SOST,SPIDR,SPIRE2,STXBP1,THBS2,TMOD2,UNC13B,VPS18,WNT11 |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1125 | 569 | 47 | ARHGAP24,ARHGAP28,ARHGEF19,ARHGEF26,ARHGEF4,ARL3,ARRB1,BCR,CCDC125,CDC42EP3,CDON,CHML,CYTH3,DEPDC7,F2RL2,HEG1,IQSEC1,ITGA3,LIMK1,LPAR1,MAPRE2,MCF2,PECAM1,PRAG1,PSD3,RAB26,RAB3A,RAB3D,RAB4A,RAB7B,RALGAPA2,RAPGEF4,RASA4,RGL1,RGS19,RHOBTB1,ROCK2,RTN4R,SHC2,SIPA1L2,SPRY3,SRGAP1,STMN3,SYNJ2BP,TIAM1,TNK2,VAV3 |
| GO_EPITHELIAL_TUBE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 327 | 35 | CCM2,CITED1,COL4A1,CTNNBIP1,EFNB2,EPHA7,ESR1,FAT4,FOXP1,FZD1,FZD3,GLI2,GLI3,GRHL3,HIF1A,IRX2,LAMA1,LAMA5,LGR4,LRP5,LUZP1,MTHFR,PBX1,PLXND1,PRICKLE1,PRKACA,PRKX,PTCH1,RNF207,SKI,SOX18,SPINT2,TGFBR2,TWIST1,WNT11 |
| GO_BLOOD_VESSEL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 686 | 52 | AGO1,ARHGAP24,CARD10,CCM2,CEMIP2,CITED1,COL4A1,COL4A2,DDAH1,EFNB2,ENPEP,FN1,FZD4,GJC1,GPLD1,HEG1,HIF1A,HIF1AN,HSPB6,ID1,IL18,ITGB1BP1,JCAD,JUP,KDR,LAMA1,LAMA5,LRP5,MCAM,PDE3B,PECAM1,PLCD3,PLXND1,PRKCA,PRKX,PTK2B,PTPRM,RECK,RGCC,ROCK2,SEMA5A,SOX18,STAT1,SULF1,SYNJ2BP,TGFBR2,THBS2,THSD7A,TWIST1,TYMP,VAV3,WNT11 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 724 | 53 | ADCK1,ANTXR1,ARHGAP28,ARRB2,CAPZA2,CPTP,CTC1,CTNNBIP1,DLG4,DNM3,DUSP22,EFNB2,EPHA7,ERCC4,EVI5L,EVL,H1-0,HSPA2,ID1,IK,ITGA3,ITGB1BP1,JARID2,LMNA,LPAR1,MCF2,NBDY,PICK1,PRAG1,RGCC,ROBO2,ROCK2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SKI,SLX4,SMAD6,SNCA,SORL1,SOST,SPOCK1,STXBP1,TMEM14A,TMOD2,TRAK2,TWIST1,UCN,YWHAH,ZNF365 |
| GO_AMEBOIDAL_TYPE_CELL_MIGRATION | 0.0e+00 | 0.0e+00 | 1125 | 462 | 41 | APPL1,CARD10,EFNB2,EPB41L4B,ERBB4,EVL,FN1,FOXP1,GJA1,GPLD1,HIF1A,HYAL2,ID1,IQSEC1,ITGA3,ITGB1BP1,JCAD,JUP,KDR,LAMA5,MAPRE2,NRTN,PECAM1,PLXND1,PRKCA,PRKX,PTK2B,PTPRM,RGCC,ROCK2,SCARB1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SOX18,SYNJ2BP,TGFBR2,TWIST1,WNT11 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1125 | 802 | 56 | ABHD17A,ADAM10,ADIPOQ,AGR2,ANK3,APPL1,ARRB1,ATPSCKMT,B3GAT3,BVES,CARD10,CROCC,EFNB2,ERBB4,GAS6,GLI3,GOPC,GPD1L,GPLD1,HIF1A,HYAL2,ITGA3,ITGB1BP1,JUP,LDLRAP1,LMNA,LRP5,MRAP2,MTCL1,NPTN,NR1H4,PARD6A,PCDH17,PKIA,PPP1R9B,PPP2R5A,PRKACA,PRKCH,PTK2B,PTPN14,RASSF5,REEP2,REEP6,ROCK2,SNCA,SORL1,SPIDR,SREBF1,STK11,STXBP1,STXBP4,TCAF1,TIAM1,TRIM58,UHMK1,YWHAH |
| GO_ORGANIC_ACID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 271 | 31 | ABCD2,ABCD3,ACADSB,ADIPOQ,AIG1,ALDH3A2,ALDH4A1,ALDH5A1,ALDH7A1,AMACR,BCKDHB,CEMIP2,CRAT,CROT,CRYL1,CSAD,DDAH1,ETFDH,HYAL2,IRS1,LIPE,MECR,MLYCD,MMAA,NUDT7,PCYOX1L,PEX2,PEX7,PPARA,TST,TWIST1 |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1125 | 1174 | 70 | ADIPOQ,ADRB2,ANK3,ARHGAP28,ARPP19,ARRB1,ARRB2,ATP7A,CAMK2N2,CD200,COL28A1,CSRNP3,CTNNBIP1,DISC1,DLG3,DUSP22,ELFN2,ERCC4,ESR1,FBH1,FGF12,GAS6,GNB5,GOPC,GPSM1,HABP4,HEG1,HYAL2,ID1,INKA2,IQGAP2,ITGB1BP1,KLRC4-KLRK1,LIMK1,LRP5,LYPD6,MARF1,MEN1,MVP,NLRP2,NR1H4,PHACTR2,PKIA,PPARA,PPM1E,PPP1R9B,PPP2R5A,PTCH1,RAG1,RASA4,RECK,ROCK2,SERPINB13,SERPING1,SERPINI1,SH3BP4,SLC9A3R1,SMYD3,SNCA,SORL1,SORT1,SPINT2,SPOCK1,SPRY3,STK38,TNFSF14,TNK2,TWIST1,WWP2,ZFYVE28 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1125 | 767 | 54 | ADIPOQ,ANK3,APBB1,ARRB1,B3GAT3,C1QTNF4,CD200,CPTP,EFNB2,FN1,FOXP1,GAS6,GJA1,GLI3,GOPC,GPLD1,HIF1A,HYAL2,IDH2,IRS1,ITGB1BP1,JUP,LGR4,LPL,LRP5,MTCL1,MYH10,NLRP1,NLRP2,NR1H4,PARD6A,PFKFB2,PKIA,PRKACA,PRKCA,PTPN14,RAB11FIP1,RAPGEF4,RGCC,SERGEF,SIRT3,SORL1,SPIDR,SREBF1,STXBP4,TCAF1,TIAM1,TM7SF3,TRIM6,TWIST1,UHMK1,UNC13B,WWP2,YWHAH |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1151 | 69 | ADIPOQ,ADORA1,AMACR,ANK3,AP2A2,APPL1,ARL3,B3GAT3,BCR,CHML,COG7,COPG2,CRAT,CROT,EVI5L,GAS6,GGA3,GLI3,GSTK1,HYAL2,IFT81,IMMP2L,ITGB1BP1,JUP,KIF3A,LMNA,LRRC7,MLYCD,MTCL1,NUDT7,NUP210,NXF3,PEX1,PEX2,PEX7,PICK1,PKIA,PRICKLE1,PRKACA,PTPN14,RAB26,RAB3A,RAB3D,RAB4A,RAB7B,RANBP6,REEP2,SNX1,SORCS2,SORL1,SREBF1,STX17,STXBP4,SYNJ2BP,TAOK2,TBC1D16,TBC1D2,TBC1D8,TCAF1,TRAK2,TRAM1L1,TRAM2,UHMK1,UNC93B1,VPS18,YWHAH,ZDHHC14,ZDHHC20,ZDHHC24 |
| GO_GLYCOPROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 412 | 38 | ALG1,ALG1L,ATP7A,B3GALT1,B3GAT3,B4GAT1,C1GALT1C1,C1GALT1C1L,CHST12,CHST7,CHSY3,COG7,CRPPA,DPY19L1,DPY19L3,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GLCE,GXYLT2,HIF1A,ITM2A,LFNG,MAN1A1,MGAT5B,MUC2,NDST3,POGLUT1,POGLUT3,SLC35C1,ST6GALNAC3,SULF1,TMTC2,TMTC3,TRAK2,XYLT2 |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 372 | 36 | ACPP,ACSM2B,ALDH5A1,B4GAT1,BPNT1,BTD,CHST12,CHST2,CHST7,CHSY3,CSAD,DGAT2,ELOVL6,ENPP1,FAR2,GLCE,GSTA4,GSTK1,HLCS,HSD17B8,MAT2A,MAT2B,MLYCD,MPC1,MRI1,MTHFR,NDST3,NUDT7,PAPSS1,PCYOX1L,PMVK,SNCA,SULT1A4,SUOX,TST,XYLT2 |
| GO_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 1180 | 70 | ADORA1,ADRB2,ANK3,ARRB2,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,ATPSCKMT,CCS,CHRNA9,CHRNE,CLDN16,COMMD3,CYB5A,DLG3,DLG4,FGF12,GAS6,GJA1,GNB5,GPD1L,HSPA2,KCNJ1,LRRC7,MAOB,MFSD3,MINK1,MRS2,MT-CO2,P2RX1,PKP2,PLCB2,PLCD3,PRKACA,PTK2B,RNF207,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC22A18,SLC25A23,SLC25A29,SLC25A42,SLC30A4,SLC36A1,SLC44A1,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SPG7,STIM2,SURF1,TMEM175,TMEM37,TMEM63C,TPCN1,TWIST1,UCN,WWP2,YWHAH |
| GO_CELL_JUNCTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1125 | 244 | 29 | BCR,CD9,CDH12,CDH17,CDH18,CDH7,CDH8,DUSP22,FN1,GJA1,GJC1,HEG1,ITGB1BP1,JUP,KDR,LAMA5,MPP7,NR1H4,PARD6A,PECAM1,PKP2,PRKACA,PRKCA,PRKCH,PTK2B,ROCK2,TAOK2,VCL,WNT11 |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 1000 | 63 | ADIPOQ,APBB1,ARRB2,BCL9L,CDON,CRTC1,CTNNBIP1,DISC1,DLG4,EFNB2,ENC1,FAM20C,FBXW8,FN1,FZD1,FZD3,FZD4,GAS6,GDPD5,GJA1,GLI2,GLI3,HIF1A,HIF1AN,HMG20B,IL18,ITGA3,KDR,LIG4,LIMK1,LPAR1,LPL,LRP5,LRRC7,MAP3K13,MAP3K5,METRN,NIN,NPTN,PLXND1,PRKCA,PRKCH,PTCH1,PTK2B,RAB7B,RAG1,RGCC,ROBO2,SCN1B,SEMA5A,SERPINI1,SMARCD3,STAT1,STK11,TENM3,TGFBR2,TIAM1,TNFSF14,TRIM58,TWIST1,VSIR,ZHX3,ZNF365 |
| GO_REGULATION_OF_SECRETION | 0.0e+00 | 0.0e+00 | 1125 | 824 | 56 | ADCY1,ADIPOQ,ADORA1,APBB1,ARRB1,BCR,C1QTNF4,CD200,CPTP,FN1,FOXP1,GAS6,GJA1,GPLD1,HIF1A,HYAL2,IDH2,IRS1,LGR4,LPL,LRP5,MAOB,MYH10,NLRP1,NLRP2,NR1H4,P2RX1,PARD6A,PFKFB2,PRKCA,RAB11FIP1,RAB26,RAB3A,RAB3D,RAPGEF4,RGCC,SEPTIN1,SEPTIN5,SERGEF,SGK1,SIRT3,SLC9A3R1,SNCA,SORL1,SREBF1,STXBP1,STXBP4,TIAM1,TM7SF3,TNFRSF11A,TRIM6,TWIST1,UCN,UNC13B,VPS18,ZP3 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1988 | 98 | ABCD2,ADRB2,AGO1,AGRN,APBB1,APPL1,ARPP19,ARRB1,ARRB2,ASH2L,ATF7IP,BCL11B,BCL9L,BEX1,BRF1,CDON,CITED1,CRTC1,CSRNP3,CTC1,DBP,DDAH1,DGAT2,DPF1,ERBB4,ERCC2,ERLIN2,ESR1,FOXO1,FSTL3,FZD1,FZD4,GLI2,GLI3,GPLD1,GRHL3,H1-0,HABP4,HELZ2,HIF1A,HLF,HOXD8,HYAL2,IL18,IRF4,IRS1,ITGB1BP1,JUP,KLF14,KLRC4-KLRK1,LGR4,LMO2,LRP5,MAP3K5,MEIS3,MEN1,MRTFB,MT-CO2,MYRFL,NR1H4,PARM1,PBX1,PLXND1,PPARA,PTCH1,PTK2B,RGCC,SCAP,SCARB1,SIRT3,SKI,SLC25A12,SMAD6,SMARCD3,SMYD3,SNCA,SOST,SOX13,SOX18,SREBF1,SSBP3,STAT1,SUPT4H1,TFAP2A,THRAP3,TOX2,TRIM44,TWIST1,UCN,UHMK1,WNT11,WWP2,YWHAH,ZBTB48,ZKSCAN3,ZMIZ2,ZNF287,ZP3 |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 594 | 46 | ACP6,ADCY1,ADCY9,ATP5F1D,ATPSCKMT,CDS1,CHKA,CKMT1A,CKMT1B,CRYL1,ELOVL6,ENTPD8,ETNK2,FITM2,GPD1L,GPHN,HSD17B8,IDH2,INPP4A,LHPP,LPCAT3,LPCAT4,MLYCD,MOCS1,MOCS3,MPC1,MT-CO2,NR1H4,PAPSS1,PCTP,PIGM,PIGN,PIGX,PLA2G12A,PLAAT3,PLCB2,PLCD3,PMVK,PTK2B,PTPN13,RAB4A,SGMS1,SLC25A12,SLC44A1,SNCA,ZP3 |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 984 | 62 | ADIPOQ,ADORA1,ADRB2,ANK3,APBB1,APPL1,ARPP19,ARRB1,ARRB2,ATPSCKMT,B3GAT3,BCR,C1QTNF4,DNM3,FGF12,GAS6,GJA1,GLI3,GPD1L,GPLD1,HIF1A,HIP1,HSPA2,HYAL2,IRS1,ITGB1BP1,JUP,LDLRAP1,LPL,MTCL1,MYH10,NLRP1,NLRP2,NR1H4,P2RX1,PARD6A,PFKFB2,PICK1,PKP2,PRKACA,PTCH1,RAB3A,RAB3D,RGCC,RNF207,SCN1B,SGK1,SIRT3,SLC9A3R1,SNCA,SORL1,STIM2,STXBP1,TCAF1,TM7SF3,TNFRSF11A,TRIM6,TWIST1,UCN,UNC13B,YWHAH,ZP3 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1673 | 87 | ABCD2,ADIPOQ,AGO1,APBB1,ATF7IP,ATP8B1,BACH2,BASP1,CBX5,CBX6,CBX7,CCDC85B,CITED1,CTC1,CTNNBIP1,DPF1,DUSP22,EIF2AK1,ENC1,ENPP1,ERLIN2,ESR1,FAM220A,FBH1,FOXN3,FOXO1,FOXP1,FZD1,GAS6,GJA1,GLI2,GLI3,H1-0,H3C10,H3C12,H4C9,HIF1AN,HOXD8,HR,ID1,IRX2,ITM2A,JARID2,JAZF1,LGR4,MEN1,MYPOP,NR1H4,NUPR2,PAIP2B,PCBP3,PEX2,PKIA,PPARA,PRICKLE1,PTCH1,PURB,ROCK2,RUNX1T1,SATB1,SCAP,SKI,SKOR1,SNCA,SOX13,SOX18,SREBF1,STAT1,SUPT4H1,TCFL5,TFAP2A,TNRC6C,TRIM6,TRIM66,TWIST1,USP2,WNT11,WWP2,ZBED6,ZBTB42,ZBTB45,ZHX3,ZKSCAN3,ZNF18,ZNF540,ZNF658,ZP3 |
| GO_GLYCOSYLATION | 0.0e+00 | 0.0e+00 | 1125 | 267 | 30 | ALG1,ALG1L,B3GALT1,B3GAT3,B4GAT1,C1GALT1C1,C1GALT1C1L,CLN5,COG7,CRPPA,DPY19L1,DPY19L3,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GBA2,GXYLT2,LFNG,MAN1A1,MGAT5B,MUC2,POGLUT1,POGLUT3,SLC35C1,ST6GALNAC3,TMTC2,TMTC3,TRAK2 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1280 | 73 | ADIPOQ,APBB1,ATF7IP,ATP8B1,BACH2,BASP1,CBX5,CBX6,CBX7,CCDC85B,CITED1,CTNNBIP1,DPF1,DUSP22,ESR1,FAM220A,FOXN3,FOXO1,FOXP1,FZD1,GAS6,GLI2,GLI3,H1-0,H3C10,H3C12,H4C9,HIF1AN,HOXD8,HR,ID1,IRX2,JARID2,JAZF1,LGR4,MEN1,MYPOP,NR1H4,NUPR2,PCBP3,PEX2,PKIA,PPARA,PRICKLE1,PTCH1,PURB,RUNX1T1,SATB1,SKI,SKOR1,SNCA,SOX13,SOX18,SREBF1,STAT1,SUPT4H1,TCFL5,TFAP2A,TRIM6,TRIM66,TWIST1,USP2,WNT11,WWP2,ZBED6,ZBTB42,ZBTB45,ZHX3,ZKSCAN3,ZNF18,ZNF540,ZNF658,ZP3 |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 987 | 62 | ABCD2,ADORA1,ADRB2,ANKIB1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CARHSP1,CPTP,DISC1,ERCC4,F8A1,F8A3,FBXW8,FOXO1,FYCO1,GFAP,GGA3,GJA1,GPLD1,GPSM1,HERC1,HIF1A,IRS1,KDR,MAGEF1,MLYCD,MTCL1,MYEF2,NUP210,PDE3B,PFKFB2,PPARA,PRICKLE1,PRKACA,PRKCA,PTK2B,RAB26,RNFT1,ROCK2,RRAGA,SCARB1,SCOC,SESN3,SH3BP4,SLC25A12,SNCA,SNX1,SORL1,SREBF1,STK11,TENT5C,THRAP3,TMTC3,TNRC6C,TPCN1,TWIST1,VSIR,WDR91,WWP2,ZKSCAN3 |
| GO_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 1125 | 695 | 50 | ADAM10,ADIPOQ,AGR2,ANK3,CD9,CELSR2,CYTH3,DENND6A,DISC1,DUSP22,EFNB2,EPB41L4B,EPHA7,FN1,FRMD5,FSTL3,FZD4,GLI2,GLI3,IL18,ITGA3,ITGB1BP1,JAG2,JUP,KDR,KLRC4-KLRK1,LAMA1,LAMA5,LRFN3,MEN1,MINK1,PDE3B,PLXND1,PPARA,PRKCA,PRKX,PTK2B,RAG1,RGCC,ROCK2,SEMA5A,SERPINI1,SPINT2,SPOCK1,TENM3,TGFBR2,TNFSF14,VAV3,VSIR,ZP3 |
| GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 0.0e+00 | 0.0e+00 | 1125 | 327 | 33 | ADAM10,ADIPOQ,AGR2,ANK3,APPL1,ARL3,BBS2,DLG4,EFR3A,GAS6,GGA3,GOPC,GPHN,ITGA3,ITGB1BP1,JUP,LAMA5,LDLRAP1,LRRC7,MRAP2,PACS2,PKP2,PPP1R9B,PPP2R5A,PRKCH,PTCH1,RAB26,RAB3A,RAB3D,ROCK2,SLC9A3R1,SNAP47,STXBP1 |
| GO_REGULATION_OF_CELL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 491 | 41 | ADAM10,BCL9L,BVES,CDC42EP3,DISC1,DLG4,DNM3,EPHA7,FBXW8,FITM2,FN1,FZD4,ID1,ITGB1BP1,KDR,LIMK1,LPAR1,MAP3K13,MCF2,METRN,MYH10,NIN,PLXND1,PRAG1,PTK2B,RHOBTB1,ROBO2,RTN4R,SARM1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A3R1,STK11,TAOK2,TIAM1,TRAK2,YWHAH,ZSWIM5 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1125 | 1748 | 89 | ADAM10,ADIPOQ,ADORA1,AGR2,APBB1,ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,ARRB2,ASAH2,BCL11B,BDKRB2,CARD10,CASP9,CD200,CITED1,CRADD,CSRNP3,EFNB2,EPHA7,ESR1,EYA4,FBH1,FOXO1,FOXP1,FZD1,FZD3,GAS6,GDF11,GJA1,GLI2,GLI3,GPLD1,HIF1A,HIP1,HS1BP3,HSPB6,HYAL2,ID1,KDR,LIG4,LMNA,LPAR1,MAP3K5,MCF2,MEIS3,MIEN1,MT-CO2,NAA38,NLRP1,NLRP2,NR1H4,P2RX1,PPARA,PRKCA,PRKCH,PTK2B,RAG1,RASSF5,RGCC,RPS6KA2,SARM1,SEMA5A,SERPINB13,SGK1,SGMS1,SLC9A3R1,SMAD6,SNCA,SORL1,SORT1,STAT1,STXBP1,SULT1A4,TFAP2A,TIAM1,TM7SF3,TMEM14A,TNFAIP8L1,TNFSF14,TPD52L1,TWIST1,UCN,UNC13B,VAV3,WNT11,YWHAH,ZMAT3 |
| GO_HEAD_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 774 | 53 | ADCY1,ARRB2,ATP7A,BASP1,BBS2,BCL11B,BCR,CD9,CDON,CELSR2,CITED1,CLN5,COL4A1,COQ8B,CRISPLD1,DISC1,DIXDC1,EPHA7,ERBB4,FAT4,FZD1,FZD3,FZD4,GDPD5,GLI2,GLI3,GNG12,HERC1,HIF1A,ID1,IL11RA,IMMP2L,LPAR1,MAOB,MEN1,MYH10,NAGLU,NIN,PCDH18,PPP1R9B,PTCH1,ROBO2,RTN4R,SEMA5A,SEMA6D,SKI,SRR,SSBP3,SUN1,TGFBR2,TRAPPC9,YWHAH,ZNF365 |
| GO_MONOCARBOXYLIC_ACID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 128 | 21 | ABCD2,ABCD3,ADIPOQ,AIG1,ALDH3A2,ALDH5A1,AMACR,CRAT,CROT,CRYL1,ETFDH,IRS1,LIPE,MECR,MLYCD,MMAA,NUDT7,PEX2,PEX7,PPARA,TWIST1 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1870 | 93 | ADRB2,AGO1,AGRN,APBB1,ARRB1,ARRB2,ASH2L,ATF7IP,BCL11B,BCL9L,BEX1,BRF1,CDON,CITED1,CRTC1,CSRNP3,DBP,DPF1,ERBB4,ERCC2,ERLIN2,ESR1,EYA4,FOXO1,FSTL3,FZD1,FZD4,GLI2,GLI3,GRHL3,H1-0,HABP4,HELZ2,HIF1A,HLF,HOXD8,HYAL2,IL18,IRF4,ITGB1BP1,JUP,KLF14,LGR4,LMO2,LRP5,MAP3K5,MEIS3,MEN1,MRTFB,MT-CO2,MYRFL,NR1H4,NUDT16,PARM1,PBX1,PFKFB2,PLXND1,PPARA,PTCH1,PTK2B,RGCC,ROCK2,SCAP,SKI,SLC25A12,SLX4,SMAD6,SMARCD3,SMYD3,SOST,SOX13,SOX18,SPIDR,SPIRE2,SREBF1,SSBP3,STAT1,SUPT4H1,TFAP2A,THRAP3,TNRC6C,TOX2,TRIM44,TWIST1,UCN,WNT11,WWP2,YWHAH,ZBTB48,ZKSCAN3,ZMIZ2,ZNF287,ZP3 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1724 | 88 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ANKIB1,ANTXR1,ARRB1,ARRB2,ATG10,BRAT1,C6orf89,CARD10,CASP9,CCNYL1,CDC14B,CDON,CRADD,DISC1,DLG3,DLG4,DUSP22,EPHA7,ERBB4,FBH1,FBXW8,FN1,FOXO1,FZD1,FZD4,GAS6,GDF11,GGA3,GJA1,GPLD1,HABP4,HIP1,HSPA2,IL18,IRF4,ITGB1BP1,JARID2,JCAD,KDR,LMNA,LPAR1,MAGEF1,MAP3K13,MAP3K5,MAP4K2,MINK1,NLRP1,NLRP2,NPTN,NSMCE3,P2RX1,PECAM1,PPP2R5A,PRICKLE1,PRKACA,PRKCA,PTK2B,RASSF5,RGCC,RNFT1,ROCK2,SCAP,SH3RF3,SHC2,SMYD3,SNCA,SNX1,SORL1,SREBF1,STK11,TAOK2,TGFBR2,TIAM1,TMTC3,TNFRSF11A,TNK2,TPD52L1,TRIM6,UCN,UHMK1,VSIR,WNT11,WWP2 |
| GO_UROGENITAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 331 | 33 | ADIPOQ,ARL3,BASP1,CASP9,CITED1,COL4A1,CTNNBIP1,EFNB2,ENPEP,EPHA7,ESR1,FAT4,FSTL3,GDF11,GLI2,GLI3,HYAL2,IRX2,ITGA3,LAMA5,LGR4,PBX1,PECAM1,PRKX,PTCD2,PTCH1,ROBO2,SMAD6,STAT1,STK11,SULF1,TFAP2A,WNT11 |
| GO_RENAL_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 294 | 31 | ADIPOQ,ARL3,BASP1,CASP9,CITED1,COL4A1,CTNNBIP1,EFNB2,ENPEP,EPHA7,FAT4,FSTL3,GDF11,GLI2,GLI3,HYAL2,IRX2,ITGA3,LAMA5,LGR4,PBX1,PECAM1,PRKX,PTCD2,PTCH1,ROBO2,SMAD6,STAT1,SULF1,TFAP2A,WNT11 |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 879 | 57 | ADRB2,ANK3,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,ATPSCKMT,CHRNA9,CHRNE,CLDN16,CYB5A,DLG3,DLG4,FGF12,GAS6,GNB5,GPD1L,HSPA2,KCNJ1,LRRC7,MFSD3,MINK1,MRS2,MT-CO2,P2RX1,PLCB2,PLCD3,PRKACA,PTK2B,RNF207,SCN1B,SCNN1A,SCNN1G,SLC12A5,SLC25A23,SLC25A29,SLC30A4,SLC36A1,SLC46A1,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SPG7,STIM2,SURF1,TMEM175,TMEM37,TMEM63C,TPCN1,TWIST1,WWP2,YWHAH |
| GO_PROTEIN_O_LINKED_GLYCOSYLATION | 0.0e+00 | 0.0e+00 | 1125 | 116 | 20 | B3GALT1,B4GAT1,C1GALT1C1,C1GALT1C1L,CRPPA,GALNT1,GALNT11,GALNT18,GALNT2,GALNT7,GXYLT2,LFNG,MGAT5B,MUC2,POGLUT1,POGLUT3,SLC35C1,TMTC2,TMTC3,TRAK2 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1125 | 1559 | 82 | ABCD2,ADIPOQ,ADORA1,AGR2,APBB1,APPL1,ARRB2,ATP7A,BCR,BDKRB2,CASP9,CD200,CD9,DDAH1,DUSP22,EIF2AK1,ERCC4,ESR1,EYA4,FBH1,FOXO1,FOXP1,FZD1,FZD4,GJA1,HIF1A,HTRA1,HYAL2,IFNAR2,IL18,IRF4,KLRC4-KLRK1,LGR4,LMNA,LPL,MAGEF1,MAGI3,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,MUC2,NLRP1,NR1H4,NUDT16,NUP210,PPARA,PRKACA,PRKCA,PTK2B,RAB3A,RAB7B,RADX,RAG1,RNFT1,ROCK2,RTN4R,SARM1,SERPING1,SESN3,SH3RF3,SLC25A23,SNCA,SPIDR,SPIRE2,STAT1,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,TRIM44,TRIM6,TSPAN6,TWIST1,UCN,UNC13B,UNC93B1,ZKSCAN3,ZNF365,ZP3 |
| GO_CELL_CELL_JUNCTION_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1125 | 131 | 21 | CD9,CDH12,CDH17,CDH18,CDH7,CDH8,GJA1,GJC1,HEG1,JUP,MPP7,NR1H4,PARD6A,PECAM1,PKP2,PRKACA,PRKCA,PRKCH,ROCK2,VCL,WNT11 |
| GO_FATTY_ACID_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 104 | 19 | ABCD2,ABCD3,ADIPOQ,AIG1,ALDH3A2,AMACR,CRAT,CROT,ETFDH,IRS1,LIPE,MECR,MLYCD,MMAA,NUDT7,PEX2,PEX7,PPARA,TWIST1 |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 547 | 43 | ADH4,ALDH3A2,AMACR,APPL1,ASAH2,ATP7A,ATP8B1,BCO1,CHKA,CITED1,CLCN2,CYP2R1,CYP4V2,DGAT2,ELOVL6,ERLIN2,GBA2,GDE1,HIF1A,IDH2,INPP4A,ITPK1,LDLRAP1,LIPE,MAOB,MINPP1,MRS2,NR1H4,NUDT11,PFKFB2,PLCB2,PLCD3,PLPP6,PMVK,PTK2B,SCAP,SCARB1,SLC25A12,SNCA,SREBF1,SULT1A4,TG,TM7SF2 |
| GO_OSSIFICATION | 0.0e+00 | 0.0e+00 | 1125 | 396 | 36 | ADRB2,CITED1,CTNNBIP1,ENPP1,ERCC2,FAM20C,FAT4,FSTL3,FZD1,GLI2,GLI3,GPLD1,HIF1A,ID1,LGR4,LRP5,MEN1,MINPP1,PBX1,PEX7,PRKACA,PTCH1,PTK2B,RFLNB,SKI,SMAD6,SMOC1,SNX10,SORT1,SOST,SUN1,TFAP2A,TNFRSF11A,TWIST1,WNT11,ZHX3 |
| GO_REGULATION_OF_BODY_FLUID_LEVELS | 0.0e+00 | 0.0e+00 | 1125 | 506 | 41 | ADCY1,ADCY9,ADORA1,AGR2,ARRB1,ARRB2,ATP7A,ATP7B,C1GALT1C1,CAPZA2,CBX5,CD9,CELSR2,CHRM3,CSRP1,ERBB4,F2RL2,F8,GAS6,GGCX,GJA1,GRHL3,H3C10,H3C12,HEG1,HIF1A,HMG20B,HYAL2,ITPK1,MT-CO2,P2RX1,PRKACA,PRKCA,PRKCH,SCNN1A,SCNN1G,SERPING1,STXBP1,UCN,VAV3,VCL |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1301 | 72 | ABHD13,ABHD17A,ACADSB,AGRN,ALDH4A1,ALDH5A1,ALDH7A1,ANKIB1,AP2A2,ARRB1,ARRB2,ASAH2,BCKDHB,C17orf97,CEMIP2,CLN5,CSAD,DDAH1,DISC1,ENC1,ENPEP,ERLIN2,F8A1,F8A3,FBXL16,FBXL4,FBXO21,FBXO33,FBXW8,FOXO1,GBA2,GFAP,GGA3,GJA1,GM2A,GPLD1,HECTD3,HYAL2,MAGEF1,MAOB,MLYCD,NAGLU,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,PCYOX1L,PRICKLE1,PRKACA,PTK2B,RAB26,RMND5B,RNF123,RNFT1,SCARB1,SDC3,SLC44A1,SNCA,SNX1,SORL1,SULT1A4,TMTC3,TRIM58,TST,TYMP,UBE2D4,UBE2L6,USP2,USP48,WDR91,WWP2 |
| GO_ANION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 634 | 46 | ABCD3,ADORA1,ATP8B1,ATP8B3,BDKRB2,CLCN2,CPTP,CROT,ENPP1,GJA1,GLRB,GOPC,LRRC8B,MPC1,NR1H4,PCTP,PITPNC1,PLA2G12A,PLA2G2C,PPARA,PPFIA3,PRAF2,RAB3A,SCARB1,SLC12A5,SLC16A12,SLC25A12,SLC25A18,SLC25A23,SLC25A29,SLC25A42,SLC35A1,SLC36A1,SLC46A1,SLC4A4,SLC51A,SLC9A3R1,SLC9A6,SLC9A7,SNCA,STXBP1,TCAF1,TG,TNFRSF11A,TTYH3,UNC13B |
| GO_PHOSPHOLIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 432 | 37 | ACP6,ALDH5A1,BPNT1,CDS1,CHKA,EFR3A,ETNK2,FITM2,GDE1,GPD1L,GPLD1,INPP4A,IRS1,LPCAT3,LPCAT4,LPL,NR1H4,PCTP,PIGM,PIGN,PIGX,PLA2G12A,PLA2G2C,PLAAT3,PLCB2,PLPPR2,PMVK,PTK2B,PTPN13,RAB4A,SCARB1,SGMS1,SLC44A1,SNCA,VAV3,WDR91,ZP3 |
| GO_GROWTH | 0.0e+00 | 0.0e+00 | 1125 | 990 | 60 | ADAM10,ADRB1,ADRB2,AGR2,AGRN,APBB1,BASP1,BBS2,BRAT1,CCDC85B,CCM2,CD9,CTC1,DCBLD2,DISC1,ENPP1,EPHA7,ERBB4,ERCC2,ESR1,ETNK2,FN1,GAS6,GJA1,GLI2,GLI3,HEG1,HIF1A,HYAL2,IGFBP7,JARID2,LIMK1,MAP3K13,NIN,NSMCE3,PPARA,PPP1R9B,PTCH1,PTK2B,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SH3BP4,SLC12A5,SLC9A6,SPOCK1,STK11,TAOK2,TGFBR2,TIAM1,TMEM8B,UCN,VCL,WNT11,ZMAT3,ZP3 |
| GO_SYNAPSE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 414 | 36 | ABHD17A,ACTBL2,ADAM10,AGRN,ANK3,C1QL1,CDH8,COL4A1,DISC1,DLG3,DLG4,DNM3,EFNB2,EPHA7,ERBB4,FZD1,GLRB,GPHN,ITGA3,LRFN3,MYH10,NPTN,PCDH17,PCDHB2,PICK1,PLXND1,RAB3A,ROBO2,SEMA3F,SLC9A6,SNCA,TANC1,THBS2,TIAM1,UNC13B,ZNF365 |
| GO_PEPTIDE_SECRETION | 0.0e+00 | 0.0e+00 | 1125 | 641 | 46 | ADORA1,APBB1,ARRB1,C1QTNF4,CAVIN1,CD200,COPG2,CPTP,EXOC3L1,FN1,FOXP1,GAS6,GJA1,GPLD1,HIF1A,HYAL2,IDH2,IRS1,LGR4,LPL,LRP5,MYH10,NLRP1,NLRP2,NR1H4,PARD6A,PFKFB2,PRKCA,RAB11FIP1,RAB3A,RAB3D,RAPGEF4,RGCC,SERGEF,SIRT3,SNX19,SORL1,SREBF1,STXBP4,TIAM1,TM7SF3,TRIM6,TWIST1,UCN,UNC13B,VGF |
| GO_LIPID_OXIDATION | 0.0e+00 | 0.0e+00 | 1125 | 101 | 18 | ABCD2,ABCD3,ADH4,ADIPOQ,ALDH3A2,AMACR,CRAT,CROT,CYP4V2,DGAT2,ETFDH,IRS1,MECR,MLYCD,PEX2,PEX7,PPARA,TWIST1 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 976 | 59 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,ATPSCKMT,CAMK2N2,CARD10,CCNJL,CCNYL1,CD200,CDC14B,DLG3,DLG4,DUSP22,FZD4,GAS6,HEG1,HYAL2,IL18,INKA2,IRS1,ITGB1BP1,LIMK1,LPAR1,LRP5,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,MVP,PARM1,PFKFB2,PKIA,PPM1E,PPP2R5A,PRKACA,PTK2B,RGCC,SHC2,SLC9A3R1,SMYD3,SNCA,SORL1,SPRY3,STK11,STK38,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,UCN,VAV3,WDR91,WNT11,ZFYVE28 |
| GO_MEMBRANE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 875 | 55 | ABCD2,ADCK1,ADRB2,AGRN,ANK3,AP2A2,ARRB1,ARRB2,ATP5F1D,ATP8B1,ATP8B3,CD9,CHMP7,CPTP,DLG4,DNAJC6,DNM3,F8,FAT4,FZD4,GAS6,GBA2,GLRB,GPHN,HIP1,HYAL2,IGHV4-34,LDLRAP1,LMNA,MYH10,NEK9,PICK1,PRKCA,RAB3A,RAB7B,REEP2,RTL10,SLC25A46,SNAP47,SNCA,SPG7,SPIRE2,STX17,STXBP1,SUN1,TMEM14A,TMEM175,TRAM2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9,VAV3,VPS18,YWHAH |
| GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1125 | 750 | 50 | ADIPOQ,CCDC85B,CITED1,DIXDC1,DNM3,EFNB2,ENPP1,EPHA7,ERBB4,FOXO1,FSTL3,GDF11,GLI2,GLI3,H4C9,ID1,IDH2,IL18,ITGB1BP1,LILRB3,LPAR1,LRP5,MCF2,MEN1,PBX1,PKP2,PPARA,PRAG1,PRICKLE1,PTCH1,PTK2B,RFLNB,RTN4R,RUNX1T1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SKI,SMAD6,SORL1,SORT1,SPOCK1,STAT1,TRAK2,TRIM6,TWIST1,YWHAH,ZNF365 |
| GO_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1125 | 831 | 53 | ADORA1,ANK3,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,BDKRB2,CHRNA9,CLDN16,CLN5,DGAT2,DISC1,DLG4,DMXL2,EIF2AK1,ENPP1,ESR1,F2RL2,FGF12,GJA1,GPD1L,GPR157,HIF1A,HYAL2,KDR,LPAR1,NPTN,NR1H4,P2RX1,PLCB2,PLCD3,PRKACA,PTK2B,SCN1B,SCNN1A,SCNN1G,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SNX10,STIM2,TMEM175,TMTC2,TPCN1 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 1125 | 1208 | 67 | ADCY1,ADCY9,ADH4,ADIPOQ,ADRB2,AGRN,APPL1,ARRB1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,BCR,CASP9,CCS,CHRM3,COL4A1,DGAT2,ENPP1,ESR1,FOXO1,FZD4,GAS6,GJA1,GNB5,GNRHR2,GPLD1,HIF1A,HTR1D,ID1,IL18,IRS1,JUP,KLF9,KLRC4-KLRK1,LPAR1,LPL,LRP5,MAP3K5,MEN1,NR1H4,PDE3B,PPP1R9B,PRKACA,PRKCA,PTCH1,PTK2B,ROCK2,RRAGA,SCARB1,SESN3,SGMS1,SH3BP4,SLC9A3R1,SMYD3,SNCA,SORL1,SPIDR,SREBF1,STAT1,STXBP4,SULT1A4,TIAM1,UNC13B,WNT11 |
| GO_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 0.0e+00 | 0.0e+00 | 1125 | 268 | 28 | ADIPOQ,AGR2,ANK3,APPL1,BBS2,EFR3A,GAS6,GGA3,GOPC,ITGA3,ITGB1BP1,JUP,LAMA5,LDLRAP1,LRRC7,MRAP2,PACS2,PKP2,PPP1R9B,PPP2R5A,PRKCH,PTCH1,RAB26,RAB3A,RAB3D,ROCK2,SLC9A3R1,STXBP1 |
| GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 1125 | 763 | 50 | ADIPOQ,ADORA1,BCHE,BCL11B,CD200,CD9,CTNNBIP1,DDAH1,DIS3L2,DLG3,EFNB2,EIF2AK1,ERBB4,FGFRL1,GDF11,GJA1,GLI3,GPLD1,H2AC6,IDH2,IGFBP7,ITGB1BP1,JARID2,KLF9,LMNA,MEN1,NUDT6,NUPR2,PEX2,PTCH1,PTK2B,PTPN14,PTPRM,RASSF5,RGCC,RPS6KA2,SH3BP4,SKI,SLC9A3R1,SMAD6,SPINT2,STAT1,STK11,SULF1,SYNJ2BP,TFAP2A,TGFBR2,TP53I11,VSIR,WNT11 |
| GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 414 | 35 | ABCD2,ADIPOQ,ADORA1,BCL11B,CLCN2,DGAT2,ELOVL6,ERLIN2,FITM2,GOLM1,GPLD1,HELZ2,IGFBP7,IRS1,LDLRAP1,MLYCD,NR1H4,PDE3B,PMVK,PPARA,PPP2R5A,PTK2B,RGL1,SCAP,SCARB1,SIRT3,SMARCD3,SNCA,SORL1,SREBF1,TM7SF2,TWIST1,VAV3,WDR91,ZP3 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 620 | 44 | ADIPOQ,ARPP19,ARRB1,ARRB2,BDKRB2,CAMK2N2,CHRNA9,DUSP22,ELFN2,ENPP1,FOXO1,GPD1L,HEG1,HINT2,HMG20B,HYAL2,INKA2,ITGB1BP1,JARID2,LIMK1,LRP5,MEN1,MVP,PARD6A,PHACTR2,PKIA,PPM1E,PPP1R9B,PTPN13,ROCK2,SIRT3,SKI,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,STK38,SYNJ2BP,TRIM44,TWIST1,UCN,ZFYVE28 |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 872 | 54 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,CAMK2N2,CARD10,CCNJL,CCNYL1,DLG3,DLG4,DUSP22,FZD4,GAS6,HEG1,HYAL2,IL18,INKA2,IRS1,ITGB1BP1,LPAR1,LRP5,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,MVP,PFKFB2,PKIA,PPM1E,PPP2R5A,PRKACA,PTK2B,RGCC,SHC2,SLC9A3R1,SMYD3,SNCA,SORL1,SPRY3,STK11,STK38,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,UCN,VAV3,WDR91,WNT11,ZFYVE28 |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 723 | 48 | ABCD2,ABCD3,ACSM2B,ADIPOQ,AMACR,ARPP19,ASAH2,BCO1,CHST12,CLCN2,COQ8B,CSAD,CYP2R1,DGAT2,DHFR2,ELOVL6,ENPP1,ERLIN2,FADS3,FOXO1,HSD17B8,LPL,MECR,MLYCD,MMAA,MRI1,MTHFR,NR1H4,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,PLCB2,PLCD3,PLPP6,PMVK,PPARA,PTGS1,PTK2B,SCAP,SLC25A12,SNCA,SREBF1,SRR,TM7SF2,TYMP,UROS |
| GO_REGULATION_OF_PEPTIDE_SECRETION | 0.0e+00 | 0.0e+00 | 1125 | 511 | 39 | ADORA1,APBB1,ARRB1,C1QTNF4,CD200,CPTP,FN1,FOXP1,GAS6,GJA1,GPLD1,HIF1A,HYAL2,IDH2,IRS1,LGR4,LPL,LRP5,MYH10,NLRP1,NLRP2,NR1H4,PARD6A,PFKFB2,PRKCA,RAB11FIP1,RAPGEF4,RGCC,SERGEF,SIRT3,SORL1,SREBF1,STXBP4,TIAM1,TM7SF3,TRIM6,TWIST1,UCN,UNC13B |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 831 | 52 | ABCD2,ADRB2,ANKIB1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CARHSP1,CPTP,DISC1,ERCC4,F8A1,F8A3,FBXW8,FOXO1,FYCO1,GFAP,GPLD1,GPSM1,HERC1,HIF1A,IRS1,KDR,MAGEF1,MLYCD,MTCL1,MYEF2,PFKFB2,PPARA,PRICKLE1,PRKACA,PRKCA,PTK2B,RNFT1,ROCK2,RRAGA,SCARB1,SCOC,SESN3,SH3BP4,SNCA,SORL1,SREBF1,STK11,TENT5C,THRAP3,TMTC3,TNRC6C,TPCN1,TWIST1,WDR91,ZKSCAN3 |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 990 | 58 | ACP6,ADIPOQ,AGO1,ASH2L,ATP7A,BCL11B,BCR,BVES,CASP9,CDH17,CTC1,CTNNBIP1,DHTKD1,EIF2AK1,ERCC2,FAM20C,FOXP1,FSTL3,GAS6,GLI2,GLI3,H3C10,H3C12,H4C9,HIF1A,HYAL2,IL18,IRF4,ITM2A,JAG2,JARID2,KDR,LFNG,LIG4,LILRB3,LMO2,LRP5,NBEAL2,PBX1,PRKCA,PRKX,PTK2B,PURB,RAB7B,RAG1,RBM47,SATB1,SNX10,SOX13,SSBP3,STAT1,STK11,TGFBR2,TNFRSF11A,TNRC6C,TRIM58,VSIR,WDR78 |
| GO_REGULATION_OF_GROWTH | 0.0e+00 | 0.0e+00 | 1125 | 680 | 46 | ADAM10,ADRB1,ADRB2,AGR2,AGRN,APBB1,BASP1,BBS2,BRAT1,CCDC85B,DCBLD2,DISC1,ENPP1,EPHA7,ERBB4,FN1,GAS6,GJA1,HIF1A,HYAL2,IGFBP7,JARID2,LIMK1,MAP3K13,NSMCE3,PPARA,PPP1R9B,PTCH1,PTK2B,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SH3BP4,SPOCK1,STK11,TAOK2,TGFBR2,TMEM8B,UCN,WNT11,ZMAT3,ZP3 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1125 | 537 | 40 | ABHD17A,ADAM10,ADIPOQ,AGR2,ANK3,APPL1,B3GAT3,CARD10,CROCC,EFNB2,ERBB4,GAS6,GLI3,GOPC,GPD1L,HYAL2,ITGA3,ITGB1BP1,JUP,LDLRAP1,LMNA,MRAP2,MTCL1,NPTN,PARD6A,PKIA,PPP1R9B,PPP2R5A,PRKACA,PRKCH,PTPN14,RASSF5,ROCK2,SORL1,SPIDR,SREBF1,STK11,TCAF1,UHMK1,YWHAH |
| GO_RESPONSE_TO_HORMONE | 0.0e+00 | 0.0e+00 | 1125 | 994 | 58 | ABCA3,ADCY1,ADCY9,ADIPOQ,AGRN,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,BBS2,BCHE,CASP9,CHRM3,CITED1,ENPP1,ESR1,FOXO1,FOXP1,GAS2L1,GJA1,GNRHR2,GPLD1,IGFBP7,IRS1,ITGA3,KLF9,LGR4,LMO2,LPL,MAOB,MEN1,NR1H4,PAPPA,PAQR8,PDE3B,PPARA,PPP1R9B,PRKACA,PTCH1,PTK2B,ROBO2,ROCK2,SCAP,SESN3,SMYD3,SORL1,SORT1,SOST,SREBF1,STAT1,STXBP1,STXBP4,TGFBR2,UCN,VGF,YWHAH |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 587 | 42 | ADIPOQ,ARPP19,ARRB1,ARRB2,BDKRB2,CAMK2N2,CHRNA9,CSRNP3,DLG3,DUSP22,ELFN2,ENPP1,FOXO1,GPD1L,HEG1,HYAL2,INKA2,ITGB1BP1,LRP5,MARF1,MEN1,MVP,PARD6A,PHACTR2,PKIA,PPARA,PPM1E,PPP1R9B,PPP2R5A,PTPN13,ROCK2,SIRT3,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,STK38,SYNJ2BP,TWIST1,ZFYVE28 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1189 | 65 | ADIPOQ,AGO1,APBB1,ARPP19,ARRB1,ARRB2,BDKRB2,CAMK2N2,CHRNA9,COL28A1,DUSP22,EIF2AK1,ELFN2,ENC1,ENPP1,F8A1,F8A3,FOXO1,GAS6,GGA3,GPD1L,HEG1,HINT2,HMG20B,HYAL2,INKA2,ITGB1BP1,ITM2A,JARID2,LIMK1,LRP5,MEN1,MVP,PAIP2B,PARD6A,PHACTR2,PKIA,PPM1E,PPP1R9B,PTPN13,RAG1,RECK,ROCK2,SERPINB13,SERPING1,SERPINI1,SIRT3,SKI,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPINT2,SPOCK1,SPRY3,STK38,SYNJ2BP,TNFSF14,TNRC6C,TRIM44,TWIST1,UCN,ZFYVE28,ZNF540 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1125 | 1135 | 63 | ADCY1,ADCY9,ADIPOQ,ADRB2,AGRN,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,BCHE,CD9,CHRM3,CITED1,COL4A1,ENPP1,ERLIN2,FOXO1,GJA1,GLRB,GNB5,GNRHR2,GPLD1,HLCS,HTR1D,ID1,IRS1,JUP,LPL,MAP3K5,MEN1,MTHFR,NLRP1,NR1H4,NSMCE3,P2RX1,PDE3B,PPARA,PPP1R9B,PRKACA,PTK2B,RNFT1,ROCK2,RRAGA,SCAP,SESN3,SH3BP4,SLC9A3R1,SNCA,SORL1,SORT1,SPIDR,SREBF1,SRR,STAT1,STXBP4,SULT1A4,TIAM1,TRDMT1,UROS,VGF |
| GO_CELL_CELL_SIGNALING_BY_WNT | 0.0e+00 | 0.0e+00 | 1125 | 521 | 39 | AGO1,AP2A2,ARHGEF19,ARRB2,BCL9L,CELSR2,CITED1,CMAHP,CTNNBIP1,CXXC4,DISC1,DIXDC1,ESR1,FOXO1,FZD1,FZD3,FZD4,GLI3,GRHL3,ITGA3,JUP,LGR4,LRP5,LYPD6,PARD6A,PLCB2,PRICKLE1,PRICKLE2,RECK,SEMA5A,SKI,SLC9A3R1,SOST,STK11,SULF1,TIAM1,TNRC6C,VANGL1,WNT11 |
| GO_EMBRYONIC_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 592 | 42 | ADIPOQ,BCR,CDON,CHRNA9,COL4A2,FN1,FZD1,FZD3,GJA1,GJB5,GLI2,GLI3,GRHL3,HIF1A,IRX2,ITGA3,JAG2,LAMA5,LHFPL5,LMBR1,LRP5,LUZP1,MTHFR,NAGLU,PBX1,PDZD7,POGLUT1,PRICKLE1,PRKACA,PTCH1,RECK,RNF207,ROCK2,SKI,SLC9A3R1,SOX18,SPINT2,SULF1,TFAP2A,TGFBR2,TWIST1,WNT11 |
| GO_NOTCH_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1125 | 193 | 23 | ADAM10,ARRB1,FAT4,GALNT11,GDPD5,HIF1AN,ITGB1BP1,JAG2,LFNG,LLGL1,LLGL2,NR1H4,PBX1,PLXND1,POGLUT1,PRAG1,ROBO2,SLC35C1,STAT1,SUSD5,SYNJ2BP,TGFBR2,WWP2 |
| GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 431 | 35 | ABCD2,ADORA1,ADRB2,ANKIB1,DISC1,FBXW8,FOXO1,FYCO1,GGA3,GJA1,GPLD1,GPSM1,HIF1A,IRS1,KDR,MAGEF1,PFKFB2,PPARA,PRICKLE1,PTK2B,RNFT1,ROCK2,SCOC,SESN3,SH3BP4,SNCA,SNX1,SORL1,STK11,TMTC3,TNRC6C,TPCN1,TWIST1,VSIR,WWP2 |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 547 | 40 | AGRN,APBB1,CDON,CRTC1,DISC1,DLG4,ENC1,FBXW8,FN1,FZD1,FZD3,FZD4,GDPD5,GLI2,GLI3,HIF1A,HMG20B,ITGA3,LIG4,LIMK1,LPAR1,LRRC7,MAP3K13,METRN,NIN,NPTN,PLXND1,PRKCH,PTK2B,ROBO2,SCN1B,SEMA5A,SERPINI1,SLC25A12,SMARCD3,STK11,TENM3,THBS2,TIAM1,ZNF365 |
| GO_DEPHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 1125 | 479 | 37 | ACP2,ACP6,ACPP,ADORA1,ARPP19,B3GAT3,BPNT1,CDC14B,CSRNP3,DLG3,DNAJC6,DUSP22,ELFN2,EYA4,FAM220A,GPLD1,INPP4A,LHPP,MARF1,MINPP1,NT5M,NUDT16,PFKFB2,PHACTR2,PLPP6,PLPPR2,PPEF1,PPM1E,PPM1H,PPP1R9B,PPP2R5A,PTPN13,PTPN14,PTPRM,ROCK2,SSH2,STK11 |
| GO_WOUND_HEALING | 0.0e+00 | 0.0e+00 | 1125 | 572 | 41 | ARHGEF19,ARRB1,ARRB2,C1GALT1C1,C6orf89,CAPZA2,CBX5,CD9,CSRP1,DCBLD2,EPB41L4B,ERBB4,F2RL2,F8,FN1,GAS6,GGCX,GJA1,GLI3,GRHL3,H3C10,H3C12,HIF1A,HMG20B,ITPK1,MAP3K5,MCAM,MYH10,P2RX1,PECAM1,PPARA,PRKACA,PRKCA,PRKCH,RAB3A,SCARB1,SERPING1,STXBP1,TGFBR2,VAV3,VCL |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 0.0e+00 | 0.0e+00 | 1125 | 503 | 38 | ADORA1,ADRB1,ADRB2,ARHGAP28,ATP7A,BBS2,BDKRB2,CAPZA2,CDC42EP3,CHRM3,DISC1,EPHA7,EVL,FN1,GBA2,GJA1,HTR1D,IQGAP2,ITGB1BP1,LIMK1,MAP3K13,P2RX1,PICK1,PTK2B,PTPRM,ROCK2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC12A5,SLC9A3R1,SPIRE2,TMOD2,UCN,VAV3 |
| GO_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 1125 | 250 | 26 | AP2A2,ARHGEF19,ARRB2,BASP1,CELSR2,CITED1,ESR1,FZD1,FZD3,FZD4,GRHL3,LGR4,ODAPH,PARD6A,PRICKLE1,PRICKLE2,RNF207,ROBO2,STAT1,SULF1,TFAP2A,TGFBR2,TIAM1,TWIST1,VANGL1,WNT11 |
| GO_CIRCULATORY_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 554 | 40 | ADIPOQ,ADORA1,ADRB1,ADRB2,BBS2,BCR,BDKRB2,BVES,CHRM3,CTNNBIP1,CXADR,DDAH1,ENPEP,FGF12,FGFBP3,GAS6,GJA1,GJC1,GPD1L,HEG1,HTR1D,IMMP2L,ITGB1BP1,JUP,LRP5,P2RX1,PKP2,PPARA,PRKACA,PTGS1,PTPRM,RNF207,ROCK2,SCN1B,SERPING1,SGK1,SREBF1,STAT1,TBC1D8,UCN |
| GO_NEGATIVE_REGULATION_OF_LOCOMOTION | 0.0e+00 | 0.0e+00 | 1125 | 396 | 33 | ADIPOQ,ADORA1,BCR,CARD10,CCDC125,CD200,DUSP22,ERBB4,EVL,FRMD5,GJA1,HYAL2,IDH2,ITGB1BP1,JUP,KLRC4-KLRK1,PTPRM,RECK,RGCC,ROBO2,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A3R1,SPINT2,SRGAP1,SULF1,SYNJ2BP,TCAF1,VCL,WNT11 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1710 | 82 | ADRB2,AGO1,AGRN,APBB1,ARRB1,ASH2L,ATF7IP,BCL11B,BCL9L,BEX1,BRF1,CDON,CITED1,CRTC1,CSRNP3,DBP,DPF1,ERBB4,ERCC2,ERLIN2,ESR1,FOXO1,FSTL3,FZD1,FZD4,GLI2,GLI3,GRHL3,H1-0,HABP4,HELZ2,HIF1A,HLF,HOXD8,HYAL2,IL18,IRF4,ITGB1BP1,JUP,KLF14,LGR4,LMO2,LRP5,MAP3K5,MEIS3,MEN1,MRTFB,MYRFL,NR1H4,PBX1,PLXND1,PPARA,PTCH1,RGCC,ROCK2,SCAP,SKI,SMAD6,SMARCD3,SMYD3,SOST,SOX13,SOX18,SREBF1,SSBP3,STAT1,SUPT4H1,TFAP2A,THRAP3,TNRC6C,TOX2,TRIM44,TWIST1,UCN,WNT11,WWP2,YWHAH,ZBTB48,ZKSCAN3,ZMIZ2,ZNF287,ZP3 |
| GO_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | 0.0e+00 | 0.0e+00 | 1125 | 181 | 22 | AP2A2,ARHGEF19,ARRB2,CELSR2,CITED1,ESR1,FOXP1,FZD1,FZD3,FZD4,GJA1,GRHL3,LGR4,PARD6A,PRICKLE1,PRICKLE2,RNF207,STAT1,SULF1,TIAM1,VANGL1,WNT11 |
| GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 0.0e+00 | 1125 | 274 | 27 | ADIPOQ,CDH12,CDH17,CDH18,CDH7,CDH8,CELSR2,CLDN11,CLDN16,CLDN9,CXADR,FAT1,FAT4,FGFRL1,LRFN3,NPTN,PCDH17,PCDH18,PCDH7,PCDHA3,PCDHB2,PCDHGB4,PECAM1,PTPRM,ROBO2,TENM3,TGFBR2 |
| GO_RESPONSE_TO_GROWTH_FACTOR | 0.0e+00 | 0.0e+00 | 1125 | 732 | 47 | APPL1,ARRB2,ATP7A,BCL9L,CITED1,COL4A2,DUSP22,ERBB4,FAM20C,FAT4,FGF12,FGF5,FGFBP3,FGFRL1,FSTL3,FZD1,FZD4,GAS6,HIF1A,HTRA1,HYAL2,ID1,ITGA3,ITGB1BP1,JCAD,KDR,MEN1,NPTN,NREP,PARD6A,PEG10,PPP1R9B,ROCK2,SKI,SKOR1,SLC9A6,SMAD6,SNCA,SORL1,SORT1,SOST,SPINT2,SPRY3,STK11,SULF1,TGFBR2,TWIST1 |
| GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1125 | 337 | 30 | ARHGAP24,ARHGAP28,ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,BCR,CCDC125,CDON,CYTH3,DEPDC7,F2RL2,HEG1,IQSEC1,ITGA3,LPAR1,MAPRE2,MCF2,PRAG1,PSD3,RALGAPA2,RASA4,RHOBTB1,RTN4R,SIPA1L2,SPRY3,SRGAP1,STMN3,TIAM1,VAV3 |
| GO_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 1125 | 402 | 33 | ACAP3,ADRB1,AGRN,ARHGAP24,ARHGAP28,ARHGEF19,ARRB1,ASAP3,BCR,CCDC125,CHML,ELMOD1,EVI5L,GNB5,GRHL3,IQSEC1,LLGL1,LLGL2,MAPRE2,PTK2B,RALGAPA2,RASA4,RINL,RTN4R,SIPA1L2,SRGAP1,TBC1D16,TBC1D2,TBC1D24,TBC1D8,TIAM1,VAV3,WNT11 |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 0.0e+00 | 1125 | 687 | 45 | ARHGEF19,ARRB1,ARRB2,ATP7A,C1GALT1C1,C6orf89,CAPZA2,CBX5,CD9,CSRP1,DCBLD2,EPB41L4B,ERBB4,F2RL2,F8,FN1,GAS6,GGCX,GJA1,GLI3,GRHL3,H3C10,H3C12,HIF1A,HMG20B,ITPK1,MAP3K5,MCAM,MYH10,NREP,P2RX1,PECAM1,PPARA,PRKACA,PRKCA,PRKCH,RAB3A,RTN4R,SARM1,SCARB1,SERPING1,STXBP1,TGFBR2,VAV3,VCL |
| GO_COFACTOR_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 449 | 35 | ACSM2B,ADH4,ALDH5A1,BTD,COQ8B,CROT,CYB5A,DGAT2,DHFR2,EIF2AK1,ELOVL6,FAR2,GPHN,GSTA4,GSTK1,HLCS,HSD17B8,IDH2,MAOB,MAT2A,MAT2B,MLYCD,MMAA,MOCS1,MOCS3,MPC1,MRI1,MT-CO2,MTHFR,NUDT7,PMVK,SLC25A39,SLC46A1,SNCA,UROS |
| GO_LIPID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1125 | 241 | 25 | ABCD2,ABCD3,ADH4,ADIPOQ,ALDH3A2,AMACR,B3GALT1,BPNT1,CRAT,CROT,CYP4V2,DGAT2,EFR3A,ETFDH,GBA2,IRS1,MECR,MLYCD,PEX2,PEX7,PLPP6,PLPPR2,PPARA,SLC35C1,TWIST1 |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 1146 | 62 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,ARRB2,BRAT1,CARD10,CCNYL1,CDON,DLG3,DLG4,DUSP22,EPHA7,ERBB4,FBH1,FZD1,FZD4,GAS6,GDF11,GPLD1,HIF1A,HSPA2,IL18,IRS1,ITGB1BP1,JCAD,KDR,LPAR1,MAP3K13,MAP3K5,MAP4K2,MINK1,MT-CO2,NPTN,NR1H4,PECAM1,PFKFB2,PPP2R5A,PRKACA,PRKCA,PTK2B,RGCC,ROCK2,SH3RF3,SHC2,SLC25A12,SMYD3,SNCA,STK11,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TNK2,TPD52L1,TRIM6,UCN,VAV3,WNT11,ZP3 |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1125 | 622 | 42 | BBS2,BRAT1,BVES,CHMP7,COPG2,CROCC,DNM3,F8,F8A1,F8A3,FYCO1,GJA1,HIF1A,KIF3A,LLGL1,LLGL2,MAP4K2,MYH10,NIN,PCDH17,PEX1,PPFIA3,PRKACA,RAB3A,RAB3D,SEPTIN5,SLC9A3R1,SNCA,SPIRE2,STK11,STX17,STXBP1,SUN1,SYNJ2BP,TRAK2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9,TRIM58,UNC13B,VPS18 |
| GO_KIDNEY_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 140 | 19 | ADIPOQ,BASP1,CITED1,CTNNBIP1,EFNB2,EPHA7,FAT4,GDF11,GLI3,IRX2,LAMA5,LGR4,PBX1,PECAM1,PTCH1,ROBO2,SMAD6,STAT1,WNT11 |
| GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 390 | 32 | AGRN,APBB1,ATP7A,CDC42EP3,CROCC,CRTC1,DISC1,DLG4,DNM3,ENC1,FBXW8,FN1,FZD1,FZD4,ITGA3,LIMK1,LPAR1,LRRC7,MAP3K13,METRN,MIEN1,NIN,NPTN,PLXND1,PTK2B,ROBO2,SCN1B,SEMA5A,SERPINI1,STK11,TENM3,TIAM1 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 0.0e+00 | 0.0e+00 | 1125 | 649 | 43 | ADAM10,ADCY9,ATP7A,CCM2,CITED1,ERCC2,ETNK2,FBXW8,FZD1,FZD3,GJB5,GLI2,GLI3,GRHL3,HEG1,HIF1A,ITPK1,JAG2,LFNG,LIG4,LUZP1,MTHFR,MYH10,PBX1,PLCD3,POGLUT1,PRICKLE1,PRKACA,PTCH1,SKI,SOX18,SPINT2,SSBP3,STMN3,SULF1,TANC2,TENT5C,TFAP2A,TGFBR2,TWIST1,WNT11,ZFP14,ZP3 |
| GO_NEGATIVE_REGULATION_OF_GROWTH | 0.0e+00 | 0.0e+00 | 1125 | 247 | 25 | ADRB1,ADRB2,APBB1,BBS2,CCDC85B,DCBLD2,ENPP1,EPHA7,GJA1,HIF1A,HYAL2,JARID2,PPARA,PPP1R9B,PTCH1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SH3BP4,STK11,TGFBR2,WNT11 |
| GO_FATTY_ACID_BETA_OXIDATION | 0.0e+00 | 0.0e+00 | 1125 | 71 | 14 | ABCD2,ABCD3,ADIPOQ,AMACR,CRAT,CROT,ETFDH,IRS1,MECR,MLYCD,PEX2,PEX7,PPARA,TWIST1 |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 860 | 51 | ANK3,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,ATPSCKMT,CHRNA9,CLCN2,CLDN16,CYB5A,FGF12,GAS6,GLRB,GNB5,GPD1L,HSPA2,KCNJ1,MFSD3,MRS2,MT-CO2,PLCB2,PLCD3,PRKACA,PTK2B,RNF207,SCN1B,SCNN1A,SCNN1G,SLC12A5,SLC25A23,SLC30A4,SLC36A1,SLC46A1,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SPG7,STIM2,SURF1,TMEM175,TMEM37,TPCN1,TTYH3,TWIST1,WWP2,YWHAH |
| GO_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1125 | 1223 | 64 | ACTR5,APBB1,ARRB1,ASH2L,ATF7IP,BRD3,C6orf89,CBX6,CBX7,CHMP7,CTC1,DIS3L2,DPF1,ERCC2,ERCC4,ESR1,EYA4,FBH1,H1-0,H2AC11,H2AC6,H2AJ,H2AW,H2BC4,H3C10,H3C12,H4C9,HLCS,HMG20B,HR,HSPA2,IK,IRF4,JARID2,LIG4,LMNA,MAP10,MEN1,MTHFR,NAP1L3,NAP1L5,NR1H4,NSL1,PRKCA,RAG1,RNF212,SATB1,SIRT3,SKI,SLX4,SMARCD3,SMYD3,SNCA,SREBF1,SUN1,SUPT4H1,TSPYL1,TUBG2,TWIST1,UCN,YLPM1,ZBTB48,ZMIZ2,ZNF365 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 1125 | 709 | 45 | ADCY1,ADCY9,ADIPOQ,ADRB2,AGRN,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,CHRM3,COL4A1,ENPP1,FOXO1,GJA1,GNB5,GNRHR2,GPLD1,HTR1D,ID1,IRS1,JUP,LPL,MAP3K5,MEN1,NR1H4,NSMCE3,PDE3B,PPP1R9B,PRKACA,ROCK2,RRAGA,SESN3,SH3BP4,SLC9A3R1,SNCA,SORL1,SPIDR,SREBF1,STAT1,STXBP4,SULT1A4,UROS |
| GO_MONOVALENT_INORGANIC_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 1125 | 537 | 38 | ADORA1,ADRB2,ANK3,ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATPSCKMT,COMMD3,CYB5A,FGF12,GPD1L,KCNJ1,MFSD3,MT-CO2,PKP2,PTK2B,RNF207,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC36A1,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SURF1,TMEM175,TPCN1,TWIST1,WWP2,YWHAH |
| GO_ALCOHOL_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 377 | 31 | ADH4,ALDH3A2,ASAH2,BCO1,CHKA,CLCN2,CYP2R1,DGAT2,ELOVL6,ERLIN2,GBA2,GDE1,IDH2,INPP4A,ITPK1,LDLRAP1,LIPE,MINPP1,NR1H4,NUDT11,PLCB2,PLCD3,PLPP6,PMVK,PTK2B,SCAP,SCARB1,SNCA,SREBF1,SULT1A4,TM7SF2 |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 562 | 39 | ADIPOQ,APBB1,CDON,CRTC1,DISC1,DLG4,ENC1,FBXW8,FN1,FZD1,FZD3,FZD4,GDPD5,GLI2,GLI3,HIF1A,HMG20B,ITGA3,LIG4,LIMK1,LPAR1,LRRC7,MAP3K13,METRN,NIN,NPTN,PLXND1,PRKCH,PTK2B,ROBO2,SCN1B,SEMA5A,SERPINI1,SMARCD3,STK11,TENM3,TIAM1,TRIM58,ZNF365 |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1125 | 1864 | 85 | ANK3,APBB1,APPL1,ARL3,ARPP19,ASAH2,BCR,C6orf89,CABLES2,CBX5,CCNJL,CCNYL1,CDC14B,CEP68,CHMP7,CRADD,CROCC,CTC1,DIS3L2,ERCC2,ERCC4,FOXN3,FZD3,GAS2L1,GAS6,GDPD5,GJA1,GSPT2,HMG20B,HSPA2,ID1,IK,KIF3A,KLHL13,KLHL9,KLLN,LFNG,LIG4,LLGL1,LLGL2,LMNA,LRP5,MAP10,MAPRE2,MARF1,MARVELD1,MEN1,MICAL3,MYH10,NEK9,NIN,NSL1,NUDT16,NUDT6,NUPR2,PARD6A,PBX1,PKIA,PLAAT3,PPP1R9B,PRKACA,PRKCA,PTCH1,RASSF4,RGCC,RNF212,ROCK2,RPS6KA2,RRAGA,SEPTIN1,SEPTIN5,SLC9A3R1,SLX4,SMARCD3,SPIRE2,STK11,STXBP4,SUN1,TAOK2,TMEM8B,TPD52L1,TTC19,TUBG2,UHMK1,USP2 |
| GO_COENZYME_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1125 | 254 | 25 | ACSM2B,BTD,COQ8B,CROT,CYB5A,DGAT2,DHFR2,ELOVL6,FAR2,GPHN,HLCS,HSD17B8,IDH2,MAT2A,MAT2B,MLYCD,MOCS1,MOCS3,MPC1,MRI1,MTHFR,NUDT7,PMVK,SLC46A1,SNCA |
| GO_HEART_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1125 | 589 | 40 | ARRB2,BASP1,BVES,CCM2,CXADR,EFNB2,ERBB4,FAT4,FGF12,FGFRL1,FZD1,GALNT11,GJA1,GJC1,GLI2,GLI3,HEG1,HIF1A,ID1,ITGA3,JARID2,LMNA,LUZP1,MYH10,PKP2,PLXND1,PPARA,PRICKLE1,PTCD2,PTCH1,RNF207,ROBO2,ROCK2,SMAD6,SMARCD3,SOX18,TGFBR2,TWIST1,WNT11,XIRP2 |
| GO_EXOCYTOSIS | 0.0e+00 | 0.0e+00 | 1125 | 900 | 52 | ACPP,ADAM10,ADCY1,AP2A2,ATP6V0A1,BCR,CD9,COMMD3,EXOC2,EXOC3L1,F8,FN1,GAS6,GHDC,GM2A,HABP4,IQGAP2,JUP,LGALS3BP,LILRB3,LLGL1,LLGL2,LRRC7,MICAL3,MVP,MYH10,NBEAL2,P2RX1,PCDH7,PCYOX1L,PECAM1,PHACTR2,PPFIA3,PRSS12,PYGB,RAB11FIP1,RAB26,RAB3A,RAB3D,RAPGEF4,SEPTIN1,SEPTIN5,SERPING1,SNAP47,SNCA,SNX19,STXBP1,TRAPPC1,UNC13B,VCL,VPS18,ZP3 |
| GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 1125 | 447 | 34 | ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,BCR,CCDC125,CDC42EP3,CYTH3,F2RL2,HEG1,IQSEC1,ITGA3,LIMK1,LPAR1,MAPRE2,MCF2,PECAM1,PRAG1,PSD3,RAB26,RAB3A,RAB3D,RAB4A,RAB7B,RASA4,RHOBTB1,ROCK2,RTN4R,SHC2,SPRY3,STMN3,SYNJ2BP,TIAM1,VAV3 |
| GO_REGULATION_OF_OSSIFICATION | 0.0e+00 | 0.0e+00 | 1125 | 200 | 22 | ADRB2,CITED1,CTNNBIP1,ENPP1,FAM20C,GLI3,HIF1A,ID1,LRP5,MEN1,PBX1,PRKACA,PTCH1,PTK2B,RFLNB,SKI,SMAD6,SMOC1,SOST,TFAP2A,TWIST1,ZHX3 |
| GO_CELLULAR_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1125 | 963 | 54 | ADORA1,ARRB1,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,BDKRB2,CHRNA9,CLDN16,CLN5,DGAT2,DISC1,DLG4,DMXL2,ENPP1,ESR1,F2RL2,FITM2,FOXO1,GAS6,GJA1,GPLD1,GPR157,HIF1A,LPAR1,LRP5,MEN1,NPTN,NR1H4,P2RX1,PLCB2,PLCD3,PRKACA,PTK2B,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,STIM2,STXBP4,TIAM1,TMEM175,TPCN1,TRIM6,TXNRD3,UNC13B |
| GO_NEURON_PROJECTION_GUIDANCE | 0.0e+00 | 1.0e-07 | 1125 | 282 | 26 | AGRN,BCL11B,CRPPA,EFNB2,EPHA7,EVL,FZD3,GLI2,GLI3,KIF3A,LAMA1,MYH10,NPTN,NRTN,PLXND1,PRKCA,PTCH1,PTPRM,ROBO2,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,ZSWIM5 |
| GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 1.0e-07 | 1125 | 302 | 27 | ADAM10,DISC1,DNM3,EPHA7,FBXW8,FN1,ID1,ITGB1BP1,LIMK1,MAP3K13,MCF2,METRN,NIN,PLXND1,ROBO2,RTN4R,SARM1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,STK11,TIAM1,TRAK2,YWHAH,ZSWIM5 |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 0.0e+00 | 1.0e-07 | 1125 | 704 | 44 | ADCY1,ADCY9,ADIPOQ,AGRN,APPL1,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,BBS2,CASP9,CHRM3,ENPP1,ESR1,FOXO1,FOXP1,GAS2L1,GJA1,GNRHR2,GPLD1,IGFBP7,IRS1,KLF9,LGR4,LMO2,LPL,MEN1,NR1H4,PAQR8,PDE3B,PPARA,PPP1R9B,PRKACA,ROBO2,ROCK2,SESN3,SMYD3,SORL1,SOST,SREBF1,STAT1,STXBP4,YWHAH |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 1.0e-07 | 1125 | 944 | 53 | ABHD17A,ADAM10,AMACR,APPL1,ARL3,BBS2,C12orf66,CARD10,CEP68,CHMP7,COG7,CRAT,CROCC,CROT,DISC1,DLG4,DNM3,EFNB2,ESR1,GAS2L1,GGA3,GLI3,GPHN,GSTK1,HYAL2,IK,IMMP2L,JUP,LMNA,LRRC7,MAPRE2,MLYCD,NUDT7,PARD6A,PEX1,PEX2,PEX7,PKIA,PPP1R9B,PRICKLE1,RANBP6,RASSF5,ROCK2,SH3BP4,SNX10,SORL1,SPIDR,SREBF1,STK11,SUN1,TRAM1L1,TRAM2,YWHAH |
| GO_CELL_GROWTH | 0.0e+00 | 1.0e-07 | 1125 | 483 | 35 | ADAM10,APBB1,BRAT1,CCDC85B,DCBLD2,DISC1,ENPP1,EPHA7,FN1,GJA1,HYAL2,IGFBP7,LIMK1,MAP3K13,NIN,PPARA,PPP1R9B,PTK2B,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SGK1,SH3BP4,SLC9A6,SPOCK1,STK11,TAOK2,TGFBR2,TIAM1,UCN,VCL,WNT11 |
| GO_SYNAPTIC_SIGNALING | 0.0e+00 | 1.0e-07 | 1125 | 733 | 45 | ADCY1,ADIPOQ,ADORA1,ADRB2,AGRN,ARRB2,BCHE,BCR,CDH8,CHRM3,CHRNA9,CHRNE,CRTC1,DISC1,DLG4,FGF12,GJC1,GLRB,HTR1D,MINK1,MPP2,NOVA1,NPTN,P2RX1,PCDH17,PCDHB2,PICK1,PPFIA3,PPP1R9B,PRKACA,PTK2B,RAB26,RAB3A,SEPTIN5,SLC12A5,SNAP47,SNCA,SORCS2,STXBP1,SYNJ2BP,TMOD2,UCN,UNC13B,VPS18,YWHAH |
| GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 1125 | 107 | 16 | ADAM10,ARRB1,GALNT11,GDPD5,HIF1AN,ITGB1BP1,JAG2,LFNG,LLGL1,LLGL2,POGLUT1,PRAG1,ROBO2,SLC35C1,SYNJ2BP,WWP2 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1125 | 1267 | 64 | ADCK1,ADRB2,ARHGAP28,ARHGEF19,ARRB1,ARRB2,ASAP3,ATF7IP,C6orf89,CAPZA2,CDC14B,CDC42EP3,CROCC,CTC1,DIXDC1,ERCC4,EVI5L,EVL,FYCO1,GAS2L1,GBA2,GRHL3,H1-0,HIF1A,ID1,IK,IQGAP2,ITGB1BP1,JARID2,KDR,LIG4,LIMK1,LMNA,LPAR1,LRP5,MAPRE2,MTHFR,NBDY,NIN,PICK1,PPM1E,PPP1R9B,PTK2B,RAB3A,RGCC,RHOBTB1,ROCK2,SEMA5A,SKI,SLX4,SNCA,SPIRE2,SREBF1,STMN3,STXBP1,TAOK2,TMEM14A,TMOD2,TWIST1,UCN,VPS18,WNT11,YLPM1,YWHAH |
| GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 1.0e-07 | 1125 | 289 | 26 | APBB1,CRTC1,DISC1,DLG4,ENC1,FBXW8,FN1,FZD1,FZD4,ITGA3,LIMK1,LPAR1,LRRC7,MAP3K13,METRN,NIN,NPTN,PLXND1,PTK2B,ROBO2,SCN1B,SEMA5A,SERPINI1,STK11,TENM3,TIAM1 |
| GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 1.0e-07 | 1125 | 310 | 27 | DIXDC1,DNM3,EFNB2,EPHA7,ERBB4,GDF11,GLI3,ID1,IDH2,LPAR1,MCF2,PBX1,PRAG1,PRKACA,ROBO2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SKI,SORL1,SPOCK1,TRAK2,YWHAH,ZNF365 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 1.0e-07 | 1125 | 823 | 48 | ADIPOQ,ARPP19,ARRB1,ARRB2,ATP7A,CAMK2N2,COL28A1,CSRNP3,DLG3,DUSP22,ELFN2,GAS6,GPSM1,HEG1,HYAL2,INKA2,IQGAP2,ITGB1BP1,KLRC4-KLRK1,LIMK1,LRP5,MARF1,MEN1,MVP,PHACTR2,PKIA,PPM1E,PPP1R9B,PPP2R5A,RAG1,RASA4,RECK,ROCK2,SERPINB13,SERPING1,SERPINI1,SH3BP4,SMYD3,SNCA,SORL1,SORT1,SPINT2,SPOCK1,SPRY3,STK38,TNFSF14,TNK2,ZFYVE28 |
| GO_REGULATION_OF_TRANSPORTER_ACTIVITY | 0.0e+00 | 1.0e-07 | 1125 | 290 | 26 | ADRB2,ANK3,ATP7A,ATPSCKMT,DLG3,DLG4,FGF12,GJA1,GNB5,GOPC,GPD1L,HSPA2,LRRC7,MINK1,PRKACA,PTK2B,RNF207,SCN1B,SGK1,SLC9A3R1,SNCA,STIM2,TCAF1,TWIST1,WWP2,YWHAH |
| GO_ORGANIC_ANION_TRANSPORT | 0.0e+00 | 1.0e-07 | 1125 | 492 | 35 | ABCD3,ADORA1,ATP8B1,ATP8B3,BDKRB2,CPTP,CROT,GJA1,MPC1,NR1H4,PCTP,PITPNC1,PLA2G12A,PLA2G2C,PPARA,PPFIA3,PRAF2,RAB3A,SCARB1,SLC16A12,SLC25A12,SLC25A18,SLC25A23,SLC25A29,SLC25A42,SLC35A1,SLC36A1,SLC46A1,SLC4A4,SLC51A,SLC9A3R1,SNCA,STXBP1,TNFRSF11A,UNC13B |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 1.0e-07 | 1125 | 469 | 34 | ADIPOQ,ARRB1,ARRB2,BDKRB2,CAMK2N2,CHRNA9,DUSP22,ENPP1,FOXO1,GPD1L,HEG1,HYAL2,INKA2,ITGB1BP1,LRP5,MEN1,MVP,PARD6A,PKIA,PPARA,PPM1E,PPP2R5A,PTPN13,SIRT3,SLC9A3R1,SMAD6,SMYD3,SNCA,SORL1,SPRY3,STK38,SYNJ2BP,TWIST1,ZFYVE28 |
| GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM | 0.0e+00 | 1.0e-07 | 1125 | 141 | 18 | AP2A2,ARHGEF19,ARRB2,CELSR2,DLG3,FZD1,FZD3,FZD4,GRHL3,LAMA1,LAMA5,PARD6A,PRICKLE1,PRICKLE2,SLC9A3R1,TIAM1,VANGL1,WNT11 |
| GO_REPRODUCTION | 0.0e+00 | 1.0e-07 | 1125 | 1457 | 70 | ADAM10,ANTXR1,ARMC2,ARRB1,ARRB2,ATP8B3,BASP1,BBS2,C11orf74,CD9,CFAP44,CITED1,CXADR,ERCC4,ESR1,ETNK2,FBXW8,FSTL3,FZD4,GJA1,GJB5,GLI2,GLI3,GLRB,HIF1A,HSPA2,HTRA1,IFT81,IGFBP7,IMMP2L,ITGA3,JAG2,LFNG,LGR4,MAMLD1,MARF1,MEIG1,MEN1,OR1D2,P2RX1,PAPPA,PAQR8,PBX1,PICK1,PLCD3,PPP1R9B,PRKACA,PTCH1,PTK2B,RAB3A,RECK,RNF212,ROBO2,SLX4,SPINT2,SPIRE2,STK11,STXBP1,SULF1,SUN1,TCFL5,TGFBR2,TTLL1,TUBG2,TXNRD3,UCN,UNC13B,VGF,ZFP41,ZP3 |
| GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 1.0e-07 | 1125 | 378 | 30 | APBB1,CDON,CRTC1,DISC1,DLG4,ENC1,FBXW8,FN1,FZD1,FZD4,GDPD5,GLI2,HMG20B,ITGA3,LIMK1,LPAR1,LRRC7,MAP3K13,METRN,NIN,NPTN,PLXND1,PTK2B,ROBO2,SCN1B,SEMA5A,SERPINI1,STK11,TENM3,TIAM1 |
| GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 1125 | 194 | 21 | B4GAT1,CHST12,CHST2,CHST7,CHSY3,CSAD,ELOVL6,GLCE,GSTA4,GSTK1,HSD17B8,MAT2A,MAT2B,MLYCD,MPC1,MRI1,MTHFR,NDST3,PAPSS1,SNCA,XYLT2 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1125 | 337 | 28 | DIXDC1,DNM3,EFNB2,EPHA7,ERBB4,GDF11,GLI3,ID1,IDH2,ITGB1BP1,LPAR1,MCF2,PBX1,PPARA,PRAG1,RFLNB,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SKI,SORL1,SPOCK1,TRAK2,YWHAH,ZNF365 |
| GO_REGULATION_OF_BINDING | 0.0e+00 | 2.0e-07 | 1125 | 381 | 30 | ADIPOQ,ADRB2,ARHGAP28,ARRB1,ARRB2,CDON,CLN5,CTNNBIP1,DISC1,ERCC2,ERCC4,FBH1,GPSM1,H1-0,HABP4,ID1,IRF4,ITGB1BP1,LDLRAP1,LFNG,MEN1,PLXND1,PPARA,PRKACA,SKI,SMARCD3,SORL1,TIAM1,TRIM6,TWIST1 |
| GO_MUSCLE_STRUCTURE_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1125 | 673 | 42 | ARRB2,BASP1,BCL9L,BVES,CD9,CDON,CSRP1,CXADR,EFNB2,ERBB4,FGFRL1,FZD1,GJA1,HEG1,HIF1AN,HLF,HMG20B,IL18,JARID2,LAMA5,LMNA,MAP3K5,MRTFB,MYEF2,MYH10,MYORG,PKP2,PPARA,PRICKLE1,PTCD2,SKI,SMARCD3,SMYD3,SORT1,TANC1,TGFBR2,TMOD2,TNFSF14,TWIST1,USP2,XIRP2,ZBTB42 |
| GO_REGULATION_OF_HORMONE_LEVELS | 0.0e+00 | 2.0e-07 | 1125 | 524 | 36 | ADH4,ADIPOQ,ADORA1,ARRB1,BCO1,BCO2,CLCN2,CYP2R1,DGAT2,ENPEP,ESR1,EXOC3L1,FZD4,GJA1,GPLD1,HIF1A,HSD17B8,IRS1,LRP5,NR1H4,PCSK1,PFKFB2,PRKCA,RAB11FIP1,RAPGEF4,SCARB1,SIRT3,SNX19,SREBF1,STXBP4,TG,TIAM1,TM7SF3,UCN,VGF,YWHAH |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 2.0e-07 | 1125 | 974 | 53 | ADIPOQ,ADORA1,ADRB2,ARRB1,ARRB2,CCM2,CDON,CHRNA9,DLG3,DLG4,DUSP22,EPHA7,ERBB4,FGF5,FN1,FOXO1,FZD4,GAS6,GDF11,HYAL2,ID1,IL18,IRS1,ITGB1BP1,JCAD,KDR,LPAR1,LRRC7,MAGI3,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,NPTN,NRTN,PRKCA,PTK2B,RASA4,ROCK2,SH3RF3,SHC2,SIRT3,SLC9A3R1,SORL1,SPRY3,STK38,SULT1A4,SYNJ2BP,TAOK2,TIAM1,TNFRSF11A,TPD52L1 |
| GO_BIOMINERALIZATION | 0.0e+00 | 2.0e-07 | 1125 | 162 | 19 | ADRB2,ENPP1,ERCC2,FAM20C,FOXO1,GAS6,HIF1A,ITGB1BP1,LGR4,MINPP1,ODAPH,PPARA,PTK2B,RFLNB,ROCK2,SNX10,TFAP2A,TWIST1,WNT11 |
| GO_POSITIVE_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1125 | 145 | 18 | ABCD2,ADIPOQ,ARPP19,DGAT2,FOXO1,GPLD1,HIF1A,IRS1,LDLRAP1,MLYCD,MT-CO2,NR1H4,PFKFB2,PPARA,SLC25A12,SNCA,SREBF1,TWIST1 |
| GO_TAXIS | 0.0e+00 | 2.0e-07 | 1125 | 652 | 41 | ADAM10,AGRN,ARRB2,BCL11B,CRPPA,CXADR,EFNB2,EPHA7,EVL,FZD3,GAS6,GLI2,GLI3,KDR,KIF3A,KLRC4-KLRK1,LAMA1,LPAR1,MYH10,NPTN,NRTN,OR1D2,PLXND1,PRKCA,PTCH1,PTK2B,PTPRM,ROBO2,SAA2,SCN1B,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TIAM1,TNFRSF11A,TNFSF14,TYMP,VAV3,ZSWIM5 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1125 | 627 | 40 | ACPP,ACSM2B,ADCY1,ADCY9,ATP5F1D,ATPSCKMT,BPNT1,CDS1,CROT,DGAT2,DHFR2,DHTKD1,ELOVL6,ENPP1,ENTPD8,FAR2,GMPR,HIF1A,HSD17B8,IDH2,LHPP,MAGI3,MLYCD,MPC1,MT-CO2,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,NUP210,PAPSS1,PFKFB2,PMVK,PPARA,SLC25A12,SNCA,SULT1A4,TYMP,UXS1 |
| GO_SIGNAL_RELEASE | 0.0e+00 | 2.0e-07 | 1125 | 458 | 33 | ADCY1,ADIPOQ,ADORA1,ARRB1,EXOC3L1,FZD4,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,P2RX1,PFKFB2,PPFIA3,PRKCA,RAB11FIP1,RAB3A,RAPGEF4,SEPTIN5,SIRT3,SNAP47,SNCA,SNX19,SREBF1,STXBP1,STXBP4,TIAM1,TM7SF3,UCN,UNC13B,VGF,VPS18 |
| GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS | 0.0e+00 | 2.0e-07 | 1125 | 483 | 34 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB1,ADRB2,BBS10,BBS2,CROCC,CRTC1,CXADR,ELOVL6,FOXO1,GJA1,GRHL3,HYAL2,ID1,IL18,IRF4,LGR4,MRAP2,MUC2,NOVA1,NOVA2,PCTP,PRKACA,PRKCA,PTK2B,RAB3D,SCNN1A,SCNN1G,SNX10,STK11,TNFRSF11A |
| GO_GLYCEROLIPID_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1125 | 414 | 31 | ACP6,ALDH5A1,BPNT1,CDS1,CHKA,DGAT2,EFR3A,ETNK2,FITM2,GDE1,GPD1L,GPLD1,INPP4A,LIPE,LPCAT3,LPCAT4,LPL,NR1H4,PCTP,PIGM,PIGN,PIGX,PLA2G12A,PLAAT3,PTPN13,RAB4A,SCARB1,SLC44A1,SORL1,SREBF1,ZP3 |
| GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 3.0e-07 | 1125 | 184 | 20 | DNM3,EFNB2,EPHA7,EVI5L,EVL,ID1,ITGA3,LPAR1,MCF2,PRAG1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SPOCK1,TRAK2,YWHAH,ZNF365 |
| GO_REGULATION_OF_AXONOGENESIS | 0.0e+00 | 3.0e-07 | 1125 | 184 | 20 | DISC1,EPHA7,FN1,LIMK1,MAP3K13,MCF2,METRN,NIN,PLXND1,ROBO2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,STK11,TIAM1,TRAK2,ZSWIM5 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 3.0e-07 | 1125 | 1247 | 62 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,ARRB2,ATG10,BRAT1,C6orf89,CARD10,CCNYL1,CDC14B,CDON,DLG3,DLG4,DUSP22,EPHA7,ERBB4,FBH1,FZD1,FZD4,GAS6,GDF11,HSPA2,IL18,ITGB1BP1,JARID2,JCAD,KDR,LMNA,LPAR1,MAP3K13,MAP3K5,MAP4K2,MINK1,NPTN,NSMCE3,PECAM1,PPP2R5A,PRICKLE1,PRKACA,PRKCA,PTK2B,RASSF5,RGCC,ROCK2,SH3RF3,SHC2,SMYD3,SNCA,SREBF1,STK11,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TNK2,TPD52L1,TRIM6,UCN,WNT11 |
| GO_CHROMATIN_ORGANIZATION | 0.0e+00 | 3.0e-07 | 1125 | 795 | 46 | ACTR5,APBB1,ARRB1,ASH2L,ATF7IP,BRD3,C6orf89,CBX6,CBX7,DPF1,ESR1,EYA4,H1-0,H2AC11,H2AC6,H2AJ,H2AW,H2BC4,H3C10,H3C12,H4C9,HLCS,HMG20B,HR,IRF4,JARID2,LMNA,MEN1,MTHFR,NAP1L3,NAP1L5,NR1H4,PRKCA,RAG1,SATB1,SIRT3,SKI,SMARCD3,SMYD3,SNCA,SREBF1,SUPT4H1,TSPYL1,TWIST1,UCN,ZMIZ2 |
| GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 3.0e-07 | 1125 | 167 | 19 | CDH12,CDH17,CDH18,CDH7,CDH8,CELSR2,FAT1,FAT4,NPTN,PCDH17,PCDH18,PCDH7,PCDHA3,PCDHB2,PCDHGB4,PECAM1,PTPRM,ROBO2,TENM3 |
| GO_METAL_ION_TRANSPORT | 0.0e+00 | 3.0e-07 | 1125 | 906 | 50 | ADORA1,ADRB2,ANK3,ARRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,CCS,CHRNA9,CLDN16,COMMD3,FGF12,GAS6,GJA1,GNB5,GPD1L,HSPA2,KCNJ1,MRS2,P2RX1,PKP2,PLCB2,PLCD3,PRKACA,PTK2B,RNF207,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,SPG7,STIM2,TMEM175,TMEM37,TPCN1,UCN,WWP2,YWHAH |
| GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 3.0e-07 | 1125 | 204 | 21 | ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,BCR,CCDC125,CDC42EP3,F2RL2,HEG1,ITGA3,LIMK1,LPAR1,MCF2,PECAM1,PRAG1,RHOBTB1,ROCK2,RTN4R,SYNJ2BP,TIAM1,VAV3 |
| GO_NEGATIVE_REGULATION_OF_CELL_MOTILITY | 0.0e+00 | 3.0e-07 | 1125 | 350 | 28 | ADIPOQ,ADORA1,BCR,CARD10,CCDC125,CD200,DUSP22,ERBB4,EVL,FRMD5,GJA1,HYAL2,IDH2,ITGB1BP1,JUP,KLRC4-KLRK1,PTPRM,RECK,RGCC,SEMA6D,SLC9A3R1,SPINT2,SRGAP1,SULF1,SYNJ2BP,TCAF1,VCL,WNT11 |
| GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM | 0.0e+00 | 3.0e-07 | 1125 | 151 | 18 | FZD1,FZD3,GLI2,GRHL3,HIF1A,IRX2,JAG2,LAMA5,LUZP1,MTHFR,PRICKLE1,PRKACA,PTCH1,SKI,SPINT2,SULF1,TFAP2A,TWIST1 |
| GO_AMMONIUM_ION_METABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1125 | 206 | 21 | ALDH7A1,ASAH2,ATP7A,BCHE,CDS1,CHKA,CRAT,CROT,GPLD1,LPCAT3,LPCAT4,MAOB,PCTP,PLA2G12A,PLAAT3,SCARB1,SGMS1,SLC44A1,SNCA,SPTLC3,SULT1A4 |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 4.0e-07 | 1125 | 669 | 41 | ARHGAP28,ARRB1,ASAP3,ATP7A,CAPZA2,CDC42EP3,CSRP1,EVL,FAT1,FHDC1,GBA2,GFAP,HIP1,ID1,IQGAP2,ITGB1BP1,KATNAL2,LIMK1,LPAR1,MAP10,MARCKS,MICAL3,MYH10,NIN,PICK1,PKP2,PPM1E,PPP1R9B,PTK2B,RFLNB,RGCC,RHOBTB1,ROCK2,SEMA5A,SERF1B,SNCA,SPIRE2,STMN3,TMOD2,TUBG2,WNT11 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 4.0e-07 | 1125 | 1026 | 54 | ADIPOQ,ADORA1,ADRB2,AGO1,ARRB1,ARRB2,C1QTNF4,CARD10,CDON,DUSP22,ERBB4,ESR1,F2RL2,FBH1,FGF5,FZD4,GAS6,GJA1,HIP1,IL18,IRS1,ITGB1BP1,JCAD,KDR,LPAR1,MAP3K13,MAP3K5,MAP4K2,MAPRE2,MEIS3,MINK1,MRAP2,MYORG,NPTN,PRAG1,PRKCA,PTK2B,ROCK2,RRAGA,RTN4R,S100A4,SEMA5A,SH3RF3,SHC2,SLC9A3R1,TAOK2,TIAM1,TNFRSF11A,TNFSF14,TPD52L1,TRIM44,TSPAN6,UCN,WNT11 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 4.0e-07 | 1125 | 620 | 39 | ADIPOQ,ALDH5A1,ARPP19,B3GALT1,BRAT1,CHST12,CHST2,CHST7,CRYL1,CYB5A,DGAT2,DHTKD1,ENPP1,FOXO1,FPGT,GALNT7,GDPGP1,GM2A,GPD1L,GPLD1,H6PD,HEXD,HIF1A,HYAL2,IDH2,IRS1,ITPK1,LRP5,MLYCD,MYORG,NDST3,NUP210,PFKFB2,PPARA,PTK2B,PYGB,SLC25A12,SLC35A1,SNCA |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 4.0e-07 | 1125 | 423 | 31 | ACSM2B,ADCY1,ADCY9,ATP5F1D,ATPSCKMT,BPNT1,CROT,DGAT2,DHTKD1,ELOVL6,ENPP1,FAR2,GMPR,HIF1A,HSD17B8,MAGI3,MLYCD,MPC1,MT-CO2,NUDT11,NUDT16,NUDT18,NUDT7,NUP210,PAPSS1,PFKFB2,PMVK,PPARA,SLC25A12,SNCA,SULT1A4 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 0.0e+00 | 5.0e-07 | 1125 | 292 | 25 | BCL9L,CITED1,FAM20C,FGFBP3,FSTL3,FZD1,FZD4,HIF1A,HTRA1,ITGA3,JCAD,MEN1,NPTN,NREP,PEG10,SKI,SKOR1,SLC9A6,SMAD6,SORL1,SOST,SPRY3,STK11,SULF1,TGFBR2 |
| GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 5.0e-07 | 1125 | 251 | 23 | ACP6,CDS1,CHKA,DGAT2,ETNK2,FITM2,GPD1L,GPLD1,INPP4A,LPCAT4,LPL,NR1H4,PCTP,PIGM,PIGN,PIGX,PLA2G12A,PTPN13,RAB4A,SCARB1,SLC44A1,SREBF1,ZP3 |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 5.0e-07 | 1125 | 1124 | 57 | ABCD2,ADAM10,ADIPOQ,ADORA1,APPL1,ARRB2,BBS2,BCR,CD200,CD9,EFNB2,ESR1,FOXP1,GAS6,GJA1,HTRA1,HYAL2,IFNAR2,IL18,IRF4,KDR,KLRC4-KLRK1,LGR4,LPAR1,LPL,MUC2,NLRP1,NR1H4,PPARA,PPEF1,PRKACA,PRKCA,PTK2B,RAB7B,ROBO2,RTN4R,SARM1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SERPING1,SNCA,STAT1,TGFBR2,TIAM1,TNFRSF11A,TNFSF14,TRIM44,TRIM6,TSPAN6,UCN,UNC13B,UNC93B1,ZP3,ZSWIM5 |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 6.0e-07 | 1125 | 655 | 40 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,ATPSCKMT,CARD10,CCNYL1,CD200,CDC14B,DLG3,DLG4,FZD4,GAS6,IL18,IRS1,ITGB1BP1,LPAR1,MAP3K13,MAP3K5,MAP4K2,MINK1,PARM1,PFKFB2,PRKACA,PTK2B,RGCC,SHC2,SNCA,SORL1,STK11,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,UCN,VAV3,WNT11 |
| GO_TISSUE_MIGRATION | 0.0e+00 | 6.0e-07 | 1125 | 363 | 28 | CARD10,EFNB2,EPB41L4B,EVL,FOXP1,GPLD1,HIF1A,ID1,IQSEC1,ITGA3,ITGB1BP1,JCAD,JUP,KDR,MAPRE2,PECAM1,PLXND1,PRKCA,PRKX,PTK2B,PTPRM,RGCC,ROCK2,SCARB1,SEMA5A,SOX18,SYNJ2BP,TGFBR2 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 7.0e-07 | 1125 | 532 | 35 | ADH4,ADIPOQ,ALDH4A1,ALDH5A1,ATP5F1D,ATP7A,ATPSCKMT,CROT,CYB5A,DHTKD1,ENPP1,ETFDH,H6PD,HIF1A,IDH2,IMMP2L,IRS1,MAOB,MRAP2,MT-CO2,NDUFB3,NUP210,PFKFB2,PPARA,PYGB,RUNX1T1,SIRT3,SLC25A12,SLC25A18,SLC25A23,SNCA,SURF1,TXNRD3,UCN,VGF |
| GO_PEPTIDYL_SERINE_MODIFICATION | 0.0e+00 | 7.0e-07 | 1125 | 319 | 26 | ARRB1,ARRB2,BDKRB2,GALNT1,GALNT2,GAS6,GPD1L,MAP3K13,MAST3,MGAT5B,POGLUT1,POGLUT3,PRKACA,PRKCA,PRKCH,PRKX,ROCK2,SGK1,SMYD3,SNCA,STK32A,STK38,TGFBR2,TRIM6,UCN,UHMK1 |
| GO_PROTEOLYSIS | 0.0e+00 | 7.0e-07 | 1125 | 1779 | 78 | ACTR5,ADAM10,ADAM32,ADRB2,ANKIB1,ANTXR1,ARRB1,ARRB2,C17orf97,CASP9,CFI,CLN5,COL28A1,CRADD,DISC1,ENC1,ENPEP,EPHA7,ERLIN2,ESR1,F8A1,F8A3,FBXL16,FBXL4,FBXO21,FBXO33,FBXW8,FN1,GAS6,GLI3,GPLD1,HECTD3,HIF1A,HIP1,HTRA1,IMMP2L,LDLRAD3,MAGEF1,MAP3K5,NLRP1,NLRP2,NRIP2,NUDT16,P2RX1,PAPPA,PCSK1,PCYOX1L,PREP,PRICKLE1,PRKACA,PRSS12,PTCH1,PTK2B,RAG1,RECK,RMND5B,RNF123,RNFT1,ROCK2,SCRN3,SENP8,SERPINB13,SERPING1,SERPINI1,SNCA,SORL1,SPG7,SPINT2,SPOCK1,TMTC3,TNFSF14,TRIM58,UBE2D4,UBE2L6,USP2,USP48,VSIR,WWP2 |
| GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 7.0e-07 | 1125 | 387 | 29 | ADORA1,ARHGAP28,ARHGEF19,ASAP3,CAPZA2,CDC42EP3,DIXDC1,EVL,GBA2,GRHL3,ID1,IQGAP2,ITGB1BP1,JUP,LIMK1,LPAR1,PICK1,PKP2,PPM1E,PTK2B,RGCC,RHOBTB1,RNF207,ROCK2,SEMA5A,SPIRE2,TAOK2,TMOD2,WNT11 |
| GO_ACID_SECRETION | 0.0e+00 | 7.0e-07 | 1125 | 125 | 16 | ADORA1,BDKRB2,GJA1,PLA2G12A,PLA2G2C,PPFIA3,RAB3A,SGK1,SLC51A,SLC9A3R1,SNCA,SNX10,STXBP1,TNFRSF11A,UCN,UNC13B |
| GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION | 0.0e+00 | 7.0e-07 | 1125 | 159 | 18 | ARHGAP28,ARRB1,ASAP3,EVL,FHDC1,ID1,ITGB1BP1,LIMK1,LPAR1,MARCKS,PPM1E,PTK2B,RFLNB,RGCC,RHOBTB1,ROCK2,SPIRE2,WNT11 |
| GO_PROTON_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 7.0e-07 | 1125 | 159 | 18 | ATP5F1D,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATPSCKMT,CYB5A,MFSD3,MT-CO2,SLC36A1,SLC46A1,SLC9A3R1,SLC9A6,SLC9A7,SURF1,TWIST1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 8.0e-07 | 1125 | 366 | 28 | ABCD2,ADRB2,ANKIB1,DISC1,FBXW8,FOXO1,FYCO1,GPLD1,GPSM1,HIF1A,IRS1,KDR,MAGEF1,PFKFB2,PPARA,PRICKLE1,PTK2B,RNFT1,ROCK2,SCOC,SESN3,SH3BP4,SNCA,STK11,TMTC3,TNRC6C,TPCN1,TWIST1 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 8.0e-07 | 1125 | 1198 | 59 | ADRB2,AGO1,AGRN,APBB1,ARRB1,ASH2L,BCL11B,BCL9L,BEX1,CDON,CRTC1,CSRNP3,DBP,DPF1,ERCC2,ERLIN2,ESR1,FOXO1,FSTL3,GLI2,GLI3,GRHL3,HELZ2,HIF1A,HLF,HOXD8,HYAL2,IL18,IRF4,ITGB1BP1,JUP,KLF14,LMO2,LRP5,MEIS3,MEN1,MRTFB,NR1H4,PBX1,PLXND1,PPARA,RGCC,SCAP,SKI,SMAD6,SMYD3,SOX13,SOX18,SREBF1,SSBP3,STAT1,SUPT4H1,TFAP2A,THRAP3,TOX2,TWIST1,UCN,WWP2,ZMIZ2 |
| GO_GOLGI_VESICLE_TRANSPORT | 0.0e+00 | 8.0e-07 | 1125 | 367 | 28 | ANK3,ARL3,BBS2,CAPZA2,CCDC91,COG2,COG7,COPG2,CYTH3,DOP1B,EXOC2,F8,GAS6,GGA3,GOPC,KIF3A,LLGL1,PICK1,RAB26,RAB7B,SNX1,SORL1,SORT1,STX17,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 8.0e-07 | 1125 | 1410 | 66 | ABHD13,ABHD17A,AGO1,AGRN,ANKIB1,AP2A2,ARRB1,ARRB2,C17orf97,CARHSP1,CEMIP2,CLN5,DIS3L2,DISC1,DNASE1L2,ENC1,ERLIN2,F8A1,F8A3,FBH1,FBXL16,FBXL4,FBXO21,FBXO33,FBXW8,FOXO1,GFAP,GGA3,GJA1,GPLD1,GSPT2,H1-0,HECTD3,HELZ2,HYAL2,MAGEF1,MYEF2,NAGLU,NBDY,NUDT16,PCYOX1L,PRICKLE1,PRKACA,PRKCA,PTK2B,PYGB,RAB26,RMND5B,RNF123,RNFT1,ROCK2,SDC3,SNCA,SNX1,SORL1,TENT5C,THRAP3,TMTC3,TNRC6C,TRIM58,UBE2D4,UBE2L6,USP2,USP48,WDR91,WWP2 |
| GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 0.0e+00 | 8.0e-07 | 1125 | 237 | 22 | ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,BCR,CCDC125,CYTH3,F2RL2,HEG1,IQSEC1,ITGA3,LPAR1,MAPRE2,MCF2,PRAG1,PSD3,RASA4,RTN4R,SPRY3,STMN3,TIAM1,VAV3 |
| GO_NEPHRON_DEVELOPMENT | 0.0e+00 | 8.0e-07 | 1125 | 143 | 17 | ADIPOQ,BASP1,CITED1,CTNNBIP1,ENPEP,FAT4,GLI3,IRX2,ITGA3,LAMA5,LGR4,PBX1,PECAM1,PTCH1,STAT1,SULF1,WNT11 |
| GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 0.0e+00 | 8.0e-07 | 1125 | 537 | 35 | ARRB1,BBS2,CHMP7,DNM3,F8,F8A1,F8A3,FYCO1,GJA1,GPLD1,HIF1A,KIF3A,LLGL1,LLGL2,LRP5,MAP4K2,NR1H4,PLCB2,PLCD3,PRKACA,PTK2B,RAB3A,SEPTIN5,SLC9A3R1,SNCA,SPIRE2,STXBP4,SUN1,TIAM1,TPCN1,TRAK2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9 |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 8.0e-07 | 1125 | 463 | 32 | ACPP,ACSM2B,ADCY1,ADCY9,ATP5F1D,ATPSCKMT,BPNT1,CROT,DGAT2,DHTKD1,ELOVL6,ENPP1,FAR2,GMPR,HIF1A,HSD17B8,MAGI3,MLYCD,MPC1,MT-CO2,NUDT11,NUDT16,NUDT18,NUDT7,NUP210,PAPSS1,PFKFB2,PMVK,PPARA,SLC25A12,SNCA,SULT1A4 |
| GO_REGULATION_OF_SYSTEM_PROCESS | 0.0e+00 | 8.0e-07 | 1125 | 614 | 38 | ACPP,ADIPOQ,ADORA1,ADRB1,ADRB2,ATPSCKMT,BDKRB2,BVES,CHRM3,CXADR,DLG4,FGF12,FOXO1,GAS6,GJA1,GJC1,GPD1L,HSPB6,JARID2,JUP,LMNA,P2RX1,PKP2,PPARA,PRKACA,PRKCA,PTK2B,RAB11FIP1,RNF207,ROCK2,SCN1B,SGK1,SLC25A12,SLC9A3R1,SREBF1,TYMP,UCN,UNC13B |
| GO_ACTIN_FILAMENT_ORGANIZATION | 0.0e+00 | 9.0e-07 | 1125 | 393 | 29 | ARHGAP28,ARRB1,ASAP3,CAPZA2,CDC42EP3,EVL,FAT1,FHDC1,GBA2,HIP1,ID1,IQGAP2,ITGB1BP1,LIMK1,LPAR1,MARCKS,MICAL3,PICK1,PPM1E,PPP1R9B,PTK2B,RFLNB,RGCC,RHOBTB1,ROCK2,SEMA5A,SPIRE2,TMOD2,WNT11 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 0.0e+00 | 9.0e-07 | 1125 | 111 | 15 | ADRB1,ADRB2,BBS2,EPHA7,GJA1,JARID2,PPARA,PTCH1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TGFBR2 |
| GO_NEGATIVE_REGULATION_OF_OSSIFICATION | 0.0e+00 | 9.0e-07 | 1125 | 81 | 13 | CITED1,ENPP1,HIF1A,ID1,LRP5,MEN1,PTCH1,PTK2B,RFLNB,SKI,SMAD6,SOST,TWIST1 |
| GO_CELL_SUBSTRATE_ADHESION | 0.0e+00 | 9.0e-07 | 1125 | 348 | 27 | AGR2,ANTXR1,BCR,BVES,DISC1,DUSP22,FN1,FZD4,GAS6,ID1,ITGA3,ITGB1BP1,JUP,KDR,LAMA5,MEN1,MINK1,PECAM1,PRKX,PTK2B,ROCK2,SMAD6,SPOCK1,TAOK2,TIAM1,TMEM8B,VCL |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 9.0e-07 | 1125 | 860 | 47 | APBB1,ATF7IP,BACH2,CBX5,CBX6,CBX7,CTNNBIP1,DUSP22,ESR1,FAM220A,FOXO1,GLI2,GLI3,H1-0,HIF1AN,HOXD8,ID1,IRX2,JARID2,JAZF1,MEN1,MYPOP,NR1H4,NUPR2,PCBP3,PEX2,PKIA,PPARA,PTCH1,PURB,SATB1,SKI,SKOR1,SNCA,SOX18,SREBF1,STAT1,SUPT4H1,TCFL5,TFAP2A,TWIST1,USP2,WWP2,ZBTB42,ZBTB45,ZHX3,ZKSCAN3 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 9.0e-07 | 1125 | 973 | 51 | ABCA3,ABCD3,ADCY1,ADIPOQ,ARRB2,BCHE,CASP9,CHKA,CHRM3,CITED1,ESR1,FOXO1,FOXP1,GJA1,GLI2,GNB5,GPLD1,HLCS,HTR1D,ID1,IGFBP7,IL18,JUP,KLF9,MAOB,MTHFR,NR1H4,P2RX1,PAPPA,PAQR8,PMVK,PPARA,PPP1R9B,PRKACA,PTCH1,PTK2B,ROCK2,SLC9A3R1,SMYD3,SNCA,SPIDR,SREBF1,SRR,STAT1,STXBP1,SULT1A4,TGFBR2,TIAM1,UCN,VGF,YWHAH |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 1.0e-06 | 1125 | 567 | 36 | ABLIM1,ABLIM2,AGRN,ARHGEF26,ARHGEF4,ARL3,ARMC2,ATP7A,ATP8B1,BBS10,BBS2,CDC14B,CDC42EP3,CELSR2,CFAP221,CFAP44,CROCC,DISC1,DNM3,EVI5L,EVL,FHDC1,GALNT11,IFT81,KIF3A,LAMA5,LPAR1,MIEN1,MYH10,PPP1R9B,PRKACA,SLC9A3R1,SNX10,TTLL1,VAV3,VCL |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 1.0e-06 | 1125 | 542 | 35 | ADIPOQ,ARRB1,ARRB2,BDKRB2,C12orf66,CCDC125,CHRNA9,ESR1,FOXO1,GPD1L,HEG1,HIF1A,HYAL2,ITGA3,ITGB1BP1,LPAR1,MEN1,MRAP2,NR1H4,PDE3B,RASA4,SESN3,SH3BP4,SIRT3,SLC9A3R1,SORL1,SPRY3,STAT1,STK11,STK38,STMN3,SYNJ2BP,TNFAIP8L1,TSPAN6,TWIST1 |
| GO_ORGANIC_ACID_TRANSPORT | 0.0e+00 | 1.1e-06 | 1125 | 328 | 26 | ABCD3,ADORA1,ATP8B1,BDKRB2,CROT,GJA1,MPC1,NR1H4,PLA2G12A,PLA2G2C,PPARA,PPFIA3,PRAF2,RAB3A,SLC16A12,SLC25A12,SLC25A18,SLC25A29,SLC36A1,SLC46A1,SLC51A,SLC9A3R1,SNCA,STXBP1,TNFRSF11A,UNC13B |
| GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | 0.0e+00 | 1.1e-06 | 1125 | 147 | 17 | ABCD2,ADIPOQ,ADORA1,DGAT2,GPLD1,IRS1,LDLRAP1,MLYCD,NR1H4,PPARA,PTK2B,SCARB1,SIRT3,SREBF1,TWIST1,VAV3,ZP3 |
| GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 1.2e-06 | 1125 | 223 | 21 | DIXDC1,DNM3,EFNB2,EPHA7,GDF11,GLI3,ID1,LPAR1,MCF2,PBX1,PRAG1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SPOCK1,TRAK2,YWHAH,ZNF365 |
| GO_DENDRITE_DEVELOPMENT | 0.0e+00 | 1.2e-06 | 1125 | 244 | 22 | ADAM10,AGRN,CELSR2,CRTC1,DISC1,DLG4,DNM3,FBXW8,ID1,LPAR1,MCF2,MINK1,PPP1R9B,SARM1,SLC12A5,SLC9A6,STK11,TAOK2,TIAM1,TRAK2,YWHAH,ZNF365 |
| GO_DEVELOPMENTAL_GROWTH | 0.0e+00 | 1.2e-06 | 1125 | 677 | 40 | ADRB1,ADRB2,AGR2,AGRN,BASP1,BBS2,CCM2,CD9,CTC1,DISC1,EPHA7,ERBB4,ERCC2,ESR1,ETNK2,FN1,GJA1,GLI2,GLI3,HEG1,JARID2,LIMK1,MAP3K13,NIN,PPARA,PTCH1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC12A5,SLC9A6,STK11,TGFBR2,TIAM1,VCL,WNT11,ZP3 |
| GO_REGULATION_OF_VASCULATURE_DEVELOPMENT | 0.0e+00 | 1.3e-06 | 1125 | 425 | 30 | ADAM10,AGO1,CARD10,CEMIP2,COL4A2,DDAH1,EFNB2,HIF1A,HIF1AN,HSPB6,ID1,ITGB1BP1,JCAD,JUP,KDR,PDE3B,PLXND1,PRKCA,PTK2B,PTPRM,RECK,RGCC,ROCK2,SEMA5A,STAT1,SULF1,SYNJ2BP,TGFBR2,THBS2,TWIST1 |
| GO_SENSORY_ORGAN_DEVELOPMENT | 1.0e-07 | 1.4e-06 | 1125 | 549 | 35 | ADAM10,ATP8B1,BCL11B,BCR,CCM2,CDON,CHRNA9,CLCN2,COL4A1,FAT1,FAT4,FZD3,FZD4,GDF11,GLI2,GLI3,GRHL3,HIF1A,JAG2,LAMA1,LHFPL5,LRP5,MYH10,NAGLU,NHS,PDZD7,PTPRM,SKI,SLC9A3R1,SMARCD3,SMOC1,TENM3,TFAP2A,TGFBR2,TWIST1 |
| GO_RESPONSE_TO_LIPID | 1.0e-07 | 1.4e-06 | 1125 | 930 | 49 | ABCA3,ADCY1,ADIPOQ,ARRB2,BCHE,BCR,CASP9,CITED1,DGAT2,ESR1,FOXO1,FOXP1,FZD4,GJA1,GNG12,GPLD1,IGFBP7,IL18,IRS1,KLF9,KLRC4-KLRK1,LOXL1,LPAR1,LPL,MAOB,NR1H4,PAPPA,PAQR8,PMVK,PPARA,PPP1R9B,PRKCA,PTCH1,PTK2B,ROCK2,SCARB1,SGMS1,SMAD6,SMYD3,SNCA,SREBF1,SRR,STXBP1,TGFBR2,TNFRSF11A,TRIM6,UCN,WNT11,YWHAH |
| GO_RESPONSE_TO_PEPTIDE | 1.0e-07 | 1.4e-06 | 1125 | 525 | 34 | ADCY1,ADCY9,ADIPOQ,ADRB2,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CITED1,ENPP1,FOXO1,GJA1,GNRHR2,GPLD1,ID1,IRS1,LPL,MEN1,NLRP1,NR1H4,PDE3B,PPARA,PPP1R9B,PRKACA,ROCK2,SCAP,SESN3,SORL1,SORT1,SREBF1,STAT1,STXBP4,VGF |
| GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY | 1.0e-07 | 1.5e-06 | 1125 | 150 | 17 | AGO1,AP2A2,ARHGEF19,ARRB2,CELSR2,FZD1,FZD3,FZD4,GRHL3,PARD6A,PLCB2,PRICKLE1,PRICKLE2,TIAM1,TNRC6C,VANGL1,WNT11 |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 1.0e-07 | 1.5e-06 | 1125 | 960 | 50 | ADAM10,ARRB1,ASH2L,ATP7A,CDON,CITED1,CTC1,DISC1,EFNB2,ERBB4,ESR1,FGF5,FN1,FOXP1,FZD3,GAS6,GJA1,GLI2,GLI3,HIF1A,HTRA1,ID1,IL11RA,IL18,IRS1,ITGB1BP1,JCAD,KDR,LDLRAP1,LIFR,LIG4,LRP5,MAP3K5,NUDT16,PBX1,PRKCA,PRKCH,PTK2B,SEMA5A,SMARCD3,SSBP3,STAT1,STXBP4,TBC1D8,TGFBR2,TIAM1,TNFRSF11A,TWIST1,VAV3,ZP3 |
| GO_CELLULAR_ION_HOMEOSTASIS | 1.0e-07 | 1.5e-06 | 1125 | 683 | 40 | ADORA1,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ATP7A,ATP7B,BDKRB2,CHRNA9,CLDN16,CLN5,DISC1,DLG4,DMXL2,ENPP1,ESR1,F2RL2,GJA1,GPR157,HIF1A,LPAR1,NPTN,P2RX1,PLCB2,PLCD3,PRKACA,PTK2B,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SLC4A4,SLC9A3R1,SLC9A6,SLC9A7,SNCA,STIM2,TMEM175,TPCN1 |
| GO_NERVOUS_SYSTEM_PROCESS | 1.0e-07 | 1.6e-06 | 1125 | 1441 | 66 | ABLIM1,ACPP,ADCY1,ADORA1,ADRB2,ALDH7A1,ANK3,ARRB2,ATP8B1,ATPSCKMT,BBS10,BBS2,BCHE,BCR,C1QL1,CHRNA9,CHRNE,CRTC1,CYP4V2,DGCR2,DLG4,DOP1B,EYA4,FGF12,FZD4,GJC1,GLRB,GM2A,GPR155,HERC1,HIF1A,ITGA3,LHFPL5,MPP2,MYH10,NPTN,OR1D2,OR2B6,OR2W3,OR4F17,OR52N1,P2RX1,PDZD7,PLCB2,PPEF1,PPP1R9B,PTK2B,RAB3A,RAG1,REEP2,REEP6,ROCK2,SCN1B,SCNN1A,SCNN1G,SGK1,SLC12A5,SLC25A12,SLC9A3R1,SNCA,TANC1,TFAP2A,TMOD2,TYMP,UCN,UNC13B |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 1.0e-07 | 1.7e-06 | 1125 | 406 | 29 | BBS2,CHMP7,COPG2,CROCC,DNM3,F8,F8A1,F8A3,FYCO1,GJA1,HIF1A,KIF3A,LLGL1,LLGL2,MAP4K2,MYH10,RAB3A,SEPTIN5,SLC9A3R1,SNCA,SPIRE2,STXBP1,SUN1,TRAK2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9,TRIM58 |
| GO_REGULATION_OF_MAPK_CASCADE | 1.0e-07 | 1.8e-06 | 1125 | 769 | 43 | ADIPOQ,ADORA1,ADRB2,ARRB1,ARRB2,CDON,CHRNA9,DUSP22,EPHA7,ERBB4,FN1,FOXO1,FZD4,GAS6,GDF11,HYAL2,ID1,ITGB1BP1,JCAD,KDR,LPAR1,MAGI3,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,NPTN,PRKCA,PTK2B,ROCK2,SH3RF3,SHC2,SIRT3,SLC9A3R1,SORL1,SPRY3,STK38,SYNJ2BP,TAOK2,TIAM1,TNFRSF11A,TPD52L1 |
| GO_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 1.0e-07 | 1.8e-06 | 1125 | 152 | 17 | DNM3,EFNB2,EPHA7,ID1,LPAR1,MCF2,PRAG1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SPOCK1,TRAK2,YWHAH,ZNF365 |
| GO_RESPONSE_TO_INSULIN | 1.0e-07 | 1.8e-06 | 1125 | 271 | 23 | ADIPOQ,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CITED1,ENPP1,FOXO1,GPLD1,IRS1,LPL,NR1H4,PDE3B,PPARA,SCAP,SESN3,SORL1,SORT1,SREBF1,STAT1,STXBP4,VGF |
| GO_RHYTHMIC_PROCESS | 1.0e-07 | 1.8e-06 | 1125 | 293 | 24 | ADCY1,ADIPOQ,ADORA1,ARRB1,ARRB2,CRTC1,DBP,ESR1,FZD4,GPR157,HLF,ID1,KLF9,LGR4,NAGLU,PPARA,ROBO2,ROCK2,SREBF1,THRAP3,TNFRSF11A,TWIST1,USP2,ZP3 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 1.0e-07 | 1.8e-06 | 1125 | 432 | 30 | ARHGAP28,ATF7IP,BBS10,CAPZA2,CDC42EP3,CDH17,CPTP,CTNNBIP1,ERCC2,ERCC4,ESR1,EVL,GBA2,GFAP,IQGAP2,MPP7,NIN,PICK1,PTK2B,RAB3A,SMAD6,SNCA,SORL1,SOST,SPIDR,SPIRE2,STXBP1,TMOD2,UNC13B,VPS18 |
| GO_NEGATIVE_REGULATION_OF_TRANSPORT | 1.0e-07 | 2.1e-06 | 1125 | 534 | 34 | ADIPOQ,ADORA1,ANK3,APPL1,ATP7A,BCR,CD200,CPTP,DLG4,ENPP1,FGF12,FN1,GAS6,GJA1,GNB5,GOPC,IDH2,IRS1,ITGB1BP1,LGR4,MAOB,NR1H4,PKIA,PTK2B,RAB11FIP1,RGCC,SERGEF,SLC9A3R1,SNCA,SREBF1,TMEM14A,TWIST1,UCN,WWP2 |
| GO_EPITHELIAL_CELL_DIFFERENTIATION | 1.0e-07 | 2.1e-06 | 1125 | 774 | 43 | ADIPOQ,AGR2,ARHGEF26,BASP1,BCL11B,BCR,CCM2,CITED1,COL4A1,DNASE1L2,ERBB4,ERCC2,ESR1,FAM20C,FAT1,FAT4,FZD1,GSTK1,HEG1,HIF1A,ID1,JAG2,JUP,KDR,KRT80,LAMA1,LAMA5,LHFPL5,MEN1,PDZD7,PECAM1,PKP2,PRKCH,PRKX,PTCH1,ROCK2,SERPINB13,SLC9A3R1,SOX18,SPINT2,STAT1,TST,WNT11 |
| GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1.0e-07 | 2.1e-06 | 1125 | 459 | 31 | ANK3,APBB1,ARRB1,B3GAT3,C1QTNF4,GAS6,GJA1,GLI3,GPLD1,HIF1A,HYAL2,ITGB1BP1,JUP,LPL,MTCL1,MYH10,NLRP1,NLRP2,NR1H4,PARD6A,PFKFB2,PRKACA,RGCC,SIRT3,SORL1,TCAF1,TM7SF3,TRIM6,TWIST1,UNC13B,YWHAH |
| GO_REGULATION_OF_MEMBRANE_POTENTIAL | 1.0e-07 | 2.1e-06 | 1125 | 435 | 30 | ADORA1,ADRB1,ADRB2,ANK3,ARRB2,BCO2,BVES,CHRNA9,CHRNE,CRTC1,CXADR,DLG4,FGF12,GJA1,GJC1,GLRB,GPD1L,JUP,KDR,MPP2,P2RX1,PKP2,PTK2B,RNF207,RTL10,SCN1B,SNCA,UNC13B,WWP2,YWHAH |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 1.0e-07 | 2.2e-06 | 1125 | 561 | 35 | ADCY1,ANK3,APBB1,ATP5F1D,ATP7A,ATP7B,CASP9,CCS,CD9,CYB5A,CYP2R1,DLG4,FOXO1,FSTL3,GPHN,GPLD1,HIF1A,KDR,LIG4,LRP11,MAOB,MAP3K5,NSMCE3,PTCH1,PTK2B,RASA4,SLC25A12,SLC25A23,SLC30A4,SNCA,SPIDR,STAT1,TFAP2A,UROS,ZNF658 |
| GO_CELLULAR_RESPONSE_TO_PEPTIDE | 1.0e-07 | 2.2e-06 | 1125 | 388 | 28 | ADCY1,ADCY9,ADIPOQ,ADRB2,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ENPP1,FOXO1,GJA1,GNRHR2,GPLD1,ID1,IRS1,LPL,MEN1,NR1H4,PDE3B,PPP1R9B,PRKACA,ROCK2,SESN3,SORL1,SREBF1,STAT1,STXBP4 |
| GO_RESPONSE_TO_PEPTIDE_HORMONE | 1.0e-07 | 2.2e-06 | 1125 | 436 | 30 | ADCY1,ADCY9,ADIPOQ,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CITED1,ENPP1,FOXO1,GJA1,GNRHR2,GPLD1,IRS1,LPL,MEN1,NR1H4,PDE3B,PPARA,PRKACA,ROCK2,SCAP,SESN3,SORL1,SORT1,SREBF1,STAT1,STXBP4,VGF |
| GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS | 1.0e-07 | 2.4e-06 | 1125 | 320 | 25 | ACP6,ALDH5A1,BPNT1,CDS1,CHKA,EFR3A,ETNK2,GDE1,GPD1L,GPLD1,INPP4A,LPCAT3,LPCAT4,NR1H4,PCTP,PIGM,PIGN,PIGX,PLA2G12A,PLAAT3,PTPN13,RAB4A,SCARB1,SLC44A1,ZP3 |
| GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION | 1.0e-07 | 2.5e-06 | 1125 | 194 | 19 | ARHGAP28,ARRB1,ASAP3,CDC42BPG,CSRP1,EPB41L4B,EVL,FHDC1,FRMD5,ITGB1BP1,LIMK1,LPAR1,MYH10,PPM1E,PTK2B,RGCC,ROCK2,TMOD2,WNT11 |
| GO_MICROTUBULE_BASED_PROCESS | 1.0e-07 | 2.5e-06 | 1125 | 752 | 42 | ARL3,ARMC2,BBS2,CCDC68,CDC14B,CELSR2,CEP68,CFAP221,CFAP44,COPG2,CROCC,DISC1,DIXDC1,FYCO1,GAS2L1,GBA2,GJA1,HIF1A,IFT81,KATNAL2,KIF3A,KIF6,LLGL1,LLGL2,LMNA,MAP10,MAPRE2,MTCL1,NIN,PARD6A,PEX1,ROCK2,SNCA,SPG7,SPIRE2,STMN3,SUN1,TRAK2,TRIM58,TTLL1,TUBG2,WDR78 |
| GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 1.0e-07 | 2.5e-06 | 1125 | 439 | 30 | ARRB1,ARRB2,BASP1,CITED1,ESR1,ETNK2,FBXW8,FSTL3,FZD4,GJA1,GJB5,GLI2,GLI3,HIF1A,HTRA1,IMMP2L,LFNG,LGR4,MAMLD1,MEN1,PLCD3,PLEKHA5,PPP1R9B,PTCH1,ROBO2,SPINT2,STK11,SULF1,VGF,ZP3 |
| GO_RECEPTOR_METABOLIC_PROCESS | 1.0e-07 | 2.7e-06 | 1125 | 195 | 19 | ADIPOQ,AP2A2,ARRB1,ARRB2,BVES,CD9,DLG4,DNM3,EFNB2,HIF1A,LDLRAP1,PHETA1,PICK1,PPARA,SCAP,SNCA,SNX1,SORL1,TBC1D16 |
| GO_RESPONSE_TO_ACID_CHEMICAL | 1.0e-07 | 2.6e-06 | 1125 | 345 | 26 | ADIPOQ,ATP7A,BCHE,CD9,COL4A1,DGAT2,FOXO1,FZD4,GJA1,GLRB,HLCS,IGFBP7,IRS1,KDR,LPL,LRP11,MTHFR,NR1H4,PPP1R9B,PTCH1,PTK2B,RRAGA,SESN3,SH3BP4,SREBF1,WNT11 |
| GO_DEVELOPMENTAL_MATURATION | 1.0e-07 | 3.0e-06 | 1125 | 280 | 23 | AGRN,ANKS1A,C1QL1,CLN5,DISC1,DLG4,ERCC2,FAM20C,FAT4,GDF11,HIF1A,MAP3K13,PICK1,PRKACA,PTK2B,RAB3A,RECK,RFLNB,SNX19,SOX18,STXBP1,TRIM58,UNC13B |
| GO_RESPONSE_TO_COLD | 1.0e-07 | 2.9e-06 | 1125 | 49 | 10 | ADRB1,ADRB2,CDH8,FOXO1,GMPR,HSPA2,LPL,LRP11,MT-CO2,VGF |
| GO_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 1.0e-07 | 3.2e-06 | 1125 | 444 | 30 | ADCY1,ADIPOQ,ADORA1,ADRB2,ARRB2,BCHE,BCR,CRTC1,DISC1,DLG4,MPP2,NPTN,P2RX1,PCDH17,PICK1,PPFIA3,PPP1R9B,PRKACA,PTK2B,RAB26,RAB3A,SEPTIN5,SNAP47,SNCA,SORCS2,STXBP1,UCN,UNC13B,VPS18,YWHAH |
| GO_PATTERN_SPECIFICATION_PROCESS | 1.0e-07 | 3.4e-06 | 1125 | 446 | 30 | BASP1,CDON,CELSR2,CITED1,CTNNBIP1,CXXC4,ERBB4,GALNT11,GDF11,GLI2,GLI3,GRHL3,HIF1A,HOXD8,IRX2,LFNG,LRP5,PBX1,POGLUT1,PRKACA,PTCH1,RNF207,ROBO2,SEMA3F,SKI,SMAD6,SMARCD3,SOX18,SSBP3,TGFBR2 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 1.0e-07 | 3.3e-06 | 1125 | 326 | 25 | ABHD17A,AGR2,ANK3,B3GAT3,CARD10,CROCC,ERBB4,GAS6,GLI3,GPD1L,HYAL2,ITGA3,ITGB1BP1,JUP,MTCL1,NPTN,PARD6A,PPP1R9B,PRKACA,PRKCH,ROCK2,SORL1,STK11,TCAF1,YWHAH |
| GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 1.0e-07 | 3.4e-06 | 1125 | 573 | 35 | ADIPOQ,ADRB2,ANK3,APPL1,ARPP19,ATP7A,ATPSCKMT,CLCN2,DLG3,DLG4,ENPP1,FGF12,GJA1,GNB5,GOPC,GPD1L,HSPA2,IRS1,KCNJ1,LRRC7,MINK1,PRKACA,PTK2B,RNF207,SCN1B,SLC9A3R1,SNCA,STIM2,STXBP4,TCAF1,TMEM37,TPCN1,TWIST1,WWP2,YWHAH |
| GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 1.0e-07 | 3.4e-06 | 1125 | 547 | 34 | ADCY1,ADIPOQ,APPL1,ARRB1,ARRB2,BCR,BVES,DLG4,DNAJC6,DNM3,EFNB2,GAS6,GOPC,HIP1,LDLRAP1,P2RX1,PCDH17,PICK1,RAB26,RAB3A,RAB3D,RAB4A,RAPGEF4,SCARB1,SEPTIN1,SEPTIN5,SNCA,SORL1,STXBP1,SYNJ2BP,TNK2,UNC13B,VPS18,ZP3 |
| GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | 2.0e-07 | 3.5e-06 | 1125 | 219 | 20 | CYTH3,DLG3,FAT1,GJA1,LAMA1,LLGL1,LLGL2,LMNA,LRRC7,MPP7,MTCL1,PARD6A,PTK2B,RHOBTB1,ROCK2,SLC9A3R1,SPINT2,STK11,SYNJ2BP,WNT11 |
| GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 2.0e-07 | 3.6e-06 | 1125 | 199 | 19 | CITED1,COL4A1,CTNNBIP1,EPHA7,ESR1,FAT4,GLI2,GLI3,LAMA1,LAMA5,LGR4,LRP5,MAP3K13,PBX1,PLXND1,PTCH1,SPINT2,SULF1,TGFBR2 |
| GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 2.0e-07 | 3.5e-06 | 1125 | 261 | 22 | ACP6,CDS1,CHKA,ETNK2,FITM2,GPD1L,INPP4A,LPCAT3,LPCAT4,NR1H4,PCTP,PIGM,PIGN,PIGX,PLA2G12A,PLAAT3,PMVK,PTPN13,RAB4A,SGMS1,SLC44A1,ZP3 |
| GO_REGULATION_OF_AUTOPHAGY | 2.0e-07 | 3.6e-06 | 1125 | 328 | 25 | ADRB2,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CPTP,ERCC4,FOXO1,FYCO1,GFAP,GPSM1,HERC1,HIF1A,KDR,MTCL1,PRKACA,RRAGA,SCOC,SESN3,SH3BP4,SNCA,SREBF1,STK11,TPCN1,ZKSCAN3 |
| GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 2.0e-07 | 3.9e-06 | 1125 | 376 | 27 | ADAM10,ADCY9,ATP7A,CCM2,CITED1,ERCC2,ETNK2,FBXW8,GJB5,GLI2,GLI3,HEG1,HIF1A,JAG2,LIG4,MYH10,PLCD3,PTCH1,SOX18,SPINT2,STMN3,TANC2,TENT5C,TGFBR2,TWIST1,ZFP14,ZP3 |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 2.0e-07 | 3.9e-06 | 1125 | 499 | 32 | ADRB2,ATG10,ATG2A,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CPTP,ERCC4,FOXO1,FYCO1,GFAP,GPSM1,HERC1,HIF1A,KDR,MTCL1,PACS2,PRKACA,RGS19,RRAGA,SCOC,SESN3,SH3BP4,SNCA,SREBF1,STK11,STX17,TECPR2,TPCN1,VPS18,ZKSCAN3 |
| GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 2.0e-07 | 3.9e-06 | 1125 | 577 | 35 | ADCY1,ADCY9,ADIPOQ,ADORA1,ADRB2,ARRB1,CARD10,CCNYL1,DLG3,DLG4,FZD4,GAS6,IL18,IRS1,ITGB1BP1,LPAR1,MAP3K13,MAP3K5,MAP4K2,MINK1,PFKFB2,PRKACA,PTK2B,RGCC,SHC2,SNCA,STK11,TAOK2,TGFBR2,TIAM1,TNFRSF11A,TPD52L1,UCN,VAV3,WNT11 |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 2.0e-07 | 4.0e-06 | 1125 | 604 | 36 | ADAM10,ATP7A,BVES,CAVIN1,EPB41L4B,FN1,FOXP1,GAS6,GPLD1,HIF1A,IQSEC1,ITGA3,ITGB1BP1,JCAD,KDR,LPAR1,MAPRE2,MCAM,MIEN1,PECAM1,PRKCA,PTK2B,ROCK2,SCARB1,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TGFBR2,TIAM1,TNFSF14,TWIST1,VSIR,WNT11,ZP3 |
| GO_STEROID_METABOLIC_PROCESS | 2.0e-07 | 4.2e-06 | 1125 | 331 | 25 | AMACR,ATP8B1,CLCN2,CYP2R1,CYP4V2,DGAT2,ELOVL6,ERLIN2,ESR1,GBA2,HINT2,HSD17B8,IGFBP7,LDLRAP1,LIPE,NR1H4,PBX1,PLPP6,PMVK,SCAP,SCARB1,SREBF1,SULT1A4,TM7SF2,YWHAH |
| GO_NEPHRON_EPITHELIUM_DEVELOPMENT | 2.0e-07 | 4.5e-06 | 1125 | 110 | 14 | ADIPOQ,BASP1,CITED1,CTNNBIP1,FAT4,GLI3,IRX2,LAMA5,LGR4,PBX1,PECAM1,PTCH1,STAT1,WNT11 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 2.0e-07 | 4.4e-06 | 1125 | 912 | 47 | ADRB2,ANKIB1,ARRB1,ARRB2,ASB16,ATG10,CDC14B,ENC1,FBH1,FBXL16,FBXL4,FBXO21,FBXO33,FBXW8,H2BC4,HECTD3,HERC1,HIF1A,HMG20B,KLHL13,KLHL7,KLHL9,LIMK1,MAGEF1,MARCHF2,MARCHF9,MOCS3,NSMCE3,NUP210,PEX2,PRICKLE1,RAG1,RASSF5,RMND5B,RNF123,RNF141,RNF212,RNFT1,RRAGA,SH3RF3,TRIM44,TRIM58,TRIM6,UBE2D4,UBE2L6,WWP2,ZMIZ2 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | 2.0e-07 | 4.5e-06 | 1125 | 110 | 14 | AP2A2,ARHGEF19,ARRB2,CELSR2,FZD1,FZD3,FZD4,GRHL3,PARD6A,PRICKLE1,PRICKLE2,TIAM1,VANGL1,WNT11 |
| GO_KIDNEY_MORPHOGENESIS | 2.0e-07 | 4.5e-06 | 1125 | 94 | 13 | BASP1,CITED1,CTNNBIP1,FAT4,GLI3,IRX2,LAMA5,LGR4,PBX1,PRKX,PTCH1,STAT1,WNT11 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 2.0e-07 | 4.8e-06 | 1125 | 974 | 49 | ADAM10,ARMC2,ARRB1,ARRB2,BASP1,BBS2,C11orf74,CFAP44,CITED1,ESR1,ETNK2,FBXW8,FSTL3,FZD4,GJA1,GJB5,GLI2,GLI3,HIF1A,HSPA2,HTRA1,IFT81,IMMP2L,JAG2,LFNG,LGR4,MAMLD1,MARF1,MEIG1,MEN1,PAQR8,PBX1,PLCD3,PPP1R9B,PRKACA,PTCH1,PTK2B,ROBO2,SPINT2,STK11,STXBP1,SULF1,SUN1,TCFL5,TTLL1,TXNRD3,VGF,ZFP41,ZP3 |
| GO_NEGATIVE_REGULATION_OF_CELL_GROWTH | 2.0e-07 | 5.1e-06 | 1125 | 184 | 18 | APBB1,CCDC85B,DCBLD2,ENPP1,EPHA7,GJA1,HYAL2,PPARA,PPP1R9B,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SH3BP4,STK11,WNT11 |
| GO_POSITIVE_REGULATION_OF_SECRETION | 2.0e-07 | 5.2e-06 | 1125 | 431 | 29 | ADORA1,APBB1,ARRB1,C1QTNF4,GJA1,GPLD1,HIF1A,HYAL2,LPL,MYH10,NLRP1,NLRP2,NR1H4,PARD6A,PFKFB2,RAB3A,RAB3D,RGCC,SIRT3,SNCA,SORL1,STXBP1,TM7SF3,TNFRSF11A,TRIM6,TWIST1,UCN,UNC13B,ZP3 |
| GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 2.0e-07 | 5.8e-06 | 1125 | 96 | 13 | DNM3,EPHA7,ID1,ITGB1BP1,MCF2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TRAK2,YWHAH |
| GO_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 2.0e-07 | 5.7e-06 | 1125 | 433 | 29 | ADCY1,ARRB1,ARRB2,BEX1,CD200,CRTC1,CTNNBIP1,ENPP1,ESR1,FZD1,FZD4,GAS6,ID1,IL18,JUP,MAP3K13,MEN1,NLRP2,NR1H4,PRKCH,PTCH1,RAB7B,RGCC,SGK1,TNFRSF11A,TRAPPC9,TRIM34,TWIST1,WWP2 |
| GO_NEURAL_CREST_CELL_MIGRATION | 3.0e-07 | 5.8e-06 | 1125 | 53 | 10 | ERBB4,FN1,HIF1A,LAMA5,NRTN,SEMA3F,SEMA4F,SEMA4G,SEMA6D,TWIST1 |
| GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | 3.0e-07 | 5.9e-06 | 1125 | 292 | 23 | ADORA1,APBB1,ARRB1,C1QTNF4,GJA1,GPLD1,HIF1A,HYAL2,LPL,MYH10,NLRP1,NLRP2,NR1H4,PARD6A,PFKFB2,RGCC,SIRT3,SORL1,TM7SF3,TRIM6,TWIST1,UCN,UNC13B |
| GO_GLAND_DEVELOPMENT | 3.0e-07 | 6.8e-06 | 1125 | 437 | 29 | ATP7A,ATP7B,BCL11B,CLCN2,CTC1,DBP,ERBB4,ESR1,FSTL3,GLI2,GLI3,HIF1A,JARID2,LAMA1,LAMA5,LRP5,MT-CO2,PBX1,PLXND1,PTCD2,PTCH1,RAG1,SLC9A3R1,STK11,SULF1,TG,TGFBR2,TNFRSF11A,WNT11 |
| GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 3.0e-07 | 7.3e-06 | 1125 | 98 | 13 | ARHGAP28,ARRB1,ASAP3,EVL,FHDC1,ITGB1BP1,LIMK1,LPAR1,PPM1E,PTK2B,RGCC,ROCK2,WNT11 |
| GO_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS | 4.0e-07 | 8.0e-06 | 1125 | 320 | 24 | ADCY1,ADCY9,ADIPOQ,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ENPP1,FOXO1,GNRHR2,GPLD1,IRS1,LPL,MEN1,NR1H4,PDE3B,PRKACA,ROCK2,SESN3,SORL1,SREBF1,STAT1,STXBP4 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE | 4.0e-07 | 8.0e-06 | 1125 | 367 | 26 | ARHGAP28,ATP7A,CAPZA2,CDC42EP3,DISC1,EPHA7,EVL,FN1,GBA2,IQGAP2,LIMK1,MAP3K13,PICK1,PTK2B,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC12A5,SLC9A3R1,SPIRE2,TMOD2,UCN,VAV3 |
| GO_ENDOTHELIAL_CELL_MIGRATION | 4.0e-07 | 8.1e-06 | 1125 | 275 | 22 | CARD10,EFNB2,FOXP1,GPLD1,HIF1A,ID1,ITGB1BP1,JCAD,JUP,KDR,PECAM1,PLXND1,PRKCA,PRKX,PTK2B,PTPRM,RGCC,ROCK2,SCARB1,SEMA5A,SOX18,SYNJ2BP |
| GO_EPITHELIAL_CELL_PROLIFERATION | 4.0e-07 | 8.1e-06 | 1125 | 441 | 29 | ATP7A,BCL11B,C6orf89,EFNB2,ESR1,GJA1,HIF1A,HTRA1,ID1,ITGB1BP1,JCAD,KDR,KLF9,LGR4,MEN1,PEX2,PRKCA,PRKX,PTCH1,PTPRM,RGCC,SCARB1,SEMA5A,STAT1,STK11,STXBP4,SULF1,SYNJ2BP,TWIST1 |
| GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS | 4.0e-07 | 8.2e-06 | 1125 | 55 | 10 | ABCD2,ADORA1,GPLD1,IRS1,MLYCD,PDE3B,PPARA,SCARB1,SORL1,TWIST1 |
| GO_BEHAVIOR | 4.0e-07 | 8.5e-06 | 1125 | 598 | 35 | ADCY1,ADORA1,ARRB2,ATP7A,BBS2,BCHE,C1QL1,CRTC1,DLG4,FGF12,FZD4,GJA1,GLRB,GM2A,GPR157,HIF1A,HTR1D,ITGA3,MRAP2,NAGLU,NOVA1,NPTN,PCDH17,PPARA,PPP1R9B,RAG1,SEPTIN5,SGK1,SLC12A5,SNCA,TANC1,TMOD2,UCN,USP2,ZDHHC8 |
| GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS | 4.0e-07 | 8.5e-06 | 1125 | 191 | 18 | ALDH4A1,ALDH5A1,ALDH7A1,CKMT1A,CKMT1B,CRAT,CROT,DHFR2,GSTA4,GSTK1,LPCAT3,LPCAT4,MTHFR,PCYOX1L,PLA2G12A,PLAAT3,SLC46A1,TG |
| GO_MUSCLE_SYSTEM_PROCESS | 4.0e-07 | 9.5e-06 | 1125 | 470 | 30 | ADORA1,ADRB2,BBS2,BDKRB2,CHRM3,CHRNE,FGF12,FOXO1,GJA1,GJC1,GPD1L,HSPB6,HTR1D,JARID2,JUP,LMNA,LTB4R,P2RX1,PKP2,PPARA,PRKACA,PRKCA,RNF207,ROCK2,SCN1B,SULF1,TIAM1,TMOD2,UCN,VCL |
| GO_MYELOID_CELL_DIFFERENTIATION | 4.0e-07 | 9.6e-06 | 1125 | 420 | 28 | ADIPOQ,AGO1,ASH2L,CASP9,CTNNBIP1,EIF2AK1,ERCC2,FAM20C,FOXP1,FSTL3,H3C10,H3C12,H4C9,HIF1A,IRF4,LILRB3,NBEAL2,PRKCA,PRKX,PTK2B,PURB,RAB7B,SNX10,STAT1,TGFBR2,TNFRSF11A,TNRC6C,TRIM58 |
| GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | 4.0e-07 | 9.7e-06 | 1125 | 173 | 17 | ADORA1,ADRB1,ADRB2,BBS2,BCR,BDKRB2,CHRM3,CTNNBIP1,DDAH1,FGFBP3,GJA1,HTR1D,ITGB1BP1,P2RX1,PTPRM,ROCK2,UCN |
| GO_CELL_CYCLE_PROCESS | 5.0e-07 | 1.0e-05 | 1125 | 1399 | 62 | ANK3,APBB1,ARL3,ARPP19,CBX5,CCNJL,CDC14B,CEP68,CHMP7,CRADD,CROCC,CTC1,DIS3L2,ERCC2,ERCC4,FOXN3,GAS2L1,GAS6,GJA1,HSPA2,IK,KIF3A,KLHL13,KLHL9,KLLN,LLGL1,LLGL2,LMNA,LRP5,MAP10,MAPRE2,MARF1,MEN1,MYH10,NEK9,NIN,NSL1,NUDT16,NUPR2,PARD6A,PBX1,PKIA,PPP1R9B,PRKACA,PRKCA,RGCC,RNF212,ROCK2,RRAGA,SEPTIN1,SEPTIN5,SLX4,SMARCD3,SPIRE2,STK11,STXBP4,SUN1,TAOK2,TPD52L1,TTC19,TUBG2,UHMK1 |
| GO_MESONEPHROS_DEVELOPMENT | 5.0e-07 | 1.0e-05 | 1125 | 101 | 13 | BASP1,CITED1,CTNNBIP1,FAT4,GDF11,GLI3,LAMA5,LGR4,PBX1,PTCH1,ROBO2,SMAD6,WNT11 |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 5.0e-07 | 1.1e-05 | 1125 | 856 | 44 | ACTR5,APBB1,ASH2L,BRAT1,CASP9,CBX5,CDC14B,CRADD,CTC1,ERCC2,ERCC4,EYA4,FAAP100,FAN1,FBH1,FOXN3,FOXO1,FOXP1,H2AW,H4C9,IMMP2L,LIG4,MAGEF1,MARF1,MEN1,NSMCE3,NUDT16,NUPR2,RADX,RGCC,SGK1,SLX4,SPIDR,SPIRE2,STK11,STXBP4,SWSAP1,TAOK2,TWIST1,UBE2L6,VAV3,ZBTB42,ZMAT3,ZNF365 |
| GO_ENDOCYTOSIS | 5.0e-07 | 1.2e-05 | 1125 | 661 | 37 | ACTBL2,ADRB2,AP2A2,APPL1,ARRB1,ARRB2,CD9,CFI,DLG4,DNAJC6,DNM3,EFNB2,ENPP1,HIP1,IGHV4-34,LDLRAD3,LDLRAP1,LGALS3BP,LRP3,LRP5,LY75,MARCHF2,PICK1,PRSS12,RAB4A,RINL,SCARB1,SCART1,SH3BP4,SNCA,SNX1,SNX10,SORL1,SORT1,SYNJ2BP,TGFBR2,TNK2 |
| GO_CELL_ACTIVATION | 6.0e-07 | 1.3e-05 | 1125 | 1442 | 63 | ACPP,ADAM10,AP2A2,ARRB1,ARRB2,ATP6V0A1,ATP7A,BCL11B,BCR,C1GALT1C1,CD200,CD9,CDH17,COMMD3,CSRP1,CXADR,DUSP22,EFNB2,F2RL2,F8,FOXP1,GAS6,GHDC,GLI2,GLI3,GM2A,HYAL2,IGHV4-34,IL18,IQGAP2,IRF4,ITM2A,JAG2,JUP,KLRC4-KLRK1,LFNG,LIG4,LILRB3,LRRC7,MVP,NBEAL2,P2RX1,PECAM1,PRKCA,PRKCH,PTK2B,PYGB,RAB3A,RAB3D,RAG1,RGCC,SATB1,SNCA,SOX13,STK11,STXBP1,TGFBR2,TNFSF14,TRAPPC1,VAV3,VCL,VSIR,ZP3 |
| GO_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS | 6.0e-07 | 1.4e-05 | 1125 | 139 | 15 | ACSM2B,BPNT1,CROT,DGAT2,ELOVL6,ENPP1,FAR2,HSD17B8,MLYCD,MPC1,NUDT7,PAPSS1,PMVK,SNCA,SULT1A4 |
| GO_RENAL_SYSTEM_PROCESS | 6.0e-07 | 1.4e-05 | 1125 | 121 | 14 | ADCY1,ADCY9,ADIPOQ,ADORA1,BCR,GAS6,GJA1,HYAL2,ITGA3,MCAM,PRKACA,SGK1,SLC9A3R1,SULF1 |
| GO_IMPORT_INTO_CELL | 7.0e-07 | 1.5e-05 | 1125 | 810 | 42 | ACTBL2,ADRB2,AP2A2,APPL1,ARRB1,ARRB2,CD9,CFI,DLG4,DNAJC6,DNM3,EFNB2,ENPP1,HIP1,IGHV4-34,KCNJ1,LDLRAD3,LDLRAP1,LGALS3BP,LRP3,LRP5,LY75,MARCHF2,PICK1,PRSS12,RAB4A,RINL,SCARB1,SCART1,SH3BP4,SLC12A5,SLC46A1,SLC9A6,SLC9A7,SNCA,SNX1,SNX10,SORL1,SORT1,SYNJ2BP,TGFBR2,TNK2 |
| GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 8.0e-07 | 1.6e-05 | 1125 | 141 | 15 | ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,BCR,CCDC125,F2RL2,HEG1,ITGA3,LPAR1,MCF2,PRAG1,RTN4R,TIAM1,VAV3 |
| GO_NEURAL_TUBE_DEVELOPMENT | 8.0e-07 | 1.8e-05 | 1125 | 161 | 16 | FZD1,FZD3,GLI2,GLI3,GRHL3,HIF1A,ITPK1,LUZP1,MTHFR,PRICKLE1,PRKACA,PTCH1,SKI,SPINT2,SSBP3,TWIST1 |
| GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 9.0e-07 | 1.8e-05 | 1125 | 124 | 14 | CITED1,CTNNBIP1,FAM20C,GLI3,ID1,LRP5,MEN1,PRKACA,PTCH1,SKI,SMAD6,SMOC1,TWIST1,ZHX3 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 9.0e-07 | 1.8e-05 | 1125 | 1114 | 52 | ACTR5,ADRB2,ANKIB1,ARRB1,ARRB2,ASB16,ATG10,CDC14B,ENC1,ESR1,FBH1,FBXL16,FBXL4,FBXO21,FBXO33,FBXW8,H2BC4,HECTD3,HERC1,HIF1A,HMG20B,KLHL13,KLHL7,KLHL9,LIMK1,MAGEF1,MARCHF2,MARCHF9,MOCS3,NSMCE3,NUP210,PEX2,PRICKLE1,RAG1,RASSF5,RMND5B,RNF123,RNF141,RNF212,RNFT1,RRAGA,SENP8,SH3RF3,TRIM44,TRIM58,TRIM6,UBE2D4,UBE2L6,USP2,USP48,WWP2,ZMIZ2 |
| GO_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 9.0e-07 | 1.9e-05 | 1125 | 435 | 28 | ABCD2,ADIPOQ,ARPP19,ATPSCKMT,CLCN2,DGAT2,ELOVL6,ENPP1,ERLIN2,FOXO1,GPLD1,HIF1A,IRS1,LDLRAP1,MLYCD,MT-CO2,NR1H4,NUP210,PFKFB2,PMVK,PPARA,PTK2B,SCAP,SLC25A12,SNCA,SREBF1,TM7SF2,TWIST1 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 9.0e-07 | 1.9e-05 | 1125 | 1146 | 53 | AASDH,ACSM2B,ADAM10,AGO1,ALDH5A1,ASAH2,B3GALT1,BTD,CLN5,DGAT2,DHFR2,EIF2AK1,ELOVL6,ENC1,ENPEP,FAR2,GBA2,GGA3,GM2A,GSPT2,GSTA4,GSTK1,HABP4,HLCS,HSD17B8,IMMP2L,MLYCD,MPC1,MRPL33,MRPS28,MTFMT,MTHFR,MTIF3,NR1H4,NUDT7,P2RX1,PAIP2B,PARS2,PCSK1,PLAAT3,PMVK,PTK2B,ROCK2,SGMS1,SIRT3,SLC46A1,SNCA,SORL1,ST6GALNAC3,TNRC6C,UCN,UHMK1,ZNF540 |
| GO_REGULATION_OF_PROTEIN_BINDING | 9.0e-07 | 2.0e-05 | 1125 | 224 | 19 | ADIPOQ,ADRB2,ARRB1,ARRB2,CDON,CTNNBIP1,DISC1,GPSM1,ID1,ITGB1BP1,LDLRAP1,LFNG,MEN1,PLXND1,PPARA,PRKACA,SMARCD3,SORL1,TIAM1 |
| GO_HORMONE_TRANSPORT | 1.0e-06 | 2.1e-05 | 1125 | 315 | 23 | ADIPOQ,ADORA1,ARRB1,EXOC3L1,FZD4,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,PFKFB2,PRKCA,RAB11FIP1,RAPGEF4,SIRT3,SNX19,SREBF1,STXBP4,TIAM1,TM7SF3,UCN,VGF |
| GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 1.0e-06 | 2.1e-05 | 1125 | 463 | 29 | ARPP19,ARRB1,ARRB2,COL28A1,CSRNP3,DLG3,ELFN2,GAS6,GPSM1,IQGAP2,KLRC4-KLRK1,MARF1,PHACTR2,PPP1R9B,RAG1,RASA4,RECK,ROCK2,SERPINB13,SERPING1,SERPINI1,SH3BP4,SNCA,SORL1,SORT1,SPINT2,SPOCK1,TNFSF14,TNK2 |
| GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 1.0e-06 | 2.1e-05 | 1125 | 292 | 22 | CARD10,EPB41L4B,EVL,FOXP1,GPLD1,HIF1A,IQSEC1,ITGA3,ITGB1BP1,JCAD,JUP,KDR,MAPRE2,PRKCA,PTK2B,PTPRM,RGCC,ROCK2,SCARB1,SEMA5A,SYNJ2BP,TGFBR2 |
| GO_REGULATION_OF_PROTEOLYSIS | 1.0e-06 | 2.1e-05 | 1125 | 735 | 39 | ANKIB1,ANTXR1,ARRB1,ARRB2,CASP9,COL28A1,CRADD,DISC1,EPHA7,F8A1,F8A3,FBXW8,FN1,GAS6,GPLD1,HIP1,LDLRAD3,MAGEF1,MAP3K5,NLRP1,NLRP2,P2RX1,PRICKLE1,PRKACA,PTK2B,RAG1,RECK,RNFT1,ROCK2,SERPINB13,SERPING1,SERPINI1,SNCA,SORL1,SPINT2,SPOCK1,TMTC3,TNFSF14,VSIR |
| GO_ANION_TRANSMEMBRANE_TRANSPORT | 1.1e-06 | 2.3e-05 | 1125 | 294 | 22 | ABCD3,CLCN2,GJA1,GLRB,GOPC,LRRC8B,MPC1,PRAF2,SLC12A5,SLC16A12,SLC25A12,SLC25A18,SLC25A29,SLC25A42,SLC35A1,SLC36A1,SLC46A1,SLC4A4,SLC9A6,SLC9A7,TCAF1,TTYH3 |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 1.1e-06 | 2.2e-05 | 1125 | 737 | 39 | ADAM10,ADIPOQ,ADORA1,APBB1,ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,ARRB2,CASP9,CRADD,CSRNP3,EFNB2,EPHA7,FBH1,FOXO1,GPLD1,HIP1,HYAL2,LPAR1,MAP3K5,MCF2,MT-CO2,NLRP1,NLRP2,P2RX1,RGCC,RPS6KA2,SLC9A3R1,SNCA,SORT1,TFAP2A,TIAM1,TPD52L1,UNC13B,VAV3,WNT11,YWHAH,ZMAT3 |
| GO_RESPONSE_TO_METAL_ION | 1.1e-06 | 2.2e-05 | 1125 | 364 | 25 | ADCY1,ANK3,APBB1,ATP5F1D,ATP7A,ATP7B,CASP9,CYB5A,CYP2R1,DLG4,FSTL3,GPHN,GPLD1,HIF1A,LIG4,MAOB,PTK2B,RASA4,SLC25A12,SLC25A23,SLC30A4,SNCA,TFAP2A,UROS,ZNF658 |
| GO_LIPID_LOCALIZATION | 1.2e-06 | 2.5e-05 | 1125 | 417 | 27 | ABCA3,ABCD3,ADIPOQ,ATP8B1,ATP8B3,BDKRB2,CHKA,CPTP,CROT,DGAT2,ENPP1,FITM2,FZD4,GM2A,LDLRAP1,LPL,NR1H4,PCTP,PITPNC1,PLA2G12A,PLA2G2C,PPARA,PTCH1,SCARB1,SLC51A,TEX2,TNFRSF11A |
| GO_MEMBRANE_LIPID_METABOLIC_PROCESS | 1.3e-06 | 2.6e-05 | 1125 | 207 | 18 | ALDH3A2,ALDH5A1,ASAH2,B3GALT1,CPTP,ELOVL6,GBA2,GM2A,GPLD1,P2RX1,PIGM,PIGN,PIGX,SGMS1,SIRT3,SPTLC3,ST6GALNAC3,TEX2 |
| GO_PLATELET_DEGRANULATION | 1.3e-06 | 2.6e-05 | 1125 | 128 | 14 | CD9,F8,FN1,GAS6,HABP4,LGALS3BP,P2RX1,PCDH7,PCYOX1L,PECAM1,PHACTR2,SERPING1,STXBP1,VCL |
| GO_PROTEIN_DEPHOSPHORYLATION | 1.3e-06 | 2.6e-05 | 1125 | 320 | 23 | ADORA1,ARPP19,B3GAT3,CDC14B,DNAJC6,DUSP22,ELFN2,EYA4,FAM220A,LHPP,MINPP1,PHACTR2,PPEF1,PPM1E,PPM1H,PPP1R9B,PPP2R5A,PTPN13,PTPN14,PTPRM,ROCK2,SSH2,STK11 |
| GO_PROTEIN_O_LINKED_GLYCOSYLATION_VIA_SERINE | 1.3e-06 | 2.6e-05 | 1125 | 10 | 5 | GALNT1,GALNT2,MGAT5B,POGLUT1,POGLUT3 |
| GO_RESPONSE_TO_CARBOHYDRATE | 1.3e-06 | 2.6e-05 | 1125 | 229 | 19 | ADIPOQ,ARRB1,GAS6,GJA1,GPLD1,HIF1A,LPL,LRP5,MEN1,NR1H4,PFKFB2,PRKACA,PTK2B,SARM1,SREBF1,STXBP4,TGFBR2,TIAM1,UNC13B |
| GO_MANNOSYLATION | 1.4e-06 | 2.8e-05 | 1125 | 37 | 8 | ALG1,ALG1L,B4GAT1,CRPPA,DPY19L1,DPY19L3,TMTC2,TMTC3 |
| GO_NEPHRON_MORPHOGENESIS | 1.4e-06 | 2.8e-05 | 1125 | 78 | 11 | CITED1,CTNNBIP1,FAT4,GLI3,IRX2,LAMA5,LGR4,PBX1,PTCH1,STAT1,WNT11 |
| GO_BONE_MINERALIZATION | 1.5e-06 | 3.0e-05 | 1125 | 112 | 13 | ADRB2,ENPP1,ERCC2,FAM20C,HIF1A,LGR4,MINPP1,PTK2B,RFLNB,SNX10,TFAP2A,TWIST1,WNT11 |
| GO_MESENCHYME_DEVELOPMENT | 1.5e-06 | 3.0e-05 | 1125 | 276 | 21 | BASP1,BCL9L,ERBB4,FN1,HIF1A,LAMA5,NRTN,POGLUT1,RFLNB,RGCC,ROBO2,S100A4,SEMA3F,SEMA4F,SEMA4G,SEMA6D,STAT1,TGFBR2,TIAM1,TWIST1,WNT11 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 1.5e-06 | 3.0e-05 | 1125 | 526 | 31 | AGRN,ATP7A,CDC42EP3,CDH17,CROCC,DNM3,ERCC2,ERCC4,ESR1,EVL,ID1,IQGAP2,ITGB1BP1,KDR,LIMK1,LPAR1,MIEN1,MPP7,NIN,PICK1,PPM1E,PRKCA,PTK2B,RGCC,ROCK2,SLX4,SPIDR,SPIRE2,THBS2,UNC13B,WNT11 |
| GO_POSTSYNAPSE_ORGANIZATION | 1.5e-06 | 2.9e-05 | 1125 | 168 | 16 | ABHD17A,ACTBL2,ADAM10,DLG3,DLG4,DNM3,EPHA7,GLRB,GPHN,ITGA3,MYH10,PICK1,SEMA3F,TANC1,TIAM1,ZNF365 |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 1.5e-06 | 3.0e-05 | 1125 | 526 | 31 | ADIPOQ,ADRB1,ADRB2,BBS2,BCHE,BCKDHB,C12orf66,EIF2AK1,FOXO1,GAS2L1,GAS6,HLCS,LPL,LRP11,MAP3K5,MTHFR,NR1H4,NUPR2,P2RX1,PICK1,PPARA,PPP1R9B,RRAGA,SESN3,SORL1,SREBF1,STAT1,TGFBR2,UCN,VGF,WNT11 |
| GO_SKELETAL_SYSTEM_DEVELOPMENT | 1.5e-06 | 3.0e-05 | 1125 | 526 | 31 | ACP2,ATP7A,BBS2,CTC1,FAM20C,FAT4,FGFRL1,FOXN3,FOXP1,GDF11,GJA1,GLI2,GLI3,GPLD1,HIF1A,HOXD8,HYAL2,JAG2,LRP5,PAPSS1,PBX1,PEX7,RFLNB,SKI,SNX19,SULF1,TFAP2A,TGFBR2,TRAPPC2,TWIST1,WNT11 |
| GO_REGULATION_OF_DEVELOPMENTAL_GROWTH | 1.6e-06 | 3.1e-05 | 1125 | 348 | 24 | ADRB1,ADRB2,AGR2,AGRN,BASP1,BBS2,DISC1,EPHA7,ERBB4,FN1,GJA1,JARID2,LIMK1,MAP3K13,PPARA,PTCH1,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TGFBR2,ZP3 |
| GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 1.7e-06 | 3.3e-05 | 1125 | 233 | 19 | DISC1,EPHA7,ESR1,FN1,LIMK1,MAP3K13,NIN,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A6,STK11,TGFBR2,TIAM1,VCL,WNT11 |
| GO_PROTEIN_AUTOPHOSPHORYLATION | 1.7e-06 | 3.3e-05 | 1125 | 233 | 19 | ADIPOQ,BCR,EIF2AK1,ENPP1,EPHA7,ERBB4,KDR,MAP3K13,MINK1,MVP,PPP2R5A,PRKACA,PRKX,PTK2B,SLA,STK11,TAOK2,TNK2,UHMK1 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 1.7e-06 | 3.3e-05 | 1125 | 751 | 39 | AGR2,APBB1,BDKRB2,CASP9,DDAH1,DUSP22,EIF2AK1,ERCC4,EYA4,FBH1,FOXO1,FZD1,FZD4,HIF1A,MAGEF1,MAGI3,MAP3K13,MAP3K5,MAP4K2,MEN1,MINK1,NUDT16,NUP210,PTK2B,RADX,RNFT1,ROCK2,RTN4R,SH3RF3,SLC25A23,SPIDR,SPIRE2,TAOK2,TIAM1,TNFRSF11A,TPD52L1,TWIST1,ZKSCAN3,ZNF365 |
| GO_RENAL_TUBULE_DEVELOPMENT | 1.7e-06 | 3.4e-05 | 1125 | 96 | 12 | CITED1,COL4A1,CTNNBIP1,FAT4,GLI3,IRX2,LAMA5,LGR4,PBX1,PTCH1,STAT1,WNT11 |
| GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | 1.8e-06 | 3.5e-05 | 1125 | 151 | 15 | CITED1,COL4A1,CTNNBIP1,ESR1,FAT4,GLI2,GLI3,LAMA1,LAMA5,LGR4,LRP5,PBX1,PLXND1,PTCH1,TGFBR2 |
| GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 1.9e-06 | 3.6e-05 | 1125 | 401 | 26 | AGR2,ANK3,CYTH3,DENND6A,DISC1,EFNB2,EPB41L4B,FN1,FRMD5,FSTL3,GLI2,GLI3,IL18,ITGA3,ITGB1BP1,JUP,KDR,KLRC4-KLRK1,PRKCA,PTK2B,RAG1,TGFBR2,TNFSF14,VAV3,VSIR,ZP3 |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 2.0e-06 | 3.9e-05 | 1125 | 353 | 24 | ABCD2,ABCD3,ACSM2B,ADIPOQ,AMACR,ASAH2,CHST12,CSAD,DHFR2,ELOVL6,ERLIN2,FADS3,HSD17B8,LPL,MECR,MLYCD,MRI1,MTHFR,NR1H4,PTGS1,SCAP,SLC25A12,SRR,UROS |
| GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 2.0e-06 | 3.8e-05 | 1125 | 172 | 16 | EPB41L4B,FOXP1,GPLD1,HIF1A,IQSEC1,ITGA3,ITGB1BP1,JCAD,KDR,MAPRE2,PRKCA,PTK2B,ROCK2,SCARB1,SEMA5A,TGFBR2 |
| GO_REGULATION_OF_ION_TRANSPORT | 2.0e-06 | 3.8e-05 | 1125 | 699 | 37 | ADORA1,ADRB2,ANK3,ARRB2,ATP7A,ATPSCKMT,CLCN2,DLG3,DLG4,FGF12,GJA1,GNB5,GOPC,GPD1L,HSPA2,KCNJ1,LRRC7,MAOB,MINK1,P2RX1,PKP2,PRKACA,PTK2B,RNF207,SCN1B,SLC9A3R1,SNCA,STIM2,STXBP1,TCAF1,TMEM37,TNFRSF11A,TPCN1,TWIST1,UCN,WWP2,YWHAH |
| GO_SENSORY_ORGAN_MORPHOGENESIS | 2.0e-06 | 3.8e-05 | 1125 | 258 | 20 | BCR,CDON,CHRNA9,FAT1,FZD3,GDF11,GLI2,GLI3,GRHL3,HIF1A,LHFPL5,LRP5,NAGLU,PDZD7,PTPRM,SKI,SLC9A3R1,TENM3,TFAP2A,TWIST1 |
| GO_PEROXISOME_ORGANIZATION | 2.1e-06 | 3.9e-05 | 1125 | 81 | 11 | ABCD3,AMACR,CRAT,CROT,GSTK1,MLYCD,NUDT7,PEX1,PEX2,PEX7,PLAAT3 |
| GO_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | 2.1e-06 | 4.0e-05 | 1125 | 259 | 20 | ARHGAP28,ASAP3,CAPZA2,CDC42EP3,EVL,GBA2,ID1,IQGAP2,ITGB1BP1,LIMK1,LPAR1,PICK1,PPM1E,PTK2B,RGCC,ROCK2,SEMA5A,SPIRE2,TMOD2,WNT11 |
| GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 2.2e-06 | 4.1e-05 | 1125 | 215 | 18 | ADIPOQ,APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ENPP1,FOXO1,GPLD1,IRS1,LPL,NR1H4,PDE3B,SESN3,SORL1,SREBF1,STAT1,STXBP4 |
| GO_TEMPERATURE_HOMEOSTASIS | 2.2e-06 | 4.1e-05 | 1125 | 173 | 16 | ADIPOQ,ADORA1,ADRB1,ADRB2,ELOVL6,FOXO1,GJA1,ID1,IL18,IRF4,LGR4,NOVA1,NOVA2,PCTP,STK11,TNFRSF11A |
| GO_MESENCHYMAL_CELL_DIFFERENTIATION | 2.3e-06 | 4.4e-05 | 1125 | 216 | 18 | BCL9L,ERBB4,FN1,HIF1A,LAMA5,NRTN,RFLNB,RGCC,S100A4,SEMA3F,SEMA4F,SEMA4G,SEMA6D,STAT1,TGFBR2,TIAM1,TWIST1,WNT11 |
| GO_MUSCLE_TISSUE_DEVELOPMENT | 2.4e-06 | 4.4e-05 | 1125 | 406 | 26 | ARRB2,BCL9L,BVES,CDON,CSRP1,CXADR,EFNB2,ERBB4,GJA1,GJC1,HEG1,HLF,HMG20B,JARID2,LMNA,MRTFB,MYH10,MYORG,PKP2,POGLUT1,PPARA,PTCD2,SKI,TGFBR2,TWIST1,XIRP2 |
| GO_ACIDIC_AMINO_ACID_TRANSPORT | 2.5e-06 | 4.6e-05 | 1125 | 67 | 10 | ADORA1,GJA1,PPFIA3,PRAF2,RAB3A,SLC25A12,SLC25A18,SNCA,STXBP1,UNC13B |
| GO_MUSCLE_ORGAN_DEVELOPMENT | 2.5e-06 | 4.6e-05 | 1125 | 407 | 26 | ARRB2,BASP1,BCL9L,BVES,CDON,EFNB2,ERBB4,FGFRL1,FZD1,GJA1,HEG1,HLF,HMG20B,JARID2,LAMA5,MRTFB,MYORG,PKP2,PPARA,PTCD2,SKI,TGFBR2,TWIST1,USP2,XIRP2,ZBTB42 |
| GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 2.7e-06 | 5.0e-05 | 1125 | 334 | 23 | ADCY1,ADCY9,ADORA1,ADRB2,ARRB1,CARD10,GAS6,IL18,ITGB1BP1,LPAR1,MAP3K13,MAP3K5,MAP4K2,MINK1,PRKACA,PTK2B,RGCC,SHC2,STK11,TAOK2,TGFBR2,UCN,WNT11 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 2.8e-06 | 5.2e-05 | 1125 | 1036 | 48 | ADRB2,AGO1,ARHGAP28,ATF7IP,ATP5F1D,BBS10,BRF1,CAPZA2,CDC42EP3,COX16,CPTP,ERCC2,ESR1,EVL,GBA2,GEMIN8,H1-0,H2BC4,H3C10,H3C12,H4C9,HIP1,HLA-DMA,IMMP2L,IQGAP2,NAP1L3,NAP1L5,NDUFB3,NIN,PET100,PICK1,PTK2B,RAB3A,SMAD6,SMYD3,SNAP47,SNCA,SPIRE2,STXBP1,SURF1,TIAM1,TMOD2,TRIM6,TSPYL1,TTC19,TUBG2,UNC13B,VPS18 |
| GO_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | 3.0e-06 | 5.5e-05 | 1125 | 157 | 15 | ADORA1,ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CLN5,DMXL2,SCNN1A,SCNN1G,SLC12A5,SLC4A4,SLC9A6,SLC9A7,TMEM175 |
| GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT | 3.0e-06 | 5.6e-05 | 1125 | 101 | 12 | ANK3,ARL3,BBS2,CCDC91,DOP1B,EXOC2,GGA3,GOPC,LLGL1,RAB26,SORL1,SORT1 |
| GO_NEGATIVE_REGULATION_OF_SECRETION | 3.1e-06 | 5.8e-05 | 1125 | 243 | 19 | ADIPOQ,ADORA1,BCR,CD200,CPTP,FN1,GAS6,GJA1,IDH2,IRS1,LGR4,MAOB,NR1H4,RAB11FIP1,RGCC,SERGEF,SNCA,SREBF1,UCN |
| GO_DRUG_METABOLIC_PROCESS | 3.2e-06 | 5.8e-05 | 1125 | 600 | 33 | ACPP,ADH4,ALDH3A2,ALDH5A1,ATP5F1D,ATP7A,ATPSCKMT,BCHE,BTD,CHST12,CKMT1A,CKMT1B,CYP2R1,CYP2U1,DDAH1,DHFR2,ENPP1,HLCS,KLRC4-KLRK1,MAOB,MAT2A,MAT2B,MMAA,MRI1,MT-CO2,MTHFR,PTK2B,ROCK2,SLC25A12,SLC46A1,SNCA,SRR,SULT1A4 |
| GO_MUSCLE_CONTRACTION | 3.2e-06 | 5.8e-05 | 1125 | 362 | 24 | ADORA1,ADRB2,BBS2,BDKRB2,CHRM3,CHRNE,FGF12,GJA1,GJC1,GPD1L,HSPB6,HTR1D,JUP,LTB4R,P2RX1,PKP2,PRKACA,RNF207,ROCK2,SCN1B,SULF1,TMOD2,UCN,VCL |
| GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY | 3.4e-06 | 6.2e-05 | 1125 | 139 | 14 | APPL1,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,ENPP1,FOXO1,GPLD1,IRS1,NR1H4,SESN3,SORL1,SREBF1,STXBP4 |
| GO_REGULATION_OF_CELL_SIZE | 3.4e-06 | 6.2e-05 | 1125 | 179 | 16 | ATP7A,DISC1,EPHA7,FN1,LIMK1,MAP3K13,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC12A5,SLC9A3R1,UCN,VAV3 |
| GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 3.4e-06 | 6.2e-05 | 1125 | 200 | 17 | ABCD2,ADIPOQ,CLCN2,DGAT2,ELOVL6,ERLIN2,FITM2,GPLD1,IGFBP7,NR1H4,PMVK,SCAP,SCARB1,SIRT3,SREBF1,TM7SF2,ZP3 |
| GO_OSTEOBLAST_DIFFERENTIATION | 3.6e-06 | 6.6e-05 | 1125 | 223 | 18 | CITED1,CTNNBIP1,FAM20C,FZD1,GLI2,GLI3,ID1,LGR4,LRP5,MEN1,PRKACA,PTCH1,SKI,SMAD6,SMOC1,TWIST1,WNT11,ZHX3 |
| GO_RESPIRATORY_SYSTEM_DEVELOPMENT | 3.6e-06 | 6.5e-05 | 1125 | 201 | 17 | AGR2,ATP7A,BASP1,FGFRL1,FSTL3,GLI2,GLI3,HEG1,ID1,ITGA3,LAMA1,LAMA5,RAB3A,SKI,SREBF1,TGFBR2,WNT11 |
| GO_PEROXISOMAL_TRANSPORT | 3.7e-06 | 6.8e-05 | 1125 | 70 | 10 | ABCD3,AMACR,CRAT,CROT,GSTK1,MLYCD,NUDT7,PEX1,PEX2,PEX7 |
| GO_RETINAL_BLOOD_VESSEL_MORPHOGENESIS | 3.7e-06 | 6.7e-05 | 1125 | 6 | 4 | COL4A1,FZD4,LAMA1,LRP5 |
| GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 4.2e-06 | 7.6e-05 | 1125 | 56 | 9 | ADIPOQ,BASP1,CITED1,FAT4,GLI3,LGR4,PRKX,PTCH1,STAT1 |
| GO_COAGULATION | 4.2e-06 | 7.5e-05 | 1125 | 343 | 23 | ARRB1,ARRB2,C1GALT1C1,CAPZA2,CBX5,CD9,CSRP1,F2RL2,F8,GAS6,GGCX,H3C10,H3C12,HMG20B,ITPK1,P2RX1,PRKACA,PRKCA,PRKCH,SERPING1,STXBP1,VAV3,VCL |
| GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | 4.2e-06 | 7.6e-05 | 1125 | 248 | 19 | APPL1,ARRB2,BCL9L,CITED1,COL4A2,DUSP22,HTRA1,HYAL2,ID1,ITGA3,MEN1,NREP,PARD6A,PEG10,ROCK2,SKI,SMAD6,STK11,TGFBR2 |
| GO_DEFENSE_RESPONSE | 4.4e-06 | 7.8e-05 | 1125 | 1765 | 70 | ABCD2,ADCY1,ADIPOQ,ADORA1,APPL1,ARRB2,BCR,BDKRB2,CAPZA2,CD200,CFI,CHST2,CITED1,CTNNBIP1,EIF2AK1,ESR1,EVL,F8,FN1,FOXP1,GJA1,H2BC4,HIF1A,HTRA1,HYAL2,IFI30,IFNAR2,IGHV4-34,IL18,IRF4,KLRC2,KLRC4-KLRK1,KLRD1,LGALS3BP,LGR4,LILRB3,LPL,LTB4R,LY75,MAP3K5,MAP4K2,MUC2,NLRP1,NLRP2,NR1H4,P2RX1,PPARA,PRKACA,PTGS1,PTK2B,RAB7B,RAG1,SAA2,SARM1,SERPING1,SGMS1,SNCA,STAT1,STXBP1,STXBP4,TNFRSF11A,TRIM34,TRIM44,TRIM6,TSPAN6,UCN,UNC13B,UNC93B1,VGF,ZP3 |
| GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 4.4e-06 | 7.8e-05 | 1125 | 204 | 17 | ADIPOQ,CD200,CPTP,FN1,GAS6,GOPC,IDH2,IRS1,ITGB1BP1,LGR4,NR1H4,PKIA,RAB11FIP1,RGCC,SERGEF,SREBF1,WWP2 |
| GO_NEURAL_TUBE_FORMATION | 4.5e-06 | 8.1e-05 | 1125 | 105 | 12 | FZD1,FZD3,GRHL3,HIF1A,LUZP1,MTHFR,PRICKLE1,PRKACA,PTCH1,SKI,SPINT2,TWIST1 |
| GO_MITOCHONDRION_ORGANIZATION | 4.6e-06 | 8.3e-05 | 1125 | 528 | 30 | ADCK1,ARRB2,ATG2A,ATP5F1D,ATP7A,COX16,CXADR,DNM3,ERBB4,HIF1A,IMMP2L,KDR,LMNA,NDUFB3,PET100,PTCD2,RAB3A,RTL10,SIRT3,SLC25A46,SNCA,SPG7,SREBF1,SURF1,SYNJ2BP,TMEM14A,TRAK2,TTC19,TYMP,YWHAH |
| GO_POSITIVE_REGULATION_OF_AXONOGENESIS | 4.7e-06 | 8.3e-05 | 1125 | 88 | 11 | DISC1,FN1,LIMK1,MAP3K13,METRN,NIN,PLXND1,ROBO2,SEMA5A,STK11,TIAM1 |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 4.8e-06 | 8.5e-05 | 1125 | 371 | 24 | CITED1,CMAHP,CTNNBIP1,CXXC4,DISC1,DIXDC1,ESR1,FOXO1,FZD1,GLI3,ITGA3,JUP,LGR4,LYPD6,PRICKLE1,RECK,SEMA5A,SKI,SLC9A3R1,SOST,STK11,SULF1,TIAM1,WNT11 |
| GO_RECEPTOR_CLUSTERING | 4.9e-06 | 8.6e-05 | 1125 | 57 | 9 | AGRN,DLG3,DLG4,GLRB,GPHN,ITGB1BP1,LRRC7,PICK1,SYNJ2BP |
| GO_INSULIN_SECRETION | 5.0e-06 | 8.8e-05 | 1125 | 206 | 17 | ARRB1,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,PFKFB2,PRKCA,RAPGEF4,SIRT3,SNX19,SREBF1,STXBP4,TIAM1,TM7SF3,VGF |
| GO_PEPTIDE_HORMONE_SECRETION | 5.0e-06 | 8.9e-05 | 1125 | 251 | 19 | ARRB1,EXOC3L1,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,PFKFB2,PRKCA,RAPGEF4,SIRT3,SNX19,SREBF1,STXBP4,TIAM1,TM7SF3,UCN,VGF |
| GO_DENDRITE_MORPHOGENESIS | 5.2e-06 | 9.1e-05 | 1125 | 144 | 14 | ADAM10,CELSR2,DLG4,DNM3,FBXW8,ID1,MINK1,SARM1,STK11,TAOK2,TIAM1,TRAK2,YWHAH,ZNF365 |
| GO_REGULATION_OF_HEMOPOIESIS | 5.2e-06 | 9.1e-05 | 1125 | 477 | 28 | ADIPOQ,AGO1,ASH2L,CTNNBIP1,FOXP1,FSTL3,GAS6,GLI2,GLI3,H3C10,H3C12,H4C9,HIF1A,IL18,IRF4,LILRB3,LMO2,PRKCA,PTK2B,PURB,RAB7B,RAG1,SOX13,STAT1,TGFBR2,TNRC6C,TRIM58,VSIR |
| GO_EPITHELIAL_CELL_DEVELOPMENT | 5.3e-06 | 9.2e-05 | 1125 | 207 | 17 | ADIPOQ,ARHGEF26,BCL11B,CCM2,DNASE1L2,ESR1,FAT1,HEG1,HIF1A,ID1,LHFPL5,PDZD7,PECAM1,ROCK2,SLC9A3R1,SOX18,SPINT2 |
| GO_PROTEIN_CATABOLIC_PROCESS | 5.3e-06 | 9.2e-05 | 1125 | 938 | 44 | ABHD13,ABHD17A,ANKIB1,AP2A2,ARRB1,ARRB2,C17orf97,CLN5,DISC1,ENC1,ERLIN2,F8A1,F8A3,FBXL16,FBXL4,FBXO21,FBXO33,FBXW8,FOXO1,GFAP,GGA3,GJA1,GPLD1,HECTD3,MAGEF1,PCYOX1L,PRICKLE1,PRKACA,PTK2B,RAB26,RMND5B,RNF123,RNFT1,SNCA,SNX1,SORL1,TMTC3,TRIM58,UBE2D4,UBE2L6,USP2,USP48,WDR91,WWP2 |
| GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 5.3e-06 | 9.2e-05 | 1125 | 348 | 23 | ADIPOQ,ANK3,ATPSCKMT,B3GAT3,BVES,GAS6,GLI3,HYAL2,ITGB1BP1,JUP,LDLRAP1,MTCL1,PKIA,PRKACA,PTPN14,REEP2,REEP6,SORL1,SREBF1,STXBP1,TCAF1,TRIM58,UHMK1 |
| GO_STEM_CELL_DIFFERENTIATION | 5.3e-06 | 9.2e-05 | 1125 | 252 | 19 | BCHE,ERBB4,ERCC2,ESR1,FN1,FZD1,HIF1A,JARID2,LAMA5,LMO2,NRTN,PRICKLE1,SEMA3F,SEMA4F,SEMA4G,SEMA6D,SOX18,TRIM6,TWIST1 |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 5.3e-06 | 9.2e-05 | 1125 | 348 | 23 | APPL1,ARRB2,BCL9L,CITED1,DUSP22,FSTL3,FZD1,GDF11,HTRA1,ID1,ITGA3,MEN1,NREP,PARD6A,PEG10,SKI,SKOR1,SMAD6,SORL1,SOST,STK11,SULF1,TGFBR2 |
| GO_COFACTOR_BIOSYNTHETIC_PROCESS | 5.6e-06 | 9.7e-05 | 1125 | 230 | 18 | COQ8B,DHFR2,ELOVL6,GPHN,HSD17B8,IDH2,MAOB,MAT2A,MAT2B,MLYCD,MMAA,MOCS1,MOCS3,MPC1,MT-CO2,SLC25A39,SNCA,UROS |
| GO_TELENCEPHALON_DEVELOPMENT | 5.6e-06 | 9.7e-05 | 1125 | 253 | 19 | BBS2,BCL11B,CDON,DISC1,DIXDC1,ERBB4,FAT4,GLI3,GNG12,HIF1A,LPAR1,MYH10,NIN,PPP1R9B,ROBO2,RTN4R,SKI,SUN1,TRAPPC9 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 5.8e-06 | 9.9e-05 | 1125 | 534 | 30 | ARHGAP28,ARHGEF19,ASAP3,CAPZA2,CDC42EP3,DIXDC1,EVL,GAS2L1,GBA2,GRHL3,ID1,IQGAP2,ITGB1BP1,LIMK1,LPAR1,MAPRE2,NIN,PICK1,PPM1E,PTK2B,RGCC,RHOBTB1,ROCK2,SEMA5A,SNCA,SPIRE2,STMN3,TAOK2,TMOD2,WNT11 |
| GO_CELLULAR_RESPIRATION | 5.9e-06 | 1.0e-04 | 1125 | 187 | 16 | ALDH5A1,ATP5F1D,DHTKD1,ETFDH,HIF1A,IDH2,IMMP2L,MT-CO2,NDUFB3,SIRT3,SLC25A12,SLC25A18,SLC25A23,SNCA,SURF1,UCN |
| GO_REGULATION_OF_SYNAPTIC_PLASTICITY | 5.9e-06 | 1.0e-04 | 1125 | 187 | 16 | ADCY1,ADORA1,CRTC1,DLG4,MPP2,NPTN,PICK1,PPFIA3,PTK2B,RAB3A,SNAP47,SNCA,SORCS2,STXBP1,UNC13B,YWHAH |
| GO_PROTEIN_TARGETING | 6.1e-06 | 1.0e-04 | 1125 | 428 | 26 | ADORA1,AMACR,ANK3,CRAT,CROT,GSTK1,IMMP2L,ITGB1BP1,MLYCD,MTCL1,NUDT7,PEX1,PEX2,PEX7,SORL1,SREBF1,STXBP4,SYNJ2BP,TAOK2,TCAF1,TRAK2,TRAM1L1,TRAM2,ZDHHC14,ZDHHC20,ZDHHC24 |
| GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 6.2e-06 | 1.1e-04 | 1125 | 74 | 10 | ANK3,CXADR,FGF12,GJA1,GJC1,GPD1L,JUP,PKP2,RNF207,SCN1B |
| GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 6.2e-06 | 1.1e-04 | 1125 | 278 | 20 | ALDH5A1,ATP5F1D,DHTKD1,ENPP1,ETFDH,HIF1A,IDH2,IMMP2L,IRS1,MRAP2,MT-CO2,NDUFB3,PYGB,SIRT3,SLC25A12,SLC25A18,SLC25A23,SNCA,SURF1,UCN |
| GO_VESICLE_LOCALIZATION | 6.5e-06 | 1.1e-04 | 1125 | 210 | 17 | BBS2,DNM3,F8,F8A1,F8A3,FYCO1,KIF3A,MAP4K2,PCDH17,RAB3A,SEPTIN5,SNCA,TRAK2,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9 |
| GO_CHEMICAL_SYNAPTIC_TRANSMISSION_POSTSYNAPTIC | 6.7e-06 | 1.1e-04 | 1125 | 109 | 12 | ADORA1,ADRB2,ARRB2,CHRNA9,CHRNE,DLG4,GLRB,MPP2,P2RX1,PTK2B,SNCA,UNC13B |
| GO_DEVELOPMENTAL_CELL_GROWTH | 6.7e-06 | 1.1e-04 | 1125 | 233 | 18 | DISC1,EPHA7,FN1,LIMK1,MAP3K13,NIN,PPARA,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A6,STK11,TGFBR2,TIAM1,VCL |
| GO_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | 6.7e-06 | 1.1e-04 | 1125 | 233 | 18 | ABCD2,ABCD3,ACSM2B,ADIPOQ,AMACR,ASAH2,CHST12,ELOVL6,ERLIN2,FADS3,HSD17B8,LPL,MECR,MLYCD,NR1H4,PTGS1,SCAP,SRR |
| GO_NEURON_DEATH | 6.7e-06 | 1.1e-04 | 1125 | 353 | 23 | ADORA1,ARRB1,ARRB2,CASP9,CD200,CITED1,EFNB2,EPHA7,FZD1,HIF1A,LIG4,MAP3K5,NLRP1,PPARA,PTK2B,SARM1,SNCA,SORL1,STXBP1,SULT1A4,TBC1D24,TFAP2A,UCN |
| GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 6.7e-06 | 1.1e-04 | 1125 | 353 | 23 | ADIPOQ,APBB1,ARRB2,CTC1,ERCC2,ERCC4,EYA4,FBH1,GJA1,H1-0,MAGEF1,MEN1,NUDT16,PARM1,PTK2B,RADX,RGCC,SLX4,SPIDR,SPIRE2,TWIST1,YLPM1,ZNF365 |
| GO_RESPONSE_TO_MECHANICAL_STIMULUS | 6.9e-06 | 1.1e-04 | 1125 | 211 | 17 | CHRNA9,CRADD,GJA1,HABP4,JUP,LHFPL5,LRP11,PDZD7,PTCH1,PTK2B,SOST,STAT1,SUN1,TGFBR2,TNFSF14,UCN,WNT11 |
| GO_EPITHELIAL_CELL_MORPHOGENESIS | 7.3e-06 | 1.2e-04 | 1125 | 33 | 7 | ARHGEF26,BCL11B,FAT1,HEG1,ID1,PECAM1,SPINT2 |
| GO_METANEPHROS_DEVELOPMENT | 7.3e-06 | 1.2e-04 | 1125 | 92 | 11 | ADIPOQ,BASP1,CITED1,FAT4,GDF11,GLI3,IRX2,LGR4,PTCH1,ROBO2,STAT1 |
| GO_REGULATION_OF_BIOMINERALIZATION | 7.3e-06 | 1.2e-04 | 1125 | 92 | 11 | ADRB2,ENPP1,FAM20C,GAS6,HIF1A,ODAPH,PTK2B,RFLNB,ROCK2,TFAP2A,TWIST1 |
| GO_VESICLE_ORGANIZATION | 7.3e-06 | 1.2e-04 | 1125 | 330 | 22 | CHMP7,DLG4,DNM3,F8,PHETA1,RAB3A,RAB7B,SNAP47,SNCA,SNX10,SNX19,SORT1,STX17,STXBP1,TMEM175,TRAPPC1,TRAPPC2,TRAPPC5,TRAPPC9,UNC13B,VAV3,VPS18 |
| GO_AMINOGLYCAN_METABOLIC_PROCESS | 7.4e-06 | 1.2e-04 | 1125 | 169 | 15 | AGRN,B3GAT3,B4GAT1,CEMIP2,CHST12,CHST2,CHST7,CHSY3,GLCE,HS3ST1,HYAL2,NAGLU,NDST3,SDC3,XYLT2 |
| GO_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 7.4e-06 | 1.2e-04 | 1125 | 486 | 28 | ADRB2,ANK3,ATP7A,ATPSCKMT,CLCN2,DLG3,DLG4,FGF12,GNB5,GOPC,GPD1L,HSPA2,KCNJ1,LRRC7,MINK1,PRKACA,PTK2B,RNF207,SCN1B,SLC9A3R1,SNCA,STIM2,TCAF1,TMEM37,TPCN1,TWIST1,WWP2,YWHAH |
| GO_TIGHT_JUNCTION_ORGANIZATION | 7.6e-06 | 1.2e-04 | 1125 | 60 | 9 | CLDN9,GJA1,MPP7,PARD6A,PECAM1,PRKACA,PRKCH,ROCK2,WNT11 |
| GO_IMMUNE_EFFECTOR_PROCESS | 7.7e-06 | 1.3e-04 | 1125 | 1267 | 54 | ACPP,ADAM10,AP2A2,APPL1,ARRB2,ATP6V0A1,ATP7A,BCR,CDH17,CFI,COMMD3,DUSP22,FOXP1,GHDC,GM2A,HTRA1,HYAL2,IFNAR2,IGHV4-34,IL18,IQGAP2,IRF4,ITM2A,JUP,KLRC2,KLRC4-KLRK1,KLRD1,LFNG,LIG4,LILRB3,LIMK1,LRRC7,MVP,NBEAL2,P2RX1,PECAM1,PTK2B,PYGB,RAB3A,RAB3D,RGCC,SCART1,SERPING1,STAT1,STXBP1,TRAPPC1,TRIM34,TRIM44,TRIM6,TSPAN6,UNC93B1,VAV3,VCL,ZP3 |
| GO_TUBE_FORMATION | 7.7e-06 | 1.3e-04 | 1125 | 149 | 14 | FZD1,FZD3,GRHL3,HIF1A,IRX2,ITGB1BP1,LUZP1,MTHFR,PRICKLE1,PRKACA,PTCH1,SKI,SPINT2,TWIST1 |
| GO_EMBRYONIC_ORGAN_DEVELOPMENT | 7.8e-06 | 1.3e-04 | 1125 | 434 | 26 | BCR,CHRNA9,CITED1,ERCC2,FBXW8,FZD3,GJB5,GLI2,GLI3,GRHL3,HIF1A,KDR,LHFPL5,NAGLU,PBX1,PDZD7,PLCD3,PTCH1,RNF207,SLC9A3R1,SOX18,SPINT2,TFAP2A,TGFBR2,TWIST1,WNT11 |
| GO_CARDIAC_VENTRICLE_DEVELOPMENT | 8.2e-06 | 1.3e-04 | 1125 | 130 | 13 | FGFRL1,FZD1,HEG1,HIF1A,LUZP1,PKP2,PTCD2,ROBO2,SMAD6,SMARCD3,TGFBR2,WNT11,XIRP2 |
| GO_LIPOPROTEIN_METABOLIC_PROCESS | 8.2e-06 | 1.3e-04 | 1125 | 130 | 13 | ABHD13,ABHD17A,ATG10,DGAT2,GPLD1,PIGM,PIGN,PIGX,PPARA,ZDHHC14,ZDHHC20,ZDHHC24,ZDHHC8 |
| GO_REGULATION_OF_HORMONE_SECRETION | 8.3e-06 | 1.4e-04 | 1125 | 260 | 19 | ADIPOQ,ADORA1,ARRB1,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,PFKFB2,PRKCA,RAB11FIP1,RAPGEF4,SIRT3,SREBF1,STXBP4,TIAM1,TM7SF3,UCN |
| GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 8.3e-06 | 1.3e-04 | 1125 | 192 | 16 | APPL1,ARRB2,BCL9L,CITED1,DUSP22,HTRA1,ID1,ITGA3,MEN1,NREP,PARD6A,PEG10,SKI,SMAD6,STK11,TGFBR2 |
| GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 8.7e-06 | 1.4e-04 | 1125 | 61 | 9 | EVL,ID1,ITGB1BP1,LIMK1,LPAR1,PPM1E,RGCC,ROCK2,WNT11 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 8.7e-06 | 1.4e-04 | 1125 | 61 | 9 | ARPP19,DGAT2,FOXO1,GPLD1,IRS1,PFKFB2,PPARA,SLC25A12,SNCA |
| GO_REGULATION_OF_CELL_CELL_ADHESION | 8.9e-06 | 1.4e-04 | 1125 | 411 | 25 | ADIPOQ,ANK3,CD9,CELSR2,DENND6A,DUSP22,EFNB2,EPHA7,FSTL3,GLI2,GLI3,IL18,KLRC4-KLRK1,LRFN3,MINK1,PPARA,PRKCA,RAG1,RGCC,SPINT2,TENM3,TGFBR2,TNFSF14,VSIR,ZP3 |
| GO_CARDIAC_CHAMBER_DEVELOPMENT | 9.1e-06 | 1.5e-04 | 1125 | 172 | 15 | FGFRL1,FZD1,HEG1,HIF1A,LUZP1,MYH10,PKP2,PLXND1,PTCD2,ROBO2,SMAD6,SMARCD3,TGFBR2,WNT11,XIRP2 |
| GO_ESTABLISHMENT_OR_MAINTENANCE_OF_BIPOLAR_CELL_POLARITY | 9.3e-06 | 1.5e-04 | 1125 | 47 | 8 | DLG3,FAT1,LAMA1,LRRC7,MTCL1,SLC9A3R1,SYNJ2BP,WNT11 |
| GO_LEUKOCYTE_DIFFERENTIATION | 9.4e-06 | 1.5e-04 | 1125 | 520 | 29 | ADIPOQ,ATP7A,BCL11B,CDH17,CTNNBIP1,EIF2AK1,FAM20C,FOXP1,FSTL3,GAS6,GLI2,GLI3,IL18,IRF4,ITM2A,JAG2,LFNG,LIG4,LILRB3,PRKCA,PTK2B,RAG1,SATB1,SNX10,SOX13,STK11,TGFBR2,TNFRSF11A,VSIR |
| GO_PROTEIN_COMPLEX_OLIGOMERIZATION | 9.6e-06 | 1.5e-04 | 1125 | 493 | 28 | ACPP,ADIPOQ,ALDH5A1,CRTC1,EVL,FGFRL1,GJA1,GLRB,GOPC,H3C10,H3C12,H4C9,HSD17B8,JUP,KHDRBS3,MARCKS,MAT2A,MPP2,P2RX1,RASEF,SKI,SNCA,SORL1,SRR,TMEM120B,TRIM34,TRIM6,UXS1 |
| GO_POSITIVE_REGULATION_OF_FATTY_ACID_OXIDATION | 9.7e-06 | 1.5e-04 | 1125 | 14 | 5 | ABCD2,IRS1,MLYCD,PPARA,TWIST1 |
| GO_DICARBOXYLIC_ACID_TRANSPORT | 9.9e-06 | 1.6e-04 | 1125 | 95 | 11 | ADORA1,GJA1,PPFIA3,PRAF2,RAB3A,SLC25A12,SLC25A18,SLC46A1,SNCA,STXBP1,UNC13B |
| GO_EPITHELIAL_TUBE_FORMATION | 1.0e-05 | 1.7e-04 | 1125 | 133 | 13 | FZD1,FZD3,GRHL3,HIF1A,IRX2,LUZP1,MTHFR,PRICKLE1,PRKACA,PTCH1,SKI,SPINT2,TWIST1 |
| GO_ODONTOGENESIS | 1.0e-05 | 1.7e-04 | 1125 | 133 | 13 | BCL11B,FAM20C,FOXO1,GLI2,GLI3,HTRA1,JAG2,LAMA5,ODAPH,PPARA,SNX10,TFAP2A,TWIST1 |
| GO_ADAPTIVE_THERMOGENESIS | 1.1e-05 | 1.8e-04 | 1125 | 154 | 14 | ADIPOQ,ADRB1,ADRB2,ELOVL6,GJA1,ID1,IL18,IRF4,LGR4,NOVA1,NOVA2,PCTP,SORL1,STK11 |
| GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | 1.1e-05 | 1.7e-04 | 1125 | 114 | 12 | AGRN,B3GAT3,B4GAT1,CHST12,CHST2,CHST7,CHSY3,GLCE,HS3ST1,NDST3,SDC3,XYLT2 |
| GO_CARBOHYDRATE_HOMEOSTASIS | 1.1e-05 | 1.7e-04 | 1125 | 241 | 18 | ADIPOQ,ARRB1,FOXO1,GAS6,GPLD1,HIF1A,IRS1,LRP5,MEN1,NR1H4,PRKACA,PTCH1,SESN3,STK11,STXBP4,TIAM1,UNC13B,VGF |
| GO_METAL_ION_HOMEOSTASIS | 1.1e-05 | 1.8e-04 | 1125 | 667 | 34 | ADORA1,ANK3,ATP7A,ATP7B,BDKRB2,CHRNA9,CLDN16,DISC1,DLG4,EIF2AK1,ESR1,F2RL2,GJA1,GPR157,HIF1A,HYAL2,LPAR1,NPTN,P2RX1,PLCB2,PLCD3,PRKACA,PTK2B,SCNN1A,SCNN1G,SLC12A5,SLC25A23,SLC30A4,SLC46A1,SNCA,SNX10,STIM2,TMTC2,TPCN1 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 1.1e-05 | 1.8e-04 | 1125 | 1030 | 46 | ADORA1,AGR2,ARRB1,ARRB2,ASAH2,BCL11B,BDKRB2,CD200,CITED1,EYA4,FOXO1,FOXP1,FZD1,FZD3,GAS6,GLI2,GLI3,HIF1A,HSPB6,ID1,KDR,LIG4,LMNA,MEIS3,MIEN1,NAA38,NR1H4,PPARA,PRKCA,PRKCH,PTK2B,RAG1,SEMA5A,SERPINB13,SMAD6,SNCA,SORL1,STXBP1,SULT1A4,TFAP2A,TM7SF3,TMEM14A,TNFSF14,TWIST1,UCN,WNT11 |
| GO_PLATELET_ACTIVATION | 1.1e-05 | 1.8e-04 | 1125 | 154 | 14 | ARRB1,ARRB2,C1GALT1C1,CD9,CSRP1,F2RL2,F8,GAS6,P2RX1,PRKCA,PRKCH,STXBP1,VAV3,VCL |
| GO_REGULATION_OF_CHOLESTEROL_METABOLIC_PROCESS | 1.1e-05 | 1.8e-04 | 1125 | 63 | 9 | DGAT2,ELOVL6,ERLIN2,LDLRAP1,NR1H4,PMVK,SCAP,SREBF1,TM7SF2 |
| GO_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS | 1.1e-05 | 1.7e-04 | 1125 | 96 | 11 | ABCD2,ADIPOQ,DGAT2,ERLIN2,IRS1,MLYCD,PPARA,SCAP,SNCA,SREBF1,TWIST1 |
| GO_REGULATION_OF_INSULIN_SECRETION | 1.1e-05 | 1.8e-04 | 1125 | 175 | 15 | ARRB1,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,PFKFB2,PRKCA,RAPGEF4,SIRT3,SREBF1,STXBP4,TIAM1,TM7SF3 |
| GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 1.1e-05 | 1.8e-04 | 1125 | 242 | 18 | BCL9L,CITED1,FSTL3,FZD1,GDF11,HTRA1,ITGA3,MEN1,NREP,PEG10,SKI,SKOR1,SMAD6,SORL1,SOST,STK11,SULF1,TGFBR2 |
| GO_EAR_DEVELOPMENT | 1.2e-05 | 1.8e-04 | 1125 | 220 | 17 | ADAM10,ATP8B1,BCR,CCM2,CHRNA9,FAT4,FZD3,GLI2,GLI3,GRHL3,JAG2,LHFPL5,NAGLU,PDZD7,SLC9A3R1,TFAP2A,TWIST1 |
| GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 1.2e-05 | 1.9e-04 | 1125 | 97 | 11 | ARHGAP28,ASAP3,EVL,ID1,ITGB1BP1,LIMK1,LPAR1,PPM1E,RGCC,ROCK2,WNT11 |
| GO_RENAL_FILTRATION | 1.2e-05 | 1.9e-04 | 1125 | 24 | 6 | ADORA1,GAS6,GJA1,ITGA3,MCAM,SULF1 |
| GO_APICAL_JUNCTION_ASSEMBLY | 1.3e-05 | 2.0e-04 | 1125 | 64 | 9 | GJA1,MPP7,PARD6A,PECAM1,PRKACA,PRKCH,ROCK2,VCL,WNT11 |
| GO_NEGATIVE_REGULATION_OF_GTPASE_ACTIVITY | 1.3e-05 | 2.0e-04 | 1125 | 49 | 8 | ARRB1,ARRB2,GPSM1,IQGAP2,KLRC4-KLRK1,RASA4,SH3BP4,TNK2 |
| GO_HOMOTYPIC_CELL_CELL_ADHESION | 1.4e-05 | 2.2e-04 | 1125 | 81 | 10 | ANK3,CD9,CSRP1,CXADR,GAS6,JUP,PKP2,PRKCA,STXBP1,VCL |
| GO_SENSORY_SYSTEM_DEVELOPMENT | 1.4e-05 | 2.1e-04 | 1125 | 369 | 23 | BCL11B,CDON,CLCN2,COL4A1,FAT1,FZD4,GDF11,GLI3,GRHL3,HIF1A,LAMA1,LRP5,MYH10,NAGLU,NHS,PTPRM,SKI,SMARCD3,SMOC1,TENM3,TFAP2A,TGFBR2,TWIST1 |
| GO_ADHERENS_JUNCTION_ORGANIZATION | 1.5e-05 | 2.2e-04 | 1125 | 65 | 9 | CDH12,CDH17,CDH18,CDH7,CDH8,IQSEC1,JUP,MAPRE2,VCL |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 1.5e-05 | 2.3e-04 | 1125 | 1364 | 56 | ACPP,ADCY1,ADCY9,ADORA1,ADRB1,ADRB2,AGRN,ARHGEF19,ARHGEF26,ARHGEF4,ARRB1,ARRB2,BDKRB2,CELSR2,CHRM3,ESR1,F2RL2,FZD1,FZD3,FZD4,GLRB,GNB5,GNG12,GNRHR2,GPR153,GPR157,HTR1D,IQGAP2,LGR4,LPAR1,LTB4R,MCF2,MRAP2,NXPH3,OR1D2,OR2B6,OR2W3,OR4F17,OR52N1,PDE3B,PICK1,PLCB2,PPEF1,PPP1R9B,PRKCA,RAPGEF4,RGS19,ROCK2,SLC9A3R1,SNCA,SORCS2,SORT1,TIAM1,TMOD2,UCN,VAV3 |
| GO_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 1.5e-05 | 2.2e-04 | 1125 | 201 | 16 | CDC42EP3,EVL,ID1,IQGAP2,ITGB1BP1,LIMK1,LPAR1,NIN,PICK1,PPM1E,PTK2B,RGCC,ROCK2,SEMA5A,SPIRE2,WNT11 |
| GO_RECEPTOR_MEDIATED_ENDOCYTOSIS | 1.5e-05 | 2.3e-04 | 1125 | 320 | 21 | ADRB2,AP2A2,ARRB1,ARRB2,CD9,DLG4,DNAJC6,DNM3,EFNB2,HIP1,IGHV4-34,LDLRAD3,LDLRAP1,LRP3,PICK1,SCARB1,SNCA,SNX1,SORL1,TGFBR2,TNK2 |
| GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 1.5e-05 | 2.3e-04 | 1125 | 346 | 22 | ADRB2,ANK3,ATP7A,ATPSCKMT,DLG3,DLG4,FGF12,GNB5,GPD1L,HSPA2,LRRC7,MINK1,PRKACA,PTK2B,RNF207,SCN1B,SLC9A3R1,SNCA,STIM2,TWIST1,WWP2,YWHAH |
| GO_STEROID_BIOSYNTHETIC_PROCESS | 1.5e-05 | 2.2e-04 | 1125 | 201 | 16 | AMACR,CLCN2,CYP2R1,ELOVL6,ERLIN2,HINT2,HSD17B8,IGFBP7,NR1H4,PBX1,PLPP6,PMVK,SCAP,SCARB1,SREBF1,TM7SF2 |
| GO_EXOCYTIC_PROCESS | 1.6e-05 | 2.4e-04 | 1125 | 82 | 10 | P2RX1,PPFIA3,RAB3A,RAB3D,SEPTIN5,SNAP47,SNCA,STXBP1,UNC13B,VPS18 |
| GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | 1.6e-05 | 2.4e-04 | 1125 | 82 | 10 | ARPP19,DGAT2,FOXO1,GPLD1,HIF1A,IRS1,PFKFB2,PPARA,SLC25A12,SNCA |
| GO_PROTEIN_MANNOSYLATION | 1.6e-05 | 2.4e-04 | 1125 | 25 | 6 | B4GAT1,CRPPA,DPY19L1,DPY19L3,TMTC2,TMTC3 |
| GO_CAMERA_TYPE_EYE_MORPHOGENESIS | 1.7e-05 | 2.5e-04 | 1125 | 119 | 12 | CDON,FAT1,GDF11,GLI3,HIF1A,LRP5,NAGLU,PTPRM,SKI,TENM3,TFAP2A,TWIST1 |
| GO_CELL_MATRIX_ADHESION | 1.7e-05 | 2.5e-04 | 1125 | 226 | 17 | BCR,DISC1,DUSP22,FN1,ITGA3,ITGB1BP1,JUP,KDR,LAMA5,MINK1,PECAM1,PTK2B,ROCK2,TAOK2,TIAM1,TMEM8B,VCL |
| GO_COGNITION | 1.7e-05 | 2.5e-04 | 1125 | 298 | 20 | ADCY1,ADORA1,BCHE,C1QL1,CRTC1,DGCR2,DLG4,DOP1B,GM2A,GPR155,HIF1A,ITGA3,NPTN,PPP1R9B,RAG1,SGK1,SLC12A5,TANC1,TMOD2,UCN |
| GO_FATTY_ACID_BIOSYNTHETIC_PROCESS | 1.7e-05 | 2.5e-04 | 1125 | 160 | 14 | ABCD2,ABCD3,ACSM2B,ADIPOQ,ASAH2,ELOVL6,ERLIN2,FADS3,HSD17B8,LPL,MECR,MLYCD,PTGS1,SCAP |
| GO_FIBROBLAST_GROWTH_FACTOR_PRODUCTION | 1.7e-05 | 2.5e-04 | 1125 | 8 | 4 | HEG1,RGCC,ROCK2,WNT11 |
| GO_MESONEPHRIC_TUBULE_MORPHOGENESIS | 1.7e-05 | 2.5e-04 | 1125 | 66 | 9 | CITED1,CTNNBIP1,FAT4,GLI3,LAMA5,LGR4,PBX1,PTCH1,WNT11 |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 1.7e-05 | 2.5e-04 | 1125 | 1016 | 45 | ADAM10,ARMC2,ATP8B3,BBS2,C11orf74,CD9,CFAP44,CXADR,ESR1,FSTL3,GJA1,GLRB,HSPA2,IFT81,IGFBP7,IMMP2L,ITGA3,JAG2,LGR4,MARF1,MEIG1,MEN1,OR1D2,P2RX1,PAPPA,PAQR8,PICK1,PPP1R9B,PRKACA,PTK2B,RAB3A,RECK,SPIRE2,STK11,STXBP1,SUN1,TCFL5,TGFBR2,TTLL1,TXNRD3,UCN,UNC13B,VGF,ZFP41,ZP3 |
| GO_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 1.7e-05 | 2.5e-04 | 1125 | 51 | 8 | CITED1,ID1,LRP5,MEN1,PTCH1,SKI,SMAD6,TWIST1 |
| GO_POSITIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY | 1.7e-05 | 2.5e-04 | 1125 | 51 | 8 | EVL,ITGB1BP1,LIMK1,LPAR1,PPM1E,RGCC,ROCK2,WNT11 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 1.7e-05 | 2.5e-04 | 1125 | 1670 | 65 | ADAM10,ADIPOQ,ADORA1,AGO1,APPL1,ARRB2,ASH2L,BCR,CD200,CD9,CFI,CTNNBIP1,CXADR,DUSP22,EFNB2,ESR1,FOXP1,FSTL3,GAS6,GLI2,GLI3,GPLD1,H3C10,H3C12,H4C9,HIF1A,HTRA1,IFNAR2,IGHV4-34,IL18,IRF4,KLRC4-KLRK1,KLRD1,LGR4,LILRB3,LIMK1,LMO2,MUC2,NR1H4,PRKACA,PRKCA,PRKCH,PTK2B,PURB,RAB7B,RAG1,RGCC,SARM1,SERPING1,SNCA,SOX13,STAT1,STK11,STXBP1,TGFBR2,TNFSF14,TNRC6C,TRIM44,TRIM58,TRIM6,TSPAN6,UNC93B1,VAV3,VSIR,ZP3 |
| GO_SPHINGOLIPID_METABOLIC_PROCESS | 1.7e-05 | 2.5e-04 | 1125 | 160 | 14 | ALDH3A2,ALDH5A1,ASAH2,B3GALT1,CPTP,ELOVL6,GBA2,GM2A,P2RX1,SGMS1,SIRT3,SPTLC3,ST6GALNAC3,TEX2 |
| GO_PHOSPHATIDYLCHOLINE_METABOLIC_PROCESS | 1.8e-05 | 2.6e-04 | 1125 | 83 | 10 | CDS1,CHKA,GPLD1,LPCAT3,LPCAT4,PCTP,PLA2G12A,PLAAT3,SCARB1,SLC44A1 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 1.8e-05 | 2.6e-04 | 1125 | 624 | 32 | ADCK1,ADRB2,ARRB1,ATF7IP,C6orf89,CDC42EP3,CROCC,EVL,FYCO1,HIF1A,ID1,IQGAP2,ITGB1BP1,JARID2,KDR,LIG4,LIMK1,LMNA,LPAR1,LRP5,NIN,PICK1,PPM1E,PTK2B,RGCC,ROCK2,SEMA5A,SLX4,SPIRE2,SREBF1,WNT11,YWHAH |
| GO_REGULATION_OF_PEPTIDASE_ACTIVITY | 1.8e-05 | 2.6e-04 | 1125 | 455 | 26 | ANTXR1,ARRB1,ARRB2,CASP9,COL28A1,CRADD,EPHA7,FN1,GAS6,HIP1,MAP3K5,NLRP1,NLRP2,P2RX1,RAG1,RECK,ROCK2,SERPINB13,SERPING1,SERPINI1,SNCA,SORL1,SPINT2,SPOCK1,TNFSF14,VSIR |
| GO_REGULATION_OF_PH | 1.8e-05 | 2.6e-04 | 1125 | 101 | 11 | ATP6AP1L,ATP6V0A1,ATP6V0E2,ATP6V1E2,ATP6V1G2,CLN5,DMXL2,SLC4A4,SLC9A6,SLC9A7,TMEM175 |
| GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 1.9e-05 | 2.8e-04 | 1125 | 252 | 18 | ADIPOQ,AGO1,ASH2L,CTNNBIP1,FOXP1,FSTL3,H3C10,H3C12,H4C9,HIF1A,LILRB3,PRKCA,PTK2B,PURB,RAB7B,STAT1,TNRC6C,TRIM58 |
| GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 1.9e-05 | 2.8e-04 | 1125 | 351 | 22 | ARHGAP28,ASAP3,CAPZA2,CDC42EP3,EVL,GBA2,ID1,IQGAP2,ITGB1BP1,LIMK1,LPAR1,NIN,PICK1,PPM1E,PTK2B,RGCC,ROCK2,SEMA5A,SNCA,SPIRE2,TMOD2,WNT11 |
| GO_ACYLGLYCEROL_HOMEOSTASIS | 2.0e-05 | 2.9e-04 | 1125 | 38 | 7 | ADORA1,DGAT2,FITM2,IL18,LPL,NR1H4,SCARB1 |
| GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | 2.0e-05 | 2.9e-04 | 1125 | 184 | 15 | ATP7A,BCL11B,DISC1,ERBB4,FZD1,GBA2,GDPD5,GLI2,GLI3,HERC1,NIN,PTCH1,ROBO2,SCN1B,SPOCK1 |
| GO_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | 2.0e-05 | 2.9e-04 | 1125 | 52 | 8 | FSTL3,FZD1,HTRA1,SKI,SKOR1,SMAD6,SORL1,SOST |
| GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | 2.0e-05 | 2.9e-04 | 1125 | 277 | 19 | ADORA1,ADRB2,ANK3,ARRB2,ATPSCKMT,FGF12,GPD1L,HSPA2,P2RX1,PKP2,RNF207,SCN1B,SLC9A3R1,SNCA,STIM2,STXBP1,TCAF1,TNFRSF11A,UCN |
| GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS | 2.0e-05 | 2.9e-04 | 1125 | 352 | 22 | AASDH,ADCY1,ALDH5A1,ALDH7A1,ATP7A,BCHE,CHKA,DDAH1,KLRC4-KLRK1,MAOB,P2RX1,PPFIA3,PTK2B,RAB3A,ROCK2,SEPTIN5,SLC44A1,SNAP47,SNCA,STXBP1,UNC13B,VPS18 |
| GO_RENAL_ABSORPTION | 2.0e-05 | 2.9e-04 | 1125 | 16 | 5 | ADIPOQ,GAS6,HYAL2,SGK1,SLC9A3R1 |
| GO_ANATOMICAL_STRUCTURE_MATURATION | 2.1e-05 | 3.0e-04 | 1125 | 163 | 14 | AGRN,ANKS1A,C1QL1,CLN5,ERCC2,FAM20C,FAT4,HIF1A,MAP3K13,PICK1,PTK2B,RECK,RFLNB,TRIM58 |
| GO_AXON_EXTENSION | 2.1e-05 | 3.0e-04 | 1125 | 122 | 12 | DISC1,FN1,LIMK1,MAP3K13,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A6,VCL |
| GO_CIRCADIAN_RHYTHM | 2.1e-05 | 3.0e-04 | 1125 | 207 | 16 | ADCY1,ADIPOQ,ADORA1,CRTC1,DBP,GPR157,ID1,KLF9,LGR4,NAGLU,PPARA,ROCK2,SREBF1,THRAP3,TNFRSF11A,USP2 |
| GO_CYTOKINE_PRODUCTION | 2.1e-05 | 3.0e-04 | 1125 | 808 | 38 | ABCD2,ADIPOQ,APPL1,ARRB1,ARRB2,C1QTNF4,CD200,CPTP,FN1,FOXP1,GAS6,HEG1,HIF1A,HYAL2,IL18,IRF4,KLRC4-KLRK1,LGR4,LPL,NLRP1,NLRP2,NPTN,NR1H4,RAB7B,RGCC,ROCK2,SORL1,STAT1,SULF1,TRIM6,TSPAN6,TWIST1,UBE2L6,UCN,VSIR,WNT11,ZNF287,ZP3 |
| GO_NEGATIVE_REGULATION_OF_AXONOGENESIS | 2.1e-05 | 3.0e-04 | 1125 | 68 | 9 | EPHA7,MCF2,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TRAK2 |
| GO_REGULATION_OF_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 2.1e-05 | 3.0e-04 | 1125 | 142 | 13 | ADIPOQ,ARPP19,DGAT2,ENPP1,FOXO1,GPLD1,IRS1,MLYCD,PFKFB2,PPARA,PTK2B,SLC25A12,SNCA |
| GO_REGULATION_OF_PEPTIDE_HORMONE_SECRETION | 2.1e-05 | 3.0e-04 | 1125 | 207 | 16 | ARRB1,GJA1,GPLD1,HIF1A,IRS1,LRP5,NR1H4,PFKFB2,PRKCA,RAPGEF4,SIRT3,SREBF1,STXBP4,TIAM1,TM7SF3,UCN |
| GO_REGIONALIZATION | 2.2e-05 | 3.1e-04 | 1125 | 354 | 22 | BASP1,CDON,CELSR2,CTNNBIP1,CXXC4,GDF11,GLI2,GLI3,HOXD8,IRX2,LFNG,LRP5,PBX1,POGLUT1,PRKACA,PTCH1,ROBO2,SEMA3F,SKI,SMAD6,SMARCD3,SSBP3 |
| GO_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS | 2.2e-05 | 3.1e-04 | 1125 | 103 | 11 | ADIPOQ,AP2A2,DGAT2,GPLD1,LDLRAP1,LPCAT3,LPL,NR1H4,PRKACA,SCARB1,ZDHHC8 |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 2.3e-05 | 3.3e-04 | 1125 | 518 | 28 | ADIPOQ,ADORA1,ADRB2,ARRB1,CCNJL,CCNYL1,FZD4,HEG1,HYAL2,INKA2,LPAR1,LRP5,MAP3K13,MAP3K5,MAP4K2,MEN1,PKIA,PTK2B,RGCC,SHC2,SNCA,SORL1,SPRY3,STK38,TAOK2,TIAM1,TNFRSF11A,TPD52L1 |
| GO_REGULATION_OF_TUBE_SIZE | 2.3e-05 | 3.2e-04 | 1125 | 143 | 13 | ADORA1,ADRB1,ADRB2,BBS2,BDKRB2,CHRM3,GJA1,HTR1D,ITGB1BP1,P2RX1,PTPRM,ROCK2,UCN |
| GO_NEURAL_CREST_CELL_DIFFERENTIATION | 2.4e-05 | 3.4e-04 | 1125 | 86 | 10 | ERBB4,FN1,HIF1A,LAMA5,NRTN,SEMA3F,SEMA4F,SEMA4G,SEMA6D,TWIST1 |
| GO_FOREBRAIN_DEVELOPMENT | 2.5e-05 | 3.4e-04 | 1125 | 383 | 23 | ATP7A,BBS2,BCL11B,CDON,DISC1,DIXDC1,ERBB4,FAT4,GDPD5,GLI2,GLI3,GNG12,HIF1A,LPAR1,MYH10,NIN,PPP1R9B,ROBO2,RTN4R,SEMA5A,SKI,SUN1,TRAPPC9 |
| GO_GLUCOSE_METABOLIC_PROCESS | 2.5e-05 | 3.5e-04 | 1125 | 210 | 16 | ADIPOQ,ALDH5A1,ARPP19,BRAT1,DGAT2,ENPP1,FOXO1,GDPGP1,GPLD1,H6PD,IRS1,LRP5,MLYCD,PFKFB2,PPARA,SLC25A12 |
| GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | 2.5e-05 | 3.4e-04 | 1125 | 144 | 13 | ADORA1,ADRB1,ADRB2,ARRB2,CHRNA9,CHRNE,DLG4,GLRB,MPP2,P2RX1,PTK2B,SNCA,UNC13B |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 2.6e-05 | 3.7e-04 | 1125 | 188 | 15 | ADAM10,AGR2,ANK3,APPL1,GOPC,ITGA3,ITGB1BP1,LDLRAP1,MRAP2,MTCL1,PPP1R9B,PPP2R5A,PRKCH,TCAF1,YWHAH |
| GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 2.7e-05 | 3.7e-04 | 1125 | 258 | 18 | ADIPOQ,CAMK2N2,DUSP22,HEG1,HYAL2,INKA2,ITGB1BP1,LRP5,MEN1,MVP,PKIA,PPM1E,PPP2R5A,SMYD3,SORL1,SPRY3,STK38,ZFYVE28 |
| GO_CARBOHYDRATE_DERIVATIVE_CATABOLIC_PROCESS | 2.8e-05 | 3.9e-04 | 1125 | 189 | 15 | AGRN,CEMIP2,GBA2,GM2A,GPD1L,HYAL2,MLYCD,NAGLU,NT5M,NUDT11,NUDT16,NUDT18,NUDT7,SDC3,TYMP |
| GO_COENZYME_BIOSYNTHETIC_PROCESS | 2.8e-05 | 3.9e-04 | 1125 | 146 | 13 | COQ8B,DHFR2,ELOVL6,GPHN,HSD17B8,IDH2,MAT2A,MAT2B,MLYCD,MOCS1,MOCS3,MPC1,SNCA |
| GO_HEART_MORPHOGENESIS | 2.8e-05 | 3.9e-04 | 1125 | 259 | 18 | FAT4,FGFRL1,FZD1,HEG1,HIF1A,PKP2,PLXND1,PTCD2,PTCH1,RNF207,ROBO2,SMAD6,SMARCD3,SOX18,TGFBR2,TWIST1,WNT11,XIRP2 |
| GO_ACROSOMAL_VESICLE_EXOCYTOSIS | 2.9e-05 | 4.0e-04 | 1125 | 9 | 4 | RAB3A,STXBP1,UNC13B,ZP3 |
| GO_CHOLINE_METABOLIC_PROCESS | 2.9e-05 | 4.0e-04 | 1125 | 9 | 4 | ALDH7A1,BCHE,CHKA,SLC44A1 |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 2.9e-05 | 4.0e-04 | 1125 | 553 | 29 | ARMC2,BBS2,CCDC68,CDC14B,CEP68,CFAP44,CROCC,DISC1,DIXDC1,GAS2L1,GBA2,GJA1,KATNAL2,KIF3A,LLGL1,LLGL2,LMNA,MAP10,MAPRE2,MTCL1,NIN,PARD6A,ROCK2,SNCA,SPIRE2,STMN3,SUN1,TTLL1,TUBG2 |
| GO_RESPONSE_TO_RADIATION | 2.9e-05 | 4.0e-04 | 1125 | 441 | 25 | ACTR5,ARRB1,BRAT1,CASP9,CDS1,CRTC1,CYP2R1,ERCC2,ERCC4,H2AW,HIF1A,HYAL2,LIG4,MEN1,NPTN,NSMCE3,PPEF1,RAG1,REEP6,SERPINB13,SPIDR,STK11,TANC1,TNFRSF11A,USP2 |
| GO_NEURON_PROJECTION_EXTENSION | 3.0e-05 | 4.1e-04 | 1125 | 168 | 14 | DISC1,FN1,LIMK1,MAP3K13,RTN4R,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,SLC9A6,STK11,TIAM1,VCL |
| GO_STEROL_METABOLIC_PROCESS | 3.0e-05 | 4.1e-04 | 1125 | 168 | 14 | CYP4V2,DGAT2,ELOVL6,ERLIN2,GBA2,LDLRAP1,LIPE,NR1H4,PLPP6,PMVK,SCAP,SCARB1,SREBF1,TM7SF2 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 3.1e-05 | 4.2e-04 | 1125 | 362 | 22 | ANKIB1,ANTXR1,ARRB1,CASP9,CRADD,DISC1,FBXW8,FN1,GPLD1,HIP1,MAGEF1,MAP3K5,NLRP1,NLRP2,P2RX1,PRICKLE1,PTK2B,RNFT1,ROCK2,SNCA,TMTC3,VSIR |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 3.1e-05 | 4.2e-04 | 1125 | 1567 | 61 | ADIPOQ,APPL1,ARRB2,ATG10,ATP7A,BCR,CAPZA2,CASP9,CFI,CITED1,ESR1,EVL,FBH1,FOXP1,GJA1,GNG12,H2BC4,HTRA1,HYAL2,IFI30,IFNAR2,IGHV4-34,IL18,IRF4,KLRC2,KLRC4-KLRK1,KLRD1,LGR4,LOXL1,LPL,MAOB,MAP3K5,MAP4K2,MUC2,NAALADL2,NLRP1,NLRP2,NR1H4,PLAAT3,PRKACA,PRKCA,RAB7B,SARM1,SCARB1,SERPING1,SGMS1,SLX4,SMAD6,SNCA,SRR,STAT1,STXBP1,STXBP4,TNFRSF11A,TRIM34,TRIM44,TRIM6,TSPAN6,UNC13B,UNC93B1,VGF |
| GO_RESPONSE_TO_LIGHT_STIMULUS | 3.1e-05 | 4.3e-04 | 1125 | 311 | 20 | ACTR5,ARRB1,CASP9,CDS1,CRTC1,ERCC2,ERCC4,H2AW,HIF1A,HYAL2,MEN1,NPTN,NSMCE3,PPEF1,RAG1,REEP6,SERPINB13,STK11,TANC1,USP2 |
| GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 3.2e-05 | 4.3e-04 | 1125 | 286 | 19 | ADIPOQ,CAMK2N2,DUSP22,HEG1,HYAL2,INKA2,ITGB1BP1,LIMK1,LRP5,MEN1,MVP,PKIA,PPM1E,PPP2R5A,SMYD3,SORL1,SPRY3,STK38,ZFYVE28 |
| GO_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | 3.2e-05 | 4.3e-04 | 1125 | 214 | 16 | ACTBL2,ADCY1,DNAJC6,DNM3,EFNB2,P2RX1,PCDH17,PPFIA3,RAB3A,RAPGEF4,SEPTIN5,SNAP47,SNCA,STXBP1,UNC13B,VPS18 |
| GO_MAINTENANCE_OF_LOCATION | 3.3e-05 | 4.5e-04 | 1125 | 338 | 21 | ANK3,ATP7B,DGAT2,ENPP1,FITM2,GM2A,GOPC,JUP,LPL,PLCB2,PLCD3,PPARA,PRKACA,PTK2B,SCARB1,SLC25A23,SLC30A4,SNCA,SORL1,SUN1,TPCN1 |
| GO_POSITIVE_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS | 3.3e-05 | 4.5e-04 | 1125 | 41 | 7 | ARPP19,DGAT2,FOXO1,GPLD1,IRS1,PPARA,SLC25A12 |
| GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | 3.3e-05 | 4.5e-04 | 1125 | 41 | 7 | CITED1,DISC1,FZD3,GJA1,GLI3,HIF1A,SMARCD3 |
| GO_CARBOHYDRATE_DERIVATIVE_TRANSPORT | 3.4e-05 | 4.6e-04 | 1125 | 72 | 9 | ADORA1,AGR2,GJA1,SCARB1,SLC25A23,SLC25A42,SLC35A1,SLC35A5,SLC35C1 |
| GO_NEGATIVE_REGULATION_OF_BINDING | 3.4e-05 | 4.6e-04 | 1125 | 170 | 14 | ADIPOQ,ADRB2,ARHGAP28,ARRB2,CTNNBIP1,DISC1,ERCC4,FBH1,GPSM1,HABP4,ID1,ITGB1BP1,PPARA,SORL1 |
| GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | 3.5e-05 | 4.7e-04 | 1125 | 56 | 8 | FGF12,GJA1,GJC1,GPD1L,JUP,PKP2,RNF207,SCN1B |
| GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | 3.5e-05 | 4.7e-04 | 1125 | 56 | 8 | CXADR,GJA1,GJC1,JUP,PKP2,PRKACA,RNF207,SCN1B |
| GO_CELLULAR_COMPONENT_MAINTENANCE | 3.5e-05 | 4.7e-04 | 1125 | 56 | 8 | C1QL1,DLG3,ITGA3,MTHFR,PARD6A,PICK1,RAB3A,TANC1 |
| GO_RECEPTOR_LOCALIZATION_TO_SYNAPSE | 3.5e-05 | 4.7e-04 | 1125 | 56 | 8 | ADAM10,DLG3,DLG4,GPHN,LRRC7,NPTN,SNAP47,SYNJ2BP |
| GO_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 3.5e-05 | 4.7e-04 | 1125 | 149 | 13 | CDON,CLCN2,COL4A1,FZD4,HIF1A,LAMA1,LRP5,MYH10,NAGLU,PTPRM,SKI,SMARCD3,TFAP2A |
| GO_REGULATION_OF_CHEMOTAXIS | 3.6e-05 | 4.7e-04 | 1125 | 216 | 16 | ADAM10,EFNB2,GAS6,KDR,KLRC4-KLRK1,LPAR1,PTK2B,ROBO2,SEMA3F,SEMA4F,SEMA4G,SEMA5A,SEMA6D,TIAM1,TNFSF14,ZSWIM5 |
| GO_RESPONSE_TO_CYTOKINE | 3.6e-05 | 4.8e-04 | 1125 | 1210 | 50 | ADAM10,ADIPOQ,APPL1,ASAH2,BBS2,C1QTNF4,CITED1,EVL,FN1,FOXO1,FZD4,GAS6,H3C10,H3C12,HIF1A,HYAL2,IFI30,IFNAR2,IL11RA,IL18,IRF4,IRS1,JARID2,LAMA5,LDLRAP1,LIFR,MAP3K5,MAT2A,MCF2,MPC1,MTHFR,NR1H4,PRKACA,PRKCA,PTK2B,PTPN13,PTPN14,RAB7B,SGMS1,SNCA,SNX10,STAT1,STXBP1,STXBP4,TNFRSF11A,TNFSF14,TRIM34,TRIM44,TRIM6,TWIST1 |
Num: 3 (Pathways: 261 DK: 8)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (8) | ADCK2, CAMKK2, CDK13, CSNK1G2, MAST4, NEK6, SCYL3, TP53RK |
| Light Kinase (16) | ALPK1, CLK2, EGFR, MTOR, NLK, PDGFRA, PDK4, PIK3CG, PKN1, PKN2, ROR1, RYK, STK24, STK39, TBRG4, TEK |
| Non-kinase Count | 876 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1859 | 136 | AASDHPPT,ABHD17C,ACSL4,ACSL5,ADCY7,ADSL,AGK,AGMAT,AIMP2,ALG2,ALG3,APEH,APIP,ASAH2B,ASL,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,B4GALT2,B4GALT7,BCL3,CBS,CBSL,CHPT1,CNDP2,CSNK1G2,DHPS,DPAGT1,DPH6,EGFR,EGR1,EIF2B5,EIF4E2,ESD,EXTL3,FARSA,GALNT15,GCDH,GCH1,GCNT1,GGT5,GHRL,GSS,HAGH,HAS2,HMBS,IMPACT,IMPDH2,JMJD4,KRTCAP2,LCMT2,LPCAT1,LSM14A,LSM14B,MCTS1,MGAT1,MGAT2,MIF4GD,MPI,MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,MTOR,MUC1,NADK2,NAT8L,NCBP2,NDUFA7,NNMT,OST4,PANK4,PARK7,PARP10,PCBD2,PDF,PDK4,PEMT,PIGC,PIGO,PIGV,POLR2G,PORCN,PPA1,PPA2,PRKAG2,PUDP,PYCR2,PYCR3,PYURF,QDPR,RFK,RNF139,RPL26L1,RPL36AL,RPUSD3,RSAD1,SECISBP2,SEPHS2,SGMS2,SLC25A15,SMPD2,SPHK2,SPTSSB,TAMM41,TLR3,TMA7,TMEM14C,TRMT112,TRMT12,TSPO,UCK2,UQCC3,VARS1,YARS2,ZDHHC4,ZNF598,ZNF706 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1962 | 133 | AASDHPPT,ABCG1,ACOXL,ACSL4,ACSL5,ADCY7,ADSL,AGMAT,AHCY,AIMP2,ALDH1A1,ALDH1A3,APIP,ARV1,ASAH2B,ASL,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,AWAT2,B4GALT2,C1QTNF1,C1QTNF12,CAV1,CBS,CBSL,CES1,CLK2,CLYBL,CMAS,COQ3,COQ7,CYP19A1,CYP1B1,CYP2D6,CYP4A11,DNPH1,DPAGT1,EGR1,ESD,FAAH2,FAM3A,FARSA,FH,FUOM,G6PC3,GALE,GCAT,GCDH,GCH1,GDA,GGT5,GHRL,GNPAT,GRHPR,GSS,GUSB,HAGH,HAS2,HIBADH,HPDL,IDUA,IGFBP4,IMPDH2,INPP1,ISCU,KYAT3,LONP2,LYPLA1,MACROD1,MDH2,MGAT1,MGLL,MMUT,MPI,MTOR,NADK2,NANP,NAPEPLD,NAT8L,NIT2,NNMT,NUP37,OARD1,OXCT1,PANK4,PARK7,PARP10,PCBD2,PCK2,PDK4,PDZD11,PEMT,PGP,PHYKPL,PNPLA4,PPA1,PPA2,PPM1K,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,PTGES2,PUDP,PYCR2,PYCR3,QDPR,RDH5,RFK,SCLY,SDSL,SEH1L,SEPHS2,SLC25A15,SLC27A3,SLC27A5,SLC37A4,SNX17,SPHK2,TAMM41,TFAP2B,TYSND1,UCK2,UQCC3,VARS1,XDH,YARS2,ZADH2 |
| GO_AMIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 876 | 70 | ACSL4,ACSL5,AGK,AIMP2,APEH,ASL,ATIC,BCL3,CNDP2,DHPS,DPH6,EGFR,EIF2B5,EIF4E2,FARSA,GCDH,GCH1,GGT5,GSS,HAGH,IMPACT,JMJD4,LSM14A,LSM14B,MCTS1,MIF4GD,MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,MTOR,NCBP2,NDUFA7,PDF,PDK4,PEMT,POLR2G,PPA1,PPA2,RNF139,RPL26L1,RPL36AL,RPUSD3,SECISBP2,SGMS2,SLC25A15,SMPD2,SPHK2,SPTSSB,TMA7,TRMT112,VARS1,YARS2,ZNF598,ZNF706 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1146 | 80 | AASDHPPT,ABCG1,ACSL4,ACSL5,AGK,AIMP2,APEH,ASAH2B,ASL,ATIC,BCL3,CES1,CNDP2,DHPS,DPH6,EGFR,EIF2B5,EIF4E2,FARSA,GCDH,GCH1,GGT5,GSS,HAGH,IMPACT,JMJD4,LSM14A,LSM14B,MCTS1,MIF4GD,MIPEP,MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,MTOR,NAPEPLD,NCBP2,NDUFA7,NIT2,PARK7,PDF,PDK4,PDZD11,PEMT,POLR2G,PPA1,PPA2,RNF139,RPL26L1,RPL36AL,RPUSD3,SCG5,SECISBP2,SGMS2,SLC25A15,SMPD2,SPHK2,SPTSSB,TMA7,TRMT112,VARS1,YARS2,ZNF598,ZNF706 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1164 | 77 | AASDHPPT,ACOXL,ACSL4,ACSL5,AGMAT,AHCY,AIMP2,ALDH1A3,APIP,ARV1,ASAH2B,ASL,ATIC,B4GALT2,CAV1,CBS,CBSL,CES1,CMAS,CYP1B1,CYP2D6,CYP4A11,FAAH2,FARSA,FH,GCAT,GCDH,GCH1,GGT5,GNPAT,GRHPR,GSS,GUSB,HAGH,HAS2,HIBADH,HPDL,IDUA,KYAT3,LONP2,LYPLA1,MDH2,MGLL,MMUT,MTOR,NANP,NAT8L,NIT2,NUP37,PARK7,PCK2,PDK4,PDZD11,PEMT,PHYKPL,PPA1,PPA2,PPM1K,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,PTGES2,PYCR2,PYCR3,QDPR,SCLY,SDSL,SEH1L,SEPHS2,SLC27A3,SLC27A5,TYSND1,VARS1,YARS2,ZADH2 |
| GO_PEPTIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 736 | 56 | AIMP2,APEH,BCL3,CNDP2,DHPS,DPH6,EGFR,EIF2B5,EIF4E2,FARSA,GGT5,GSS,HAGH,IMPACT,JMJD4,LSM14A,LSM14B,MCTS1,MIF4GD,MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,MTOR,NCBP2,NDUFA7,PDF,POLR2G,PPA1,PPA2,RNF139,RPL26L1,RPL36AL,RPUSD3,SECISBP2,TMA7,TRMT112,VARS1,YARS2,ZNF598,ZNF706 |
| GO_PEPTIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 879 | 61 | ABCG1,AIMP2,APEH,BCL3,CES1,CNDP2,DHPS,DPH6,EGFR,EIF2B5,EIF4E2,FARSA,GGT5,GSS,HAGH,IMPACT,JMJD4,LSM14A,LSM14B,MCTS1,MIF4GD,MIPEP,MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,MTOR,NCBP2,NDUFA7,PARK7,PDF,POLR2G,PPA1,PPA2,RNF139,RPL26L1,RPL36AL,RPUSD3,SCG5,SECISBP2,TMA7,TRMT112,VARS1,YARS2,ZNF598,ZNF706 |
| GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 337 | 37 | AASDHPPT,AGMAT,AHCY,AIMP2,APIP,ASL,CBS,CBSL,FARSA,GCAT,GCDH,GGT5,GSS,HIBADH,HPDL,KYAT3,MMUT,NAT8L,NIT2,PARK7,PEMT,PHYKPL,PPA1,PPA2,PPM1K,PSMB10,PSMB8,PSMB9,PSMD10,PYCR2,PYCR3,QDPR,SCLY,SDSL,SEPHS2,VARS1,YARS2 |
| GO_DRUG_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 600 | 48 | ADSL,AHCY,ALDH1A1,APIP,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CAV1,CBS,CBSL,CHPT1,CLYBL,CMAS,COLQ,CYP1B1,CYP2D6,EGFR,EGR1,ESD,GCAT,GCH1,GGT5,HBA2,IDUA,MMUT,MTOR,NANP,OXCT1,PARK7,PCBD2,PCK2,PDZD11,PEMT,PRKAG2,PYCR2,PYCR3,QDPR,RAC2,RFK,RNF34,SDSL,SLC27A5,SPHK2,SQOR,TSPO,UQCC3 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1005 | 63 | ACOXL,ADSL,AIFM1,ALDH1A1,ALDH1A3,ALKBH2,CBS,COQ7,COX8A,CYP19A1,CYP1B1,CYP2D6,CYP3A43,CYP4A11,DUS1L,ENOX2,FH,FOXRED1,GCDH,GRHPR,GYG1,HIBADH,HPDL,IMPDH2,ISCU,JMJD4,LONP2,MDH2,MICAL2,MTOR,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,PCBD2,PDK4,PRKAG2,PTGES2,PYCR2,PYCR3,QDPR,RDH5,RIOX2,RSAD1,SCCPDH,SDHAF4,SH3BGRL3,SLC25A22,SLC27A5,SQOR,STEAP1,STEAP2,STEAP4,TXNDC12,TXNDC17,TYSND1,UQCC3,UQCRFS1,VCAM1,XDH,ZADH2 |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1064 | 65 | ABCG1,ACOXL,ACSL4,ACSL5,AGK,ALDH1A1,ALDH1A3,ALG2,ALG3,ARV1,ASAH2B,AWAT2,CAV1,CCDC71L,CES1,CHPT1,CRLS1,CSNK1G2,CYP1B1,CYP2D6,CYP4A11,DPAGT1,EGFR,FAAH2,GCDH,GGT5,GNPAT,INPP1,LONP2,LPCAT1,LRP8,LYPLA1,MGLL,MMUT,MTOR,NAPEPLD,PCK2,PDGFRA,PDK4,PEMT,PGP,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PNPLA4,PRKAG2,PTGES2,PTPMT1,PYURF,RDH5,SCCPDH,SGMS2,SLC27A3,SLC27A5,SMPD2,SPHK2,SPTSSB,SUMF2,TAMM41,TEK,TYSND1,ZADH2 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 900 | 1782 | 88 | ADSL,AIMP2,ALDH1A3,ANKRA2,ANKRD28,APCS,APIP,ARF6,BIRC3,BRK1,CBY1,CDC42EP1,CLDN1,CLYBL,COA4,COPS7A,COX14,COX17,DDB2,DNAAF2,DNAH5,DPAGT1,EPS8,ERCC1,FARSA,FIS1,FOXRED1,GBP1,GCH1,GEMIN7,GRHPR,GRIA1,GSDMD,H1-10,H3-3B,H4C11,IMPACT,IMPDH2,KCNG2,KIF9,KLHL12,KRT10,LRRC6,MCTS1,MEFV,MKKS,MLST8,MRPL20,MRPS11,MTLN,MTOR,NDUFA7,NDUFAF8,NDUFB6,NDUFS1,NDUFV1,NDUFV3,NFE4,PARK7,PDZD11,PET117,PSMD10,PSMG4,RANGRF,RASA1,RASIP1,RUVBL1,SCO1,SDHAF1,SDHAF4,SERPINA1,SIGMAR1,SMAD1,SMIM20,SNAP29,STEAP4,TAF9,TEK,TRAPPC11,TRAPPC4,TRIM27,TRPS1,TSPAN4,TYSND1,UQCC3,USP4,VAMP2,VAMP4 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 900 | 1559 | 80 | ADCY7,ALPK1,APCS,ARNTL,BABAM2,BAG5,BIRC3,C1QTNF1,C1QTNF12,C2CD4A,CASP1,CAV1,CCN4,CHID1,CLDN1,CYP19A1,EDEM2,EGFR,ELMOD2,EPG5,ERCC1,F12,FAM3A,FBXO4,FMN2,FOXF1,GCH1,GHRL,IFI16,IL1RL1,IL20RB,IMPACT,LRP8,LSM14A,MAD2L2,MAPKAP1,MARCO,MEFV,MGLL,MLST8,MTOR,MUC1,MUL1,NAPEPLD,NEK6,NLRC5,NSMCE1,NSMCE4A,NUP37,PARK7,PDGFRA,PIK3CG,PKN1,PLAU,PRRX1,PSMB10,PSMB8,PSMB9,PSMD10,RAET1E,SAA1,SBNO2,SEH1L,SERPINB3,SERPINB4,SFRP2,SLAMF8,STK24,STK39,TAF9,TEK,TLR3,TRIAP1,TTLL12,TXNDC12,UBAC2,USP19,WDR70,WRNIP1,XDH |
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1405 | 75 | ABCG1,ACOXL,ACSL4,ACSL5,AGK,ALDH1A1,ALDH1A3,ALG2,ALG3,ARV1,ASAH2B,ATP5F1A,AWAT2,CAV1,CCDC71L,CES1,CHPT1,CRLS1,CSNK1G2,CYP19A1,CYP1B1,CYP2D6,CYP3A43,CYP4A11,DPAGT1,EGFR,EGR1,FAAH2,FAM3A,GCDH,GGT5,GNPAT,INPP1,LIPT1,LONP2,LPCAT1,LRP8,LYPLA1,MGLL,MMUT,MTOR,NAPEPLD,NCEH1,PCK2,PDGFRA,PDK4,PEMT,PGP,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PNPLA4,PRKAG2,PTGES2,PTPMT1,PYURF,RDH5,SCCPDH,SGMS2,SLC27A3,SLC27A5,SMPD2,SNX17,SPHK2,SPTSSB,SUMF2,TAMM41,TEK,TPRA1,TSPO,TYSND1,ZADH2 |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 900 | 528 | 42 | ABLIM3,AGK,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CAMKK2,CAMKMT,CHCHD6,COA4,COX14,COX17,DNAJC19,ESRRA,FIS1,FOXRED1,MICOS13,MIPEP,MUL1,NAIF1,NDUFA7,NDUFAF8,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,PARL,PET117,PSMD10,RAC2,RNF41,SCO1,SDHAF1,SDHAF4,SMIM20,STPG1,TRIAP1,TSPO,UBL5,UQCC3 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 900 | 1703 | 81 | ADCY7,APCS,ARNTL,BAG5,BCL3,BDNF,C1QTNF1,C1QTNF12,CALM2,CAMK2N1,CARD16,CAV1,CBY1,CHID1,CYP19A1,DLC1,EGFR,EGR1,ERCC1,F12,FAM3A,FERMT1,FOXF1,GBP1,GHRL,HHIP,IFI16,IGFBP4,IL1RL1,IL20RB,KLHL12,LEMD3,LIF,MAD2L2,MAPKAP1,MEFV,MKKS,MRAP,MTOR,MUC1,MUL1,NEDD4,NLK,NLRC5,NPRL2,NPRL3,NRARP,PARK7,PDGFRA,PLAU,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RASA1,RASIP1,RGS16,RNF34,RYK,SAA1,SERPINB3,SERPINB4,SFRP2,SLAMF8,SPRY1,SRI,STK39,TAF9,TEK,TLR3,TMEM131L,TRIAP1,TRIM27,TTLL12,TXNDC12,UBAC2,WTIP,WWC1,WWC3,XDH |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 723 | 49 | AASDHPPT,ABCG1,ALDH1A3,APIP,ARV1,ASAH2B,ASL,ATIC,C1QTNF12,CBS,CBSL,CES1,CLK2,COQ3,COQ7,CYP19A1,CYP2D6,CYP4A11,DNPH1,EGR1,FAM3A,G6PC3,GCH1,GDA,GGT5,HAS2,IMPDH2,MDH2,MGLL,NANP,NAT8L,PARK7,PCBD2,PCK2,PDK4,PGP,PRKAG2,PTGES2,PUDP,PYCR2,PYCR3,QDPR,RFK,SEPHS2,SLC27A5,SLC37A4,SPHK2,UCK2,XDH |
| GO_TRANSLATIONAL_TERMINATION | 0.0e+00 | 0.0e+00 | 900 | 105 | 20 | APEH,JMJD4,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,TRMT112 |
| GO_MITOCHONDRIAL_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 900 | 165 | 24 | MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,NDUFA7,RPUSD3,TBRG4,TRMT10B,YARS2 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 900 | 1779 | 83 | AGAP3,AIFM1,ANAPC7,APEH,ARNTL,BABAM2,BAG5,BIRC3,CAMK2N1,CARD16,CASP1,CAV1,CES1,CNDP2,COPS6,COPS7A,CSTA,DAP,DCAF11,DDB2,DESI1,DIABLO,DLC1,EDEM2,F12,FBXO39,FBXO4,FIS1,GGT5,IFI16,IFT57,INO80C,LNX1,LONP2,LRP8,MCRS1,MEFV,MIPEP,MMP19,MUL1,MVB12A,NEDD4,OSGEPL1,PARK7,PARL,PCID2,PLAU,PLGRKT,PM20D2,PPM1F,PSMB10,PSMB8,PSMB9,PSMD10,RELN,RHBDD1,RNF139,RNF34,RNF41,RSPRY1,RUVBL1,SCG5,SCO1,SERPINA1,SERPINB3,SERPINB4,SFRP2,SMAD1,SPINK6,SRGN,TAF9,TFAP2B,TMPRSS11B,TRIAP1,TRIM2,TYSND1,UBAC2,USP19,USP20,USP4,USP45,WFDC12,XDH |
| GO_TRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 183 | 25 | AIMP2,C9orf64,DUS1L,ELP3,ELP4,EXOSC7,FARSA,LCMT2,METTL6,OSGEPL1,PPA1,PPA2,RPP38,SEPHS2,THADA,TP53RK,TRMT10B,TRMT112,TRMT12,TRMT6,TRPT1,TSEN15,TSEN2,VARS1,YARS2 |
| GO_MITOCHONDRIAL_TRANSLATION | 0.0e+00 | 0.0e+00 | 900 | 137 | 22 | MPV17L2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MTG1,NDUFA7,RPUSD3,YARS2 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1117 | 62 | ACSL4,ACSL5,ADCY7,ADSL,AHCY,ALDH1A1,ALG2,ALG3,APCS,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,B4GALT2,B4GALT7,CMAS,DNPH1,DPAGT1,EDEM2,EXTL3,G6PC3,GALNT15,GCDH,GCNT1,GUSB,HAS2,IDUA,IMPDH2,KRTCAP2,LCMT2,MACROD1,MGAT1,MGAT2,MPI,MUC1,NANP,NUP37,OARD1,OST4,PANK4,PARK7,PDK4,PEMT,PIGC,PIGO,PIGV,PORCN,PRKAG2,PUDP,PYURF,RFK,RNF139,SCCPDH,SEH1L,SMPD2,SPHK2,SUMF2,TRMT12,UCK2,UQCC3 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 900 | 1741 | 81 | ABCG1,ABLIM3,ADGRE2,AGK,AKTIP,ANKRD28,AP1S1,ARF6,ARNTL,ARV1,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,BORCS5,CCDC88B,CES1,DNAJC19,DPY30,EDEM2,ENTR1,EPG5,FERMT1,FIS1,FMN2,FOXF1,GEMIN7,GGA1,GNPAT,GRIA1,IFT57,IFT74,KIF17,KLHL12,LAT2,LEPROTL1,LONP2,LTBP2,MILR1,MIPEP,MKKS,MVB12A,NCBP2,NEDD4,NUP37,NUTF2,PARK7,PARL,PCID2,PEX12,PIK3CG,PRKAG2,RAB11A,RAC2,RANGRF,RHBDD1,RNF139,RPAIN,SCG5,SEC22C,SEH1L,SERPINA1,SNX17,SPHK2,TAP1,THOC7,TMCO6,TMED3,TRAPPC11,TRAPPC4,TRIM27,TSPO,TYSND1,UBAC2,UBL5,VAMP2,VAMP4,WWC1,ZDHHC4,ZNF593 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1724 | 80 | ABCG1,ADCY7,AIFM1,AIMP2,AKTIP,ARNTL,BCL3,BDNF,BIRC3,C1QTNF1,CALM2,CAMKK2,CAMTA1,CASP1,CAV1,CCND1,DAP,DIABLO,DLC1,EDEM2,EGFR,EGR1,EIF2B5,F12,FBXO4,FIS1,GGA1,GHRL,GSDME,IFI16,IFT57,IGFBP4,IMPACT,JMJD4,LIF,LPCAT1,LRP8,MAD2L2,MAPKAP1,MARCO,MEFV,MIF4GD,MLST8,MPV17L2,MTOR,MUC1,MUL1,NEDD4,NELFE,PARK7,PDGFRA,PEMT,PIK3CG,PKN1,PLGRKT,POLR2G,PPM1F,PRDM12,PRKAG2,PSMD10,PTPRJ,RELN,RHBDD1,RNF139,RNF41,ROR1,RPUSD3,RYK,SAA1,SERPINB3,SFRP2,SPHK2,STK24,STK39,TADA2A,TEK,TLR3,WDR61,WWC1,XDH |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 900 | 1258 | 65 | BDNF,CALM2,CAMKK2,CAMKMT,CAV1,CLK2,CSKMT,CSNK1G2,DHPS,DPH6,DPY30,DYDC1,EGFR,EGR1,FKBP2,GHRL,HMBS,KRTCAP2,LIF,LIPT1,LRP8,MAD2L2,MAPKAP1,MAST4,MCRS1,MGAT1,MGAT2,MLST8,MTOR,MUC1,MUL1,NAA10,NEK6,NELFE,NLK,NTMT1,NUP37,OST4,PARK7,PDF,PDGFRA,PKN1,PKN2,PPM1F,PRDM12,PRKAG2,PTPRJ,QPCTL,RELN,ROR1,RUVBL1,RYK,SEH1L,SFRP2,SPHK2,STK39,TADA2A,TAF9,TEK,TTL,TTLL12,TTLL5,WDR5B,WDR61,ZDHHC4 |
| GO_COFACTOR_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 449 | 36 | AASDHPPT,ACSL4,ACSL5,AHCY,APIP,ATIC,CLYBL,CNDP2,COQ3,COQ7,EGFR,GCDH,GCH1,GGT5,GSS,HAGH,HBA2,HMBS,ISCU,MMUT,NADK2,NFU1,NNMT,PANK4,PARK7,PARP10,PCBD2,PDK4,PDZD11,PEMT,QDPR,RAC2,RFK,RSAD1,TMEM14C,TSPO |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 900 | 1863 | 82 | AKAP7,ALPK1,APIP,ARF6,ARHGEF9,ARNTL,BAG5,BCL3,BIRC3,C1QTNF1,C1QTNF12,CALM2,CAMK2N1,CAMTA1,CARD16,CASP1,CAV1,DLC1,EGFR,EPS8,F2RL3,FIS1,GBP1,GHRL,GSDME,IGFBP4,IL18R1,LEMD3,LIF,LURAP1,MAPKAP1,MARCO,MLST8,MRAP,MTOR,MUC1,MUL1,NEDD4,NEK6,NELFE,NPRL2,NPRL3,NR3C2,P2RX5,PARK7,PDGFRA,PIK3CG,PKN1,PRKAG2,PSMD10,PTPMT1,PTPRJ,RAC2,RASA1,RASIP1,RELN,RNF34,RNF41,ROR1,RXFP2,RYK,SAA1,SEH1L,SERPINB3,SFRP2,SPHK2,SPRY1,SRI,STK39,SYDE2,TAF9,TEK,TLR3,TMEM101,TP53RK,TRIAP1,TTC5,TXNDC12,WTIP,WWC1,WWC3,XDH |
| GO_MITOCHONDRIAL_TRANSLATIONAL_TERMINATION | 0.0e+00 | 0.0e+00 | 900 | 89 | 17 | MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33 |
| GO_TRANSLATIONAL_ELONGATION | 0.0e+00 | 0.0e+00 | 900 | 135 | 20 | DPH6,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,SECISBP2,ZNF598 |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 900 | 856 | 50 | AKTIP,ALKBH2,BABAM2,BCL3,CCND1,CEP63,CHCHD6,CINP,COPS6,COPS7A,DDB2,EGFR,ENDOV,ERCC1,FANCE,FBXO4,FH,FMN2,H4C11,IFI16,INO80C,MACROD1,MAD2L2,MCRS1,MCTS1,MRPS11,MUC1,NEDD4,NSMCE1,NSMCE4A,OARD1,PARK7,PARP10,PMS2P1,PMS2P6,POLR2G,POLR2I,PSMD10,RPAIN,RUVBL1,SFRP2,SLX1B,TAF9,TRIAP1,TTC5,USP45,WDR70,WRNIP1,ZBTB5,ZSWIM7 |
| GO_RNA_PROCESSING | 0.0e+00 | 0.0e+00 | 900 | 917 | 52 | C9orf64,CDK13,CLK2,CMTR1,CMTR2,CSTF1,DUS1L,EGFR,ELP3,ELP4,EXOSC7,GEMIN7,HNRNPA0,HNRNPF,HNRNPLL,LCMT2,LSM2,METTL15,METTL6,MRPS11,NCBP2,NELFE,NHP2,NPM3,OSGEPL1,PCBP1,POLR2G,POLR2I,RBMXL1,RPP38,RPRD1A,RPUSD2,RPUSD3,SEPHS2,SF3B3,SF3B5,SMAD1,TBRG4,THADA,THOC7,TP53RK,TRMT10B,TRMT112,TRMT12,TRMT6,TRPT1,TSEN15,TSEN2,TUT1,UBL5,USP4,ZCRB1 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 900 | 1114 | 58 | AIMP2,AKTIP,ANAPC7,BABAM2,BAG5,BIRC3,CAV1,COPS6,COPS7A,DCAF11,DCAF17,DCAF7,DDB2,EGR1,FBXO4,HDAC8,INO80C,IRF2BP1,IRF2BPL,KLHL12,LNX1,MAD2L2,MARCHF10,MCRS1,MIB1,MTOR,MUL1,NEDD4,NSMCE1,NUP37,PARK7,PARP10,PCGF1,PEX12,PJA1,PSMB10,PSMB8,PSMB9,PSMD10,RNF139,RNF214,RNF34,RNF41,RSPRY1,RUVBL1,SEH1L,SMAD1,TRIM2,TRIM27,TRIM47,TSPO,USP19,USP20,USP4,USP45,WDR61,WDR70,ZNF598 |
| GO_COFACTOR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 230 | 25 | ACSL4,ACSL5,ATIC,CNDP2,COQ3,COQ7,GCDH,GCH1,GGT5,GSS,HAGH,HMBS,ISCU,NADK2,NFU1,NNMT,PANK4,PARP10,PCBD2,PDK4,QDPR,RFK,RSAD1,TMEM14C,TSPO |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 671 | 43 | ACSL4,ACSL5,ADCY7,ADSL,ALG2,ALG3,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,B4GALT2,B4GALT7,DPAGT1,EXTL3,GALNT15,GCDH,GCNT1,HAS2,IMPDH2,KRTCAP2,LCMT2,MGAT1,MGAT2,MPI,MUC1,NANP,OST4,PANK4,PDK4,PIGC,PIGO,PIGV,PRKAG2,PUDP,PYURF,RFK,SCCPDH,SPHK2,TRMT12,UCK2,UQCC3 |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 594 | 40 | ACSL4,ACSL5,ADCY7,ADSL,AGK,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CHPT1,CRLS1,DPAGT1,GCDH,GCH1,GNPAT,IMPDH2,LPCAT1,NADK2,NNMT,PANK4,PARP10,PDK4,PEMT,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PRKAG2,PTPMT1,PYURF,RFK,SGMS2,SPHK2,TAMM41,UCK2,UQCC3 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1033 | 55 | ACSL4,ACSL5,ADCY7,ADSL,AGK,ALDH1A1,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CHPT1,CRLS1,DNPH1,DPAGT1,G6PC3,GCDH,GCH1,GDA,GNPAT,IMPDH2,INPP1,LPCAT1,NADK2,NAPEPLD,NNMT,NUP37,PANK4,PARK7,PARP10,PDGFRA,PDK4,PEMT,PGP,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PRKAG2,PTPMT1,PUDP,PYURF,RFK,SEH1L,SGMS2,SMPD2,SPHK2,TAMM41,TEK,UCK2,UQCC3,XDH |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 900 | 1124 | 57 | ADCY7,ALPK1,APCS,BIRC3,C1QTNF1,C1QTNF12,C2CD4A,CAMKMT,CARD16,CASP1,CAV1,CCN4,CCR4,CHID1,CYP19A1,EGFR,ELMOD2,EPG5,F12,FAM3A,FOXF1,GHRL,IFI16,IL1RL1,IL20RB,LRP8,LSM14A,MARCO,MEFV,MGLL,MKKS,MTOR,MUC1,MUL1,NAPEPLD,NLRC5,PARK7,PDGFRA,PIK3CG,PLAU,PPM1F,PSMB10,PSMB8,PSMB9,PSMD10,RAC2,RAET1E,RYK,SAA1,SBNO2,SERPINB4,SLAMF8,STK24,STK39,TEK,TLR3,TTLL12 |
| GO_METHYLATION | 0.0e+00 | 0.0e+00 | 900 | 366 | 30 | AHCY,CAMKMT,CMTR1,CMTR2,COQ3,CSKMT,DPY30,DYDC1,FAM86B1,FAM86B2,FAM86C2P,GRHL2,LCMT2,METTL15,METTL5,METTL6,NELFE,NNMT,NTMT1,PEMT,PRDM12,PRDM8,THADA,TRMT10B,TRMT112,TRMT12,TRMT6,TTLL12,WDR5B,WDR61 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1870 | 78 | ABLIM3,ARNTL,BABAM2,BCL3,CAMKK2,CAMTA1,CDK13,CHURC1,CREB3L4,CTAG2,DEAF1,E2F5,EGFR,EGR1,ERCC1,ESRRA,ETV1,FBXO4,FMN2,FOXF1,GRHL2,H1-10,HDAC8,HNRNPLL,HOXC4,IFI16,IFT74,IKZF2,IRF2,IRF2BP1,IRF2BP2,IRF2BPL,JUNB,LHX1,LIF,MAD2L2,MCRS1,MICAL2,MLXIP,MTOR,MUC1,NCBP2,NELFE,NFE4,NLRC5,PARK7,PCBD2,PCBP1,PCID2,PKN1,PLAG1,POLR2G,PRRX1,PTGES2,RBMXL1,RERE,RUVBL1,SATB2,SBNO2,SFRP2,SLX1B,SMAD1,SS18L2,TADA2A,TAF9,TBX2,TEF,TFAP2B,TLR3,TRIAP1,TRMT112,TTC5,WDR61,WWC1,ZNF501,ZNF564,ZNF593,ZSCAN21 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 0.0e+00 | 900 | 802 | 46 | ABHD17C,ABLIM3,ADGRE2,ARF6,ARV1,BDNF,BORCS5,C1QTNF12,CALM2,CAV1,EDEM2,EGFR,ENTR1,F2RL3,FBXO4,FERMT1,FIS1,FOXF1,GBP1,GHRL,HDAC8,ISCU,LEPROTL1,LIF,LYPLA1,MCRS1,MRAP,NCBP2,NEDD4,NUTF2,OXCT1,P2RX5,PARK7,PARL,PPM1F,RAB11A,RAC2,RANGRF,RNF139,SPHK2,SRI,TTL,UBAC2,UBL5,VAMP2,WWC1 |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 900 | 547 | 37 | AIFM1,APEH,CAMKK2,CAV1,EPG5,EPS8,FIS1,FRAT2,JMJD4,KIF9,MCTS1,MICAL2,MMP19,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,MUL1,NEK6,PARK7,RNF41,SNAP29,TRMT112,TSPO |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1710 | 73 | ABLIM3,ARNTL,BCL3,CAMKK2,CAMTA1,CDK13,CHURC1,CREB3L4,CTAG2,DEAF1,E2F5,EGFR,EGR1,ESRRA,ETV1,FOXF1,GRHL2,H1-10,HDAC8,HNRNPLL,HOXC4,IFI16,IFT74,IKZF2,IRF2,IRF2BP1,IRF2BP2,IRF2BPL,JUNB,LHX1,LIF,MAD2L2,MCRS1,MICAL2,MLXIP,MTOR,MUC1,NCBP2,NELFE,NFE4,NLRC5,PARK7,PCBD2,PCBP1,PCID2,PKN1,PLAG1,POLR2G,PRRX1,PTGES2,RBMXL1,RERE,RUVBL1,SATB2,SBNO2,SFRP2,SMAD1,SS18L2,TADA2A,TAF9,TBX2,TEF,TFAP2B,TLR3,TRIAP1,TRMT112,TTC5,WDR61,WWC1,ZNF501,ZNF564,ZNF593,ZSCAN21 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 0.0e+00 | 900 | 532 | 36 | ADSL,ALDH1A1,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,COX17,COX8A,CYP19A1,FH,GYG1,ISCU,MDH2,MTOR,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,NUP37,OXCT1,PARK7,PRKAG2,PTGES2,QDPR,SDHAF4,SEH1L,SH3BGRL3,SLC25A22,SLC27A5,SPHK2,STEAP4,UQCC3,UQCRFS1,XDH |
| GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 900 | 96 | 16 | COA4,COX14,COX17,FOXRED1,NDUFA7,NDUFAF8,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PET117,SCO1,SDHAF1,SDHAF4,SMIM20,UQCC3 |
| GO_TRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 900 | 128 | 18 | C9orf64,DUS1L,ELP3,ELP4,LCMT2,METTL6,OSGEPL1,RPP38,SEPHS2,THADA,TP53RK,TRMT10B,TRMT112,TRMT12,TRMT6,TRPT1,TSEN15,TSEN2 |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 900 | 1765 | 74 | ADCY7,ADGRE2,ADGRE5,AHCY,ALPK1,APCS,BATF2,BCL3,BIRC3,C1QTNF12,C2CD4A,CASP1,CAV1,CCDC88B,CCN4,CCR4,CHID1,CLDN1,CYP19A1,DEAF1,EGFR,EGR1,ELMOD2,EPG5,F12,FAM3A,FOXF1,GBP1,GCH1,GGT5,GHRL,GSDMD,HNRNPA0,IFI16,IFI44L,IFITM1,IGFBP4,IL18R1,IL1RL1,IL20RB,IRF2,LRP8,LSM14A,MARCO,MEFV,MGLL,MUC1,MUL1,NAPEPLD,NLRC5,PARK7,PIK3CG,PLGRKT,PSMB10,PSMB8,PSMB9,PSMD10,RAET1E,SAA1,SBNO2,SDHAF4,SEH1L,SERPINA1,SERPINB4,SLAMF8,STK39,TAP1,TEK,TLR3,TRIM27,TTLL12,VCAM1,WFDC12,WRNIP1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1988 | 80 | ABLIM3,ARNTL,BCL3,CAMKK2,CAMTA1,CDK13,CHURC1,CREB3L4,CTAG2,DEAF1,E2F5,EGFR,EGR1,EIF2B5,ESRRA,ETV1,FBXO4,FOXF1,GRHL2,H1-10,HAS2,HDAC8,HOXC4,IFI16,IFT74,IKZF2,IMPACT,IRF2,IRF2BP1,IRF2BP2,IRF2BPL,JMJD4,JUNB,LHX1,LIF,MAD2L2,MCRS1,MICAL2,MIF4GD,MLXIP,MPV17L2,MTOR,MUC1,NELFE,NFE4,NLRC5,PARK7,PCBD2,PCBP1,PCID2,PEMT,PKN1,PLAG1,POLR2G,PRRX1,PTGES2,RERE,RPUSD3,RUVBL1,SATB2,SBNO2,SFRP2,SMAD1,SMPD2,SPHK2,SS18L2,TADA2A,TAF9,TBX2,TEF,TFAP2B,TLR3,TRIAP1,TTC5,WDR61,WWC1,ZNF501,ZNF564,ZNF593,ZSCAN21 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 900 | 804 | 45 | ADCY7,ALPK1,APCS,BIRC3,C1QTNF12,C2CD4A,CASP1,CAV1,CCN4,CHID1,CYP19A1,EGFR,ELMOD2,EPG5,F12,FAM3A,FOXF1,GHRL,IFI16,IL1RL1,IL20RB,LRP8,LSM14A,MARCO,MEFV,MGLL,MUC1,MUL1,NAPEPLD,NLRC5,PARK7,PIK3CG,PSMB10,PSMB8,PSMB9,PSMD10,RAET1E,SAA1,SBNO2,SERPINB4,SLAMF8,STK39,TEK,TLR3,TTLL12 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 1301 | 60 | ABHD17C,AGAP3,AHCY,ANAPC7,ARNTL,ASAH2B,BAG5,CAV1,CBS,CYP2D6,DCAF11,DNPH1,EDEM2,EGFR,FBXO39,FBXO4,FMN2,GCAT,GCDH,GDA,GGA1,GGACT,GGT5,GUSB,HIBADH,IDUA,LNX1,LONP2,LPCAT1,LYPLA1,MAD2L2,MTOR,MVB12A,NEDD4,PARK7,PHYKPL,PJA1,PPM1K,PSMB10,PSMB8,PSMB9,PSMD10,QDPR,RHBDD1,RNF139,RNF34,RNF41,RSPRY1,SCO1,SDSL,SF3B3,SMPD2,TAF9,TRIM2,UBAC2,USP19,USP20,USP4,USP45,XDH |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 900 | 1545 | 67 | ABLIM3,ACSL4,ARF6,B9D1,BAG5,BDNF,BRK1,BTBD3,CAV1,CBY1,CC2D2A,CCDC113,CCNO,CDC14C,CDC42EP1,CEP63,CFAP298,CPLANE2,DNAAF2,DNAH5,E2F5,EGFR,ENTR1,EPS8,ETV1,FRY,GHRL,IFT57,IFT74,IMPACT,KIF17,LHX1,LRP8,LRRC6,MKKS,MTOR,MTSS1,MUL1,NCAM2,NCS1,NEDD4,NEGR1,PKN2,PLXNA2,PRDM12,PRICKLE3,PRRX1,PTPRG,RAB11A,RAC2,RELN,RERE,ROBO4,ROR1,RYK,S100A6,SFRP2,SNAP29,SS18L2,STK24,TMEM106B,TMEM231,TPRN,TRAPPC4,TSPO,TTL,WTIP |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 0.0e+00 | 900 | 912 | 48 | AIMP2,AKTIP,ANAPC7,BAG5,BIRC3,CAV1,DCAF11,DCAF17,DCAF7,DDB2,EGR1,FBXO4,HDAC8,IRF2BP1,IRF2BPL,KLHL12,LNX1,MAD2L2,MARCHF10,MIB1,MTOR,MUL1,NEDD4,NSMCE1,NUP37,PARK7,PARP10,PCGF1,PEX12,PJA1,PSMB10,PSMB8,PSMB9,PSMD10,RNF139,RNF214,RNF34,RNF41,RSPRY1,SEH1L,TRIM2,TRIM27,TRIM47,TSPO,USP4,WDR61,WDR70,ZNF598 |
| GO_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 900 | 735 | 42 | AIFM1,BAG5,BIRC3,CAMK2N1,CARD16,CASP1,CAV1,CSTA,DAP,DIABLO,DLC1,EDEM2,F12,FIS1,IFI16,IFT57,MEFV,MUL1,PARK7,PARL,PCID2,PLGRKT,PPM1F,PSMB8,PSMB9,PSMD10,RHBDD1,RNF139,RNF34,SCO1,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPINK6,TAF9,TFAP2B,TRIAP1,UBAC2,USP19,WFDC12,XDH |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 710 | 41 | ABCG1,ACSL4,AGK,ALDH1A3,ARV1,ASAH2B,CES1,CHPT1,CRLS1,CSNK1G2,CYP19A1,CYP2D6,CYP4A11,DPAGT1,EGR1,FAM3A,GNPAT,LPCAT1,MGLL,MTOR,PCK2,PDK4,PEMT,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PRKAG2,PTGES2,PTPMT1,PYURF,SCCPDH,SGMS2,SLC27A5,SMPD2,SPHK2,SPTSSB,TAMM41,TSPO |
| GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 900 | 219 | 22 | APEH,EPS8,JMJD4,MICAL2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,TRMT112 |
| GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 200 | 21 | AASDHPPT,AGMAT,AHCY,APIP,ASL,CBS,CBSL,GCAT,GCDH,HIBADH,KYAT3,MMUT,NIT2,PARK7,PEMT,PHYKPL,PYCR2,PYCR3,QDPR,SDSL,SEPHS2 |
| GO_RNA_MODIFICATION | 0.0e+00 | 0.0e+00 | 900 | 161 | 19 | C9orf64,CMTR1,CMTR2,DUS1L,ELP3,ELP4,LCMT2,METTL15,METTL6,NHP2,OSGEPL1,RPUSD2,RPUSD3,SEPHS2,THADA,TRMT10B,TRMT112,TRMT12,TRMT6 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 627 | 38 | ACSL4,ACSL5,ADCY7,ADSL,AHCY,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,DNPH1,DPAGT1,GCDH,GDA,IMPDH2,MACROD1,MGAT1,MPI,MTOR,NADK2,NNMT,NUP37,OARD1,PANK4,PARK7,PARP10,PDK4,PEMT,PRKAG2,PUDP,RFK,SEH1L,SPHK2,TAMM41,UCK2,UQCC3,XDH |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 900 | 1869 | 75 | ACSL4,ALPK1,ARNTL,BDNF,BIRC3,C1QTNF1,C1QTNF12,CA2,CALM2,CAMTA1,CARD16,CASP1,CAV1,CCN4,CSNK1G2,CYP19A1,CYP1B1,EGFR,EPS8,F2RL3,FERMT1,FIS1,GHRL,GSDME,IGFBP4,IL18R1,LIF,LRG1,LSM14A,LURAP1,MARCO,MLST8,MRAP,MTOR,MUL1,NEDD4,NEK6,NELFE,NLRC5,NR3C2,NRARP,OXCT1,P2RX5,PARK7,PDGFRA,PIK3CG,PKN1,PLEKHA4,PRRX1,PSMB10,PSMB8,PSMB9,PSMD10,PTGDR2,PTPRJ,RAC2,RELN,ROR1,RUVBL1,RXFP2,RYK,SAA1,SEH1L,SFRP2,SLC24A1,SPHK2,SRI,SRPX,STK39,TEK,TLR3,TMEM101,VAMP2,WWC1,XDH |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 900 | 1235 | 57 | ADSL,AHCY,AIFM1,B4GALT2,BABAM2,BAG5,BCL3,CA2,CAMKMT,CARD16,CASP1,CAV1,CCND1,CCR4,CLDN1,CLK2,DDB2,DEAF1,EGFR,EGR1,EIF2B5,ERCC1,ETV1,FBXO4,FIS1,FMN2,GHRL,IFI16,IMPACT,JUNB,MKKS,MLST8,MTOR,NEDD4,NUP37,PKD1L1,PKN1,PLAU,PRDM12,PSMB10,PSMB8,PSMB9,PSMD10,RHBDD1,RNF34,SEH1L,SFRP2,SLC24A1,SMPD2,STK39,TEK,TLR3,TRIAP1,TSPO,USP19,VCAM1,WTIP |
| GO_NCRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 900 | 471 | 32 | AIMP2,C9orf64,DUS1L,ELP3,ELP4,EXOSC7,FARSA,LCMT2,METTL15,METTL6,MRPS11,NHP2,NPM3,OSGEPL1,PPA1,PPA2,RPP38,RPUSD2,SEPHS2,SMAD1,THADA,TP53RK,TRMT10B,TRMT112,TRMT12,TRMT6,TRPT1,TSEN15,TSEN2,TUT1,VARS1,YARS2 |
| GO_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 900 | 326 | 26 | APEH,CAV1,EPG5,EPS8,FRAT2,JMJD4,MICAL2,MRPL20,MRPL24,MRPL27,MRPL36,MRPL40,MRPL50,MRPL51,MRPL53,MRPL54,MRPL57,MRPL58,MRPS11,MRPS16,MRPS18A,MRPS21,MRPS23,MRPS33,SNAP29,TRMT112 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 900 | 1198 | 55 | ABLIM3,ARNTL,BCL3,CAMTA1,CDK13,CREB3L4,CTAG2,E2F5,EGFR,EGR1,ESRRA,ETV1,FOXF1,GRHL2,HDAC8,HOXC4,IFI16,IFT74,IKZF2,IRF2,IRF2BP1,IRF2BP2,IRF2BPL,JUNB,LHX1,LIF,MCRS1,MICAL2,MLXIP,MUC1,NELFE,NFE4,NLRC5,PARK7,PCBP1,PLAG1,PRRX1,SATB2,SBNO2,SFRP2,SMAD1,SS18L2,TAF9,TBX2,TEF,TFAP2B,TLR3,TRIAP1,TTC5,WDR61,WWC1,ZNF501,ZNF564,ZNF593,ZSCAN21 |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 1.0e-07 | 900 | 1894 | 74 | ABCG1,ABLIM3,ACSL4,ADGRE2,ARF6,ARNTL,ARV1,BORCS5,C1QTNF1,C1QTNF12,CA2,CALM2,CARD16,CASP1,CAV1,CCN4,COX17,CPLANE2,CYP19A1,CYP4A11,EDEM2,EGFR,F2RL3,FERMT1,FIS1,FOXF1,GBP1,GHRL,GRIA1,GSDMD,IL1RL1,ISCU,KCNG2,LIF,LYPLA1,MIB1,MTOR,MUL1,NCBP2,NCS1,NEDD4,NKAIN2,NUTF2,ORAI1,OXCT1,P2RX5,PARK7,PARL,PIK3CG,PPM1F,PRKAG2,PTPRJ,RAB11A,RAC2,RANGRF,RELN,RNF139,SAA1,SCG5,SNX17,SPHK2,SRGN,SRI,STK39,TFAP2B,THADA,TRIAP1,TRIM27,TSPO,UBAC2,UBL5,VAMP2,VAMP4,WWC1 |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 1.0e-07 | 900 | 1425 | 61 | ABI3BP,ADGRE2,ADGRE5,ARF6,C1QTNF1,C2CD4A,CAV1,CCDC88B,CCN4,CDC42EP1,CDH10,CDH19,CGREF1,CLDN1,COL17A1,COL8A1,CSTA,CYP1B1,DLC1,EGFR,FERMT1,FIBP,FOXF1,GBP1,GCNT1,GRHL2,HAS2,IFT74,IL20RB,ITGBL1,KIFC3,MAD2L2,MPZL2,MTSS1,MUC1,MYBPC1,NCAM2,NECTIN3,NEGR1,NINJ1,NRARP,PDCD1LG2,PDGFRA,PIK3CG,PKD1L1,PKN2,PLAU,PLXNA2,PPM1F,PTPRJ,RAC2,RASA1,RELN,ROBO4,SAA1,SFRP2,SRPX,TEK,TMEM131L,TPBG,VCAM1 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 1.0e-07 | 900 | 1880 | 73 | ADCY7,AIMP2,AKTIP,APIP,ARNTL,BAG5,BDNF,BIRC3,C1QTNF1,CALM2,CAMK2N1,CAMKK2,CAMTA1,CAV1,CCND1,CCNO,DLC1,EGFR,EGR1,ELP3,ELP4,FBXO4,FRY,GBP1,GHRL,GSDME,HDAC8,IGFBP4,IMPACT,LIF,LRP8,MAD2L2,MAPKAP1,MARCO,MLST8,MTOR,MUC1,MUL1,NELFE,PARK7,PARP10,PDGFRA,PIK3CG,PKN1,PPM1F,PRDM12,PRKAG2,PSMD10,PTPRJ,RAC2,RASIP1,RELN,RNF41,ROR1,RYK,SAA1,SERPINB3,SFRP2,SPHK2,SPRY1,STK24,STK39,TADA2A,TEK,TLR3,TRIM27,TRPT1,TSPO,USP4,WDR61,WDR70,WWC1,XDH |
| GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 900 | 654 | 37 | AASDHPPT,ACOXL,ACSL4,ACSL5,ALDH1A3,ARV1,ASAH2B,CAV1,CES1,CYP1B1,CYP2D6,CYP4A11,FAAH2,GCDH,GGT5,GNPAT,GRHPR,HAGH,IDUA,LONP2,LYPLA1,MGLL,MMUT,MTOR,NIT2,NUP37,PARK7,PCK2,PDK4,PDZD11,PRKAG2,PTGES2,SEH1L,SLC27A3,SLC27A5,TYSND1,ZADH2 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 2.0e-07 | 900 | 1280 | 56 | ARNTL,BCL3,CAV1,CBY1,CCND1,CGGBP1,DAP,DEAF1,E2F5,EGR1,EID2B,ESRRA,FOXF1,H1-10,H3-3B,H4C11,HDAC8,HES4,HES7,IFI16,IMPACT,IRF2,IRF2BP1,IRF2BPL,JUNB,LHX1,MAD2L2,MUC1,NEDD4,NELFB,NELFE,NRARP,PCGF1,PPM1F,PRRX1,PSMD10,RERE,RIOX2,SATB2,SBNO2,SCMH1,SFRP2,TBX2,TFAP2B,TGIF2,TRIM27,TRPS1,WTIP,WWC1,WWC3,ZBTB5,ZC3H6,ZNF282,ZNF501,ZNF564,ZNF706 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 2.0e-07 | 900 | 1716 | 68 | ADRA1D,AIMP2,ATP5F1A,B4GALT7,BRK1,CAMK2N1,CAV1,CCDC88B,CCN4,CCND1,CDK13,CGREF1,CLDN1,COX17,CYP1B1,DEAF1,DHPS,DLC1,EGFR,EGR1,ESRRA,FBXO4,FERMT1,FOXF1,GHRL,GSDME,HAS2,IFITM1,IFT57,IFT74,IL20RB,LHX1,LIF,LRG1,MCTS1,MTOR,MTSS1,NRARP,PARP10,PDCD1LG2,PDF,PDGFRA,PEMT,PKN1,PLAG1,PLAU,PRRX1,PTGDR2,PTPRJ,RAC2,RNF139,RNF41,RXFP2,S100A6,SERPINB3,SFRP2,SPHK2,SPRY1,SRPX,TBRG4,TBX2,TEK,TFAP2B,TMEM131L,TSPO,VCAM1,WDR13,XDH |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 2.0e-07 | 900 | 1287 | 56 | AGAP3,AIFM1,ALDH1A1,APCS,BDNF,BIRC3,CALM2,CARD16,CASP1,CAV1,CSTA,DAP,DIABLO,DLC1,DNAJC19,EGFR,ELMOD2,FIS1,IFI16,IFT57,LRCH1,MEFV,MKKS,MLST8,MMUT,MTOR,MUL1,NPRL2,NPRL3,PARK7,PCID2,PDGFRA,PLXNA2,PPM1F,PSMB8,PSMB9,RASA1,RASIP1,RGS16,RIN1,RNF34,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPHK2,SPINK6,SPOCD1,SPRY1,SYDE2,TFAP2B,TMEM132D,TRIAP1,WFDC12,XDH,ZCCHC9 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 900 | 1470 | 61 | ARNTL,BCL3,CAV1,CBY1,CCND1,CGGBP1,DAP,DEAF1,E2F5,EGR1,EID2B,ERCC1,ESRRA,FOXF1,H1-10,H3-3B,H4C11,HDAC8,HES4,HES7,HNRNPA0,IFI16,IMPACT,IRF2,IRF2BP1,IRF2BPL,JUNB,LHX1,MAD2L2,MTOR,MUC1,NEDD4,NELFB,NELFE,NRARP,PCGF1,PPM1F,PRRX1,PSMD10,RERE,RIOX2,SATB2,SBNO2,SCMH1,SECISBP2,SFRP2,SLX1B,TBX2,TFAP2B,TGIF2,TRIM27,TRPS1,WTIP,WWC1,WWC3,ZBTB5,ZC3H6,ZNF282,ZNF501,ZNF564,ZNF706 |
| GO_MITOCHONDRIAL_TRANSPORT | 0.0e+00 | 2.0e-07 | 900 | 258 | 22 | ABLIM3,AGK,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,DNAJC19,FIS1,MIPEP,MTX2,MUL1,NAIF1,PARL,PRKAG2,RAC2,SLC25A15,SLC25A22,STPG1,TMEM14C,TSPO,UBL5 |
| GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 2.0e-07 | 900 | 282 | 23 | ACSL4,ACSL5,ADCY7,ADSL,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,GCDH,IMPDH2,NADK2,NNMT,PANK4,PARP10,PDK4,PRKAG2,RFK,SPHK2,TAMM41,UCK2,UQCC3 |
| GO_RIBOSE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 3.0e-07 | 900 | 192 | 19 | ACSL4,ACSL5,ADCY7,ADSL,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,GCDH,IMPDH2,PANK4,PDK4,PRKAG2,RFK,SPHK2,UCK2,UQCC3 |
| GO_INFLAMMATORY_RESPONSE | 0.0e+00 | 3.0e-07 | 900 | 765 | 40 | ADCY7,ADGRE2,ADGRE5,AHCY,APCS,BIRC3,C1QTNF12,C2CD4A,CASP1,CCN4,CCR4,CHID1,CYP19A1,EGFR,F12,FOXF1,GGT5,GHRL,GSDMD,HNRNPA0,IFI16,IGFBP4,IL18R1,IL1RL1,IL20RB,MEFV,MGLL,NAPEPLD,PARK7,PIK3CG,PLGRKT,SAA1,SBNO2,SEH1L,SERPINA1,SLAMF8,STK39,TEK,TLR3,VCAM1 |
| GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 0.0e+00 | 3.0e-07 | 900 | 238 | 21 | AIFM1,BIRC3,CARD16,CASP1,DAP,DIABLO,DLC1,FIS1,IFI16,IFT57,MEFV,MUL1,PARK7,PCID2,PPM1F,PSMB9,RNF34,SFRP2,TFAP2B,TRIAP1,XDH |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 3.0e-07 | 900 | 1673 | 66 | ARNTL,BCL3,C1QTNF12,CAV1,CBY1,CCND1,CGGBP1,CLK2,DAP,DEAF1,E2F5,EGR1,EID2B,EIF4E2,ESRRA,FAM3A,FOXF1,GHRL,H1-10,H3-3B,H4C11,HDAC8,HES4,HES7,IFI16,IMPACT,IRF2,IRF2BP1,IRF2BPL,JUNB,LHX1,LPCAT1,MAD2L2,MUC1,NEDD4,NELFB,NELFE,NRARP,PARK7,PCGF1,PGP,PPM1F,PRRX1,PSMD10,RERE,RIOX2,RNF139,SATB2,SBNO2,SCMH1,SFRP2,TBX2,TFAP2B,TGIF2,TRIM27,TRPS1,TSPO,WTIP,WWC1,WWC3,ZBTB5,ZC3H6,ZNF282,ZNF501,ZNF564,ZNF706 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 4.0e-07 | 900 | 1036 | 48 | APCS,ARF6,BRK1,CDC42EP1,COA4,COPS7A,COX14,COX17,DDB2,DNAAF2,DNAH5,EPS8,FOXRED1,GEMIN7,H1-10,H3-3B,H4C11,LRRC6,MCTS1,MEFV,MKKS,MLST8,MRPL20,MRPS11,MTOR,NDUFA7,NDUFAF8,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PET117,PSMD10,PSMG4,RANGRF,RASA1,RUVBL1,SCO1,SDHAF1,SDHAF4,SMAD1,SMIM20,SNAP29,TAF9,TRIM27,UQCC3,USP4,VAMP4 |
| GO_SECRETION | 0.0e+00 | 4.0e-07 | 900 | 1680 | 66 | ABCG1,ACSL4,ADGRE2,ADGRE5,APEH,ARF6,ARNTL,C1QTNF1,C1QTNF12,CA2,CARD16,CASP1,CAV1,CCN4,CCND1,CDK13,CHID1,CPLANE2,CYP19A1,CYP4A11,EGFR,EXOC6,FERMT1,FOXF1,GBP1,GHRL,GSDMD,GUSB,GYG1,IL1RL1,IMPDH2,KCNG2,LAT2,LIF,LPCAT1,LRG1,LTBP2,MILR1,NCS1,NIT2,OXCT1,PARK7,PDZD11,PIK3CG,PLAU,PTGES2,PTPRJ,RAB11A,RAC2,SAA1,SCCPDH,SCG5,SERPINA1,SERPINB3,SLC1A7,SNAP29,SPHK2,SRGN,SRI,STEAP2,STK39,SYNGR2,TFAP2B,TRIM27,VAMP2,XDH |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 4.0e-07 | 900 | 1427 | 59 | ARNTL,BAG5,BCL3,BDNF,CALM2,CAMK2N1,CARD16,CAV1,CBY1,DLC1,EGFR,EGR1,FERMT1,GBP1,GHRL,GRIA1,HHIP,IGFBP4,KLHL12,LEMD3,LIF,MAD2L2,MAPKAP1,MRAP,MTOR,MUC1,MUL1,NEDD4,NLK,NLRC5,NPRL2,NPRL3,NRARP,PARK7,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RASA1,RASIP1,RGS16,RNF34,SERPINB3,SFRP2,SLC24A1,SPRY1,SRI,TAF9,TLR3,TMEM131L,TRIAP1,TTLL12,TXNDC12,UBAC2,WTIP,WWC1,WWC3,XDH |
| GO_TRNA_MODIFICATION | 0.0e+00 | 5.0e-07 | 900 | 86 | 13 | C9orf64,DUS1L,ELP3,ELP4,LCMT2,METTL6,OSGEPL1,SEPHS2,THADA,TRMT10B,TRMT112,TRMT12,TRMT6 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 5.0e-07 | 900 | 976 | 46 | ADCY7,BAG5,BDNF,CALM2,CAMK2N1,CAMKK2,CAV1,CCND1,CCNO,EGFR,EGR1,ELP3,ELP4,GHRL,GRHL2,LRP8,MAD2L2,MAPKAP1,MLST8,MTOR,MUL1,NLRC5,NPRL2,PARK7,PDGFRA,PIK3CG,PKN1,PPM1F,PRKAG2,PSMD10,PTPRJ,RAC2,RASIP1,RELN,SAA1,SERPINB3,SFRP2,SLAMF8,SPRY1,SPTSSB,STK24,STK39,TEK,TLR3,TRIM27,TRPT1 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 5.0e-07 | 900 | 1881 | 71 | ABCG1,APCS,ARF6,ARNTL,BAG5,BDNF,CA2,CAV1,CCDC71L,CCN4,CCND1,CDK13,DPY30,EGFR,EID2B,ESRRA,FUOM,GBP1,GRHL2,H3-3B,H4C11,HAS2,HES4,HES7,IFITM1,IMPACT,JUNB,LHX1,LIF,LRP8,MAD2L2,MIB1,MTOR,MUL1,NAPEPLD,NCS1,NEDD4,NEGR1,NELFB,NRARP,PCID2,PDGFRA,PLAG1,PLXNA2,PRRX1,PSMB10,PSMB8,PSMB9,PSMD10,PTPRG,RAB11A,RELN,RNF41,ROR1,RYK,SERPINB3,SFRP2,SLAMF8,SS18L2,STK24,TFAP2B,TGIF2,TLR3,TMEM106B,TMEM131L,TRPS1,TSPO,TTL,WDR61,XDH,ZADH2 |
| GO_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 6.0e-07 | 900 | 1296 | 55 | ACTL8,AIMP2,ALDH1A3,ARNTL,B9D1,CA2,CAV1,CC2D2A,CCND1,CCNO,CEP63,CES1,CLDN1,CSTA,DEAF1,DLC1,DNPH1,EGFR,FERMT1,FOXF1,GRHL2,HES7,HHIP,IFT57,IFT74,KRT10,KRT75,LHX1,LIF,MIB1,MICAL2,MKKS,MTOR,MTSS1,NRARP,ORAI1,PCK2,PLEKHA4,PLXNA2,PSMB10,PSMB8,PSMB9,PSMD10,PTER,RASIP1,ROR1,RYK,SFRP2,SLC4A7,SPINK6,SPRY1,TBX2,TFAP2B,TMEM231,XDH |
| GO_REGULATION_OF_PEPTIDASE_ACTIVITY | 0.0e+00 | 6.0e-07 | 900 | 455 | 29 | AIFM1,BIRC3,CARD16,CASP1,CAV1,CSTA,DAP,DIABLO,DLC1,FIS1,IFI16,IFT57,MEFV,MUL1,PARK7,PCID2,PPM1F,PSMB8,PSMB9,RNF34,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPINK6,TFAP2B,TRIAP1,WFDC12,XDH |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 6.0e-07 | 900 | 542 | 32 | ARNTL,BAG5,CALM2,CAMK2N1,CAV1,DLC1,GBP1,LIF,MAPKAP1,MRAP,MTOR,MUC1,MUL1,NPRL2,NPRL3,PARK7,PSMD10,PTPRJ,RASA1,RASIP1,RNF34,SERPINB3,SFRP2,SPRY1,SRI,TAF9,TRIAP1,TXNDC12,WTIP,WWC1,WWC3,XDH |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 900 | 987 | 46 | AIFM1,ARNTL,BAG5,CAMKK2,CAV1,DAP,EDEM2,EGFR,EXOSC7,FMN2,GGA1,HNRNPA0,IFI16,LONP2,LPCAT1,MAD2L2,MEFV,MLST8,MTOR,MUL1,NEDD4,NPRL2,NPRL3,NUP37,PARK7,PCID2,PIK3CG,POLR2G,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,RASIP1,RNF139,RNF41,SCO1,SECISBP2,SEH1L,SF3B3,TAF9,TBRG4,TSPO,TYSND1,UBAC2,USP19 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 7.0e-07 | 900 | 1823 | 69 | ADCY7,AKTIP,APIP,BDNF,C1QTNF1,CALM2,CAMK2N1,CAMKK2,CAMTA1,CAV1,CCND1,CCNO,DLC1,EGFR,EGR1,ELP3,ELP4,GBP1,GHRL,GSDME,IGFBP4,IMPACT,ISCU,LIF,LPCAT1,LRP8,MAD2L2,MAPKAP1,MARCO,MLST8,MTOR,MUL1,NELFE,NLRC5,NPRL2,NUP37,PARK7,PDGFRA,PDK4,PIK3CG,PKN1,PPM1F,PRKAG2,PSMD10,PTPRJ,RAC2,RASIP1,RELN,RNF41,ROR1,RYK,SAA1,SEH1L,SERPINB3,SFRP2,SLAMF8,SPHK2,SPOCD1,SPRY1,STK24,STK39,TEK,TLR3,TMEM132D,TRIM27,TRPT1,WWC1,XDH,ZCCHC9 |
| GO_NCRNA_PROCESSING | 0.0e+00 | 7.0e-07 | 900 | 378 | 26 | C9orf64,DUS1L,ELP3,ELP4,EXOSC7,LCMT2,METTL15,METTL6,MRPS11,NHP2,NPM3,OSGEPL1,RPP38,RPUSD2,SEPHS2,SMAD1,THADA,TP53RK,TRMT10B,TRMT112,TRMT12,TRMT6,TRPT1,TSEN15,TSEN2,TUT1 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 7.0e-07 | 900 | 1026 | 47 | ALPK1,BIRC3,C1QTNF1,C1QTNF12,CALM2,CAMTA1,CARD16,CASP1,CAV1,EGFR,F2RL3,FIS1,GHRL,GSDME,IGFBP4,IL18R1,LIF,LURAP1,MARCO,MLST8,MRAP,MTOR,MUL1,NEDD4,NEK6,NELFE,NR3C2,P2RX5,PARK7,PDGFRA,PIK3CG,PKN1,PTPRJ,RAC2,RELN,ROR1,RXFP2,RYK,SAA1,SEH1L,SPHK2,STK39,TEK,TLR3,TMEM101,WWC1,XDH |
| GO_FATTY_ACID_METABOLIC_PROCESS | 0.0e+00 | 8.0e-07 | 900 | 380 | 26 | ACOXL,ACSL4,ACSL5,ASAH2B,CAV1,CES1,CYP1B1,CYP2D6,CYP4A11,FAAH2,GCDH,GGT5,GNPAT,LONP2,LYPLA1,MGLL,MMUT,MTOR,PCK2,PDK4,PRKAG2,PTGES2,SLC27A3,SLC27A5,TYSND1,ZADH2 |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 8.0e-07 | 900 | 1604 | 63 | ABCA6,ABCG1,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,C1QTNF12,CA2,CALM2,CAV1,CLCN5,CNNM3,COX17,COX8A,DNAJC19,F2RL3,GRIA1,ISCU,KCNG2,LONP2,MMGT1,MTOR,NCS1,NEDD4,ORAI1,P2RX5,PARK7,PARL,PDZD11,PEX12,PIK3CG,PKD1L1,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,RANGRF,RELN,S100A6,SLC1A7,SLC24A1,SLC25A15,SLC25A22,SLC25A43,SLC27A5,SLC37A4,SLC39A4,SLC3A1,SLC43A1,SLC4A7,SLC9A3,SLC9A5,SPHK2,SRI,STEAP1,STEAP2,STEAP4,STK39,TAP1,THADA,VAMP2 |
| GO_DNA_REPAIR | 0.0e+00 | 8.0e-07 | 900 | 551 | 32 | ALKBH2,BABAM2,CINP,COPS6,COPS7A,DDB2,EGFR,ENDOV,ERCC1,FANCE,FH,FMN2,H4C11,INO80C,MAD2L2,MCRS1,NSMCE1,NSMCE4A,PARK7,PARP10,PMS2P1,PMS2P6,POLR2G,POLR2I,RPAIN,RUVBL1,SLX1B,TTC5,USP45,WDR70,WRNIP1,ZSWIM7 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 9.0e-07 | 900 | 1318 | 55 | ADCY7,ALDH1A1,APCS,ARF6,ARNTL,BAG5,BCL3,C1QTNF1,CARD16,CCN4,CHID1,EGFR,F12,FERMT1,FUOM,GBP1,GHRL,GRHL2,H4C11,HES4,IL18R1,IL1RL1,IL20RB,MAD2L2,MEFV,MIB1,MTOR,MUL1,NLRC5,NRARP,NUTF2,PDCD1LG2,PDGFRA,PIK3CG,PLAU,PTGDR2,PTPRG,RYK,SFRP2,SLAMF8,SRGN,SRI,STK39,TBX2,TEK,TLR3,TMEM131L,TRIM27,TSPO,USP19,WDR61,WWC1,WWC3,XDH,ZNF706 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 9.0e-07 | 900 | 1994 | 73 | ADCK2,ADCY7,AKTIP,ALPK1,APIP,BDNF,C1QTNF1,CALM2,CAMK2N1,CAMKK2,CAV1,CCND1,CCNO,CDK13,CLK2,CSNK1G2,EGFR,EGR1,ELP3,ELP4,GBP1,GHRL,GSDME,IGFBP4,IMPACT,LIF,LRP8,MAD2L2,MAPKAP1,MARCO,MAST4,MLST8,MTOR,MUL1,NEK6,NELFE,NLK,NPRL2,PARK7,PDGFRA,PDK4,PIK3CG,PKN1,PKN2,PPM1F,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RAC2,RASA1,RASIP1,RELN,RNF41,ROR1,RYK,SAA1,SCYL3,SERPINB3,SFRP2,SPRY1,STK24,STK39,TBRG4,TEK,TLR3,TP53RK,TRIM27,TRPT1,WWC1,XDH |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 1.0e-06 | 900 | 526 | 31 | ACSL4,ADSL,AHCY,AIFM1,CBS,CCND1,DAP,EGFR,ERCC1,FIS1,GHRL,GNPAT,GSDMD,GSS,IFI16,IMPACT,MKKS,MTOR,NPRL2,NPRL3,OXCT1,P2RX5,PCK2,PDK4,PEMT,SEH1L,SFRP2,SLC39A4,STK24,TSPO,VCAM1 |
| GO_REGULATION_OF_INFLAMMATORY_RESPONSE | 0.0e+00 | 1.0e-06 | 900 | 387 | 26 | ADCY7,APCS,BIRC3,C1QTNF12,C2CD4A,CASP1,CCN4,CHID1,CYP19A1,EGFR,F12,FOXF1,GHRL,IL1RL1,IL20RB,MEFV,MGLL,NAPEPLD,PARK7,PIK3CG,SAA1,SBNO2,SLAMF8,STK39,TEK,TLR3 |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 1.0e-06 | 900 | 872 | 42 | ADCY7,BDNF,CALM2,CAMK2N1,CAMKK2,CAV1,CCND1,CCNO,EGFR,EGR1,ELP3,ELP4,GHRL,LRP8,MAPKAP1,MLST8,MTOR,MUL1,NLRC5,NPRL2,PARK7,PDGFRA,PIK3CG,PKN1,PPM1F,PRKAG2,PSMD10,PTPRJ,RAC2,RASIP1,RELN,SAA1,SERPINB3,SFRP2,SLAMF8,SPRY1,STK24,STK39,TEK,TLR3,TRIM27,TRPT1 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 1.1e-06 | 900 | 620 | 34 | ALDH1A1,B4GALT2,B4GALT7,C1QTNF1,C1QTNF12,CHID1,CLK2,COQ3,FAM3A,FUOM,G6PC3,GALE,GHRL,GUSB,GYG1,HAS2,IDUA,IGFBP4,INPP1,MDH2,MGAT2,MPI,MTOR,NANP,NUP37,PCK2,PDK4,PGP,PRKAG2,SEH1L,SLC37A4,SLC3A1,TFAP2B,YDJC |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 1.2e-06 | 900 | 1189 | 51 | APCS,BAG5,BCL3,BIRC3,CALM2,CAMK2N1,CARD16,CAV1,CSTA,EGFR,EIF4E2,FMN2,FRY,GBP1,GHRL,HDAC8,IFI16,IMPACT,LIF,MAD2L2,MTOR,PARK7,PARP10,PCID2,PKN1,PPM1F,PRKAG2,PSMD10,PTPRJ,RASIP1,RNF139,RNF34,SCO1,SERPINA1,SERPINB3,SERPINB4,SF3B3,SFRP2,SPHK2,SPINK6,SPRY1,TAF9,TFAP2B,TRIAP1,TRIM27,TSPO,UBAC2,USP19,USP4,WFDC12,XDH |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 1.2e-06 | 900 | 1935 | 71 | ABCG1,ACOXL,ADCY7,ADRA1D,ALDH1A1,ARNTL,C1QTNF1,C1QTNF12,CA2,CALM2,CAV1,CCN4,CCR4,CLDN1,CYP4A11,EGFR,EGR1,ERCC1,F2RL3,FBXO4,FH,FIS1,GHRL,GRIA1,H4C11,HAS2,HDAC8,IL18R1,IL20RB,ISCU,LPCAT1,MKKS,MTLN,NAPEPLD,NCS1,NHP2,OXCT1,P2RX5,PARK7,PCK2,PDGFRA,PDK4,PEMT,PIK3CG,PKN1,PNPLA4,PTGES2,RAB11A,RAC2,RANGRF,RMDN3,SAA1,SCO1,SH3BGRL3,SLAMF8,SLC24A1,SLC39A4,SLC4A7,SLC9A3,SLC9A5,SLX1B,SRI,STEAP1,STEAP2,STEAP4,STK39,TFAP2B,THADA,TMEM14C,TSPO,TXNDC12 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 1.3e-06 | 900 | 751 | 38 | ARNTL,BABAM2,BAG5,CAV1,EDEM2,EGFR,ERCC1,FBXO4,FMN2,GCH1,IMPACT,MAD2L2,MAPKAP1,MLST8,MTOR,MUC1,MUL1,NEK6,NSMCE1,NSMCE4A,NUP37,PARK7,PKN1,PRRX1,PSMD10,SEH1L,SERPINB3,SFRP2,STK24,TAF9,TLR3,TRIAP1,TXNDC12,UBAC2,USP19,WDR70,WRNIP1,XDH |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 2.1e-06 | 900 | 1175 | 50 | B9D1,BORCS8,CAV1,CBY1,CC2D2A,COL8A1,COX17,CYP1B1,DLC1,DNAH5,EGFR,EGR1,FOXF1,GHRL,GRHL2,HAS2,IFT57,IFT74,JUNB,LEMD3,LIF,LRG1,MIB1,MICAL2,MKKS,MMP19,MTOR,NEDD4,NPRL3,NRARP,OXCT1,PDGFRA,PIK3CG,PRRX1,RASA1,RASIP1,ROBO4,SFRP2,SMAD1,SNX17,SPHK2,SPRY1,SRI,TBX2,TEK,TFAP2B,TLR3,TMEM231,VCAM1,XDH |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 2.1e-06 | 900 | 1429 | 57 | ADCY7,AGAP3,AIFM1,AIMP2,ALDH1A1,BDNF,CALM2,CASP1,CAV1,CCND1,COX17,DAP,DIABLO,DLC1,DNAJC19,EGFR,EGR1,ELMOD2,FIS1,GCH1,GHRL,GRHL2,IFI16,IFT57,ISCU,LRP8,MAPKAP1,MEFV,MLST8,MMUT,MTOR,MUL1,NPRL2,NPRL3,ORAI1,PARK7,PDGFRA,PIK3CG,PKN1,PPM1F,PRKAG2,PSMD10,RASA1,RELN,RFK,RGS16,RIN1,SAA1,SERPINB3,SFRP2,STK24,STK39,SYDE2,TEK,TLR3,WRNIP1,XDH |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 0.0e+00 | 2.2e-06 | 900 | 1037 | 46 | ABCG1,ABHD17C,ABLIM3,ACSL4,ARF6,ARNTL,B9D1,BDNF,C1QTNF12,CARD16,CASP1,CCN4,EDEM2,EGFR,ENTR1,FBXO4,FERMT1,FIS1,GBP1,GHRL,GSDMD,HDAC8,IL1RL1,KCNG2,LEPROTL1,LIF,LYPLA1,MCRS1,MRAP,NUTF2,OXCT1,PARK7,PARL,PPM1F,RAB11A,RAC2,RANGRF,SAA1,SRGN,SRI,TFAP2B,TMEM231,TRIM27,UBAC2,UBL5,VAMP2 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 2.6e-06 | 900 | 1665 | 63 | ACSL4,ADGRE5,ADRA1D,AKAP7,ARNTL,BDNF,C1QTNF1,C1QTNF12,CA2,CAV1,CBY1,CCN4,CCND1,COLQ,CSNK1G2,CYP19A1,EGFR,EGR1,FERMT1,FRAT2,GHRL,GRIA1,IGFBP4,KCNG2,KLHL12,LHX1,LIF,LRP8,MAD2L2,MTOR,NCS1,NLK,NRARP,OXCT1,P2RX5,PARK7,PDZD11,PLEKHA4,PORCN,PSMB10,PSMB8,PSMB9,PSMD10,RAB11A,RANGRF,RELN,RIN1,ROR1,RUVBL1,RYK,SCG5,SERPINB3,SFRP2,SLC24A1,SNAP29,SRGN,SRI,TEK,TFAP2B,TMEM131L,UBAC2,VAMP2,WDR61 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 2.6e-06 | 900 | 1781 | 66 | ADCY7,AGAP3,AIFM1,AIMP2,AKTIP,ALDH1A1,ARF6,BDNF,CALM2,CARD16,CASP1,CAV1,CCND1,COX17,DAP,DIABLO,DLC1,DNAJC19,EGFR,EGR1,ELMOD2,FIS1,GCH1,GHRL,GRHL2,HDAC8,IFI16,IFT57,IL18R1,ISCU,LRP8,MAPKAP1,MEFV,MLST8,MMUT,MTOR,MUL1,NPRL2,NPRL3,ORAI1,PARK7,PDGFRA,PIK3CG,PKN1,PPM1F,PRKAG2,PSMD10,RASA1,RELN,RFK,RGS16,RIN1,RNF41,ROR1,SAA1,SERPINB3,SFRP2,STK24,STK39,STPG1,SYDE2,TEK,TLR3,TRIM27,WRNIP1,XDH |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 0.0e+00 | 2.7e-06 | 900 | 353 | 24 | AASDHPPT,ALDH1A3,APIP,ASAH2B,ASL,ATIC,CBS,CBSL,CYP2D6,CYP4A11,GCH1,GGT5,HAS2,MGLL,NANP,NAT8L,PARK7,PDK4,PRKAG2,PTGES2,PYCR2,PYCR3,SEPHS2,SLC27A5 |
| GO_COENZYME_METABOLIC_PROCESS | 0.0e+00 | 3.3e-06 | 900 | 254 | 20 | AASDHPPT,ACSL4,ACSL5,AHCY,APIP,ATIC,COQ3,COQ7,GCDH,GCH1,NADK2,NNMT,PANK4,PARP10,PCBD2,PDK4,PDZD11,PEMT,QDPR,RFK |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 3.3e-06 | 900 | 1267 | 52 | ABLIM3,ARF6,BRK1,CAMKK2,CDC14C,CDC42EP1,CDK13,CPLANE2,DLC1,ENTR1,EPS8,ERCC1,FBXO4,FIS1,H1-10,H3-3B,HDAC8,KIF9,LIF,MAD2L2,MKKS,MLST8,MTOR,MUC1,MUL1,NAA10,NEK6,NELFE,NPRL2,NPRL3,PARK7,PARL,PARP10,PCID2,PDGFRA,PPM1F,PRDM12,PSMD10,RAC2,RANGRF,RASA1,RNF41,SLX1B,SPHK2,TADA2A,TEK,TRIAP1,TRIM27,TSPO,UBL5,WDR61,WDR70 |
| GO_ELECTRON_TRANSPORT_CHAIN | 1.0e-07 | 3.5e-06 | 900 | 185 | 17 | COX8A,CYP19A1,ISCU,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,PTGES2,QDPR,SH3BGRL3,SLC25A22,STEAP4,UQCC3,UQCRFS1,XDH |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 1.0e-07 | 3.5e-06 | 900 | 1567 | 60 | ALPK1,AP1S1,APCS,BATF2,BCL3,BIRC3,CARD16,CASP1,CAV1,CCDC88B,CCR4,CHID1,CLDN1,EGR1,ELMOD2,EPG5,F12,FAM3A,GBP1,GCH1,GGT5,GSDMD,GSDME,HNRNPA0,IFI16,IFI44L,IFITM1,IRF2,JUNB,LRG1,LRP8,LSM14A,MARCO,MEFV,MUC1,MUL1,NLRC5,PDCD1LG2,PDZD11,PIK3CG,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RAET1E,SAA1,SBNO2,SDHAF4,SEH1L,SERPINB4,SLAMF8,SRPX,TLR3,TRIM27,TSPO,TTLL12,VCAM1,WFDC12,WRNIP1 |
| GO_OXIDATIVE_PHOSPHORYLATION | 1.0e-07 | 4.0e-06 | 900 | 144 | 15 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,COX8A,ISCU,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,UQCC3,UQCRFS1 |
| GO_ION_TRANSPORT | 1.0e-07 | 4.3e-06 | 900 | 1692 | 63 | ABCG1,ACSL4,ARMC1,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CA2,CALM2,CAV1,CLCN5,CNNM3,COX17,COX8A,CYP4A11,F2RL3,G6PC3,GRIA1,HBA2,ISCU,KCNG2,MMGT1,MTOR,NCS1,NEDD4,NKAIN2,ORAI1,P2RX5,PARK7,PARL,PDZD11,PIK3CG,PKD1L1,PRKAG2,RANGRF,RELN,S100A6,SCO1,SLC1A7,SLC24A1,SLC25A15,SLC25A22,SLC27A3,SLC27A5,SLC37A4,SLC39A4,SLC3A1,SLC43A1,SLC4A7,SLC9A3,SLC9A5,SPHK2,SRI,STEAP1,STEAP2,STEAP4,STK39,THADA,TRIAP1,TRIM27,TSPO,VAMP2 |
| GO_CHEMICAL_HOMEOSTASIS | 1.0e-07 | 4.3e-06 | 900 | 1207 | 50 | ABCG1,ACOXL,ADCY7,ADRA1D,C1QTNF1,C1QTNF12,CA2,CALM2,CAV1,CCN4,CCR4,CLDN1,CYP4A11,EGFR,F2RL3,FIS1,GHRL,GRIA1,HAS2,ISCU,LPCAT1,MTLN,NCS1,OXCT1,P2RX5,PARK7,PCK2,PDGFRA,PDK4,PIK3CG,PNPLA4,RAB11A,RANGRF,RMDN3,SAA1,SCO1,SLAMF8,SLC24A1,SLC39A4,SLC4A7,SLC9A3,SLC9A5,SRI,STEAP1,STEAP2,STEAP4,STK39,TFAP2B,THADA,TSPO |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 1.0e-07 | 4.6e-06 | 900 | 1930 | 69 | ABHD17C,ABLIM3,AGK,AP1S1,ARF6,ARNTL,BCL3,BDNF,CAV1,CC2D2A,COLQ,CPLANE2,DNAJC19,EDEM2,EGFR,ENTR1,FBXO4,FERMT1,FIS1,GBP1,GGA1,GNPAT,HDAC8,IFT57,IFT74,KIF17,LEPROTL1,LIF,LONP2,LRWD1,LTBP2,LYPLA1,MCRS1,MIPEP,MRAP,MTCH2,NCBP2,NECTIN3,NEDD4,NUP37,NUTF2,PARK7,PARL,PCID2,PDZD11,PEX12,PPM1F,RAB11A,RAC2,RANGRF,RELN,RHBDD1,RPAIN,SCG5,SEH1L,SNX17,SRGN,THOC7,TM9SF1,TMCO6,TMED3,TSPO,TYSND1,UBAC2,UBL5,USP4,VAMP2,ZDHHC4,ZNF593 |
| GO_RESPONSE_TO_CYTOKINE | 1.0e-07 | 4.6e-06 | 900 | 1210 | 50 | ACSL4,ATIC,BIRC3,BRWD1,CARD16,CASP1,CAV1,CCND1,CCR4,CLDN1,EGR1,EPS8,FOXF1,GBP1,GCH1,GGT5,GSDME,GSS,HAS2,HNRNPF,IFI16,IFITM1,IL18R1,IL1RL1,IL20RB,IMPDH2,IRF2,JUNB,LAPTM5,LIF,LRCH1,LRP8,LSM14A,MEFV,MKKS,MUC1,MUL1,NLRC5,PSMB10,PSMB8,PSMB9,PSMD10,SAA1,SBNO2,STK39,TAF9,TLR3,TTLL12,TXNDC17,VCAM1 |
| GO_COENZYME_BIOSYNTHETIC_PROCESS | 1.0e-07 | 4.6e-06 | 900 | 146 | 15 | ACSL4,ACSL5,ATIC,COQ3,COQ7,GCDH,GCH1,NADK2,NNMT,PANK4,PARP10,PCBD2,PDK4,QDPR,RFK |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1.0e-07 | 4.6e-06 | 900 | 1247 | 51 | ADCY7,AIMP2,AKTIP,ARNTL,BDNF,BIRC3,C1QTNF1,CALM2,CAMKK2,CAMTA1,CAV1,CCND1,DLC1,EGFR,EGR1,FBXO4,GHRL,GSDME,IGFBP4,LIF,LRP8,MAD2L2,MAPKAP1,MARCO,MLST8,MTOR,MUC1,MUL1,NELFE,PARK7,PDGFRA,PIK3CG,PKN1,PRDM12,PRKAG2,PSMD10,PTPRJ,RELN,ROR1,RYK,SAA1,SFRP2,SPHK2,STK24,STK39,TADA2A,TEK,TLR3,WDR61,WWC1,XDH |
| GO_REGULATION_OF_PHOSPHORYLATION | 1.0e-07 | 5.0e-06 | 900 | 1625 | 61 | ADCY7,AKTIP,APIP,BDNF,C1QTNF1,CALM2,CAMK2N1,CAMKK2,CAV1,CCND1,CCNO,EGFR,EGR1,ELP3,ELP4,GBP1,GHRL,GSDME,IGFBP4,IMPACT,ISCU,LIF,LRP8,MAD2L2,MAPKAP1,MARCO,MLST8,MTOR,MUL1,NELFE,NLRC5,NPRL2,NUP37,PARK7,PDGFRA,PIK3CG,PKN1,PPM1F,PRKAG2,PSMD10,PTPRJ,RAC2,RASIP1,RELN,RNF41,ROR1,RYK,SAA1,SEH1L,SERPINB3,SFRP2,SLAMF8,SPRY1,STK24,STK39,TEK,TLR3,TRIM27,TRPT1,WWC1,XDH |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 1.0e-07 | 6.3e-06 | 900 | 372 | 24 | ACSL4,ACSL5,AHCY,APIP,ARSG,B4GALT2,CBS,CBSL,CNDP2,ESD,GCDH,GGT5,GSS,HAGH,IDUA,ISCU,MICAL2,MMUT,NFU1,PARK7,PDK4,PDZD11,PEMT,SQOR |
| GO_CRISTAE_FORMATION | 1.0e-07 | 7.8e-06 | 900 | 34 | 8 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CHCHD6,MICOS13,UQCC3 |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 1.0e-07 | 7.7e-06 | 900 | 1160 | 48 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CALM2,CAV1,CLCN5,COX17,COX8A,F2RL3,GRIA1,ISCU,KCNG2,MMGT1,MTOR,NCS1,NEDD4,ORAI1,P2RX5,PARK7,PARL,PDZD11,PIK3CG,PKD1L1,PRKAG2,RANGRF,RELN,S100A6,SLC1A7,SLC24A1,SLC25A15,SLC25A22,SLC27A5,SLC37A4,SLC39A4,SLC3A1,SLC43A1,SLC4A7,SLC9A3,SLC9A5,SPHK2,SRI,STEAP2,STEAP4,STK39,THADA,VAMP2 |
| GO_INNER_MITOCHONDRIAL_MEMBRANE_ORGANIZATION | 1.0e-07 | 8.5e-06 | 900 | 47 | 9 | AGK,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CHCHD6,MICOS13,UQCC3 |
| GO_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 1.0e-07 | 8.3e-06 | 900 | 435 | 26 | ABCG1,ARV1,C1QTNF1,C1QTNF12,CAV1,CLK2,CLYBL,COQ3,EGR1,FAM3A,HAS2,IGFBP4,LONP2,MTOR,NUP37,PARK7,PDK4,PGP,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,SEH1L,SPHK2,TYSND1 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 2.0e-07 | 9.7e-06 | 900 | 410 | 25 | ADCY7,APCS,C1QTNF1,C1QTNF12,CARD16,CHID1,CYP19A1,F12,FAM3A,FOXF1,GHRL,IFI16,IL20RB,MEFV,MKKS,MUL1,NLRC5,PDGFRA,PLAU,RYK,SAA1,SERPINB4,SLAMF8,TEK,TTLL12 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 2.0e-07 | 1.0e-05 | 900 | 440 | 26 | ACOXL,AHCY,ALDH1A1,CBS,CYP4A11,ESD,GALE,GCAT,GCDH,GUSB,HAGH,HIBADH,IDUA,INPP1,LONP2,MGAT1,MMUT,MTOR,OXCT1,PCK2,PHYKPL,PPM1K,QDPR,SDSL,SNX17,TYSND1 |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 2.0e-07 | 1.0e-05 | 900 | 1174 | 48 | APCS,BAG5,BIRC3,CALM2,CAMK2N1,CARD16,CAV1,CSTA,CYP1B1,CYP2D6,DAP,FRY,IFI16,LRCH1,MAD2L2,MKKS,NEDD4,NLRC5,NPRL2,PARK7,PARP10,PCID2,PKN1,PPM1F,PRKAG2,PSMD10,PTPRJ,RASIP1,RNF34,SCG5,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPHK2,SPINK6,SPOCD1,SPRY1,SRI,STK39,TFAP2B,THADA,TMEM132D,TRIAP1,TRIM27,WFDC12,ZCCHC9,ZNF593 |
| GO_GLYCEROLIPID_METABOLIC_PROCESS | 2.0e-07 | 1.1e-05 | 900 | 414 | 25 | ACSL4,AGK,AWAT2,CAV1,CHPT1,CRLS1,GNPAT,INPP1,LPCAT1,MGLL,NAPEPLD,PCK2,PEMT,PGP,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PNPLA4,PTPMT1,PYURF,SLC27A5,TAMM41 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 2.0e-07 | 1.2e-05 | 900 | 1670 | 61 | ADCY7,ADGRE2,ALPK1,APCS,BIRC3,BRK1,CA2,CAV1,CCDC88B,COL17A1,CYP19A1,DPY30,EIF2B5,ELMOD2,EPG5,ESRRA,FAM3A,FOXF1,GBP1,H3-3B,H4C11,IFI16,IFITM1,IL18R1,IL1RL1,IL20RB,LAT2,LIF,LRCH1,LRP8,LSM14A,MAD2L2,MARCO,MILR1,MTOR,MUC1,MUL1,NLRC5,NRARP,PARK7,PCID2,PDCD1LG2,PKN1,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RAC2,RAET1E,RNF41,SERPINB4,SLAMF8,SPHK2,STK39,TLR3,TMEM131L,TRIM27,TTLL12,VCAM1,WDR61 |
| GO_ION_HOMEOSTASIS | 2.0e-07 | 1.3e-05 | 900 | 831 | 38 | ABCG1,ADRA1D,C1QTNF1,CA2,CALM2,CAV1,CCR4,CYP4A11,EGFR,F2RL3,FIS1,GHRL,GRIA1,ISCU,MTLN,NCS1,P2RX5,PDGFRA,PDK4,PIK3CG,RANGRF,RMDN3,SAA1,SCO1,SLAMF8,SLC24A1,SLC39A4,SLC4A7,SLC9A3,SLC9A5,SRI,STEAP1,STEAP2,STEAP4,STK39,TFAP2B,THADA,TSPO |
| GO_MACROMOLECULE_METHYLATION | 2.0e-07 | 1.3e-05 | 900 | 306 | 21 | CAMKMT,CMTR1,CMTR2,CSKMT,DPY30,DYDC1,GRHL2,LCMT2,METTL15,METTL6,NELFE,NTMT1,PRDM12,THADA,TRMT10B,TRMT112,TRMT12,TRMT6,TTLL12,WDR5B,WDR61 |
| GO_CHROMOSOME_ORGANIZATION | 2.0e-07 | 1.4e-05 | 900 | 1223 | 49 | AIFM1,BABAM2,BRWD1,C17orf49,COPS6,COPS7A,DDB2,DPY30,DYDC1,ERCC1,FBXO4,H1-10,H3-3B,H4C11,HDAC8,INO80C,LIF,LRWD1,MAD2L2,MCRS1,MUC1,NAA10,NEK6,NELFE,NHP2,NPM3,NTMT1,PARP10,PCGF1,PCID2,PKN1,PPM1F,PRDM12,RAB11A,RERE,RIOX2,RUVBL1,SATB2,SCMH1,SEH1L,SLX1B,SPHK2,STAG3L2,TADA2A,TAF9,TTLL12,WDR5B,WDR61,WDR70 |
| GO_PURINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 2.0e-07 | 1.4e-05 | 900 | 206 | 17 | ACSL4,ACSL5,ADCY7,ADSL,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,GCDH,IMPDH2,PANK4,PDK4,PRKAG2,SPHK2,UQCC3 |
| GO_PROTEIN_CATABOLIC_PROCESS | 3.0e-07 | 1.4e-05 | 900 | 938 | 41 | ABHD17C,AGAP3,ANAPC7,ARNTL,BAG5,CAV1,DCAF11,EDEM2,EGFR,FBXO39,FBXO4,FMN2,GGA1,LNX1,LONP2,LPCAT1,LYPLA1,MAD2L2,MTOR,MVB12A,NEDD4,PARK7,PJA1,PSMB10,PSMB8,PSMB9,PSMD10,RHBDD1,RNF139,RNF34,RNF41,RSPRY1,SCO1,SF3B3,TAF9,TRIM2,UBAC2,USP19,USP20,USP4,USP45 |
| GO_CANONICAL_WNT_SIGNALING_PATHWAY | 3.0e-07 | 1.5e-05 | 900 | 337 | 22 | ARNTL,CAV1,CSNK1G2,EGFR,EGR1,FERMT1,FRAT2,IGFBP4,KLHL12,MAD2L2,NRARP,PLEKHA4,PORCN,PSMB10,PSMB8,PSMB9,PSMD10,RUVBL1,RYK,SFRP2,TMEM131L,UBAC2 |
| GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 3.0e-07 | 1.6e-05 | 900 | 544 | 29 | ALDH1A3,CA2,CC2D2A,DEAF1,DLC1,EGFR,FOXF1,GRHL2,HHIP,IFT57,LHX1,LIF,MIB1,MICAL2,MKKS,MTOR,MTSS1,NRARP,PLEKHA4,PSMB10,PSMB8,PSMB9,PSMD10,RASIP1,ROR1,RYK,SFRP2,SPRY1,TBX2 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 3.0e-07 | 1.6e-05 | 900 | 942 | 41 | ANKRA2,ARF6,BAG5,BDNF,BRK1,CAV1,CDC42EP1,CLDN1,COLQ,DDB2,DLC1,ENTR1,EPS8,ERCC1,GHRL,H3-3B,HAS2,IMPACT,KIF9,MEFV,MKKS,MLST8,MTLN,MTOR,NPRL2,NPRL3,PARK7,PARP10,PPM1F,PTPRJ,RAC2,RANGRF,RASA1,RASIP1,SLX1B,SMPD2,SPHK2,TEK,TPBG,TRIM27,TRMT112 |
| GO_PROTEIN_MATURATION | 3.0e-07 | 1.7e-05 | 900 | 285 | 20 | BIRC3,CARD16,CASP1,CES1,CISD3,DHPS,F12,IFI16,LIPT1,LONP2,MIPEP,NAA10,NFU1,PLAU,PLGRKT,RHBDD1,RNF139,SCG5,SRGN,TYSND1 |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 3.0e-07 | 1.8e-05 | 900 | 984 | 42 | ABCG1,ABLIM3,ACSL4,ARF6,BORCS5,C1QTNF1,C1QTNF12,CA2,CALM2,CASP1,CAV1,COX17,CYP19A1,CYP4A11,EDEM2,EGFR,F2RL3,FERMT1,FIS1,GHRL,GSDMD,IL1RL1,MIB1,NCBP2,NCS1,NEDD4,NUTF2,ORAI1,OXCT1,P2RX5,PARK7,PTPRJ,RAC2,RELN,SAA1,SPHK2,SRI,STK39,TRIAP1,TSPO,UBL5,VAMP2 |
| GO_CELL_CELL_SIGNALING_BY_WNT | 4.0e-07 | 2.1e-05 | 900 | 521 | 28 | ARNTL,CAV1,CBY1,CCN4,CCND1,CSNK1G2,EGFR,EGR1,FERMT1,FRAT2,IGFBP4,KLHL12,MAD2L2,NLK,NRARP,PLEKHA4,PORCN,PSMB10,PSMB8,PSMB9,PSMD10,ROR1,RUVBL1,RYK,SFRP2,TMEM131L,UBAC2,WDR61 |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 4.0e-07 | 2.1e-05 | 900 | 990 | 42 | APCS,BATF2,BCL3,CA2,CCN4,CCR4,CDK13,DPY30,EGR1,ERCC1,ESRRA,H3-3B,H4C11,IFI16,IL18R1,IRF2BP2,JUNB,KRT75,LIF,MAD2L2,MTOR,NRARP,PCID2,PDGFRA,PKN1,PMS2P1,PMS2P6,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RNF41,SBNO2,SFRP2,SLAMF8,TEK,TLR3,TMEM131L,TMEM14C,VCAM1,WDR61 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 4.0e-07 | 2.2e-05 | 900 | 1825 | 64 | ADRA1D,ARF6,ARNTL,ATP5F1A,BCL3,BDNF,BIRC3,C1QTNF1,CA2,CASP1,CAV1,CCDC88B,CCN4,CCND1,CYP1B1,EGFR,EGR1,F12,FERMT1,FH,GCH1,GHRL,GSDMD,HAS2,IFI16,IFITM1,IL18R1,IL1RL1,IL20RB,IMPACT,LHX1,LIF,LRG1,LRP8,LSM14A,LURAP1,MAD2L2,MKKS,MTOR,MUL1,NEGR1,PARK7,PCID2,PEMT,PLAG1,PLXNA2,PPM1F,PTPRJ,RAB11A,RELN,ROR1,SAA1,SERPINB3,SFRP2,SMAD1,SPRY1,SS18L2,TBX2,TEK,TGIF2,TLR3,TMEM106B,TPBG,TSPO |
| GO_RIBONUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS | 4.0e-07 | 2.3e-05 | 900 | 69 | 10 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,IMPDH2,PRKAG2,SPHK2,UCK2,UQCC3 |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 4.0e-07 | 2.3e-05 | 900 | 463 | 26 | ACSL4,ACSL5,ADCY7,ADSL,AHCY,ATIC,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,DNPH1,GCDH,GDA,IMPDH2,MACROD1,NUP37,OARD1,PANK4,PDK4,PEMT,PRKAG2,SEH1L,SPHK2,UQCC3,XDH |
| GO_DNA_METABOLIC_PROCESS | 5.0e-07 | 2.4e-05 | 900 | 925 | 40 | AIFM1,ALKBH2,BABAM2,CBS,CINP,COPS6,COPS7A,DDB2,EGFR,ENDOV,ERCC1,FANCE,FBXO4,FH,FMN2,GRHL2,H1-10,H4C11,HDAC8,INO80C,LRWD1,MAD2L2,MCRS1,NHP2,NSMCE1,NSMCE4A,PARK7,PARP10,PMS2P1,PMS2P6,POLR2G,POLR2I,RPAIN,RUVBL1,SLX1B,TTC5,USP45,WDR70,WRNIP1,ZSWIM7 |
| GO_CELL_ACTIVATION | 5.0e-07 | 2.5e-05 | 900 | 1442 | 54 | ADGRE2,ADGRE5,APEH,BATF2,BCL3,C1QTNF1,CAV1,CCDC88B,CDK13,EGFR,EGR1,ERCC1,F2RL3,FIBP,FOXF1,GSDMD,GUSB,GYG1,IL18R1,IL1RL1,IL20RB,IMPDH2,IRF2BP2,LAT2,LPCAT1,LRG1,MAD2L2,MILR1,MTOR,NEDD4,NIT2,NRARP,PCID2,PDCD1LG2,PDGFRA,PIK3CG,PKN1,PLAU,PSMB10,PTGES2,PTPRJ,RAC2,RNF41,SAA1,SBNO2,SERPINA1,SERPINB3,SLAMF8,SNAP29,SPHK2,TLR3,TMEM131L,VAMP2,VCAM1 |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 5.0e-07 | 2.5e-05 | 900 | 622 | 31 | ARNTL,CAV1,CBY1,CCN4,CCND1,CSNK1G2,EGFR,EGR1,FERMT1,FRAT2,GHRL,IGFBP4,KLHL12,MAD2L2,NLK,NRARP,P2RX5,PLEKHA4,PORCN,PSMB10,PSMB8,PSMB9,PSMD10,RELN,ROR1,RUVBL1,RYK,SFRP2,TMEM131L,UBAC2,WDR61 |
| GO_ALCOHOL_METABOLIC_PROCESS | 5.0e-07 | 2.5e-05 | 900 | 377 | 23 | ABCG1,ALDH1A1,ALDH1A3,ARV1,ASAH2B,AWAT2,CES1,COQ3,CYP1B1,CYP2D6,DPAGT1,GCH1,INPP1,NAPEPLD,PARK7,PCBD2,PCK2,PGP,PNPLA4,QDPR,RDH5,SNX17,SPHK2 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 6.0e-07 | 2.8e-05 | 900 | 1410 | 53 | ABHD17C,AGAP3,AIFM1,ANAPC7,ARNTL,BAG5,CAV1,DCAF11,EDEM2,EGFR,EXOSC7,FBXO39,FBXO4,FMN2,GGA1,GUSB,HNRNPA0,IDUA,LNX1,LONP2,LPCAT1,LSM2,LYPLA1,MAD2L2,MTOR,MVB12A,NCBP2,NEDD4,PARK7,PCID2,PJA1,POLR2G,PSMB10,PSMB8,PSMB9,PSMD10,RHBDD1,RNF139,RNF34,RNF41,RSPRY1,SCO1,SECISBP2,SF3B3,TAF9,TBRG4,TRIM2,UBAC2,USP19,USP20,USP4,USP45,WDR61 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 6.0e-07 | 3.1e-05 | 900 | 831 | 37 | AIFM1,BAG5,CAMKK2,CAV1,DAP,EDEM2,EXOSC7,HNRNPA0,IFI16,LONP2,MEFV,MLST8,MTOR,MUL1,NEDD4,NPRL2,NPRL3,PARK7,PCID2,PIK3CG,POLR2G,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,RASIP1,RNF139,RNF41,SCO1,SECISBP2,TAF9,TBRG4,TSPO,TYSND1,UBAC2,USP19 |
| GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 6.0e-07 | 3.2e-05 | 900 | 763 | 35 | AIMP2,ATP5F1A,B4GALT7,CAMK2N1,CAV1,CGREF1,CYP1B1,DLC1,FBXO4,FERMT1,GHRL,GSDME,IFITM1,IFT57,IFT74,IL20RB,LIF,MTSS1,PARP10,PDCD1LG2,PEMT,PKN1,PTGDR2,PTPRJ,RNF139,RNF41,RXFP2,SFRP2,SPRY1,SRPX,TFAP2B,TMEM131L,TSPO,WDR13,XDH |
| GO_MRNA_PROCESSING | 6.0e-07 | 3.2e-05 | 900 | 503 | 27 | CDK13,CMTR1,CMTR2,CSTF1,GEMIN7,HNRNPA0,HNRNPF,HNRNPLL,LSM2,NCBP2,NELFE,PCBP1,POLR2G,POLR2I,RBMXL1,RPRD1A,RPUSD3,SF3B3,SF3B5,TBRG4,THOC7,TSEN15,TSEN2,TUT1,UBL5,USP4,ZCRB1 |
| GO_CELL_PROJECTION_ASSEMBLY | 7.0e-07 | 3.3e-05 | 900 | 567 | 29 | ABLIM3,ARF6,B9D1,BRK1,CAV1,CBY1,CC2D2A,CCDC113,CCNO,CDC14C,CDC42EP1,CEP63,CFAP298,CPLANE2,DNAAF2,DNAH5,ENTR1,EPS8,IFT57,IFT74,KIF17,LRRC6,MKKS,MTOR,MTSS1,RAB11A,RAC2,SNAP29,TMEM231 |
| GO_CELLULAR_KETONE_METABOLIC_PROCESS | 7.0e-07 | 3.6e-05 | 900 | 248 | 18 | CAV1,COQ3,COQ7,CYP19A1,EGR1,HAGH,KYAT3,LONP2,MTOR,OXCT1,PARK7,PDK4,PRKAG2,PSMB10,PSMB8,PSMB9,PSMD10,TYSND1 |
| GO_ATP_METABOLIC_PROCESS | 8.0e-07 | 3.9e-05 | 900 | 303 | 20 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,COX8A,ISCU,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,NUP37,PARK7,PRKAG2,SEH1L,SPHK2,TSPO,UQCC3,UQCRFS1 |
| GO_MRNA_METABOLIC_PROCESS | 8.0e-07 | 3.9e-05 | 900 | 840 | 37 | CDK13,CMTR1,CMTR2,CSTF1,EXOSC7,GEMIN7,HNRNPA0,HNRNPF,HNRNPLL,LSM2,MTOR,NCBP2,NELFE,PCBP1,PCID2,POLR2G,POLR2I,PSMB10,PSMB8,PSMB9,PSMD10,RBMXL1,RPRD1A,RPUSD3,SECISBP2,SF3B3,SF3B5,TBRG4,THOC7,TRMT6,TSEN15,TSEN2,TUT1,UBL5,USP4,WDR61,ZCRB1 |
| GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE | 8.0e-07 | 3.9e-05 | 900 | 250 | 18 | ADCY7,APCS,C1QTNF12,CHID1,CYP19A1,FAM3A,FOXF1,GHRL,IFI16,IL20RB,MEFV,MUL1,NLRC5,SAA1,SERPINB4,SLAMF8,TEK,TTLL12 |
| GO_NEUROGENESIS | 8.0e-07 | 4.0e-05 | 900 | 1625 | 58 | ACSL4,ARF6,ARNTL,BAG5,BDNF,BTBD3,CCR4,EGFR,EIF2B5,ELP3,ETV1,FRY,FUOM,GHRL,GSDME,HES4,HES7,HHIP,IMPACT,LHX1,LIF,LRP8,MDGA2,MIB1,MTOR,MUL1,NCAM2,NCS1,NEDD4,NEGR1,PLAG1,PLXNA2,PRDM12,PRDM8,PRRX1,PTPRG,RAB11A,RAC2,RELN,RERE,ROBO4,ROR1,RYK,S100A6,SATB2,SECISBP2,SFRP2,SLC4A7,SS18L2,STK24,TGIF2,TMEM106B,TPRN,TRAPPC4,TSPO,TTL,VCAM1,VXN |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 1.0e-06 | 4.9e-05 | 900 | 547 | 28 | ABCG1,ALDH1A1,ALDH1A3,ARV1,ASAH2B,AWAT2,CES1,COQ3,CYP19A1,CYP1B1,CYP2D6,CYP4A11,DPAGT1,GCH1,HAGH,INPP1,NAPEPLD,PARK7,PCBD2,PCK2,PGP,PNPLA4,PRKAG2,QDPR,RDH5,SLC27A5,SNX17,SPHK2 |
| GO_PEPTIDYL_LYSINE_MODIFICATION | 1.2e-06 | 5.6e-05 | 900 | 397 | 23 | CAMKMT,CSKMT,DHPS,DPY30,DYDC1,EGR1,LIF,LIPT1,MCRS1,MUC1,MUL1,NELFE,NUP37,PARK7,PRDM12,RUVBL1,SEH1L,SPHK2,TADA2A,TAF9,TTLL12,WDR5B,WDR61 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 1.2e-06 | 5.8e-05 | 900 | 1220 | 47 | ABLIM3,ARF6,BDNF,BRK1,CAMKK2,CAV1,CDC42EP1,CLDN1,DDB2,ENTR1,EPS8,ERCC1,FBXO4,FIS1,GHRL,HAS2,JMJD4,LIF,LRP8,MIB1,MLST8,MTLN,MTOR,MUC1,MUL1,NEGR1,NELFE,PARK7,PLXNA2,PPM1F,PRDM12,PTPRJ,RAB11A,RAC2,RASIP1,RELN,ROR1,SLX1B,SPHK2,SS18L2,TADA2A,TEK,TMEM106B,TPBG,TRIM27,UBL5,WDR61 |
| GO_MEMBRANE_LIPID_METABOLIC_PROCESS | 1.3e-06 | 6.0e-05 | 900 | 207 | 16 | AGK,ARV1,ASAH2B,CSNK1G2,CYP1B1,PEMT,PIGC,PIGO,PIGV,PYURF,SCCPDH,SGMS2,SMPD2,SPHK2,SPTSSB,SUMF2 |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1.3e-06 | 6.1e-05 | 900 | 823 | 36 | APCS,BAG5,BIRC3,CAMK2N1,CARD16,CAV1,CSTA,FRY,IFI16,LRCH1,MAD2L2,MKKS,NPRL2,PARK7,PCID2,PKN1,PPM1F,PRKAG2,PTPRJ,RASIP1,RNF34,SCG5,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPHK2,SPINK6,SPOCD1,SPRY1,TFAP2B,TMEM132D,TRIAP1,TRIM27,WFDC12,ZCCHC9 |
| GO_TUBE_MORPHOGENESIS | 1.3e-06 | 6.0e-05 | 900 | 928 | 39 | CAV1,CC2D2A,COL8A1,CYP1B1,DEAF1,DLC1,EGFR,FOXF1,GHRL,GRHL2,HAS2,HHIP,IFT57,JUNB,LEMD3,LHX1,LRG1,MIB1,MICAL2,MKKS,MMP19,MTSS1,NEDD4,NPRL3,NRARP,PDGFRA,PIK3CG,PRRX1,RASA1,RASIP1,ROBO4,SFRP2,SMAD1,SPRY1,TBX2,TEK,TFAP2B,TLR3,XDH |
| GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_IV_ASSEMBLY | 1.4e-06 | 6.5e-05 | 900 | 21 | 6 | COA4,COX14,COX17,PET117,SCO1,SMIM20 |
| GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 1.4e-06 | 6.3e-05 | 900 | 371 | 22 | ARNTL,CAV1,CBY1,CCN4,CSNK1G2,EGFR,EGR1,FERMT1,IGFBP4,KLHL12,MAD2L2,NLK,NRARP,PLEKHA4,PSMB10,PSMB8,PSMB9,PSMD10,RUVBL1,SFRP2,TMEM131L,UBAC2 |
| GO_IMMUNE_EFFECTOR_PROCESS | 1.5e-06 | 6.7e-05 | 900 | 1267 | 48 | ADGRE2,ADGRE5,APCS,APEH,BCL3,BIRC3,BRK1,CDK13,ELMOD2,ERCC1,FOXF1,GBP1,GSDMD,GUSB,GYG1,IFI16,IFI44L,IFITM1,IL18R1,IL20RB,IMPDH2,IRF2,LAT2,LPCAT1,LRG1,LSM14A,MAD2L2,MILR1,MTOR,MUL1,NIT2,NLRC5,PIK3CG,PKN1,PLAU,PTGES2,PTPRJ,RAC2,RAET1E,SBNO2,SERPINA1,SERPINB3,SERPINB4,SLAMF8,SNAP29,SPHK2,TLR3,VAMP2 |
| GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 1.5e-06 | 6.7e-05 | 900 | 261 | 18 | AGK,CHPT1,CRLS1,DPAGT1,GNPAT,LPCAT1,PEMT,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PTPMT1,PYURF,SGMS2,SPHK2,TAMM41 |
| GO_PHOSPHOLIPID_METABOLIC_PROCESS | 1.5e-06 | 6.6e-05 | 900 | 432 | 24 | AGK,CHPT1,CRLS1,DPAGT1,GNPAT,INPP1,LPCAT1,NAPEPLD,PDGFRA,PEMT,PGP,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PTPMT1,PYURF,SGMS2,SMPD2,SPHK2,TAMM41,TEK |
| GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | 1.5e-06 | 6.5e-05 | 900 | 861 | 37 | BCL3,CAV1,DPH6,EGFR,EIF2B5,EIF4E2,EXOSC7,FBXO4,H3-3B,H4C11,HNRNPA0,IMPACT,JMJD4,LSM14A,LSM14B,MIF4GD,MPV17L2,MTG1,MTOR,NCBP2,NUP37,PCID2,POLR2G,POLR2I,PSMB10,PSMB8,PSMB9,PSMD10,RNF139,RPUSD3,SECISBP2,SEH1L,SMAD1,TBRG4,WTIP,ZNF598,ZNF706 |
| GO_PROTEIN_COMPLEX_OLIGOMERIZATION | 1.5e-06 | 6.5e-05 | 900 | 493 | 26 | ADSL,ALDH1A3,APIP,BIRC3,BRK1,CBY1,CLDN1,CLYBL,DPAGT1,FARSA,FIS1,GBP1,GCH1,GRHPR,GSDMD,H4C11,IMPDH2,KCNG2,KRT10,SIGMAR1,STEAP4,TEK,TRAPPC11,TRIM27,TRPS1,TYSND1 |
| GO_CHROMATIN_ORGANIZATION | 1.6e-06 | 7.0e-05 | 900 | 795 | 35 | BABAM2,BRWD1,C17orf49,DDB2,DPY30,DYDC1,H1-10,H3-3B,H4C11,HDAC8,INO80C,LIF,LRWD1,MCRS1,MUC1,NELFE,NPM3,NTMT1,PARP10,PCGF1,PKN1,PPM1F,PRDM12,RERE,RIOX2,RUVBL1,SATB2,SCMH1,SPHK2,TADA2A,TAF9,TTLL12,WDR5B,WDR61,WDR70 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 1.6e-06 | 7.0e-05 | 900 | 289 | 19 | AIFM1,BAG5,BCL3,CAV1,CYP1B1,DIABLO,FIS1,GSDME,IFI16,MUC1,PARK7,PPM1F,PTPMT1,SFRP2,STK24,TAF9,TRIAP1,TXNDC12,ZNF385B |
| GO_RNA_METHYLATION | 1.6e-06 | 6.9e-05 | 900 | 79 | 10 | CMTR1,CMTR2,LCMT2,METTL15,METTL6,THADA,TRMT10B,TRMT112,TRMT12,TRMT6 |
| GO_LOCOMOTION | 1.7e-06 | 7.2e-05 | 900 | 1984 | 66 | ADGRE2,ARF6,ATP5F1A,BDNF,BRK1,CAV1,CCN4,CCR4,CLDN1,CYP19A1,CYP1B1,DLC1,DNAAF2,DNAH5,EFHC1,EGFR,ELP3,EPS8,ETV1,FERMT1,FOXF1,GCNT1,GHRL,HAS2,IFITM1,ITGBL1,LHX1,LRCH1,LRRC6,LURAP1,MIIP,MKKS,MTOR,PDGFRA,PIK3CG,PKN1,PKN2,PLAU,PLGRKT,PLXNA2,PPM1F,PTGDR2,PTPRG,PTPRJ,RAB11A,RAC2,RELN,RERE,RNF41,ROBO4,RYK,S100A2,SAA1,SATB2,SCYL3,SERPINB3,SFRP2,SLAMF8,STK24,STK39,TEK,TRIM27,TSPO,VCAM1,WWC1,ZNF502 |
| GO_CELLULAR_RESPIRATION | 1.8e-06 | 7.5e-05 | 900 | 187 | 15 | ADSL,COX8A,FH,ISCU,MDH2,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,SDHAF4,SLC25A22,UQCC3,UQCRFS1 |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 1.8e-06 | 7.8e-05 | 900 | 1200 | 46 | ALPK1,APCS,BATF2,BCL3,BIRC3,CASP1,CAV1,CCDC88B,CHID1,CLDN1,EGR1,ELMOD2,EPG5,F12,FAM3A,GBP1,GCH1,GSDMD,IFI16,IFI44L,IFITM1,IRF2,LRP8,LSM14A,MARCO,MEFV,MUC1,MUL1,NLRC5,PIK3CG,PSMB10,PSMB8,PSMB9,PSMD10,RAET1E,SAA1,SDHAF4,SEH1L,SERPINB4,SLAMF8,TLR3,TRIM27,TTLL12,VCAM1,WFDC12,WRNIP1 |
| GO_NUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS | 1.8e-06 | 7.6e-05 | 900 | 80 | 10 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,IMPDH2,PRKAG2,SPHK2,UCK2,UQCC3 |
| GO_ALPHA_AMINO_ACID_BIOSYNTHETIC_PROCESS | 1.9e-06 | 7.9e-05 | 900 | 63 | 9 | AASDHPPT,APIP,ASL,CBS,CBSL,PARK7,PYCR2,PYCR3,SEPHS2 |
| GO_REGULATION_OF_CELL_DEATH | 1.9e-06 | 7.9e-05 | 900 | 1748 | 60 | AIFM1,AIMP2,ALDH1A3,APIP,ARHGEF9,BABAM2,BAG5,BCL3,BDNF,BIRC3,CARD16,CASP1,CAV1,CCN4,CYP1B1,DAP,DIABLO,DLC1,EGFR,EGR1,EIF2B5,FIS1,FMN2,GHRL,GSDME,HBA2,HHIP,IFT57,IMPACT,LRP8,MTCH2,MTOR,MUC1,MUL1,PARK7,PCID2,PDK4,PIK3CG,PPM1F,PSMD10,PTPMT1,RASA1,RHBDD1,RNF34,RXFP2,SFRP2,SIGMAR1,SPHK2,SRPX,STPG1,TAF9,TEK,TFAP2B,TLR3,TP53AIP1,TRIAP1,TRIM2,TSPO,TXNDC12,XDH |
| GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS | 2.0e-06 | 8.3e-05 | 900 | 81 | 10 | AASDHPPT,APIP,ASL,CBS,CBSL,NAT8L,PARK7,PYCR2,PYCR3,SEPHS2 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 2.0e-06 | 8.1e-05 | 900 | 767 | 34 | ABCG1,ABLIM3,ACSL4,ARF6,ARNTL,C1QTNF12,CARD16,CASP1,CCN4,EDEM2,EGFR,FERMT1,FIS1,GBP1,GHRL,GSDMD,IL1RL1,KCNG2,LYPLA1,NUTF2,OXCT1,PARK7,PARL,PPM1F,RAB11A,RAC2,SAA1,SRGN,SRI,TFAP2B,TRIM27,UBAC2,UBL5,VAMP2 |
| GO_RESPONSE_TO_RADIATION | 2.1e-06 | 8.7e-05 | 900 | 441 | 24 | B4GALT2,BABAM2,BCL3,CAMKMT,CARD16,CCND1,CCR4,CLK2,DDB2,DEAF1,EGFR,EGR1,ERCC1,FBXO4,IFI16,IMPACT,JUNB,MTOR,NEDD4,RHBDD1,SFRP2,SLC24A1,TRIAP1,VCAM1 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 2.3e-06 | 9.4e-05 | 900 | 603 | 29 | AIFM1,BAG5,BCL3,BDNF,CASP1,CAV1,CYP1B1,DAP,DIABLO,FIS1,GSDME,IFI16,MUC1,MUL1,PARK7,PPM1F,PSMD10,PTPMT1,RNF34,RNF41,SFRP2,SRGN,SRPX,STK24,TAF9,TLR3,TRIAP1,TXNDC12,ZNF385B |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 2.3e-06 | 9.4e-05 | 900 | 879 | 37 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CALM2,CAV1,CLCN5,COX17,COX8A,F2RL3,GRIA1,ISCU,KCNG2,MMGT1,NCS1,NEDD4,ORAI1,P2RX5,PARK7,PARL,PIK3CG,PKD1L1,RANGRF,RELN,SLC24A1,SLC25A15,SLC39A4,SLC9A3,SLC9A5,SPHK2,SRI,STEAP2,STEAP4,STK39,THADA,VAMP2 |
| GO_CYTOKINE_PRODUCTION | 2.3e-06 | 9.4e-05 | 900 | 808 | 35 | ADCY7,BCL3,BIRC3,CARD16,CASP1,CCDC88B,CCN4,CHID1,CYP1B1,EGR1,FERMT1,GBP1,GHRL,GSDMD,IFI16,IL18R1,IL1RL1,IL20RB,LSM14A,LURAP1,MEFV,MUL1,NLRC5,NUTF2,PARK7,PDCD1LG2,PIK3CG,PTPRJ,SAA1,SEH1L,SPHK2,SRGN,TLR3,TRIM27,TSPO |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 2.3e-06 | 9.2e-05 | 900 | 537 | 27 | ABHD17C,ABLIM3,ARF6,BDNF,EDEM2,EGFR,ENTR1,FBXO4,FERMT1,FIS1,GBP1,HDAC8,LEPROTL1,LIF,LYPLA1,MCRS1,MRAP,NUTF2,PARK7,PARL,PPM1F,RAB11A,RAC2,RANGRF,UBAC2,UBL5,VAMP2 |
| GO_NEURON_DIFFERENTIATION | 2.4e-06 | 9.5e-05 | 900 | 1365 | 50 | ACSL4,ARF6,BAG5,BDNF,BTBD3,EGFR,ETV1,FRY,FUOM,GHRL,GSDME,HES4,IMPACT,LHX1,LIF,LRP8,MDGA2,MIB1,MTOR,MUL1,NCAM2,NCS1,NEDD4,NEGR1,PLXNA2,PRDM12,PRRX1,PTPRG,RAB11A,RAC2,RELN,RERE,ROBO4,ROR1,RYK,S100A6,SATB2,SECISBP2,SFRP2,SLC4A7,SS18L2,STK24,TGIF2,TMEM106B,TPRN,TRAPPC4,TSPO,TTL,VCAM1,VXN |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 2.4e-06 | 9.6e-05 | 900 | 1721 | 59 | ABCG1,ADCY7,AIFM1,ARF6,ARNTL,BDNF,C1QTNF12,CA2,CAV1,CCND1,CLDN1,CRLS1,EGFR,EGR1,EIF2B5,ESRRA,FERMT1,FIBP,FIS1,GCNT1,GGT5,GHRL,H3-3B,HAS2,HHIP,HNRNPF,IMPACT,JUNB,LEMD3,LHX1,LRG1,LTBP2,MKKS,MMP19,MTOR,NCBP2,NEDD4,NLK,NR3C2,OXCT1,PARK7,PCK2,PDGFRA,PDK4,PIK3CG,PKD1L1,POLR2G,POLR2I,QDPR,RXFP2,SFRP2,SMAD1,SPRY1,STEAP2,TEK,TFAP2B,TSPO,VAMP2,VCAM1 |
| GO_GROWTH | 2.5e-06 | 9.8e-05 | 900 | 990 | 40 | BDNF,BNC2,CHPT1,COLQ,CYP19A1,DNPH1,EBAG9,EGFR,ENOX2,ERCC1,EXTL3,GHRL,GRHL2,H3-3B,IGFBP4,IMPACT,LHX1,MAD2L2,MCTS1,MKKS,MTOR,MUL1,NAIF1,NINJ1,PLAG1,PPM1F,PSMD10,PTPRJ,RAB11A,RUVBL1,RYK,SFRP2,SPHK2,SPRY1,ST7L,TAF9,TBX2,TTL,WWC1,WWC3 |
| GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS | 2.5e-06 | 9.8e-05 | 900 | 145 | 13 | AGK,ASAH2B,CSNK1G2,PEMT,PIGC,PIGO,PIGV,PYURF,SCCPDH,SGMS2,SMPD2,SPHK2,SPTSSB |
| GO_RIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS | 2.5e-06 | 9.9e-05 | 900 | 83 | 10 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,IMPDH2,PRKAG2,SPHK2,UCK2,UQCC3 |
| GO_CYTOCHROME_COMPLEX_ASSEMBLY | 2.6e-06 | 9.9e-05 | 900 | 35 | 7 | COA4,COX14,COX17,PET117,SCO1,SMIM20,UQCC3 |
| GO_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS | 2.6e-06 | 1.0e-04 | 900 | 169 | 14 | ACSL4,ACSL5,AWAT2,CYP1B1,CYP2D6,CYP4A11,FAAH2,GCDH,GGT5,MGLL,OXCT1,PTGES2,SLC27A5,ZADH2 |
| GO_ORGANIC_ACID_CATABOLIC_PROCESS | 2.6e-06 | 9.9e-05 | 900 | 271 | 18 | ACOXL,AHCY,CBS,CYP4A11,GCAT,GCDH,GUSB,HIBADH,IDUA,LONP2,MMUT,MTOR,PCK2,PHYKPL,PPM1K,QDPR,SDSL,TYSND1 |
| GO_PATTERN_SPECIFICATION_PROCESS | 2.6e-06 | 9.9e-05 | 900 | 446 | 24 | CC2D2A,DNAH5,FOXF1,HES4,HES7,HHIP,HOXC4,IFT57,IFT74,LHX1,LRRC6,MIB1,MICAL2,MKKS,NRARP,PKD1L1,PLXNA2,RELN,SATB2,SCMH1,SFRP2,SMAD1,SPRY1,TBX2 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 2.6e-06 | 9.9e-05 | 900 | 777 | 34 | ALPK1,APCS,BIRC3,CARD16,CAV1,ELMOD2,EPG5,FAM3A,IFI16,IFITM1,LRP8,LSM14A,MARCO,MUC1,MUL1,NELFB,NELFE,NLRC5,PARP10,PKN2,POLR2G,POLR2I,PSMB10,PSMB8,PSMB9,PSMD10,PTGDR2,RAET1E,SERPINB4,SLAMF8,TLR3,TRIM27,TTLL12,ZNF502 |
| GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS | 3.1e-06 | 1.2e-04 | 900 | 360 | 21 | BAG5,BIRC3,CAMK2N1,CARD16,CSTA,IFI16,PARK7,PCID2,RNF34,SCO1,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPINK6,TAF9,TFAP2B,TRIAP1,UBAC2,USP19,WFDC12 |
| GO_REGULATION_OF_GROWTH | 3.1e-06 | 1.2e-04 | 900 | 680 | 31 | BDNF,CHPT1,COLQ,DNPH1,EBAG9,EGFR,ENOX2,EXTL3,GHRL,H3-3B,IGFBP4,MAD2L2,MCTS1,MKKS,MTOR,MUL1,NAIF1,PPM1F,PSMD10,PTPRJ,RAB11A,RUVBL1,RYK,SFRP2,SPHK2,ST7L,TAF9,TBX2,TTL,WWC1,WWC3 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 3.4e-06 | 1.3e-04 | 900 | 362 | 21 | AIFM1,CASP1,CAV1,DAP,DIABLO,DLC1,EDEM2,F12,FIS1,IFI16,IFT57,MEFV,MUL1,PLGRKT,PPM1F,PSMD10,RHBDD1,RNF139,SERPINB3,SFRP2,XDH |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 3.6e-06 | 1.3e-04 | 900 | 860 | 36 | CAV1,CCND1,CGGBP1,DEAF1,E2F5,EGR1,ESRRA,FOXF1,HDAC8,HES4,HES7,IFI16,IMPACT,IRF2,IRF2BP1,IRF2BPL,JUNB,MAD2L2,NEDD4,NELFB,NELFE,NRARP,PCGF1,PRRX1,PSMD10,SATB2,TBX2,TFAP2B,TGIF2,TRIM27,TRPS1,WWC1,WWC3,ZBTB5,ZNF501,ZNF564 |
| GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 3.7e-06 | 1.4e-04 | 900 | 278 | 18 | ADSL,COX8A,FH,GYG1,ISCU,MDH2,MTOR,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,PRKAG2,SDHAF4,SLC25A22,UQCC3,UQCRFS1 |
| GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS | 3.8e-06 | 1.4e-04 | 900 | 251 | 17 | ACSL4,AGK,CHPT1,CRLS1,GNPAT,LPCAT1,PCK2,PEMT,PGS1,PIGC,PIGO,PIGV,PIK3CG,PLEKHA4,PTPMT1,PYURF,TAMM41 |
| GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS | 3.8e-06 | 1.4e-04 | 900 | 128 | 12 | AHCY,ATIC,DNPH1,GUSB,IMPDH2,LCMT2,MACROD1,OARD1,PEMT,PUDP,TRMT12,UCK2 |
| GO_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 3.8e-06 | 1.4e-04 | 900 | 199 | 15 | AIFM1,CASP1,CAV1,DAP,DIABLO,DLC1,FIS1,IFI16,IFT57,MEFV,MUL1,PPM1F,SERPINB3,SFRP2,XDH |
| GO_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS | 3.9e-06 | 1.4e-04 | 900 | 107 | 11 | ACSL4,ACSL5,ASAH2B,CYP1B1,CYP2D6,CYP4A11,FAAH2,MGLL,PTGES2,SLC27A3,SLC27A5 |
| GO_ATP_BIOSYNTHETIC_PROCESS | 4.0e-06 | 1.4e-04 | 900 | 52 | 8 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,PRKAG2,SPHK2,UQCC3 |
| GO_REGULATION_OF_HORMONE_LEVELS | 4.4e-06 | 1.6e-04 | 900 | 524 | 26 | ACSL4,ALDH1A1,ALDH1A3,ARNTL,AWAT2,C1QTNF1,C1QTNF12,CES1,COLQ,CYP19A1,CYP1B1,CYP2D6,EGFR,EGR1,GHRL,KCNG2,LIF,OXCT1,PARK7,PDGFRA,PNPLA4,RDH5,SCG5,SRI,TFAP2B,TSPO |
| GO_RESPIRATORY_CHAIN_COMPLEX_IV_ASSEMBLY | 4.4e-06 | 1.6e-04 | 900 | 25 | 6 | COA4,COX14,COX17,PET117,SCO1,SMIM20 |
| GO_ORGANELLE_ASSEMBLY | 4.8e-06 | 1.7e-04 | 900 | 835 | 35 | ABLIM3,B9D1,CBY1,CC2D2A,CCDC113,CCDC136,CCNO,CDC14C,CEP63,CFAP298,CPLANE2,DNAAF2,DNAH5,EMC6,ENTR1,IFT57,IFT74,KIF17,KIF9,LRRC6,LSM14A,MKKS,MPV17L2,MRPL20,MRPS11,MVB12A,NEK6,NPRL2,NPRL3,PDGFRA,RAB11A,SAC3D1,SNAP29,SRPX,TMEM231 |
| GO_REGULATION_OF_CELL_ADHESION | 4.9e-06 | 1.7e-04 | 900 | 695 | 31 | ABI3BP,C1QTNF1,C2CD4A,CAV1,CCDC88B,COL8A1,CYP1B1,DLC1,FERMT1,FOXF1,GBP1,HAS2,IFT74,IL20RB,MAD2L2,MUC1,NINJ1,NRARP,PDCD1LG2,PIK3CG,PLAU,PLXNA2,PPM1F,PTPRJ,RAC2,RASA1,SAA1,SFRP2,TEK,TMEM131L,VCAM1 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 5.0e-06 | 1.8e-04 | 900 | 561 | 27 | ADCY7,AIFM1,ALG2,ATIC,CA2,CALM2,CAV1,CCND1,CLDN1,CPNE8,CYP1B1,EGFR,EIF2B5,ERCC1,FIS1,GCH1,GSS,HBA2,IMPACT,JUNB,NEDD4,PARK7,QDPR,SIGMAR1,STK24,TSPO,VCAM1 |
| GO_RESPONSE_TO_DRUG | 5.5e-06 | 1.9e-04 | 900 | 1061 | 41 | ADCY7,AIFM1,CA2,CAV1,CCND1,CCNO,CLDN1,CRLS1,CYP1B1,CYP2D6,EGFR,EGR1,EPS8,GHRL,GNPAT,HBA2,IMPACT,JUNB,LRP8,MTOR,NNMT,OXCT1,P2RX5,PARK7,PCK2,PEMT,PPM1F,QDPR,SFRP2,SIGMAR1,SLAMF8,SLC1A7,SLC25A15,SLC25A22,SPHK2,STK24,STK39,TFAP2B,TLR3,TSPO,VCAM1 |
| GO_TRNA_METHYLATION | 5.6e-06 | 2.0e-04 | 900 | 39 | 7 | LCMT2,METTL6,THADA,TRMT10B,TRMT112,TRMT12,TRMT6 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 5.7e-06 | 2.0e-04 | 900 | 232 | 16 | AIMP2,BAG5,BIRC3,CAV1,EGR1,FBXO4,HDAC8,MAD2L2,MTOR,MUL1,PARK7,PARP10,PSMD10,TSPO,USP4,WDR70 |
| GO_LYSOSOME_LOCALIZATION | 5.9e-06 | 2.0e-04 | 900 | 72 | 9 | ADGRE2,BORCS5,FOXF1,LAT2,MILR1,PIK3CG,RAC2,SPHK2,TMEM106B |
| GO_TISSUE_MORPHOGENESIS | 6.4e-06 | 2.2e-04 | 900 | 670 | 30 | ALDH1A3,CA2,CC2D2A,DEAF1,DLC1,EGFR,FOXF1,GCNT1,GRHL2,HHIP,IFT57,LHX1,LIF,MIB1,MICAL2,MKKS,MTOR,MTSS1,NRARP,PLEKHA4,PSMB10,PSMB8,PSMB9,PSMD10,RASIP1,ROR1,RYK,SFRP2,SPRY1,TBX2 |
| GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION | 6.6e-06 | 2.3e-04 | 900 | 135 | 12 | AGK,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CHCHD6,MICOS13,MUL1,NAIF1,STPG1,UQCC3 |
| GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 6.6e-06 | 2.3e-04 | 900 | 348 | 20 | ABLIM3,ADGRE2,ARV1,BORCS5,EDEM2,FERMT1,FIS1,FOXF1,NCBP2,NEDD4,NUTF2,PARK7,PARL,RAC2,RNF139,SPHK2,UBAC2,UBL5,VAMP2,WWC1 |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 6.7e-06 | 2.3e-04 | 900 | 1146 | 43 | ADCY7,AKTIP,BDNF,C1QTNF1,CALM2,CAMKK2,CAMTA1,CAV1,CCND1,DLC1,EGFR,EGR1,GHRL,GSDME,IGFBP4,ISCU,LIF,LRP8,MAD2L2,MAPKAP1,MARCO,MLST8,MTOR,MUL1,NELFE,PARK7,PDGFRA,PIK3CG,PKN1,PRKAG2,PSMD10,PTPRJ,RELN,ROR1,RYK,SAA1,SFRP2,STK24,STK39,TEK,TLR3,WWC1,XDH |
| GO_PHOSPHATIDYLGLYCEROL_BIOSYNTHETIC_PROCESS | 6.9e-06 | 2.3e-04 | 900 | 8 | 4 | CRLS1,PGS1,PTPMT1,TAMM41 |
| GO_MONOSACCHARIDE_METABOLIC_PROCESS | 7.3e-06 | 2.5e-04 | 900 | 292 | 18 | ALDH1A1,C1QTNF1,C1QTNF12,CLK2,FAM3A,FUOM,G6PC3,GALE,GHRL,IGFBP4,MDH2,MPI,MTOR,PCK2,PDK4,PGP,SLC37A4,TFAP2B |
| GO_CILIUM_ORGANIZATION | 7.4e-06 | 2.5e-04 | 900 | 381 | 21 | ABLIM3,B9D1,CBY1,CC2D2A,CCDC113,CCNO,CDC14C,CEP63,CFAP298,CPLANE2,DNAAF2,DNAH5,ENTR1,IFT57,IFT74,KIF17,LRRC6,MKKS,RAB11A,SNAP29,TMEM231 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 7.5e-06 | 2.5e-04 | 900 | 1151 | 43 | ABLIM3,AGK,AP1S1,ARF6,ARNTL,DNAJC19,EDEM2,FERMT1,FIS1,GGA1,GNPAT,IFT57,IFT74,KIF17,LONP2,LTBP2,MIPEP,NCBP2,NEDD4,NUP37,NUTF2,PARK7,PARL,PCID2,PEX12,RAB11A,RAC2,RANGRF,RHBDD1,RPAIN,SCG5,SEH1L,SNX17,THOC7,TMCO6,TMED3,TSPO,TYSND1,UBAC2,UBL5,VAMP2,ZDHHC4,ZNF593 |
| GO_RESPIRATORY_ELECTRON_TRANSPORT_CHAIN | 7.9e-06 | 2.6e-04 | 900 | 115 | 11 | COX8A,ISCU,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,SLC25A22,UQCC3,UQCRFS1 |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 8.0e-06 | 2.7e-04 | 900 | 1116 | 42 | ADCY7,ADGRE2,ALPK1,APCS,BIRC3,BRK1,CAV1,COL17A1,EIF2B5,EPG5,FAM3A,FOXF1,GBP1,IFI16,IFITM1,IL18R1,IL1RL1,IL20RB,LAT2,LRP8,LSM14A,MAD2L2,MARCO,MUC1,MUL1,NLRC5,PARK7,PKN1,PSMB10,PSMB8,PSMB9,PSMD10,PTPRJ,RAC2,RAET1E,SERPINB4,SLAMF8,SPHK2,TLR3,TRIM27,TTLL12,VCAM1 |
| GO_CELLULAR_LIPID_CATABOLIC_PROCESS | 8.2e-06 | 2.7e-04 | 900 | 212 | 15 | ACOXL,ASAH2B,CYP1B1,CYP4A11,GCDH,LONP2,MGLL,MMUT,MTOR,NAPEPLD,PCK2,PIK3CG,PNPLA4,SMPD2,TYSND1 |
| GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 8.3e-06 | 2.7e-04 | 900 | 478 | 24 | AGAP3,ANAPC7,ARNTL,BAG5,CAV1,DCAF11,EDEM2,FBXO39,FBXO4,NEDD4,PARK7,PSMB10,PSMB8,PSMB9,PSMD10,RHBDD1,RNF139,RNF34,RNF41,SCO1,TAF9,TRIM2,UBAC2,USP19 |
| GO_INNATE_IMMUNE_RESPONSE | 8.4e-06 | 2.8e-04 | 900 | 1005 | 39 | ALPK1,APCS,BIRC3,CASP1,CAV1,CHID1,CLDN1,EGR1,EPG5,F12,FAM3A,GBP1,GCH1,GSDMD,IFI16,IFITM1,IRF2,LRP8,LSM14A,MARCO,MEFV,MUC1,MUL1,NLRC5,PIK3CG,PSMB10,PSMB8,PSMB9,PSMD10,RAET1E,SAA1,SDHAF4,SERPINB4,SLAMF8,TLR3,TRIM27,TTLL12,VCAM1,WRNIP1 |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 8.9e-06 | 2.9e-04 | 900 | 860 | 35 | ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CALM2,CAV1,CLCN5,COX17,COX8A,F2RL3,ISCU,KCNG2,MMGT1,MTOR,NCS1,NEDD4,ORAI1,PARK7,PARL,PIK3CG,PKD1L1,RANGRF,SLC24A1,SLC37A4,SLC39A4,SLC9A3,SLC9A5,SPHK2,SRI,STEAP2,STEAP4,STK39,THADA,VAMP2 |
| GO_REGULATION_OF_SECRETION | 9.0e-06 | 2.9e-04 | 900 | 824 | 34 | ABCG1,ACSL4,ADGRE2,ARF6,ARNTL,C1QTNF1,C1QTNF12,CARD16,CASP1,CCN4,CPLANE2,CYP19A1,CYP4A11,EGFR,FERMT1,FOXF1,GBP1,GHRL,GSDMD,IL1RL1,KCNG2,LIF,NCS1,OXCT1,RAC2,SAA1,SCG5,SPHK2,SRGN,SRI,STK39,TFAP2B,TRIM27,VAMP2 |
| GO_TUBE_DEVELOPMENT | 9.1e-06 | 2.9e-04 | 900 | 1122 | 42 | AIMP2,CAV1,CC2D2A,COL8A1,CYP1B1,DEAF1,DLC1,EGFR,FOXF1,GHRL,GRHL2,HAS2,HHIP,IFT57,JUNB,LEMD3,LHX1,LIF,LRG1,MIB1,MICAL2,MKKS,MMP19,MTSS1,NEDD4,NPRL3,NRARP,PDGFRA,PIK3CG,PLXNA2,PRRX1,RASA1,RASIP1,ROBO4,SFRP2,SMAD1,SPRY1,TBX2,TEK,TFAP2B,TLR3,XDH |
| GO_CELL_MOTILITY | 9.2e-06 | 2.9e-04 | 900 | 1758 | 58 | ADGRE2,ARF6,ATP5F1A,BRK1,CAV1,CCN4,CCR4,CLDN1,CYP19A1,CYP1B1,DLC1,DNAAF2,DNAH5,EFHC1,EGFR,ELP3,EPS8,FERMT1,FOXF1,GCNT1,HAS2,IFITM1,ITGBL1,LHX1,LRCH1,LRRC6,LURAP1,MIIP,MKKS,MTOR,PDGFRA,PIK3CG,PKN1,PKN2,PLAU,PLXNA2,PPM1F,PTPRG,PTPRJ,RAB11A,RAC2,RELN,RERE,RNF41,ROBO4,S100A2,SAA1,SATB2,SCYL3,SERPINB3,SFRP2,SLAMF8,STK24,STK39,TEK,TSPO,VCAM1,WWC1 |
| GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 9.2e-06 | 2.9e-04 | 900 | 481 | 24 | APCS,CYP19A1,FAM3A,FOXF1,GBP1,H4C11,IFI16,IL1RL1,IL20RB,LRCH1,MILR1,MUL1,NLRC5,NRARP,PDCD1LG2,PKN1,PTPRJ,SERPINB4,SLAMF8,TLR3,TMEM131L,TRIM27,TTLL12,WDR61 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 9.3e-06 | 3.0e-04 | 900 | 1047 | 40 | ABCG1,APCS,ARF6,ARNTL,BAG5,BDNF,CAV1,CCN4,CCND1,CDK13,EGFR,EID2B,FERMT1,FUOM,GBP1,GHRL,GRHL2,H4C11,HES4,MAD2L2,MIB1,MUL1,NELFB,NRARP,PTPRG,RYK,SFRP2,SRGN,TBX2,TEK,TLR3,TMEM131L,TSPO,USP19,WDR61,WWC1,WWC3,XDH,ZADH2,ZNF706 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 9.6e-06 | 3.1e-04 | 900 | 1163 | 43 | BDNF,BRWD1,CDC42EP1,CYP1B1,DLC1,EPS8,FIS1,GBP1,GHRL,HAS2,LHX1,LIF,LRG1,LRP8,MTOR,MUL1,NEDD4,NRARP,PKN1,PLEKHA4,PLXNA2,PSMB10,PSMB8,PSMB9,PSMD10,RAB11A,RAC2,RASA1,RELN,ROR1,RYK,SFRP2,SMAD1,SPRY1,SS18L2,TBX2,TEK,TGIF2,TLR3,TTL,WTIP,XDH,ZMYM6 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 9.7e-06 | 3.1e-04 | 900 | 974 | 38 | ARNTL,BIRC3,CCDC136,CCND1,CNBD2,CREB3L4,CYP19A1,DEAF1,DMRTA1,DNAJC19,EGFR,EIF2B5,ERCC1,FMN2,GGT5,GHRL,GRHL2,H3-3B,HSF2BP,IRF2BPL,JUNB,LHX1,LIF,LRRC6,MKKS,MMP19,MTOR,NECTIN3,PDGFRA,PLAG1,RHBDD1,RUVBL1,RXFP2,SCMH1,SFRP2,SPA17,TLR3,TRIM27 |
| GO_RESPONSE_TO_STARVATION | 9.7e-06 | 3.1e-04 | 900 | 189 | 14 | ADSL,DAP,GNPAT,IFI16,IMPACT,MTOR,NPRL2,NPRL3,OXCT1,PCK2,PDK4,SEH1L,SLC39A4,STK24 |
| GO_SENSORY_ORGAN_DEVELOPMENT | 9.9e-06 | 3.1e-04 | 900 | 549 | 26 | ALDH1A3,B9D1,BNC2,CC2D2A,COL8A1,CRYBA2,CYP1B1,EGFR,GRHL2,GSDME,IMPDH2,LHX1,LPCAT1,NECTIN3,NINJ1,PDGFRA,PRRX1,ROR1,SDHAF4,SLC4A7,TBX2,TFAP2B,TGIF2,TMEM231,TPRN,TTLL5 |
| GO_ATP_SYNTHESIS_COUPLED_ELECTRON_TRANSPORT | 1.0e-05 | 3.2e-04 | 900 | 97 | 10 | COX8A,ISCU,NDUFA7,NDUFB6,NDUFS1,NDUFV1,NDUFV3,PARK7,UQCC3,UQCRFS1 |
| GO_LIPID_CATABOLIC_PROCESS | 1.0e-05 | 3.1e-04 | 900 | 328 | 19 | ACOXL,ASAH2B,CES1,CYP19A1,CYP1B1,CYP4A11,GCDH,LONP2,MGLL,MMUT,MTOR,NAPEPLD,NCEH1,PCK2,PIK3CG,PNPLA4,SMPD2,SNX17,TYSND1 |
| GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 1.0e-05 | 3.2e-04 | 900 | 216 | 15 | CAV1,CBY1,EGR1,FERMT1,IGFBP4,KLHL12,MAD2L2,NLK,PSMB10,PSMB8,PSMB9,PSMD10,SFRP2,TMEM131L,UBAC2 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL | 1.0e-05 | 3.1e-04 | 900 | 299 | 18 | BABAM2,BIRC3,COPS6,COPS7A,DDB2,INO80C,MCRS1,PARK7,PSMB10,PSMB8,PSMB9,PSMD10,RUVBL1,SMAD1,USP19,USP20,USP4,USP45 |
| GO_PROTEIN_PROCESSING | 1.0e-05 | 3.2e-04 | 900 | 216 | 15 | BIRC3,CARD16,CASP1,CES1,F12,IFI16,LONP2,MIPEP,PLAU,PLGRKT,RHBDD1,RNF139,SCG5,SRGN,TYSND1 |
| GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 1.1e-05 | 3.3e-04 | 900 | 217 | 15 | BABAM2,EGFR,ERCC1,FBXO4,FMN2,MAD2L2,MUC1,NSMCE1,NSMCE4A,PSMD10,SFRP2,TAF9,TRIAP1,WDR70,WRNIP1 |
| GO_HEART_DEVELOPMENT | 1.2e-05 | 3.7e-04 | 900 | 589 | 27 | BORCS8,CBY1,CC2D2A,COX17,DLC1,DNAH5,EGFR,FOXF1,GRHL2,HAS2,IFT57,IFT74,MIB1,MICAL2,MKKS,MTOR,NEDD4,NPRL3,OXCT1,PDGFRA,SFRP2,SNX17,SPRY1,SRI,TBX2,TEK,VCAM1 |
| GO_ORGANELLE_LOCALIZATION | 1.2e-05 | 3.6e-04 | 900 | 622 | 28 | ADGRE2,ANKRD28,B9D1,BORCS5,CC2D2A,CEP63,EXOC6,FMN2,FOXF1,GRIA1,KLHL12,LAT2,MILR1,MKKS,MUL1,PIK3CG,PLXNA2,RAB11A,RAC2,SEH1L,SERPINA1,SNAP29,SPHK2,SPRY1,TMEM106B,TRAPPC4,TTL,ZNF593 |
| GO_COPPER_ION_TRANSPORT | 1.3e-05 | 3.9e-04 | 900 | 18 | 5 | COX17,MMGT1,SCO1,STEAP2,STEAP4 |
| GO_MEMBRANE_ORGANIZATION | 1.3e-05 | 3.9e-04 | 900 | 875 | 35 | AGK,ANKRD28,ARV1,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CAV1,CHCHD6,COLQ,CPLANE2,EGFR,GNPAT,GRIA1,KLHL12,MARCO,MICOS13,MTSS1,MUL1,NAIF1,NEK6,RAC2,RELN,RFT1,SERPINA1,SNAP29,STPG1,SYNGR2,TAP1,TRAPPC4,TRIAP1,UQCC3,VAMP2,VAMP4 |
| GO_RESPONSE_TO_NUTRIENT | 1.3e-05 | 3.9e-04 | 900 | 220 | 15 | ACSL4,ADSL,AHCY,AIFM1,CCND1,EGFR,ERCC1,GNPAT,MTOR,OXCT1,P2RX5,PEMT,SFRP2,TSPO,VCAM1 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 1.3e-05 | 3.9e-04 | 900 | 1698 | 56 | ADCY7,AGAP3,AIFM1,C1QTNF12,CA2,CAMKK2,CARD16,CASP1,CAV1,CCND1,CLDN1,CLK2,CRLS1,CYP1B1,DNAAF2,EDEM2,EGFR,EGR1,EIF2B5,EPS8,ERCC1,ESD,ESRRA,FIS1,GCH1,GCNT1,GGT5,GHRL,GNPAT,GSS,HBA2,HNRNPA0,IMPACT,JUNB,LRP8,MMP19,MTOR,OXCT1,P2RX5,PARK7,PCK2,PDCD1LG2,PDGFRA,PDK4,PEMT,PIK3CG,QDPR,SBNO2,SIGMAR1,SPHK2,SRI,STK24,TEK,TSPO,VAMP2,VCAM1 |
| GO_RETINOL_METABOLIC_PROCESS | 1.3e-05 | 3.9e-04 | 900 | 44 | 7 | ALDH1A1,ALDH1A3,AWAT2,CYP1B1,CYP2D6,PNPLA4,RDH5 |
| GO_CATION_TRANSPORT | 1.4e-05 | 4.0e-04 | 900 | 1180 | 43 | ARMC1,ATP5F1A,ATP5MC1,ATP5MC2,ATP5ME,ATP5PO,CALM2,CAV1,CLCN5,COX17,COX8A,F2RL3,GRIA1,ISCU,KCNG2,MMGT1,NCS1,NEDD4,NKAIN2,ORAI1,P2RX5,PARK7,PARL,PIK3CG,PKD1L1,RANGRF,RELN,SCO1,SLC24A1,SLC25A15,SLC39A4,SLC4A7,SLC9A3,SLC9A5,SPHK2,SRI,STEAP2,STEAP4,STK39,THADA,TRIM27,TSPO,VAMP2 |
| GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 1.5e-05 | 4.4e-04 | 900 | 463 | 23 | APCS,BIRC3,CARD16,CSTA,IFI16,LRCH1,MKKS,PARK7,PCID2,RNF34,SERPINA1,SERPINB3,SERPINB4,SFRP2,SPHK2,SPINK6,SPOCD1,SPRY1,TFAP2B,TMEM132D,TRIAP1,WFDC12,ZCCHC9 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 1.5e-05 | 4.4e-04 | 900 | 1107 | 41 | ARF6,ATP5F1A,BORCS5,CAV1,CCN4,CFAP298,CLDN1,CYP19A1,CYP1B1,DLC1,EGFR,ELP3,FOXF1,HAS2,IFITM1,LRCH1,MIIP,MKKS,MTOR,PDGFRA,PKN1,PKN2,PLAU,PLXNA2,PPM1F,PTPRG,PTPRJ,RAB11A,RAC2,RANGRF,RELN,RNF41,ROBO4,RYK,SERPINB3,SFRP2,SLAMF8,SRI,STK24,STK39,TEK |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 1.6e-05 | 4.6e-04 | 900 | 810 | 33 | B9D1,CAV1,COL8A1,CYP1B1,EGR1,FOXF1,GHRL,HAS2,JUNB,LEMD3,LIF,LRG1,MIB1,MMP19,NEDD4,NPRL3,NRARP,PDGFRA,PIK3CG,PRRX1,RASA1,RASIP1,ROBO4,SFRP2,SMAD1,SNX17,SPHK2,TBX2,TEK,TFAP2B,TLR3,TMEM231,XDH |
| GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 1.6e-05 | 4.6e-04 | 900 | 147 | 12 | ARNTL,CAV1,CSNK1G2,EGFR,NRARP,PLEKHA4,PSMB10,PSMB8,PSMB9,PSMD10,RUVBL1,SFRP2 |
| GO_RNA_SPLICING | 1.6e-05 | 4.7e-04 | 900 | 433 | 22 | CDK13,CLK2,CSTF1,GEMIN7,HNRNPA0,HNRNPF,HNRNPLL,LSM2,NCBP2,PCBP1,POLR2G,POLR2I,RBMXL1,SF3B3,SF3B5,THOC7,TRPT1,TSEN15,TSEN2,UBL5,USP4,ZCRB1 |
| GO_SENSORY_SYSTEM_DEVELOPMENT | 1.6e-05 | 4.5e-04 | 900 | 369 | 20 | ALDH1A3,B9D1,CC2D2A,COL8A1,CRYBA2,CYP1B1,EGFR,GRHL2,IMPDH2,LHX1,LPCAT1,NECTIN3,NINJ1,PDGFRA,SDHAF4,TBX2,TFAP2B,TGIF2,TMEM231,TTLL5 |
| GO_NEURON_DEVELOPMENT | 1.7e-05 | 4.9e-04 | 900 | 1114 | 41 | ACSL4,ARF6,BAG5,BDNF,BTBD3,EGFR,ETV1,FRY,GHRL,IMPACT,LHX1,LIF,LRP8,MTOR,MUL1,NCAM2,NCS1,NEDD4,NEGR1,PLXNA2,PRDM12,PRRX1,PTPRG,RAB11A,RAC2,RELN,RERE,ROBO4,ROR1,RYK,S100A6,SECISBP2,SFRP2,SLC4A7,SS18L2,STK24,TMEM106B,TPRN,TRAPPC4,TSPO,TTL |
Num: 10 (Pathways: 247 DK: 7)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (7) | BRSK2, CDK18, CDKL2, LTK, MAP3K14, STK31, STK33 |
| Light Kinase (15) | ACVR1B, AKT3, DAPK3, EPHA4, FES, FYN, GRK5, LCK, MAP3K9, MAP4K5, MERTK, NPR2, PRKG1, TNK1, TNNI3K |
| Non-kinase Count | 714 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 736 | 1425 | 79 | ABAT,ACTB,ADAM19,ADAM9,ADGRV1,APLP1,ARVCF,ATP4B,BMP7,BSG,CCN6,CD24,CD96,CDH20,CDHR4,CITED2,CLDN18,CLDN6,CLSTN2,CNTN5,COL5A1,DAPK3,DGCR6,EPHA4,F11R,FAM107A,FAT3,FBN1,FES,FLNA,FYN,GSN,HAPLN3,HMCN1,IGF2,IL2RA,ITGA8,ITGB6,KITLG,LAG3,LAMC3,LCK,LGALS9,LYPD3,MELTF,MERTK,MMP24,MYOT,NECTIN4,NID2,PCDHA1,PCDHA2,PCDHA9,PCDHB12,PCDHB18P,PCDHB3,PCDHB6,PCDHB7,PCDHGA12,PCDHGA4,PCDHGB1,PCDHGB3,PCDHGB5,PDE5A,PERP,PLG,PREX1,PRKG1,PTN,RHOB,S100A8,SIGLEC10,SLC9A1,SOX9,SSPN,STRC,TECTA,TLN2,WNT7B |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 1935 | 93 | ABAT,ABCG8,ACKR2,ACP5,ACTB,ACVR1B,ADGRV1,ADRA1B,AQP1,AQP3,ATG5,ATP1A1,ATP2A1,ATP4B,BRSK2,C1QTNF3,C5AR1,CD24,CIB2,CLDN18,CLTRN,CRY2,CTSK,DMD,EPHX2,FABP4,FHL1,FOXO3,FOXO6,FYN,G6PD,GIPR,GJB6,GRIK2,GRIN2A,H4C15,HEPH,HPX,ID2,IFI6,IL2RA,IL31RA,KCNB1,KCNK3,KITLG,LCK,LGALS9,LIPA,LOX,MAP1A,MCOLN2,MEF2C,MELTF,MERTK,MLXIPL,MYO5A,NAPSA,NME9,NXNL2,P2RY2,P2RY4,PDE6B,PICALM,PKIB,PLCL1,PLG,PPARGC1A,PPP2R3C,PROM1,PTGIR,PTH2R,RBP4,RYR2,S100A14,S100A8,SCARA5,SLC12A7,SLC17A7,SLC27A1,SLC30A1,SLC7A8,SLC9A1,SOX9,SREBF2,TBXA2R,TFF2,TFR2,TRPC3,TRPC6,TXNDC2,WFS1,WHRN,WNT7B |
| GO_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 1692 | 85 | ABAT,ABCG8,ACSL3,AGXT,AQP1,ATG5,ATP10B,ATP1A1,ATP2A1,ATP4B,ATP8A1,BEST3,CALHM5,COX8C,CRY2,DMD,EHD3,FABP4,FHL1,FLNA,FLVCR2,FYN,G6PD,GABRR2,GIPC1,GJC2,GPM6A,GRIA2,GRIK2,GRIN2A,HEPH,HPX,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MEF2C,MELTF,MT-CO1,MT-CO3,MT-CYB,MT-ND4,MYO5A,NDUFA4,OPRM1,P2RY4,PIEZO2,PLCL1,PLEKHA8,PPARGC1A,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC23A2,SLC25A41,SLC26A9,SLC27A1,SLC28A3,SLC30A1,SLC39A11,SLC47A1,SLC6A20,SLC7A8,SLC9A1,SNTA1,STARD5,STOM,SYT11,TFR2,TMC3,TMEM163,TREM2,TRPC3,TRPC6,UNC79,VPS9D1,WFS1,YWHAQ |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 736 | 1665 | 82 | ABAT,ADGRA2,ADRA1B,AMPH,BRSK2,BSN,C1QTNF3,CCL16,CCN6,CD24,CGB7,CLSTN2,CLTRN,DAAM1,DAGLB,DAPK3,EFNA4,EPHA4,FAM107A,FGF11,FLNA,FYN,FZD2,GABBR2,GABRR2,GIPC1,GIPR,GJC2,GNG2,GRIA2,GRIK2,GRIN2A,GRK5,ITPKA,KCNB1,KCNK3,KCNS3,KREMEN1,LGI1,LGR6,LIMD1,LIN7B,LRP4,MAP1A,MAPT,MEF2C,MERTK,MYO5A,MYRIP,NFATC1,NPTXR,OPRM1,P2RY4,PCDHB3,PCDHB6,PDE6B,PLCL1,PLG,PPP1R9A,PTGIR,PTN,RASD2,RASL10B,RBP4,RYR2,S100A8,SLC12A7,SLC17A7,SLC30A1,SNPH,SOX9,STX1B,SYN1,SYNGR1,SYT11,TFR2,TMEM170B,TNRC6B,TUBB2B,WNT10A,WNT7B,WNT9A |
| GO_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 1180 | 65 | ABAT,AQP1,ATG5,ATP1A1,ATP2A1,ATP4B,ATP8A1,COX8C,DMD,EHD3,FHL1,FLNA,FLVCR2,FYN,G6PD,GJC2,GPM6A,GRIA2,GRIN2A,HEPH,HPX,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MEF2C,MELTF,MT-CO1,MT-CO3,MT-CYB,MT-ND4,MYO5A,NDUFA4,OPRM1,PIEZO2,PLCL1,PPARGC1A,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC23A2,SLC28A3,SLC30A1,SLC39A11,SLC47A1,SLC6A20,SLC7A8,SLC9A1,SNTA1,STOM,SYT11,TFR2,TMEM163,TREM2,TRPC3,TRPC6,VPS9D1,WFS1 |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 1160 | 63 | AQP1,ATG5,ATP1A1,ATP2A1,ATP4B,ATP8A1,BEST3,COX8C,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GABRR2,GJC2,GPM6A,GRIA2,GRIK2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MEF2C,MT-CO1,MT-CO3,MT-CYB,MT-ND4,MYO5A,NDUFA4,OPRM1,PIEZO2,PLCL1,PPARGC1A,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC23A2,SLC26A9,SLC28A3,SLC30A1,SLC39A11,SLC6A20,SLC7A8,SLC9A1,SNTA1,STOM,TMC3,TMEM163,TREM2,TRPC3,TRPC6,UNC79,VPS9D1,YWHAQ |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 879 | 54 | AQP1,ATG5,ATP1A1,ATP2A1,ATP4B,ATP8A1,COX8C,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GJC2,GPM6A,GRIA2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MEF2C,MT-CO1,MT-CO3,MT-CYB,MT-ND4,MYO5A,NDUFA4,OPRM1,PIEZO2,PLCL1,PPARGC1A,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC28A3,SLC30A1,SLC39A11,SLC6A20,SLC9A1,SNTA1,STOM,TMEM163,TREM2,TRPC3,TRPC6,VPS9D1 |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 736 | 1141 | 62 | ACTB,ANKRD1,ARHGEF18,ARTN,BMP7,BRSK2,BSG,DAPK3,EFNA4,EPHA4,F11R,FES,FLNA,FYN,GAB1,GPM6A,ID2,ITGA8,ITPKA,KRT8,LAMC3,LGI1,LGR6,LHX9,LIMD1,LIPA,LMOD3,LRP4,MAEL,MAP1A,MAPT,MATN2,MATN4,MEF2A,MEF2C,MELTF,MERTK,MYO9A,MYOM2,MYOT,PALM,PARD6B,PICALM,POU3F2,PPP1R9A,PREX1,PROX1,PTN,RAP2A,RHOB,RHOU,RILPL2,SPTBN5,STRC,TRAK1,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WHRN,WNT7B |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 1604 | 75 | ABCG8,ACTB,AQP1,AQP3,ATG5,ATP1A1,ATP2A1,ATP4B,ATP8A1,BEST3,C2orf83,CLIP3,COX8C,DMD,EHD3,FHL1,FLNA,FLVCR2,FYN,G6PD,GABRR2,GJB6,GJC2,GPM6A,GRIA2,GRIK2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MEF2A,MEF2C,MT-CO1,MT-CO3,MT-CYB,MT-ND4,MYO5A,NDUFA4,OPRM1,PEX16,PIEZO2,PLCL1,PPARGC1A,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC23A2,SLC25A41,SLC26A9,SLC28A3,SLC2A13,SLC30A1,SLC39A11,SLC47A1,SLC6A20,SLC7A8,SLC9A1,SNTA1,STOM,TMC3,TMEM163,TREM2,TRPC3,TRPC6,UNC79,VPS9D1,YWHAQ |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 1894 | 82 | ABAT,ABCG8,ACAA2,ACSL3,ACTB,ADAM9,ANKRD1,AQP1,ATG5,ATP1A1,ATP2A1,ATP8A1,BEST3,BRSK2,BSN,C1QTNF3,C4BPB,CLIP3,CLTRN,CRY2,CRYAB,DMD,EHD3,FES,FHL1,FLNA,FYN,G6PD,GIPC1,GIPR,GJC2,GRASP,GRIA2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNS3,LGALS9,MEF2A,MEF2C,MERTK,MX2,MYO5A,MYRIP,NDRG4,OPRM1,P2RY2,P2RY4,P3H1,PAM,PICALM,PPARGC1A,PPP1R9A,PROM2,RALB,RASL10B,RBP4,RHOU,RYR2,S100A8,SCN2A,SEC16B,SLC17A7,SLC30A1,SLC9A1,SNTA1,SREBF2,STOM,STON2,STX1B,SYN1,SYT11,TFF2,TFR2,TREM2,TRPC3,TRPC6,WFS1,YWHAQ |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 736 | 1545 | 72 | ACTB,ADGRV1,AIF1L,ANKRD1,ARTN,ATG5,BBS9,BMP7,BRSK2,BSG,CCDC103,CCDC114,CCDC65,DNAJB13,EFNA4,EHD3,EPHA4,FES,FLNA,FNBP1L,FOXO6,FYN,GAB1,GMNC,GPM6A,GSN,ITGA8,ITPKA,KREMEN1,LCA5L,LGI1,LGR6,LHX9,LRP4,LTK,MAP1A,MAPT,MATN2,MEF2A,MEF2C,MYO9A,MYOT,NDRG4,NME5,P3H1,PALM,PARD6B,PICALM,PIH1D3,POU3F2,PPP1R9A,PREX1,PRKG1,PROM2,PTN,RAP2A,RHOU,RSPH1,SPTBN5,STRC,STX1B,TRAK1,TREM2,TRPC6,TUBA1A,TUBB2B,UNC5C,USP9X,VLDLR,WDR63,WHRN,WNT7B |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 766 | 49 | ACTB,AIF1L,AMOT,ANKRD1,AQP1,ARHGEF18,ATP1A1,ATP2A1,BRSK2,CGNL1,CNN1,DAAM1,DAPK3,DES,DMD,EHBP1,ELMO1,F11R,FAM107A,FES,FLNA,FNBP1L,GAB1,GSN,ITPKA,KCND3,KCNE2,KRT8,LMOD3,MEF2A,MEF2C,MYO5A,MYOM2,PAM,PFN4,PPP1R9A,PREX1,PRKG1,PROX1,RAP2A,RHOB,RHOU,RYR2,SH3PXD2B,SLC9A1,SNTA1,SPTBN5,SYNPO2,WIPF3 |
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 736 | 1625 | 74 | ACTB,ADGRV1,ANKRD1,ARTN,BMP7,BRSK2,BSG,BTG4,C5AR1,DAGLB,DAPK3,EFNA4,EPHA4,FES,FLNA,FOXO6,FYN,FZD2,GAB1,GJC2,GPM6A,GRIN2A,GSN,HDAC11,ID2,ITPKA,KREMEN1,LAMC3,LGI1,LGR6,LHX9,LRP4,LTK,MAP1A,MAPT,MATN2,MEF2A,MEF2C,MMP24,MYO9A,MYOT,NAP1L2,NDRG4,OPRM1,P3H1,PARD6B,PICALM,POU3F2,PPP1R9A,PREX1,PRKG1,PROM1,PROX1,PTN,RAP2A,S100A8,SNPH,SOX9,SPTBN5,STRC,STX1B,SYN1,THRB,TRAK1,TREM2,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WHRN,WNT10A,WNT7B,WNT9A |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 736 | 1335 | 66 | ACTB,AIF1L,AMOT,ANKRD1,AQP1,ARHGEF18,BRSK2,CCDC103,CCDC114,CCDC65,CCDC8,CGNL1,CLIP3,CNN1,CRYAB,DAAM1,DAPK3,DES,DMD,DNAJB13,EHBP1,ELMO1,EPPK1,F11R,FAM107A,FES,FLNA,GAB1,GOLGA8R,GSN,ITPKA,KRT8,LIMD1,LMOD3,MAP1A,MAP9,MAPT,MEF2A,MEF2C,MYOM2,PALM,PAM,PARD6B,PFN4,PIH1D3,PPP1R9A,PPP2R3C,PREX1,PRKG1,PROX1,RAP2A,RHOB,RHOU,RSPH1,S100A8,SH3PXD2B,SLC9A1,SOX9,SPTBN5,SUN3,SYNPO2,TLN2,TUBA1A,TUBB2B,WDR63,WIPF3 |
| GO_CHEMICAL_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 736 | 1207 | 62 | ABCG8,ACKR2,ADRA1B,AQP1,AQP3,ATG5,ATP1A1,ATP2A1,ATP4B,BRSK2,C1QTNF3,C5AR1,CD24,CIB2,CLTRN,CRY2,DMD,EPHX2,FABP4,FHL1,FOXO3,FOXO6,FYN,GIPR,GJB6,GRIK2,GRIN2A,HEPH,HPX,IFI6,KCNB1,KCNK3,LCK,MCOLN2,MELTF,MLXIPL,MYO5A,NAPSA,P2RY2,P2RY4,PDE6B,PICALM,PLCL1,PPARGC1A,PPP2R3C,PTGIR,RBP4,RYR2,S100A14,S100A8,SCARA5,SLC12A7,SLC30A1,SLC7A8,SLC9A1,SREBF2,TBXA2R,TFR2,TRPC3,TRPC6,WFS1,WNT7B |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 736 | 1698 | 75 | ABAT,ACP5,ACTB,ADAM9,AGXT,ANKRD1,APLP1,AQP1,AQP3,ATP1A1,ATP4B,BMP7,BRSK2,BSG,C5AR1,CBX8,CD96,CIB2,CLDN18,CLTRN,CRYAB,EPHA4,FBN1,FES,FLNA,FOXO3,FOXO6,FYN,G6PD,GAB1,GIPR,GJB6,GNG2,GRIN2A,GSN,IGF2,INSIG2,KCNB1,KRT8,LGALS9,LTK,MAPT,MEF2C,MLXIPL,MMP15,MT-CYB,MT-ND1,MT-ND4,MYO5A,NSG2,OPRM1,P2RY2,P2RY4,PALM,PAM,PPARGC1A,PTGIR,PTN,RBP4,RHOB,RYR2,S100A14,S100A8,SLC27A1,SLC9A1,SLPI,SOX9,TBXA2R,TICAM2,TREM2,TRPC3,TRPC6,UNC79,WNT7B,WNT9A |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 736 | 1984 | 82 | ACKR2,ACTB,ACVR1B,ADAM9,ADGRA2,AKT3,AMOT,ARTN,ATP8A1,BMP7,BSG,BTC,C5AR1,CCDC65,CCL16,CD24,CITED2,COL5A1,DAPK3,EFNA4,ELMO1,EPHA4,EPPK1,F11R,FAM107A,FES,FLNA,FOXO3,FYN,GAB1,GIPC1,GPM6A,GRIN2A,ID2,IGLV1-51,ITGB6,KITLG,LAMC3,LCK,LGALS9,LGI1,LGR6,LHX9,LIMD1,LOX,MATN2,MCOLN2,MEF2C,MERTK,MYO5A,MYOT,NDRG4,NRG4,PARD6B,PIH1D3,PLG,PLVAP,POU3F2,PPARGC1A,PREX1,PRKG1,PROX1,PTN,RAP2A,RHOB,S100A14,S100A8,SLC7A8,SLC9A1,SOX9,SPTBN5,TBXA2R,TNS1,TREM2,TRIM62,TUBB2B,UNC5C,USP9X,VASH1,VLDLR,VPREB3,WDR63 |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 860 | 51 | AQP1,ATG5,ATP1A1,ATP2A1,ATP4B,BEST3,COX8C,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GABRR2,GJC2,GPM6A,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MT-CO1,MT-CO3,MT-CYB,MT-ND4,MYO5A,NDUFA4,OPRM1,PLCL1,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC26A9,SLC28A3,SLC30A1,SLC39A11,SLC9A1,SNTA1,STOM,TMEM163,TREM2,TRPC3,TRPC6,VPS9D1 |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 736 | 847 | 49 | ABAT,ACTB,ADAM19,ADAM9,ADGRV1,ARVCF,BMP7,BSG,CD24,CDH20,CDHR4,CITED2,CLDN18,CLDN6,CLSTN2,F11R,FAT3,FLNA,FYN,HMCN1,IGF2,IL2RA,ITGA8,LAG3,LCK,LGALS9,MMP24,MYOT,NECTIN4,PCDHA1,PCDHA2,PCDHA9,PCDHB12,PCDHB18P,PCDHB3,PCDHB6,PCDHB7,PCDHGA12,PCDHGA4,PCDHGB1,PCDHGB3,PCDHGB5,PDE5A,PERP,PLG,PRKG1,S100A8,SOX9,WNT7B |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 1825 | 75 | ABAT,ACVR1B,ADAM9,ADGRA2,ADGRV1,ADRA1B,AKT3,AMOT,ANKRD1,AQP1,ATG5,ATP1A1,ATP2A1,BMP7,C1QTNF3,C5AR1,CD101,CD24,CITED2,CLSTN2,ENPP4,EPHA4,F11R,FABP4,FES,FLNA,FOXO3,FOXO6,FYN,GAB1,GJC2,ID2,IGF2,IL2RA,ITPKA,KITLG,LGALS9,LMOD3,LTK,LUM,MAPT,MCOLN2,MEF2A,MEF2C,NAP1L2,NDRG4,OPRM1,OSR2,P2RY2,P3H1,PDE5A,PLG,POU3F2,PPARGC1A,PPP1R9A,PPP2R3C,PROM1,PROX1,PTH2R,PTN,RHOB,RYR2,SH3PXD2B,SLC27A1,SLC9A1,SOX9,STX1B,TBXA2R,TRAK1,TREM2,TRPC3,TRPC6,TUBB2B,VLDLR,WNT7B |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 736 | 748 | 45 | ACTB,ARTN,BMP7,BRSK2,BSG,EFNA4,EPHA4,FLNA,FYN,GAB1,ID2,ITGA8,ITPKA,LAMC3,LGI1,LGR6,LHX9,LRP4,MAP1A,MAPT,MATN2,MATN4,MEF2A,MEF2C,MELTF,MERTK,MYOT,PARD6B,PICALM,POU3F2,PPP1R9A,PREX1,PROX1,PTN,RAP2A,RILPL2,SPTBN5,STRC,TRAK1,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WHRN |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 736 | 1881 | 76 | ACVR1B,ADGRA2,ADGRV1,ANKRD1,AQP3,BMP7,BRSK2,BTC,CD101,CD24,CLDN18,COL5A1,CTSK,EPHA4,F11R,FBN1,FES,FLNA,FOXO3,FOXO6,FYN,G6PD,GJC2,H4C15,HSF4,ID2,IGF2,IKZF3,IL2RA,ITPKA,KITLG,KREMEN1,L3MBTL1,LAG3,LGALS9,LIMD1,LMOD3,LOX,LRP4,LTK,MAPT,MEF2A,MEF2C,MELTF,MMP11,MYO9A,NAP1L2,NDRG4,NFATC1,NKX3-2,NPR2,OPRM1,P3H1,PDE5A,POU3F2,PPP1R9A,PPP2R3C,PREX1,PROM1,PROX1,PTN,RAP2A,SH3PXD2B,SOX9,STX1B,THRB,TNRC6B,TOB1,TRAK1,TREM2,TRIM62,TRPC6,TUBB2B,VLDLR,WNT7B,WNT9A |
| GO_CELLULAR_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 736 | 963 | 51 | ACKR2,ADRA1B,AQP1,ATG5,ATP1A1,ATP2A1,ATP4B,BRSK2,C1QTNF3,C5AR1,CD24,CIB2,CLTRN,DMD,EPHX2,FYN,GIPR,GJB6,GRIK2,GRIN2A,HEPH,HPX,KCNB1,KCNK3,LCK,LOX,MAP1A,MCOLN2,MLXIPL,MYO5A,NME9,P2RY2,P2RY4,PDE6B,PLCL1,PLG,PPARGC1A,PTGIR,RYR2,S100A8,SCARA5,SLC12A7,SLC17A7,SLC30A1,SLC9A1,TBXA2R,TFR2,TRPC3,TRPC6,TXNDC2,WFS1 |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 736 | 1365 | 62 | ACTB,ADGRV1,ANKRD1,ARTN,BMP7,BRSK2,BSG,BTG4,DAPK3,EFNA4,EPHA4,FES,FOXO6,FYN,FZD2,GAB1,GPM6A,ID2,ITPKA,KREMEN1,LGI1,LGR6,LHX9,LRP4,LTK,MAP1A,MAPT,MATN2,MEF2A,MEF2C,MYO9A,MYOT,NAP1L2,NDRG4,P3H1,PARD6B,PICALM,POU3F2,PPP1R9A,PREX1,PRKG1,PROM1,PROX1,PTN,RAP2A,SNPH,SOX9,SPTBN5,STRC,STX1B,SYN1,THRB,TRAK1,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WHRN,WNT10A,WNT7B,WNT9A |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 736 | 1758 | 72 | ACKR2,ACTB,ACVR1B,ADAM9,ADGRA2,AKT3,AMOT,ARTN,ATP8A1,BMP7,BSG,BTC,C5AR1,CCDC65,CCL16,CD24,CITED2,COL5A1,DAPK3,ELMO1,EPHA4,EPPK1,F11R,FAM107A,FES,FLNA,FOXO3,FYN,GAB1,GIPC1,GPM6A,IGLV1-51,ITGB6,KITLG,LAMC3,LCK,LGALS9,LGR6,LIMD1,LOX,MATN2,MCOLN2,MEF2C,MERTK,NDRG4,NRG4,PARD6B,PIH1D3,PLG,PLVAP,POU3F2,PPARGC1A,PREX1,PRKG1,PROX1,PTN,RAP2A,RHOB,S100A14,S100A8,SLC7A8,SLC9A1,SOX9,TBXA2R,TNS1,TREM2,TUBB2B,UNC5C,USP9X,VASH1,VPREB3,WDR63 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 736 | 1930 | 75 | ACOT4,ACSL3,ACTB,AGXT,AMOT,ARL4C,ARL5B,ASTN2,BBS9,BMF,BMP7,BRSK2,BSG,CD24,CLDN18,CLIP3,DMD,ECH1,EHD3,EPHX2,F11R,FAF2,FLNA,FYN,GIPC1,GRASP,GRIK2,GRIN2A,GSN,KCNB1,LCA5L,LGI1,LIN7B,LRP4,MAP1A,MAPT,MX2,MYO5A,MYRIP,PALM,PEX16,PFN4,PICALM,PIPOX,PTN,RAB30,RAB36,RAB40A,RAB6B,RALB,RAP2A,RHOB,RHOU,RILPL2,RYR2,SEC16B,SEC31B,SH3PXD2B,SOX9,SREBF2,STOM,STX1B,SUN3,SYNGR1,SYT11,SYTL3,TBC1D8B,TICAM2,TLN2,TM9SF2,TRAK1,TREM2,USP9X,XPA,YWHAQ |
| GO_METAL_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 906 | 48 | AQP1,ATG5,ATP1A1,ATP2A1,ATP4B,DMD,EHD3,FHL1,FLNA,FLVCR2,FYN,G6PD,GJC2,GPM6A,GRIN2A,HEPH,HPX,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,LCK,MCOLN2,MELTF,MYO5A,OPRM1,PLCL1,RYR2,SCARA5,SCN2A,SLC12A7,SLC17A7,SLC23A2,SLC28A3,SLC30A1,SLC39A11,SLC9A1,SNTA1,STOM,TFR2,TMEM163,TREM2,TRPC3,TRPC6,WFS1 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 736 | 1994 | 76 | ACTB,ACVR1B,ADAM9,ADRA1B,AKT3,ARHGAP8,ARTN,BMP7,BMP8B,BRSK2,BTC,C5AR1,CCL16,CCNI2,CD24,CDK18,CDKL2,CLIP3,CRYAB,DAPK3,DMD,EPHA4,FABP4,FES,FYN,GJC2,GRIK2,GRK5,HPX,IGF2,IL2RA,IL31RA,ITPKA,KITLG,LCK,LGALS9,LOX,LRP4,LTK,MAP3K14,MAP3K9,MAP4K5,MEF2A,MEF2C,MERTK,MEX3B,MLXIPL,NDRG4,NPR2,NRG4,OPRM1,OR2AT4,PDE5A,PKIB,PLCL1,PLVAP,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,RALB,RAP2A,RASGRP4,RNF149,SLC27A1,SOX9,SPTBN5,STK31,STK33,TNK1,TNNI3K,TREM2,TRPC6,VLDLR,WNT7B |
| GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 0.0e+00 | 736 | 167 | 21 | BSG,CDH20,CDHR4,CLSTN2,FAT3,HMCN1,MYOT,NECTIN4,PCDHA1,PCDHA2,PCDHA9,PCDHB12,PCDHB18P,PCDHB3,PCDHB6,PCDHB7,PCDHGA12,PCDHGA4,PCDHGB1,PCDHGB3,PCDHGB5 |
| GO_METAL_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 736 | 667 | 40 | ACKR2,ADRA1B,ATG5,ATP1A1,ATP2A1,ATP4B,C5AR1,CD24,CIB2,DMD,EPHX2,FYN,GIPR,GRIK2,GRIN2A,HEPH,HPX,KCNK3,LCK,MCOLN2,MELTF,MYO5A,P2RY4,PDE6B,PICALM,PLCL1,PTGIR,RYR2,S100A14,S100A8,SCARA5,SLC12A7,SLC30A1,SLC7A8,SLC9A1,TBXA2R,TFR2,TRPC3,TRPC6,WFS1 |
| GO_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 736 | 831 | 45 | ACKR2,ADRA1B,ATG5,ATP1A1,ATP2A1,ATP4B,C5AR1,CD24,CIB2,DMD,EPHX2,FHL1,FYN,GIPR,GRIK2,GRIN2A,HEPH,HPX,IFI6,KCNK3,LCK,MCOLN2,MELTF,MLXIPL,MYO5A,P2RY2,P2RY4,PDE6B,PICALM,PLCL1,PPP2R3C,PTGIR,RYR2,S100A14,S100A8,SCARA5,SLC12A7,SLC30A1,SLC7A8,SLC9A1,TBXA2R,TFR2,TRPC3,TRPC6,WFS1 |
| GO_SYNAPTIC_SIGNALING | 0.0e+00 | 0.0e+00 | 736 | 733 | 42 | ABAT,AMPH,BSN,CLSTN2,DAGLB,EPHA4,FAM107A,FYN,GABBR2,GABRR2,GIPC1,GRIA2,GRIK2,GRIN2A,ITPKA,KCNB1,KCNK3,LGI1,LIN7B,MAP1A,MAPT,MEF2C,MYO5A,NPTXR,OPRM1,P2RY4,PCDHB3,PCDHB6,PLCL1,PLG,PPP1R9A,PTN,RASD2,SLC12A7,SLC17A7,SLC30A1,SNPH,STX1B,SYN1,SYNGR1,SYT11,TUBB2B |
| GO_NEURON_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 736 | 1114 | 53 | ACTB,ADGRV1,ANKRD1,ARTN,BMP7,BRSK2,BSG,EFNA4,EPHA4,FES,FOXO6,FYN,FZD2,GAB1,GPM6A,ID2,ITPKA,KREMEN1,LGI1,LGR6,LHX9,LRP4,LTK,MAP1A,MAPT,MATN2,MEF2A,MEF2C,MYO9A,MYOT,NDRG4,P3H1,PARD6B,PICALM,POU3F2,PPP1R9A,PREX1,PRKG1,PTN,RAP2A,SPTBN5,STRC,STX1B,SYN1,THRB,TRAK1,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WHRN,WNT7B |
| GO_SENSORY_ORGAN_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 736 | 549 | 36 | ADGRV1,ATG5,BMP7,COL5A1,CRYAB,CRYGS,EPHA4,FBN1,FZD2,GJB6,GPM6A,HSF4,INSIG2,ITGA8,KCNE2,KCNK3,LAMC3,LRIG1,MERTK,MYOM2,NKX3-2,OSR2,PDE6B,PROM1,PROX1,PTN,RBP4,SH3PXD2B,SLC17A7,SOX9,STRC,THRB,WHRN,WNT10A,WNT7B,WNT9A |
| GO_REGULATION_OF_MEMBRANE_POTENTIAL | 0.0e+00 | 0.0e+00 | 736 | 435 | 32 | ABAT,ATP1A1,CCN6,DMD,EHD3,FHL1,FLNA,GABRR2,GRIA2,GRIK2,GRIN2A,IFI6,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,MAPT,MEF2C,OPRM1,PIEZO2,PPP1R9A,PPP2R3C,PTN,RYR2,SCN2A,SLC17A7,SLC9A1,SNTA1,STX1B,TREM2 |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 736 | 1061 | 51 | ABAT,ABCG8,ACTB,ADAM9,ADSS1,ANKRD1,AQP1,ATG5,ATP1A1,CBX8,CIB2,CLDN18,CRYAB,FLNA,FYN,G6PD,GNG2,GRIN2A,GSN,KCNE2,KCNK3,LCK,LOX,MEF2C,MT-CYB,MT-ND1,MT-ND4,NSG2,OPRM1,P2RY2,P2RY4,PALM,PAM,PPARGC1A,PTN,RAP2A,RBP4,RHOB,RNF149,RYR2,S100A8,SLC17A7,SLC25A41,SLC47A1,SLC6A20,SOX9,SYT11,TBXA2R,TRPC3,TRPC6,UNC79 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 736 | 1869 | 71 | ABAT,ACVR1B,ADAM9,ADGRA2,ADGRV1,ADRA1B,ANKRD1,ARHGAP8,BMF,BMP7,BMP8B,BTC,C1QTNF3,C5AR1,CCL16,CD24,CIDEB,CITED2,CLSTN2,CLTRN,DAPK3,EPHA4,F11R,FAM107A,FLNA,FYN,FZD2,GAB1,GIPC1,GIPR,GRIK2,GRIN2A,GSN,HPX,IGF2,IL10RB,IL31RA,ITGA8,KITLG,LCK,LGALS9,LGI1,LGR6,MAP3K14,MAP3K9,MAP4K5,MYRIP,NDRG4,NPR2,NRG4,OPRM1,OR2AT4,PDE5A,PPP1R9A,PTN,RASD2,RASGRP4,RASL10B,RBP4,S100A8,SLC9A1,SOX9,STX1B,TFR2,TICAM2,TOB1,TREM2,TRIM62,WNT7B,WNT9A,YWHAQ |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 1428 | 60 | ACVR1B,ADAM9,ADGRV1,AKT3,AMOT,ANKRD1,AQP1,BMP7,BTC,C5AR1,CD101,CD24,CITED2,CLSTN2,EPHA4,F11R,FES,FLNA,FOXO3,FOXO6,FYN,GAB1,GJC2,HSF4,ID2,IGF2,IL2RA,ITPKA,KITLG,LGALS9,LMOD3,LTK,MAPT,MEF2A,MEF2C,NAP1L2,NDRG4,OPRM1,OSR2,P3H1,PDE5A,POU3F2,PPARGC1A,PPP1R9A,PPP2R3C,PREX1,PROM1,PROX1,PTN,RHOB,SH3PXD2B,SOX9,TBXA2R,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR,WNT7B,WNT9A |
| GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 0.0e+00 | 0.0e+00 | 736 | 274 | 25 | ARVCF,BSG,CDH20,CDHR4,CLDN18,CLDN6,CLSTN2,FAT3,HMCN1,MMP24,MYOT,NECTIN4,PCDHA1,PCDHA2,PCDHA9,PCDHB12,PCDHB18P,PCDHB3,PCDHB6,PCDHB7,PCDHGA12,PCDHGA4,PCDHGB1,PCDHGB3,PCDHGB5 |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 736 | 1235 | 55 | ABAT,ACAA2,ADGRV1,ADSS1,ANKRD1,AQP1,AQP3,ATP1A1,BMF,BMP7,CD24,CITED2,CRY2,CRYAB,DMD,F11R,FYN,GJB6,GRIN2A,HSF4,HSFX1,ID2,KCNK3,KRT8,LIMD1,MAP3K14,MAPT,MMP24,MT-CO1,MT-CYB,MT-ND3,MT-ND4,NDRG4,OPRM1,PALM,PAM,PDE6B,PIEZO2,PPARGC1A,PTN,RGS9BP,RHOB,RYR2,SCARA5,SCN2A,SLC27A1,SLC9A1,SOX9,STRC,TAFA2,TMEM135,TRPC3,TRPC6,WHRN,XPA |
| GO_NERVOUS_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 1441 | 60 | ABAT,ADGRV1,ATP8A1,BBS9,C5AR1,CNTN5,CRYGS,FAM107A,FOXO6,FYN,FZD2,GABRR2,GJB6,GRIK2,GRIN2A,HMCN1,HSF4,ITGA8,LAMC3,LRIG1,LUM,MAP1A,MAPT,MEF2C,MMP24,MYO5A,MYO9A,NDRG4,NPTXR,NXNL2,OPRM1,OR10G4,OR10Z1,OR2AT4,OR2M3,OR2T33,OR4K17,OR52I1,OTOGL,PDE6B,PICALM,PIEZO2,PPP1R9A,PTN,RBP4,RETREG1,RGS9BP,SCN2A,SLC17A7,SLC9A1,STRC,STX1B,SYT11,TAFA2,TAS1R3,TECTA,THRB,VLDLR,WFS1,WHRN |
| GO_MUSCLE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 470 | 32 | ABAT,ADRA1B,ARHGAP42,ATP1A1,ATP2A1,CNN1,CRYAB,DAPK3,DES,DMD,EHD3,FLNA,FOXO3,G6PD,GSN,KCND3,KCNE2,LMOD3,MEF2A,MEF2C,MYOM2,MYOT,PDE5A,PPARGC1A,PRKG1,RYR2,SLC9A1,SNTA1,SSPN,TBXA2R,TNNI3K,TRPC3 |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 736 | 1071 | 50 | ACP5,ANKRD1,APLP1,AQP1,AQP3,BMP7,BSG,CCDC103,CITED2,COL5A1,DAAM1,DGCR6,FBN1,FHL1,FZD2,GJB6,ID2,IGF2,INSIG2,IRX4,ITGA8,LAMC3,LHX9,LRIG1,LRP4,MATN2,MATN4,MEF2C,MYO5A,MYOM2,NDRG4,NKX3-2,OSR2,PAM,PERP,PROM1,PROX1,PTN,RBP4,RYR2,SH3PXD2B,SOX9,SSUH2,STRC,SYCP2,THRB,WHRN,WNT10A,WNT7B,WNT9A |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 736 | 592 | 36 | ACTB,ARTN,BMP7,BRSK2,BSG,EFNA4,EPHA4,FYN,GAB1,ID2,ITPKA,LGI1,LGR6,LHX9,LRP4,MAP1A,MAPT,MATN2,MEF2A,MEF2C,MYOT,PARD6B,PICALM,POU3F2,PPP1R9A,PTN,RAP2A,SPTBN5,STRC,TRAK1,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WHRN |
| GO_REGULATION_OF_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 614 | 36 | ABAT,ABCG8,ADRA1B,AQP1,ARHGAP42,ATP1A1,ATP2A1,C1QTNF3,CNN1,DAPK3,DES,DMD,EHD3,FLNA,FOXO3,G6PD,KCND3,KCNE2,KCNK3,MEF2A,NPR2,NPTXR,OPRM1,PDE5A,PPARGC1A,PRKG1,RYR2,SLC9A1,SNTA1,STX1B,TBXA2R,TFF2,THRB,TMEM65,TNNI3K,TRPC3 |
| GO_REGULATION_OF_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 699 | 38 | ABAT,ATG5,ATP1A1,ATP2A1,ATP8A1,BEST3,CRY2,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GJC2,GRIA2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNS3,MEF2C,MYO5A,OPRM1,PPARGC1A,RYR2,SCN2A,SLC30A1,SLC9A1,SNTA1,STOM,SYT11,TREM2,TRPC3,TRPC6,WFS1,YWHAQ |
| GO_RESPONSE_TO_LIPID | 0.0e+00 | 0.0e+00 | 736 | 930 | 44 | ACP5,ADAM9,AGXT,ANKRD1,AQP1,AQP3,ATP1A1,ATP4B,BMP7,C5AR1,CD96,CRY2,CRYAB,FAM107A,FES,GIPR,GJB6,GNG2,INSIG2,LGALS9,LOX,LTK,MEF2C,MMP15,MT-ND3,OPRM1,P2RY4,PAM,PGRMC2,PPARGC1A,PTGIR,PTN,RBP4,S100A14,S100A8,SLPI,SOX9,SREBF2,TBXA2R,THRB,TICAM2,TREM2,WNT7B,WNT9A |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 736 | 973 | 45 | ABAT,ACSL3,ACTB,ADAM9,AGXT,ANKRD1,APLP1,AQP1,AQP3,ATP1A1,BMP7,BSG,CIB2,CRY2,CRYAB,EPHX1,FAM107A,FES,FLNA,G6PD,GNG2,GSN,LOX,LUM,MEF2C,MMP15,MT-CYB,MT-ND1,MT-ND3,NSG2,OPRM1,P2RY2,P2RY4,PALM,PAM,PGRMC2,PPARGC1A,PTN,RALB,RYR2,SLC9A1,TBXA2R,THRB,TRPC3,WNT7B |
| GO_RESPONSE_TO_TOXIC_SUBSTANCE | 0.0e+00 | 0.0e+00 | 736 | 539 | 32 | ABAT,ACTB,ADAM9,AQP1,BMP7,CBX8,CLDN18,CRYAB,EPHX1,EPHX2,FYN,G6PD,GJC2,GRIN2A,GSN,MGST3,MT-CYB,MT-ND4,OPRM1,PPARGC1A,PPP1R9A,RBP4,RHOB,S100A8,SLC30A1,SLC7A8,SNN,TBXA2R,TRPC6,TXNDC2,UNC79,XPA |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 1301 | 53 | ABAT,ADAM9,AGXT,ALDH1L2,AMDHD1,APOBEC3H,ASB11,BRSK2,C4BPB,CARNS1,CTSK,CYP3A5,ENPP4,EPHA4,FAF2,FBXL18,FBXO27,FLNA,FUCA1,FYN,GADL1,GGT7,GIPC1,GRIN2A,HGD,KCNE2,LUM,MAP1A,MOXD1,NAPSA,OVGP1,PDE5A,PIPOX,PLG,QPRT,RHBDD2,RNF149,RYBP,SLC9A1,SOX9,SPATA18,SYNPO2,THNSL2,TMEM259,TREM2,TTC3,UBQLNL,UGGT1,USP27X,USP9X,VLDLR,WFS1,XPNPEP1 |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 736 | 955 | 44 | ADGRA2,ANKRD1,BMP7,BRSK2,CLDN18,EPHA4,F11R,FBN1,FES,FLNA,FOXO6,FYN,G6PD,GJC2,ID2,ITPKA,KREMEN1,LMOD3,LRP4,LTK,MAPT,MEF2C,MELTF,MYO9A,NAP1L2,NDRG4,NPR2,OPRM1,P3H1,PDE5A,POU3F2,PPP1R9A,PREX1,PROX1,PTN,RAP2A,SOX9,STX1B,THRB,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR |
| GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 573 | 33 | ACTB,ATG5,ATP2A1,CLIP3,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GJC2,GRIA2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNS3,MEF2A,MEF2C,MYO5A,OPRM1,PPARGC1A,RYR2,SCN2A,SLC30A1,SLC9A1,SNTA1,STOM,TREM2,TRPC6,YWHAQ |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 736 | 1000 | 45 | ACVR1B,ANKRD1,BMP7,BTC,CD101,CD24,EPHA4,F11R,FES,FLNA,FOXO3,FOXO6,FYN,GJC2,HSF4,ID2,IL2RA,ITPKA,KITLG,LGALS9,LMOD3,LTK,MAPT,MEF2A,MEF2C,NAP1L2,NDRG4,OPRM1,P3H1,PDE5A,PPP1R9A,PPP2R3C,PREX1,PROM1,PROX1,PTN,SH3PXD2B,SOX9,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR,WNT7B,WNT9A |
| GO_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 486 | 30 | ATG5,ATP2A1,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GJC2,GRIA2,GRIN2A,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNS3,MEF2C,MYO5A,OPRM1,PPARGC1A,RYR2,SCN2A,SLC30A1,SLC9A1,SNTA1,STOM,TREM2,TRPC6,YWHAQ |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 736 | 1863 | 66 | ADAM9,ADGRV1,ADRA1B,AMOT,ANKRD1,APLP1,ARHGAP29,ARHGAP42,ARHGAP8,ARHGEF18,ARHGEF33,BMF,BMP7,BMP8B,BMT2,BTC,C1QTNF3,C5AR1,CAVIN4,CCL16,CD24,CGNL1,DMD,EPHA4,F11R,FLNA,FYN,GAB1,GIPR,GRIK2,IGF2,KITLG,L3MBTL1,LCK,LGALS9,LIMD1,MAP3K14,MAP3K9,MAP4K5,MAPT,MYO5A,MYO9A,NDRG4,NME5,NPR2,NRG4,OPRM1,OR2AT4,PDE5A,PREX1,RAP2A,RASD2,RASGRP4,RCAN2,RHOB,RHOU,RNF149,S100A8,SLC9A1,SOX9,TICAM2,TNK1,TREM2,TRIM62,WFS1,WNT7B |
| GO_CELLULAR_ION_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 736 | 683 | 36 | ACKR2,ADRA1B,ATG5,ATP1A1,ATP2A1,ATP4B,C5AR1,CD24,CIB2,DMD,EPHX2,FYN,GIPR,GRIK2,GRIN2A,HEPH,HPX,KCNK3,LCK,MCOLN2,MYO5A,P2RY2,P2RY4,PDE6B,PLCL1,PTGIR,RYR2,S100A8,SCARA5,SLC30A1,SLC9A1,TBXA2R,TFR2,TRPC3,TRPC6,WFS1 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 1962 | 68 | ABAT,ACAA2,ACOT4,ACP5,ACSL3,ACSS1,ADSS1,AGXT,AK8,ALDH1L2,AMDHD1,APOBEC3H,BSG,C1QTNF3,CARNS1,CHPF2,CHST1,CYP3A5,DAGLB,ECH1,ENPP4,EPHX1,EPHX2,FUCA1,G6PD,GADL1,GGT7,HGD,IGF2,INSIG2,ITPKA,LMF1,LUM,MACROD2,MDH1B,MGST3,MLXIPL,MOGAT3,MOXD1,MYO5A,NME5,NME9,NMNAT2,NMRK1,NPR2,OTOGL,PAM,PDE5A,PIPOX,PLCL1,PPARGC1A,PROX1,QPRT,RBP4,SCD5,SLC23A2,SLC27A1,SLC9A1,SREBF2,SULT1A2,THNSL2,TMEM86B,TPST2,TREM2,UGGT1,UGP2,VLDLR,VPS9D1 |
| GO_EMBRYONIC_ORGAN_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 736 | 434 | 28 | BMP7,CCDC103,CITED2,FBN1,FZD2,GJB6,ID2,IGF2,INSIG2,ITGA8,KITLG,KRT8,LRIG1,MEF2C,NDRG4,NKX3-2,OSR2,PLG,PROX1,RBP4,RYR2,SOX9,STRC,TUBB2B,VASH1,WHRN,WNT7B,WNT9A |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 736 | 1135 | 48 | ABAT,ACTB,AGXT,APLP1,AQP1,ATP4B,BMP7,BRSK2,BSG,C5AR1,CIB2,EPHA4,FAF2,FBN1,FBXO27,FLNA,FOXO3,FOXO6,FYN,GAB1,GNG2,GRIN2A,GSN,IGF2,INSIG2,MEF2C,MGST3,MT-CYB,MYO5A,NSG2,OPRM1,P2RY2,P2RY4,PALM,PPARGC1A,PTN,RALB,RHBDD2,RYR2,SLC27A1,SLC9A1,SOX9,SREBF2,TMEM259,TREM2,TRPC3,UGGT1,WFS1 |
| GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 0.0e+00 | 0.0e+00 | 736 | 561 | 32 | ABAT,ADAM9,ADGRV1,AQP1,AQP3,BMP7,BSG,CBX8,CRYAB,FABP4,FYN,G6PD,GIPR,GSN,ID2,KCNK3,KRT8,MAPT,MEF2A,MEF2C,MT-CO1,MT-CYB,PAM,PPARGC1A,RHOB,RYR2,S100A8,SLC30A1,SYT11,TFR2,TRPC3,TRPC6 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 736 | 1220 | 50 | ADAM9,ANKRD1,ATP8A1,BMF,BMP7,BTC,CIDEB,CLIP3,CLSTN2,CLTRN,EPHA4,FES,FLNA,FNBP1L,FOXO6,FYN,GPM6A,GSN,IGF2,ITPKA,KIAA1324,LMOD3,LRP4,LTK,MAPT,MELTF,NAP1L2,NDRG4,P3H1,PALM,PKIB,PPARGC1A,PPP1R9A,PREX1,PROM2,PROX1,PTN,RALB,RHOU,SH3PXD2B,SOX9,SREBF2,SYNPO2,TFR2,TRAK1,TREM2,TUBB2B,VLDLR,XPA,YWHAQ |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 736 | 1680 | 61 | ABAT,ACSL3,ADAM9,AGXT,ANKRD1,AQP1,ATG5,ATP8A1,BRSK2,C1QTNF3,C5AR1,CLTRN,CREG1,ENPP4,FAF2,FES,FLNA,FUCA1,GIPC1,GIPR,GSN,IGF2,ITGB6,KCNB1,KCNS3,LGALS9,LIN7B,LMF1,MCOLN2,MEF2C,MERTK,MYO5A,MYRIP,OPRM1,OSTF1,P2RY2,P2RY4,P3H1,PAM,PLG,PPP1R9A,QPCT,RALB,RASL10B,RBP4,S100A8,SLC17A7,SLC30A1,SLPI,SNPH,STBD1,STOM,STX1B,SYN1,SYNGR1,SYT11,SYTL3,TFF2,TFR2,TICAM2,TREM2 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 736 | 995 | 44 | ABAT,ACSL3,ACTB,ACVR1B,ADGRA2,AK8,AQP1,BMP7,C5AR1,EPHA4,FLNA,FYN,G6PD,GJC2,GRIN2A,GSN,HAPLN3,HDAC11,ID2,ITGA8,KCNK3,LAMC3,MACROD2,MAPT,MT-CO1,MT-ND4,NDRG4,NME5,PAM,POU3F2,PPARGC1A,PRKG1,PROX1,PTN,S100A8,SLC17A7,SNPH,SOX9,TREM2,UNC5C,VLDLR,WHRN,WNT7B,YWHAQ |
| GO_MUSCLE_CONTRACTION | 0.0e+00 | 0.0e+00 | 736 | 362 | 25 | ABAT,ADRA1B,ARHGAP42,ATP1A1,ATP2A1,CNN1,CRYAB,DAPK3,DES,DMD,EHD3,FLNA,KCND3,KCNE2,LMOD3,MYOM2,MYOT,PDE5A,PRKG1,RYR2,SLC9A1,SNTA1,SSPN,TBXA2R,TNNI3K |
| GO_RESPONSE_TO_METAL_ION | 0.0e+00 | 0.0e+00 | 736 | 364 | 25 | ABAT,ADAM9,ADGRV1,AQP1,AQP3,BSG,FABP4,G6PD,GIPR,GSN,ID2,KCNK3,MAPT,MEF2A,MEF2C,MT-CO1,MT-CYB,PAM,PPARGC1A,RYR2,S100A8,SLC30A1,SYT11,TFR2,TRPC3 |
| GO_CELL_PART_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 736 | 691 | 35 | ACTB,ARTN,BMP7,BRSK2,BSG,EFNA4,EPHA4,FYN,GAB1,GPM6A,ITPKA,LGI1,LGR6,LHX9,LRP4,MAP1A,MAPT,MATN2,MEF2A,MYO9A,MYOT,PARD6B,PICALM,POU3F2,PPP1R9A,PTN,RAP2A,SPTBN5,TRAK1,TRPC6,TUBB2B,UNC5C,USP9X,VLDLR,WNT7B |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 736 | 984 | 43 | ABAT,ACSL3,ACTB,ADAM9,ANKRD1,AQP1,ATG5,ATP2A1,ATP8A1,C1QTNF3,CLIP3,CLTRN,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GIPR,GJC2,KCNB1,KCNE2,LGALS9,MEF2A,MERTK,MYRIP,P2RY2,RASL10B,RBP4,RHOU,RYR2,S100A8,SEC16B,SLC9A1,SREBF2,STOM,STX1B,TFR2,TREM2,TRPC3,TRPC6,WFS1,YWHAQ |
| GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 736 | 260 | 21 | ABAT,ADRA1B,ARHGAP42,ATP1A1,ATP2A1,CNN1,DAPK3,DMD,EHD3,FLNA,FOXO3,G6PD,MEF2A,PDE5A,PPARGC1A,PRKG1,RYR2,SLC9A1,TBXA2R,TNNI3K,TRPC3 |
| GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 0.0e+00 | 0.0e+00 | 736 | 625 | 33 | ACSL3,ACTB,ARL5B,BMF,BSG,CD24,CLIP3,EHD3,F11R,FLNA,FYN,GRASP,GRIK2,GRIN2A,GSN,KCNB1,LGI1,LIN7B,LRP4,MYO5A,PALM,PEX16,PICALM,PTN,RAB40A,RAP2A,RILPL2,SH3PXD2B,STOM,STX1B,TM9SF2,TREM2,YWHAQ |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 0.0e+00 | 736 | 526 | 30 | ABCG8,ACSL3,ADSS1,AQP3,ATG5,BMP7,BMT2,CIB2,FAM107A,FES,FOXO3,FYN,G6PD,GIPR,GSN,KCNB1,KIAA1324,MT-CYB,OPRM1,P2RY2,P2RY4,PPARGC1A,PROX1,PTN,RALB,RASGRP4,SREBF2,TBXA2R,TMEM135,TRPC3 |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 1.0e-07 | 736 | 669 | 34 | AIF1L,ANKRD1,CGNL1,CLIP3,COL5A1,CRYAB,DAPK3,DES,EPPK1,FAM107A,FES,FLNA,GSN,KRT8,LMOD3,LOX,LUM,MAP1A,MAPT,MEF2A,MEF2C,MMP11,MYOM2,P4HA1,PFN4,PPP1R9A,PREX1,PROX1,RHOB,RHOU,SH3PXD2B,SLC9A1,SPTBN5,SYNPO2 |
| GO_MONOVALENT_INORGANIC_CATION_TRANSPORT | 0.0e+00 | 1.0e-07 | 736 | 537 | 30 | AQP1,ATP1A1,ATP2A1,ATP4B,COX8C,DMD,FHL1,FLNA,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,MT-CO1,MT-CO3,MT-CYB,MT-ND4,NDUFA4,SCN2A,SLC12A7,SLC17A7,SLC23A2,SLC28A3,SLC9A1,SNTA1,STOM,TREM2,VPS9D1 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 1.0e-07 | 736 | 1163 | 47 | ADAM9,ADGRA2,AKT3,AMOT,AQP1,ARHGEF18,BMP7,BRSK2,C5AR1,CITED2,COL5A1,DAAM1,DAPK3,EPHA4,F11R,FES,FLNA,FYN,FZD2,GAB1,ITPKA,LIMD1,LRP4,MAPT,MEF2C,MELTF,MYO9A,PALM,POU3F2,PPARGC1A,PPP1R9A,PREX1,PROX1,PTN,RAP2A,RHOB,RHOU,SOX9,TBXA2R,THRB,TMEM135,TRAK1,TREM2,TRPC6,TUBB2B,VASH1,WNT10A |
| GO_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 0.0e+00 | 1.0e-07 | 736 | 444 | 27 | ABAT,CLSTN2,EPHA4,FAM107A,FYN,GIPC1,GRIA2,GRIK2,GRIN2A,ITPKA,KCNB1,LGI1,MAP1A,MAPT,MEF2C,NPTXR,P2RY4,PLCL1,PLG,PPP1R9A,PTN,SLC30A1,STX1B,SYN1,SYNGR1,SYT11,TUBB2B |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 1.0e-07 | 736 | 1781 | 61 | ADAM9,APH1B,ARHGAP29,ARHGAP42,ARHGAP8,ATP2A1,ATP4B,C5AR1,CCL16,CD24,CDC20B,CIDEB,DMD,EHD3,EPHA4,F11R,FYN,FZD2,GRIN2A,GSN,IGF2,KCNE2,KITLG,LCK,LGALS9,LMF1,MAP3K14,MAP3K9,MAP4K5,MAPT,MEF2C,MMP15,MMP24,MYO9A,NOXA1,PDE5A,PERP,PICALM,PKIB,PLCL1,PPARGC1A,PPM1M,PPP1R9A,PPP2R3C,PREX1,PROX1,RALB,RASGRP4,RYR2,S100A8,SH3PXD2B,SLC27A1,SLC9A1,SNX18,TBC1D8B,TREM2,TRIM62,TRPC6,VLDLR,VPS9D1,WNT7B |
| GO_CIRCULATORY_SYSTEM_PROCESS | 0.0e+00 | 2.0e-07 | 736 | 554 | 30 | ABAT,ADRA1B,ARHGAP42,ATG5,ATP1A1,ATP2A1,DES,DMD,EHD3,EPHX2,F11R,FLNA,FYN,ID2,KCND3,KCNE2,KCNK3,MEF2A,NPR2,P2RY2,PDE5A,PRKG1,RASL10B,RYR2,SLC9A1,SNTA1,TBXA2R,THRB,TMEM65,TNNI3K |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 0.0e+00 | 2.0e-07 | 736 | 802 | 37 | ACSL3,ACTB,ASTN2,ATG5,ATP2A1,BRSK2,CLDN18,CLIP3,CLTRN,CRYAB,DMD,FES,FLNA,FYN,GRASP,GSN,KCNB1,LGALS9,LRP4,MAP1A,MAPT,MX2,MYO5A,NDRG4,PARD6B,PICALM,PTN,RALB,RHOU,RYR2,SEC16B,SREBF2,STOM,SYT11,TREM2,TRPC3,YWHAQ |
| GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS | 0.0e+00 | 2.0e-07 | 736 | 525 | 29 | ACKR2,ADRA1B,ATG5,ATP2A1,C5AR1,CD24,CIB2,DMD,EPHX2,FYN,GIPR,GRIK2,GRIN2A,KCNK3,LCK,MCOLN2,MYO5A,P2RY4,PDE6B,PLCL1,PTGIR,RYR2,S100A14,S100A8,SLC30A1,TBXA2R,TRPC3,TRPC6,WFS1 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 2.0e-07 | 736 | 1748 | 60 | ACAA2,ANKRD1,APH1B,AQP1,ARHGEF18,ATG5,BMF,BMP7,BMP8B,BTC,C5AR1,CCN6,CIDEB,CITED2,CLIP3,CRYAB,DAPK3,FLNA,FOXO3,FYN,G6PD,GRIK2,GRIN2A,GRK5,GSN,IFI6,IKZF3,IL31RA,KCNB1,KITLG,LCK,LGALS9,LOX,LTK,MAEL,MAP3K9,MAPT,MEF2C,MERTK,NKX3-2,NME5,PERP,PICALM,PPARGC1A,PREX1,PTN,RETREG1,RHOB,RYBP,S100A8,SLC9A1,SOX9,SYCP2,TMEM259,TREM2,UNC5C,USP27X,WFS1,WNT9A,YWHAQ |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 2.0e-07 | 736 | 1721 | 59 | ACTB,ADAM9,AGXT,ANKRD1,APLP1,AQP1,ARHGEF18,ATP1A1,BMP7,BSG,CGB7,CIB2,CITED2,CRY2,CRYAB,EPHA4,F11R,FAM107A,FBN1,FLNA,FOXO3,FOXO6,FYN,GAB1,GIPC1,GNG2,IGF2,INSIG2,ITGA8,LOX,LTBP1,MAPT,MEF2C,MMP15,MT-CYB,MT-ND3,MYO5A,NSG2,OPRM1,P2RY2,P2RY4,PALM,PAM,PGRMC2,PPARGC1A,PTN,RYR2,SLC27A1,SLC9A1,SOX9,SREBF2,TBXA2R,THRB,TOB1,TREM2,USP9X,WFIKKN1,WNT10A,WNT7B |
| GO_HEART_PROCESS | 0.0e+00 | 4.0e-07 | 736 | 295 | 21 | ADRA1B,ATG5,ATP1A1,ATP2A1,DES,DMD,EHD3,FLNA,FYN,KCND3,KCNE2,KCNK3,MEF2A,NPR2,PDE5A,RYR2,SLC9A1,SNTA1,THRB,TMEM65,TNNI3K |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 4.0e-07 | 736 | 1567 | 55 | ACP5,ADAM9,ANKRD1,APOBEC3H,ARID5A,ATG5,ATP4B,BPIFB1,C4BPB,C5AR1,CCL16,CD24,CD96,CTSK,DAPK3,FABP4,FLNA,FYN,GJB6,GPM6A,GSN,HMCN1,HPX,IFI6,IKZF3,IL10RB,IL2RA,IL31RA,IRF6,KLHL6,KRT8,LAG3,LGALS9,MACROD2,MAP3K14,MCOLN2,MEF2C,MUC3A,MX2,OPRM1,PPARGC1A,PPP2R3C,PTGIR,S100A14,S100A8,SIGLEC10,SLPI,SYT11,TBXA2R,TENT5A,TICAM2,TREM2,TRIM62,VWCE,WFS1 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 4.0e-07 | 736 | 1880 | 62 | ACTB,ACVR1B,ADAM9,ADRA1B,ARHGAP8,ATG5,BMP7,BMP8B,C5AR1,CCL16,CCNI2,CD24,CDC20B,CLIP3,CRY2,DMD,EPHA4,FABP4,FAM107A,FYN,G6PD,GJC2,GRIK2,HPX,IGF2,IL31RA,KITLG,LGALS9,LOX,LRP4,MAP3K14,MAP3K9,MAP4K5,MAPT,MLXIPL,NAP1L2,NDRG4,OPRM1,OR2AT4,P3H1,PDE5A,PKIB,PLCL1,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,PTN,RALB,RAP2A,RASD2,RCAN2,RNF149,SLC27A1,SNTA1,SOX9,TREM2,TRPC6,VLDLR,WFS1,WNT7B |
| GO_DENDRITE_DEVELOPMENT | 0.0e+00 | 5.0e-07 | 736 | 244 | 19 | BMP7,EPHA4,FOXO6,FYN,ITPKA,LRP4,MAP1A,MATN2,MEF2A,MEF2C,PICALM,PPP1R9A,PREX1,PRKG1,PTN,RAP2A,TRAK1,TRPC6,VLDLR |
| GO_REGULATION_OF_BLOOD_CIRCULATION | 0.0e+00 | 5.0e-07 | 736 | 299 | 21 | ADRA1B,ARHGAP42,ATP1A1,ATP2A1,DES,DMD,EHD3,FLNA,KCND3,KCNE2,KCNK3,MEF2A,NPR2,PDE5A,RYR2,SLC9A1,SNTA1,TBXA2R,THRB,TMEM65,TNNI3K |
| GO_REGULATION_OF_MUSCLE_CONTRACTION | 0.0e+00 | 6.0e-07 | 736 | 172 | 16 | ABAT,ADRA1B,ARHGAP42,ATP1A1,ATP2A1,CNN1,DAPK3,DMD,EHD3,FLNA,PDE5A,PRKG1,RYR2,SLC9A1,TBXA2R,TNNI3K |
| GO_AXON_DEVELOPMENT | 0.0e+00 | 6.0e-07 | 736 | 523 | 28 | ACTB,ARTN,BMP7,BRSK2,BSG,EFNA4,EPHA4,FYN,GAB1,KREMEN1,LGI1,LGR6,LHX9,LRP4,MAP1A,MAPT,MATN2,MYOT,PARD6B,PICALM,POU3F2,PTN,SPTBN5,TRAK1,TUBB2B,UNC5C,USP9X,VLDLR |
| GO_IMPORT_INTO_CELL | 0.0e+00 | 6.0e-07 | 736 | 810 | 36 | ACKR2,ACSL3,ACTB,AMPH,APLP1,ATP1A1,ATP4B,CLIP3,EHBP1,ELMO1,FNBP1L,FYN,GSN,HHIPL1,HPX,IGLV1-51,KCNE2,LRP4,MX2,PICALM,PROM2,RHOU,SCARA5,SLC12A7,SLC17A7,SLC27A1,SLC30A1,SLC9A1,SNX18,STON2,STX1B,SYT11,TFR2,TREM2,VLDLR,WIPF3 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 736 | 1724 | 58 | ACVR1B,ADAM9,ADRA1B,ARHGAP8,ASB11,BMP7,BMP8B,C4BPB,C5AR1,CCL16,CD24,CDC20B,CIDEB,CLIP3,CTIF,EPHA4,FAM107A,FYN,GRIN2A,GSN,HPX,IGF2,IL31RA,KCNE2,KITLG,LCK,LGALS9,LRP4,MAP3K14,MAP3K9,MAP4K5,MAPT,MELTF,NAP1L2,NDRG4,OPRM1,OR2AT4,PDE5A,PERP,PICALM,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,RALB,RAP2A,RASD2,S100A8,SLC27A1,SOX9,TFR2,TMEM259,TREM2,TRPC6,VLDLR,WFS1,WNT7B |
| GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 6.0e-07 | 736 | 335 | 22 | ANKRD1,AQP1,AQP3,ATG5,ATP1A1,BMT2,CIB2,F11R,FAM107A,FES,FYN,KCNB1,KIAA1324,MAP3K14,P2RY2,P2RY4,PIEZO2,PTN,RALB,SLC9A1,SOX9,SREBF2 |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 7.0e-07 | 736 | 562 | 29 | ANKRD1,BMP7,EPHA4,F11R,FES,FLNA,FOXO6,FYN,GJC2,ID2,ITPKA,LMOD3,LTK,MAPT,MEF2C,NAP1L2,NDRG4,OPRM1,P3H1,PDE5A,PPP1R9A,PREX1,PROX1,PTN,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 7.0e-07 | 736 | 1051 | 42 | ACTB,ACVR1B,ADAM9,ADGRA2,APH1B,ARHGEF18,BMP7,BMP8B,BTC,CITED2,COL4A4,EFNA4,ELMO1,EPHA4,F11R,FBN1,FES,FOXO3,FOXO6,FYN,GAB1,GIPC1,IFI6,IGF2,IL31RA,ITGA8,LCK,LOX,LTBP1,LTK,MERTK,NDRG4,NPR2,NRG4,PTGIR,PTN,RASGRP4,SOX9,TNK1,TOB1,USP9X,WFIKKN1 |
| GO_SENSORY_PERCEPTION | 0.0e+00 | 8.0e-07 | 736 | 978 | 40 | ADGRV1,BBS9,C5AR1,CNTN5,CRYGS,FYN,FZD2,GABRR2,GJB6,GRIN2A,HMCN1,HSF4,LAMC3,LRIG1,LUM,MMP24,MYO5A,MYO9A,NXNL2,OPRM1,OR10G4,OR10Z1,OR2AT4,OR2M3,OR2T33,OR4K17,OR52I1,OTOGL,PDE6B,PIEZO2,RBP4,RETREG1,RGS9BP,SLC9A1,STRC,TAS1R3,TECTA,THRB,WFS1,WHRN |
| GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 0.0e+00 | 9.0e-07 | 736 | 373 | 23 | ADAM19,BSG,CAPNS2,COL4A4,COL5A1,CTSK,F11R,FBN1,ITGA8,ITGB6,LAMC3,LOX,LUM,MATN4,MELTF,MMP11,MMP15,MMP24,NID2,P4HA1,PLG,SH3PXD2B,SOX9 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 1.0e-06 | 736 | 1107 | 43 | ACVR1B,ADAM9,ADGRA2,AKT3,AMOT,ATP1A1,ATP2A1,ATP8A1,BMP7,BTC,C5AR1,CCDC65,CITED2,DAPK3,EPPK1,FAM107A,FES,FLNA,FOXO3,GAB1,KITLG,LGALS9,LGR6,MEF2C,NDRG4,NRG4,PARD6B,PLVAP,PPARGC1A,PREX1,PRKG1,PROX1,PTN,RAP2A,RHOB,RYR2,S100A14,SOX9,TBXA2R,TREM2,TUBB2B,UNC5C,VASH1 |
| GO_SENSORY_ORGAN_MORPHOGENESIS | 0.0e+00 | 1.0e-06 | 736 | 258 | 19 | BMP7,COL5A1,FBN1,FZD2,GJB6,INSIG2,ITGA8,LRIG1,NKX3-2,OSR2,PROM1,PROX1,PTN,RBP4,SOX9,STRC,THRB,WHRN,WNT9A |
| GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 1.1e-06 | 736 | 346 | 22 | ATG5,ATP2A1,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GJC2,GRIA2,GRIN2A,KCNE2,MEF2C,MYO5A,OPRM1,PPARGC1A,RYR2,SLC30A1,SLC9A1,SNTA1,STOM,TREM2 |
| GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 1.2e-06 | 736 | 687 | 32 | ANKRD1,ATG5,BMP7,BRSK2,EPHA4,FES,FNBP1L,FOXO6,FYN,GPM6A,ITPKA,KREMEN1,LRP4,LTK,MAPT,MEF2C,MYO9A,NDRG4,P3H1,PALM,POU3F2,PPP1R9A,PREX1,PROM2,PTN,RAP2A,STX1B,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 1.2e-06 | 736 | 687 | 32 | ABAT,ACTB,C4BPB,COL5A1,EHD3,ENPP4,EPHA4,EPPK1,F11R,FLNA,FYN,GIPR,GNG2,GRIN2A,GSN,KREMEN1,LCK,LGR6,LOX,MATN2,MERTK,OPRM1,PLG,PRKG1,PTN,S100A8,SIGLEC10,SYT11,TBXA2R,TRPC3,TRPC6,VASH1 |
| GO_EMBRYONIC_ORGAN_MORPHOGENESIS | 0.0e+00 | 1.5e-06 | 736 | 294 | 20 | BMP7,CCDC103,FBN1,FZD2,GJB6,ID2,INSIG2,ITGA8,LRIG1,MEF2C,NDRG4,NKX3-2,OSR2,PROX1,RBP4,RYR2,SOX9,STRC,WHRN,WNT9A |
| GO_REGULATION_OF_NEURON_DIFFERENTIATION | 0.0e+00 | 1.6e-06 | 736 | 659 | 31 | ANKRD1,BMP7,BRSK2,EPHA4,FES,FOXO6,FYN,ID2,ITPKA,KREMEN1,LRP4,LTK,MAPT,MEF2C,MYO9A,NAP1L2,NDRG4,P3H1,POU3F2,PPP1R9A,PREX1,PROX1,PTN,RAP2A,SOX9,STX1B,THRB,TRAK1,TRPC6,TUBB2B,VLDLR |
| GO_HEART_DEVELOPMENT | 0.0e+00 | 1.7e-06 | 736 | 589 | 29 | ANKRD1,ATG5,BMP7,CCDC103,CITED2,COL5A1,FBN1,FZD2,G6PD,ID2,IRX4,LOX,LTBP1,MEF2A,MEF2C,MYOM2,NDRG4,NFATC1,PAM,PROX1,PTN,RBP4,RIPPLY3,RYR2,SALL4,SH3PXD2B,SLC9A1,SOX9,TMEM65 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 1.7e-06 | 736 | 1741 | 57 | ACOT4,AGXT,ARL4C,ARL5B,ATP2A1,BRSK2,CD24,CRYAB,DENND2A,ECH1,EHD3,EPHX2,FAF2,FES,FLNA,FNBP1L,FYN,GIPC1,GRASP,KCNB1,LCA5L,LGALS9,LMF1,MAP1A,MAPT,MX2,MYO5A,MYRIP,NDRG4,NSG2,PEX16,PICALM,PIPOX,PLEKHA8,RAB30,RAB36,RAB40A,RAB6B,RHOB,RHOU,RILPL2,SEC16B,SEC31B,SNX18,SPTBN5,SREBF2,STBD1,STOM,STX1B,SYNGR1,SYTL3,TBC1D8B,TICAM2,TRAK1,TUBA1A,USP9X,YWHAQ |
| GO_RESPONSE_TO_ANTIBIOTIC | 0.0e+00 | 2.2e-06 | 736 | 331 | 21 | ABAT,ADAM9,AQP1,CBX8,CLDN18,CRYAB,FYN,G6PD,GRIN2A,GSN,MEF2C,MT-CYB,MT-ND4,OPRM1,RBP4,RHOB,S100A8,SLC9A1,TBXA2R,TRPC6,UNC79 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 2.5e-06 | 736 | 1318 | 47 | ABAT,ABCG8,ACP5,AMOT,ARHGAP42,ATP1A1,BMP7,C1QTNF3,CD24,CD96,CLDN18,COL5A1,CTSK,EPHA4,EPPK1,FBN1,G6PD,H4C15,ID2,KREMEN1,LAG3,LGALS9,LIMD1,LRP4,MEF2C,MERTK,NFATC1,NKX3-2,NPR2,PDE5A,PLCL1,PLG,PRKG1,PTN,RBP4,SOX9,STX1B,SYT11,TBXA2R,TFF2,THRB,TOB1,TREM2,TRIM62,TRPC6,VASH1,WNT9A |
| GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 0.0e+00 | 3.0e-06 | 736 | 369 | 22 | ACKR2,ADRA1B,ATG5,C5AR1,CD24,CIB2,DMD,FYN,GIPR,GRIN2A,KCNK3,LCK,MCOLN2,MYO5A,P2RY4,PDE6B,PLCL1,PTGIR,RYR2,TBXA2R,TRPC3,TRPC6 |
| GO_SENSORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 3.0e-06 | 736 | 369 | 22 | BMP7,COL5A1,CRYAB,CRYGS,FBN1,GPM6A,HSF4,LAMC3,MERTK,MYOM2,OSR2,PDE6B,PROM1,PROX1,PTN,RBP4,SH3PXD2B,SLC17A7,SOX9,THRB,WNT7B,WNT9A |
| GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 0.0e+00 | 3.4e-06 | 736 | 504 | 26 | ANKRD1,BMP7,BRSK2,EPHA4,FES,FOXO6,FYN,ITPKA,KREMEN1,LRP4,LTK,MAPT,MEF2C,MYO9A,NDRG4,P3H1,POU3F2,PPP1R9A,PREX1,PTN,RAP2A,STX1B,TRAK1,TRPC6,TUBB2B,VLDLR |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 1.0e-07 | 3.7e-06 | 736 | 1208 | 44 | ACTB,ADAM9,ANKRD1,APLP1,AQP1,BMP7,BRSK2,CBX8,CIB2,CLTRN,EPHA4,FBN1,FES,FLNA,FOXO3,FOXO6,FYN,GAB1,GJB6,GNG2,IGF2,KCNB1,LTK,MAPT,MEF2C,MLXIPL,MYO5A,NSG2,OPRM1,P2RY2,P2RY4,PALM,PPARGC1A,PTN,RHOB,RYR2,SLC9A1,SOX9,TBXA2R,TICAM2,TREM2,TRPC6,WNT7B,WNT9A |
| GO_TAXIS | 1.0e-07 | 4.0e-06 | 736 | 652 | 30 | ACKR2,ADGRA2,AMOT,ARTN,BMP7,BSG,C5AR1,CCL16,EFNA4,EPHA4,FES,FYN,GAB1,ID2,LGALS9,LGI1,LGR6,LHX9,LOX,MATN2,MYOT,PREX1,PTN,S100A14,S100A8,SPTBN5,TREM2,TUBB2B,UNC5C,VLDLR |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1.0e-07 | 4.1e-06 | 736 | 1429 | 49 | ADAM9,APH1B,ARHGAP29,ARHGAP42,ARHGAP8,ATP4B,C5AR1,CCL16,CD24,CDC20B,CIDEB,EPHA4,F11R,FYN,GRIN2A,GSN,IGF2,KITLG,LCK,LGALS9,LMF1,MAP3K14,MAP3K9,MAP4K5,MAPT,MEF2C,MMP15,MMP24,MYO9A,NOXA1,PDE5A,PERP,PICALM,PKIB,PPM1M,PPP1R9A,PPP2R3C,PREX1,PROX1,RALB,RASGRP4,S100A8,SH3PXD2B,SLC27A1,SNX18,TBC1D8B,VLDLR,VPS9D1,WNT7B |
| GO_SECOND_MESSENGER_MEDIATED_SIGNALING | 1.0e-07 | 4.3e-06 | 736 | 443 | 24 | ACKR2,ADRA1B,APLP1,AQP1,DMD,GIPR,GNG2,GRIN2A,MAPT,MYO5A,NFATC1,NPR2,OPRM1,PDE5A,PPP1R9A,PRKG1,PTGIR,RASD2,RCAN2,RYR2,SLC9A1,SOX9,TBXA2R,TREM2 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 1.0e-07 | 4.6e-06 | 736 | 928 | 37 | ANKRD1,BMP7,BRSK2,CLSTN2,EPHA4,FES,FLNA,FOXO6,FYN,FZD2,GJC2,ID2,ITPKA,KREMEN1,LRP4,LTK,MAPT,MEF2C,MYO9A,NAP1L2,NDRG4,OPRM1,P3H1,POU3F2,PPP1R9A,PREX1,PROX1,PTN,RAP2A,SOX9,STX1B,THRB,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR |
| GO_HEAD_DEVELOPMENT | 1.0e-07 | 5.1e-06 | 736 | 774 | 33 | ABAT,ACSL3,ACTB,AK8,AQP1,BMP7,C5AR1,FLNA,FYN,G6PD,GJC2,GRIN2A,ID2,ITGA8,KCNK3,MACROD2,MT-CO1,MT-ND4,NDRG4,NME5,OSR2,POU3F2,PPARGC1A,PRKG1,PROX1,PTN,SLC17A7,SNPH,SOX9,UNC5C,WHRN,WNT7B,YWHAQ |
| GO_SYNAPSE_ORGANIZATION | 1.0e-07 | 5.1e-06 | 736 | 414 | 23 | ACTB,BSN,C5AR1,CLSTN2,CNTN5,EPHA4,FYN,GPM6A,ITPKA,LRP4,MAPT,MEF2C,MYO5A,MYOT,PALM,PCDHB3,PCDHB6,PPP1R9A,PTN,SYN1,TREM2,TUBA1A,WNT7B |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 1.0e-07 | 5.1e-06 | 736 | 1267 | 45 | ACAA2,ATG5,BMF,BMP7,BTC,CCDC8,CIDEB,CLIP3,CLTRN,DAPK3,EHD3,F11R,FAM107A,FES,FLNA,GSN,IGF2,KIAA1324,L3MBTL1,LMOD3,MAP1A,MAP9,MAPT,MEF2C,NAP1L2,PAM,PFN4,PKIB,PPARGC1A,PPP1R9A,PREX1,PROX1,RALB,RHOB,RHOU,S100A8,SH3PXD2B,SLC9A1,SPTBN5,SREBF2,SYNPO2,SYT11,TMEM135,TREM2,YWHAQ |
| GO_RESPONSE_TO_ETHANOL | 1.0e-07 | 5.7e-06 | 736 | 132 | 13 | ABAT,CLDN18,FYN,G6PD,GRIN2A,GSN,MT-CYB,MT-ND4,OPRM1,RBP4,S100A8,TBXA2R,UNC79 |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1.0e-07 | 5.9e-06 | 736 | 1146 | 42 | ACSL3,ACVR1B,ADAM9,ADRA1B,ARHGAP8,BMP7,BMP8B,C5AR1,CCL16,CD24,CLIP3,EPHA4,FYN,HPX,IGF2,IL31RA,KITLG,LGALS9,LRP4,MAP3K14,MAP3K9,MAP4K5,MAPT,MEF2C,MLXIPL,NDRG4,OPRM1,OR2AT4,PDE5A,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,RALB,RAP2A,SLC27A1,SOX9,TREM2,TRPC6,VLDLR,WNT7B |
| GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 1.0e-07 | 6.3e-06 | 736 | 387 | 22 | ATP1A1,ATP2A1,DAPK3,F11R,FAM107A,FES,FLNA,GSN,LMOD3,MEF2C,PAM,PFN4,PPP1R9A,PREX1,PROX1,RHOB,RHOU,RYR2,SH3PXD2B,SLC9A1,SPTBN5,SYNPO2 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 1.0e-07 | 6.3e-06 | 736 | 1454 | 49 | ACTB,ADAM9,ANKRD1,APLP1,AQP1,ARHGEF18,ATP1A1,BMP7,CGB7,CIB2,CITED2,CRY2,EPHA4,F11R,FAM107A,FBN1,FLNA,FOXO3,FOXO6,FYN,GAB1,GIPC1,GNG2,IGF2,ITGA8,LOX,LTBP1,MAPT,MEF2C,MT-ND3,MYO5A,NSG2,OPRM1,P2RY2,P2RY4,PALM,PGRMC2,PPARGC1A,PTN,RYR2,SLC27A1,SLC9A1,SOX9,THRB,TOB1,TREM2,USP9X,WFIKKN1,WNT10A |
| GO_BEHAVIOR | 1.0e-07 | 6.9e-06 | 736 | 598 | 28 | ABAT,APH1B,ATP8A1,EPHA4,FOXO6,FYN,GRIK2,GRIN2A,ID2,ITGA8,MAP1A,MAPT,MEF2C,MYO5A,NDRG4,OPRM1,PICALM,PRLHR,PTN,RASD2,SCN2A,SLC17A7,SYT11,TAFA2,THRB,UNC79,VLDLR,WFS1 |
| GO_REGULATION_OF_CELL_MORPHOGENESIS | 1.0e-07 | 6.9e-06 | 736 | 491 | 25 | ARHGEF18,BRSK2,DAPK3,EPHA4,F11R,FES,FLNA,FYN,ITPKA,LIMD1,LRP4,MAPT,MELTF,MYO9A,PALM,POU3F2,PPP1R9A,PREX1,PTN,RAP2A,RHOB,RHOU,TRAK1,TRPC6,TUBB2B |
| GO_REGULATION_OF_SECRETION | 1.0e-07 | 6.6e-06 | 736 | 824 | 34 | ABAT,ACSL3,ADAM9,ANKRD1,AQP1,ATG5,BRSK2,C1QTNF3,CLTRN,FES,GIPC1,GIPR,KCNB1,KCNS3,LGALS9,MEF2C,MYRIP,OPRM1,P2RY2,P2RY4,P3H1,PAM,PPP1R9A,RALB,RASL10B,RBP4,S100A8,SLC30A1,STX1B,SYN1,SYT11,TFF2,TFR2,TREM2 |
| GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 1.0e-07 | 7.0e-06 | 736 | 327 | 20 | ACSL3,ACTB,BSG,CLIP3,EHD3,F11R,FLNA,GRASP,GRIN2A,KCNB1,LGI1,LIN7B,MYO5A,PALM,PICALM,RAB40A,RAP2A,RILPL2,STX1B,TREM2 |
| GO_PROTEOLYSIS | 1.0e-07 | 7.0e-06 | 736 | 1779 | 56 | ACTB,ADAM19,ADAM9,ADAMTS15,ADGRV1,APH1B,AQP1,BRSK2,CAPN5,CAPNS2,CIDEB,CNDP1,CPA6,CRYAB,CTSK,EPHA4,FAF2,FBXL18,FBXO27,FYN,GGT7,GIPC1,GRIN2A,GSN,IFI6,KCNE2,LCK,LGALS9,MAP1A,MAPT,MELTF,MMP11,MMP15,MMP24,NAPSA,PERP,PICALM,PLG,RHBDD2,RNF149,RYBP,S100A8,SLPI,TMEM259,TREM2,TTC3,UBQLNL,UGGT1,USP27X,USP9X,VASH1,WFDC3,WFIKKN1,WFS1,WNT9A,XPNPEP1 |
| GO_RESPONSE_TO_MECHANICAL_STIMULUS | 1.0e-07 | 7.2e-06 | 736 | 211 | 16 | ADGRV1,ANKRD1,AQP1,ATP1A1,DMD,F11R,FYN,MAP3K14,PIEZO2,PTN,RYR2,SLC9A1,SOX9,STRC,WHRN,XPA |
| GO_EPITHELIUM_DEVELOPMENT | 2.0e-07 | 8.8e-06 | 736 | 1296 | 45 | ACVR1B,ADAM9,AQP3,ASTN2,BMP7,BRSK2,CCDC103,CD24,CITED2,COL5A1,CRYGS,CTSK,DAAM1,EPHA4,EPPK1,F11R,FLNA,FZD2,ID2,IL31RA,IRF6,KRT38,KRT8,KRTAP5-11,LRP4,MEF2C,MYO5A,MYO9A,NDRG4,NKX3-2,PERP,PROM1,PROX1,PTN,RHOB,RILPL2,RYR2,SALL4,SETSIP,SOX9,STRC,THRB,WHRN,WNT10A,WNT7B |
| GO_CARDIAC_MUSCLE_CONTRACTION | 2.0e-07 | 1.1e-05 | 736 | 141 | 13 | ADRA1B,ATP1A1,ATP2A1,DMD,EHD3,FLNA,KCND3,KCNE2,PDE5A,RYR2,SLC9A1,SNTA1,TNNI3K |
| GO_CELL_ACTIVATION | 2.0e-07 | 1.1e-05 | 736 | 1442 | 48 | ABAT,ACTB,ADAM9,ATG5,ATP8A1,C5AR1,CD24,CD79A,CREG1,DNASE1L3,ENPP4,F11R,FAF2,FES,FLNA,FUCA1,FYN,GNG2,GSN,ID2,IGF2,IKZF3,IL21R,IL2RA,IL31RA,LAG3,LCK,LGALS9,MAPT,MEF2C,MERTK,OSTF1,PDE5A,PPP2R3C,PREX1,PRKG1,QPCT,S100A8,SLPI,STBD1,STOM,SYNGR1,SYT11,TICAM2,TREM2,TRPC3,TRPC6,ZNF3 |
| GO_CELLULAR_RESPONSE_TO_DRUG | 2.0e-07 | 1.1e-05 | 736 | 436 | 23 | ACTB,ADSS1,ANKRD1,AQP1,CBX8,CIB2,FLNA,FYN,GNG2,KCNE2,MEF2C,NSG2,OPRM1,P2RY2,P2RY4,PALM,PPARGC1A,RAP2A,RHOB,RNF149,RYR2,SOX9,TRPC6 |
| GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | 2.0e-07 | 1.2e-05 | 736 | 248 | 17 | ADAM9,ANKRD1,ARHGEF18,CITED2,F11R,FBN1,FYN,GIPC1,ITGA8,LOX,LTBP1,MEF2C,PPARGC1A,SOX9,USP9X,WFIKKN1,WNT10A |
| GO_ACTIN_FILAMENT_BASED_MOVEMENT | 2.0e-07 | 1.3e-05 | 736 | 143 | 13 | ATP1A1,ATP2A1,DES,DMD,FLNA,FNBP1L,KCND3,KCNE2,MYO5A,RYR2,SLC9A1,SNTA1,WIPF3 |
| GO_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS | 2.0e-07 | 1.3e-05 | 736 | 221 | 16 | ADGRV1,BBS9,CRYGS,GABRR2,HMCN1,HSF4,LAMC3,LUM,MYO5A,MYO9A,NXNL2,PDE6B,RBP4,RGS9BP,WFS1,WHRN |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 2.0e-07 | 1.3e-05 | 736 | 974 | 37 | ADAM9,ADRA1B,ARHGAP8,ARTN,BMP7,BMP8B,BTC,C5AR1,CCL16,CD24,CRYAB,EPHA4,FYN,GRIK2,IGF2,IL2RA,IL31RA,KITLG,LGALS9,MAP3K14,MAP3K9,MAP4K5,MEF2A,MEF2C,NDRG4,NRG4,OPRM1,OR2AT4,PDE5A,PLVAP,RAP2A,RASGRP4,RNF149,SOX9,SPTBN5,TREM2,WNT7B |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 2.0e-07 | 1.3e-05 | 736 | 547 | 26 | ANKRD1,BMP7,CLSTN2,EPHA4,FES,FLNA,FOXO6,FYN,GJC2,ID2,ITPKA,LTK,MAPT,MEF2C,NAP1L2,NDRG4,OPRM1,P3H1,PPP1R9A,PROX1,PTN,TRAK1,TREM2,TRPC6,TUBB2B,VLDLR |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 2.0e-07 | 1.4e-05 | 736 | 1823 | 56 | ACSL3,ACTB,ACVR1B,ADAM9,ADRA1B,ARHGAP8,BMP7,BMP8B,C5AR1,CCDC8,CCL16,CCNI2,CD24,CLIP3,CRY2,DMD,EPHA4,FABP4,FYN,GJC2,GRIK2,HPX,IGF2,IL31RA,KITLG,LGALS9,LOX,LRP4,MAP3K14,MAP3K9,MAP4K5,MAPT,MEF2C,MLXIPL,NDRG4,OPRM1,OR2AT4,PDE5A,PKIB,PLCL1,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,PTN,RALB,RAP2A,RCAN2,RNF149,SLC27A1,SOX9,TREM2,TRPC6,VLDLR,WNT7B |
| GO_CARDIAC_CONDUCTION | 3.0e-07 | 1.6e-05 | 736 | 146 | 13 | ATP1A1,ATP2A1,EHD3,FLNA,KCND3,KCNE2,KCNK3,MEF2A,NPR2,RYR2,SLC9A1,TMEM65,TNNI3K |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 3.0e-07 | 1.6e-05 | 736 | 1026 | 38 | ADAM9,ADGRV1,ADRA1B,ANKRD1,ARHGAP8,BMF,BTC,C5AR1,CCL16,CD24,EPHA4,F11R,FLNA,FYN,GAB1,GIPR,IGF2,KITLG,LCK,LGALS9,MAP3K14,MAP3K9,MAP4K5,NDRG4,NPR2,NRG4,OPRM1,OR2AT4,PDE5A,RASD2,RASGRP4,S100A8,SLC9A1,SOX9,TICAM2,TREM2,TRIM62,WNT7B |
| GO_EMBRYO_DEVELOPMENT | 3.0e-07 | 1.7e-05 | 736 | 1029 | 38 | ACVR1B,AMOT,BMP7,CCDC103,CCDC24,CITED2,COL5A1,FBN1,FZD2,GJB6,ID2,IGF2,INSIG2,ITGA8,KITLG,KRT8,LRIG1,LRP4,MEF2C,MMP15,MT-ND4,NDRG4,NKX3-2,OSR2,PLG,PROX1,RBP4,RIPPLY3,RYR2,SALL4,SLC30A1,SOX9,STRC,TUBB2B,VASH1,WHRN,WNT7B,WNT9A |
| GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS | 3.0e-07 | 1.7e-05 | 736 | 483 | 24 | ABAT,ACP5,ACTB,ADGRV1,AQP1,AQP3,CIB2,CLDN18,CTSK,FABP4,LIPA,MLXIPL,NAPSA,NXNL2,PLCL1,PPARGC1A,PROM1,PTH2R,RBP4,SLC27A1,SOX9,TFF2,WFS1,WHRN |
| GO_EMBRYONIC_MORPHOGENESIS | 3.0e-07 | 1.7e-05 | 736 | 592 | 27 | AMOT,BMP7,CCDC103,COL5A1,FBN1,FZD2,GJB6,ID2,IGF2,INSIG2,ITGA8,LRIG1,LRP4,MEF2C,MMP15,NDRG4,NKX3-2,OSR2,PROX1,RBP4,RYR2,SALL4,SOX9,STRC,WHRN,WNT7B,WNT9A |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 3.0e-07 | 1.8e-05 | 736 | 1247 | 43 | ACVR1B,ADAM9,ADRA1B,ARHGAP8,BMP7,BMP8B,C5AR1,CCL16,CD24,CDC20B,CLIP3,EPHA4,FAM107A,FYN,HPX,IGF2,IL31RA,KITLG,LGALS9,LRP4,MAP3K14,MAP3K9,MAP4K5,NAP1L2,NDRG4,OPRM1,OR2AT4,PDE5A,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,RALB,RAP2A,RASD2,SLC27A1,SOX9,TREM2,TRPC6,VLDLR,WFS1,WNT7B |
| GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION | 4.0e-07 | 2.0e-05 | 736 | 82 | 10 | ADRA1B,ATP1A1,ATP2A1,DMD,EHD3,FLNA,PDE5A,RYR2,SLC9A1,TNNI3K |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 4.0e-07 | 2.0e-05 | 736 | 1037 | 38 | ABAT,ACSL3,ACTB,ADAM9,ANKRD1,ASTN2,ATG5,BRSK2,C1QTNF3,CLDN18,CLIP3,CLTRN,FLNA,FYN,GIPR,GRASP,GSN,KCNB1,KCNS3,LGALS9,LRP4,MAP1A,MAPT,MYRIP,OPRM1,P3H1,PAM,PICALM,PTN,RALB,RBP4,RHOU,SEC16B,SREBF2,STOM,SYT11,TREM2,YWHAQ |
| GO_SKELETAL_SYSTEM_DEVELOPMENT | 4.0e-07 | 2.1e-05 | 736 | 526 | 25 | ACP5,BMP7,BMP8B,CLDN18,CTSK,FBN1,HAPLN3,IGF2,INSIG2,LOX,LUM,MATN2,MATN4,MEF2C,NKX3-2,NPR2,OSR2,P3H1,RBP4,SH3PXD2B,SOX9,TTC9,WFIKKN1,WNT7B,WNT9A |
| GO_MULTICELLULAR_ORGANISMAL_SIGNALING | 4.0e-07 | 2.3e-05 | 736 | 204 | 15 | ATP1A1,ATP2A1,EHD3,FLNA,GRIK2,KCND3,KCNE2,KCNK3,MEF2A,NPR2,RYR2,SCN2A,SLC9A1,TMEM65,TNNI3K |
| GO_STRIATED_MUSCLE_CONTRACTION | 4.0e-07 | 2.3e-05 | 736 | 177 | 14 | ADRA1B,ATP1A1,ATP2A1,DMD,EHD3,FLNA,KCND3,KCNE2,LMOD3,PDE5A,RYR2,SLC9A1,SNTA1,TNNI3K |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 5.0e-07 | 2.3e-05 | 736 | 1670 | 52 | ACTB,ACVR1B,AQP3,ATG5,BPIFB1,C4BPB,C5AR1,CD101,CD24,CD79A,CD96,CLDN18,CTSK,DNASE1L3,ELMO1,FBN1,FES,FOXO3,FYN,GSN,H4C15,HPX,ID2,IGF2,IGLV1-51,IKZF3,IL2RA,IL31RA,KITLG,KLHL6,L3MBTL1,LAG3,LCK,LGALS9,LOX,MEF2C,MERTK,MUC3A,NFATC1,PDE5A,PLVAP,PPP2R3C,PTN,RBP4,S100A14,S100A8,SOX9,SYT11,TICAM2,TNRC6B,TREM2,WIPF3 |
| GO_SIGNAL_RELEASE | 5.0e-07 | 2.3e-05 | 736 | 458 | 23 | ABAT,BRSK2,C1QTNF3,CLTRN,GIPC1,GIPR,KCNB1,KCNS3,LIN7B,MEF2C,MYO5A,MYRIP,OPRM1,P2RY4,PPP1R9A,RASL10B,RBP4,SLC30A1,SNPH,STX1B,SYN1,SYT11,TFR2 |
| GO_COGNITION | 6.0e-07 | 3.0e-05 | 736 | 298 | 18 | ATP8A1,C5AR1,FAM107A,FOXO6,FYN,GRIN2A,ITGA8,MAP1A,MAPT,MEF2C,NDRG4,PICALM,PTN,SCN2A,SLC17A7,SYT11,TAFA2,VLDLR |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 6.0e-07 | 3.0e-05 | 736 | 1364 | 45 | ACKR2,ADGRA2,ADGRV1,ADRA1B,APLP1,ARHGEF18,C5AR1,CCL16,CGB7,DAGLB,FLNA,FZD2,GABBR2,GABRR2,GIPC1,GIPR,GNG2,GNG7,GPR132,GRK5,HCAR1,HCAR3,LGR6,OPRM1,OR10G4,OR10Z1,OR2AT4,OR2M3,OR2T33,OR4K17,OR52I1,P2RY2,P2RY4,PALM,PDE6B,PLCL1,PREX1,PRLHR,PTGIR,PTH2R,RASGRP4,RHOB,TAS1R3,TBXA2R,VN1R1 |
| GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 7.0e-07 | 3.3e-05 | 736 | 433 | 22 | ACP5,ACTB,ADGRV1,CIB2,CLDN18,CTSK,DMD,H4C15,LIPA,LOX,MAP1A,NAPSA,NXNL2,P2RY4,PKIB,PLG,PROM1,RBP4,SLC17A7,SOX9,TFF2,WHRN |
| GO_REGULATION_OF_METAL_ION_TRANSPORT | 7.0e-07 | 3.5e-05 | 736 | 400 | 21 | ATG5,ATP1A1,ATP2A1,DMD,EHD3,FHL1,FLNA,FYN,G6PD,GJC2,KCNE2,MYO5A,RYR2,SLC30A1,SLC9A1,SNTA1,STOM,TREM2,TRPC3,TRPC6,WFS1 |
| GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 7.0e-07 | 3.5e-05 | 736 | 334 | 19 | ATG5,ATP2A1,DMD,EHD3,FYN,G6PD,GJC2,GPM6A,GRIN2A,KCNE2,LCK,MCOLN2,MYO5A,OPRM1,PLCL1,RYR2,SLC9A1,TRPC3,TRPC6 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 8.0e-07 | 3.7e-05 | 736 | 1559 | 49 | ABAT,ACP5,AKT3,ANKRD1,BMP7,BPIFB1,BRSK2,C1QTNF3,CBX8,CD96,CRYAB,CTSK,DNASE1L3,ENPP4,EPHA4,EPPK1,F11R,FABP4,FYN,GGT7,GRIK2,HPX,IL2RA,KREMEN1,LAG3,LGALS9,MAP3K9,MAP4K5,MAPT,MEF2C,MUC3A,NME5,OPRM1,PLG,PRKG1,PTN,RAP2A,S100A14,S100A8,SIGLEC10,SYT11,TBXA2R,TICAM2,TMEM259,TREM2,TRPC3,VASH1,WFS1,WNT7B |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 8.0e-07 | 3.8e-05 | 736 | 737 | 30 | ANKRD1,APH1B,ARHGEF18,BMF,BMP7,CIDEB,CLIP3,DAPK3,FOXO3,FYN,GRIK2,GRIN2A,GSN,LCK,LGALS9,LTK,MAP3K9,MAPT,MEF2C,PICALM,PPARGC1A,PREX1,PTN,RHOB,RYBP,S100A8,SLC9A1,UNC5C,USP27X,YWHAQ |
| GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING | 8.0e-07 | 4.0e-05 | 736 | 622 | 27 | ABAT,ADGRA2,CD24,DAAM1,DAPK3,FZD2,GNG2,GRIK2,GRIN2A,GRK5,KREMEN1,LGR6,LIMD1,LRP4,MEF2C,NFATC1,OPRM1,PDE6B,PPP1R9A,SLC17A7,SOX9,STX1B,TMEM170B,TNRC6B,WNT10A,WNT7B,WNT9A |
| GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 8.0e-07 | 4.0e-05 | 736 | 547 | 25 | ACSL3,ATG5,BRSK2,BSN,C4BPB,CLIP3,CLTRN,FES,GIPC1,GRASP,KCNB1,LGALS9,MERTK,NDRG4,P2RY4,PICALM,PROM2,RALB,SLC17A7,STON2,STX1B,SYN1,SYT11,TFR2,TREM2 |
| GO_CONNECTIVE_TISSUE_DEVELOPMENT | 8.0e-07 | 4.0e-05 | 736 | 274 | 17 | BMP7,BMP8B,COL5A1,CTSK,ID2,LOX,LUM,MATN2,MATN4,MEF2C,NKX3-2,OSR2,PPARGC1A,SH3PXD2B,SOX9,WNT7B,WNT9A |
| GO_RESPONSE_TO_CYTOKINE | 1.0e-06 | 4.6e-05 | 736 | 1210 | 41 | ACKR2,ACP5,ADAM9,ANKRD1,CCL16,CD24,CLDN18,CLIP3,DAPK3,EDARADD,FABP4,FOXO3,FYN,GIPC1,GSN,HPX,IFI6,IL10RB,IL21R,IL2RA,IL31RA,IRF6,KRT8,LGALS9,LOX,MAP3K14,MX2,NPR2,OPRM1,PLVAP,POU2F1,PPARGC1A,PTPN20,RHOU,SLC27A1,SOX9,SYNGR1,TFF2,TICAM2,TREM2,TRIM62 |
| GO_EAR_DEVELOPMENT | 1.1e-06 | 5.2e-05 | 736 | 220 | 15 | ADGRV1,ATG5,EPHA4,FZD2,GJB6,INSIG2,ITGA8,KCNK3,LRIG1,NKX3-2,OSR2,PROX1,SOX9,STRC,WHRN |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 1.1e-06 | 5.1e-05 | 736 | 1673 | 51 | ACP5,ANKRD1,ARID5A,ATP1A1,BMP7,C1QTNF3,CBX8,CITED2,CREG1,CRY2,CRYAB,DAPK3,FABP4,FLNA,FOXO3,FOXO6,FYN,H4C15,HSF4,ID2,IGF2,INSIG2,ITM2B,KLF8,L3MBTL1,LAG3,LHX9,LIMD1,MAEL,MEF2A,MEF2C,MLXIPL,NKX3-2,OSR2,POU2F1,PROX1,RCOR2,RIPPLY3,RYBP,SALL4,SLC27A1,SOX9,SREBF2,THRB,TNRC6B,TOB1,USP9X,WFS1,YWHAQ,ZFP90,ZNF608 |
| GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 1.1e-06 | 5.2e-05 | 736 | 378 | 20 | ANKRD1,BMP7,EPHA4,FES,FOXO6,FYN,ITPKA,LTK,MAPT,MEF2C,NAP1L2,NDRG4,P3H1,PPP1R9A,PROX1,PTN,TRAK1,TRPC6,TUBB2B,VLDLR |
| GO_REGULATION_OF_PHOSPHORYLATION | 1.1e-06 | 5.0e-05 | 736 | 1625 | 50 | ACTB,ACVR1B,ADAM9,ADRA1B,ARHGAP8,BMP7,BMP8B,C5AR1,CCL16,CCNI2,CD24,CLIP3,DMD,EPHA4,FABP4,FYN,GJC2,GRIK2,HPX,IGF2,IL31RA,KITLG,LGALS9,LOX,LRP4,MAP3K14,MAP3K9,MAP4K5,MAPT,MLXIPL,NDRG4,OPRM1,OR2AT4,PDE5A,PKIB,PLCL1,PPARGC1A,PPP1R9A,PPP2R3C,PROM2,PROX1,RALB,RAP2A,RNF149,SLC27A1,SOX9,TREM2,TRPC6,VLDLR,WNT7B |
| GO_RESPONSE_TO_NUTRIENT | 1.1e-06 | 5.2e-05 | 736 | 220 | 15 | ABCG8,ACSL3,AQP3,BMP7,CIB2,FES,FYN,GIPR,GSN,MT-CYB,P2RY2,P2RY4,PTN,TBXA2R,TRPC3 |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 1.2e-06 | 5.4e-05 | 736 | 1175 | 40 | ADGRA2,AKT3,AMOT,ANKRD1,AQP1,ATG5,BMP7,C5AR1,CCDC103,CITED2,COL5A1,FBN1,FZD2,G6PD,GAB1,ID2,IRX4,LOX,LTBP1,MEF2A,MEF2C,MYOM2,NDRG4,NFATC1,PAM,PLG,PROX1,PTN,RBP4,RHOB,RIPPLY3,RYR2,SALL4,SH3PXD2B,SLC9A1,SOX9,TBXA2R,TMEM65,VASH1,WNT7B |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 1.4e-06 | 6.3e-05 | 736 | 1782 | 53 | ACSL3,BMF,C1QTNF3,CCDC103,CCDC114,CCDC65,CD79A,CLIP3,CLTRN,CRYAB,DMD,DNAJC28,EHD3,FAM107A,FES,GSN,H4C15,HSF4,KCNB1,KCND3,KCNS3,LGI1,LMOD3,LRP4,MAPT,MT-CO3,MT-ND1,MT-ND3,MT-ND4,MYOM2,NAP1L2,NSG2,PAM,PARD6B,PFN4,PICALM,PIH1D3,PPARGC1A,PPP1R9A,PREX1,QPRT,RALB,SCARA5,SEC16B,SETSIP,SH3PXD2B,SLC9A1,SOX9,SPTBN5,STOM,STX1B,WDR63,XPA |
| GO_REPRODUCTION | 1.5e-06 | 6.6e-05 | 736 | 1457 | 46 | ABAT,ACVR1B,ADAM19,ANKRD31,BMP7,BNC1,BSG,CDKL2,CGB7,CITED2,FLNA,IGF2,KITLG,KRT8,LGALS9,LHX9,MAEL,MERTK,NME5,NPR2,OPRM1,OVGP1,PAM,PCDHGA4,PDE5A,PIH1D3,PLG,PRLHR,PTN,RBP4,RIMBP3,RSPH1,SH3PXD2B,SOX9,SYCP2,SYCP3,TERB1,THRB,TRPC3,TRPC6,TXNDC2,USP9X,VASH1,WIPF3,WNT7B,ZSCAN2 |
| GO_MEMORY | 1.6e-06 | 7.2e-05 | 736 | 119 | 11 | FOXO6,GRIN2A,ITGA8,MAP1A,MAPT,PTN,SCN2A,SLC17A7,SYT11,TAFA2,VLDLR |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 1.6e-06 | 7.1e-05 | 736 | 723 | 29 | ABAT,ACAA2,ACOT4,ACSL3,ACSS1,AGXT,C1QTNF3,CARNS1,EPHX2,G6PD,GADL1,GGT7,INSIG2,ITPKA,MGST3,MLXIPL,MOXD1,MYO5A,NME5,NME9,PDE5A,PLCL1,PPARGC1A,PROX1,RBP4,SCD5,SREBF2,THNSL2,UGP2 |
| GO_DENDRITE_MORPHOGENESIS | 1.7e-06 | 7.4e-05 | 736 | 144 | 12 | EPHA4,FYN,ITPKA,LRP4,MEF2A,PICALM,PPP1R9A,PTN,RAP2A,TRAK1,TRPC6,VLDLR |
| GO_EAR_MORPHOGENESIS | 1.8e-06 | 7.8e-05 | 736 | 120 | 11 | FZD2,GJB6,INSIG2,ITGA8,LRIG1,NKX3-2,OSR2,PROX1,SOX9,STRC,WHRN |
| GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 1.8e-06 | 7.9e-05 | 736 | 390 | 20 | ANKRD1,BMP7,EPHA4,FES,FNBP1L,FOXO6,FYN,GPM6A,ITPKA,LTK,MAPT,NDRG4,P3H1,PALM,PPP1R9A,PROM2,PTN,TRAK1,TUBB2B,VLDLR |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 1.8e-06 | 7.9e-05 | 736 | 534 | 24 | CLIP3,DAPK3,F11R,FAM107A,FES,FLNA,GSN,LMOD3,MAP1A,MAP9,MAPT,MEF2C,PAM,PFN4,PPP1R9A,PREX1,PROX1,RHOB,RHOU,S100A8,SH3PXD2B,SLC9A1,SPTBN5,SYNPO2 |
| GO_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION | 1.8e-06 | 7.8e-05 | 736 | 97 | 10 | ADRA1B,ATP1A1,ATP2A1,DMD,EHD3,FLNA,PDE5A,RYR2,SLC9A1,TNNI3K |
| GO_REGULATION_OF_TRANSPORTER_ACTIVITY | 1.8e-06 | 7.9e-05 | 736 | 290 | 17 | ACTB,ATP2A1,DMD,EHD3,FHL1,GRIA2,GRIN2A,KCNE2,MEF2C,MYO5A,OPRM1,PPARGC1A,RYR2,SLC9A1,STOM,TREM2,TRPC6 |
| GO_RESPONSE_TO_OXYGEN_LEVELS | 1.9e-06 | 8.1e-05 | 736 | 391 | 20 | ABAT,ACAA2,ANKRD1,AQP1,AQP3,BMP7,CD24,CITED2,CRYAB,KCNK3,LIMD1,MT-CYB,MT-ND4,PAM,PPARGC1A,PTN,RYR2,SCN2A,SLC9A1,TRPC6 |
| GO_WOUND_HEALING | 1.9e-06 | 7.9e-05 | 736 | 572 | 25 | ABAT,ACTB,C4BPB,COL5A1,EHD3,ENPP4,EPPK1,F11R,FLNA,FYN,GNG2,GSN,LCK,LGR6,LOX,MERTK,OPRM1,PLG,PRKG1,PTN,S100A8,SYT11,TBXA2R,TRPC3,TRPC6 |
| GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 2.0e-06 | 8.3e-05 | 736 | 499 | 23 | ATG5,ATP2A1,DMD,EHD3,FYN,G6PD,GJC2,GPM6A,GRIN2A,KCNE2,LCK,MCOLN2,MYO5A,OPRM1,PLCL1,RYR2,SLC30A1,SLC39A11,SLC9A1,TMEM163,TRPC3,TRPC6,WFS1 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 2.0e-06 | 8.4e-05 | 736 | 537 | 24 | ACSL3,ACTB,ASTN2,BRSK2,CLDN18,CLIP3,FLNA,FYN,GRASP,GSN,KCNB1,LRP4,MAP1A,MAPT,PICALM,PTN,RALB,RHOU,SEC16B,SREBF2,STOM,SYT11,TREM2,YWHAQ |
| GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | 2.0e-06 | 8.4e-05 | 736 | 358 | 19 | ACP5,ADAM9,ANKRD1,ATP4B,C5AR1,CD24,CD96,GJB6,LGALS9,MEF2C,OPRM1,PPARGC1A,PTGIR,S100A14,S100A8,SLPI,TBXA2R,TICAM2,TREM2 |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 2.1e-06 | 8.5e-05 | 736 | 614 | 26 | ACTB,ANKRD1,APLP1,AQP1,ATP1A1,BMP7,CIB2,CRY2,FAM107A,FES,FLNA,GNG2,MEF2C,MT-ND3,NSG2,OPRM1,P2RY2,P2RY4,PALM,PGRMC2,PPARGC1A,PTN,RALB,RYR2,SLC9A1,THRB |
| GO_EXOCYTOSIS | 2.2e-06 | 8.9e-05 | 736 | 900 | 33 | ATP8A1,BRSK2,C5AR1,CLTRN,CREG1,ENPP4,FAF2,FES,FLNA,FUCA1,GIPC1,GSN,IGF2,KCNB1,LGALS9,LIN7B,MYO5A,OSTF1,P2RY4,PLG,QPCT,RALB,S100A8,SLPI,SNPH,STBD1,STOM,STX1B,SYN1,SYNGR1,SYT11,SYTL3,TICAM2 |
| GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | 2.3e-06 | 9.5e-05 | 736 | 328 | 18 | ADSS1,ANKRD1,AQP1,ATP1A1,BMF,CRY2,CRYAB,F11R,MAP3K14,PALM,PDE6B,PIEZO2,PTN,RHOB,SCN2A,SLC9A1,SOX9,XPA |
| GO_OSSIFICATION | 2.3e-06 | 9.5e-05 | 736 | 396 | 20 | ACP5,ADGRV1,BMP7,BMP8B,CTSK,ID2,IGF2,KREMEN1,LIMD1,LOX,LRP4,MEF2C,NPR2,OSR2,OSTF1,PTN,SH3PXD2B,SOX9,TOB1,WNT7B |
| GO_CELL_CYCLE | 2.4e-06 | 9.7e-05 | 736 | 1864 | 54 | ACTB,ACVR1B,ANKRD31,BMP7,BRSK2,BTC,BTG4,CCDC8,CCNI2,CDK18,CDKL2,CITED2,DAPK3,FAM107A,FBXL18,FES,FHL1,FLNA,GIPC1,GJC2,GMNC,GOLGA8R,GPR132,GRK5,HMCN1,ID2,IGF2,IRF6,KCNH5,L3MBTL1,MAEL,MAP9,MLXIPL,MX2,NPR2,PARD6B,PROX1,RALB,RHOB,RHOU,RSPH1,RYBP,SEPTIN14,SNX18,SOX9,STK33,SYCP2,SYCP3,TERB1,TUBA1A,TUBB2B,USP9X,VASH1,WNT9A |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 2.4e-06 | 9.5e-05 | 736 | 1164 | 39 | ABAT,ACAA2,ACOT4,ACSL3,ACSS1,ADSS1,AGXT,ALDH1L2,AMDHD1,BSG,CARNS1,CHPF2,CHST1,CYP3A5,DAGLB,ECH1,EPHX2,GADL1,GGT7,HGD,INSIG2,LUM,MDH1B,MGST3,MLXIPL,MYO5A,PAM,PIPOX,PPARGC1A,PROX1,QPRT,SCD5,SLC23A2,SLC27A1,SLC9A1,SULT1A2,THNSL2,TPST2,UGP2 |
| GO_REGULATION_OF_BODY_FLUID_LEVELS | 2.5e-06 | 9.9e-05 | 736 | 506 | 23 | ABAT,ACTB,AQP1,AQP3,ATG5,BTC,C4BPB,EHD3,ENPP4,F11R,FLNA,FYN,GNG2,LCK,MERTK,P2RY2,PAM,PLG,PRKG1,TBXA2R,TRPC3,TRPC6,WFS1 |
| GO_ENDOCYTOSIS | 2.6e-06 | 1.0e-04 | 736 | 661 | 27 | ACKR2,ACTB,AMPH,APLP1,CLIP3,EHBP1,ELMO1,FNBP1L,GSN,HHIPL1,HPX,IGLV1-51,LRP4,MX2,PICALM,PROM2,RHOU,SCARA5,SLC17A7,SNX18,STON2,STX1B,SYT11,TFR2,TREM2,VLDLR,WIPF3 |
| GO_RESPONSE_TO_HORMONE | 2.6e-06 | 1.0e-04 | 736 | 994 | 35 | ADAM9,AGXT,AQP1,ATP1A1,BMP7,BSG,CGB7,CRY2,CRYAB,FAM107A,FBN1,FOXO3,FOXO6,FYN,GAB1,GNG2,IGF2,INSIG2,LOX,MEF2C,MMP15,MT-CYB,MT-ND3,MYO5A,OPRM1,P2RY4,PAM,PGRMC2,PPARGC1A,PTN,SLC27A1,SLC9A1,TBXA2R,THRB,WNT7B |
| GO_TRANSITION_METAL_ION_TRANSPORT | 2.7e-06 | 1.0e-04 | 736 | 125 | 11 | FLVCR2,HEPH,HPX,MELTF,SCARA5,SLC30A1,SLC39A11,TFR2,TMEM163,TRPC3,TRPC6 |
| GO_ASTROCYTE_DIFFERENTIATION | 2.8e-06 | 1.1e-04 | 736 | 80 | 9 | C5AR1,EPHA4,ID2,LAMC3,MAPT,POU3F2,S100A8,SOX9,TREM2 |
| GO_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 2.9e-06 | 1.1e-04 | 736 | 268 | 16 | ACSL3,ACTB,BSG,CLIP3,EHD3,F11R,FLNA,GRASP,KCNB1,MYO5A,PALM,PICALM,RAB40A,RAP2A,RILPL2,TREM2 |
| GO_PEROXISOME_ORGANIZATION | 3.1e-06 | 1.2e-04 | 736 | 81 | 9 | ACOT4,AGXT,ECH1,EPHX2,PEX16,PIPOX,SEC16B,TMEM135,USP9X |
| GO_MEMBRANE_ORGANIZATION | 3.3e-06 | 1.3e-04 | 736 | 875 | 32 | A4GALT,ACAA2,ACTB,AMPH,ATP10B,ATP8A1,BMF,BTC,CD24,CLTRN,COL5A1,ELMO1,FNBP1L,GSN,LRP4,MX2,PICALM,PLEKHA8,PTN,RILPL2,SEC16B,SEC31B,SLC9A1,SNX18,STON2,STX1B,SUN3,SYNGR1,SYT11,TREM2,VPS8,YWHAQ |
| GO_ORGANELLE_ASSEMBLY | 3.4e-06 | 1.3e-04 | 736 | 835 | 31 | ANKRD1,ATG5,BBS9,CCDC103,CCDC114,CCDC65,DNAJB13,EHD3,FLNA,FNBP1L,GMNC,GOLGA8R,GSN,KIAA1324,KRT8,LIMD1,LMOD3,MAP9,MAPT,MEF2A,MEF2C,MYOM2,NME5,PIH1D3,PROX1,RALB,RSPH1,SH3PXD2B,SYNPO2,TUBA1A,WDR63 |
| GO_OXIDATION_REDUCTION_PROCESS | 3.4e-06 | 1.3e-04 | 736 | 1005 | 35 | ACAA2,ACSS1,ALDH1L2,CARNS1,COX8C,CYP3A5,ECH1,FRRS1,G6PD,HEPH,HGD,HSD17B13,IGF2,LOX,MDH1B,MGST3,MOXD1,MSRB3,MT-CO1,MT-CO3,MT-CYB,MT-ND1,MT-ND3,MT-ND4,MT-ND4L,NDUFA4,P3H1,P4HA1,P4HA2,PAM,PIPOX,PPARGC1A,SCD5,STBD1,UGP2 |
| GO_RESPONSE_TO_ALCOHOL | 3.4e-06 | 1.3e-04 | 736 | 240 | 15 | ABAT,CLDN18,FYN,G6PD,GNG2,GRIN2A,GSN,MT-CYB,MT-ND4,OPRM1,P2RY4,RBP4,S100A8,TBXA2R,UNC79 |
| GO_RESPONSE_TO_BACTERIUM | 3.4e-06 | 1.3e-04 | 736 | 711 | 28 | ACP5,ADAM9,ANKRD1,ATP4B,C4BPB,C5AR1,CD24,CD96,FABP4,GJB6,GPM6A,HMCN1,IKZF3,KLHL6,LGALS9,MACROD2,MEF2C,OPRM1,PPARGC1A,PTGIR,S100A14,S100A8,SLPI,SYT11,TBXA2R,TENT5A,TICAM2,TREM2 |
| GO_MAINTENANCE_OF_LOCATION | 3.6e-06 | 1.3e-04 | 736 | 338 | 18 | ATG5,ATP2A1,DMD,FBN1,FLNA,GSN,LCK,LTBP1,MCOLN2,MYO5A,PFN4,PLCL1,RYR2,S100A8,SLC17A7,SREBF2,SUN3,TLN2 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 3.9e-06 | 1.5e-04 | 736 | 1280 | 41 | ANKRD1,ARID5A,BMP7,CBX8,CITED2,CREG1,CRY2,CRYAB,FABP4,FLNA,FOXO3,FOXO6,H4C15,HSF4,ID2,IGF2,KLF8,L3MBTL1,LHX9,LIMD1,MAEL,MEF2A,MEF2C,MLXIPL,NKX3-2,OSR2,POU2F1,PROX1,RCOR2,RIPPLY3,RYBP,SALL4,SOX9,SREBF2,THRB,TOB1,USP9X,WFS1,YWHAQ,ZFP90,ZNF608 |
| GO_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | 4.2e-06 | 1.6e-04 | 736 | 214 | 14 | ACTB,AMPH,BRSK2,BSN,GIPC1,MX2,P2RY4,PICALM,SLC17A7,SNPH,STON2,STX1B,SYN1,SYT11 |
| GO_POTASSIUM_ION_TRANSPORT | 4.3e-06 | 1.6e-04 | 736 | 245 | 15 | AQP1,ATP1A1,ATP4B,FHL1,FLNA,KCNB1,KCND3,KCNE2,KCNH5,KCNK13,KCNK3,KCNS3,SLC12A7,SLC9A1,TREM2 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 4.4e-06 | 1.6e-04 | 736 | 1151 | 38 | ACOT4,AGXT,ARL4C,ARL5B,BRSK2,CD24,ECH1,EPHX2,FAF2,FLNA,FYN,GIPC1,GRASP,KCNB1,LCA5L,MAP1A,MYRIP,PEX16,PIPOX,RAB30,RAB36,RAB40A,RAB6B,RHOB,RHOU,RILPL2,SEC16B,SEC31B,SREBF2,STOM,STX1B,SYNGR1,SYTL3,TBC1D8B,TICAM2,TRAK1,USP9X,YWHAQ |
| GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | 4.4e-06 | 1.6e-04 | 736 | 277 | 16 | ABAT,ATP2A1,ATP8A1,DMD,EHD3,FHL1,FLNA,G6PD,GJC2,KCNE2,RYR2,SLC9A1,TREM2,TRPC3,TRPC6,WFS1 |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 4.4e-06 | 1.6e-04 | 736 | 1287 | 41 | AMOT,AQP1,ARHGAP29,ARHGAP42,ARHGAP8,ATP4B,BRSK2,C5AR1,CCDC8,CCL16,CIDEB,CRY2,CRYAB,EPHA4,F11R,FYN,GRIN2A,GSN,IFI6,LCK,LGALS9,LMF1,MAPT,MEF2C,MYO9A,PERP,PICALM,PREX1,PRKG1,PROM2,PTN,RASGRP4,RCAN2,S100A8,SLPI,SNX18,TBC1D8B,VPS9D1,WFDC3,WFIKKN1,WNT9A |
| GO_REGULATION_OF_SYNAPTIC_PLASTICITY | 4.7e-06 | 1.7e-04 | 736 | 187 | 13 | EPHA4,FAM107A,GIPC1,GRIK2,GRIN2A,ITPKA,KCNB1,MAP1A,MAPT,MEF2C,PPP1R9A,PTN,SYNGR1 |
| GO_ACTION_POTENTIAL | 4.9e-06 | 1.7e-04 | 736 | 133 | 11 | ATP1A1,DMD,FLNA,GRIK2,KCNB1,KCND3,KCNE2,RYR2,SCN2A,SLC9A1,SNTA1 |
| GO_ODONTOGENESIS | 4.9e-06 | 1.7e-04 | 736 | 133 | 11 | AQP1,AQP3,BMP7,BSG,LRP4,MYO5A,OSR2,PAM,PERP,SSUH2,WNT10A |
| GO_MITOCHONDRION_ORGANIZATION | 5.0e-06 | 1.8e-04 | 736 | 528 | 23 | ACAA2,AKT3,ATG5,ATP2A1,BMF,CIDEB,CTSK,IFI6,MAPT,MEF2A,MT-ND1,MT-ND3,MT-ND4,MX2,PPARGC1A,RHOU,SLC9A1,SPATA18,SREBF2,TMEM135,TRAK1,TREM2,YWHAQ |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 5.0e-06 | 1.8e-04 | 736 | 188 | 13 | ACSL3,ACTB,CLIP3,FYN,GRASP,GSN,KCNB1,LRP4,PICALM,PTN,STOM,TREM2,YWHAQ |
| GO_CELL_SUBSTRATE_ADHESION | 5.3e-06 | 1.9e-04 | 736 | 348 | 18 | ADAM9,CD96,DAPK3,FAM107A,FLNA,ITGA8,ITGB6,LAMC3,LYPD3,MELTF,MERTK,NID2,PLG,PREX1,PTN,SLC9A1,STRC,TECTA |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 5.4e-06 | 1.9e-04 | 736 | 569 | 24 | AMOT,ARHGAP29,ARHGAP42,ARHGAP8,ARHGEF18,ARHGEF33,CAVIN4,CGNL1,ELMO1,F11R,KITLG,MYO9A,PREX1,RAB30,RAB36,RAB40A,RAB6B,RALB,RAP2A,RASGRP4,RHOB,RHOU,TNK1,YWHAQ |
| GO_BONE_DEVELOPMENT | 5.5e-06 | 1.9e-04 | 736 | 219 | 14 | ACP5,CLDN18,FBN1,INSIG2,LOX,MATN2,MATN4,MEF2C,NPR2,OSR2,P3H1,SH3PXD2B,SOX9,TTC9 |
| GO_NEURON_PROJECTION_GUIDANCE | 5.5e-06 | 1.9e-04 | 736 | 282 | 16 | ARTN,BMP7,BSG,EFNA4,EPHA4,FYN,GAB1,LGI1,LGR6,LHX9,MATN2,MYOT,SPTBN5,TUBB2B,UNC5C,VLDLR |
| GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 6.0e-06 | 2.1e-04 | 736 | 351 | 18 | CLIP3,CRYAB,DAPK3,FES,FLNA,GSN,LMOD3,MAP1A,MAPT,MEF2C,PFN4,PPP1R9A,PREX1,PROX1,SH3PXD2B,SLC9A1,SPTBN5,SYNPO2 |
| GO_GROWTH | 6.2e-06 | 2.1e-04 | 736 | 990 | 34 | ACVR1B,CREG1,CRYAB,EPPK1,FAM107A,FHL1,G6PD,GSN,IGF2,LGI1,LGR6,LRP4,MAEL,MAPT,MATN2,MATN4,MEF2C,NDRG4,PLG,POU3F2,PROX1,PTN,RBP4,S100A8,SALL4,SH3PXD2B,SLC9A1,SOX9,TNK1,UNC79,USP9X,WFS1,WNT7B,XPA |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 6.2e-06 | 2.1e-04 | 736 | 990 | 34 | ACVR1B,ARTN,ATG5,CD101,CD79A,CITED2,CLDN18,EFNA4,FBN1,FES,FOXO3,G6PD,H4C15,ID2,IKZF3,IL2RA,IL31RA,KITLG,L3MBTL1,LAG3,LCK,LGALS9,LOX,MEF2C,MERTK,NKX3-2,PICALM,PPP2R3C,PREX1,PTN,RASGRP4,STON2,TNRC6B,TREM2 |
| GO_TISSUE_HOMEOSTASIS | 7.1e-06 | 2.4e-04 | 736 | 224 | 14 | ACP5,ACTB,ADGRV1,CIB2,CLDN18,CTSK,LIPA,NAPSA,NXNL2,PROM1,RBP4,SOX9,TFF2,WHRN |
| GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 7.5e-06 | 2.6e-04 | 736 | 289 | 16 | ANKRD1,BMP7,EPHA4,FES,FOXO6,FYN,ITPKA,LTK,MAPT,NDRG4,P3H1,PPP1R9A,PTN,TRAK1,TUBB2B,VLDLR |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 7.6e-06 | 2.6e-04 | 736 | 1410 | 43 | ADAM9,ASB11,BRSK2,C4BPB,CTIF,CTSK,DNASE1L3,EPHA4,FAF2,FBXL18,FBXO27,FLNA,FUCA1,FYN,GIPC1,GRIN2A,KCNE2,LUM,MAP1A,NAPSA,OVGP1,PLG,RHBDD2,RNF149,RYBP,SLC9A1,SOX9,SPATA18,STBD1,STK31,SYNPO2,TMEM259,TNRC6B,TOB1,TREM2,TTC3,TTC37,UBQLNL,UGGT1,USP27X,USP9X,VLDLR,WFS1 |
| GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | 7.8e-06 | 2.6e-04 | 736 | 167 | 12 | ADGRV1,CNTN5,FYN,GJB6,LRIG1,OTOGL,PIEZO2,STRC,TECTA,THRB,WFS1,WHRN |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 8.8e-06 | 3.0e-04 | 736 | 547 | 23 | ABAT,ACAA2,ACSS1,CARNS1,CYP3A5,EPHX2,G6PD,GIPC1,GRIN2A,INSIG2,ITPKA,LIPA,LMF1,MOGAT3,MOXD1,MYO5A,PLCL1,PMEL,PROX1,RBP4,SREBF2,SULT1A2,VLDLR |
| GO_CELL_JUNCTION_ORGANIZATION | 8.9e-06 | 3.0e-04 | 736 | 293 | 16 | ACTB,ARVCF,CLDN6,DAPK3,F11R,FAM107A,FLNA,GJB6,MYO9A,NECTIN4,PARD6B,PERP,SLC9A1,TLN2,TNS1,WHRN |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 9.1e-06 | 3.0e-04 | 736 | 627 | 25 | ACOT4,ACSL3,ACSS1,ADSS1,AK8,APOBEC3H,ENPP4,MACROD2,MLXIPL,NME5,NME9,NMNAT2,NMRK1,NPR2,PDE5A,PIPOX,PPARGC1A,QPRT,SCD5,SULT1A2,TPST2,TREM2,UGGT1,UGP2,VPS9D1 |
| GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | 9.2e-06 | 3.1e-04 | 736 | 261 | 15 | ATG5,ATP2A1,DMD,EHD3,FYN,G6PD,GJC2,KCNE2,MYO5A,RYR2,SLC30A1,SLC9A1,TRPC3,TRPC6,WFS1 |
| GO_RENAL_SYSTEM_DEVELOPMENT | 9.3e-06 | 3.1e-04 | 736 | 294 | 16 | BMP7,CD24,COL4A4,EPHA4,FBN1,ID2,ITGA8,LRP4,MEF2C,OSR2,PROM1,PROX1,RBP4,SOX9,WFS1,WNT7B |
| GO_TISSUE_MORPHOGENESIS | 9.7e-06 | 3.2e-04 | 736 | 670 | 26 | ANKRD1,ARTN,ASTN2,BMP7,BRSK2,CCDC103,COL5A1,CRYGS,DAAM1,EPHA4,FLNA,FZD2,ITGA8,MATN2,MATN4,MEF2C,MYO9A,MYOM2,NDRG4,PROX1,RHOB,RYR2,SALL4,SOX9,WNT10A,WNT7B |
| GO_DEFENSE_RESPONSE | 1.0e-05 | 3.4e-04 | 736 | 1765 | 50 | ACKR2,ACP5,APOBEC3H,ARID5A,BPIFB1,C1QTNF3,C4BPB,C5AR1,CCL16,CD96,CHST1,CTSK,DAPK3,DNASE1L3,EPHX2,F11R,FABP4,FLNA,FYN,GRIK2,GSN,HPX,IFI6,IL10RB,IL2RA,IL31RA,IRF6,ITGB6,LAG3,LGALS9,LIPA,MAP3K14,MAPT,MCOLN2,MEF2C,MUC3A,MX2,OPRM1,PTGIR,PTN,S100A14,S100A8,SIGLEC10,SLPI,SYT11,TBXA2R,TFR2,TICAM2,TREM2,TRIM62 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 1.0e-05 | 3.4e-04 | 736 | 1716 | 49 | AKT3,AQP1,BMP7,BNC1,BTC,BTG4,C5AR1,CBX8,CD24,CNN1,EPPK1,FES,FLNA,FYN,GJB6,GJC2,GRK5,HSF4,ID2,IGF2,IKZF3,IL2RA,IL31RA,IRF6,KITLG,LCK,LGALS9,LTK,MEF2C,MLXIPL,NDRG4,OPRM1,OSR2,P3H1,PDE5A,PLG,POU3F2,PPARGC1A,PRKG1,PROX1,PTGIR,PTN,RBP4,RIPPLY3,SOX9,TNK1,TOB1,VASH1,WNT9A |
| GO_SYNAPTIC_VESICLE_RECYCLING | 1.1e-05 | 3.6e-04 | 736 | 72 | 8 | ACTB,AMPH,MX2,PICALM,SLC17A7,STON2,STX1B,SYT11 |
| GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 1.2e-05 | 3.9e-04 | 736 | 204 | 13 | ATP2A1,CLIP3,DMD,EHD3,FLNA,G6PD,GJC2,KCNE2,MEF2A,RYR2,SLC9A1,TREM2,TRPC6 |
| GO_REGULATION_OF_CARDIAC_CONDUCTION | 1.2e-05 | 4.0e-04 | 736 | 73 | 8 | ATP1A1,ATP2A1,EHD3,FLNA,NPR2,RYR2,TMEM65,TNNI3K |
| GO_ACTIN_MEDIATED_CELL_CONTRACTION | 1.3e-05 | 4.2e-04 | 736 | 121 | 10 | ATP1A1,ATP2A1,DES,DMD,FLNA,KCND3,KCNE2,RYR2,SLC9A1,SNTA1 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 1.3e-05 | 4.2e-04 | 736 | 1117 | 36 | A4GALT,ACOT4,ACSL3,ACSS1,ADSS1,APOBEC3H,CHPF2,CHST1,ENPP4,FBXO27,FUCA1,G6PD,GBGT1,HS2ST1,ITM2B,LMF1,LUM,MACROD2,MLXIPL,MUC3A,NME5,NME9,NPR2,OVGP1,PDE5A,PIPOX,PPARGC1A,SCD5,SLC9A1,SULT1A2,TPST2,TRAK1,TREM2,UGGT1,UGP2,VPS9D1 |
| GO_DRUG_METABOLIC_PROCESS | 1.3e-05 | 4.2e-04 | 736 | 600 | 24 | ABAT,ACP5,ACSS1,ADSS1,AGXT,ALDH1L2,AMDHD1,CARNS1,CYP3A5,EPHX2,FYN,GGT7,GRIN2A,HGD,MOXD1,NOXA1,OVGP1,PIPOX,PPARGC1A,QPRT,SULT1A2,TREM2,VPS9D1,XPNPEP1 |
| GO_INFLAMMATORY_RESPONSE | 1.3e-05 | 4.2e-04 | 736 | 765 | 28 | ACKR2,ACP5,C1QTNF3,C5AR1,CCL16,CD96,CHST1,DNASE1L3,EPHX2,F11R,FABP4,IL10RB,IL2RA,IL31RA,ITGB6,LGALS9,LIPA,MAPT,OPRM1,PTGIR,PTN,S100A8,SIGLEC10,SYT11,TBXA2R,TFR2,TICAM2,TREM2 |
| GO_PEPTIDE_SECRETION | 1.3e-05 | 4.2e-04 | 736 | 641 | 25 | ABAT,ADAM9,ANKRD1,ATG5,BRSK2,C1QTNF3,CLTRN,GIPR,ITGB6,KCNB1,KCNS3,LGALS9,LMF1,MCOLN2,MYO5A,MYRIP,OPRM1,P3H1,PAM,RASL10B,RBP4,S100A8,SYT11,TFR2,TREM2 |
| GO_PROTEIN_CATABOLIC_PROCESS | 1.3e-05 | 4.2e-04 | 736 | 938 | 32 | ADAM9,ASB11,BRSK2,C4BPB,CTSK,EPHA4,FAF2,FBXL18,FBXO27,FLNA,FYN,GIPC1,GRIN2A,KCNE2,MAP1A,NAPSA,PLG,RHBDD2,RNF149,RYBP,SOX9,SPATA18,SYNPO2,TMEM259,TREM2,TTC3,UBQLNL,UGGT1,USP27X,USP9X,VLDLR,WFS1 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 1.4e-05 | 4.4e-04 | 736 | 603 | 24 | ACAA2,ACVR1B,ATP2A1,BMF,BRSK2,CD24,CIDEB,DAPK3,FYN,GSN,IFI6,KITLG,KRT8,LCK,LGALS9,MAEL,NME5,PERP,S100A8,SCN2A,TICAM2,WFS1,XPA,YWHAQ |
| GO_CARDIAC_MUSCLE_CELL_CONTRACTION | 1.4e-05 | 4.3e-04 | 736 | 74 | 8 | ATP1A1,ATP2A1,FLNA,KCND3,KCNE2,RYR2,SLC9A1,SNTA1 |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 1.4e-05 | 4.4e-04 | 736 | 604 | 24 | ACVR1B,ADAM9,ADGRA2,AKT3,ARTN,ATP8A1,BMP7,C5AR1,DAPK3,FAM107A,FLNA,GAB1,KITLG,LGALS9,LGR6,PLVAP,PREX1,PROX1,PTN,RHOB,S100A14,SOX9,TREM2,TUBB2B |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 1.4e-05 | 4.4e-04 | 736 | 942 | 32 | ATG5,BMF,BMP7,CLIP3,CLSTN2,CLTRN,CRYAB,DAPK3,FAM107A,FES,FLNA,FNBP1L,GPM6A,GSN,KIAA1324,LMOD3,MAPT,MEF2C,PALM,PFN4,PPP1R9A,PREX1,PROX1,RALB,SH3PXD2B,SLC9A1,SOX9,SPTBN5,STX1B,SYNPO2,SYT11,XPA |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1.4e-05 | 4.3e-04 | 736 | 767 | 28 | ABAT,ACSL3,ADAM9,ANKRD1,ATG5,BRSK2,C1QTNF3,CLTRN,FLNA,FYN,GIPR,GRASP,KCNB1,KCNS3,LGALS9,MAPT,MYRIP,OPRM1,P3H1,PAM,RBP4,RHOU,SEC16B,SREBF2,STOM,SYT11,TREM2,YWHAQ |
| GO_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 1.4e-05 | 4.4e-04 | 736 | 149 | 11 | GPM6A,LAMC3,MERTK,PDE6B,PROM1,PROX1,PTN,RBP4,SLC17A7,SOX9,THRB |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 1.5e-05 | 4.6e-04 | 736 | 1124 | 36 | ABAT,ACP5,ADGRA2,ARTN,BPIFB1,C1QTNF3,C5AR1,CD96,CTSK,DNASE1L3,ENPP4,EPHA4,EPPK1,F11R,FABP4,FYN,HPX,IL2RA,KREMEN1,LAG3,LGALS9,MUC3A,OPRM1,PDE6B,PLG,PPP2R3C,PRKG1,PTN,S100A14,S100A8,SIGLEC10,SYT11,TBXA2R,TICAM2,TREM2,TUBB2B |
| GO_EPITHELIAL_CELL_DIFFERENTIATION | 1.6e-05 | 4.9e-04 | 736 | 774 | 28 | ADAM9,AQP3,BMP7,CD24,CTSK,F11R,FLNA,FZD2,ID2,IL31RA,IRF6,KRT38,KRT8,KRTAP5-11,MEF2C,MYO9A,NKX3-2,PERP,PROM1,PROX1,PTN,RILPL2,SETSIP,SOX9,STRC,THRB,WHRN,WNT7B |
Num: 14 (Pathways: 373 DK: 6)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (6) | CDK20, CLK4, DYRK3, DYRK4, NEK3, NUAK2 |
| Light Kinase (12) | ACVR2B, AURKC, BMPR1B, BRAF, CDK7, CSNK1E, MAP3K20, PIM3, PTK6, RIPK2, TRIB1, TRPM6 |
| Non-kinase Count | 536 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 554 | 1748 | 83 | ADCY10,ADORA2A,ARG2,ARHGEF2,ATF6,BAG6,BBC3,BCL2L13,BIRC2,BMP2,BMPR1B,BRAF,BTG1,CBX4,CDKN1B,CEBPB,CFLAR,CHMP4A,CPEB4,CSF2,CSF3,CXCL10,DDIT4,DEDD,DYRK3,FCMR,FGF2,GADD45B,HCLS1,HMGA2,HRK,HYOU1,ICAM1,IDO1,IFIT2,IKBKG,IL1A,IL1B,IL6,INHBA,ITPRIP,JMY,KCNMA1,KRT18,LTBR,MAP3K20,MYDGF,NCK1,NFKBIA,NGF,NLRC4,NLRP3,NPAS2,NUAK2,NUPR1,PIM3,PLAUR,PLK5,PPARG,PRLR,PTGS2,RBCK1,RIPK2,RNF144B,SIAH1,SLC35F6,SNAI2,SOD2,SP100,STAMBP,STYXL1,SYCE3,TNFAIP3,TNFAIP8,TNFRSF12A,TRAF1,TSC22D3,TSLP,TXNIP,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 554 | 1559 | 73 | ADORA2A,ADTRP,ANXA2P2,ARG2,ARHGEF2,ATF6,BAG6,BIRC2,BMP2,CDKN1B,CEBPB,DDX58,DHX58,DUSP10,DYRK3,ERLEC1,ETS1,FGF2,FICD,GADD45B,HMGA2,HYOU1,IDO1,IFIH1,IFIT1,IKBKG,IL1A,IL1B,IL6,INAVA,IRF1,LRIG2,LTBR,MANF,MAP3K20,MCTP1,METRNL,MUC12,NBR1,NCK1,NFE2L1,NFKBIA,NFKBIZ,NLRC4,NLRP3,NPAS2,NUPR1,PER1,PLAUR,PLEK,PPARG,PTGS2,RELB,RIPK2,RNF13,RNF169,RNF185,RSAD2,SLC7A2,SNAI2,SOCS1,SOD2,TIFA,TNFAIP3,TNFRSF12A,TNIP1,TNIP3,TRIM38,TSLP,UBE2J1,VEGFA,XBP1,ZC3H12A |
| GO_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 1765 | 77 | ADORA2A,ANXA3,ARG2,ARHGEF2,BIRC2,BMP2,BMPR1B,C3AR1,C5AR2,CEBPB,CSF3R,CXCL1,CXCL10,DDIT4,DDX58,DHX58,DUSP10,ELF3,ELF4,ETS1,FCMR,GBP4,HDAC9,ICAM1,IDO1,IFIH1,IFIT1,IFIT2,IKBKG,IL1A,IL1B,IL32,IL6,INAVA,INHBA,IRF1,ISG15,KIF16B,KYNU,LCN2,METRNL,MS4A2,MUC12,NFE2L1,NFKB2,NFKBIA,NFKBIZ,NFX1,NLRC4,NLRP3,NPAS2,NUB1,NUPR1,PER1,PLA2G4C,PLK5,PPARG,PRDM1,PTGS2,PTX3,RELB,RIPK2,RSAD2,SIGLEC15,SLC7A2,SOCS1,SP100,STAT5A,TIFA,TNFAIP3,TNIP1,TNIP3,TREM1,TRIM38,TSLP,UNC13D,ZC3H12A |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 554 | 1994 | 80 | ACVR2B,ADORA2A,ADTRP,ANXA2P2,ARHGEF2,AURKC,BMP2,BMPR1B,BRAF,C5AR2,CCNG2,CDK20,CDK7,CDKN1B,CFLAR,CLK4,CNKSR3,CNPPD1,COPS8,CSF2,CSF3,CSNK1E,CXCL10,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,DYRK3,DYRK4,FGF2,GADD45B,GCNT2,GLYCTK,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,ITPRIP,LTBR,MAP3K20,MYDGF,NBR1,NCK1,NDUFS4,NEK3,NGF,NPHS1,NUAK2,PARP6,PER1,PIM3,PLAUR,PLK5,PRKAG1,PRLR,PTGS2,PTK6,RIPK2,S1PR2,SMAD2,SOCS1,SPINK1,ST3GAL1,TNFAIP3,TNIP1,TOM1L1,TRIB1,TRPM6,TSLP,VEGFA,WARS1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1724 | 73 | ACVR2B,ADTRP,ANXA2P2,ARHGEF2,BAG6,BBC3,BCL2L13,BIRC2,BMP2,BRAF,C5AR2,CCDC22,CDKN1B,CFLAR,CIRBP,COMMD1,COPS8,CSF2,CSF3,CSNK1E,DVL1,FGF2,FNTA,GADD45B,GCNT2,GSAP,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,IRF1,KRT17,LARP6,LTBR,MAGEC2,MAP3K20,MYDGF,NCK1,NFKBIA,NGF,NLRC4,NLRP3,NUB1,NUPR1,PARP6,PLAUR,PPARG,PRKAG1,PRLR,PTGS2,PTK6,RBM3,RIPK2,RNF144B,RNF185,S1PR2,SH3D19,SNAI2,SOCS1,STX5,TBC1D10A,TNFAIP3,TNIP1,TOM1L1,TRIB1,TSLP,VEGFA,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1825 | 75 | ACVR2B,ADORA2A,AMTN,ANXA2P2,ANXA3,ARF1,ARHGEF2,BAMBI,BIRC2,BMP2,BMPR1B,BTG1,C3AR1,CEBPB,CFLAR,CSF2,CSF3,CSNK1E,DDX58,DHX58,DUSP10,DVL1,ETS1,FGF2,GATM,GCNT2,GORAB,GSTO1,HCLS1,HDAC9,HMGA2,ICAM1,IDO1,IFIH1,IL1A,IL1B,IL6,INAVA,INHBA,IRF1,ISG15,JAG1,KRT17,LCN2,LINGO2,MYDGF,NCK1,NFKB2,NFKBIZ,NGF,NLRP3,NPAS2,PARP6,PLEK,PLK5,PPARG,PPIB,PRLR,PTGS2,PTK6,RIPK2,RSAD2,SMAD2,SOCS1,SOD2,STAT5A,STYXL1,TNFAIP3,TNFRSF12A,TRIB1,TSLP,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 0.0e+00 | 554 | 1210 | 59 | ARF1,ARHGEF2,BIRC2,CEBPB,CSF2,CSF3,CSF3R,CXCL1,CXCL10,DDX58,ETS1,FGF2,GBP4,GSTO1,HCLS1,ICAM1,IFIH1,IFIT1,IFIT2,IKBKG,IL13RA2,IL1A,IL1B,IL32,IL6,IRF1,ISG15,KIF16B,KRT18,KYNU,LCN2,LTBR,MMP1,MSC,NFKB2,NFKBIA,NUB1,PPARG,PRLR,PTGS2,PTPN12,RBCK1,RELB,RIPK2,RNF113A,RSAD2,SOCS1,SOD2,SP100,STAT5A,TNFAIP3,TNFRSF12A,TRAF1,TRIM38,TSLP,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 554 | 1779 | 72 | ADORA2A,AMZ1,ANXA2P2,ATE1,BAG6,BBC3,BCL2L13,BIRC2,CCDC22,CFLAR,COMMD1,COPS8,CRBN,CSNK1E,CTSW,DDX58,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,GSAP,HM13,IFIH1,IKBKG,IL1B,ISG15,LRIG2,MMP1,NFE2L1,NFKBIA,NGF,NLRC4,NLRP3,NUB1,NUPR1,OTUD1,OTUD6A,PLAUR,PPARG,PTGS2,RBCK1,RIPK2,RNF13,RNF144B,RNF148,RNF185,SEC11C,SERPINB10,SERPINB8,SH3D19,SIAH1,SMAD2,SPINK1,SPSB1,STAMBP,SUPT3H,TBC1D10A,TFPI2,TNFAIP3,TNFAIP8,TNIP1,TNIP3,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,VEGFA,VPS37C,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1428 | 64 | ACVR2B,AMTN,ANXA2P2,ANXA3,ARF1,ARG2,ARHGEF2,ARPC2,BAMBI,BMP2,BMPR1B,BTG1,C3AR1,CEBPB,CFLAR,CSF2,CSF3,CSNK1E,DUSP10,DVL1,ETS1,FGF2,GCNT2,GORAB,HCLS1,HDAC9,HMGA2,IDO1,IL1A,IL1B,IL6,INHBA,ISG15,JAG1,KRT17,LINGO2,METRNL,MYDGF,NCK1,NFKBIZ,NGF,NLRP3,PARP6,PLK5,PPARG,PPIB,PTGS2,PTK6,RBM4,RIPK2,S1PR2,SMAD2,SNAI2,SOCS1,SOD2,STYXL1,TNFAIP3,TNFRSF12A,TRIB1,UNC13D,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1880 | 74 | ACVR2B,ADORA2A,ADTRP,ANXA2P2,ARHGEF2,BIRC2,BMP2,BRAF,C5AR2,CCNG2,CDK7,CDKN1B,CFLAR,CNKSR3,CNPPD1,COMMD1,COPS8,CSF2,CSF3,CXCL10,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,FGF2,FNTA,GADD45B,GCNT2,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,ISG15,ITPRIP,LTBR,MAGEC2,MAP3K20,MYDGF,NBR1,NCK1,NDUFS4,NEK3,NGF,NUPR1,PARP6,PER1,PHACTR1,PLAUR,PPP4R1L,PRKAG1,PRLR,PTGS2,PTK6,RIPK2,S1PR2,SNAI2,SOCS1,SPINK1,STYXL1,TNFAIP3,TNIP1,TOM1L1,TRIB1,TSLP,VEGFA,WARS1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1710 | 70 | ARHGEF2,ARID3A,ATF6,BAMBI,BHLHA15,BIRC2,BMP2,BMPR1B,CCPG1,CDH13,CDK7,CEBPB,CIRBP,CSF3,CXCL10,DDX58,DVL1,EDF1,ELF3,ELF4,ETS1,ETS2,FGF2,HCLS1,HIVEP1,HMGA2,HOXB9,IKBKG,IKZF1,IL1A,IL1B,IL6,INHBA,IRF1,JAG1,JMY,KDM7A,LMO4,MEF2D,MLX,MYDGF,NCK1,NFE2L1,NFKB2,NFKBIA,NLRP3,NPAS2,NR3C1,NUPR1,PBX4,PER1,PPARG,PRDM7,PRDX6,RBM3,RELB,RIPK2,SFR1,SMAD2,SP100,STAT5A,SUPT3H,TBX6,TFE3,TNIP1,TNIP3,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 1124 | 56 | ADORA2A,ADTRP,ANXA2P2,ARG2,BIRC2,C3AR1,C5AR2,CDH13,CDKN1B,CEBPB,CXCL10,DDX58,DHX58,DUSP10,DVL1,ETS1,FGF2,FNTA,IDO1,IFIH1,IFIT1,IKBKG,IL1B,IL6,INAVA,IRF1,LRIG2,METRNL,MUC12,NFE2L1,NFKBIA,NFKBIZ,NLRC4,NLRP3,NUCB2,NUPR1,PER1,PLAUR,PLEK,PPARG,PTGS2,RELB,RIPK2,RSAD2,SLC7A2,SNAI2,SOCS1,TIFA,TNFAIP3,TNIP1,TNIP3,TRIB1,TRIM38,TSLP,VEGFA,ZC3H12A |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1823 | 72 | ACVR2B,ADORA2A,ADTRP,ANXA2P2,ARF1,ARHGEF2,BMP2,BRAF,C5AR2,CCNG2,CDK7,CDKN1B,CFLAR,CNKSR3,CNPPD1,COPS8,COX7A2L,CSF2,CSF3,CXCL10,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,FGF2,GADD45B,GCNT2,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,ITPRIP,LMO4,LTBR,MAP3K20,MYDGF,NBR1,NCK1,NDUFS4,NGF,NRBF2,NUPR1,PARP6,PER1,PHACTR1,PLAUR,PLEK,PPP4R1L,PRKAG1,PRLR,PTGS2,PTK6,RIPK2,S1PR2,SOCS1,SPINK1,STYXL1,TNFAIP3,TNIP1,TOM1L1,TRIB1,TSLP,VEGFA,WARS1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 1703 | 69 | ADORA2A,ADTRP,ANXA2P2,ARG2,ARHGEF2,BAMBI,BMP2,C5AR2,CCDC22,CDKN1B,CFLAR,CNKSR3,CSF2,DDIT4,DHX58,DUSP10,DUSP16,DUSP8,DVL1,DYRK3,ERLEC1,ETS1,FGF2,GSTO1,HMGA2,HYOU1,ICAM1,IL13RA2,IL1A,IL1B,IL6,ITPRIP,JAG1,LRIG2,MCTP1,METRNL,NCK1,NFKBIA,NLRP3,NUCB2,PEAR1,PER1,PIM3,PLAUR,PLEK,PPARG,PTGS2,PTK6,PTPN12,RNF113A,RNF169,S1PR2,SIAH1,SLC35F6,SMAD2,SNAI2,SOCS1,SOD2,SPINK1,STAMBP,TNFAIP3,TNIP1,TNIP3,TRIB1,TRIM38,UBE2J1,VEPH1,XBP1,ZC3H12A |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 1567 | 66 | ANXA3,ARF1,ARG2,ARHGEF2,BIRC2,BMP2,C15orf48,CCDC130,CEBPB,CFLAR,CMPK2,CSF2,CSF3,CXCL1,CXCL10,DDIT4,DDX58,DHX58,DUSP10,ELF4,GBP4,HMGA2,ICAM1,IDO1,IFIH1,IFIT1,IFIT2,IKBKG,IL1A,IL1B,IL6,INAVA,IRF1,ISG15,KIF16B,KYNU,LCN2,MUC12,NCK1,NFKB2,NFKBIA,NLRC4,NLRP3,NUB1,PLK5,PPARG,PRDM1,PTGS2,PTX3,RELB,RIPK2,RSAD2,SIGLEC15,SOCS1,SP100,TIFA,TNFAIP3,TNIP1,TNIP3,TREM1,TRIB1,TRIM38,TXNIP,UNC13D,XBP1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 554 | 1030 | 53 | ADORA2A,ARG2,ARHGEF2,BAG6,BIRC2,BRAF,CBX4,CDKN1B,CEBPB,CFLAR,CHMP4A,CPEB4,CSF2,CSF3,DYRK3,FCMR,FGF2,HCLS1,HMGA2,HYOU1,ICAM1,IDO1,IKBKG,IL1A,IL1B,IL6,ITPRIP,KRT18,MYDGF,NCK1,NFKBIA,NGF,NPAS2,NUAK2,NUPR1,PIM3,PLAUR,PRLR,PTGS2,RBCK1,RIPK2,RNF144B,SLC35F6,SNAI2,SOD2,STAMBP,TNFAIP3,TNFAIP8,TSC22D3,TSLP,VEGFA,XBP1,ZC3H12A |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 554 | 1625 | 67 | ACVR2B,ADORA2A,ADTRP,ANXA2P2,ARHGEF2,BMP2,BRAF,C5AR2,CCNG2,CDK7,CDKN1B,CFLAR,CNKSR3,CNPPD1,COPS8,COX7A2L,CSF2,CSF3,CXCL10,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,FGF2,GADD45B,GCNT2,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,ITPRIP,LMO4,LTBR,MAP3K20,MYDGF,NBR1,NCK1,NDUFS4,NGF,NRBF2,NUPR1,PARP6,PER1,PLAUR,PRKAG1,PRLR,PTGS2,PTK6,RIPK2,S1PR2,SOCS1,SPINK1,TNFAIP3,TNIP1,TOM1L1,TRIB1,TSLP,VEGFA,WARS1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 554 | 1174 | 56 | ADORA2A,ANXA2P2,ANXA3,APBA3,BHLHE40,BIRC2,CCDC22,CDKN1B,CFLAR,COMMD1,CPEB2,CSNK1E,DRD5,DUSP10,DUSP16,DUSP8,DVL1,FICD,GADD45B,GSTO1,HDAC9,HMGA2,IFIT1,IFIT2,IL1B,ITPRIP,NCK1,NFKBIA,NFKBIE,NGF,NLRP3,NUPR1,PHACTR1,PINLYP,PLAUR,PPARG,PTGS2,PTK6,PTX3,RBCK1,SERPINB10,SERPINB8,SOCS1,SP100,SPINK1,STYXL1,TBX6,TEN1,TFPI2,TNFAIP3,TNFAIP8,TRIB1,TXNIP,VEGFA,WARS1,ZC3H12A |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1670 | 67 | ADORA2A,ADTRP,ARG2,ARPC2,BAG6,BIRC2,BTN3A1,C17orf99,C3AR1,C5AR2,CEBPB,CSF2,CSF3,CSF3R,CXCL10,DDX58,DHX58,DUSP10,ETS1,HCLS1,ICAM1,IDO1,IFIH1,IFIT1,IKBKG,IL13RA2,IL1B,IL6,INAVA,INHBA,IRF1,ISG15,ITGA2B,JAG1,MAD1L1,MS4A2,MUC12,NCK1,NFKBIA,NFKBIZ,NLRC4,NLRP3,PPARG,PRAM1,PRDM1,RBCK1,RELB,RIPK2,RSAD2,SIGLEC15,SLC7A2,SOCS1,TFE3,TIFA,TNFAIP3,TNIP1,TNIP3,TREM1,TRIB1,TRIM38,TSC22D3,TSLP,UNC13D,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1870 | 71 | ANXA3,ARHGEF2,ARID3A,ATF6,BAMBI,BHLHA15,BIRC2,BMP2,BMPR1B,CCPG1,CDH13,CDK7,CEBPB,CIRBP,CSF3,CXCL10,DDX58,DVL1,EDF1,ELF3,ELF4,ETS1,ETS2,FGF2,HCLS1,HIVEP1,HMGA2,HOXB9,IKBKG,IKZF1,IL1A,IL1B,IL6,INHBA,IRF1,JAG1,JMY,KDM7A,LMO4,MEF2D,MLX,MYDGF,NCK1,NFE2L1,NFKB2,NFKBIA,NLRP3,NPAS2,NR3C1,NUPR1,PBX4,PER1,PPARG,PRDM7,PRDX6,RBM3,RELB,RIPK2,SFR1,SMAD2,SP100,STAT5A,SUPT3H,TBX6,TFE3,TNIP1,TNIP3,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 554 | 1781 | 69 | ACVR2B,ADAP1,ADAP2,ADPRH,ALOX5AP,ANXA2P2,ANXA3,ARF1,ARHGEF15,ARHGEF2,BAMBI,BBC3,BCL2L13,BMP2,BRAF,CDKN1B,CFLAR,CNKSR3,COPS8,CRBN,CSF3,CXCL1,DDX58,DNAJB11,DNAJC10,DRD5,DYNC1I2,EDF1,FGF2,FNTA,GADD45B,GNA15,GSTO1,HCLS1,HMGA2,ICAM1,IKBKG,IL1B,IL6,INAVA,JMY,KCTD7,LARP6,LMO4,MAGEC2,MAP3K20,NFKB2,NGF,NLRC4,NLRP3,NUPR1,OCRL,PARP6,PLAUR,PLEK,PPARG,PRKAG1,PRLR,RBCK1,RIPK2,S1PR2,SEC23B,SH3PXD2A,SOCS1,TBC1D10A,TOM1L1,TRAF1,TRIM38,VEGFA |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 554 | 1881 | 71 | ACVR2B,ANXA2P2,ARF1,ARHGEF2,ARPC2,BAMBI,BHLHA15,BHLHE40,BHLHE41,BIRC2,BMP2,BMPR1B,BTG1,CDKN1B,CEBPB,CFLAR,CSF2,CSF3,CSF3R,CSNK1E,CXCL10,DUSP10,DVL1,ESRP1,ETS1,FGF2,GCNT2,HCLS1,HDAC9,IL1B,IL6,INHBA,IRF1,ISG15,ITGA2B,JAG1,LMO4,LRIG2,METRNL,MEX3C,NBR1,NCK1,NFKBIA,NFKBIZ,NGF,NLRP3,PARP6,PHACTR1,PLK5,PPARG,PRDM1,PTGS2,PTK6,RBM4,RIPK2,S1PR2,SIGLEC15,SMAD2,SNAI2,SOCS1,SOD2,STYXL1,TBX6,TFE3,TNFRSF12A,TRIB1,UNC13D,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1988 | 73 | ARHGEF2,ARID3A,ATF6,BAMBI,BHLHA15,BIRC2,BMP2,BMPR1B,CCPG1,CDH13,CDK7,CEBPB,CIRBP,CSF3,CXCL10,DDX58,DVL1,EDF1,ELF3,ELF4,ETS1,ETS2,FGF2,HCLS1,HIVEP1,HMGA2,HOXB9,ICAM1,IKBKG,IKZF1,IL1A,IL1B,IL6,INHBA,IRF1,JAG1,JMY,KDM7A,KRT17,LARP6,LMO4,MEF2D,MLX,MYDGF,NCK1,NFE2L1,NFKB2,NFKBIA,NLRP3,NPAS2,NR3C1,NUPR1,PBX4,PER1,PPARG,PRDM7,PTGS2,PTX3,RBM3,RELB,RIPK2,SFR1,SMAD2,SP100,STAT5A,SUPT3H,TBX6,TFE3,TNIP1,TNIP3,VEGFA,XBP1,ZC3H12A |
| GO_INFLAMMATORY_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 765 | 44 | ADORA2A,BIRC2,BMP2,BMPR1B,C3AR1,C5AR2,CEBPB,CXCL1,CXCL10,DUSP10,ELF3,ETS1,HDAC9,ICAM1,IDO1,IKBKG,IL1A,IL1B,IL6,METRNL,MS4A2,NFE2L1,NFKB2,NFKBIA,NFKBIZ,NFX1,NLRC4,NLRP3,NUPR1,PER1,PLA2G4C,PPARG,PTGS2,PTX3,RELB,RIPK2,SLC7A2,TNFAIP3,TNIP1,TNIP3,TREM1,TSLP,UNC13D,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 554 | 1000 | 50 | ACVR2B,ANXA2P2,ARF1,ARHGEF2,ARPC2,BAMBI,BMP2,BMPR1B,BTG1,CEBPB,CFLAR,CSF2,CSF3,CSNK1E,DUSP10,DVL1,ETS1,FGF2,GCNT2,HCLS1,IL1B,IL6,INHBA,ISG15,JAG1,METRNL,NCK1,NFKBIZ,NGF,NLRP3,PARP6,PLK5,PPARG,PTGS2,PTK6,RBM4,RIPK2,S1PR2,SMAD2,SNAI2,SOCS1,SOD2,STYXL1,TNFRSF12A,TRIB1,UNC13D,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 554 | 1716 | 66 | ADORA2A,ANXA2P2,ARG2,ARHGEF2,BAG6,BAMBI,BIRC2,BMP2,BMPR1B,BTG1,C5AR2,CCPG1,CDH13,CDKN1B,CEBPB,CFLAR,COPS8,CSF2,CSF3,CXCL1,CXCL10,DUSP10,ETS1,FGF2,GCNT2,HCLS1,HMGA2,IDO1,IL1A,IL1B,IL6,INHBA,IRF1,JAG1,LAMC2,MAD1L1,MEF2D,MYDGF,NCK1,NDUFS4,NFKBIA,NGF,NUPR1,PHLDA2,PPARG,PRDM1,PTGS2,PTK6,PTPRK,RIPK2,S1PR2,SLC35F6,SMAD2,SNAI2,SOD2,STAMBP,STAT5A,TMEM115,TNFAIP3,TRIB1,TSLP,TXNIP,VEGFA,WARS1,XBP1,ZFP36L1 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 554 | 1863 | 69 | ARHGEF15,ARHGEF2,BBC3,BIRC2,BMP2,BRAF,C5AR2,CCDC22,CDH13,CFLAR,CNKSR3,COPS8,CSF3,DDIT4,DHX58,DUSP10,DUSP16,DUSP8,DYRK3,FBXO8,FGF2,GADD45B,GCNT2,GSTO1,HCLS1,HYOU1,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,JMY,JSRP1,LTBR,MAP3K20,MYDGF,NBR1,NCK1,NFKBIA,NGF,NLRP3,NUPR1,OCRL,PER1,PLAUR,PLEK,PRKAG1,PTGS2,RBCK1,RIPK2,RNF13,S1PR2,SIAH1,SNAI2,SOD2,SPINK1,STAMBP,STYXL1,TIFA,TNFAIP3,TNIP1,TNIP3,TRIB1,TRIM38,VEGFA,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 554 | 1198 | 54 | ARHGEF2,ARID3A,ATF6,BHLHA15,BMP2,BMPR1B,CCPG1,CDH13,CDK7,CEBPB,CSF3,CXCL10,DDX58,ELF3,ELF4,ETS1,ETS2,FGF2,HCLS1,HIVEP1,HMGA2,HOXB9,IKBKG,IKZF1,IL1A,IL1B,IL6,INHBA,IRF1,JAG1,LMO4,MEF2D,MLX,MYDGF,NCK1,NFE2L1,NFKB2,NFKBIA,NLRP3,NPAS2,NR3C1,PER1,PPARG,RELB,RIPK2,SMAD2,STAT5A,TBX6,TFE3,TNIP1,TNIP3,VEGFA,XBP1,ZC3H12A |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1935 | 70 | ACVR2B,ADORA2A,ALOXE3,AMPD3,ANXA2P2,ARF1,ATP6V0D2,BHLHA15,C3AR1,C5AR2,CCDC22,CEBPB,COMMD1,CXCL10,DNAJC10,DRAM2,DRD5,DYRK3,ETS1,FGF2,FLG2,GATM,GCNT2,GNA15,GSTO1,HCLS1,HDAC9,ICAM1,IFIT1,IKZF1,IL1A,IL1B,IL6,INAVA,INHBA,ISG15,JSRP1,KCNMA1,KCTD7,LCN2,METRNL,MEX3C,NFE2L1,ORMDL1,PDIA2,PDIA5,PIM3,PNPLA1,PPARG,PRDX6,PRLR,PTGS2,RPS17,SIGLEC15,SLC10A7,SLC11A2,SLC25A37,SLC30A7,SLC9A4,SLC9A8,SOD2,SP100,TEN1,TFE3,TNFAIP3,TSC22D3,TXNDC9,VEGFA,XBP1,ZFP36L1 |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 554 | 603 | 38 | ADORA2A,ARHGEF2,BAG6,BBC3,BMPR1B,CEBPB,CFLAR,CSF2,DDIT4,DEDD,DNAJC10,HRK,HYOU1,ICAM1,IL1A,IL1B,INHBA,ITPRIP,JMY,KRT18,LCN2,LTBR,NCK1,NGF,NUPR1,PLAUR,PTGS2,RBCK1,SIAH1,SLC35F6,SNAI2,SOD2,SP100,STYXL1,TNFAIP3,TNFRSF12A,TRAF1,XBP1 |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 554 | 1984 | 70 | ADORA2A,ADTRP,ANXA3,ARHGEF2,ARPC2,AVL9,BAMBI,BMP2,BMPR1B,BTG1,C3AR1,C5AR2,CATSPER3,CDH13,CFAP69,CSF3R,CXCL1,CXCL10,DDIT4,DDX58,DNER,DUSP10,DVL1,ETS1,FERMT3,FGF2,GCNT2,HDAC9,HOXB9,ICAM1,IL1A,IL1B,IL6,IQCG,ITGA2B,JAG1,JMY,LAMB3,LAMC2,LMO4,LRIG2,LRP12,MCTP1,MMP1,NCK1,PHACTR1,PHLDA2,PLAUR,PPARG,PSTPIP2,PTGS2,PTK6,PTPRK,RND1,ROBO3,S100P,SIAH1,SNAI2,SOD2,SP100,STAT5A,TMEFF1,TNFAIP3,TNFRSF12A,TREM1,TRIB1,TSPAN1,VEGFA,XBP1,ZC3H12A |
| GO_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 554 | 1442 | 58 | ADORA2A,AMPD3,ANXA3,ARG2,BAG6,BRI3,BTN3A1,C17orf99,C3AR1,CEBPB,CSF2,CXCL1,CXCL10,DUSP10,ELF4,FERMT3,FLG2,GNA15,HDAC9,ICAM1,IDO1,IKZF1,IL13RA2,IL1B,IL6,INHBA,IRF1,ITGA2B,LCN2,LMO4,LTBR,MAD1L1,NCK1,NFKB2,NFKBIZ,NLRP3,PDXK,PEAR1,PLAUR,PLEK,PRAM1,PRDM1,PRDX6,PRLR,PTX3,RELB,RIPK2,RSAD2,S100P,SERPINB10,SLC7A2,SOCS1,TNFAIP3,TSLP,UNC13D,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 554 | 737 | 41 | ADCY10,ADORA2A,ARHGEF2,ATF6,BBC3,BCL2L13,BMP2,BMPR1B,BTG1,CDKN1B,CFLAR,DDIT4,GADD45B,HMGA2,HRK,IDO1,IFIT2,IL6,INHBA,JMY,KCNMA1,LTBR,MAP3K20,NCK1,NGF,NLRC4,NLRP3,NUPR1,PLAUR,PPARG,PTGS2,RBCK1,RIPK2,SIAH1,SOD2,STYXL1,SYCE3,TNFAIP8,TNFRSF12A,TXNIP,ZC3H12A |
| GO_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 433 | 32 | ANXA3,ARHGEF2,BHLHE40,C14orf39,CCDC22,CFLAR,COMMD1,CSF3,DDX58,HCLS1,ICAM1,IKBKG,IL1B,IL6,JMY,NFKB2,NFKBIA,NFKBIE,NLRC4,NLRP3,NUPR1,PPARG,RBCK1,RIPK2,SP100,TBX6,TNFAIP3,TRAF1,TRIB1,TRIM38,VEGFA,ZC3H12A |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 554 | 791 | 42 | ARF1,BIRC2,CSF2,CSF3,CSF3R,CXCL1,CXCL10,FGF2,GSTO1,ICAM1,IFIT1,IFIT2,IKBKG,IL13RA2,IL1A,IL1B,IL32,IL6,IRF1,ISG15,KRT18,LCN2,LTBR,MMP1,NFKBIA,PPARG,PRLR,PTGS2,RBCK1,RIPK2,RNF113A,RSAD2,SOCS1,SOD2,SP100,STAT5A,TNFAIP3,TNFRSF12A,TRAF1,TRIM38,TSLP,VEGFA |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 554 | 1869 | 66 | ACVR2B,ADORA2A,ANXA2P2,ATF6,BAMBI,BBC3,BIRC2,BMP2,BMPR1B,BRAF,C5AR2,CCDC22,CDH13,CFLAR,COPS8,CSF2,CSF3,CSNK1E,DHX58,DVL1,ELF3,FGF2,GADD45B,GCNT2,GORAB,GSTO1,HCLS1,HRK,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,JAG1,LTBR,MAP3K20,MYDGF,NCK1,NGF,NUPR1,PLAUR,PRLR,PTGS2,PTK6,RBCK1,RIPK2,RNF13,RSAD2,S1PR2,SH2D2A,SIAH1,SLC35C2,SMAD2,SOCS1,SRARP,STYXL1,TIFA,TNFAIP3,TNFRSF12A,TRIM38,TSLP,VEGFA,XBP1,ZC3H12A |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 554 | 1758 | 63 | ADTRP,ANXA3,ARHGEF2,ARPC2,AVL9,BAMBI,BMP2,BTG1,C3AR1,C5AR2,CATSPER3,CDH13,CFAP69,CSF3R,CXCL1,CXCL10,DDIT4,DDX58,DNER,DUSP10,ETS1,FERMT3,FGF2,GCNT2,HDAC9,HOXB9,ICAM1,IL1A,IL1B,IL6,IQCG,ITGA2B,JAG1,JMY,LAMB3,LAMC2,LMO4,LRIG2,LRP12,MCTP1,MMP1,NCK1,PHACTR1,PHLDA2,PPARG,PSTPIP2,PTGS2,PTK6,PTPRK,RND1,S100P,SNAI2,SOD2,SP100,STAT5A,TNFAIP3,TNFRSF12A,TREM1,TRIB1,TSPAN1,VEGFA,XBP1,ZC3H12A |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 554 | 1698 | 61 | ACVR2B,ARHGEF2,ATP6V0D2,BIRC2,BTG1,CATSPER3,CDKN1B,CEBPB,CFLAR,CMPK2,CPEB2,CPEB4,CSF2,CSF3,CXCL1,CXCL10,DDIT4,DRD5,DUSP10,ETS1,GNA15,HDAC9,ICAM1,IDO1,IL1A,IL1B,IL6,INAVA,INHBA,JAG1,KCNMA1,KLF3,LCN2,NCK1,NDUFS4,NFE2L1,NFKB2,NFKBIA,NLRP3,NR3C1,PER1,PIM3,PPARG,PRLR,PTGS2,PTK6,PTPRK,RIPK2,SMAD2,SNAI2,SOCS1,SOD2,STAT5A,TNFAIP3,TNIP3,TRIB1,TRIML2,TXNIP,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1187 | 50 | ARPC2,BAG6,BIRC2,BTN3A1,C17orf99,C3AR1,C5AR2,CSF3,CXCL10,DDX58,DHX58,DUSP10,ETS1,HCLS1,ICAM1,IDO1,IFIH1,IKBKG,IL13RA2,IL1B,IL6,INAVA,INHBA,IRF1,ISG15,ITGA2B,JAG1,MUC12,NCK1,NFKBIA,NFKBIZ,NLRC4,NLRP3,PRAM1,RBCK1,RELB,RIPK2,RSAD2,SOCS1,TIFA,TNFAIP3,TNIP1,TNIP3,TRIB1,TSLP,UNC13D,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1189 | 50 | ADORA2A,ANXA2P2,ASB1,BAG6,BIRC2,CDKN1B,CFLAR,CIRBP,CNKSR3,CPEB2,CPEB4,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,EIF4EBP3,ERLEC1,GADD45B,IL1B,IL6,INHBA,ISG15,ITPRIP,LRIG2,NCK1,NGF,PER1,PHACTR1,PLAUR,PTGS2,PTK6,PTX3,RBM4,SERPINB10,SERPINB8,SOCS1,SPINK1,STYXL1,TFPI2,TNFAIP3,TNFAIP8,TNIP1,TRIB1,UBE2J1,VEGFA,WARS1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 554 | 735 | 39 | ADORA2A,ANXA2P2,BAG6,BBC3,BCL2L13,BIRC2,CCDC22,CFLAR,COMMD1,CSNK1E,DVL1,ERLEC1,GSAP,IL1B,LRIG2,NFE2L1,NGF,NLRC4,NLRP3,NUB1,NUPR1,PLAUR,PPARG,PTGS2,RIPK2,RNF144B,RNF185,SERPINB10,SERPINB8,SH3D19,SPINK1,TBC1D10A,TFPI2,TNFAIP8,TNIP1,TRIB1,UBE2J1,VEGFA,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 823 | 41 | ADORA2A,ANXA2P2,ANXA3,APBA3,BIRC2,CDKN1B,CFLAR,CPEB2,DRD5,DUSP10,DUSP16,DUSP8,DVL1,FICD,GADD45B,HDAC9,IFIT1,IL1B,ITPRIP,NCK1,NGF,PHACTR1,PINLYP,PLAUR,PPARG,PTGS2,PTK6,PTX3,SERPINB10,SERPINB8,SOCS1,SPINK1,STYXL1,TEN1,TFPI2,TNFAIP3,TNFAIP8,TRIB1,TXNIP,VEGFA,WARS1 |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 554 | 1680 | 60 | ACVR2B,ADORA2A,ADTRP,AMPD3,ANXA3,ARF1,ARG2,BRI3,BTN3A1,C3AR1,C5AR2,CSF2,CTSW,CXCL1,DDX58,DVL1,FERMT3,FLG2,HDAC9,IFIH1,IL13RA2,IL1A,IL1B,IL6,INHBA,ISG15,ITGA2B,LCN2,MANF,MCTP1,MIA2,NLRC4,NLRP3,NPHS1,PDXK,PIM3,PLAUR,PLEK,PRAM1,PRDX6,PRLR,PTX3,RAB5A,RIPK2,RSAD2,S100P,SERPINB10,SLC9A4,SMAD2,SOCS1,STAT5A,TMED10,TNFAIP2,TNFAIP3,TSLP,UNC13D,USE1,VEGFA,XBP1,ZC3H12A |
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 554 | 1894 | 64 | ADORA2A,ADTRP,ANXA2P2,ARF1,ARG2,BBC3,BET1L,BRAF,C5AR2,CATSPER3,CDH13,CEBPB,CNKSR3,COMMD1,CRBN,CXCL10,DDX58,DVL1,ERLEC1,GRM6,GSTO1,HCLS1,HDAC9,ICAM1,IFIH1,IL13RA2,IL1A,IL1B,IL6,INHBA,JSRP1,KCNH6,KCNMA1,KCNQ3,KCTD7,LMAN2,MCTP1,NFKBIA,NLRP3,NPHS1,PER1,PIM3,PPARG,PRAM1,PTGS2,PTX3,RAB5A,RBM4,RIPK2,RSAD2,SCN11A,SLC35F6,SOCS1,SP100,SPINK1,TNFAIP3,TOMM7,TSLP,TSPAN1,UBE2J1,UNC13D,VEGFA,XBP1,ZC3H12A |
| GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 554 | 408 | 29 | ADORA2A,ARHGEF2,BBC3,BMPR1B,CFLAR,CSF2,HRK,HYOU1,ICAM1,IL1A,IL1B,INHBA,ITPRIP,LTBR,NCK1,NUPR1,PLAUR,PTGS2,RBCK1,SIAH1,SLC35F6,SNAI2,SOD2,SP100,STYXL1,TNFAIP3,TNFRSF12A,TRAF1,XBP1 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 804 | 40 | ADORA2A,ARG2,BIRC2,CEBPB,DDX58,DHX58,DUSP10,ETS1,IDO1,IFIH1,IFIT1,IKBKG,IL1B,IL6,INAVA,IRF1,METRNL,MUC12,NFE2L1,NFKBIA,NFKBIZ,NLRC4,NLRP3,NPAS2,NUPR1,PER1,PPARG,PTGS2,RELB,RIPK2,RSAD2,SLC7A2,SOCS1,TIFA,TNFAIP3,TNIP1,TNIP3,TRIM38,TSLP,ZC3H12A |
| GO_RESPONSE_TO_LIPID | 0.0e+00 | 0.0e+00 | 554 | 930 | 43 | ADTRP,ANXA3,CATSPER3,CDK7,CDKN1B,CEBPB,CFLAR,CMPK2,CSF2,CSF3,CXCL1,CXCL10,DDIT4,DUSP10,ETS1,ICAM1,IDO1,IL1A,IL1B,IL6,INHBA,LCN2,NFE2L1,NFKB2,NFKBIA,NLRP3,NR3C1,PER1,PPARG,PTGS2,PTK6,RIPK2,SMAD2,SNAI2,SRARP,TNFAIP3,TNIP3,TRIB1,TRIML2,TXNIP,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 554 | 1427 | 54 | ARF1,ARHGEF2,BAMBI,BMP2,CCDC22,CFLAR,CNKSR3,CSF2,DDIT4,DHX58,DRD5,DUSP10,DUSP16,DUSP8,DVL1,DYRK3,GSTO1,HYOU1,ICAM1,IL1A,IL1B,IL6,INHBA,ITPRIP,JAG1,NCK1,NFKBIA,NLRP3,PEAR1,PER1,PIM3,PLAUR,PLEK,PPARG,PTGS2,PTK6,PTPN12,RNF113A,S1PR2,SIAH1,SLC35F6,SMAD2,SNAI2,SOCS1,SOD2,SPINK1,STAMBP,TNFAIP3,TNIP1,TNIP3,TRIB1,VEPH1,XBP1,ZC3H12A |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 554 | 990 | 44 | ANXA2P2,C17orf99,CEBPB,CSF2,CSF3,CSF3R,DUSP10,DYRK3,ETS1,HCLS1,HDAC9,IDO1,IKZF1,IL6,INHBA,IRF1,ISG15,ITGA2B,JAG1,LMO4,LTBR,MAD1L1,NFE2L1,NFKB2,NFKBIA,NFKBIZ,NLRP3,PLEK,PPARG,PRDM1,RELB,RIPK2,RSAD2,SH3PXD2A,SIGLEC15,SLC11A2,SOCS1,TFE3,TNFAIP3,TRIB1,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 0.0e+00 | 554 | 1135 | 47 | ADORA2A,ADTRP,ARHGEF2,ATP6V0D2,BAG6,BIRC2,BTG1,CDH13,CDKN1B,CEBPB,CFLAR,CPEB2,CPEB4,DDX58,DNAJC10,DRD5,ERLEC1,GNA15,HDAC9,HM13,ICAM1,IFIH1,IFIT1,IL1B,IL6,INAVA,JAG1,KLF3,KYNU,NCK1,NDUFS4,NFKBIA,NLRP3,PER1,PPARG,PRLR,PTGS2,RIPK2,RNF185,SOCS1,STAT5A,TMED10,TNFAIP3,UBE2J1,UQCRC1,XBP1,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1247 | 49 | ACVR2B,ADTRP,ANXA2P2,ARHGEF2,BIRC2,BMP2,BRAF,C5AR2,CDKN1B,CFLAR,COMMD1,COPS8,CSF2,CSF3,DVL1,FGF2,FNTA,GADD45B,GCNT2,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,LTBR,MAGEC2,MAP3K20,MYDGF,NGF,NUPR1,PARP6,PLAUR,PRKAG1,PRLR,PTGS2,PTK6,RIPK2,S1PR2,SNAI2,SOCS1,TNIP1,TOM1L1,TSLP,VEGFA,ZC3H12A |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1410 | 52 | ANXA2P2,ATE1,BAG6,BIRC2,CCDC22,CDKN1B,CECR2,CIRBP,COMMD1,CRBN,CSNK1E,CTSW,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,FGF2,HM13,IL1B,IL6,ISG15,KIF16B,LRIG2,MAGEC2,NFE2L1,NUB1,NUPR1,PATL1,RBCK1,RNF13,RNF144B,RNF148,RNF185,RPL41,RPS17,SH3D19,SIAH1,SPSB1,STX5,TNFAIP3,TNPO1,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,USE1,VPS37C,XBP1,ZC3H12A,ZFP36L1 |
| GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 0.0e+00 | 0.0e+00 | 554 | 1200 | 47 | ANXA3,ARG2,ARHGEF2,BIRC2,CEBPB,CXCL10,DDIT4,DDX58,DHX58,DUSP10,ELF4,GBP4,ICAM1,IFIH1,IFIT1,IFIT2,IKBKG,IL1B,IL6,INAVA,IRF1,ISG15,KIF16B,KYNU,LCN2,MUC12,NFKBIA,NLRC4,NLRP3,NUB1,PPARG,PRDM1,PTX3,RELB,RIPK2,RSAD2,SIGLEC15,SOCS1,SP100,TIFA,TNFAIP3,TNIP1,TNIP3,TREM1,TRIM38,UNC13D,ZC3H12A |
| GO_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 938 | 41 | ANXA2P2,ATE1,BAG6,BIRC2,CCDC22,CDKN1B,COMMD1,CRBN,CSNK1E,CTSW,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,HM13,IL1B,ISG15,LRIG2,MAGEC2,NFE2L1,NUB1,NUPR1,RBCK1,RNF13,RNF144B,RNF148,RNF185,SH3D19,SIAH1,SPSB1,STX5,TNFAIP3,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,USE1,VPS37C,XBP1 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 554 | 1114 | 45 | ASB1,BIRC2,CBX4,CCDC22,COMMD1,COPS8,CRBN,DCAF10,DDX58,FBXL13,IFIH1,IKBKG,INAVA,ISG15,MAGEC2,NFE2L1,NFKBIA,NFX1,NLRP3,NUB1,OTUD1,OTUD6A,RBCK1,RIPK2,RNF113A,RNF13,RNF144B,RNF148,RNF169,RNF185,SIAH1,SMAD2,SOCS1,SPSB1,STAMBP,SUPT3H,TNFAIP3,TNIP1,TNIP3,TRIM38,TRIML2,UBE2E1,UBE2F,UBE2J1,ZC3H12A |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 554 | 1175 | 46 | ACVR2B,ADAP2,ADTRP,ANXA2P2,ANXA3,ARHGEF15,BMP2,BTG1,C3AR1,CDH13,CDKN1B,CFLAR,CXCL10,DNAAF1,DVL1,ETS1,FGF2,HDAC9,HMGA2,IL1A,IL1B,IL6,JAG1,LMO4,MEF2D,MYDGF,NOTO,PDLIM4,PPARG,PRDM1,PTGS2,QKI,SH2D2A,SMAD2,SNAI2,SOD2,SP100,TBX6,TNFAIP2,TNFAIP3,TNFRSF12A,VEGFA,WARS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 0.0e+00 | 0.0e+00 | 554 | 288 | 23 | ATF6,BAG6,BBC3,BHLHA15,CEBPB,DNAJB11,DNAJC10,ERLEC1,FICD,HM13,HYOU1,MANF,MYDGF,NCK1,NFE2L1,NRBF2,NUPR1,PARP6,PDIA2,PDIA5,RNF185,UBE2J1,XBP1 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 554 | 751 | 36 | ARG2,ARHGEF2,ATF6,BAG6,BMP2,DUSP10,DYRK3,ERLEC1,FICD,GADD45B,HMGA2,HYOU1,IL1A,IL1B,INAVA,LRIG2,LTBR,MANF,MAP3K20,NBR1,NCK1,NFE2L1,NPAS2,NUPR1,PER1,PTGS2,RIPK2,RNF13,RNF169,RNF185,SNAI2,SOD2,UBE2J1,VEGFA,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1146 | 45 | ACVR2B,ADTRP,ANXA2P2,ARHGEF2,BMP2,BRAF,C5AR2,CDKN1B,CFLAR,COPS8,CSF2,CSF3,DVL1,FGF2,GADD45B,GCNT2,HCLS1,HMGA2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,LMO4,LTBR,MAP3K20,MYDGF,NGF,NUPR1,PARP6,PLAUR,PLEK,PRKAG1,PRLR,PTGS2,PTK6,RIPK2,S1PR2,SOCS1,TOM1L1,TSLP,VEGFA,ZC3H12A |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 976 | 41 | ACVR2B,ADORA2A,BMP2,BRAF,CCNG2,CDK7,CDKN1B,CNPPD1,COPS8,CXCL10,DUSP10,DUSP16,DUSP8,DVL1,FGF2,GADD45B,HMGA2,IKBKG,IL1B,INAVA,ITPRIP,LMO4,MAGEC2,MAP3K20,NCK1,NGF,NRBF2,PARP6,PPARG,PRKAG1,PRLR,PTK6,RIPK2,S1PR2,SOCS1,TEN1,TNFAIP3,TOM1L1,TRIB1,VEGFA,WARS1 |
| GO_CYTOKINE_PRODUCTION | 0.0e+00 | 0.0e+00 | 554 | 808 | 37 | ARG2,ARHGEF2,ASB1,BIRC2,BTN3A1,C3AR1,C5AR2,CEBPB,CSF2,DDX58,DHX58,HDAC9,IDO1,IFIH1,IL1A,IL1B,IL6,INAVA,INHBA,IRF1,ISG15,NFKB2,NLRC4,NLRP3,PER1,PTGS2,RELB,RIPK2,RSAD2,SNAI2,SOCS1,TNFAIP3,TRIM38,TSLP,UBE2J1,XBP1,ZC3H12A |
| GO_TUBE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 554 | 1122 | 44 | ACVR2B,ADTRP,ANXA2P2,ANXA3,ARG2,BAG6,BMP2,BTG1,C3AR1,CDH13,CXCL10,DNAAF1,DVL1,ETS1,FGF2,GORAB,HDAC9,HMGA2,HSD11B1,IL1A,IL1B,IL6,JAG1,LMO4,MYDGF,NOTO,PPARG,PRDM1,PTGS2,PTK6,QKI,SH2D2A,SMAD2,SP100,TBX6,TNFAIP2,TNFAIP3,TNFRSF12A,VEGFA,WARS1,XBP1,YIPF6,ZC3H12A,ZFP36L1 |
| GO_CELLULAR_RESPONSE_TO_LIPID | 0.0e+00 | 0.0e+00 | 554 | 615 | 32 | ADTRP,CDK7,CEBPB,CFLAR,CMPK2,CSF2,CSF3,CXCL1,CXCL10,DDIT4,ICAM1,IL1A,IL1B,IL6,INHBA,LCN2,NFE2L1,NFKBIA,NLRP3,NR3C1,PER1,PPARG,PTK6,RIPK2,SNAI2,SRARP,TNFAIP3,TNIP3,TRIB1,XBP1,ZC3H12A,ZFP36L1 |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 554 | 1177 | 45 | ACVR2B,ADTRP,AMTN,ANXA2P2,ANXA3,BMP2,BTG1,C3AR1,CDH13,CFLAR,CSF3R,CXCL10,DVL1,ETS1,ETS2,FGF2,HDAC9,HMGA2,IL1A,IL1B,IL6,INHBA,JAG1,KIF16B,LAMB3,LMO4,MYDGF,NFKB2,NPHS1,PPARG,PTGS2,SH2D2A,SH3PXD2A,SMAD2,SNAI2,SP100,TBX6,TNFAIP2,TNFAIP3,TNFRSF12A,UNC13D,VEGFA,WARS1,XBP1,ZC3H12A |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 1721 | 56 | ACVR2B,ADTRP,ANXA3,ARHGEF2,ATP6V0D2,BAMBI,BMP2,BMPR1B,BTG1,CATSPER3,CDH13,CDK7,CDKN1B,CEBPB,CFLAR,CPEB2,CPEB4,DDIT4,DRD5,ESRP1,ETS1,FERMT2,FGF2,FNTA,GCNT2,GNA15,HCLS1,HDAC9,HIVEP1,ICAM1,IL1B,IL6,INHBA,KIF16B,KLF3,NCK1,NGF,NLRP3,NR3C1,PER1,PPARG,PRLR,PTGS2,PTPN12,PTPRK,RIPK2,SLC33A1,SMAD2,SNAI2,SOCS1,SRARP,STAT5A,TXNIP,VEPH1,XBP1,ZFP36L1 |
| GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 554 | 223 | 20 | ARHGEF2,BMPR1B,CFLAR,CSF2,DEDD,ICAM1,IL1A,IL1B,INHBA,ITPRIP,KRT18,LCN2,LTBR,NGF,RBCK1,SNAI2,SP100,TNFAIP3,TNFRSF12A,TRAF1 |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 554 | 1425 | 50 | ADORA2A,ADTRP,AMTN,ARG2,ARPC2,BMP2,CDH13,CEBPB,CLDN12,CSF3R,DUSP10,ETS1,FERMT2,FERMT3,FLG2,GCNT2,ICAM1,IDO1,IL1B,IL32,IL6,IRF1,ITGA2B,JAG1,KRT18,LAMB3,LAMC2,MAD1L1,NCK1,NFKBIZ,NLRP3,NPHS1,PCDHGA8,PEAR1,PLEK,PTPRK,RIPK2,RND1,ROBO3,SERPINB8,SNAI2,SOCS1,TFE3,TNFRSF12A,TNIP1,UNC13D,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_KINASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 872 | 38 | ACVR2B,ADORA2A,BMP2,BRAF,CCNG2,CDK7,CDKN1B,CNPPD1,COPS8,CXCL10,DUSP10,DUSP16,DUSP8,DVL1,FGF2,GADD45B,HMGA2,IKBKG,IL1B,INAVA,ITPRIP,LMO4,MAP3K20,NCK1,NGF,NRBF2,PARP6,PRKAG1,PRLR,PTK6,RIPK2,S1PR2,SOCS1,TNFAIP3,TOM1L1,TRIB1,VEGFA,WARS1 |
| GO_LEUKOCYTE_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 554 | 520 | 29 | ANXA2P2,C17orf99,CEBPB,CSF2,CSF3,DUSP10,HCLS1,HDAC9,IKZF1,IL6,INHBA,IRF1,LTBR,NFKBIZ,NLRP3,PPARG,PRDM1,RELB,RIPK2,RSAD2,SH3PXD2A,SIGLEC15,SOCS1,TFE3,TRIB1,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1301 | 47 | AMPD3,ANXA2P2,ARG2,ATE1,BAG6,BIRC2,CCDC22,CDKN1B,COMMD1,CRBN,CSNK1E,CTSW,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,FGF2,HM13,IDO1,IL1B,ISG15,KYNU,LRIG2,MAGEC2,NFE2L1,NUB1,NUPR1,RBCK1,RNF13,RNF144B,RNF148,RNF185,SH3D19,SIAH1,SPSB1,STX5,TNFAIP3,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,UPP1,USE1,VPS37C,XBP1 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 554 | 1208 | 45 | ARHGEF2,ATP6V0D2,CEBPB,CFLAR,CMPK2,CPEB2,CPEB4,CSF2,CSF3,CXCL1,CXCL10,DDIT4,DRD5,ETS1,GNA15,HDAC9,ICAM1,IL1A,IL1B,IL6,INHBA,KLF3,LCN2,NCK1,NFE2L1,NFKBIA,NLRP3,NR3C1,PIM3,PPARG,PRLR,PTGS2,PTK6,PTPRK,RIPK2,SNAI2,SOCS1,SOD2,STAT5A,TNFAIP3,TNIP3,TRIB1,XBP1,ZC3H12A,ZFP36L1 |
| GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | 0.0e+00 | 0.0e+00 | 554 | 358 | 24 | CEBPB,CMPK2,CSF2,CSF3,CXCL1,CXCL10,DUSP10,ICAM1,IDO1,IL1A,IL1B,IL6,INAVA,LCN2,NFKB2,NFKBIA,NLRP3,PTGS2,RIPK2,TNFAIP3,TNIP3,TRIB1,XBP1,ZC3H12A |
| GO_RESPONSE_TO_VIRUS | 0.0e+00 | 0.0e+00 | 554 | 328 | 23 | ARF1,BIRC2,CCDC130,CXCL10,DDIT4,DDX58,DHX58,HMGA2,IFIH1,IFIT1,IFIT2,IKBKG,IL1B,IL6,IRF1,ISG15,LCN2,NLRP3,RSAD2,TNFAIP3,TRIM38,UNC13D,ZC3H12A |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1180 | 44 | ANXA2P2,ATE1,BAG6,BIRC2,CCDC22,CECR2,CIRBP,COMMD1,CRBN,CSNK1E,CTSW,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,HM13,IL6,ISG15,MAGEC2,NFE2L1,NUB1,NUPR1,PATL1,RBCK1,RNF13,RNF144B,RNF148,RNF185,RPL41,RPS17,SIAH1,SPSB1,TNFAIP3,TNPO1,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,VPS37C,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 1429 | 49 | ACVR2B,ADAP1,ADAP2,ADPRH,ALOX5AP,ARF1,ARHGEF15,BBC3,BCL2L13,BMP2,BRAF,CDKN1B,CFLAR,COPS8,CXCL1,DNAJB11,DNAJC10,DRD5,DYNC1I2,FGF2,FNTA,GADD45B,GNA15,HMGA2,ICAM1,IKBKG,IL1B,INAVA,LMO4,MAGEC2,MAP3K20,NGF,NLRC4,NLRP3,NUPR1,OCRL,PARP6,PLEK,PPARG,PRKAG1,PRLR,RIPK2,S1PR2,SEC23B,SH3PXD2A,SOCS1,TBC1D10A,TOM1L1,VEGFA |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 782 | 35 | ANXA2P2,ATE1,BAG6,BIRC2,CCDC22,COMMD1,CRBN,CSNK1E,CTSW,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,HM13,ISG15,MAGEC2,NFE2L1,NUB1,NUPR1,RBCK1,RNF13,RNF144B,RNF148,RNF185,SIAH1,SPSB1,TNFAIP3,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,VPS37C,XBP1 |
| GO_INNATE_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 1005 | 40 | ARG2,ARHGEF2,BIRC2,DDX58,DHX58,DUSP10,ELF4,GBP4,ICAM1,IFIH1,IFIT1,IFIT2,IKBKG,INAVA,IRF1,ISG15,KIF16B,KYNU,LCN2,MUC12,NFKBIA,NLRC4,NLRP3,NUB1,PPARG,PRDM1,PTX3,RELB,RIPK2,RSAD2,SIGLEC15,SOCS1,SP100,TIFA,TNFAIP3,TNIP1,TNIP3,TREM1,TRIM38,UNC13D |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1859 | 57 | ADCY10,ALG12,ALOXE3,AMPD3,ARG2,ATP5MGL,B3GNT5,B3GNT6,BMPR1B,CEBPB,CIRBP,CMPK2,COG3,CPEB2,CPEB4,EIF4EBP3,FTSJ1,GATM,GCNT2,GSTO1,GUK1,IDO1,IL1A,IL1B,IL6,INHBA,KRT17,KYNU,LARP6,MRPS24,MUC12,NCK1,NFE2L1,ORMDL1,OSTC,PDXK,PER1,PPARG,PTGS2,QKI,RBM3,RBM4,RPL41,RPS17,SLC10A7,SLC11A2,SLC35C2,ST3GAL1,ST6GAL1,TMEM115,TMLHE,TNIP1,UBE2J1,UPP1,WARS1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 0.0e+00 | 554 | 1107 | 42 | ADTRP,ANXA3,ARHGEF2,BMP2,C3AR1,C5AR2,CDH13,CDKN1B,CFAP69,CXCL10,DDX58,DNAAF1,DUSP10,ETS1,FERMT3,FGF2,GCNT2,HDAC9,ICAM1,IL1B,IL6,ITGA2B,JAG1,LAMC2,LMO4,LRIG2,MCTP1,NCK1,PHACTR1,PHLDA2,PPARG,PTGS2,PTPRK,RND1,SNAI2,SOD2,SP100,STAT5A,TRIB1,VEGFA,XBP1,ZC3H12A |
| GO_RESPONSE_TO_BACTERIUM | 0.0e+00 | 0.0e+00 | 554 | 711 | 33 | ANXA3,ARG2,BMP2,C15orf48,CEBPB,CFLAR,CMPK2,CSF2,CSF3,CXCL1,CXCL10,DHX58,DUSP10,GBP4,ICAM1,IDO1,IL1A,IL1B,IL6,INAVA,ISG15,LCN2,NFKB2,NFKBIA,NLRC4,NLRP3,PTGS2,RIPK2,TNFAIP3,TNIP3,TRIB1,XBP1,ZC3H12A |
| GO_TUBE_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 554 | 928 | 38 | ACVR2B,ADTRP,ANXA2P2,ANXA3,BMP2,BTG1,C3AR1,CDH13,CXCL10,DNAAF1,DVL1,ETS1,FGF2,HDAC9,HMGA2,IL1A,IL1B,IL6,JAG1,LMO4,MYDGF,NOTO,PPARG,PRDM1,PTGS2,QKI,SH2D2A,SMAD2,SP100,TBX6,TNFAIP2,TNFAIP3,TNFRSF12A,VEGFA,WARS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 249 | 20 | CEBPB,CMPK2,CSF2,CSF3,CXCL1,CXCL10,ICAM1,IL1A,IL1B,IL6,LCN2,NFKBIA,NLRP3,RIPK2,TNFAIP3,TNIP3,TRIB1,TXNIP,XBP1,ZC3H12A |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 0.0e+00 | 0.0e+00 | 554 | 974 | 39 | ADCY10,ASB1,AURKC,BAG6,BIRC2,BMPR1B,BTG1,C14orf39,CATSPER3,CDKN1B,CEBPB,CFAP69,CSF2,DEDD,ICAM1,IL1A,IL1B,INHBA,IQCG,MEI1,MOV10L1,NUPR1,PHLDA2,PPARG,PRDM1,PRKAG1,PTGS2,PTX3,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,TCF23,UBE2J1,VEGFA,ZFP36L1,ZNF449 |
| GO_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 1116 | 42 | ARG2,ARPC2,BAG6,BIRC2,BTN3A1,C17orf99,C3AR1,C5AR2,DDX58,DHX58,DUSP10,ICAM1,IDO1,IFIH1,IKBKG,IL13RA2,IL1B,IL6,INAVA,IRF1,MS4A2,MUC12,NCK1,NFKBIA,NFKBIZ,NLRC4,NLRP3,PPARG,PRAM1,RBCK1,RELB,RIPK2,RSAD2,SOCS1,TIFA,TNFAIP3,TNIP1,TNIP3,TREM1,UNC13D,XBP1,ZC3H12A |
| GO_REGULATION_OF_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 554 | 411 | 25 | ADORA2A,ADTRP,ARG2,BMP2,CEBPB,DUSP10,ETS1,FERMT3,GCNT2,ICAM1,IDO1,IL1B,IL6,IRF1,JAG1,MAD1L1,NCK1,NFKBIZ,NLRP3,RIPK2,SNAI2,SOCS1,VEGFA,XBP1,ZC3H12A |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 554 | 847 | 36 | ADORA2A,ADTRP,ARG2,BMP2,CDH13,CEBPB,CLDN12,DUSP10,ETS1,FERMT3,GCNT2,ICAM1,IDO1,IL1B,IL6,IRF1,ITGA2B,JAG1,KRT18,MAD1L1,NCK1,NFKBIZ,NLRP3,PCDHGA8,PEAR1,PLEK,RIPK2,ROBO3,SERPINB8,SNAI2,SOCS1,TNIP1,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1673 | 53 | ACVR2B,ASB1,BHLHE40,BHLHE41,BMP2,CBX4,CDKN1B,CEBPB,CFLAR,CIART,CIRBP,CPEB2,CPEB4,CSF2,EIF4EBP3,ELF3,ETS2,GATAD2B,HCLS1,HDAC9,HIVEP1,HMGA2,IKZF1,IL6,INHBA,IRF1,KLF3,LIN37,MLX,MSC,NCK1,NFKB2,NFX1,NOTO,NR3C1,ORMDL1,PER1,PLEK,PPARG,PRDM1,PTPRK,RBM4,RELB,SMAD2,SNAI2,SP100,TBX6,TEN1,TGIF1,TXNIP,VEGFA,ZC3H12A,ZFP36L1 |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 554 | 810 | 35 | ACVR2B,ADTRP,ANXA2P2,ANXA3,ARHGEF15,BTG1,C3AR1,CDH13,CFLAR,CXCL10,ETS1,FGF2,HDAC9,HMGA2,IL1A,IL1B,IL6,JAG1,MYDGF,PPARG,PRDM1,PTGS2,QKI,SH2D2A,SOD2,SP100,TBX6,TNFAIP2,TNFAIP3,TNFRSF12A,VEGFA,WARS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 643 | 31 | BIRC2,C3AR1,CDH13,CEBPB,CXCL10,DDX58,DHX58,ETS1,FGF2,IDO1,IFIH1,IKBKG,IL1B,IL6,INAVA,IRF1,MUC12,NFKBIA,NFKBIZ,NLRC4,NUPR1,PTGS2,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3,TSLP,VEGFA |
| GO_MYELOID_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 554 | 420 | 25 | ANXA2P2,CEBPB,CSF2,CSF3,CSF3R,DYRK3,ETS1,HCLS1,IKZF1,INHBA,ISG15,ITGA2B,JAG1,LTBR,NFE2L1,NFKBIA,PPARG,RELB,SH3PXD2A,SIGLEC15,SLC11A2,TFE3,TRIB1,VEGFA,ZFP36L1 |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 777 | 34 | ANXA2P2,ARG2,BIRC2,CFAP69,DDX58,DHX58,DUSP10,HMGA2,IFIH1,IFIT1,IKBKG,IL1B,INAVA,INHBA,IRF1,ISG15,MUC12,NFKBIA,NLRC4,PPARG,PPIB,PTX3,RELB,RIPK2,RSAD2,SOCS1,SPINK1,TIFA,TNFAIP3,TNIP1,TNIP3,TRIB1,TRIM38,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 261 | 20 | ANXA3,ARHGEF2,CFLAR,CSF3,DDX58,HCLS1,ICAM1,IKBKG,IL1B,IL6,JMY,NFKB2,NLRC4,NLRP3,PPARG,RBCK1,RIPK2,TRAF1,TRIM38,VEGFA |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 554 | 1864 | 56 | ARF1,ARHGEF2,ARID3A,AURKC,BAG6,BIRC2,BMP2,BTG1,C14orf39,CCNG2,CCPG1,CDH13,CDK20,CDK7,CDKN1B,CECR2,CHMP4A,CNPPD1,CSNK1E,DYNC1I2,DYRK3,GADD45B,HMGA2,IKZF1,IL1A,IL1B,INHBA,IRF1,JMY,KRT18,LIN37,MAD1L1,MAP3K20,MEI1,MOV10L1,NEK3,NFE2L1,NR3C1,NUPR1,PIM3,PLK5,PRDM7,PRKAG1,PTGS2,PTK6,PTPRK,SIAH1,STAG3L4,STAMBP,SYCE3,TNFAIP3,TOM1L1,TXNIP,UBE2E1,WTAP,ZFP36L1 |
| GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 554 | 155 | 16 | ARHGEF2,BMPR1B,CFLAR,CSF2,ICAM1,IL1A,IL1B,INHBA,ITPRIP,LTBR,RBCK1,SNAI2,SP100,TNFAIP3,TNFRSF12A,TRAF1 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 831 | 35 | ANXA2P2,ATP6V0D2,BAG6,CCDC22,CHMP4A,CIRBP,COMMD1,CSNK1E,DRAM1,DRAM2,DVL1,ERLEC1,IKBKG,IL1B,IL6,LRIG2,MFSD8,NFE2L1,NUB1,NUPR1,PRKAG1,RAB5A,RIPK2,RNF144B,RNF185,SH3D19,TNFAIP3,TNPO1,TOMM7,TRIB1,UBE2J1,WDR41,XBP1,ZC3H12A,ZFP36L1 |
| GO_RESPONSE_TO_DRUG | 0.0e+00 | 0.0e+00 | 554 | 1061 | 40 | ADORA2A,ARHGEF2,BIRC2,CATSPER3,CDKN1B,CFLAR,CSAG2,CSF3,DDIT4,DRD5,ETS1,GNA15,HDAC9,HMGA2,ICAM1,IL1B,IL6,INAVA,INHBA,JAG1,KCNMA1,KYNU,LCN2,MFSD10,NFKBIA,NFKBIE,NPAS2,NR3C1,PPARG,PTGS2,RIPK2,SCN11A,SLC22A1,SLC38A5,SLC7A2,SRP54,TGIF1,TNFAIP3,TXNIP,ZC3H12A |
| GO_IMMUNE_EFFECTOR_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1267 | 44 | AMPD3,ANXA3,ARPC2,BIRC2,BRI3,C17orf99,C3AR1,C5AR2,CXCL1,CXCL10,DDIT4,DDX58,DHX58,DUSP10,FLG2,ICAM1,IFIH1,IFIT1,IFIT2,IL13RA2,IL1B,IL6,IRF1,ISG15,JAG1,LCN2,NCK1,NFKBIZ,NLRP3,PDXK,PLAUR,PRAM1,PRDX6,PTX3,RELB,RIPK2,RSAD2,S100P,SERPINB10,TNFAIP3,TRIM38,UNC13D,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 514 | 27 | BIRC2,CEBPB,DDX58,DHX58,ETS1,IDO1,IFIH1,IKBKG,IL1B,IL6,INAVA,IRF1,MUC12,NFKBIA,NFKBIZ,NLRC4,NPAS2,NUPR1,PTGS2,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3,TSLP |
| GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 0.0e+00 | 0.0e+00 | 554 | 273 | 20 | BIRC2,CCDC22,CFLAR,IKBKG,IL1A,IL1B,INAVA,LTBR,NFKB2,NFKBIA,PER1,RBCK1,RELB,RIPK2,TIFA,TNFAIP3,TNIP1,TNIP3,TRIM38,ZC3H12A |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 987 | 38 | ANXA2P2,ATP6V0D2,BAG6,CCDC22,CDKN1B,CHMP4A,CIRBP,COMMD1,CSNK1E,DDIT4,DRAM1,DRAM2,DVL1,ERLEC1,IKBKG,IL1B,IL6,LRIG2,MFSD8,NFE2L1,NUB1,NUPR1,PRKAG1,RAB5A,RIPK2,RNF144B,RNF185,SH3D19,STX5,TNFAIP3,TNPO1,TOMM7,TRIB1,UBE2J1,WDR41,XBP1,ZC3H12A,ZFP36L1 |
| GO_CATION_TRANSPORT | 0.0e+00 | 0.0e+00 | 554 | 1180 | 42 | ADORA2A,ANXA2P2,ARF1,ATP5MGL,ATP6V0D2,BHLHA15,C15orf48,CATSPER3,CDKN1B,CNKSR3,COMMD1,COX7A2L,CSF2,CXCL10,FGF2,GRM6,GSTO1,ICAM1,JSRP1,KCNH6,KCNMA1,KCNQ3,LCN2,NFE2L1,NFKBIE,PER1,PTGS2,SCN11A,SLC10A7,SLC11A2,SLC15A3,SLC22A1,SLC25A37,SLC30A7,SLC33A1,SLC38A1,SLC38A5,SLC7A2,SLC9A4,SLC9A8,SPINK1,TRPM6 |
| GO_BLOOD_VESSEL_MORPHOGENESIS | 0.0e+00 | 0.0e+00 | 554 | 686 | 31 | ADTRP,ANXA2P2,ANXA3,BTG1,C3AR1,CDH13,CXCL10,ETS1,FGF2,HDAC9,HMGA2,IL1A,IL1B,IL6,JAG1,MYDGF,PPARG,PRDM1,PTGS2,QKI,SH2D2A,SP100,TBX6,TNFAIP2,TNFAIP3,TNFRSF12A,VEGFA,WARS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 554 | 1930 | 56 | ADPRH,ANXA2P2,ARF1,ARHGEF2,BAG6,BBC3,BRAF,CHMP4A,COG3,COMMD1,COPZ1,CSNK1E,DUSP16,DVL1,ERLEC1,FERMT2,FNTA,HCLS1,HM13,IFT43,IL1B,KIF1A,KRT18,LRIG2,MON1B,NFKBIA,PDIA2,PECR,PRAM1,PTGS2,PTPRK,RAB5A,RPL41,RPS17,SEC23B,SEC61G,SP100,SRP54,STX5,SYNE1,TBC1D10A,TIMM17B,TMED10,TMED7,TMEFF1,TNFAIP2,TNFAIP3,TNPO1,TOM1L1,TOMM7,TSPAN10,TXNIP,UBE2J1,VPS37C,ZC3H12A,ZFP36L1 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 1454 | 47 | ACVR2B,ADTRP,ARHGEF2,ATP6V0D2,BAMBI,BMP2,BMPR1B,CDK7,CEBPB,CFLAR,CPEB2,CPEB4,DDIT4,DRD5,ESRP1,FERMT2,FGF2,FNTA,GCNT2,GNA15,HDAC9,HIVEP1,ICAM1,IL1B,INHBA,KIF16B,KLF3,NCK1,NGF,NLRP3,NR3C1,PER1,PPARG,PRLR,PTGS2,PTPN12,PTPRK,RIPK2,SLC33A1,SMAD2,SNAI2,SOCS1,SRARP,STAT5A,VEPH1,XBP1,ZFP36L1 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 0.0e+00 | 0.0e+00 | 554 | 973 | 37 | ADORA2A,ADTRP,ANXA3,BIRC2,BMP2,CATSPER3,CDK7,CDKN1B,CEBPB,CFLAR,CXCL10,DDIT4,DDX58,DRD5,ETS1,GNA15,ICAM1,IFIH1,IFIT1,IL1B,IL6,INHBA,KYNU,NDUFS4,NFE2L1,NFKBIA,NR3C1,PER1,PPARG,PTGS2,RIPK2,SMAD2,SNAI2,SRARP,TXNIP,ZC3H12A,ZFP36L1 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 554 | 1741 | 52 | ADPRH,ANXA2P2,ARF1,ARHGEF2,BET1,BET1L,CCDC22,CHMP4A,CNIH4,COG3,COPZ1,DUSP16,DYNC1I2,ERLEC1,HCLS1,HM13,HYOU1,IFT43,IL13RA2,IL1B,KIF16B,KIF1A,LMAN2,MIA2,MON1B,NFKBIA,OSBP,PECR,PRKAG1,PTGS2,RAB5A,RBM4,RPL41,RPS17,SEC23B,SEC61G,SP100,SRP54,STX5,TBC1D10A,TIMM17B,TMED10,TMED7,TMEM115,TNPO1,TOM1L1,TOMM7,TXNIP,UBE2J1,UNC13D,VPS37C,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 554 | 1026 | 38 | BBC3,BIRC2,BMP2,BRAF,C5AR2,CCDC22,CDH13,CFLAR,COPS8,CSF3,DHX58,FGF2,GADD45B,GCNT2,GSTO1,HCLS1,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,LTBR,MAP3K20,MYDGF,NCK1,NGF,NUPR1,RBCK1,RIPK2,RNF13,S1PR2,SIAH1,STYXL1,TIFA,TRIM38,VEGFA,ZC3H12A |
| GO_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 0.0e+00 | 0.0e+00 | 554 | 84 | 12 | ATF6,BAG6,ERLEC1,FICD,HYOU1,MANF,NCK1,NFE2L1,NUPR1,RNF185,UBE2J1,XBP1 |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 554 | 362 | 22 | BAG6,BBC3,BCL2L13,CCDC22,CFLAR,CSNK1E,DVL1,IL1B,NGF,NLRC4,NLRP3,NUB1,NUPR1,PPARG,RIPK2,RNF144B,RNF185,SH3D19,TBC1D10A,TNIP1,TRIB1,ZC3H12A |
| GO_GOLGI_VESICLE_TRANSPORT | 0.0e+00 | 0.0e+00 | 554 | 367 | 22 | ARF1,BET1,BET1L,CCDC22,CNIH4,COG3,COMMD1,COPZ1,DYNC1I2,GOLGA5,HYOU1,KIF16B,KRT18,LMAN2,MIA2,SEC23B,SLC10A7,STX5,TMED10,TMED7,TMEM115,USE1 |
| GO_MODIFICATION_DEPENDENT_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 642 | 29 | ATE1,BAG6,BIRC2,CCDC22,COMMD1,CRBN,CSNK1E,DNAJC10,DVL1,ERLEC1,FBXL13,FBXO8,ISG15,NUB1,RBCK1,RNF13,RNF144B,RNF148,RNF185,SIAH1,SPSB1,TNFAIP3,TOM1L1,TRIB1,TRIM38,UBE2E1,UBE2J1,VPS37C,XBP1 |
| GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 554 | 522 | 26 | ARG2,BIRC2,DDX58,DHX58,DUSP10,IFIH1,IFIT1,IKBKG,IL1B,INAVA,IRF1,MUC12,NFKBIA,NLRC4,PPARG,RELB,RIPK2,RSAD2,SOCS1,TIFA,TNFAIP3,TNIP1,TNIP3,TRIB1,TRIM38,ZC3H12A |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 554 | 1782 | 52 | ALOX5AP,ANXA2P2,ARF1,ARHGEF2,ARPC2,BET1,BIRC2,CATIP,CDK7,CDKN1B,CHMP4A,COPS8,COX7A2L,CRBN,CSF2,CSF3,DNAAF1,EML2,FERMT2,FERMT3,HCLS1,HRK,ICAM1,IKZF1,JMY,KCTD7,LCN2,LMO4,LRRC49,MMP1,NBR1,NCK1,NDUFS4,NLRC4,NLRP3,NPHS1,NUPR1,PLEK,PRLR,SLC22A1,SMAD2,SOD2,SRP54,STX5,TIFA,TMED10,TRAF1,TRPM6,TTC17,VEGFA,WARS1,ZC3H12A |
| GO_DEFENSE_RESPONSE_TO_VIRUS | 0.0e+00 | 0.0e+00 | 554 | 244 | 18 | BIRC2,CXCL10,DDIT4,DDX58,DHX58,IFIH1,IFIT1,IFIT2,IL1B,IL6,IRF1,ISG15,NLRP3,RSAD2,TNFAIP3,TRIM38,UNC13D,ZC3H12A |
| GO_LYMPHOCYTE_ACTIVATION | 0.0e+00 | 0.0e+00 | 554 | 736 | 31 | ADORA2A,ARG2,BAG6,BTN3A1,C17orf99,CEBPB,DUSP10,ELF4,HDAC9,ICAM1,IDO1,IKZF1,IL1B,IL6,INHBA,IRF1,MAD1L1,NCK1,NFKBIZ,NLRP3,PRDM1,PRLR,RELB,RIPK2,RSAD2,SOCS1,TNFAIP3,UNC13D,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 554 | 1625 | 49 | ADORA2A,ARF1,ARHGEF2,BHLHE40,BHLHE41,BMP2,BMPR1B,CEBPB,CFLAR,CSNK1E,DDIT4,DNER,DUSP10,DVL1,ESRP1,HCLS1,HDAC9,IL1B,IL6,INHBA,JAG1,LAMC2,LMO4,LRIG2,LRP12,MANF,MFSD8,NCK1,NEK3,NFE2L1,NGF,NOTO,PARP6,PHACTR1,PLK5,PPARG,PRDM1,PTK6,PTPRK,RND1,ROBO3,SIAH1,SLC11A2,STYXL1,TBX6,TMEFF1,TNFRSF12A,VEGFA,XBP1 |
| GO_LEUKOCYTE_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 554 | 343 | 21 | ADORA2A,ADTRP,ARG2,CEBPB,DUSP10,ETS1,FERMT3,ICAM1,IDO1,IL1B,IL6,IRF1,MAD1L1,NCK1,NFKBIZ,NLRP3,RIPK2,SOCS1,TNIP1,XBP1,ZC3H12A |
| GO_REGULATION_OF_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 554 | 695 | 30 | ADORA2A,ADTRP,ARG2,ARPC2,BMP2,CDH13,CEBPB,DUSP10,ETS1,FERMT3,GCNT2,ICAM1,IDO1,IL1B,IL6,IRF1,JAG1,MAD1L1,NCK1,NFKBIZ,NLRP3,RIPK2,RND1,SNAI2,SOCS1,TFE3,UNC13D,VEGFA,XBP1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 1318 | 43 | ACVR2B,ADTRP,ANXA2P2,ARG2,ARHGEF15,ARHGEF2,ASB1,BMP2,C5AR2,CDKN1B,CXCL10,DDX58,DHX58,DUSP10,FGF2,HDAC9,IDO1,IFIH1,IL1B,IL6,INHBA,IRF1,ISG15,JAG1,KCNMA1,LRIG2,NBR1,NFKBIA,NLRP3,PLAUR,PPARG,PTGS2,RELB,S1PR2,SNAI2,SOCS1,SP100,TBX6,TFE3,TNFAIP3,TRIB1,ZC3H12A,ZFP36L1 |
| GO_ION_TRANSPORT | 0.0e+00 | 0.0e+00 | 554 | 1692 | 50 | ADORA2A,ANXA2P2,ARF1,ATP5MGL,ATP6V0D2,BHLHA15,C15orf48,CATSPER3,CDKN1B,CEBPB,CNKSR3,COMMD1,COX7A2L,CRBN,CSF2,CXCL10,FGF2,GRM6,GSTO1,ICAM1,IL1B,JSRP1,KCNH6,KCNMA1,KCNQ3,LCN2,MFSD10,NFE2L1,NFKBIE,PER1,PPARG,PTGS2,SCN11A,SLC10A7,SLC11A2,SLC15A3,SLC22A1,SLC25A37,SLC30A7,SLC33A1,SLC35C2,SLC38A1,SLC38A5,SLC7A2,SLC9A4,SLC9A8,SLCO1B3,SPINK1,TRPM6,TSC22D3 |
| GO_FAT_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 554 | 221 | 17 | ALOXE3,BMP2,CEBPB,DUSP10,HMGA2,IL6,JAG1,LAMB3,METRNL,MEX3C,PPARG,PTGS2,SNAI2,SOCS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_INFLAMMATORY_RESPONSE | 0.0e+00 | 0.0e+00 | 554 | 387 | 22 | ADORA2A,BIRC2,CEBPB,DUSP10,ETS1,IDO1,IL1B,IL6,METRNL,NFE2L1,NFKBIA,NFKBIZ,NLRP3,NUPR1,PER1,PPARG,PTGS2,SLC7A2,TNFAIP3,TNIP1,TSLP,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 554 | 542 | 26 | ARHGEF2,CCDC22,CNKSR3,DDIT4,DHX58,DUSP10,DUSP16,DUSP8,DYRK3,GSTO1,HYOU1,IL1B,NLRP3,PER1,PLAUR,PLEK,PTGS2,SNAI2,SOD2,SPINK1,STAMBP,TNFAIP3,TNIP1,TNIP3,XBP1,ZC3H12A |
| GO_REGULATION_OF_VASCULATURE_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 554 | 425 | 23 | ANXA3,BTG1,C3AR1,CFLAR,CXCL10,ETS1,FGF2,HDAC9,HMGA2,IL1A,IL1B,IL6,MYDGF,PPARG,PTGS2,SOD2,SP100,TNFAIP3,TNFRSF12A,VEGFA,WARS1,XBP1,ZC3H12A |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 554 | 1545 | 47 | ADORA2A,ARF1,ARPC2,BMPR1B,CATIP,CDH13,CFLAR,CSNK1E,DNAAF1,DVL1,DYNC1I2,GORAB,HCLS1,ICAM1,IFT43,IL6,IQCG,LAMC2,LCN2,LRIG2,LRP12,LRRC49,MANF,NCK1,NEK3,NGF,NOTO,OCRL,PARP6,PHACTR1,PLEK,PLK5,PTK6,PTPDC1,PTPRK,RAB5A,ROBO3,S1PR2,SIAH1,SLC11A2,STYXL1,TBX6,TMEFF1,TNFRSF12A,TNPO1,TTC17,VEGFA |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 0.0e+00 | 554 | 1287 | 42 | ADAP1,ADAP2,ADORA2A,ADPRH,ARHGEF15,BBC3,BCL2L13,BIRC2,BMP2,CFLAR,CPEB2,DNAJB11,DNAJC10,DYNC1I2,FGF2,FICD,FNTA,GNA15,HDAC9,ICAM1,IFIT1,NGF,NLRC4,NLRP3,OCRL,PHACTR1,PLAUR,PLEK,PPARG,PPP4R1L,PTGS2,PTX3,RIPK2,SEC23B,SERPINB10,SERPINB8,SPINK1,STYXL1,TBC1D10A,TFPI2,TNFAIP8,VEGFA |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 0.0e+00 | 554 | 1604 | 48 | ANXA2P2,ARF1,ATP5MGL,ATP6V0D2,BHLHA15,BRAF,C15orf48,CATSPER3,CNKSR3,COMMD1,COX7A2L,CRBN,CXCL10,ERLEC1,FGF2,GSTO1,IL1B,JSRP1,KCNH6,KCNMA1,KCNQ3,MFSD10,MFSD8,RNF185,SCN11A,SEC61G,SLC10A7,SLC11A2,SLC14A1,SLC15A3,SLC22A1,SLC25A37,SLC30A7,SLC33A1,SLC35C2,SLC35F6,SLC38A1,SLC38A5,SLC50A1,SLC7A2,SLC9A4,SLC9A8,SLCO1B3,SRP54,TIMM17B,TOMM7,TRPM6,TSC22D3 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 554 | 587 | 27 | ADORA2A,CDKN1B,CNKSR3,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,GADD45B,IL1B,INHBA,ITPRIP,NCK1,NUPR1,PER1,PHACTR1,PLEK,PTK6,SOCS1,SPINK1,STYXL1,TNFAIP3,TNIP1,TRIB1,WARS1,ZC3H12A |
| GO_T_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 554 | 468 | 24 | ADORA2A,ARG2,BTN3A1,CEBPB,DUSP10,ELF4,ICAM1,IDO1,IL1B,IL6,IRF1,MAD1L1,NCK1,NFKBIZ,NLRP3,PRDM1,PRLR,RELB,RIPK2,RSAD2,SOCS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 554 | 469 | 24 | ADORA2A,CDKN1B,CNKSR3,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,GADD45B,IL1B,INHBA,ITPRIP,NCK1,NUPR1,PER1,PTK6,SOCS1,SPINK1,TNFAIP3,TNIP1,TRIB1,WARS1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 0.0e+00 | 554 | 763 | 31 | ADORA2A,ARG2,BMP2,BMPR1B,BTG1,CDH13,CDKN1B,CEBPB,COPS8,CXCL1,DUSP10,ETS1,IDO1,IL1A,IL1B,IL6,INHBA,IRF1,MAD1L1,NGF,NUPR1,PPARG,PTGS2,PTPRK,SMAD2,SNAI2,SOD2,TMEM115,TNFAIP3,TRIB1,WARS1 |
| GO_REPRODUCTION | 0.0e+00 | 1.0e-07 | 554 | 1457 | 45 | ADCY10,ASB1,AURKC,BAG6,BIRC2,BMPR1B,BTG1,C14orf39,CATSPER3,CDKN1B,CEBPB,CFAP69,CSF2,DEDD,DRD5,ETS1,ICAM1,IDO1,IL1A,IL1B,INHBA,IQCG,MEI1,MOV10L1,NUPR1,PHLDA2,PLA2G4C,PPARG,PRDM1,PRDM7,PRKAG1,PRLR,PTGS2,PTX3,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,TCF23,UBE2J1,VEGFA,ZFP36L1,ZNF449 |
| GO_REGULATION_OF_HEMOPOIESIS | 0.0e+00 | 1.0e-07 | 554 | 477 | 24 | CEBPB,CSF2,CSF3,CSF3R,DUSP10,ETS1,HCLS1,INHBA,IRF1,ISG15,ITGA2B,JAG1,NFKBIA,NFKBIZ,NLRP3,PRDM1,RIPK2,SIGLEC15,SOCS1,TFE3,TRIB1,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 554 | 1470 | 45 | ACVR2B,BHLHE40,BHLHE41,BMP2,CBX4,CDKN1B,CEBPB,CIART,CIRBP,CSF2,DDIT4,ELF3,ETS2,GATAD2B,HCLS1,HDAC9,HIVEP1,HMGA2,IKZF1,IRF1,KLF3,LIN37,MLX,MSC,NCK1,NFKB2,NFX1,NOTO,NR3C1,NUPR1,PER1,PPARG,PRDM1,PTPRK,RELB,RNF169,SMAD2,SNAI2,SP100,TBX6,TEN1,TGIF1,TXNIP,VEGFA,ZC3H12A |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 1.0e-07 | 554 | 1365 | 43 | ADORA2A,ARF1,ARHGEF2,BMP2,BMPR1B,CEBPB,CFLAR,CSNK1E,DDIT4,DVL1,ESRP1,HCLS1,HDAC9,IL6,INHBA,JAG1,LAMC2,LMO4,LRIG2,LRP12,MANF,MFSD8,NCK1,NEK3,NFE2L1,NGF,NOTO,PARP6,PHACTR1,PLK5,PRDM1,PTK6,PTPRK,RND1,ROBO3,SIAH1,SLC11A2,STYXL1,TBX6,TMEFF1,TNFRSF12A,VEGFA,XBP1 |
| GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 0.0e+00 | 1.0e-07 | 554 | 518 | 25 | BMP2,BRAF,CCNG2,CDK7,CDKN1B,CNPPD1,CXCL10,DUSP10,DUSP16,DUSP8,FGF2,GADD45B,HMGA2,IKBKG,IL1B,INAVA,MAP3K20,NGF,PARP6,PRKAG1,RIPK2,S1PR2,TNFAIP3,TRIB1,VEGFA |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 1.0e-07 | 554 | 410 | 22 | ADORA2A,ADTRP,ANXA2P2,ARG2,C5AR2,CDKN1B,DHX58,DUSP10,DVL1,ETS1,FGF2,LRIG2,METRNL,NLRP3,NUCB2,PLAUR,PPARG,SNAI2,TNFAIP3,TRIB1,TRIM38,ZC3H12A |
| GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 554 | 63 | 10 | BIRC2,DDX58,DHX58,IFIH1,IKBKG,INAVA,NFKBIA,RIPK2,TIFA,TNFAIP3 |
| GO_REGULATION_OF_CELL_ACTIVATION | 0.0e+00 | 1.0e-07 | 554 | 619 | 27 | ADORA2A,ARG2,CEBPB,DUSP10,IDO1,IL13RA2,IL1B,IL6,INHBA,IRF1,LMO4,MAD1L1,NCK1,NFKBIZ,NLRP3,PLEK,PRAM1,PRDM1,RIPK2,SLC7A2,SOCS1,TNFAIP3,TSLP,UNC13D,XBP1,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_BINDING | 0.0e+00 | 1.0e-07 | 554 | 381 | 21 | ANXA2P2,BAMBI,BMP2,CCPG1,CRBN,CSF3,CSNK1E,DVL1,EDF1,HMGA2,IFIT1,IFIT2,LARP6,NFKBIA,NGF,PHLDA2,PLAUR,PPARG,RIPK2,SMAD2,SP100 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 2.0e-07 | 554 | 895 | 33 | ARPC2,BAG6,BIRC2,BTN3A1,C17orf99,C3AR1,C5AR2,DDX58,DHX58,IDO1,IFIH1,IKBKG,IL1B,IL6,INAVA,IRF1,MUC12,NCK1,NFKBIA,NFKBIZ,NLRC4,NLRP3,PRAM1,RBCK1,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3,XBP1,ZC3H12A |
| GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 0.0e+00 | 2.0e-07 | 554 | 132 | 13 | BMP2,CEBPB,DUSP10,IL6,JAG1,METRNL,MEX3C,PPARG,PTGS2,SNAI2,XBP1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 2.0e-07 | 554 | 860 | 32 | ACVR2B,BHLHE40,BHLHE41,BMP2,CBX4,CEBPB,ETS2,GATAD2B,HCLS1,HDAC9,HIVEP1,HMGA2,KLF3,LIN37,MLX,MSC,NCK1,NFKB2,NFX1,NOTO,NR3C1,PER1,PPARG,PRDM1,RELB,SMAD2,SNAI2,SP100,TBX6,TGIF1,TXNIP,VEGFA |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 2.0e-07 | 554 | 1258 | 40 | ARHGEF2,AURKC,BAG6,BRAF,CBX4,CLK4,CNKSR3,CSF2,CSF3,CSNK1E,DDIT4,DYRK3,DYRK4,HCLS1,HDAC9,HMGA2,ICAM1,IFIH1,IL1B,IL6,KMT5B,NCK1,OSTC,PER1,PPIB,PRDM7,PRLR,PTGS2,PTK6,RIPK2,RNF113A,S1PR2,SNAI2,SOCS1,SPINK1,ST6GAL1,SUPT3H,TSLP,UBE2J1,VEGFA |
| GO_REGULATION_OF_MAPK_CASCADE | 0.0e+00 | 2.0e-07 | 554 | 769 | 30 | BMP2,BRAF,C5AR2,CFLAR,CNKSR3,DUSP10,DUSP16,DUSP8,FGF2,GADD45B,GCNT2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,LTBR,MAP3K20,MYDGF,NBR1,NGF,PER1,RIPK2,S1PR2,TNIP1,TRIB1,VEGFA,ZC3H12A |
| GO_CYTOKINE_SECRETION | 0.0e+00 | 2.0e-07 | 554 | 252 | 17 | ARG2,BTN3A1,C5AR2,DDX58,HDAC9,IFIH1,IL1A,IL1B,ISG15,NLRC4,NLRP3,RIPK2,SOCS1,TNFAIP3,TSLP,XBP1,ZC3H12A |
| GO_ALPHA_BETA_T_CELL_ACTIVATION | 0.0e+00 | 3.0e-07 | 554 | 137 | 13 | ADORA2A,ARG2,ELF4,IL6,IRF1,NFKBIZ,NLRP3,PRDM1,RELB,RIPK2,RSAD2,SOCS1,ZC3H12A |
| GO_PEPTIDE_SECRETION | 0.0e+00 | 3.0e-07 | 554 | 641 | 27 | ACVR2B,ADORA2A,ADTRP,ARF1,ARG2,BTN3A1,C5AR2,DDX58,HDAC9,IFIH1,IL1A,IL1B,IL6,ISG15,MIA2,NLRC4,NLRP3,PIM3,PLEK,RIPK2,RSAD2,SMAD2,SOCS1,TNFAIP3,TSLP,XBP1,ZC3H12A |
| GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 554 | 478 | 23 | ATE1,BAG6,BIRC2,COMMD1,CRBN,CSNK1E,DNAJC10,DVL1,ERLEC1,FBXL13,HM13,NFE2L1,NUB1,NUPR1,RBCK1,RNF144B,RNF185,SIAH1,SPSB1,TRIB1,TRIM38,UBE2E1,UBE2J1 |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 4.0e-07 | 554 | 1235 | 39 | ARHGEF2,BHLHE40,BIRC2,BMP2,CDKN1B,CFLAR,CIRBP,CPEB2,CPEB4,CXCL10,DDIT4,ETS1,FNTA,GRM6,HMGA2,HYOU1,ICAM1,IL1A,IL1B,IRF1,KCNMA1,LTBR,MAP3K20,METRNL,NFE2L1,NFKBIA,PER1,PPARG,PTGS2,PTPRK,RBM4,RELB,SLC11A2,SNAI2,TSC22D3,TXNIP,VEGFA,XRRA1,ZFP36L1 |
| GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 0.0e+00 | 4.0e-07 | 554 | 297 | 18 | BMP2,DUSP10,GADD45B,IKBKG,IL1A,IL1B,INAVA,LTBR,MAP3K20,NBR1,NPHS1,PER1,RIPK2,RNF13,TRIB1,VEGFA,ZC3H12A,ZFP36L1 |
| GO_EPITHELIUM_DEVELOPMENT | 0.0e+00 | 4.0e-07 | 554 | 1296 | 40 | ACVR2B,ANXA2P2,ARG2,BMP2,BTG1,CDKN1B,CEBPB,CXCL10,DNAAF1,DUSP10,DVL1,EDF1,ELF3,ESRP1,FGF2,FLG2,GORAB,ICAM1,IL1B,INHBA,JAG1,KRT17,KRT18,LMO4,NOTO,NPHS1,PPARG,PRDM1,PTK6,S1PR2,SLC9A4,SMAD2,SNAI2,SPRR2D,TBX6,TXNIP,VEGFA,XBP1,YIPF6,ZFP36L1 |
| GO_INTERLEUKIN_6_PRODUCTION | 0.0e+00 | 4.0e-07 | 554 | 171 | 14 | ARHGEF2,C5AR2,CEBPB,DDX58,IFIH1,IL1A,IL1B,IL6,INAVA,RIPK2,TNFAIP3,TSLP,XBP1,ZC3H12A |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 4.0e-07 | 554 | 940 | 33 | ANXA2P2,ARF1,CFLAR,CHMP4A,DDX58,DHX58,DYNC1I2,HMGA2,ICAM1,IFIH1,IFIT1,IKBKG,ISG15,KRT18,LTBR,MMP1,MON1B,NFKBIA,NFX1,NLRC4,PPIB,PTX3,RAB5A,RBCK1,RPL41,RPS17,RSAD2,SP100,TNIP1,TNPO1,TRIM38,VPS37C,ZC3H12A |
| GO_WOUND_HEALING | 0.0e+00 | 4.0e-07 | 554 | 572 | 25 | ADORA2A,ADTRP,ANXA2P2,CDKN1B,CFLAR,DRD5,DUSP10,ETS1,FERMT3,FGF2,GNA15,IL1A,IL6,IRF1,ITGA2B,PEAR1,PLAUR,PLEK,PTPN12,RAB5A,SMAD2,TFPI2,TNFAIP3,TNFRSF12A,XBP1 |
| GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | 0.0e+00 | 4.0e-07 | 554 | 232 | 16 | ANXA3,BTG1,C3AR1,CFLAR,ETS1,FGF2,HDAC9,HMGA2,IL1A,IL1B,MYDGF,PTGS2,SOD2,VEGFA,XBP1,ZC3H12A |
| GO_MYELOID_CELL_HOMEOSTASIS | 0.0e+00 | 6.0e-07 | 554 | 147 | 13 | AMPD3,DYRK3,ETS1,HCLS1,IKZF1,IL6,INHBA,ISG15,NFE2L1,RPS17,SLC11A2,VEGFA,ZFP36L1 |
| GO_ERYTHROCYTE_HOMEOSTASIS | 0.0e+00 | 6.0e-07 | 554 | 122 | 12 | AMPD3,DYRK3,ETS1,HCLS1,IKZF1,INHBA,ISG15,NFE2L1,RPS17,SLC11A2,VEGFA,ZFP36L1 |
| GO_ENDOPLASMIC_RETICULUM_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT | 0.0e+00 | 6.0e-07 | 554 | 207 | 15 | ARF1,BET1,BET1L,CNIH4,COG3,COPZ1,DYNC1I2,HYOU1,LMAN2,MIA2,SEC23B,STX5,TMED10,TMED7,TMEM115 |
| GO_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | 0.0e+00 | 7.0e-07 | 554 | 674 | 27 | ARPC2,BAG6,BIRC2,BTN3A1,C3AR1,C5AR2,DDX58,DHX58,IFIH1,IKBKG,INAVA,IRF1,MS4A2,MUC12,NCK1,NFKBIA,NFKBIZ,PRAM1,RBCK1,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3,ZC3H12A |
| GO_ACTIVATION_OF_IMMUNE_RESPONSE | 0.0e+00 | 7.0e-07 | 554 | 720 | 28 | ARPC2,BAG6,BIRC2,BTN3A1,C3AR1,C5AR2,DDX58,DHX58,IFIH1,IKBKG,IL1B,INAVA,IRF1,MUC12,NCK1,NFKBIA,NFKBIZ,NLRC4,PRAM1,RBCK1,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3,ZC3H12A |
| GO_MYELOID_LEUKOCYTE_DIFFERENTIATION | 0.0e+00 | 7.0e-07 | 554 | 208 | 15 | ANXA2P2,CEBPB,CSF2,CSF3,HCLS1,INHBA,LTBR,PPARG,RELB,SH3PXD2A,SIGLEC15,TFE3,TRIB1,VEGFA,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 0.0e+00 | 7.0e-07 | 554 | 960 | 33 | ANXA2P2,BAMBI,BMP2,C5AR2,CCPG1,CDH13,CDKN1B,CFLAR,CSF2,CSF3,CXCL10,ETS1,FGF2,GCNT2,HCLS1,HMGA2,IL1B,IL6,LAMC2,MEF2D,MYDGF,NCK1,NDUFS4,PTGS2,RIPK2,S1PR2,SLC35F6,STAMBP,STAT5A,TNFAIP3,TSLP,VEGFA,XBP1 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 7.0e-07 | 554 | 912 | 32 | ASB1,BIRC2,CBX4,CCDC22,COMMD1,CRBN,DCAF10,FBXL13,IFIH1,INAVA,ISG15,MAGEC2,NFE2L1,NFX1,NUB1,RBCK1,RIPK2,RNF113A,RNF13,RNF144B,RNF148,RNF169,RNF185,SIAH1,SOCS1,SPSB1,TNFAIP3,TRIM38,TRIML2,UBE2E1,UBE2F,UBE2J1 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 0.0e+00 | 7.0e-07 | 554 | 1163 | 37 | AMTN,ANXA3,ARPC2,BAMBI,BMP2,BTG1,C3AR1,CFLAR,CXCL10,DVL1,ETS1,FERMT2,FGF2,HCLS1,HDAC9,HMGA2,ICAM1,IL1A,IL1B,IL6,JAG1,MYDGF,NGF,PARP6,PPARG,PTGS2,RND1,SH3D19,SNAI2,SP100,TNFAIP3,TNFRSF12A,UNC13D,VEGFA,WARS1,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 8.0e-07 | 554 | 1220 | 38 | ANXA2P2,ARF1,ARHGEF15,ARPC2,BBC3,CDKN1B,CFLAR,CSF2,CSF3,DVL1,HCLS1,HRK,ICAM1,IL1A,IL1B,IL6,JMY,LCN2,LINGO2,MMP1,NCK1,NGF,NPHS1,PARP6,PLAUR,PLEK,PLK5,PPARG,PRDM7,PTK6,SNAI2,STYXL1,TNFRSF12A,TOMM7,TSPAN1,UNC13D,VEGFA,WARS1 |
| GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 0.0e+00 | 9.0e-07 | 554 | 278 | 17 | ALOXE3,BIRC2,CDK7,DDX58,DHX58,IFIH1,IKBKG,INAVA,NFKBIA,NR3C1,PER1,PPARG,RIPK2,SNAI2,SRARP,TIFA,TNFAIP3 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 9.0e-07 | 554 | 1280 | 39 | ACVR2B,BHLHE40,BHLHE41,BMP2,CBX4,CDKN1B,CEBPB,CIART,CSF2,ELF3,ETS2,GATAD2B,HCLS1,HDAC9,HIVEP1,HMGA2,IKZF1,IRF1,KLF3,LIN37,MLX,MSC,NCK1,NFKB2,NFX1,NOTO,NR3C1,PER1,PPARG,PRDM1,PTPRK,RELB,SMAD2,SNAI2,SP100,TBX6,TGIF1,TXNIP,VEGFA |
| GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 9.0e-07 | 554 | 388 | 20 | ANXA2P2,BAG6,CCDC22,CDKN1B,COMMD1,CSNK1E,DVL1,ERLEC1,IL1B,LRIG2,NFE2L1,NUB1,NUPR1,RNF144B,RNF185,SH3D19,STX5,TNFAIP3,TRIB1,UBE2J1 |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 9.0e-07 | 554 | 687 | 27 | ADORA2A,ADTRP,ANXA2P2,CDKN1B,CFLAR,DRD5,DUSP10,ETS1,FERMT3,FGF2,GNA15,IL1A,IL6,IRF1,ITGA2B,LRIG2,PEAR1,PLAUR,PLEK,PTPN12,RAB5A,SMAD2,TFPI2,TNFAIP3,TNFRSF12A,XBP1,ZFP36L1 |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 9.0e-07 | 554 | 974 | 33 | BMP2,BRAF,C5AR2,CFLAR,CNKSR3,CSF2,DUSP10,DUSP16,DUSP8,FGF2,GADD45B,GCNT2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,INHBA,LTBR,MAP3K20,MYDGF,NBR1,NGF,NPHS1,PER1,RIPK2,S1PR2,TNIP1,TRIB1,VEGFA,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 1.2e-06 | 554 | 984 | 33 | ADORA2A,ANXA2P2,ARF1,BBC3,BRAF,CEBPB,CNKSR3,CXCL10,DDX58,GRM6,GSTO1,HCLS1,IFIH1,IL1A,IL1B,IL6,INHBA,KCTD7,LMAN2,NFKBIA,NLRP3,PPARG,PTGS2,PTX3,RAB5A,RIPK2,TOMM7,TSLP,TSPAN1,UNC13D,VEGFA,XBP1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 1.3e-06 | 554 | 286 | 17 | ADORA2A,CDKN1B,DUSP10,DUSP16,DUSP8,DVL1,GADD45B,IL1B,ITPRIP,NCK1,PPARG,PTK6,SOCS1,TEN1,TNFAIP3,TRIB1,WARS1 |
| GO_POSITIVE_REGULATION_OF_HEMOPOIESIS | 0.0e+00 | 1.3e-06 | 554 | 188 | 14 | CSF3,DUSP10,ETS1,HCLS1,INHBA,ISG15,JAG1,NFKBIZ,NLRP3,RIPK2,SOCS1,TRIB1,XBP1,ZFP36L1 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 1.4e-06 | 554 | 289 | 17 | ARHGEF2,BAG6,BBC3,CEBPB,DDIT4,DNAJC10,HYOU1,JMY,NCK1,NUPR1,PLAUR,PTGS2,SIAH1,SNAI2,SOD2,STYXL1,XBP1 |
| GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS | 0.0e+00 | 1.5e-06 | 554 | 483 | 22 | ACVR2B,ALOXE3,AMPD3,CEBPB,DRAM2,FLG2,GATM,GCNT2,IL1A,IL1B,IL6,INAVA,LCN2,METRNL,MEX3C,PRLR,PTGS2,SIGLEC15,SLC11A2,TFE3,TNFAIP3,VEGFA |
| GO_RESPONSE_TO_PEPTIDE | 0.0e+00 | 1.5e-06 | 554 | 525 | 23 | ARHGEF2,ATP6V0D2,BTG1,CDKN1B,CFLAR,CPEB2,HDAC9,ICAM1,IL1B,INAVA,JAG1,KLF3,NCK1,NFKBIA,PPARG,PRLR,PTGS2,RIPK2,SOCS1,STAT5A,TNFAIP3,XBP1,ZFP36L1 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 1.5e-06 | 554 | 1151 | 36 | ADPRH,ARF1,ARHGEF2,CHMP4A,COG3,COPZ1,DUSP16,ERLEC1,HCLS1,HM13,IFT43,IL1B,KIF1A,MON1B,NFKBIA,PECR,PTGS2,RAB5A,RPL41,RPS17,SEC23B,SEC61G,SP100,SRP54,STX5,TBC1D10A,TIMM17B,TMED10,TMED7,TNPO1,TOM1L1,TOMM7,TXNIP,UBE2J1,VPS37C,ZC3H12A |
| GO_CHEMICAL_HOMEOSTASIS | 0.0e+00 | 1.6e-06 | 554 | 1207 | 37 | ADORA2A,ALOXE3,ANXA2P2,ARF1,ATP6V0D2,BHLHA15,C3AR1,C5AR2,CCDC22,COMMD1,CXCL10,DRD5,FGF2,FLG2,GNA15,GSTO1,HDAC9,ICAM1,IFIT1,JSRP1,KCNMA1,KCTD7,LCN2,NFE2L1,ORMDL1,PIM3,PNPLA1,PPARG,SLC10A7,SLC11A2,SLC25A37,SLC30A7,SLC9A4,SLC9A8,SOD2,VEGFA,XBP1 |
| GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 0.0e+00 | 1.6e-06 | 554 | 64 | 9 | BMP2,CEBPB,METRNL,PPARG,PTGS2,SNAI2,XBP1,ZC3H12A,ZFP36L1 |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 1.6e-06 | 554 | 1051 | 34 | ACVR2B,ANGPTL1,ARPC2,ATP6V0D2,BAMBI,BMP2,BMPR1B,CDH13,DDIT4,ESRP1,FERMT2,FGF2,FNTA,GCNT2,HIVEP1,IL1B,INHBA,KIF16B,LRIG2,NCK1,NGF,PLAUR,PRLR,PTK6,PTPN12,PTPRK,SH2D2A,SLC33A1,SMAD2,SOCS1,STAT5A,TXNIP,VEGFA,VEPH1 |
| GO_RHYTHMIC_PROCESS | 0.0e+00 | 1.7e-06 | 554 | 293 | 17 | ADORA2A,BHLHE40,BHLHE41,BMPR1B,CIART,CSF2,CSNK1E,ETS1,GPR176,INHBA,NFKB2,NPAS2,PER1,PPARG,PTX3,RBM4,RELB |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 1.8e-06 | 554 | 620 | 25 | ADORA2A,CDKN1B,CNKSR3,DDIT4,DNAJC10,DUSP10,DUSP16,DUSP8,DVL1,GADD45B,IL1B,ISG15,ITPRIP,NCK1,PER1,PHACTR1,PTK6,SOCS1,SPINK1,STYXL1,TNFAIP3,TNIP1,TRIB1,WARS1,ZC3H12A |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 1.8e-06 | 554 | 955 | 32 | ARF1,ARHGEF2,ARPC2,BHLHE40,BHLHE41,BMP2,CFLAR,CSNK1E,DUSP10,DVL1,ESRP1,HCLS1,HDAC9,IL1B,IL6,JAG1,LRIG2,NCK1,NGF,PARP6,PHACTR1,PLK5,PPARG,PTK6,S1PR2,SIGLEC15,STYXL1,TBX6,TNFRSF12A,TRIB1,UNC13D,VEGFA |
| GO_METAL_ION_TRANSPORT | 0.0e+00 | 1.9e-06 | 554 | 906 | 31 | ADORA2A,ANXA2P2,ARF1,ATP6V0D2,BHLHA15,CATSPER3,CDKN1B,CNKSR3,COMMD1,CXCL10,FGF2,GRM6,GSTO1,ICAM1,JSRP1,KCNH6,KCNMA1,KCNQ3,LCN2,PER1,PTGS2,SCN11A,SLC10A7,SLC11A2,SLC25A37,SLC30A7,SLC38A1,SLC9A4,SLC9A8,SPINK1,TRPM6 |
| GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 0.0e+00 | 1.9e-06 | 554 | 227 | 15 | ANXA2P2,ARG2,DHX58,DUSP10,HMGA2,IFIT1,ISG15,PPARG,PTX3,RSAD2,TNFAIP3,TNIP1,TRIB1,TRIM38,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 1.9e-06 | 554 | 534 | 23 | ADTRP,ARG2,C5AR2,COMMD1,CRBN,ERLEC1,GSTO1,HDAC9,ICAM1,IL13RA2,IL1B,INHBA,MCTP1,NLRP3,PIM3,PTGS2,RSAD2,SLC35F6,SP100,SPINK1,TNFAIP3,UBE2J1,ZC3H12A |
| GO_REGULATION_OF_CELL_CYCLE | 1.0e-07 | 2.2e-06 | 554 | 1224 | 37 | ARID3A,AURKC,BIRC2,BMP2,BTG1,CCNG2,CCPG1,CDK20,CDK7,CDKN1B,CNPPD1,CSNK1E,DYNC1I2,DYRK3,GADD45B,HMGA2,IL1A,IL1B,INHBA,IRF1,JMY,LIN37,MAD1L1,MAP3K20,NFE2L1,NUPR1,PIM3,PLK5,PRDM7,PRKAG1,PTGS2,PTK6,PTPRK,TNFAIP3,TOM1L1,UBE2E1,ZFP36L1 |
| GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 1.0e-07 | 2.2e-06 | 554 | 455 | 21 | BIRC2,C17orf99,C3AR1,C5AR2,DDX58,DHX58,DUSP10,IFIT1,IL13RA2,IL1B,IL6,NFKBIZ,NLRP3,PRAM1,RIPK2,RSAD2,TNFAIP3,TRIM38,UNC13D,XBP1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 2.3e-06 | 554 | 231 | 15 | ARHGEF2,CFLAR,CSF2,HYOU1,ICAM1,IL1A,IL1B,ITPRIP,PLAUR,PTGS2,SLC35F6,SNAI2,SOD2,TNFAIP3,XBP1 |
| GO_RESPONSE_TO_MURAMYL_DIPEPTIDE | 1.0e-07 | 2.4e-06 | 554 | 20 | 6 | ARHGEF2,INAVA,JAG1,NFKBIA,RIPK2,TNFAIP3 |
| GO_NEGATIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 1.0e-07 | 2.8e-06 | 554 | 171 | 13 | BHLHE40,CCDC22,COMMD1,NFKBIA,NFKBIE,NLRP3,NUPR1,RBCK1,SP100,TBX6,TNFAIP3,TRIB1,ZC3H12A |
| GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 1.0e-07 | 2.8e-06 | 554 | 202 | 14 | BIRC2,DDX58,DHX58,IFIH1,IKBKG,INAVA,IRF1,NFKBIA,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3 |
| GO_RESPONSE_TO_GROWTH_FACTOR | 1.0e-07 | 3.0e-06 | 554 | 732 | 27 | ACVR2B,ANXA3,BAMBI,BMP2,BMPR1B,CFLAR,DDIT4,ESRP1,FERMT2,FGF2,FNTA,GCNT2,HIVEP1,IL1B,KIF16B,NGF,NR3C1,PLK5,PTPN12,PTPRK,SLC33A1,SMAD2,SNAI2,TGIF1,VEGFA,VEPH1,ZFP36L1 |
| GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 1.0e-07 | 3.4e-06 | 554 | 238 | 15 | ADORA2A,BBC3,BCL2L13,BIRC2,CFLAR,NGF,NLRC4,NLRP3,PLAUR,PPARG,PTGS2,RIPK2,TBC1D10A,TNFAIP8,VEGFA |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 1.0e-07 | 3.5e-06 | 554 | 468 | 21 | ARHGEF2,BIRC2,C3AR1,CEBPB,CSF2,DDX58,DHX58,IDO1,IFIH1,IL1A,IL1B,IL6,INAVA,IRF1,NFKB2,NLRP3,PTGS2,RIPK2,RSAD2,TSLP,XBP1 |
| GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 1.0e-07 | 3.9e-06 | 554 | 276 | 16 | CEBPB,DUSP10,HCLS1,INHBA,IRF1,NFKBIZ,NLRP3,PRDM1,RIPK2,SIGLEC15,SOCS1,TFE3,TRIB1,XBP1,ZC3H12A,ZFP36L1 |
| GO_P38MAPK_CASCADE | 1.0e-07 | 4.0e-06 | 554 | 52 | 8 | BMP2,DUSP10,GADD45B,IL1B,PER1,VEGFA,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 1.0e-07 | 4.0e-06 | 554 | 431 | 20 | BAG6,CCDC22,CDKN1B,CSNK1E,DVL1,IKBKG,IL1B,IL6,NUB1,NUPR1,RIPK2,RNF144B,RNF185,SH3D19,STX5,TNFAIP3,TOMM7,TRIB1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 1.0e-07 | 4.0e-06 | 554 | 604 | 24 | ANXA3,ARHGEF2,BMP2,C3AR1,CDH13,CFAP69,CXCL10,ETS1,FERMT3,FGF2,GCNT2,HDAC9,ICAM1,IL1B,IL6,ITGA2B,LAMC2,PTGS2,SNAI2,SOD2,STAT5A,VEGFA,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | 1.0e-07 | 4.2e-06 | 554 | 148 | 12 | ARHGEF2,CFLAR,ICAM1,IKBKG,IL1B,NFKB2,NLRC4,NLRP3,RBCK1,RIPK2,TRAF1,TRIM38 |
| GO_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 1.0e-07 | 4.1e-06 | 554 | 432 | 20 | ARF1,ARHGEF2,ARPC2,BIRC2,CDKN1B,CRBN,CSF2,CSF3,EML2,HCLS1,HRK,ICAM1,JMY,LMO4,MMP1,NCK1,NPHS1,PLEK,VEGFA,WARS1 |
| GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS | 1.0e-07 | 4.5e-06 | 554 | 244 | 15 | AMPD3,DYRK3,ETS1,HCLS1,IKZF1,IL6,INHBA,ISG15,NFE2L1,RPS17,SLC11A2,TNFAIP3,TSC22D3,VEGFA,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 4.8e-06 | 554 | 180 | 13 | ADORA2A,BBC3,BMPR1B,HRK,INHBA,LTBR,NCK1,NUPR1,PLAUR,RBCK1,SIAH1,STYXL1,TNFRSF12A |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 1.0e-07 | 4.7e-06 | 554 | 1267 | 37 | ANXA2P2,ARF1,ARHGEF15,ARHGEF2,ARPC2,BBC3,CDKN1B,CHMP4A,CSF2,CSF3,EML2,HCLS1,HRK,ICAM1,IL1A,IL1B,JMY,MAD1L1,NCK1,NFE2L1,NOTO,NPHS1,NUPR1,PLAUR,PLEK,PRDM7,RAB5A,RND1,SIGLEC15,SLC35F6,SNAI2,STX5,STYXL1,TEN1,TOM1L1,TOMM7,VEGFA |
| GO_REGULATION_OF_T_CELL_ACTIVATION | 1.0e-07 | 4.8e-06 | 554 | 318 | 17 | ADORA2A,ARG2,CEBPB,DUSP10,IDO1,IL1B,IL6,IRF1,MAD1L1,NCK1,NFKBIZ,NLRP3,PRDM1,RIPK2,SOCS1,XBP1,ZC3H12A |
| GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 1.0e-07 | 5.2e-06 | 554 | 614 | 24 | ADTRP,BMP2,CDK7,CDKN1B,CEBPB,CFLAR,DDIT4,DDX58,DRD5,GNA15,ICAM1,IFIH1,IFIT1,IL1B,INHBA,NFE2L1,NR3C1,PER1,PPARG,PTGS2,SNAI2,SRARP,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 1.0e-07 | 5.2e-06 | 554 | 481 | 21 | ADORA2A,ADTRP,ARG2,C5AR2,CEBPB,DHX58,DUSP10,IDO1,IL13RA2,INHBA,IRF1,MAD1L1,NFKBIA,PPARG,SOCS1,TNFAIP3,TRIB1,TRIM38,TSC22D3,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | 2.0e-07 | 5.4e-06 | 554 | 98 | 10 | ARHGEF2,DDX58,IFIH1,IL1A,IL1B,IL6,INAVA,RIPK2,TSLP,XBP1 |
| GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | 2.0e-07 | 5.7e-06 | 554 | 322 | 17 | BIRC2,DDX58,DHX58,IFIH1,IKBKG,INAVA,IRF1,MUC12,NFKBIA,NLRC4,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3 |
| GO_CELLULAR_HOMEOSTASIS | 2.0e-07 | 6.2e-06 | 554 | 963 | 31 | ANXA2P2,ARF1,ATP6V0D2,C3AR1,C5AR2,CCDC22,CXCL10,DNAJC10,DRD5,FGF2,GNA15,GSTO1,ICAM1,IL6,JSRP1,KCNMA1,KCTD7,LCN2,NFE2L1,ORMDL1,PDIA2,PDIA5,PIM3,PRDX6,SLC10A7,SLC11A2,SLC30A7,SLC9A4,SLC9A8,TXNDC9,XBP1 |
| GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | 2.0e-07 | 6.0e-06 | 554 | 184 | 13 | ADORA2A,ADTRP,ARG2,BMP2,CEBPB,IDO1,IRF1,JAG1,MAD1L1,SNAI2,SOCS1,VEGFA,ZC3H12A |
| GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 2.0e-07 | 6.0e-06 | 554 | 286 | 16 | ARG2,BIRC2,CFLAR,DDIT4,DRD5,ICAM1,IL1B,INAVA,NDUFS4,PRDX6,PTGS2,PTX3,SH3PXD2A,SLC7A2,SOD2,ZC3H12A |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 2.0e-07 | 6.3e-06 | 554 | 1016 | 32 | ADCY10,AURKC,BAG6,BMPR1B,BTG1,C14orf39,CATSPER3,CFAP69,DEDD,DRD5,ETS1,IDO1,IL1B,INHBA,IQCG,MEI1,MOV10L1,PLA2G4C,PRDM1,PRKAG1,PRLR,PTGS2,PTX3,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,TCF23,UBE2J1,ZNF449 |
| GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 2.0e-07 | 6.4e-06 | 554 | 252 | 15 | ANXA2P2,BAG6,CCDC22,COMMD1,CSNK1E,DVL1,ERLEC1,NFE2L1,NUB1,NUPR1,RNF144B,RNF185,TNFAIP3,TRIB1,UBE2J1 |
| GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 2.0e-07 | 6.4e-06 | 554 | 252 | 15 | CEBPB,CSF2,CSF3,CSF3R,ETS1,HCLS1,INHBA,ISG15,ITGA2B,JAG1,NFKBIA,SIGLEC15,TFE3,TRIB1,ZFP36L1 |
| GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 2.0e-07 | 6.7e-06 | 554 | 767 | 27 | ADORA2A,ADTRP,ARF1,ARG2,BBC3,C5AR2,DDX58,ERLEC1,HCLS1,HDAC9,IFIH1,IL1A,IL1B,IL6,NLRP3,PIM3,PTGS2,RIPK2,RSAD2,SOCS1,SP100,TNFAIP3,TOMM7,TSLP,UBE2J1,XBP1,ZC3H12A |
| GO_ALPHA_BETA_T_CELL_DIFFERENTIATION | 2.0e-07 | 6.9e-06 | 554 | 101 | 10 | IL6,IRF1,NFKBIZ,NLRP3,PRDM1,RELB,RIPK2,RSAD2,SOCS1,ZC3H12A |
| GO_MUSCLE_STRUCTURE_DEVELOPMENT | 2.0e-07 | 7.0e-06 | 554 | 673 | 25 | BHLHA15,BHLHE41,BMP2,BTG1,CFLAR,CXCL10,DNER,FGF2,FOXN2,HDAC9,JAG1,KMT5B,MEF2D,MSC,NPHS1,NUPR1,PDLIM4,QKI,RBM4,SOD2,SYNE1,TCF23,VEGFA,XBP1,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 2.0e-07 | 6.8e-06 | 554 | 366 | 18 | BAG6,CCDC22,CSNK1E,DVL1,IKBKG,IL1B,IL6,NUB1,NUPR1,RIPK2,RNF144B,RNF185,SH3D19,TNFAIP3,TOMM7,TRIB1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 2.0e-07 | 6.8e-06 | 554 | 219 | 14 | BAG6,CCDC22,CDKN1B,CSNK1E,DVL1,IL1B,NUB1,NUPR1,RNF144B,RNF185,SH3D19,STX5,TNFAIP3,TRIB1 |
| GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 2.0e-07 | 7.9e-06 | 554 | 189 | 13 | BIRC2,DDX58,IFIH1,IKBKG,IL6,PPARG,RBCK1,RIPK2,RNF113A,SOCS1,TNFAIP3,TRAF1,TSLP |
| GO_NEGATIVE_REGULATION_OF_CELL_ADHESION | 2.0e-07 | 8.1e-06 | 554 | 294 | 16 | ADORA2A,ADTRP,ARG2,BMP2,CDH13,CEBPB,GCNT2,IDO1,IRF1,JAG1,MAD1L1,RND1,SNAI2,SOCS1,VEGFA,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 2.0e-07 | 7.9e-06 | 554 | 540 | 22 | BIRC2,CFAP69,DDX58,DHX58,IFIH1,IFIT1,IKBKG,INAVA,INHBA,IRF1,MUC12,NFKBIA,NLRC4,PPIB,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3,TRIM38 |
| GO_REGULATION_OF_SECRETION | 2.0e-07 | 7.9e-06 | 554 | 824 | 28 | ADORA2A,ADTRP,ARF1,ARG2,C5AR2,DDX58,DVL1,HDAC9,IFIH1,IL13RA2,IL1A,IL1B,IL6,INHBA,MCTP1,NLRP3,NPHS1,PIM3,PRAM1,RAB5A,RIPK2,RSAD2,SOCS1,TNFAIP3,TSLP,UNC13D,XBP1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 2.0e-07 | 8.3e-06 | 554 | 258 | 15 | ADORA2A,CDKN1B,DUSP10,DUSP16,DUSP8,DVL1,GADD45B,IL1B,ITPRIP,NCK1,PTK6,SOCS1,TNFAIP3,TRIB1,WARS1 |
| GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 3.0e-07 | 8.8e-06 | 554 | 334 | 17 | ACVR2B,BMP2,BRAF,COPS8,FGF2,GADD45B,IKBKG,IL1B,INAVA,MAP3K20,NGF,PRLR,RIPK2,S1PR2,SOCS1,TOM1L1,VEGFA |
| GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 3.0e-07 | 1.0e-05 | 554 | 162 | 12 | ATF6,BAG6,BHLHA15,DNAJB11,FICD,HYOU1,MYDGF,NCK1,PARP6,PDIA5,RNF185,XBP1 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL | 3.0e-07 | 1.0e-05 | 554 | 299 | 16 | BIRC2,COPS8,DDX58,IFIH1,IKBKG,NFKBIA,NLRP3,OTUD1,OTUD6A,SMAD2,STAMBP,SUPT3H,TNFAIP3,TNIP1,TNIP3,ZC3H12A |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 3.0e-07 | 1.1e-05 | 554 | 942 | 30 | ARF1,ARHGEF15,ARHGEF2,ARPC2,BIRC2,CDKN1B,CHMP4A,CRBN,CSF2,CSF3,EML2,HCLS1,HRK,ICAM1,IL1B,JMY,LINGO2,LMO4,MMP1,NCK1,NOTO,NPHS1,NUPR1,ORMDL1,PLEK,RAB5A,SNAI2,STYXL1,VEGFA,WARS1 |
| GO_ION_TRANSMEMBRANE_TRANSPORT | 4.0e-07 | 1.3e-05 | 554 | 1160 | 34 | ANXA2P2,ARF1,ATP5MGL,ATP6V0D2,BHLHA15,C15orf48,CATSPER3,CNKSR3,COMMD1,COX7A2L,CRBN,CXCL10,FGF2,GSTO1,JSRP1,KCNH6,KCNMA1,KCNQ3,MFSD10,SCN11A,SLC11A2,SLC15A3,SLC22A1,SLC25A37,SLC30A7,SLC33A1,SLC35C2,SLC38A1,SLC38A5,SLC7A2,SLC9A4,SLC9A8,TRPM6,TSC22D3 |
| GO_GAMETE_GENERATION | 4.0e-07 | 1.3e-05 | 554 | 698 | 25 | ADCY10,AURKC,BAG6,BMPR1B,BTG1,C14orf39,CATSPER3,CFAP69,DEDD,INHBA,IQCG,MEI1,MOV10L1,PRDM1,PRKAG1,PTGS2,PTX3,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,UBE2J1,ZNF449 |
| GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 4.0e-07 | 1.3e-05 | 554 | 166 | 12 | ARHGEF2,BBC3,HYOU1,NCK1,NUPR1,PLAUR,PTGS2,SIAH1,SNAI2,SOD2,STYXL1,XBP1 |
| GO_ACUTE_INFLAMMATORY_RESPONSE | 4.0e-07 | 1.3e-05 | 554 | 109 | 10 | CEBPB,ICAM1,IL1A,IL1B,IL6,NLRP3,NUPR1,PPARG,PTGS2,TREM1 |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 5.0e-07 | 1.5e-05 | 554 | 562 | 22 | ARF1,ARHGEF2,ARPC2,BMP2,CFLAR,CSNK1E,DVL1,HCLS1,IL1B,IL6,NCK1,NGF,PARP6,PLK5,PPARG,PTK6,S1PR2,STYXL1,TNFRSF12A,TRIB1,UNC13D,VEGFA |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 5.0e-07 | 1.5e-05 | 554 | 853 | 28 | ADCY10,AURKC,BAG6,BMPR1B,BTG1,C14orf39,CATSPER3,CFAP69,DEDD,DRD5,ETS1,INHBA,IQCG,MEI1,MOV10L1,PRDM1,PRKAG1,PTGS2,PTX3,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,TCF23,UBE2J1,ZNF449 |
| GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 5.0e-07 | 1.5e-05 | 554 | 201 | 13 | ATF6,BAG6,BHLHA15,DNAJB11,FICD,HYOU1,MANF,MYDGF,NCK1,PARP6,PDIA5,RNF185,XBP1 |
| GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 5.0e-07 | 1.6e-05 | 554 | 86 | 9 | ARHGEF2,BMPR1B,CFLAR,DEDD,ICAM1,ITPRIP,NGF,SP100,TNFAIP3 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 5.0e-07 | 1.7e-05 | 554 | 709 | 25 | ARHGEF2,ATP6V0D2,CEBPB,CFLAR,CPEB2,CPEB4,DDX58,DRD5,GNA15,HDAC9,ICAM1,IFIH1,IFIT1,IL1B,KLF3,NCK1,NLRP3,PPARG,PRLR,PTGS2,RIPK2,SOCS1,STAT5A,XBP1,ZFP36L1 |
| GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 6.0e-07 | 1.7e-05 | 554 | 710 | 25 | AMPD3,ANXA3,BRI3,C17orf99,C3AR1,CXCL1,FLG2,ICAM1,IL13RA2,IL6,LCN2,NFKBIZ,NLRP3,PDXK,PLAUR,PRAM1,PRDX6,PTX3,RELB,RIPK2,S100P,SERPINB10,UNC13D,XBP1,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 6.0e-07 | 1.7e-05 | 554 | 204 | 13 | ADTRP,ARG2,C5AR2,ERLEC1,HDAC9,IL1B,NLRP3,PIM3,RSAD2,SP100,TNFAIP3,UBE2J1,ZC3H12A |
| GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | 6.0e-07 | 1.7e-05 | 554 | 313 | 16 | ARHGEF2,BIRC2,ICAM1,IKBKG,KRT18,LCN2,LTBR,NFKBIA,NUB1,PTGS2,RBCK1,TNFAIP3,TNFRSF12A,TRAF1,ZC3H12A,ZFP36L1 |
| GO_LYMPHOCYTE_DIFFERENTIATION | 6.0e-07 | 1.8e-05 | 554 | 354 | 17 | C17orf99,DUSP10,HDAC9,IKZF1,IL6,INHBA,IRF1,NFKBIZ,NLRP3,PRDM1,RELB,RIPK2,RSAD2,SOCS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 7.0e-07 | 2.1e-05 | 554 | 243 | 14 | ARF1,ARPC2,CDKN1B,CSF2,CSF3,HRK,ICAM1,JMY,MMP1,NCK1,NPHS1,PLEK,VEGFA,WARS1 |
| GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 7.0e-07 | 2.1e-05 | 554 | 243 | 14 | BMP2,DUSP10,GADD45B,IL1A,IL1B,INAVA,LTBR,MAP3K20,NBR1,PER1,RIPK2,RNF13,VEGFA,ZC3H12A |
| GO_EMBRYO_DEVELOPMENT | 7.0e-07 | 2.2e-05 | 554 | 1029 | 31 | ACVR2B,APBA3,BAG6,BMP2,CEBPB,CSF2,DNAAF1,DVL1,ELF3,ETS2,FGF2,GORAB,HM13,HMGA2,HOXB9,INHBA,KIF16B,LAMB3,LMO4,MAP3K20,MYO15A,NOTO,OCRL,PHLDA2,PRDM1,SH3PXD2A,SMAD2,SP8,TBX6,VEGFA,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 7.0e-07 | 2.2e-05 | 554 | 577 | 22 | ACVR2B,BMP2,BRAF,CDKN1B,COPS8,FGF2,GADD45B,HMGA2,IKBKG,IL1B,INAVA,LMO4,MAP3K20,NGF,PARP6,PRKAG1,PRLR,RIPK2,S1PR2,SOCS1,TOM1L1,VEGFA |
| GO_EPITHELIAL_CELL_DIFFERENTIATION | 8.0e-07 | 2.4e-05 | 554 | 774 | 26 | ACVR2B,ANXA2P2,BMP2,BTG1,CDKN1B,CEBPB,EDF1,ELF3,ESRP1,ICAM1,IL1B,JAG1,KRT17,KRT18,NPHS1,PPARG,PRDM1,PTK6,S1PR2,SLC9A4,SPRR2D,TXNIP,VEGFA,XBP1,YIPF6,ZFP36L1 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 8.0e-07 | 2.4e-05 | 554 | 928 | 29 | ARF1,ARHGEF15,ARHGEF2,BHLHE40,BHLHE41,BMP2,CFLAR,CSNK1E,DUSP10,DVL1,ESRP1,GORAB,HCLS1,IL1B,IL6,JAG1,LINGO2,LRIG2,NCK1,NGF,PARP6,PHACTR1,PLK5,PPARG,PTK6,STYXL1,TBX6,TNFRSF12A,VEGFA |
| GO_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 8.0e-07 | 2.5e-05 | 554 | 491 | 20 | ADORA2A,ARG2,CEBPB,DUSP10,IDO1,IL1B,IL6,INHBA,IRF1,MAD1L1,NCK1,NFKBIZ,NLRP3,PRDM1,RIPK2,SOCS1,TNFAIP3,XBP1,ZC3H12A,ZFP36L1 |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 8.0e-07 | 2.5e-05 | 554 | 879 | 28 | ANXA2P2,ARF1,ATP5MGL,ATP6V0D2,BHLHA15,C15orf48,CATSPER3,CNKSR3,COMMD1,COX7A2L,CXCL10,FGF2,GSTO1,JSRP1,KCNH6,KCNMA1,KCNQ3,SCN11A,SLC11A2,SLC15A3,SLC22A1,SLC25A37,SLC30A7,SLC33A1,SLC7A2,SLC9A4,SLC9A8,TRPM6 |
| GO_REGULATION_OF_PROTEIN_LOCALIZATION | 8.0e-07 | 2.5e-05 | 554 | 1037 | 31 | ADORA2A,ADTRP,ARF1,ARG2,BBC3,C5AR2,COMMD1,CSNK1E,DDX58,DVL1,ERLEC1,HCLS1,HDAC9,IFIH1,IL1A,IL1B,IL6,LRIG2,NLRP3,PIM3,PTGS2,RIPK2,RSAD2,SOCS1,SP100,TNFAIP3,TOMM7,TSLP,UBE2J1,XBP1,ZC3H12A |
| GO_MONOVALENT_INORGANIC_CATION_TRANSPORT | 8.0e-07 | 2.5e-05 | 554 | 537 | 21 | ARF1,ATP5MGL,ATP6V0D2,C15orf48,CATSPER3,CDKN1B,CNKSR3,COMMD1,COX7A2L,KCNH6,KCNMA1,KCNQ3,PER1,SCN11A,SLC10A7,SLC11A2,SLC15A3,SLC33A1,SLC38A1,SLC9A4,SLC9A8 |
| GO_RESPONSE_TO_TOXIC_SUBSTANCE | 9.0e-07 | 2.7e-05 | 554 | 539 | 21 | ABTB2,ADORA2A,ALOX5AP,BIRC2,CSF3,DRD5,ETS1,GSTO1,HDAC9,ICAM1,IL6,KCNMA1,LCN2,NUPR1,PRDX6,PTGS2,SOD2,TNFAIP3,TRPM6,TXNIP,ZC3H12A |
| GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 9.0e-07 | 2.7e-05 | 554 | 92 | 9 | ARG2,IL6,NFKBIZ,NLRP3,RELB,RIPK2,RSAD2,SOCS1,ZC3H12A |
| GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 9.0e-07 | 2.7e-05 | 554 | 92 | 9 | ADORA2A,ARG2,IRF1,NFKBIZ,NLRP3,PRDM1,RIPK2,SOCS1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | 1.0e-06 | 3.0e-05 | 554 | 150 | 11 | CEBPB,ETS1,IDO1,IL1B,IL6,NFKBIA,NFKBIZ,NUPR1,PTGS2,TNIP1,TSLP |
| GO_RESPONSE_TO_HORMONE | 1.0e-06 | 3.0e-05 | 554 | 994 | 30 | ADTRP,ANXA3,ATP6V0D2,BTG1,CATSPER3,CDK7,CDKN1B,CFLAR,CPEB2,DDIT4,ETS1,GNA15,HCLS1,HDAC9,ICAM1,IL1B,IL6,INHBA,NCK1,NR3C1,PER1,PPARG,PRLR,PTGS2,SOCS1,SRARP,STAT5A,TXNIP,XBP1,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_BINDING | 1.1e-06 | 3.1e-05 | 554 | 182 | 12 | ANXA2P2,BAMBI,BMP2,CRBN,CSF3,EDF1,HMGA2,LARP6,NGF,PLAUR,PPARG,RIPK2 |
| GO_REGULATION_OF_PEPTIDASE_ACTIVITY | 1.1e-06 | 3.1e-05 | 554 | 455 | 19 | ADORA2A,BBC3,BCL2L13,BIRC2,CFLAR,NGF,NLRC4,NLRP3,PLAUR,PPARG,PTGS2,RIPK2,SERPINB10,SERPINB8,SPINK1,TBC1D10A,TFPI2,TNFAIP8,VEGFA |
| GO_CYTOSKELETON_ORGANIZATION | 1.2e-06 | 3.5e-05 | 554 | 1335 | 36 | ARF1,ARHGEF15,ARHGEF2,ARPC2,AURKC,CATIP,CDKN1B,CECR2,CFLAR,CSF3,CXCL1,DNAAF1,DVL1,EML2,HCLS1,ICAM1,IQCG,JMY,KRT17,KRT18,LRRC49,MAP3K20,NCK1,NPHS1,NUAK2,PDLIM4,PHACTR1,PLEK,PSTPIP2,RND1,S1PR2,SH3D19,SIGLEC15,SYNE1,TNFAIP3,TTC17 |
| GO_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 1.2e-06 | 3.4e-05 | 554 | 122 | 10 | ATF6,BHLHA15,DNAJB11,FICD,HYOU1,MYDGF,NCK1,PARP6,PDIA5,XBP1 |
| GO_NEGATIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION | 1.2e-06 | 3.5e-05 | 554 | 18 | 5 | BHLHA15,BHLHE41,CFLAR,CXCL10,XBP1 |
| GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 1.2e-06 | 3.4e-05 | 554 | 184 | 12 | BIRC2,CCDC22,CFLAR,IKBKG,IL1A,IL1B,INAVA,LTBR,RBCK1,RIPK2,TIFA,TRIM38 |
| GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 1.2e-06 | 3.4e-05 | 554 | 548 | 21 | BMP2,BRAF,C5AR2,CFLAR,FGF2,GADD45B,GCNT2,ICAM1,IKBKG,IL1A,IL1B,IL6,INAVA,LTBR,MAP3K20,MYDGF,NGF,RIPK2,S1PR2,VEGFA,ZC3H12A |
| GO_CELL_DIVISION | 1.3e-06 | 3.6e-05 | 554 | 598 | 22 | ARF1,ARHGEF2,AURKC,CCNG2,CDK20,CDK7,CECR2,CHMP4A,DYRK3,FGF2,HMGA2,IL1A,IL1B,MAD1L1,NEK3,NR3C1,PLK5,STAMBP,SYCE3,TXNIP,VEGFA,ZNF449 |
| GO_EXOCYTOSIS | 1.3e-06 | 3.7e-05 | 554 | 900 | 28 | ADORA2A,AMPD3,ANXA3,ARF1,BRI3,C3AR1,CTSW,CXCL1,DVL1,FERMT3,FLG2,IL13RA2,ITGA2B,LCN2,MANF,PDXK,PLAUR,PLEK,PRAM1,PRDX6,PTX3,RAB5A,S100P,SERPINB10,TMED10,TNFAIP2,UNC13D,VEGFA |
| GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 1.3e-06 | 3.7e-05 | 554 | 50 | 7 | BAMBI,BMP2,GCNT2,IL1B,IL6,JAG1,SMAD2 |
| GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 1.3e-06 | 3.5e-05 | 554 | 185 | 12 | BAG6,COMMD1,CSNK1E,DVL1,ERLEC1,NFE2L1,NUB1,NUPR1,RNF144B,RNF185,TRIB1,UBE2J1 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 1.4e-06 | 3.8e-05 | 554 | 1117 | 32 | ADCY10,ALG12,AMPD3,ATP5MGL,B3GNT5,B3GNT6,BMP2,BMPR1B,CMPK2,COG3,DDIT4,FGF2,GCNT2,GLYCTK,GUK1,IL1B,KYNU,MUC12,NFE2L1,NUPR1,OSTC,PRKAG1,PTX3,RNF185,SLC10A7,SLC35C2,ST3GAL1,ST6GAL1,TMEM115,TNIP1,UBE2J1,UPP1 |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 1.4e-06 | 3.9e-05 | 554 | 650 | 23 | AMPD3,ANXA3,BRI3,C3AR1,CSF2,CXCL1,FLG2,IL13RA2,IL6,LCN2,LTBR,PDXK,PLAUR,PRAM1,PRDX6,PTX3,RELB,S100P,SERPINB10,SLC7A2,TSLP,UNC13D,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 1.4e-06 | 3.9e-05 | 554 | 463 | 19 | ADORA2A,BIRC2,CFLAR,CPEB2,FICD,HDAC9,IFIT1,NGF,PHACTR1,PLAUR,PTGS2,PTX3,SERPINB10,SERPINB8,SPINK1,STYXL1,TFPI2,TNFAIP8,VEGFA |
| GO_MAINTENANCE_OF_LOCATION | 1.5e-06 | 4.2e-05 | 554 | 338 | 16 | CCDC22,CXCL10,FGF2,GSTO1,IL1B,IL6,JSRP1,LCN2,NFKBIA,NFKBIE,PDIA2,PPARG,SLC30A7,SP100,SYNE1,ZC3H12A |
| GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 1.5e-06 | 4.2e-05 | 554 | 338 | 16 | BMP2,BRAF,DUSP10,DUSP16,DUSP8,FGF2,GADD45B,IKBKG,IL1B,INAVA,MAP3K20,NGF,RIPK2,S1PR2,TRIB1,VEGFA |
| GO_REGULATION_OF_PEPTIDE_SECRETION | 1.5e-06 | 4.2e-05 | 554 | 511 | 20 | ADORA2A,ADTRP,ARF1,ARG2,C5AR2,DDX58,HDAC9,IFIH1,IL1A,IL1B,IL6,NLRP3,PIM3,RIPK2,RSAD2,SOCS1,TNFAIP3,TSLP,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 1.6e-06 | 4.4e-05 | 554 | 655 | 23 | ACVR2B,BMP2,BRAF,CDKN1B,COPS8,FGF2,GADD45B,HMGA2,IKBKG,IL1B,INAVA,LMO4,MAGEC2,MAP3K20,NGF,PARP6,PRKAG1,PRLR,RIPK2,S1PR2,SOCS1,TOM1L1,VEGFA |
| GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | 1.7e-06 | 4.6e-05 | 554 | 74 | 8 | IL6,NFKBIZ,NLRP3,RELB,RIPK2,RSAD2,SOCS1,ZC3H12A |
| GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 1.7e-06 | 4.6e-05 | 554 | 74 | 8 | BIRC2,DDX58,DHX58,IFIT1,IL1B,TNFAIP3,TRIM38,ZC3H12A |
| GO_TYPE_I_INTERFERON_PRODUCTION | 1.9e-06 | 5.3e-05 | 554 | 129 | 10 | DDX58,DHX58,IFIH1,IRF1,ISG15,NFKB2,RELB,RIPK2,TNFAIP3,TRIM38 |
| GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 2.0e-06 | 5.3e-05 | 554 | 160 | 11 | C17orf99,DUSP10,IL1B,IL6,IRF1,NFKBIZ,NLRP3,RIPK2,RSAD2,TNFAIP3,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 2.2e-06 | 5.9e-05 | 554 | 307 | 15 | ARG2,ASB1,C5AR2,DDX58,DHX58,HDAC9,IDO1,IFIH1,IL6,INHBA,ISG15,NLRP3,RELB,TNFAIP3,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 2.2e-06 | 5.8e-05 | 554 | 767 | 25 | ADAP1,ADAP2,ADPRH,ARHGEF15,BBC3,BCL2L13,BMP2,CFLAR,DNAJB11,DNAJC10,DYNC1I2,FGF2,FNTA,GNA15,ICAM1,NGF,NLRC4,NLRP3,OCRL,PLEK,PPARG,RIPK2,SEC23B,TBC1D10A,VEGFA |
| GO_CELL_FATE_COMMITMENT | 2.5e-06 | 6.6e-05 | 554 | 271 | 14 | ARHGEF2,BMP2,CEBPB,ESRP1,ETS2,FGF2,IL6,JAG1,LMO4,NFE2L1,PPARG,PRDM1,SMAD2,TBX6 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 2.5e-06 | 6.6e-05 | 554 | 351 | 16 | ARHGEF2,CFLAR,CPEB2,ETS1,IL6,LCN2,NFE2L1,PPARG,PRDX6,PTGS2,PTPRK,RELB,SOD2,TNFAIP3,ZC3H12A,ZFP36L1 |
| GO_ENDOTHELIUM_DEVELOPMENT | 2.6e-06 | 6.7e-05 | 554 | 133 | 10 | ACVR2B,ANXA2P2,BTG1,CXCL10,EDF1,ICAM1,IL1B,JAG1,S1PR2,VEGFA |
| GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 2.6e-06 | 6.7e-05 | 554 | 104 | 9 | ARHGEF2,CFLAR,CSF2,ICAM1,IL1A,IL1B,ITPRIP,SNAI2,TNFAIP3 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 2.6e-06 | 6.7e-05 | 554 | 624 | 22 | ANXA2P2,ARF1,ARHGEF15,ARPC2,BBC3,CDKN1B,CSF2,CSF3,HCLS1,HRK,ICAM1,IL1A,IL1B,JMY,NCK1,NPHS1,PLAUR,PLEK,PRDM7,SNAI2,TOMM7,VEGFA |
| GO_EPITHELIAL_CELL_PROLIFERATION | 2.8e-06 | 7.4e-05 | 554 | 441 | 18 | BMP2,C5AR2,CDH13,CDKN1B,CEBPB,CFLAR,DUSP10,FGF2,MYDGF,NUPR1,PPARG,PTPRK,SNAI2,STAT5A,TNFAIP3,VEGFA,XBP1,ZFP36L1 |
| GO_GROWTH | 2.8e-06 | 7.3e-05 | 554 | 990 | 29 | ACVR2B,ANXA2P2,BMPR1B,BTG1,CDKN1B,CFLAR,DUSP10,DVL1,FGF2,HCLS1,HMGA2,INHBA,KRT17,LRP12,MEX3C,MUC12,NGF,PHLDA2,PPARG,PPIB,PTK6,PTPN12,PTX3,SMAD2,SOCS1,STAT5A,TNFRSF12A,VEGFA,ZFP36L1 |
| GO_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_SIGNALING_PATHWAY | 3.1e-06 | 8.1e-05 | 554 | 37 | 6 | BIRC2,IKBKG,INAVA,NFKBIA,RIPK2,TNFAIP3 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 3.1e-06 | 8.1e-05 | 554 | 400 | 17 | BIRC2,DDX58,DHX58,IFIH1,IKBKG,INAVA,IRF1,MUC12,NFKBIA,NLRC4,RELB,RIPK2,RSAD2,TIFA,TNFAIP3,TNIP1,TNIP3 |
| GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 3.2e-06 | 8.3e-05 | 554 | 401 | 17 | ARPC2,CDH13,DUSP10,ETS1,GCNT2,ICAM1,IL1B,IL6,NCK1,NFKBIZ,NLRP3,RIPK2,SOCS1,TFE3,UNC13D,VEGFA,XBP1 |
| GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS | 3.4e-06 | 8.8e-05 | 554 | 360 | 16 | ADORA2A,BAG6,BIRC2,CFLAR,ERLEC1,LRIG2,NGF,PLAUR,PTGS2,SERPINB10,SERPINB8,SPINK1,TFPI2,TNFAIP8,UBE2J1,VEGFA |
| GO_T_CELL_DIFFERENTIATION | 3.4e-06 | 8.7e-05 | 554 | 240 | 13 | DUSP10,IL6,IRF1,NFKBIZ,NLRP3,PRDM1,RELB,RIPK2,RSAD2,SOCS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_PEPTIDYL_SERINE_MODIFICATION | 3.5e-06 | 9.0e-05 | 554 | 319 | 15 | AURKC,BRAF,CNKSR3,CSF3,CSNK1E,DDIT4,DYRK3,DYRK4,HCLS1,HMGA2,IL6,NCK1,PTGS2,RIPK2,VEGFA |
| GO_HEART_DEVELOPMENT | 3.6e-06 | 9.2e-05 | 554 | 589 | 21 | ACVR2B,ADAP2,ANXA2P2,BMP2,CDKN1B,DNAAF1,DVL1,FGF2,HDAC9,JAG1,LMO4,MEF2D,NOTO,PDLIM4,PPARG,PRDM1,SMAD2,SNAI2,TBX6,VEGFA,ZFP36L1 |
| GO_NEURON_DEVELOPMENT | 3.6e-06 | 9.2e-05 | 554 | 1114 | 31 | ADORA2A,ARF1,BMPR1B,CFLAR,DVL1,HCLS1,IL6,LAMC2,LRIG2,LRP12,MANF,MFSD8,NCK1,NEK3,NGF,PARP6,PHACTR1,PLK5,PRDM1,PTK6,PTPRK,RND1,ROBO3,SIAH1,SLC11A2,STYXL1,TBX6,TMEFF1,TNFRSF12A,VEGFA,XBP1 |
| GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 3.6e-06 | 9.2e-05 | 554 | 58 | 7 | ARHGEF2,BMPR1B,CFLAR,ICAM1,ITPRIP,SP100,TNFAIP3 |
| GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION | 3.7e-06 | 9.3e-05 | 554 | 38 | 6 | BHLHA15,CPEB4,NUAK2,UPP1,XBP1,ZC3H12A |
| GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 3.7e-06 | 9.4e-05 | 554 | 171 | 11 | DUSP10,INHBA,IRF1,NFKBIZ,NLRP3,PRDM1,RIPK2,SOCS1,XBP1,ZC3H12A,ZFP36L1 |
| GO_CIRCADIAN_RHYTHM | 4.0e-06 | 1.0e-04 | 554 | 207 | 12 | ADORA2A,BHLHE40,BHLHE41,CIART,CSF2,CSNK1E,GPR176,NPAS2,PER1,PPARG,RBM4,RELB |
| GO_SEXUAL_REPRODUCTION | 4.0e-06 | 1.0e-04 | 554 | 847 | 26 | ADCY10,AURKC,BAG6,BMPR1B,BTG1,C14orf39,CATSPER3,CFAP69,DEDD,DRD5,INHBA,IQCG,MEI1,MOV10L1,PRDM1,PRKAG1,PTGS2,PTX3,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,UBE2J1,ZNF449 |
| GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | 4.1e-06 | 1.0e-04 | 554 | 140 | 10 | BRAF,CNKSR3,CSF3,DDIT4,HCLS1,IL6,NCK1,PTGS2,RIPK2,VEGFA |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 4.2e-06 | 1.1e-04 | 554 | 547 | 20 | ARF1,ARHGEF2,BMP2,CFLAR,CSNK1E,DVL1,GORAB,HCLS1,IL1B,IL6,LINGO2,NCK1,NGF,PARP6,PLK5,PPARG,PTK6,STYXL1,TNFRSF12A,VEGFA |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 4.6e-06 | 1.1e-04 | 554 | 1071 | 30 | ACVR2B,AMTN,ANXA2P2,BHLHE41,BMP2,BMPR1B,BRAF,CEBPB,CFLAR,CSF3R,DNAAF1,DVL1,ELF3,FGF2,INHBA,JAG1,LAMB3,LAMC2,MEF2D,MYO15A,NOTO,PHLDA2,PRDM1,SMAD2,SNAI2,TBX6,TMEFF1,TNFAIP3,VEGFA,XBP1 |
| GO_GLYCOPROTEIN_METABOLIC_PROCESS | 4.6e-06 | 1.1e-04 | 554 | 412 | 17 | ALG12,B3GNT5,B3GNT6,BMP2,BMPR1B,COG3,GCNT2,MUC12,OSTC,PTX3,RNF185,SLC35C2,ST3GAL1,ST6GAL1,TMEM115,TNIP1,UBE2J1 |
| GO_RESPONSE_TO_PEPTIDOGLYCAN | 4.6e-06 | 1.1e-04 | 554 | 11 | 4 | IL6,INAVA,NLRP3,RIPK2 |
| GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 4.7e-06 | 1.2e-04 | 554 | 750 | 24 | ARHGEF2,BHLHA15,BHLHE41,BMP2,CFLAR,CXCL10,DUSP10,IL1B,IL6,INHBA,IRF1,JAG1,LRIG2,NBR1,NFKBIA,PPARG,SNAI2,SOCS1,TBX6,TRIB1,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 4.7e-06 | 1.1e-04 | 554 | 175 | 11 | BMP2,GADD45B,IL1A,IL1B,INAVA,LTBR,MAP3K20,RIPK2,RNF13,VEGFA,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 4.9e-06 | 1.2e-04 | 554 | 143 | 10 | BAG6,CCDC22,CSNK1E,DVL1,NUB1,NUPR1,RNF144B,RNF185,TNFAIP3,TRIB1 |
| GO_REGULATION_OF_BODY_FLUID_LEVELS | 5.0e-06 | 1.2e-04 | 554 | 506 | 19 | ADORA2A,ADTRP,ALOXE3,ANXA2P2,FERMT3,FLG2,GNA15,IL6,IRF1,ITGA2B,PEAR1,PLAUR,PLEK,PRLR,RAB5A,STAT5A,TFPI2,VEGFA,XBP1 |
| GO_PEPTIDYL_TYROSINE_MODIFICATION | 5.2e-06 | 1.3e-04 | 554 | 372 | 16 | ARHGEF2,CLK4,CSF2,CSF3,DYRK3,DYRK4,HCLS1,ICAM1,IL6,PRLR,PTK6,RIPK2,SOCS1,SPINK1,TSLP,VEGFA |
| GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 5.4e-06 | 1.3e-04 | 554 | 373 | 16 | ADTRP,ANXA2P2,CFLAR,ELF3,ETS1,FGF2,ICAM1,IL6,ITGA2B,LAMB3,LAMC2,MMP1,NFKB2,NPHS1,PTX3,SH3PXD2A |
| GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 5.4e-06 | 1.3e-04 | 554 | 213 | 12 | C17orf99,DDX58,DHX58,IL13RA2,IL1B,IL6,NFKBIZ,NLRP3,RIPK2,RSAD2,UNC13D,XBP1 |
| GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ENDOPLASMIC_RETICULUM | 5.4e-06 | 1.3e-04 | 554 | 86 | 8 | BET1L,COG3,COPZ1,LMAN2,TMED10,TMED7,TMEM115,USE1 |
| GO_CIRCADIAN_REGULATION_OF_GENE_EXPRESSION | 5.7e-06 | 1.4e-04 | 554 | 62 | 7 | BHLHE40,BHLHE41,CIART,CSNK1E,NPAS2,PER1,RELB |
| GO_MALE_GAMETE_GENERATION | 6.3e-06 | 1.5e-04 | 554 | 562 | 20 | ADCY10,AURKC,BAG6,BTG1,C14orf39,CATSPER3,CFAP69,DEDD,IQCG,MEI1,MOV10L1,PRKAG1,QKI,SIAH1,SPATA24,SPINK1,SYCE3,SYNE1,UBE2J1,ZNF449 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 6.4e-06 | 1.5e-04 | 554 | 63 | 7 | BAG6,BBC3,CEBPB,DNAJC10,HYOU1,NCK1,XBP1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 6.8e-06 | 1.6e-04 | 554 | 337 | 15 | BMP2,BRAF,CDKN1B,FGF2,GADD45B,HMGA2,IKBKG,IL1B,INAVA,MAP3K20,NGF,PARP6,RIPK2,S1PR2,VEGFA |
| GO_REGULATION_OF_RESPONSE_TO_WOUNDING | 7.6e-06 | 1.8e-04 | 554 | 184 | 11 | ADTRP,ANXA2P2,CDKN1B,DUSP10,FGF2,LRIG2,PLAUR,PLEK,TNFAIP3,TNFRSF12A,XBP1 |
| GO_PEPTIDE_METABOLIC_PROCESS | 7.7e-06 | 1.8e-04 | 554 | 879 | 26 | CIRBP,CPEB2,CPEB4,EIF4EBP3,FTSJ1,GSAP,HM13,IL6,KRT17,LARP6,MRPS24,NCK1,NFE2L1,NGF,PER1,QKI,RBM3,RBM4,RPL41,RPS17,SEC11C,TMED10,TNIP1,WARS1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 7.8e-06 | 1.8e-04 | 554 | 43 | 6 | BHLHA15,BHLHE41,BMP2,CFLAR,CXCL10,XBP1 |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 8.0e-06 | 1.9e-04 | 554 | 671 | 22 | ADCY10,ALG12,AMPD3,ATP5MGL,B3GNT5,B3GNT6,BMPR1B,CMPK2,COG3,GCNT2,GUK1,IL1B,MUC12,OSTC,SLC10A7,SLC35C2,ST3GAL1,ST6GAL1,TMEM115,TNIP1,UBE2J1,UPP1 |
| GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 8.0e-06 | 1.9e-04 | 554 | 151 | 10 | ADORA2A,ARG2,CEBPB,IDO1,INHBA,IRF1,MAD1L1,SOCS1,TNFAIP3,ZC3H12A |
| GO_REGULATION_OF_WOUND_HEALING | 8.5e-06 | 2.0e-04 | 554 | 152 | 10 | ADTRP,ANXA2P2,CDKN1B,DUSP10,FGF2,PLAUR,PLEK,TNFAIP3,TNFRSF12A,XBP1 |
| GO_CELLULAR_RESPONSE_TO_PEPTIDE | 8.8e-06 | 2.0e-04 | 554 | 388 | 16 | ARHGEF2,ATP6V0D2,CFLAR,CPEB2,HDAC9,ICAM1,IL1B,KLF3,NCK1,PPARG,PRLR,RIPK2,SOCS1,STAT5A,XBP1,ZFP36L1 |
| GO_T_CELL_PROLIFERATION | 8.8e-06 | 2.0e-04 | 554 | 187 | 11 | ARG2,BTN3A1,CEBPB,ELF4,IDO1,IL1B,IL6,IRF1,MAD1L1,NCK1,RIPK2 |
| GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 8.9e-06 | 2.0e-04 | 554 | 92 | 8 | ADORA2A,BIRC2,CFLAR,NGF,PLAUR,PTGS2,TNFAIP8,VEGFA |
| GO_REGULATION_OF_PROTEIN_BINDING | 9.0e-06 | 2.1e-04 | 554 | 224 | 12 | ANXA2P2,BAMBI,BMP2,CCPG1,CRBN,CSF3,CSNK1E,DVL1,IFIT1,IFIT2,PHLDA2,RIPK2 |
| GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION | 9.5e-06 | 2.2e-04 | 554 | 154 | 10 | ADTRP,ARG2,C5AR2,HDAC9,IL1B,NLRP3,PIM3,RSAD2,TNFAIP3,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_PROTEOLYSIS_INVOLVED_IN_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 9.5e-06 | 2.2e-04 | 554 | 122 | 9 | BAG6,CCDC22,CSNK1E,DVL1,NUB1,NUPR1,RNF144B,RNF185,TRIB1 |
| GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 9.6e-06 | 2.2e-04 | 554 | 93 | 8 | CSF3,ETS1,HCLS1,INHBA,ISG15,JAG1,TRIB1,ZFP36L1 |
| GO_RESPONSE_TO_OXYGEN_LEVELS | 9.7e-06 | 2.2e-04 | 554 | 391 | 16 | BIRC2,BMP2,CDKN1B,CFLAR,CPEB2,CPEB4,DDIT4,ETS1,HYOU1,ICAM1,KCNMA1,PPARG,PTGS2,SLC11A2,VEGFA,ZFP36L1 |
| GO_NUCLEOTIDE_BINDING_OLIGOMERIZATION_DOMAIN_CONTAINING_2_SIGNALING_PATHWAY | 9.8e-06 | 2.2e-04 | 554 | 13 | 4 | INAVA,NFKBIA,RIPK2,TNFAIP3 |
| GO_GLAND_DEVELOPMENT | 9.9e-06 | 2.2e-04 | 554 | 437 | 17 | BMP2,CDKN1B,CEBPB,CFLAR,DNAAF1,ELF3,ETS1,HOXB9,LMO4,MAD1L1,PRLR,SMAD2,SNAI2,STAT5A,TNFAIP3,VEGFA,XBP1 |
| GO_PLACENTA_DEVELOPMENT | 1.0e-05 | 2.3e-04 | 554 | 155 | 10 | BIRC2,CDKN1B,CEBPB,CSF2,PHLDA2,PPARG,PRDM1,PTGS2,TCF23,ZFP36L1 |
| GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | 1.0e-05 | 2.3e-04 | 554 | 123 | 9 | ARG2,CFLAR,ICAM1,IL1B,INAVA,PTGS2,PTX3,SLC7A2,ZC3H12A |
| GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS | 1.1e-05 | 2.5e-04 | 554 | 352 | 15 | C17orf99,ICAM1,IL13RA2,IL1B,IL6,JAG1,NFKB2,NFKBIZ,NLRP3,RELB,RIPK2,RSAD2,TNFAIP3,UNC13D,ZC3H12A |
| GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 1.1e-05 | 2.4e-04 | 554 | 439 | 17 | ASB1,BIRC2,BMPR1B,CDKN1B,CEBPB,CSF2,ICAM1,INHBA,NUPR1,PHLDA2,PPARG,PRDM1,PTGS2,PTX3,TCF23,VEGFA,ZFP36L1 |
| GO_VIRAL_GENOME_REPLICATION | 1.2e-05 | 2.6e-04 | 554 | 125 | 9 | HMGA2,IFIT1,ISG15,PPIB,RAB5A,RSAD2,TNIP1,TRIM38,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 1.3e-05 | 2.9e-04 | 554 | 47 | 6 | DDX58,DHX58,IFIH1,ISG15,RELB,TNFAIP3 |
| GO_NUCLEOTIDE_BINDING_OLIGOMERIZATION_DOMAIN_CONTAINING_1_SIGNALING_PATHWAY | 1.3e-05 | 2.9e-04 | 554 | 5 | 3 | NFKBIA,RIPK2,TNFAIP3 |
| GO_POSITIVE_REGULATION_OF_BIOMINERALIZATION | 1.3e-05 | 2.9e-04 | 554 | 47 | 6 | ACVR2B,AMTN,BMP2,BMPR1B,CEBPB,ISG15 |
| GO_PROTEIN_POLYMERIZATION | 1.4e-05 | 3.0e-04 | 554 | 273 | 13 | ARF1,ARPC2,CATIP,CDKN1B,CHMP4A,CSF3,EML2,HCLS1,ICAM1,JMY,NCK1,NPHS1,TTC17 |
| GO_REGULATION_OF_CELLULAR_LOCALIZATION | 1.4e-05 | 3.1e-04 | 554 | 802 | 24 | ANXA2P2,ARF1,BBC3,COMMD1,CSNK1E,CXCL10,DVL1,ERLEC1,GSTO1,HCLS1,IL13RA2,IL1B,JSRP1,LRIG2,MAD1L1,PIM3,PTGS2,RBM4,SP100,TOMM7,UBE2J1,UNC13D,ZC3H12A,ZFP36L1 |
| GO_REGULATION_OF_VIRAL_GENOME_REPLICATION | 1.4e-05 | 3.1e-04 | 554 | 98 | 8 | HMGA2,IFIT1,ISG15,PPIB,RSAD2,TNIP1,TRIM38,ZC3H12A |
| GO_ENDOTHELIAL_CELL_MIGRATION | 1.5e-05 | 3.2e-04 | 554 | 275 | 13 | ADTRP,ANXA3,CDH13,ETS1,FGF2,HDAC9,PPARG,PTGS2,S100P,SP100,STAT5A,VEGFA,ZC3H12A |
| GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 1.5e-05 | 3.3e-04 | 554 | 860 | 25 | ANXA2P2,ARF1,ATP5MGL,ATP6V0D2,BHLHA15,C15orf48,CATSPER3,CNKSR3,COMMD1,COX7A2L,CXCL10,FGF2,GSTO1,JSRP1,KCNH6,KCNMA1,KCNQ3,SCN11A,SLC11A2,SLC15A3,SLC25A37,SLC33A1,SLC9A4,SLC9A8,TRPM6 |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 1.5e-05 | 3.3e-04 | 554 | 499 | 18 | ATP6V0D2,CHMP4A,DRAM1,DRAM2,IKBKG,MFSD8,NBR1,NRBF2,NUPR1,PRKAG1,RAB5A,RIPK2,RNF185,TOMM7,VPS37C,WDR41,XBP1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | 1.6e-05 | 3.4e-04 | 554 | 29 | 5 | C3AR1,IL1A,IL1B,IL6,PTGS2 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 1.7e-05 | 3.6e-04 | 554 | 1146 | 30 | ALOXE3,ARG2,CIRBP,CPEB2,CPEB4,EIF4EBP3,FTSJ1,GSAP,HM13,IL6,KRT17,KYNU,LARP6,MRPS24,NCK1,NFE2L1,NGF,ORMDL1,PER1,QKI,RBM3,RBM4,RPL41,RPS17,SEC11C,TMED10,TNIP1,WARS1,ZC3H12A,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | 1.7e-05 | 3.6e-04 | 554 | 131 | 9 | ADORA2A,ADTRP,ARG2,CEBPB,IDO1,IRF1,MAD1L1,SOCS1,ZC3H12A |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 1.7e-05 | 3.6e-04 | 554 | 503 | 18 | ADORA2A,ARF1,ARPC2,CSF3,DRD5,HCLS1,ICAM1,JMY,KCNMA1,NCK1,NGF,NPHS1,PLEK,PTGS2,RAB5A,SOD2,TNFRSF12A,VEGFA |
| GO_RESPONSE_TO_COLD | 1.7e-05 | 3.6e-04 | 554 | 49 | 6 | CIRBP,CXCL10,METRNL,NFE2L1,NFKBIA,PPARG |
| GO_INTERLEUKIN_1_BETA_PRODUCTION | 1.9e-05 | 4.0e-04 | 554 | 102 | 8 | ARG2,IL1B,INAVA,NLRC4,NLRP3,RIPK2,TNFAIP3,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 1.9e-05 | 4.0e-04 | 554 | 50 | 6 | CCDC22,PER1,TNFAIP3,TNIP1,TNIP3,ZC3H12A |
| GO_MESODERM_DEVELOPMENT | 2.0e-05 | 4.2e-04 | 554 | 134 | 9 | ACVR2B,ETS2,HMGA2,IKZF1,INHBA,SMAD2,TBX6,VEGFA,ZFP36L1 |
| GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | 2.0e-05 | 4.2e-04 | 554 | 204 | 11 | ADORA2A,ARG2,CEBPB,IDO1,IL13RA2,INHBA,IRF1,MAD1L1,SOCS1,TNFAIP3,ZC3H12A |
| GO_NEGATIVE_REGULATION_OF_SECRETION | 2.0e-05 | 4.2e-04 | 554 | 243 | 12 | ADTRP,ARG2,C5AR2,HDAC9,IL13RA2,IL1B,INHBA,NLRP3,PIM3,RSAD2,TNFAIP3,ZC3H12A |
| GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | 2.1e-05 | 4.4e-04 | 554 | 205 | 11 | ARF1,ARPC2,CATIP,CSF3,HCLS1,ICAM1,JMY,NCK1,NPHS1,PLEK,TTC17 |
| GO_ADAPTIVE_IMMUNE_RESPONSE | 2.1e-05 | 4.4e-04 | 554 | 663 | 21 | ARG2,BTN3A1,C17orf99,DUSP10,ICAM1,IL13RA2,IL1B,IL6,IRF1,JAG1,NFKB2,NFKBIZ,NLRP3,PRDM1,RELB,RIPK2,RSAD2,TFE3,TNFAIP3,UNC13D,ZC3H12A |
| GO_CELL_CYCLE_PROCESS | 2.1e-05 | 4.4e-04 | 554 | 1399 | 34 | ARF1,ARHGEF2,ARID3A,AURKC,BAG6,C14orf39,CCNG2,CDK7,CDKN1B,CECR2,CHMP4A,CSNK1E,DYNC1I2,DYRK3,HMGA2,IL1A,IL1B,INHBA,IRF1,JMY,MAD1L1,MAP3K20,MEI1,MOV10L1,NFE2L1,PLK5,PRDM7,PRKAG1,STAG3L4,STAMBP,SYCE3,TOM1L1,UBE2E1,ZFP36L1 |
| GO_INTERFERON_BETA_PRODUCTION | 2.1e-05 | 4.4e-04 | 554 | 51 | 6 | DDX58,IFIH1,IRF1,RELB,RIPK2,TRIM38 |
| GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 2.2e-05 | 4.5e-04 | 554 | 1047 | 28 | ANXA2P2,ARHGEF15,ARHGEF2,BHLHA15,BHLHE41,BMP2,CDKN1B,CFLAR,CXCL10,DUSP10,HMGA2,IL1B,IL6,INHBA,IRF1,JAG1,LRIG2,NBR1,NFKBIA,PPARG,SNAI2,SOCS1,TBX6,TRIB1,VEGFA,XBP1,ZC3H12A,ZFP36L1 |
| GO_POSITIVE_REGULATION_OF_P38MAPK_CASCADE | 2.2e-05 | 4.5e-04 | 554 | 31 | 5 | BMP2,GADD45B,IL1B,VEGFA,ZC3H12A |
| GO_REGULATION_OF_AUTOPHAGY | 2.2e-05 | 4.5e-04 | 554 | 328 | 14 | ATP6V0D2,CHMP4A,DRAM1,DRAM2,IKBKG,MFSD8,NUPR1,PRKAG1,RAB5A,RIPK2,TOMM7,WDR41,XBP1,ZC3H12A |
| GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | 2.2e-05 | 4.5e-04 | 554 | 31 | 5 | ARG2,IDO1,IL6,NLRP3,RSAD2 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 2.3e-05 | 4.6e-04 | 554 | 564 | 19 | BBC3,CHMP4A,HCLS1,MON1B,NFKBIA,PECR,PTGS2,RPL41,RPS17,SEC61G,SRP54,TIMM17B,TNFAIP3,TNPO1,TOMM7,TSPAN10,TXNIP,VPS37C,ZC3H12A |
| GO_LIPID_METABOLIC_PROCESS | 2.3e-05 | 4.7e-04 | 554 | 1405 | 34 | ABHD1,ADTRP,ALG12,ALOX5AP,ALOXE3,ARF1,B3GNT5,BMP2,EDF1,FGF2,HSD11B1,IL1B,MBOAT1,MTMR7,NFE2L1,NPAS2,NRBF2,OCRL,ORMDL1,OSBP,PECR,PLA2G4C,PLEK,PNPLA1,PPARG,PRDX6,PRKAG1,PRLR,PTGS2,QKI,RAB5A,SNAI2,SOCS1,XBP1 |
| GO_RESPONSE_TO_INTERLEUKIN_1 | 2.3e-05 | 4.6e-04 | 554 | 207 | 11 | CEBPB,ETS1,ICAM1,IKBKG,IL1A,IL1B,IL6,LCN2,NFKBIA,RIPK2,ZC3H12A |
| GO_CELLULAR_RESPONSE_TO_VIRUS | 2.4e-05 | 4.8e-04 | 554 | 52 | 6 | ARF1,BIRC2,DDX58,DHX58,IFIH1,ZC3H12A |
| GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | 2.4e-05 | 4.9e-04 | 554 | 16 | 4 | IDO1,IL6,NLRP3,RSAD2 |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 2.4e-05 | 4.9e-04 | 554 | 669 | 21 | ANXA2P2,ARF1,ARHGEF15,ARHGEF2,ARPC2,CATIP,CDKN1B,CFLAR,CSF3,DVL1,EML2,HCLS1,ICAM1,JMY,KRT17,NCK1,NPHS1,PHACTR1,PLEK,RND1,TTC17 |
Num: 18 (Pathways: 98 DK: 5)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (5) | CDC42BPA, CDK10, POMK, PSKH1, TSSK6 |
| Light Kinase (16) | CAMK1, CDK6, CHEK2, DCLK2, FASTK, LATS1, MAPK12, MAPK14, MOK, PIK3R4, PRKG2, RPS6KA4, RPS6KB2, STK25, TYK2, WNK4 |
| Non-kinase Count | 575 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1870 | 71 | ACTR2,ARID1A,ATF5,BAX,CAMK1,CAND2,CCAR1,CEBPD,CHEK2,CLOCK,DTX3L,ENDOG,ETV2,FLT3LG,FOXP3,GAL,GCN1,HNF4G,HOXA10,HOXB7,HOXC10,HOXD13,ICE2,IKZF4,JADE1,KDM4D,MAPK14,MAZ,MED24,MEIS2,MESP1,MZF1,NABP2,NKX2-5,NSD1,PATZ1,PCBD1,PITX1,PPP3CA,PRDM11,RAD50,RPRD1B,RPS6KA4,RPTOR,RUNX2,SETMAR,SHC1,SLX1A,SMARCA4,SMARCAD1,SOHLH2,SP1,SPAG8,SRF,SSBP4,TAF8,TBL1XR1,TCF12,TCF4,TDRD3,TET1,TGFB3,TNFRSF1A,TNFSF13,TRA2A,UBTF,ZFAT,ZFHX4,ZFX,ZNF341,ZNF462 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1988 | 71 | ABCA2,ACTR2,ARID1A,ATF5,CAMK1,CAND2,CCAR1,CEBPD,CHEK2,CLOCK,CTDNEP1,DTX3L,ETV2,FLT3LG,FOXP3,GAL,GCN1,HNF4G,HOXA10,HOXB7,HOXC10,HOXD13,ICE2,IKZF4,JADE1,LARP1,MAPK14,MAZ,MED24,MEIS2,MESP1,MZF1,NAT10,NKX2-5,NSD1,PATZ1,PCBD1,PITX1,PPP3CA,PRDM11,RCC1L,RPRD1B,RPS6KA4,RPS6KB2,RPTOR,RUNX2,SAMD4A,SHC1,SMARCA4,SMARCAD1,SOHLH2,SP1,SPAG8,SRF,SSBP4,TAF8,TARBP2,TBL1XR1,TCF12,TCF4,TDRD3,TET1,TGFB3,TNFRSF1A,UBTF,WIZ,ZFAT,ZFHX4,ZFX,ZNF341,ZNF462 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1710 | 63 | ACTR2,ARID1A,ATF5,CAMK1,CAND2,CCAR1,CEBPD,CHEK2,CLOCK,DTX3L,ETV2,FLT3LG,FOXP3,GAL,GCN1,HNF4G,HOXA10,HOXB7,HOXC10,HOXD13,ICE2,IKZF4,JADE1,MAPK14,MAZ,MED24,MEIS2,MESP1,MZF1,NKX2-5,NSD1,PATZ1,PCBD1,PITX1,PPP3CA,PRDM11,RPRD1B,RPS6KA4,RPTOR,RUNX2,SHC1,SMARCA4,SMARCAD1,SOHLH2,SP1,SPAG8,SRF,SSBP4,TAF8,TBL1XR1,TCF12,TCF4,TDRD3,TET1,TGFB3,TNFRSF1A,TRA2A,UBTF,ZFAT,ZFHX4,ZFX,ZNF341,ZNF462 |
| GO_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 596 | 1223 | 49 | ANAPC15,ARID1A,ASCC3,CENPC,CHAMP1,CLOCK,CTBP1,DCLRE1C,DTX3L,FOXP3,H2AC4,H2BC7,H2BC9,H4C1,HDAC7,HMG20A,JADE1,JADE2,KDM4D,KIF25,LATS1,MBD2,MSH3,MSL1,NABP2,NAT10,NSD1,OTUB1,P3H4,PCGF2,PCGF3,PPP5C,PRDM5,PRMT7,RAD50,RPS6KA4,SETDB2,SETMAR,SLX1A,SMARCA4,SMARCAD1,TBL1XR1,TDRD3,TET1,TREX1,TSSK6,VPS72,ZNF462,ZNF830 |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1859 | 62 | ABCA2,ADAL,AGPAT3,ALG10,ALG8,ATP5IF1,ATP5MC3,ATP5MF,CARD9,CEPT1,CHCHD1,COASY,COX15,CPS1,DCAKD,DIO2,DPH1,EEF1A2,FARS2,FKRP,FOXP3,GAMT,GCN1,GORASP1,GSTM1,HACD4,IGF2BP2,LARP1,LCLAT1,MGST1,MOGS,MRPL23,MRPL34,MRPS18C,MRPS34,MTHFS,NAT10,NFS1,NOD1,OTC,PCBD1,PFAS,PIGK,PIGU,PLPP3,PNPO,POFUT1,POMK,RCC1L,RPS6KB2,SAMD4A,SDC1,SRP9,TARBP2,TARS2,TET1,TNFRSF1A,TREX1,UCKL1,UNK,VARS2,ZDHHC5 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 596 | 1029 | 43 | ARID1A,BAX,CASP8,DCHS1,DYNC2H1,ENDOG,ETV2,FLT3LG,HOXA10,HOXA6,HOXB7,HOXC10,HOXC5,HOXD13,KEAP1,LATS1,MBD2,MBNL1,MESP1,NDUFA2,NKX2-5,NRP1,PALB2,PCGF2,PDCD6,PFN1,PHACTR4,PITX1,POFUT1,RPL7L1,RUNX2,SEMA4C,SETDB2,SLC39A1,SRF,TAF8,TBL1XR1,TCTN1,TET1,TGFB3,UNK,ZFAT,ZNF830 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1962 | 62 | ABCA2,ABHD16A,ACY1,ADAL,AGPAT3,AK6,ATP5MC3,ATP5MF,BDH1,CARNMT1,COASY,COQ2,COQ4,CPS1,CPT1B,CYP11A1,DCAKD,ECHS1,EGFLAM,FADS2,FARS2,FBP1,GAMT,GNB3,HACD4,HYI,LCLAT1,MAPK14,MCCC2,MSRA,MTHFS,NDUFS6,NFS1,NUDT17,NUDT19,OGG1,OSBPL7,OTC,PCBD1,PCCA,PDE4B,PDSS2,PFAS,PFKL,PNPO,POFUT1,PPIP5K2,PTGR2,RAD50,SDHA,SIRT5,SLC25A10,SLC2A9,SLC35B4,SMARCAD1,SOGA1,SP1,TARS2,TNFRSF1A,TREX1,UCKL1,VARS2 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 0.0e+00 | 0.0e+00 | 596 | 649 | 33 | ARID1A,CASP8,DCHS1,ENDOG,ETV2,HOXA6,HOXB7,HOXC5,KEAP1,LATS1,MBNL1,MESP1,NDUFA2,NKX2-5,PALB2,PCGF2,PDCD6,PFN1,PHACTR4,POFUT1,RPL7L1,RUNX2,SEMA4C,SLC39A1,SRF,TAF8,TBL1XR1,TCTN1,TET1,TGFB3,UNK,ZFAT,ZNF830 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1005 | 41 | ALDH16A1,BDH1,COX15,COX7B,CPT1B,CTBP1,CYP11A1,DHRS11,DIO2,DUS2,ECHS1,FADS2,GYS1,HIGD2A,KDM4D,MAPK14,MGST1,MSRA,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,PCBD1,PFKL,PHKA1,PNPO,PTGR2,RSBN1L,SDHA,SLC25A10,TET1,TMX4,TREX1,TXNRD2,UQCR10,UQCRFS1P1 |
| GO_RNA_PROCESSING | 0.0e+00 | 0.0e+00 | 596 | 917 | 38 | ARL6IP4,CCAR1,DUS2,ELP1,ELP5,ERI3,FARS2,FASTK,INTS14,LSM1,MBNL1,MBNL3,METTL8,NAT10,NSUN6,PDCD7,PPP3CA,PRMT7,PRMT9,PRORP,PRPF31,PTBP1,RBM23,RPL7L1,RPRD1B,RRP36,SNRPE,SRSF8,SSU72,TARBP2,TRA2A,TRMT5,TRMT61B,TRUB1,TSR3,URM1,ZFC3H1,ZNF830 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 596 | 1470 | 50 | ARID1A,ATF5,ATN1,CCAR1,CDK6,CEBPD,CLOCK,CTBP1,CYREN,FBP1,FOXP3,H4C1,HDAC7,HDGF,HMG20A,IKZF4,LARP1,MAPK14,MBD2,MEIS2,MEPCE,MESP1,MSH3,MZF1,NAT10,NELFCD,NKX2-5,NSD1,OGG1,OTUB1,PATZ1,PCGF2,PITX1,PKP3,PPP3CA,PRDM11,PRDM5,PTBP1,RAD50,RUNX2,SETDB2,SHC1,SLX1A,SMARCA4,SP2,SRF,TBL1XR1,TET1,VPS72,ZFHX4 |
| GO_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 596 | 795 | 35 | ARID1A,CENPC,CLOCK,CTBP1,DTX3L,FOXP3,H2AC4,H2BC7,H2BC9,H4C1,HDAC7,HMG20A,JADE1,JADE2,KDM4D,MBD2,MSL1,NSD1,OTUB1,PCGF2,PCGF3,PPP5C,PRDM5,PRMT7,RPS6KA4,SETDB2,SETMAR,SMARCA4,SMARCAD1,TBL1XR1,TDRD3,TET1,TSSK6,VPS72,ZNF462 |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 596 | 528 | 28 | AFG3L2,ATP5IF1,ATP5MC3,ATP5MF,ATPAF1,BAX,CASP8,CAV2,COX18,FMC1,MICALL2,MIGA2,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,PMPCA,POLDIP2,RCC1L,SIRT5,TOMM40,UQCR10,WDR35 |
| GO_CELL_CYCLE | 0.0e+00 | 1.0e-07 | 596 | 1864 | 57 | ACTR2,ANAPC15,ATF5,ATRIP,BAX,CAMK1,CAV2,CCAR1,CCNB3,CDC25B,CDK10,CDK6,CDKN2C,CENPC,CHAMP1,CHEK2,CLOCK,CTBP1,CTDNEP1,EME2,FLT3LG,JADE1,KIF25,LATS1,LRRCC1,MAPK12,MAPK14,MEIS2,MEPCE,MOK,MSH3,NABP2,P3H4,PCGF2,PHACTR4,PIK3R4,POLDIP2,PPP3CA,PPP5C,PRDM11,PRDM5,RAD50,RNF167,RPRD1B,RPRM,RPTOR,SDCCAG8,SETDB2,SETMAR,SMARCAD1,SPAG8,TMEM14B,TREX1,TUBGCP6,WIZ,YTHDC2,ZNF830 |
| GO_ATP_SYNTHESIS_COUPLED_ELECTRON_TRANSPORT | 0.0e+00 | 1.0e-07 | 596 | 97 | 13 | COX15,COX7B,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,SDHA,UQCR10 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 1.0e-07 | 596 | 1782 | 55 | ACTR2,AMER1,ATP5IF1,ATPAF1,BAX,CAND2,CASP8,CDC42EP4,CENPC,COL16A1,COX15,COX18,DDX28,EMILIN1,FBP1,FMC1,GORASP1,H2BC7,H2BC9,H4C1,IKZF4,KIF25,LATS1,MBD2,MGST1,MICALL2,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,OTC,PDCD6,PFKL,PFN1,PPP5C,PRMT7,PRPF31,SH3BGR,SMARCA4,SMARCAD1,SNRPE,TARBP2,TCF4,TNFRSF1A,TOGARAM1,TRMT61B,TUBGCP6,UBTF,UQCR10,WIZ |
| GO_OXIDATIVE_PHOSPHORYLATION | 0.0e+00 | 1.0e-07 | 596 | 144 | 15 | ATP5MC3,ATP5MF,COX15,COX7B,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,SDHA,UQCR10 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 1.0e-07 | 596 | 1258 | 44 | ADNP,ALG8,BAX,CAMK1,CDC42BPA,CDK10,CHEK2,CLOCK,CTBP1,DCLK2,DPH1,EEF1AKMT3,EGFLAM,FKBP10,FKBP3,FOXP3,HMG20A,JADE1,JADE2,KDM4D,LATS1,MAPK12,MAPK14,METAP1D,MSL1,NAA11,NRP1,NSD1,P3H4,PCGF2,PRDM5,PRKG2,PRMT7,PRMT9,RPS6KA4,RPTOR,SETDB2,SETMAR,SHC1,SIRT5,THBS4,TNFRSF1A,TSSK6,TYK2 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 5.0e-07 | 596 | 1673 | 51 | ABCA2,ARID1A,ATF5,ATN1,CCAR1,CDK6,CEBPD,CHEK2,CLOCK,CTBP1,EMILIN1,FBP1,FOXP3,H4C1,HDAC7,HDGF,HMG20A,IGF2BP2,IKZF4,LARP1,MBD2,MEIS2,MEPCE,MESP1,MSH3,MZF1,NAT10,NELFCD,NKX2-5,NSD1,PATZ1,PCGF2,PITX1,PRDM11,PRDM5,RUNX2,SAMD4A,SETDB2,SHC1,SMARCA4,SOGA1,SP2,SRF,SRP9,TBL1XR1,TET1,UNK,VPS72,WDR35,ZFHX4,ZNF830 |
| GO_RESPIRATORY_ELECTRON_TRANSPORT_CHAIN | 0.0e+00 | 5.0e-07 | 596 | 115 | 13 | COX15,COX7B,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,SDHA,UQCR10 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 9.0e-07 | 596 | 1198 | 41 | ACTR2,ATF5,CAMK1,CEBPD,CLOCK,ETV2,FLT3LG,FOXP3,GAL,GCN1,HNF4G,HOXA10,HOXB7,HOXC10,HOXD13,IKZF4,MAPK14,MEIS2,MESP1,MZF1,NKX2-5,PATZ1,PITX1,PPP3CA,RPRD1B,RPS6KA4,RUNX2,SMARCA4,SOHLH2,SP1,SPAG8,SRF,SSBP4,TBL1XR1,TCF12,TCF4,TET1,TGFB3,TNFRSF1A,ZFAT,ZNF462 |
| GO_REPRODUCTION | 0.0e+00 | 1.1e-06 | 596 | 1457 | 46 | ACTR2,ADNP,ARID1A,BAX,CASP8,CCNB3,CDC25B,CENPC,CLOCK,COL16A1,CTDNEP1,DNAH11,EME2,ETV2,GAMT,HOXA10,HOXD13,MAPK14,MBD2,MGST1,MMP23B,MORN2,MSH3,P3H4,PAQR7,PATZ1,PCSK4,PLPP3,PRMT7,PTGFR,RAD50,SDC1,SOHLH2,SPAG8,SPATA9,SPIN3,SYDE1,TARBP2,TESMIN,TGFB3,TSSK6,TUBGCP6,UBE2Q1,YTHDC2,ZFAT,ZNF830 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 1.3e-06 | 596 | 1267 | 42 | ACTR2,ANAPC15,ANK1,ATF5,ATP5IF1,BAX,BST2,C2CD5,CASP8,CAV2,CCDC88A,CDC42EP4,CDK10,CTBP1,FOXP3,KDM4D,KIF25,LATS1,LRFN4,MICALL2,MYCBP2,NABP2,NAT10,NRP1,NSD1,OTUB1,PFN1,PHPT1,PRDM5,RAD50,RPS6KA4,SDC1,SDCCAG8,SETMAR,SLX1A,SYDE1,TET1,TGFB3,TOGARAM1,TREX1,UBQLN2,WDR35 |
| GO_ATP_METABOLIC_PROCESS | 0.0e+00 | 1.9e-06 | 596 | 303 | 19 | ATP5IF1,ATP5MC3,ATP5MF,COX15,COX7B,FBP1,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,PFKL,SDHA,TREX1,UQCR10 |
| GO_TRNA_MODIFICATION | 0.0e+00 | 2.1e-06 | 596 | 86 | 11 | DUS2,ELP1,ELP5,METTL8,NAT10,NSUN6,PRORP,TRMT5,TRMT61B,TRUB1,URM1 |
| GO_ELECTRON_TRANSPORT_CHAIN | 0.0e+00 | 2.3e-06 | 596 | 185 | 15 | COX15,COX7B,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,SDHA,TXNRD2,UQCR10,UQCRFS1P1 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 2.6e-06 | 596 | 1880 | 53 | ABCA2,ADNP,AMER1,BAX,CAMK1,CARD9,CAV2,CCDC88A,CCNB3,CDC25B,CDK10,CDKN2C,CHEK2,CTBP1,DDT,DTX3L,DUS2,EMILIN1,FIZ1,FLT3LG,FOXP3,GCN1,GORASP1,HMG20A,KDM4D,LATS1,MAPK14,MYCBP2,NOD1,NRP1,NSD1,OTUB1,PDCD6,PEBP1,PHACTR4,PLPP3,PPP1R36,PPP5C,PRDM11,PRDM5,PTBP1,RAD50,RGS3,RPS6KA4,RPTOR,SEMA4C,SHC1,STK25,TARBP2,TET1,TGFB3,THBS4,TNFRSF1A |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 2.8e-06 | 596 | 1724 | 50 | ABCA2,ADNP,AMER1,ATP5IF1,BAX,CAMK1,CARD9,CASP8,CAV2,CCDC88A,CDC25B,CDK10,CHEK2,CTBP1,DDT,FIZ1,FLT3LG,FOXP3,GORASP1,KEAP1,LARP1,LATS1,LRRTM3,MAPK12,MAPK14,MYCBP2,NAT10,NOD1,NRP1,OSBPL7,PDCD6,PRDM5,PTBP1,RAD50,RCC1L,RPS6KA4,RPS6KB2,RPTOR,SAMD4A,SEMA4C,SHC1,STK25,TARBP2,TET1,TGFB3,THBS4,TNFRSF1A,UBQLN2,USP13,WDR35 |
| GO_DNA_METABOLIC_PROCESS | 0.0e+00 | 2.8e-06 | 596 | 925 | 34 | ACTR2,AP5S1,ASCC3,ATRIP,BAX,CHEK2,CYREN,DCLRE1C,DTX3L,EME2,ENDOG,ERI2,ERI3,FOXP3,H4C1,KDM4D,MBD2,MSH3,NABP2,NAT10,OGG1,OTUB1,PALB2,PMS1,PPP5C,PRMT7,RAD50,SETMAR,SLX1A,SMARCAD1,TET1,TNFSF13,TREX1,ZNF830 |
| GO_DOUBLE_STRAND_BREAK_REPAIR | 0.0e+00 | 3.1e-06 | 596 | 251 | 17 | ACTR2,AP5S1,CHEK2,CYREN,DCLRE1C,DTX3L,EME2,H4C1,KDM4D,NABP2,OGG1,OTUB1,PALB2,RAD50,SETMAR,SLX1A,SMARCAD1 |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 3.4e-06 | 596 | 1224 | 40 | ANAPC15,ATF5,ATRIP,BAX,CAV2,CCNB3,CDC25B,CDK10,CDK6,CDKN2C,CHEK2,CLOCK,CTBP1,EME2,FLT3LG,JADE1,KIF25,LATS1,MAPK12,MAPK14,MEIS2,MEPCE,MOK,NABP2,PCGF2,PHACTR4,PIK3R4,POLDIP2,PRDM11,RNF167,RPRD1B,RPRM,RPTOR,SDCCAG8,SETMAR,TMEM14B,TREX1,WIZ,YTHDC2,ZNF830 |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 0.0e+00 | 3.7e-06 | 596 | 987 | 35 | ABCA2,AMER1,ANP32A,ATP5IF1,BAX,CHEK2,DTX3L,EEF1A2,ENDOG,FBP1,FMC1,IGF2BP2,KEAP1,KIF25,LARP1,LATS1,MAPK14,MYCBP2,NOD1,OSBPL7,PKP3,POLDIP2,PSME3IP1,RPTOR,SAMD4A,SOGA1,TNFSF13,TREX1,TRIM13,TRIM65,UBQLN2,USP13,VPS26B,WDR24,YOD1 |
| GO_GROWTH | 0.0e+00 | 3.9e-06 | 596 | 990 | 35 | ADNP,AFG3L2,ALCAM,ATF5,BST2,CDKN2C,FBP1,GAMT,HOXD13,JADE1,LATS1,MAPK14,MESP1,NDUFS6,NKX2-5,NRP1,PALB2,PPP3CA,PRDM11,RC3H2,RERG,RPTOR,SEMA3D,SEMA4C,SHC1,SMARCA4,SOCS2,SP2,SRF,TAF8,TARBP2,TBL1XR1,TM4SF4,WDR11,ZNF830 |
| GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_NADH_TO_UBIQUINONE | 0.0e+00 | 4.0e-06 | 596 | 55 | 9 | NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6 |
| GO_COVALENT_CHROMATIN_MODIFICATION | 0.0e+00 | 4.2e-06 | 596 | 473 | 23 | CLOCK,CTBP1,DTX3L,FOXP3,HDAC7,JADE1,JADE2,KDM4D,MBD2,MSL1,NSD1,OTUB1,PCGF2,PCGF3,PPP5C,PRDM5,PRMT7,RPS6KA4,SETDB2,SETMAR,SMARCAD1,TBL1XR1,TET1 |
| GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY | 0.0e+00 | 4.7e-06 | 596 | 96 | 11 | COX18,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,UQCR10 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 5.2e-06 | 596 | 1994 | 54 | ADNP,BAX,CAMK1,CARD9,CAV2,CCDC88A,CCNB3,CDC25B,CDC42BPA,CDK10,CDK6,CDKN2C,CHEK2,CTBP1,DCLK2,DDT,DUS2,EMILIN1,FASTK,FIZ1,FLT3LG,GCN1,KDM4D,LATS1,MAPK12,MAPK14,MOK,NOD1,NRP1,NSD1,PEBP1,PHKA1,PIK3R4,PLPP3,POMK,PPP5C,PRDM11,PRKG2,PSKH1,RAD50,RGS3,RPS6KA4,RPS6KB2,RPTOR,SEMA4C,SHC1,STK25,TARBP2,TGFB3,THBS4,TNFRSF1A,TSSK6,TYK2,WNK4 |
| GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 0.0e+00 | 7.5e-06 | 596 | 376 | 20 | CASP8,ENDOG,ETV2,KEAP1,LATS1,MBNL1,NDUFA2,PALB2,PCGF2,RPL7L1,SLC39A1,SRF,TAF8,TBL1XR1,TCTN1,TET1,TGFB3,UNK,ZFAT,ZNF830 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 7.6e-06 | 596 | 532 | 24 | ATP5IF1,ATP5MC3,ATP5MF,BDH1,COX15,COX7B,FBP1,GYS1,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,PFKL,PHKA1,SDHA,TREX1,TXNRD2,UQCR10,UQCRFS1P1 |
| GO_TRNA_PROCESSING | 0.0e+00 | 9.4e-06 | 596 | 128 | 12 | DUS2,ELP1,ELP5,FARS2,METTL8,NAT10,NSUN6,PRORP,TRMT5,TRMT61B,TRUB1,URM1 |
| GO_TRNA_METABOLIC_PROCESS | 1.0e-07 | 9.5e-06 | 596 | 183 | 14 | DUS2,ELP1,ELP5,FARS2,METTL8,NAT10,NSUN6,PRORP,TARS2,TRMT5,TRMT61B,TRUB1,URM1,VARS2 |
| GO_CELLULAR_RESPIRATION | 1.0e-07 | 1.2e-05 | 596 | 187 | 14 | COX15,COX7B,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,SDHA,TREX1,UQCR10 |
| GO_NADH_DEHYDROGENASE_COMPLEX_ASSEMBLY | 1.0e-07 | 1.2e-05 | 596 | 64 | 9 | NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6 |
| GO_DNA_REPAIR | 1.0e-07 | 1.3e-05 | 596 | 551 | 24 | ACTR2,AP5S1,ASCC3,ATRIP,CHEK2,CYREN,DCLRE1C,DTX3L,EME2,H4C1,KDM4D,MSH3,NABP2,OGG1,OTUB1,PALB2,PMS1,PPP5C,RAD50,SETMAR,SLX1A,SMARCAD1,TREX1,ZNF830 |
| GO_NCRNA_METABOLIC_PROCESS | 1.0e-07 | 1.3e-05 | 596 | 471 | 22 | DUS2,ELP1,ELP5,ERI3,FARS2,INTS14,MEPCE,METTL8,NAT10,NSUN6,PRORP,RC3H2,RPL7L1,RRP36,TARBP2,TARS2,TRMT5,TRMT61B,TRUB1,TSR3,URM1,VARS2 |
| GO_RNA_MODIFICATION | 1.0e-07 | 1.3e-05 | 596 | 161 | 13 | DUS2,ELP1,ELP5,MEPCE,METTL8,NAT10,NSUN6,PRORP,TRMT5,TRMT61B,TRUB1,TSR3,URM1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 1.0e-07 | 1.8e-05 | 596 | 1220 | 38 | ACTR2,ADNP,ANK1,ATP5IF1,BAX,C2CD5,CAMK1,CASP8,CCDC88A,CDC42EP4,COL16A1,COLGALT1,CTBP1,EMILIN1,ENDOG,FLT3LG,FOXP3,LRRTM3,MAPK14,MICALL2,NABP2,NLGN2,NRP1,PFN1,PPP3CA,PRDM5,RAD50,RPS6KA4,SDC1,SLX1A,SRF,SSH1,STK25,TET1,TGFB3,TOGARAM1,TOR1A,WDR35 |
| GO_METHYLATION | 1.0e-07 | 1.9e-05 | 596 | 366 | 19 | CARNMT1,EEF1AKMT3,GAMT,KDM4D,MBD2,MEPCE,METTL8,NSD1,NSUN6,PRDM11,PRDM5,PRMT7,PRMT9,PRORP,SETDB2,SETMAR,TET1,TRMT5,TRMT61B |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 1.0e-07 | 1.8e-05 | 596 | 831 | 30 | ABCA2,AMER1,ANP32A,ATP5IF1,BAX,DTX3L,EEF1A2,ENDOG,IGF2BP2,KEAP1,KIF25,LARP1,LATS1,MAPK14,NOD1,OSBPL7,PKP3,POLDIP2,PSME3IP1,RPTOR,SAMD4A,SOGA1,TNFSF13,TRIM13,TRIM65,UBQLN2,USP13,VPS26B,WDR24,YOD1 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 1.0e-07 | 2.0e-05 | 596 | 1930 | 51 | ABCA2,ANK1,ARHGEF16,ATP5IF1,BAX,C12orf50,C2CD5,CAMK1,CASP8,CCDC88A,CHAMP1,COX18,CRACR2B,CTDNEP1,DCHS1,DCLK2,DTX3L,DYNC2H1,FAM53B,GORASP1,LATS1,MAPK14,MICALL1,MICALL2,NABP2,NLGN2,NRP1,NUDT19,PDCD6,PEX10,PEX26,PIGK,PIGU,PIK3R4,PKP3,PMPCA,PPP3CA,PRKG2,SRP9,SSH1,TAF8,TCTN1,TGFBRAP1,TM9SF3,TNFRSF1A,TOMM40,TOR1A,VPS26B,WDR11,WDR35,YOD1 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 2.0e-07 | 2.3e-05 | 596 | 1036 | 34 | ACTR2,ATPAF1,CDC42EP4,CENPC,COX15,COX18,DDX28,FMC1,H2BC7,H2BC9,H4C1,LATS1,MBD2,MICALL2,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,PFN1,PRMT7,PRPF31,SMARCA4,SNRPE,TARBP2,TCF4,TOGARAM1,TUBGCP6,UBTF,UQCR10 |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 2.0e-07 | 3.1e-05 | 596 | 856 | 30 | ACTR2,AP5S1,ASCC3,ATRIP,BAX,CHEK2,CLOCK,CYREN,DCLRE1C,DTX3L,EME2,H4C1,KDM4D,MAPK12,MAPK14,MSH3,NABP2,OGG1,OTUB1,PALB2,PMS1,PPP5C,RAD50,SETMAR,SHISA5,SLX1A,SMARCAD1,TNFRSF1A,TREX1,ZNF830 |
| GO_DEVELOPMENTAL_GROWTH | 2.0e-07 | 3.6e-05 | 596 | 677 | 26 | ADNP,AFG3L2,ALCAM,ATF5,GAMT,HOXD13,LATS1,MAPK14,MESP1,NDUFS6,NKX2-5,NRP1,PALB2,PPP3CA,RC3H2,SEMA3D,SEMA4C,SOCS2,SP2,SRF,TAF8,TARBP2,TBL1XR1,TM4SF4,WDR11,ZNF830 |
| GO_EMBRYONIC_MORPHOGENESIS | 3.0e-07 | 3.9e-05 | 596 | 592 | 24 | ARID1A,BAX,DYNC2H1,ETV2,HOXA10,HOXA6,HOXB7,HOXC10,HOXD13,LATS1,MBNL1,MESP1,NKX2-5,PCGF2,PFN1,PHACTR4,PITX1,RUNX2,SEMA4C,SETDB2,SLC39A1,SRF,TCTN1,TGFB3 |
| GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 3.0e-07 | 4.1e-05 | 596 | 278 | 16 | COX15,COX7B,GYS1,NDUFA2,NDUFA3,NDUFB10,NDUFB2,NDUFB7,NDUFC1,NDUFS2,NDUFS5,NDUFS6,PHKA1,SDHA,TREX1,UQCR10 |
| GO_BLASTOCYST_DEVELOPMENT | 3.0e-07 | 4.4e-05 | 596 | 99 | 10 | ETV2,LATS1,NDUFA2,PALB2,RPL7L1,SRF,TAF8,TBL1XR1,TET1,ZNF830 |
| GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 3.0e-07 | 4.4e-05 | 596 | 353 | 18 | ACTR2,BAX,CYREN,DTX3L,ENDOG,FOXP3,KDM4D,MBD2,MSH3,NABP2,NAT10,OGG1,OTUB1,RAD50,SETMAR,SLX1A,SMARCAD1,TNFSF13 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 4.0e-07 | 4.6e-05 | 596 | 1823 | 48 | ABCA2,ADNP,BAX,CAMK1,CARD9,CAV2,CCDC88A,CCNB3,CDC25B,CDK10,CDKN2C,CHEK2,DDT,DUS2,EEF1A2,EMILIN1,FBP1,FIZ1,FLT3LG,GCN1,GNB3,KDM4D,LATS1,MAPK14,NOD1,NRP1,NSD1,PEBP1,PHACTR4,PIK3R4,PLPP3,PPP1R36,PPP5C,PRDM11,PTBP1,RAD50,RGS3,RPS6KA4,RPTOR,SEMA4C,SHC1,SOCS2,STK25,TARBP2,TGFB3,THBS4,TNFRSF1A,TREX1 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 4.0e-07 | 4.6e-05 | 596 | 1280 | 38 | ARID1A,ATF5,ATN1,CCAR1,CDK6,CEBPD,CLOCK,CTBP1,FBP1,FOXP3,H4C1,HDAC7,HDGF,HMG20A,IKZF4,MBD2,MEIS2,MEPCE,MESP1,MZF1,NELFCD,NKX2-5,NSD1,PATZ1,PCGF2,PITX1,PRDM11,PRDM5,RUNX2,SETDB2,SHC1,SMARCA4,SP2,SRF,TBL1XR1,TET1,VPS72,ZFHX4 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 4.0e-07 | 5.2e-05 | 596 | 1721 | 46 | ABCA2,ACTR2,ARID1A,C2CD5,CASP8,CAV2,CHEK2,CLOCK,COL16A1,CPS1,CYP11A1,EMILIN1,ENDOG,ETV2,GABRG2,GAL,HNF4G,HOXD13,LARP1,LATS1,MBD2,MICALL1,NOD1,OGG1,OTC,PAQR7,PDCD7,PDE4B,PPP5C,PTBP1,PTGFR,RERG,RPTOR,RUNX2,SDC1,SHC1,SLC8A1,SMARCA4,SOCS2,SOGA1,SP1,SRF,SSH1,TGFB3,TGFBRAP1,TREX1 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 4.0e-07 | 5.3e-05 | 596 | 1033 | 33 | ABCA2,ABHD16A,ADAL,AGPAT3,AK6,ATP5MC3,ATP5MF,CEPT1,COASY,CPS1,DCAKD,FBP1,GNB3,LCLAT1,MCCC2,NFS1,NUDT17,OGG1,PDE4B,PFAS,PFKL,PIGK,PIGU,PIK3R4,PLPP3,PNPO,PPIP5K2,RAD50,SH3YL1,SMARCAD1,SOCS2,TREX1,UCKL1 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 4.0e-07 | 5.3e-05 | 596 | 1781 | 47 | ADNP,ARFGAP2,ARHGEF16,BAX,CAMK1,CARD9,CASP8,CAV2,CCDC88A,CDC25B,CLOCK,DTX3L,EEF1A2,GAL,GCN1,GORASP1,KDM4D,MAPK12,MAPK14,MBD2,MSH3,MYO9B,NOD1,NRP1,PDCD6,PFN1,PHACTR4,PIK3R4,PLPP3,PPP3CA,RAD50,RGS12,RGS3,RPS6KA4,RPTOR,SETMAR,SHC1,SIPA1L3,SMARCA4,SRF,STK25,SYDE1,TGFB3,TRIM13,TRIM14,WDR35,WNK4 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 4.0e-07 | 5.3e-05 | 596 | 1135 | 35 | ACTR2,C2CD5,CARD9,CAV2,COL16A1,CPS1,CYP11A1,GABRG2,GAL,GSTM1,LARP1,MAPK14,MGST1,NOD1,OGG1,OTC,PDE4B,PPP3CA,PPP5C,RPTOR,SDC1,SHC1,SLC8A1,SOCS2,SOGA1,SP1,SSH1,TMUB1,TOR1A,TREX1,TRIM13,UBQLN2,USP13,YOD1,ZCCHC3 |
| GO_CELL_PROJECTION_ASSEMBLY | 5.0e-07 | 5.7e-05 | 596 | 567 | 23 | ACTR2,ARMC9,B9D2,CCDC88A,CDC42EP4,CDK10,DYNC2H1,EMP3,KIAA0586,NRP1,PFN1,SDCCAG8,SH3YL1,SRF,TCTN1,TGFB3,TMEM138,TOGARAM1,TXNDC15,UNC119B,WDR11,WDR35,WDR90 |
| GO_LIPID_METABOLIC_PROCESS | 5.0e-07 | 5.9e-05 | 596 | 1405 | 40 | ABCA2,ABHD16A,AGPAT3,ALG10,ALG8,BAX,CEPT1,COQ2,CPS1,CPT1B,CTDNEP1,CYP11A1,DHRS11,ECHS1,EEF1A2,FADS2,FMC1,GAL,GNB3,HACD4,LCLAT1,MAPK14,NDUFS6,NUDT19,OSBPL7,PCCA,PDSS2,PIGK,PIGU,PIK3R4,PLCXD1,PLPP3,PTGR2,SDC1,SH3YL1,SOCS2,SP1,TBL1XR1,TNFRSF1A,TREX1 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 6.0e-07 | 6.4e-05 | 596 | 1410 | 40 | ABCA2,AMER1,ANAPC15,ANP32A,ATP5IF1,BAX,CASP8,CHEK2,CLOCK,DTX3L,EEF1A2,ENDOG,ERI3,IGF2BP2,KEAP1,LARP1,LATS1,LSM1,MAPK14,MYCBP2,OAS2,OSBPL7,PHKA1,PIK3R4,PKP3,PNRC2,PSME3IP1,RNF167,SAMD4A,SDC1,SETMAR,TBL1XR1,TMUB1,TNFSF13,TOR1A,TREX1,TRIM13,UBQLN2,USP13,YOD1 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 7.0e-07 | 7.9e-05 | 596 | 1698 | 45 | ABCA2,ACTR2,ADNP,C2CD5,CARD9,CASP8,CAV2,CHEK2,COL16A1,CPS1,CYP11A1,ENDOG,GAL,HOXD13,LARP1,MAPK14,MBD2,MGST1,NOD1,OGG1,OSBPL7,OTC,PCGF2,PDE4B,PFKL,PHPT1,PLSCR3,PPP3CA,PPP5C,PTGFR,RPTOR,SDC1,SHC1,SLC8A1,SMARCA4,SOCS2,SOGA1,SP1,SRF,SSH1,STK25,TGFB3,TREX1,TXNRD2,WDR35 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 7.0e-07 | 7.9e-05 | 596 | 1869 | 48 | AMER1,ARMC9,ATP5IF1,BAX,BST2,CARD9,CASP8,CAV2,CDK10,CTDNEP1,DDT,DYNC2H1,EPN2,FAM53B,GAL,GPR174,GRAP2,MAPK14,MAZ,MBD2,MESP1,NLGN2,NOD1,NRP1,PHPT1,PPP5C,PTBP1,RC3H2,RNF220,RPTOR,SEMA4C,SH3BGR,SHC1,SHISA5,SMARCA4,SOCS2,SSH1,STK25,TBL1XR1,TGFB3,TNFRSF1A,TRAF3IP2,TRIM13,TXNDC15,UBQLN2,WDR24,WDR35,ZCCHC3 |
| GO_RESPONSE_TO_DRUG | 8.0e-07 | 8.5e-05 | 596 | 1061 | 33 | ABCA2,ACTR2,CARD9,CASP8,CAV2,CHEK2,CPS1,ENDOG,FBP1,GAL,LARP1,MAPK14,MGST1,NOD1,OGG1,OTC,PCGF2,PDE4B,PFAS,PMS1,PPP3CA,PPP5C,SDC1,SLC25A10,SLC25A24,SLC8A1,SNCG,SSH1,STK25,TGFB3,TOR1A,TREX1,WDR35 |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 8.0e-07 | 9.1e-05 | 596 | 499 | 21 | ATP5IF1,EEF1A2,KEAP1,KIF25,LARP1,LIX1L,NOD1,OSBPL7,PIK3R4,POLDIP2,RPTOR,SOGA1,TOMM40,TOMM6,TRIM13,TRIM65,UBQLN2,USP13,VPS26B,WDR24,YOD1 |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 9.0e-07 | 9.2e-05 | 596 | 723 | 26 | ABCA2,ADAL,BDH1,COQ2,COQ4,CPS1,FADS2,FBP1,GAMT,HACD4,MTHFS,NUDT17,OGG1,OSBPL7,OTC,PCBD1,PDE4B,PDSS2,PNPO,PPIP5K2,SIRT5,SLC25A10,SLC35B4,SOGA1,SP1,UCKL1 |
| GO_NCRNA_PROCESSING | 9.0e-07 | 9.4e-05 | 596 | 378 | 18 | DUS2,ELP1,ELP5,ERI3,FARS2,INTS14,METTL8,NAT10,NSUN6,PRORP,RPL7L1,RRP36,TARBP2,TRMT5,TRMT61B,TRUB1,TSR3,URM1 |
| GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | 1.0e-06 | 1.0e-04 | 596 | 636 | 24 | ADAL,ANP32A,BAX,CARNMT1,DIO2,ENDOG,ERI3,IGF2BP2,LARP1,LSM1,MAPK14,MTHFS,NUDT17,OAS2,OGG1,PCBD1,PDE4B,PKP3,PNRC2,SAMD4A,SETMAR,TET1,TNFSF13,TREX1 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 1.0e-06 | 1.0e-04 | 596 | 973 | 31 | ABCA2,ACTR2,ARID1A,CARD9,CASP8,CAV2,CHEK2,CLOCK,CPS1,ENDOG,GABRG2,HNF4G,HOXD13,LARP1,LATS1,MBD2,OGG1,OSBPL7,OTC,PAQR7,PDCD7,PDE4B,PPP5C,PTGFR,SDC1,SLC8A1,SMARCA4,SOCS2,SSH1,TGFB3,ZCCHC3 |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 1.1e-06 | 1.1e-04 | 596 | 1180 | 35 | ABCA2,AMER1,ANAPC15,ANP32A,ATP5IF1,BAX,CASP8,CHEK2,CLOCK,DTX3L,ENDOG,ERI3,IGF2BP2,KEAP1,LARP1,LATS1,LSM1,MAPK14,OAS2,OSBPL7,PKP3,PNRC2,PSME3IP1,RNF167,SAMD4A,SETMAR,TBL1XR1,TMUB1,TNFSF13,TOR1A,TREX1,TRIM13,UBQLN2,USP13,YOD1 |
| GO_MACROMOLECULE_METHYLATION | 1.1e-06 | 1.1e-04 | 596 | 306 | 16 | EEF1AKMT3,KDM4D,MBD2,MEPCE,METTL8,NSD1,NSUN6,PRDM5,PRMT7,PRMT9,PRORP,SETDB2,SETMAR,TET1,TRMT5,TRMT61B |
| GO_MITOTIC_CELL_CYCLE | 1.2e-06 | 1.2e-04 | 596 | 1030 | 32 | ANAPC15,BAX,CAV2,CCNB3,CDC25B,CDK10,CDK6,CDKN2C,CENPC,CHAMP1,CHEK2,CTDNEP1,EME2,JADE1,KIF25,LATS1,MEIS2,MEPCE,NABP2,POLDIP2,PPP3CA,PPP5C,PRDM5,RPRM,RPTOR,SDCCAG8,SETDB2,SETMAR,TMEM14B,TUBGCP6,YTHDC2,ZNF830 |
| GO_REGULATION_OF_PHOSPHORYLATION | 1.3e-06 | 1.2e-04 | 596 | 1625 | 43 | ADNP,BAX,CAMK1,CARD9,CAV2,CCDC88A,CCNB3,CDC25B,CDK10,CDKN2C,CHEK2,DDT,DUS2,EEF1A2,EMILIN1,FBP1,FIZ1,FLT3LG,GCN1,KDM4D,LATS1,MAPK14,NOD1,NRP1,NSD1,PEBP1,PIK3R4,PLPP3,PPP5C,PRDM11,RAD50,RGS3,RPS6KA4,RPTOR,SEMA4C,SHC1,SOCS2,STK25,TARBP2,TGFB3,THBS4,TNFRSF1A,TREX1 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 1.5e-06 | 1.4e-04 | 596 | 1146 | 34 | ABCA2,CARNMT1,CHCHD1,CPS1,DIO2,DPH1,EEF1A2,FARS2,GCN1,GSTM1,IGF2BP2,LARP1,LRRTM3,MCCC2,MGST1,MRPL23,MRPL34,MRPS18C,MRPS34,MTHFS,NAT10,OTC,PCCA,PCSK4,RCC1L,RPS6KB2,SAMD4A,SRP9,TARBP2,TARS2,TNFRSF1A,TRHDE,UNK,VARS2 |
| GO_MRNA_METABOLIC_PROCESS | 1.5e-06 | 1.4e-04 | 596 | 840 | 28 | ANP32A,ARL6IP4,CCAR1,IGF2BP2,LARP1,LSM1,MAPK14,MBNL1,MBNL3,PDCD7,PKP3,PNRC2,PRMT7,PRMT9,PRPF31,PTBP1,RBM23,RPRD1B,SAMD4A,SNRPE,SRF,SRSF8,SSU72,TNFSF13,TRA2A,TRMT61B,TRUB1,ZNF830 |
| GO_LOCOMOTION | 1.6e-06 | 1.5e-04 | 596 | 1984 | 49 | ACKR4,ALCAM,ARHGEF16,BAX,BST2,CAV2,CCAR1,CCDC88A,CDC42BPA,CDK6,CYSLTR1,DCHS1,DDT,DNAH11,EGFLAM,ELP1,ELP5,EMILIN1,GYPC,HDAC7,MAPK14,MAZ,MESP1,MYCBP2,NRP1,PDCD6,PDE4B,PFN1,PHACTR4,PHPT1,PLPP3,POMK,PPP3CA,PTPRF,SDC1,SDCCAG8,SEMA3D,SEMA4C,SHC1,SLC7A6,SLC8A1,SP1,SRF,SSH1,SYDE1,THBS4,TOR1A,TRIM13,UNK |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1.8e-06 | 1.7e-04 | 596 | 1703 | 44 | AMER1,BAX,BST2,CASP8,CAV2,CDK6,CHEK2,CLOCK,CYREN,DDT,EMILIN1,EPN2,FBP1,FOXP3,HDAC7,JADE1,LATS1,LRRC14,MAPK14,MAZ,MESP1,NKX2-5,NRP1,OGG1,OTUB1,PCGF2,PDCD6,PEBP1,PHACTR4,PHPT1,RC3H2,RGS12,RGS3,RUNX2,SEMA3D,SEMA4C,SMARCA4,SOCS2,TARBP2,TGFB3,TNFRSF1A,TREX1,UBQLN2,YOD1 |
| GO_MULTICELLULAR_ORGANISM_GROWTH | 2.1e-06 | 1.9e-04 | 596 | 150 | 11 | AFG3L2,ATF5,GAMT,NDUFS6,PALB2,RC3H2,SOCS2,SP2,TARBP2,TBL1XR1,WDR11 |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 2.3e-06 | 2.1e-04 | 596 | 1064 | 32 | ABCA2,ABHD16A,AGPAT3,ALG10,ALG8,BAX,CEPT1,COQ2,CPS1,CPT1B,CTDNEP1,ECHS1,FADS2,GNB3,HACD4,LCLAT1,MAPK14,NDUFS6,NUDT19,PCCA,PDSS2,PIGK,PIGU,PIK3R4,PLPP3,PTGR2,SDC1,SH3YL1,SOCS2,TBL1XR1,TNFRSF1A,TREX1 |
| GO_PATTERN_SPECIFICATION_PROCESS | 2.3e-06 | 2.1e-04 | 596 | 446 | 19 | DCHS1,DNAH11,DYNC2H1,HOXA10,HOXA6,HOXB7,HOXC10,HOXC5,HOXD13,MESP1,NKX2-5,NRP1,PALB2,PCGF2,POFUT1,PSKH1,SETDB2,SRF,TCTN1 |
| GO_DNA_RECOMBINATION | 2.4e-06 | 2.1e-04 | 596 | 288 | 15 | ACTR2,AP5S1,DCLRE1C,EME2,ENDOG,FOXP3,KDM4D,MSH3,NABP2,PALB2,RAD50,SLX1A,SMARCAD1,TNFSF13,TREX1 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 2.4e-06 | 2.1e-04 | 596 | 624 | 23 | ACTR2,ANK1,ATP5IF1,BAX,C2CD5,CASP8,CCDC88A,CDC42EP4,CTBP1,FOXP3,MICALL2,NABP2,NRP1,PFN1,PRDM5,RAD50,RPS6KA4,SDC1,SLX1A,TET1,TGFB3,TOGARAM1,WDR35 |
| GO_NON_RECOMBINATIONAL_REPAIR | 2.6e-06 | 2.2e-04 | 596 | 97 | 9 | CYREN,DCLRE1C,DTX3L,H4C1,KDM4D,OGG1,RAD50,SETMAR,SLX1A |
| GO_REGULATION_OF_AUTOPHAGY | 2.6e-06 | 2.2e-04 | 596 | 328 | 16 | ATP5IF1,EEF1A2,KEAP1,KIF25,LARP1,NOD1,OSBPL7,POLDIP2,RPTOR,SOGA1,TRIM13,TRIM65,UBQLN2,USP13,VPS26B,WDR24 |
| GO_CELL_CYCLE_PROCESS | 3.0e-06 | 2.5e-04 | 596 | 1399 | 38 | ACTR2,ANAPC15,ATF5,BAX,CAV2,CCNB3,CDC25B,CDK10,CDK6,CDKN2C,CENPC,CHAMP1,CHEK2,CTDNEP1,EME2,JADE1,KIF25,LATS1,MAPK12,MEPCE,MSH3,NABP2,P3H4,PCGF2,PIK3R4,PPP3CA,RAD50,RPRD1B,RPRM,RPTOR,SDCCAG8,SETMAR,SMARCAD1,TMEM14B,TUBGCP6,WIZ,YTHDC2,ZNF830 |
| GO_CELLULAR_NITROGEN_COMPOUND_CATABOLIC_PROCESS | 3.1e-06 | 2.5e-04 | 596 | 587 | 22 | ADAL,ANP32A,BAX,CARNMT1,ENDOG,ERI3,IGF2BP2,LARP1,LSM1,MAPK14,MTHFS,NUDT17,OAS2,OGG1,PDE4B,PKP3,PNRC2,SAMD4A,SETMAR,TET1,TNFSF13,TREX1 |
| GO_NEUROGENESIS | 3.1e-06 | 2.5e-04 | 596 | 1625 | 42 | ABCA2,ACTR2,ADNP,AFG3L2,ALCAM,ATF5,BAX,CAMK1,CCDC88A,CDK6,CDKN2C,DCHS1,DCLK2,DYNC2H1,EGFLAM,GORASP1,HMG20A,HOXC10,LSM1,MESP1,MICALL1,MICALL2,MYCBP2,NKX2-5,NRP1,POMK,PPP3CA,PRDM5,PTPRF,RUNX2,SDCCAG8,SEMA3D,SEMA4C,SHC1,SOCS2,SRF,STK25,TCF12,TCF4,TCTN1,TOR1A,UNK |
| GO_MITOCHONDRIAL_TRANSPORT | 3.3e-06 | 2.7e-04 | 596 | 258 | 14 | ABCB10,AFG3L2,ATP5IF1,ATP5MC3,ATP5MF,BAX,CASP8,COX18,CPT1B,MICALL2,PMPCA,SLC25A10,SLC25A24,TOMM40 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 3.4e-06 | 2.7e-04 | 596 | 637 | 23 | ANAPC15,ATF5,ATRIP,BAX,CDK6,CDKN2C,CHEK2,CLOCK,EME2,JADE1,KIF25,LATS1,MAPK12,MAPK14,NABP2,PCGF2,RNF167,RPRM,RPTOR,SETMAR,TREX1,YTHDC2,ZNF830 |
| GO_PEPTIDE_METABOLIC_PROCESS | 3.4e-06 | 2.7e-04 | 596 | 879 | 28 | ABCA2,CARNMT1,CHCHD1,DIO2,DPH1,EEF1A2,FARS2,GCN1,GSTM1,IGF2BP2,LARP1,LRRTM3,MGST1,MRPL23,MRPL34,MRPS18C,MRPS34,NAT10,PCSK4,RCC1L,RPS6KB2,SAMD4A,SRP9,TARBP2,TARS2,TRHDE,UNK,VARS2 |
| GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | 3.6e-06 | 2.8e-04 | 596 | 297 | 15 | BAX,DCLRE1C,EME2,ENDOG,ERI2,ERI3,OGG1,PNRC2,PRORP,RAD50,RRP36,SETMAR,SLX1A,TATDN3,TREX1 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 3.6e-06 | 2.8e-04 | 596 | 1301 | 36 | ABCA2,ABHD16A,ADAL,AMER1,ANAPC15,ATP5IF1,CARNMT1,CASP8,CHEK2,CLOCK,DIO2,DTX3L,EEF1A2,KEAP1,LATS1,MCCC2,MTHFS,MYCBP2,NUDT17,OGG1,OSBPL7,OTC,PCBD1,PDE4B,PSME3IP1,RNF167,SDC1,TBL1XR1,TET1,TMUB1,TOR1A,TRHDE,TRIM13,UBQLN2,USP13,YOD1 |
| GO_RESPONSE_TO_HORMONE | 4.5e-06 | 3.4e-04 | 596 | 994 | 30 | ABCA2,ARID1A,C2CD5,CASP8,CAV2,CHEK2,CLOCK,CPS1,CYP11A1,ENDOG,GAL,HNF4G,HOXD13,LATS1,MBD2,OGG1,OTC,PAQR7,PDCD7,PPP5C,PTGFR,RERG,SDC1,SHC1,SMARCA4,SOCS2,SOGA1,SP1,SRF,TGFB3 |
Num: 9 (Pathways: 512 DK: 4)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (4) | EEF2K, PKMYT1, PRPF4B, RSKR |
| Light Kinase (23) | AKT1, ATR, BUB1B, CDC7, CHUK, CIT, EPHA3, FASTKD1, FASTKD2, FASTKD3, FASTKD5, GRK6, HASPIN, MAP3K7, PBK, PI4K2B, PLK1, PRKDC, RPS6KA1, STRADB, TRIM28, TTK, VRK1 |
| Non-kinase Count | 1112 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 1864 | 238 | AHCTF1,AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,APEX2,ASPM,ATAD5,ATR,AUNIP,AURKAIP1,BARD1,BIRC5,BLM,BMI1,BRCA1,BRD7,BRIP1,BUB1B,BUB3,CARM1,CCAR2,CCNE1,CCNF,CCP110,CDC20,CDC45,CDC5L,CDC7,CDCA2,CDCA3,CDCA8,CDK5RAP1,CDKN3,CENPE,CENPF,CENPJ,CENPS,CENPV,CENPX,CEP152,CEP192,CEP41,CEP78,CETN3,CHAF1A,CIT,CKS1B,CKS2,CUL2,DBF4,DBF4B,DCLRE1B,DDIAS,DDX12P,DDX3X,DHFR,DLGAP5,DNA2,DONSON,DSCC1,DSN1,E2F4,E2F8,ECT2,EED,EIF4E,EIF4G1,EME1,ERCC6L,ERH,ESCO2,EXO1,FAM83D,FANCA,FANCD2,FBXO5,FEN1,FIGN,FIGNL1,GEN1,GINS1,GPSM2,GTSE1,H2AX,HASPIN,HAUS3,HAUS8,HELLS,HIRA,KHDRBS1,KIF11,KIF14,KIF15,KIF18B,KIF20A,KIF20B,KIF22,KIF23,KIF2A,KIF4A,KNL1,KNTC1,LIG1,LSM10,MACROH2A1,MAD2L1,MCM10,MCM2,MCM5,MCM6,MCM8,MCMBP,MDM1,METTL3,MKI67,MLH1,MLH3,MRE11,MSH5,MSH6,MYB,MYBBP1A,MYBL1,MYBL2,MZT1,NCAPD2,NCAPD3,NCAPG,NCAPG2,NDC1,NDC80,NSUN2,OIP5,ORC1,ORC2,ORC5,PAGR1,PAXIP1,PBK,PCLAF,PER2,PIDD1,PIMREG,PKMYT1,PKP4,PLK1,PNPT1,POC1A,POLA1,POLA2,POLD1,POLE2,POLE3,PPAT,PPM1G,PPP1CC,PPP2R3B,PRIM1,PRKDC,PRPF19,PRPF40A,PSMD5,PSME3,PTTG1,RAD51C,RAD54B,RANBP1,REEP4,RFC2,RFC3,RFC4,RFC5,RIDA,RMI1,RPA1,RPA3,RPS6KA1,RRM2,RRP8,RRS1,RTEL1,SASS6,SEPTIN12,SGO1,SGO2,SIN3A,SKA3,SKP2,SLFN11,SMC1A,SMC5,SPAG5,SPC25,SPICE1,SSX2IP,STIL,STMN1,STRADB,SUV39H1,SUV39H2,SYCP1,TACC3,TERF2,TERT,TFDP1,TGFB2,THBS1,TICRR,TIMELESS,TRIP13,TTK,TUBA1B,TUBA4A,TUBB4B,TUBB6,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,TXLNG,TXNL4A,TYMS,UBE2L3,UBE2S,UHRF1,USP37,USP51,VRK1,WDHD1,WNT10B,WRAP73,XRCC2,XRCC3,YEATS4,ZWILCH |
| GO_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1399 | 204 | AHCTF1,AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ASPM,ATAD5,AUNIP,AURKAIP1,BARD1,BIRC5,BLM,BMI1,BRCA1,BRD7,BRIP1,BUB1B,BUB3,CARM1,CCNE1,CCNF,CCP110,CDC20,CDC45,CDC7,CDCA8,CDKN3,CENPE,CENPF,CENPJ,CENPS,CENPV,CENPX,CEP152,CEP192,CEP41,CEP78,CETN3,CIT,CKS1B,CKS2,CUL2,DBF4,DBF4B,DCLRE1B,DDIAS,DDX12P,DDX3X,DHFR,DLGAP5,DNA2,DONSON,DSCC1,DSN1,E2F4,E2F8,ECT2,EED,EIF4E,EIF4G1,EME1,ESCO2,FAM83D,FANCA,FANCD2,FBXO5,FEN1,FIGNL1,GEN1,GINS1,GPSM2,GTSE1,HASPIN,HAUS3,HAUS8,HIRA,KHDRBS1,KIF11,KIF14,KIF18B,KIF20A,KIF20B,KIF22,KIF23,KIF2A,KIF4A,KNL1,KNTC1,LIG1,LSM10,MACROH2A1,MAD2L1,MCM10,MCM2,MCM5,MCM6,MCM8,MCMBP,MDM1,MKI67,MLH1,MLH3,MRE11,MSH5,MSH6,MYBBP1A,MYBL1,MYBL2,MZT1,NCAPD2,NCAPD3,NCAPG,NDC1,NDC80,NSUN2,ORC1,ORC2,ORC5,PAGR1,PAXIP1,PCLAF,PIDD1,PKMYT1,PKP4,PLK1,PNPT1,POC1A,POLA1,POLA2,POLD1,POLE2,POLE3,PPAT,PPM1G,PPP2R3B,PRIM1,PRKDC,PRPF40A,PSMD5,PSME3,PTTG1,RAD51C,RAD54B,RANBP1,REEP4,RFC2,RFC3,RFC4,RFC5,RIDA,RMI1,RPA1,RPA3,RRM2,RRP8,RRS1,RTEL1,SASS6,SEPTIN12,SGO1,SGO2,SIN3A,SKP2,SLFN11,SMC1A,SMC5,SPAG5,SPC25,SPICE1,SSX2IP,STIL,STMN1,STRADB,SYCP1,TACC3,TERF2,TERT,TFDP1,TGFB2,THBS1,TICRR,TIMELESS,TRIP13,TTK,TUBA4A,TUBB4B,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,TXLNG,TYMS,UBE2L3,UBE2S,USP37,USP51,VRK1,WNT10B,WRAP73,XRCC2,XRCC3,ZWILCH |
| GO_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 1223 | 182 | ANAPC1,ANAPC4,APEX1,ASF1B,ATR,BEND3,BLM,BMI1,BRCA1,BRD7,BRIP1,BUB1B,BUB3,CARM1,CBX2,CCNE1,CDAN1,CDC20,CDC45,CDCA8,CENPE,CENPF,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,CHD7,CHTOP,CRTC2,DCLRE1B,DDX12P,DDX3X,DLGAP5,DNA2,DNMT1,DNMT3B,DSCC1,DSN1,EED,EPOP,ERCC6L,ESCO2,EXO1,FANCD2,FBL,FBXO5,FEN1,GATA2,GEN1,GINS1,GTF2F2,GTF2H3,GTF3C4,H1-3,H2AX,H2AZ1,H2AZ2,H3C1,HASPIN,HDAC2,HELLS,HIRA,HIRIP3,HMGB1,HMGN1,HNRNPC,ING5,INO80E,IPO4,IWS1,KIF14,KIF18B,KIF22,KIF23,KIF4A,KNL1,LEF1,LEO1,MACROH2A1,MAD2L1,MAP3K7,MBD3,MCM2,MCM5,MCM6,MCM8,MCMBP,MKI67,MLH1,MLH3,MRE11,MSH6,MTERF1,MTF2,MYB,NCAPD2,NCAPD3,NCAPG,NCAPG2,NDC1,NDC80,NOC2L,NUDT5,NUP107,NUP155,OIP5,PABPC1L,PAGR1,PARP1,PAXBP1,PAXIP1,PER2,PHB,PIF1,PLK1,POLA1,POLA2,POLD1,POLE2,POLE3,POLQ,PRIM1,PRKDC,PTGES3,PTMA,PTTG1,RAD51C,RAD54B,RBBP5,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,RRP8,RRS1,RTEL1,SAFB,SGO1,SGO2,SIN3A,SMC1A,SMC5,SMC6,SMCHD1,SPAG5,SRCAP,SSBP1,SUPT16H,SUV39H1,SUV39H2,SYCP1,TACC3,TAF5,TAF6L,TBL1X,TDG,TERF2,TERT,TOP1,TOP3B,TRIM28,TRIP13,TTK,TUBG1,TWNK,UBE2N,UHRF1,USP51,UTP3,VRK1,WDR5,WDR82,WRAP53,XRCC3,XRCC5,YEATS4 |
| GO_RNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1139 | 917 | 159 | AARS2,ADAT1,ANKRD16,AQR,AURKAIP1,BARD1,BMS1,C1QBP,CCAR2,CDC5L,CDK5RAP1,CHD7,CHTOP,CLNS1A,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,CTU2,DCPS,DDX51,DDX56,DHX15,DHX37,DNAJC8,EBNA1BP2,EFTUD2,ELAC2,ELAVL1,ELP6,ERI1,ESF1,EXOSC2,EXOSC8,FAM98B,FASTKD5,FBL,FDXACB1,FTSJ3,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2F2,GTF2H3,GTPBP3,HEATR1,HNRNPC,HNRNPR,HTATSF1,INTS2,INTS8,INTS9,ISG20L2,IVNS1ABP,IWS1,KHDRBS1,KRR1,LAS1L,LEO1,LSM10,LSM3,LSM6,LSM7,LYAR,MDN1,METTL2B,METTL3,MPHOSPH10,MRM1,MRM2,MRTO4,NCBP1,NCL,NOC4L,NOL10,NOL11,NOL6,NOL8,NOP56,NSUN2,NUFIP1,OSGEP,PA2G4,PABPC1L,PDCD11,PNN,PNPT1,POLR2B,POLR2D,POLR2F,POLR2K,POLR3K,POP5,PPIH,PPIL1,PPP1R8,PRKRA,PRPF19,PRPF38B,PRPF39,PRPF4,PRPF40A,PRPF4B,PSIP1,PTCD1,PUS3,PWP2,RBFA,RNGTT,RPP14,RRP1B,RRP8,RRS1,SAFB,SAFB2,SENP3,SF3B4,SFSWAP,SNRNP200,SNRNP40,SNRNP48,SNRNP70,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRRM1,SRSF10,SRSF9,SSB,SUGP2,SUV39H1,SYNCRIP,TBL3,TERT,TGS1,THOC3,TPRKB,TRMT10C,TRMT11,TSEN54,TTF2,TXNL4A,TYW1,URB1,UTP11,UTP20,UTP3,WDR12,WDR18,WDR3,WDR36,WDR74,WDR75,ZC3H13 |
| GO_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 925 | 149 | AKT1,APEX1,APEX2,APOBEC3B,AQR,ASTE1,ATAD5,ATP23,ATR,AUNIP,BARD1,BEND3,BLM,BRCA1,BRIP1,CCNE1,CDC45,CDC5L,CDC7,CENPF,CENPS,CENPX,CHAF1A,DCLRE1B,DCTPP1,DNA2,DNMT1,DNMT3B,DONSON,DSCC1,EME1,ERI1,ESCO2,EXO1,EXO5,FANCA,FANCB,FANCC,FANCD2,FANCL,FEN1,FIGN,FIGNL1,GATAD2A,GEN1,GINS1,GINS3,GTF2H3,H1-3,H2AX,HELLS,HMGB1,HMGN1,HNRNPC,HSPD1,IL7R,INO80E,KIF22,KLHL15,LEF1,LIG1,MBD3,MCM10,MCM2,MCM5,MCM6,MCM8,MLH1,MLH3,MRE11,MSH5,MSH6,NEIL2,NME1,NTHL1,ORC1,ORC2,ORC5,PAGR1,PARG,PARP1,PARPBP,PAXIP1,PCLAF,PHB,PIF1,POLA1,POLA2,POLD1,POLE2,POLE3,POLG2,POLQ,POLR2B,POLR2D,POLR2F,POLR2K,PRIM1,PRKDC,PRPF19,PTGES3,PTTG1,RAD51C,RAD54B,RFC2,RFC3,RFC4,RFC5,RMI1,RNASEH1,RPA1,RPA3,RTEL1,SLFN11,SMC1A,SMC5,SMC6,SMCHD1,SPRTN,SSRP1,SUPT16H,SYCP1,TDG,TEFM,TERF2,TERT,TFDP1,TICRR,TIMELESS,TK1,TONSL,TOP1,TOP3B,TREX2,TRIM28,TRIP13,TYMS,UBE2N,UBE2NL,UCHL5,UHRF1,USP10,USP51,WDHD1,WDR18,WRAP53,XRCC2,XRCC3,XRCC5 |
| GO_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 1030 | 156 | AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ATAD5,AURKAIP1,BIRC5,BLM,BRCA1,BRD7,BUB1B,BUB3,CARM1,CCNE1,CCNF,CCP110,CDC20,CDC45,CDC5L,CDC7,CDCA8,CDKN3,CENPE,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,CIT,CKS1B,CKS2,CUL2,DBF4,DBF4B,DCLRE1B,DDIAS,DDX3X,DHFR,DLGAP5,DNA2,DONSON,DSCC1,DSN1,E2F4,E2F8,ECT2,EIF4E,EIF4G1,EME1,FBXO5,GEN1,GINS1,GPSM2,GTSE1,HASPIN,HAUS3,HAUS8,HIRA,KHDRBS1,KIF11,KIF14,KIF15,KIF18B,KIF20A,KIF20B,KIF22,KIF23,KIF2A,KIF4A,KNTC1,LIG1,LSM10,MACROH2A1,MAD2L1,MCM10,MCM2,MCM5,MCM6,MCM8,MKI67,MRE11,MYB,MYBL1,MYBL2,MZT1,NCAPD2,NCAPD3,NCAPG,NDC80,ORC1,ORC2,ORC5,PBK,PIDD1,PKMYT1,PLK1,PNPT1,POC1A,POLA1,POLA2,POLE2,POLE3,PPAT,PRIM1,PRKDC,PSMD5,PSME3,PTTG1,RAD51C,RANBP1,REEP4,RPA1,RPA3,RRM2,RRS1,RTEL1,SGO1,SIN3A,SKA3,SKP2,SLFN11,SMC1A,SMC5,SPAG5,SPC25,SPICE1,STIL,STMN1,TACC3,TERT,TFDP1,TICRR,TRIP13,TTK,TUBA1B,TUBA4A,TUBB4B,TUBB6,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,TYMS,UBE2S,USP37,VRK1,WDHD1,WNT10B,WRAP73,XRCC2,XRCC3,YEATS4,ZWILCH |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 1139 | 856 | 134 | AKT1,APEX1,APEX2,AQR,ASTE1,ATAD5,ATP23,ATR,AUNIP,BARD1,BLM,BRCA1,BRIP1,CARM1,CCAR2,CDC45,CDC5L,CDC7,CENPS,CENPX,CHAF1A,DCLRE1B,DDIAS,DNA2,DONSON,E2F4,E2F8,ELL3,EME1,ESCO2,EXO1,EXO5,FANCA,FANCB,FANCC,FANCD2,FANCL,FBXO45,FBXO5,FEN1,FIGN,FIGNL1,GEN1,GTF2H3,GTSE1,H2AX,HMGB1,HMGN1,HPF1,INO80E,IRF3,KIF22,KLHL15,LIG1,MCM10,MCM2,MCM5,MCM6,MCM8,METTL3,MLH1,MLH3,MRE11,MRPS26,MRPS9,MSH5,MSH6,NEIL2,NTHL1,PAGR1,PARG,PARP1,PARPBP,PAXIP1,PCLAF,PIDD1,PIF1,PLK1,POLA1,POLD1,POLE2,POLE3,POLG2,POLQ,POLR2B,POLR2D,POLR2F,POLR2K,PRKDC,PRPF19,PTTG1,RAD51C,RAD54B,RBBP5,RFC2,RFC3,RFC4,RFC5,RMI1,RPA1,RPA3,RTEL1,SLFN11,SMC1A,SMC5,SMC6,SMCHD1,SPRTN,SSRP1,SUPT16H,SUV39H1,SYCP1,TDG,TERF2,TFDP1,TICRR,TIMELESS,TMEM109,TNFRSF1B,TONSL,TREX2,TRIM28,TRIP13,UBE2N,UBE2NL,UCHL5,UHRF1,USP10,USP51,WDHD1,WRAP53,XRCC2,XRCC3,XRCC5 |
| GO_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 551 | 107 | APEX1,APEX2,AQR,ASTE1,ATP23,ATR,AUNIP,BARD1,BLM,BRCA1,BRIP1,CDC45,CDC5L,CDC7,CENPS,CENPX,CHAF1A,DCLRE1B,DNA2,EME1,ESCO2,EXO1,EXO5,FANCA,FANCB,FANCC,FANCD2,FANCL,FEN1,FIGN,FIGNL1,GEN1,GTF2H3,H2AX,HMGB1,HMGN1,INO80E,KIF22,KLHL15,LIG1,MCM2,MCM5,MCM6,MCM8,MLH1,MLH3,MRE11,MSH5,MSH6,NEIL2,NTHL1,PAGR1,PARG,PARP1,PARPBP,PAXIP1,PCLAF,PIF1,POLA1,POLD1,POLE2,POLG2,POLQ,POLR2B,POLR2D,POLR2F,POLR2K,PRKDC,PRPF19,PTTG1,RAD51C,RAD54B,RFC2,RFC3,RFC4,RFC5,RMI1,RPA1,RPA3,RTEL1,SMC1A,SMC5,SMC6,SMCHD1,SPRTN,SSRP1,SUPT16H,SYCP1,TDG,TERF2,TICRR,TIMELESS,TONSL,TREX2,TRIM28,TRIP13,UBE2N,UBE2NL,UCHL5,UHRF1,USP10,USP51,WDHD1,WRAP53,XRCC2,XRCC3,XRCC5 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1139 | 419 | 92 | ATR,BMS1,C1QBP,CHD7,CLNS1A,CLP1,DDX31,DDX3X,DDX51,DDX56,DHX30,DHX37,EBNA1BP2,EIF3B,ERI1,ESF1,EXOSC2,EXOSC8,FASTKD2,FBL,FDXACB1,FTSJ3,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,HEATR1,HEATR3,ISG20L2,KRR1,LAS1L,LSM6,LTV1,LYAR,MDN1,MPHOSPH10,MRM1,MRM2,MRPL11,MRPS7,MRTO4,MTERF3,MYBBP1A,NCBP1,NOC2L,NOC4L,NOL10,NOL11,NOL6,NOL8,NOM1,NOP16,NOP56,NUFIP1,PA2G4,PDCD11,POLR2D,POP5,PRPF19,PRPF39,PSIP1,PTGES3,PWP2,RBFA,RRP1B,RRP8,RRS1,SENP3,SFSWAP,SNRNP200,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRSF10,SRSF9,SUV39H1,TBL3,TGS1,TXNL4A,URB1,UTP11,UTP20,UTP3,WDR12,WDR18,WDR3,WDR36,WDR74,WDR75 |
| GO_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1139 | 267 | 75 | ATAD5,ATR,BARD1,BLM,BRCA1,BRIP1,CACYBP,CCNE1,CDAN1,CDC45,CDC7,CENPS,CENPX,CHAF1A,DBF4,DBF4B,DNA2,DNAJA3,DONSON,DSCC1,DUT,E2F8,EME1,ESCO2,EXO1,FBXO5,FEN1,GEN1,GINS1,GINS3,ING5,LIG1,MCM10,MCM2,MCM5,MCM6,MCM8,MCMBP,MRE11,ORC1,ORC2,ORC5,PCLAF,PIF1,POLA1,POLA2,POLD1,POLE2,POLE3,POLG2,POLQ,PRIM1,RFC2,RFC3,RFC4,RFC5,RMI1,RPA1,RPA3,RRM2,RTEL1,SIN3A,SLFN11,SSBP1,SSRP1,SUPT16H,TERF2,TICRR,TIMELESS,TONSL,TOP1,TWNK,USP37,WDHD1,WDR18 |
| GO_NCRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 471 | 90 | AARS2,ADAT1,ANKRD16,BMS1,CDK5RAP1,CHD7,CLP1,CPSF4,CSTF2,CTU2,DARS2,DDX51,DDX56,DHX37,EBNA1BP2,ELAC2,ELP6,ERI1,ESF1,EXOSC2,EXOSC8,FAM98B,FBL,FDXACB1,FTSJ3,GEMIN4,GTPBP3,HEATR1,INTS2,INTS8,INTS9,ISG20L2,KRR1,LARS2,LAS1L,LSM6,LYAR,MARS2,MDN1,METTL2B,METTL3,MPHOSPH10,MRM1,MRM2,MRTO4,MYBL1,NARS2,NOC4L,NOL10,NOL11,NOL6,NOL8,NOP56,NSUN2,OSGEP,PA2G4,PDCD11,PNPT1,POLR3K,POP5,PRKRA,PTCD1,PUS3,PWP2,RARS1,RBFA,RPP14,RRP1B,RRP8,RRS1,SARS2,SENP3,SSB,SUV39H1,TBL3,TPRKB,TRMT10C,TRMT11,TSEN54,TYW1,URB1,UTP11,UTP20,UTP3,WDR12,WDR18,WDR3,WDR36,WDR74,WDR75 |
| GO_NCRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1139 | 378 | 82 | AARS2,ADAT1,ANKRD16,BMS1,CDK5RAP1,CHD7,CLP1,CPSF4,CSTF2,CTU2,DDX51,DDX56,DHX37,EBNA1BP2,ELAC2,ELP6,ERI1,ESF1,EXOSC2,EXOSC8,FAM98B,FBL,FDXACB1,FTSJ3,GEMIN4,GTPBP3,HEATR1,INTS2,INTS8,INTS9,ISG20L2,KRR1,LAS1L,LSM6,LYAR,MDN1,METTL2B,METTL3,MPHOSPH10,MRM1,MRM2,MRTO4,NOC4L,NOL10,NOL11,NOL6,NOL8,NOP56,NSUN2,OSGEP,PA2G4,PDCD11,POLR3K,POP5,PRKRA,PTCD1,PUS3,PWP2,RBFA,RPP14,RRP1B,RRP8,RRS1,SENP3,SSB,SUV39H1,TBL3,TPRKB,TRMT10C,TRMT11,TSEN54,TYW1,URB1,UTP11,UTP20,UTP3,WDR12,WDR18,WDR3,WDR36,WDR74,WDR75 |
| GO_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 637 | 100 | AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ATAD5,BLM,BRCA1,BRD7,BUB1B,BUB3,CARM1,CCNE1,CCNF,CCP110,CDC20,CDC45,CDC7,CDKN3,CENPE,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,CIT,CKS1B,CKS2,CUL2,DBF4,DBF4B,DDX3X,DHFR,DLGAP5,DONSON,E2F4,E2F8,EIF4E,EIF4G1,FAM83D,FBXO5,GEN1,GTSE1,HAUS3,HAUS8,KHDRBS1,KIF14,KNTC1,LSM10,MACROH2A1,MAD2L1,MCM10,MCM2,MCM5,MCM6,MCM8,MRE11,NDC80,ORC1,ORC2,ORC5,PAGR1,PAXIP1,PIDD1,PKMYT1,PLK1,POLA1,POLA2,POLE2,POLE3,PPAT,PRIM1,PRKDC,PSMD5,PSME3,RAD51C,RPA1,RPA3,RRM2,SIN3A,SKP2,SLFN11,TACC3,TERT,TFDP1,TICRR,TIMELESS,TRIP13,TTK,TUBA4A,TUBB4B,TUBG1,TYMS,UBE2L3,UBE2S,USP37,WNT10B,XRCC3 |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 1224 | 134 | AHCTF1,AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ASPM,ATAD5,ATR,AURKAIP1,BARD1,BLM,BMI1,BRCA1,BRD7,BRIP1,BUB1B,BUB3,CARM1,CCAR2,CCNE1,CCNF,CCP110,CDC20,CDC45,CDC5L,CDC7,CDK5RAP1,CDKN3,CENPE,CENPF,CENPJ,CENPV,CEP152,CEP192,CEP41,CEP78,CIT,CKS1B,CKS2,DBF4,DBF4B,DCLRE1B,DDIAS,DDX3X,DLGAP5,DNA2,DONSON,E2F4,E2F8,ECT2,EED,EIF4E,EIF4G1,EME1,FAM83D,FBXO5,FEN1,FIGNL1,GEN1,GPSM2,GTSE1,H2AX,HAUS3,HAUS8,KIF11,KIF14,KIF20A,KIF20B,KIF23,KNTC1,LSM10,MACROH2A1,MAD2L1,MDM1,METTL3,MKI67,MRE11,MYBBP1A,MYBL2,NDC80,NSUN2,ORC1,PAGR1,PAXIP1,PCLAF,PER2,PIDD1,PKMYT1,PKP4,PLK1,PNPT1,POC1A,PPM1G,PPP2R3B,PRKDC,PRPF19,PRPF40A,PSMD5,PSME3,PTTG1,RAD51C,RANBP1,RPA3,RRM2,RRP8,SIN3A,SKP2,SLFN11,SMC1A,SMC5,SPAG5,SPICE1,STIL,STRADB,TACC3,TERF2,TERT,TFDP1,TGFB2,THBS1,TICRR,TIMELESS,TRIP13,TTK,TUBA4A,TUBB4B,TUBG1,TXLNG,USP51,WNT10B,XRCC3,ZWILCH |
| GO_DNA_DEPENDENT_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1139 | 146 | 54 | ATAD5,BLM,CCNE1,CDC45,CDC7,CENPS,CENPX,DBF4,DBF4B,DNA2,DNAJA3,DONSON,DSCC1,E2F8,EME1,FBXO5,FEN1,GEN1,GINS1,GINS3,LIG1,MCM10,MCM2,MCM5,MCM6,MCMBP,MRE11,ORC1,ORC2,ORC5,POLA1,POLA2,POLD1,POLE2,POLE3,POLG2,POLQ,PRIM1,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,RTEL1,SLFN11,SSBP1,TERF2,TICRR,TIMELESS,TONSL,TWNK,WDHD1,WDR18 |
| GO_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 324 | 71 | ANAPC1,ANAPC4,BIRC5,BRCA1,BRIP1,BUB1B,BUB3,CCNE1,CDC20,CDCA2,CDCA8,CENPE,CENPF,CENPS,CENPX,DDX12P,DDX3X,DLGAP5,DSCC1,DSN1,ECT2,EME1,ESCO2,FAM83D,FANCD2,FBXO5,FEN1,GEN1,HASPIN,HIRA,KIF14,KIF18B,KIF22,KIF23,KIF4A,KNL1,MACROH2A1,MAD2L1,MCMBP,MKI67,MLH1,MLH3,MRE11,NCAPD2,NCAPD3,NCAPG,NDC1,NDC80,OIP5,PLK1,PTTG1,RAD51C,RMI1,RRS1,SGO1,SGO2,SKA3,SMC1A,SMC5,SMC6,SPAG5,SPC25,SPICE1,SYCP1,TACC3,TOP1,TOP3B,TRIP13,TTK,TUBG1,XRCC3 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 1782 | 156 | ACAD9,AHCTF1,ANLN,AP2S1,ARPC1A,ASF1B,ATL2,ATP23,ATR,BCS1L,BEND3,BLM,CAND1,CDC45,CENPE,CENPF,CENPH,CENPI,CENPJ,CENPL,CENPS,CENPU,CENPV,CENPX,CEP192,CHAF1A,CLNS1A,CLP1,CNIH3,COA1,CRTC2,CTSC,DDX3X,DHX30,DHX33,DNAAF4,DNAAF5,ECT2,EIF3B,EIF4G1,ELAVL1,FANCA,FANCC,FARP2,FASTKD2,FASTKD3,FBXO5,FKBP4,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2A2,GTF2H3,GTF3C5,H1-3,H2AX,H3C1,HELLS,HIRA,HMGB1,HPRT1,HSPD1,ICE1,IL1RAP,IPO4,KCNC4,KCNRG,KHDRBS1,KIF14,KNL1,KNTC1,KPNA3,LEF1,LEO1,LETM1,LYRM7,MACROH2A1,MCM2,MCM5,MCM6,MDN1,MRPL11,MRPS7,MRTO4,MZT1,NACC1,NCBP1,NCLN,NDC1,NDUFA12,NDUFAB1,NDUFAF5,NUFIP1,NUP107,OIP5,OPA1,OTUD6B,PARP1,PFKM,PLEKHG2,PNPT1,POLE3,POLQ,POLR2D,PPAT,PPIH,PPP6R3,PRPF19,PRPF39,PSIP1,PSMD5,PTGES3,PWP2,RASGRP1,RBBP5,RPA1,RPA3,RRM2,RRS1,SDHAF3,SEC23IP,SFSWAP,SNRNP200,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRSF10,SRSF9,STMN1,STX2,SVIP,SYCP1,TAF11,TAF1B,TAF6L,TERT,TFAM,TGS1,TIMM21,TK1,TLR4,TRIM28,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,TWNK,TXNL4A,UBE2S,UQCC2,VMA21,WNT10B |
| GO_CELL_DIVISION | 0.0e+00 | 0.0e+00 | 1139 | 598 | 91 | AHCTF1,ANAPC1,ANAPC10,ANAPC4,ANLN,ASPM,BIRC5,BLM,BRIP1,BUB1B,BUB3,CCNE1,CCNF,CCP110,CDC20,CDC7,CDCA2,CDCA3,CDCA8,CENPE,CENPF,CENPJ,CENPS,CENPV,CENPX,CETN3,CIT,CKS1B,CKS2,DSN1,E2F8,ECT2,ERCC6L,FAM83D,FBXO5,FIGN,GPSM2,HAUS3,HAUS8,HELLS,INSC,KIF11,KIF14,KIF18B,KIF20A,KIF20B,KIF23,KIF2A,KIF4A,KNL1,KNTC1,LEF1,LIG1,MAD2L1,MCMBP,NCAPD2,NCAPD3,NCAPG,NCAPG2,NDC80,NSUN2,OIP5,PIMREG,PKP4,PLK1,PPP1CC,PRDM15,PRPF40A,PTTG1,REEP4,SEPTIN12,SGO1,SGO2,SKA3,SMC1A,SMC5,SPAG5,SPC25,SPICE1,STMN1,SYCP1,TACC3,TGFB2,TIMELESS,TOP1,TUBA1B,TXNL4A,UBE2S,USP37,VRK1,ZWILCH |
| GO_RIBOSOME_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1139 | 290 | 66 | BMS1,C1QBP,CHD7,DDX31,DDX3X,DDX51,DDX56,DHX30,DHX37,EBNA1BP2,ERI1,ESF1,EXOSC2,EXOSC8,FASTKD2,FBL,FDXACB1,FTSJ3,GEMIN4,HEATR1,HEATR3,ISG20L2,KRR1,LAS1L,LSM6,LTV1,LYAR,MDN1,MPHOSPH10,MRM1,MRM2,MRPL11,MRPS7,MRTO4,MTERF3,MYBBP1A,NOC2L,NOC4L,NOL10,NOL11,NOL6,NOL8,NOM1,NOP16,NOP56,PA2G4,PDCD11,POP5,PWP2,RBFA,RRP1B,RRP8,RRS1,SENP3,SUV39H1,TBL3,URB1,UTP11,UTP20,UTP3,WDR12,WDR18,WDR3,WDR36,WDR74,WDR75 |
| GO_MRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1139 | 503 | 83 | AQR,AURKAIP1,BARD1,C1QBP,CCAR2,CDC5L,CHTOP,CLNS1A,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,DCPS,DHX15,DNAJC8,EFTUD2,ELAVL1,FASTKD5,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2F2,GTF2H3,HNRNPC,HNRNPR,HTATSF1,IWS1,KHDRBS1,LEO1,LSM10,LSM3,LSM6,LSM7,METTL3,NCBP1,NCL,PABPC1L,PDCD11,PNN,PNPT1,POLR2B,POLR2D,POLR2F,POLR2K,PPIH,PPIL1,PPP1R8,PRPF19,PRPF38B,PRPF39,PRPF4,PRPF40A,PRPF4B,PSIP1,RNGTT,RRP1B,SAFB,SAFB2,SF3B4,SFSWAP,SNRNP200,SNRNP40,SNRNP48,SNRNP70,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRRM1,SRSF10,SRSF9,SUGP2,SYNCRIP,TGS1,THOC3,TSEN54,TTF2,TXNL4A,ZC3H13 |
| GO_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 790 | 101 | AHCTF1,AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ATAD5,AURKAIP1,BLM,BMI1,BRCA1,BRD7,BUB1B,BUB3,CARM1,CCNE1,CCNF,CCP110,CDC20,CDC45,CDC7,CENPE,CENPF,CENPJ,CENPV,CEP152,CEP192,CEP41,CEP78,CIT,DBF4,DBF4B,DDX3X,DLGAP5,DONSON,E2F4,E2F8,ECT2,EED,EIF4G1,FAM83D,FBXO5,FEN1,GEN1,GPSM2,GTSE1,HAUS3,HAUS8,KIF11,KIF14,KIF20A,KIF20B,KIF23,KNTC1,LSM10,MACROH2A1,MAD2L1,MDM1,MKI67,MRE11,MYBBP1A,NDC80,ORC1,PAGR1,PAXIP1,PIDD1,PKMYT1,PKP4,PLK1,POC1A,PRKDC,PRPF40A,PSMD5,PSME3,PTTG1,RAD51C,RANBP1,RRM2,RRP8,SIN3A,SLFN11,SMC1A,SMC5,SPAG5,SPICE1,STIL,TACC3,TERF2,TERT,TFDP1,TICRR,TRIP13,TTK,TUBA4A,TUBB4B,TUBG1,TXLNG,USP51,WNT10B,XRCC3 |
| GO_ORGANELLE_FISSION | 0.0e+00 | 0.0e+00 | 1139 | 450 | 78 | ANAPC1,ANAPC4,ANLN,ASPM,AURKAIP1,BIRC5,BRIP1,BUB1B,BUB3,CCNE1,CDC20,CDCA8,CENPE,CENPF,CENPS,CENPX,CEP192,CKS2,DHODH,DLGAP5,DSCC1,DSN1,EME1,FANCA,FANCD2,FBXO5,FIGNL1,GEN1,HASPIN,HIRA,KIF11,KIF14,KIF18B,KIF20B,KIF22,KIF23,KIF2A,KIF4A,KNTC1,MACROH2A1,MAD2L1,MIEF1,MKI67,MLH1,MLH3,MRE11,MSH5,MYBL1,MYBL2,MZT1,NCAPD2,NCAPD3,NCAPG,NDC1,NDC80,OPA1,PKMYT1,PLK1,PTTG1,RAD51C,RAD54B,RANBP1,RMI1,RRS1,SGO1,SGO2,SMC1A,SMC5,SPAG5,SPICE1,SYCP1,TACC3,TRIP13,TTK,TUBG1,UBE2S,WRAP73,XRCC3 |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 1036 | 112 | ACAD9,AHCTF1,ANLN,AP2S1,ARPC1A,ASF1B,ATP23,ATR,BCS1L,CAND1,CDC45,CENPE,CENPF,CENPH,CENPI,CENPJ,CENPL,CENPS,CENPU,CENPV,CENPX,CEP192,CHAF1A,CLNS1A,CLP1,COA1,DHX30,DHX33,DNAAF4,DNAAF5,EIF3B,EIF4G1,FASTKD2,FASTKD3,FBXO5,FKBP4,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2A2,GTF2H3,GTF3C5,H1-3,H2AX,H3C1,HELLS,HIRA,HMGB1,HSPD1,IPO4,KNL1,LYRM7,MACROH2A1,MCM2,MCM5,MCM6,MDN1,MRPL11,MRPS7,MRTO4,MZT1,NCBP1,NDC1,NDUFA12,NDUFAB1,NDUFAF5,NUFIP1,NUP107,OIP5,OTUD6B,PARP1,PLEKHG2,POLE3,POLR2D,PRPF19,PRPF39,PSIP1,PSMD5,PTGES3,PWP2,RPA1,RPA3,RRS1,SDHAF3,SFSWAP,SNRNP200,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRSF10,SRSF9,STMN1,TAF11,TAF1B,TAF6L,TFAM,TGS1,TIMM21,TLR4,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,TXNL4A,UBE2S,UQCC2,VMA21,WNT10B |
| GO_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 840 | 101 | AKT1,APEX1,AQR,AURKAIP1,BARD1,C1QBP,CCAR2,CDC5L,CHTOP,CLNS1A,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,DCPS,DHX15,DNAJC8,DND1,EFTUD2,EIF4G1,ELAVL1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,FASTKD5,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2F2,GTF2H3,HNRNPC,HNRNPR,HTATSF1,IWS1,KHDRBS1,LEO1,LSM10,LSM3,LSM6,LSM7,METTL3,MLH1,MRTO4,NCBP1,NCL,PABPC1L,PDCD11,PNN,PNPT1,POLR2B,POLR2D,POLR2F,POLR2K,PPIH,PPIL1,PPP1R8,PRPF19,PRPF38B,PRPF39,PRPF4,PRPF40A,PRPF4B,PSIP1,PSMD5,PSME3,PUS3,RIDA,RNGTT,RRP1B,SAFB,SAFB2,SERBP1,SF3B4,SFSWAP,SNRNP200,SNRNP40,SNRNP48,SNRNP70,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRRM1,SRSF10,SRSF9,SSB,SUGP2,SYNCRIP,TGS1,THOC3,TRMT10C,TSEN54,TTF2,TXNL4A,UPF2,ZC3H13 |
| GO_DNA_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1139 | 288 | 63 | APEX1,APEX2,ATAD5,AUNIP,BLM,BRCA1,BRIP1,CDC45,CDC7,CENPS,CENPX,EME1,EXO1,FANCB,FEN1,FIGN,FIGNL1,GEN1,H1-3,H2AX,HMGB1,HSPD1,IL7R,INO80E,KLHL15,LEF1,MCM2,MCM5,MCM6,MCM8,MLH1,MLH3,MRE11,MSH5,MSH6,PAGR1,PARP1,PARPBP,PAXIP1,PIF1,POLQ,PRKDC,RAD51C,RAD54B,RMI1,RPA1,RPA3,RTEL1,SMC5,SMC6,SMCHD1,SYCP1,TERF2,TIMELESS,TONSL,TRIP13,UBE2N,UCHL5,USP51,WRAP53,XRCC2,XRCC3,XRCC5 |
| GO_RNA_SPLICING | 0.0e+00 | 0.0e+00 | 1139 | 433 | 74 | AQR,C1QBP,CCAR2,CDC5L,CLNS1A,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,DCPS,DHX15,DNAJC8,EFTUD2,ELAVL1,FAM98B,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2F2,HNRNPC,HNRNPR,HTATSF1,IVNS1ABP,IWS1,KHDRBS1,LSM10,LSM3,LSM6,LSM7,METTL3,MPHOSPH10,NCBP1,NCL,PNN,POLR2B,POLR2D,POLR2F,POLR2K,PPIH,PPIL1,PPP1R8,PRPF19,PRPF38B,PRPF39,PRPF4,PRPF40A,PRPF4B,PSIP1,RRP1B,SF3B4,SFSWAP,SNRNP200,SNRNP40,SNRNP48,SNRNP70,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRRM1,SRSF10,SRSF9,SUGP2,SYNCRIP,TGS1,THOC3,TSEN54,TTF2,TXNL4A,ZC3H13 |
| GO_NUCLEAR_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 263 | 60 | ANAPC1,ANAPC4,BRIP1,BUB1B,BUB3,CCNE1,CDC20,CDCA8,CENPE,CENPF,CENPS,CENPX,DDX12P,DLGAP5,DSCC1,DSN1,ECT2,EME1,ESCO2,FAM83D,FANCD2,FBXO5,FEN1,GEN1,HASPIN,HIRA,KIF14,KIF18B,KIF22,KIF23,KIF4A,KNL1,MACROH2A1,MAD2L1,MCMBP,MLH1,MLH3,MRE11,NCAPD2,NCAPD3,NCAPG,NDC1,NDC80,PLK1,PTTG1,RAD51C,RMI1,RRS1,SGO1,SGO2,SMC1A,SMC5,SPAG5,SPICE1,SYCP1,TACC3,TRIP13,TTK,TUBG1,XRCC3 |
| GO_MITOCHONDRIAL_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 1139 | 165 | 49 | AARS2,AURKAIP1,C1QBP,CDK5RAP1,DARS2,ELAC2,FASTKD2,FASTKD3,FASTKD5,GFM1,LARS2,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF1,MTERF3,PNPT1,PPARGC1B,PTCD3,SARS2,TEFM,TFAM,TRMT10C,TSFM,TWNK,UQCC2 |
| GO_DNA_CONFORMATION_CHANGE | 0.0e+00 | 0.0e+00 | 1139 | 322 | 61 | ASF1B,BLM,BRIP1,CDAN1,CDC45,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,CHD7,DDX12P,DDX3X,DNA2,DSCC1,ERCC6L,GINS1,GTF2F2,GTF2H3,H1-3,H2AX,H3C1,HELLS,HIRA,HMGB1,IPO4,KNL1,MACROH2A1,MCM2,MCM5,MCM6,MCM8,MRE11,MTERF1,NCAPD2,NCAPD3,NCAPG,NCAPG2,NOC2L,OIP5,PARP1,PIF1,POLE3,POLQ,RAD54B,RFC2,RFC3,RFC4,RFC5,RPA1,RTEL1,SMCHD1,SSBP1,SYCP1,TOP1,TOP3B,TWNK,XRCC5 |
| GO_RRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 221 | 52 | BMS1,CHD7,DDX51,DDX56,DHX37,EBNA1BP2,ERI1,ESF1,EXOSC2,EXOSC8,FBL,FDXACB1,FTSJ3,GEMIN4,HEATR1,ISG20L2,KRR1,LAS1L,LSM6,LYAR,MDN1,MPHOSPH10,MRM1,MRM2,MRTO4,NOC4L,NOL10,NOL11,NOL6,NOL8,NOP56,PA2G4,PDCD11,POP5,PWP2,RBFA,RRP1B,RRP8,RRS1,SENP3,SUV39H1,TBL3,URB1,UTP11,UTP20,UTP3,WDR12,WDR18,WDR3,WDR36,WDR74,WDR75 |
| GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 664 | 83 | AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ATAD5,AURKAIP1,BLM,BRCA1,BRD7,BUB1B,BUB3,CARM1,CCNE1,CCP110,CDC20,CDC45,CDC7,CENPE,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,CKS1B,CKS2,DBF4B,DCLRE1B,DDIAS,DDX3X,DLGAP5,DONSON,E2F4,E2F8,EIF4E,EIF4G1,EME1,FBXO5,GEN1,GPSM2,GTSE1,HAUS3,HAUS8,KIF11,KIF14,KIF20B,KNTC1,LSM10,MACROH2A1,MAD2L1,MKI67,MRE11,NDC80,ORC1,PIDD1,PKMYT1,PLK1,PNPT1,PRKDC,PSMD5,PSME3,PTTG1,RAD51C,RANBP1,RPA3,SIN3A,SLFN11,SMC1A,SMC5,TACC3,TERT,TFDP1,TICRR,TRIP13,TTK,TUBA4A,TUBB4B,TUBG1,WNT10B,XRCC3,ZWILCH |
| GO_PEPTIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 736 | 87 | AARS2,AKT1,AURKAIP1,C12orf65,C1QBP,CAPRIN2,CDK5RAP1,CHAC2,DARS2,DDX3X,DHFR,DHX29,DHX33,DNAJC24,EEF2K,EIF1AX,EIF2B1,EIF2B3,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,FASTKD2,FASTKD3,GEMIN5,GFM1,GGCT,GGT2,GUF1,HNRNPR,KHDRBS1,LARS2,MARS2,METAP1,METTL17,METTL3,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF3,NARS2,NCBP1,NCL,PA2G4,PER2,POLR2D,PTCD3,RARS1,RIDA,RPL39L,RPS6KA1,SARS2,SELENOT,SRBD1,SYNCRIP,TCOF1,THBS1,TRMT10C,TSFM,TYMS,UQCC2,YTHDF1 |
| GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS | 0.0e+00 | 0.0e+00 | 1139 | 345 | 61 | AQR,C1QBP,CDC5L,CLNS1A,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,DCPS,DHX15,DNAJC8,EFTUD2,ELAVL1,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTF2F2,HNRNPC,HNRNPR,HTATSF1,KHDRBS1,LSM3,LSM6,LSM7,METTL3,MPHOSPH10,NCBP1,NCL,PNN,POLR2B,POLR2D,POLR2F,POLR2K,PPIH,PPIL1,PRPF19,PRPF39,PRPF4,PRPF40A,PRPF4B,PSIP1,SF3B4,SFSWAP,SNRNP200,SNRNP40,SNRNP48,SNRNP70,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRRM1,SRSF10,SRSF9,SYNCRIP,TGS1,TXNL4A |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1859 | 140 | AARS2,ADCY3,AFMID,AKT1,ASNSD1,ATP5PF,AURKAIP1,B3GALNT1,B3GALNT2,C12orf65,C1GALT1,C1QBP,CAD,CAPRIN2,CDK5RAP1,CHAC2,DARS2,DDX3X,DHFR,DHODH,DHX29,DHX33,DLAT,DNAJC24,DTYMK,DUT,EEF2K,EIF1AX,EIF2B1,EIF2B3,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,ENOPH1,FABP5,FAM20B,FASTKD2,FASTKD3,FKTN,FLAD1,FUT1,FUT10,FXN,GALNT14,GART,GEMIN5,GFM1,GGCT,GGT2,GOT2,GUF1,HACD3,HNRNPR,HPRT1,HS3ST2,HS3ST3A1,IL1RAP,IMPDH1,KHDRBS1,LARS2,MARS2,METAP1,METTL17,METTL3,MMACHC,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF3,MTHFD2L,NARS2,NCBP1,NCL,NME1,NR4A2,PA2G4,PAICS,PARP1,PER2,POGLUT2,POLR2D,PPAT,PRPS1,PRPS2,PSPH,PTCD3,PTDSS1,RARS1,RIDA,RPL39L,RPS6KA1,RXYLT1,SARS2,SELENOT,SLC1A3,SLC25A13,SRBD1,SRM,STARD7,SVIP,SYNCRIP,TCOF1,TGFB2,THBS1,TK1,TLR4,TRMT10C,TSFM,TYMS,UBE2G2,UMPS,UQCC2,YTHDF1,ZDHHC6 |
| GO_CHROMATIN_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 795 | 89 | ASF1B,BEND3,BMI1,BRCA1,BRD7,CARM1,CBX2,CDAN1,CDC45,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,CHD7,CHTOP,CRTC2,DNMT1,DNMT3B,EED,EPOP,FBL,GATA2,GTF3C4,H1-3,H2AX,H2AZ1,H2AZ2,H3C1,HASPIN,HDAC2,HELLS,HIRA,HIRIP3,HMGB1,HMGN1,HNRNPC,ING5,INO80E,IPO4,IWS1,KNL1,LEF1,LEO1,MACROH2A1,MAP3K7,MBD3,MCM2,MKI67,MTF2,MYB,NOC2L,NUDT5,OIP5,PABPC1L,PAGR1,PAXBP1,PAXIP1,PER2,PHB,POLE3,PTMA,RBBP5,RRP8,SAFB,SIN3A,SMCHD1,SRCAP,SUPT16H,SUV39H1,SUV39H2,SYCP1,TAF5,TAF6L,TBL1X,TDG,TOP1,TRIM28,UBE2N,UHRF1,USP51,UTP3,VRK1,WDR5,WDR82,YEATS4 |
| GO_MITOTIC_NUCLEAR_DIVISION | 0.0e+00 | 0.0e+00 | 1139 | 264 | 54 | ANAPC1,ANAPC4,ANLN,AURKAIP1,BIRC5,BUB1B,BUB3,CDC20,CDCA8,CENPE,CENPF,CEP192,DLGAP5,DSCC1,DSN1,FBXO5,GEN1,HASPIN,HIRA,KIF11,KIF14,KIF18B,KIF20B,KIF22,KIF23,KIF2A,KIF4A,KNTC1,MACROH2A1,MAD2L1,MKI67,MYBL2,MZT1,NCAPD2,NCAPD3,NCAPG,NDC80,PKMYT1,PLK1,PTTG1,RANBP1,RRS1,SGO1,SMC1A,SMC5,SPAG5,SPICE1,TACC3,TRIP13,TTK,TUBG1,UBE2S,WRAP73,XRCC3 |
| GO_MITOCHONDRIAL_TRANSLATION | 0.0e+00 | 0.0e+00 | 1139 | 137 | 41 | AARS2,AURKAIP1,C1QBP,CDK5RAP1,DARS2,FASTKD2,FASTKD3,GFM1,LARS2,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF3,PTCD3,SARS2,TRMT10C,TSFM,UQCC2 |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 752 | 84 | ASPM,AUNIP,BIRC5,BRCA1,CCNF,CCP110,CDC20,CENPE,CENPJ,CEP152,CEP192,CETN3,CFAP20,CFAP46,CLUAP1,DLGAP5,DNAAF4,DNAAF5,E2F4,EPHA3,FBXO5,FIGN,FIGNL1,FKBP4,GAS2L3,GEN1,GPSM2,GTSE1,HAUS3,HAUS8,IFT172,KIF11,KIF14,KIF15,KIF18B,KIF20A,KIF20B,KIF22,KIF23,KIF24,KIF2A,KIF4A,KLC2,MAD2L1,MDM1,MLH1,MYBL2,MZT1,NDC80,OPA1,PCLAF,PLK1,POC1A,RANBP1,RASGRP1,RHOT2,SASS6,SGO1,SKA3,SMC1A,SPAG5,SPC25,SPICE1,SSX2IP,STIL,STMN1,TACC3,TCTEX1D2,TEKT4,TERF2,TMEM201,TTK,TUBA1B,TUBA4A,TUBB4B,TUBB6,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,WDR34,WRAP73,XRCC2,XRCC3 |
| GO_AMIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 876 | 90 | AARS2,AKT1,ASNSD1,AURKAIP1,C12orf65,C1QBP,CAPRIN2,CDK5RAP1,CHAC2,DARS2,DDX3X,DHFR,DHX29,DHX33,DLAT,DNAJC24,EEF2K,EIF1AX,EIF2B1,EIF2B3,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,FASTKD2,FASTKD3,GART,GEMIN5,GFM1,GGCT,GGT2,GUF1,HNRNPR,KHDRBS1,LARS2,MARS2,METAP1,METTL17,METTL3,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF3,NARS2,NCBP1,NCL,PA2G4,PER2,POLR2D,PTCD3,RARS1,RIDA,RPL39L,RPS6KA1,SARS2,SELENOT,SRBD1,SYNCRIP,TCOF1,THBS1,TRMT10C,TSFM,TYMS,UQCC2,YTHDF1 |
| GO_PEPTIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 879 | 90 | AARS2,AKT1,AURKAIP1,C12orf65,C1QBP,CAPRIN2,CDK5RAP1,CHAC2,DARS2,DDX3X,DHFR,DHX29,DHX33,DNAJC24,EEF2K,EIF1AX,EIF2B1,EIF2B3,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,FASTKD2,FASTKD3,GEMIN5,GFM1,GGCT,GGT2,GUF1,HNRNPR,KHDRBS1,LARS2,MARS2,METAP1,METTL17,METTL3,MMACHC,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF3,NARS2,NCBP1,NCL,PA2G4,PER2,POLR2D,PTCD3,RARS1,RIDA,RPL39L,RPS6KA1,SARS2,SELENOT,SPCS1,SRBD1,SYNCRIP,TCOF1,THBS1,THOP1,TRMT10C,TSFM,TYMS,UQCC2,YTHDF1 |
| GO_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 189 | 45 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CDCA8,CENPE,CENPF,DDX12P,DLGAP5,DSCC1,DSN1,ESCO2,FBXO5,FEN1,GEN1,HASPIN,HIRA,KIF14,KIF18B,KIF22,KIF23,KIF4A,MACROH2A1,MAD2L1,MCMBP,MRE11,NCAPD2,NCAPD3,NCAPG,NDC80,PLK1,PTTG1,RAD51C,RRS1,SGO1,SGO2,SMC1A,SMC5,SPAG5,TACC3,TRIP13,TTK,TUBG1,XRCC3 |
| GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 482 | 67 | AKT1,ANAPC1,ANAPC10,ANAPC4,ANLN,APEX1,ATAD5,BLM,BRCA1,BRD7,BUB1B,BUB3,CARM1,CCNE1,CCP110,CDC20,CDC45,CDC7,CENPE,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,DBF4,DBF4B,DDX3X,DLGAP5,DONSON,E2F4,E2F8,EIF4G1,FAM83D,FBXO5,GEN1,GTSE1,HAUS3,HAUS8,KIF14,KNTC1,LSM10,MACROH2A1,MAD2L1,MRE11,NDC80,ORC1,PAGR1,PAXIP1,PIDD1,PLK1,PRKDC,PSMD5,PSME3,RAD51C,SIN3A,SLFN11,TERT,TFDP1,TICRR,TRIP13,TTK,TUBA4A,TUBB4B,TUBG1,WNT10B,XRCC3 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1988 | 139 | AKT1,APEX1,ATAD5,ATR,BLM,BRCA1,BRD7,C1QBP,CACYBP,CAND1,CAPRIN2,CARM1,CCAR2,CCNE1,CDC5L,CDC7,CDK5RAP1,CHD7,CHUK,CRTC2,DBF4,DBF4B,DDX3X,DHX29,DHX33,DLGAP5,DLX1,DNA2,DSCC1,E2F4,E2F8,EDRF1,EGR3,ELAVL1,ELL3,ERG,ERLIN1,ESR2,FASTKD2,FASTKD3,GATA2,GTF2A2,GTF2F2,GUF1,H1-3,H2AZ1,HDAC2,HEATR1,HMGB1,HMGN1,HNRNPAB,HOXA2,ICE1,ING5,IPPK,IRF3,KHDRBS1,KLRK1,LEF1,LEO1,LRP5L,MED20,MED4,METTL3,MIXL1,MRPL12,MRPS27,MTF2,MYB,MYBL1,MYBL2,MYCBP,NCL,NCOA7,NFATC3,NKRF,NOL11,NR4A2,NUFIP1,NUP85,ONECUT2,PABPC1L,PAGR1,PARP1,PAXBP1,PAXIP1,PBX2,PER2,PFKM,PHB,POLR2D,PPARGC1B,PRDM15,PRKDC,PTGES3,PTPN2,RFC2,RFC3,RFC4,RFC5,RFXAP,RPS6KA1,RRP1B,SAFB,SIN3A,SIX1,SLC45A3,SOX7,SP4,SRCAP,ST18,SUB1,SUPT16H,SVIP,TAF11,TAF6L,TBL1X,TERT,TFAM,TFDP1,TGFB2,THBS1,TLR4,TRIM28,TRMT10C,UBE2L3,UHRF1,UQCC2,VEZF1,VHL,WDR5,WDR75,WNT10B,WRAP53,XRCC5,YEATS4,YTHDF1,ZBTB24,ZNF691 |
| GO_DOUBLE_STRAND_BREAK_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 251 | 49 | ATP23,AUNIP,BARD1,BLM,BRCA1,BRIP1,CDC45,CDC7,DCLRE1B,DNA2,EME1,ESCO2,FANCB,FEN1,FIGN,FIGNL1,GEN1,H2AX,KLHL15,MCM2,MCM5,MCM6,MCM8,MLH1,MRE11,PARP1,PARPBP,PAXIP1,POLA1,POLQ,PRKDC,PRPF19,RAD51C,RAD54B,RMI1,RPA1,RPA3,RTEL1,SMC5,SMCHD1,TIMELESS,TONSL,TRIP13,UBE2N,USP51,WRAP53,XRCC2,XRCC3,XRCC5 |
| GO_CELL_CYCLE_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1139 | 64 | 29 | ATAD5,CDC45,CDC7,DBF4,DBF4B,DNA2,DONSON,E2F8,FBXO5,FEN1,GINS1,LIG1,MCM2,MCM5,MCM6,POLA1,POLA2,POLD1,POLE2,POLE3,PRIM1,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,RTEL1,TERF2 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1870 | 132 | AKT1,APEX1,ATAD5,ATR,BLM,BRCA1,BRD7,CAND1,CAPRIN2,CARM1,CCAR2,CCNE1,CDC5L,CHD7,CHUK,CRTC2,DDX3X,DHX33,DLGAP5,DLX1,DSCC1,E2F4,E2F8,EDRF1,EGR3,ELL3,ERG,ERLIN1,ESR2,FANCB,GATA2,GTF2A2,GTF2F2,H1-3,H2AX,H2AZ1,HDAC2,HEATR1,HMGB1,HMGN1,HNRNPAB,HNRNPR,HOXA2,ICE1,ING5,IPPK,IRF3,LEF1,LEO1,LRP5L,MED20,MED4,METTL3,MIXL1,MLH1,MRE11,MRPL12,MTF2,MYB,MYBL1,MYBL2,MYCBP,NCBP1,NCL,NCOA7,NFATC3,NKRF,NOL11,NR4A2,NUFIP1,NUP85,ONECUT2,PABPC1L,PAGR1,PARP1,PAXBP1,PAXIP1,PBX2,PER2,PFKM,PHB,PNPT1,PPARGC1B,PRDM15,PRKDC,PRPF19,PTGES3,RFC2,RFC3,RFC4,RFC5,RFXAP,RIDA,RPS6KA1,RRP1B,RTEL1,SAFB,SF3B4,SIN3A,SIX1,SMCHD1,SNRNP70,SOX7,SP4,SRCAP,ST18,SUB1,SUPT16H,TAF11,TAF6L,TBL1X,TERT,TFAM,TFDP1,TGFB2,TIMELESS,TLR4,TNFRSF1B,TRIM28,UBE2L3,UBE2N,UHRF1,VEZF1,VHL,WDR5,WDR75,WNT10B,WRAP53,XRCC5,YEATS4,ZBTB24,ZNF691 |
| GO_METHYLATION | 0.0e+00 | 0.0e+00 | 1139 | 366 | 56 | BEND3,BRCA1,CARM1,CHTOP,CIAPIN1,DNMT1,DNMT3B,EED,EEF1AKMT1,EEF2KMT,FAM86C1,FAM98A,FAM98B,FBL,FDXACB1,FTSJ3,GATAD2A,GCSH,GTPBP3,H1-3,HNMT,ICMT,IWS1,MACROH2A1,MBD3,METTL17,METTL2B,METTL3,MRM1,MRM2,MTF2,MYB,NDUFAF5,NSUN2,NSUN5P2,PAGR1,PARP1,PAXBP1,PAXIP1,PRDM15,PRMT3,RBBP5,RRP8,SETD9,SMYD4,SNRPD3,SUV39H1,SUV39H2,TGS1,TRIM28,TRMT10C,TRMT11,TYMS,WDR5,WDR82,ZC3H13 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1470 | 112 | APEX1,AUNIP,BARD1,BEND3,BIRC5,BLM,BMI1,BRCA1,BRD7,C1QBP,CBX2,CCAR2,CCNE1,CDC45,CENPF,CENPJ,DLX1,DMBX1,DNAJA3,DND1,DNMT1,DNMT3B,E2F4,E2F8,EED,ELAVL1,ESR2,FANCB,GATA2,GATAD2A,GCFC2,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,HNRNPC,HOXA2,IRF3,KHDRBS1,KLHL15,LEF1,LYAR,MACROH2A1,MAGEA1,MBD3,MLH1,MSH6,MTERF3,MTF2,MXD3,MYB,MYBBP1A,NACC1,NFATC3,NKRF,NOC2L,NR4A2,ORC2,PA2G4,PARP1,PARPBP,PAXBP1,PER2,PHB,PHF6,PIF1,PLK1,POLE3,POLQ,PPARGC1B,PRDM15,PSPC1,PTPN2,RRP8,RTEL1,SFSWAP,SIN3A,SIX1,SLIRP,SMCHD1,SOX7,SRSF10,SRSF9,SUV39H1,SUV39H2,SYNCRIP,TBL1X,TDG,TERF2,TERT,THAP11,THAP7,TIMELESS,TONSL,TRIM28,UHRF1,VHL,WNT10B,XRCC5,ZBTB24,ZBTB6,ZNF174,ZNF177,ZNF239,ZNF354B,ZNF488,ZNF530,ZNF589,ZNF691,ZNF692 |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 553 | 67 | ASPM,AUNIP,BIRC5,BRCA1,CCNF,CCP110,CDC20,CENPE,CENPJ,CEP152,CEP192,CETN3,CFAP46,DNAAF4,DNAAF5,E2F4,EPHA3,FBXO5,FIGN,FIGNL1,FKBP4,GAS2L3,GEN1,GPSM2,HAUS3,HAUS8,IFT172,KIF11,KIF18B,KIF20A,KIF23,KIF24,KIF2A,KIF4A,MAD2L1,MDM1,MLH1,MYBL2,MZT1,NDC80,PCLAF,PLK1,POC1A,RANBP1,SASS6,SGO1,SKA3,SMC1A,SPAG5,SPC25,SPICE1,SSX2IP,STIL,STMN1,TACC3,TTK,TUBA1B,TUBA4A,TUBB4B,TUBB6,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,WRAP73,XRCC2,XRCC3 |
| GO_MITOTIC_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 151 | 38 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CDCA8,CENPE,CENPF,DLGAP5,DSCC1,DSN1,FBXO5,GEN1,HASPIN,HIRA,KIF14,KIF18B,KIF22,KIF23,KIF4A,MACROH2A1,MAD2L1,NCAPD2,NCAPD3,NCAPG,NDC80,PLK1,PTTG1,RRS1,SGO1,SMC1A,SMC5,SPAG5,TACC3,TRIP13,TTK,TUBG1,XRCC3 |
| GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1146 | 97 | AARS2,AKT1,ASNSD1,AURKAIP1,C12orf65,C1QBP,CAPRIN2,CDK5RAP1,CHAC2,DARS2,DDX3X,DHFR,DHX29,DHX33,DLAT,DNAJC24,EEF2K,EIF1AX,EIF2B1,EIF2B3,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,FASTKD2,FASTKD3,GART,GEMIN5,GFM1,GGCT,GGT2,GUF1,HNRNPR,KHDRBS1,LARS2,MARS2,METAP1,METTL17,METTL3,MMACHC,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,MTERF3,MTHFD2L,NARS2,NCBP1,NCL,NEU3,PA2G4,PER2,POLR2D,PTCD3,RARS1,RIDA,RPL39L,RPS6KA1,SARS2,SELENOT,SLC19A1,SLC5A6,SPCS1,SRBD1,SYNCRIP,TCOF1,THBS1,THOP1,TRMT10C,TSFM,TYMS,UQCC2,YTHDF1 |
| GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 299 | 49 | AKT1,APEX1,BRD7,CARM1,CCNE1,CDC45,CDC7,CDKN3,CUL2,DBF4,DDX3X,DHFR,E2F4,E2F8,EIF4E,EIF4G1,FAM83D,FBXO5,GTSE1,KHDRBS1,KIF14,LSM10,MCM10,MCM2,MCM5,MCM6,MCM8,ORC1,ORC2,ORC5,PAGR1,PIDD1,POLA1,POLA2,POLE2,POLE3,PPAT,PRIM1,PRKDC,PSME3,RPA1,RPA3,RRM2,SKP2,SLFN11,TERT,TFDP1,TYMS,USP37 |
| GO_ORGANELLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 835 | 80 | ANLN,ASPM,ATG3,BIRC5,BRCA1,C1QBP,CCP110,CDC20,CDKN3,CENPE,CENPF,CENPH,CENPJ,CENPS,CENPX,CEP152,CEP192,CEP41,CEP78,CFAP20,CFAP46,CLUAP1,DDX3X,DHX30,DNAAF4,DNAAF5,E2F4,FARP2,FASTKD2,FBXO5,GPSM2,HAUS3,HAUS8,HYLS1,IFT172,IL1RAP,KIF11,KIF23,KIF24,KIF2A,KIF4A,KNL1,LSM3,MDM1,MDN1,MLH1,MRPL11,MRPS7,MRTO4,MTERF3,MYBL2,MYPN,MZT1,NEB,ONECUT2,PGM5,PLK1,POC1A,PWP2,RAB8A,RPGRIP1L,RRS1,SASS6,SCLT1,SMC1A,SPAG5,SPICE1,SSX2IP,STIL,TCTEX1D2,TEKT4,TMEM237,TUBA4A,TUBB4B,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,WDR34,WRAP73 |
| GO_NUCLEAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1139 | 347 | 52 | AKT1,BARD1,CHTOP,CPSF3,CPSF4,CSE1L,DDX19A,ECT2,EIF4E,EIF4ENIF1,FBXO22,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTSE1,HEATR3,IPO4,IWS1,KHDRBS1,KPNA3,LSG1,LTV1,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,PPP1CC,PSIP1,RANBP3,RRS1,SNRPD1,SNRPD3,SNRPF,SNRPG,SRRM1,SRSF9,SSB,STRADB,THOC3,TRIM28,UPF2,XPO6,XPO7 |
| GO_RECOMBINATIONAL_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 136 | 35 | AUNIP,BLM,BRCA1,CDC45,CDC7,FANCB,FEN1,FIGN,FIGNL1,GEN1,H2AX,KLHL15,MCM2,MCM5,MCM6,MCM8,MRE11,PARP1,PARPBP,POLQ,RAD51C,RAD54B,RMI1,RPA1,RPA3,RTEL1,SMC5,SMCHD1,TIMELESS,TONSL,UBE2N,USP51,WRAP53,XRCC2,XRCC3 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 297 | 48 | AKT1,ANAPC4,APEX1,ATAD5,BRCA1,CARM1,CCNE1,CDC45,CDC7,CENPJ,CENPV,CIT,DBF4,DBF4B,DDX3X,DLGAP5,E2F4,E2F8,ECT2,EIF4G1,FAM83D,FBXO5,FEN1,GEN1,GPSM2,GTSE1,KIF14,KIF20B,KIF23,LSM10,MACROH2A1,MAD2L1,MYBBP1A,NDC80,PAGR1,PIDD1,PKP4,POC1A,RAD51C,RANBP1,RRP8,SIN3A,SMC5,SPAG5,TERT,TFDP1,WNT10B,XRCC3 |
| GO_MEIOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 245 | 44 | ASPM,BRIP1,BUB1B,BUB3,CCNE1,CDC20,CENPS,CENPX,CKS2,EME1,EXO1,FANCA,FANCD2,FBXO5,FIGNL1,H2AX,METTL3,MLH1,MLH3,MRE11,MSH5,MSH6,MYBL1,NCAPD2,NCAPD3,NDC1,NSUN2,PLK1,PTTG1,RAD51C,RAD54B,RMI1,RPA1,SGO1,SGO2,SMC1A,SYCP1,TRIP13,TTK,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,XRCC2 |
| GO_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 347 | 51 | ANAPC1,ANAPC4,ATR,BRCA1,BRD7,BUB1B,BUB3,CDC20,CDC45,CENPE,CENPF,CENPV,CHTOP,DLGAP5,DNMT1,DNMT3B,EED,FBXO5,FEN1,GATA2,GEN1,H1-3,HIRA,HNRNPC,IWS1,MACROH2A1,MAD2L1,MCM2,MKI67,MRE11,MTF2,MYB,NDC80,NOC2L,PARP1,PAXBP1,PAXIP1,PIF1,PLK1,PTTG1,RTEL1,SIN3A,SMC5,TACC3,TERF2,TRIM28,TRIP13,TTK,UBE2N,XRCC3,XRCC5 |
| GO_DNA_GEOMETRIC_CHANGE | 0.0e+00 | 0.0e+00 | 1139 | 114 | 32 | BLM,BRIP1,CDC45,CHD7,DDX12P,DDX3X,DNA2,DSCC1,ERCC6L,GINS1,GTF2F2,GTF2H3,HMGB1,MCM2,MCM5,MCM6,MCM8,MRE11,MTERF1,PARP1,PIF1,POLQ,RAD54B,RFC2,RFC3,RFC4,RFC5,RPA1,RTEL1,SSBP1,TWNK,XRCC5 |
| GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | 0.0e+00 | 0.0e+00 | 1139 | 297 | 47 | APEX1,APEX2,ASTE1,ATAD5,CPSF3,CPSF4,CSTF2,CSTF3,DCLRE1B,DCPS,DNA2,ELAC2,EME1,ERI1,EXO1,EXO5,EXOSC2,EXOSC8,FEN1,GEN1,GTF2H3,HMGB1,ISG20L2,LAS1L,MRE11,NCBP1,NTHL1,PARP1,PNPT1,POLD1,POLR3K,POP5,PPP1R8,REXO5,RFC2,RFC3,RFC4,RFC5,RIDA,RNASEH1,RPA1,RPA3,RPP14,RRS1,TREX2,TSEN54,UTP20 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1673 | 114 | APEX1,ATR,BEND3,BIRC5,BLM,BMI1,BRCA1,BRD7,C1QBP,CAPRIN2,CBX2,CCAR2,CCNE1,CDAN1,CDC45,CENPF,CENPJ,DDX3X,DHFR,DLX1,DMBX1,DNAJA3,DNMT1,DNMT3B,DONSON,E2F4,E2F8,EED,EIF4E,EIF4ENIF1,EIF4G1,ERLIN1,ESR2,FBXO5,GATA2,GATAD2A,GCFC2,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,HNRNPC,HNRNPR,HOXA2,IRF3,KHDRBS1,LEF1,LYAR,MACROH2A1,MAGEA1,MBD3,METTL3,MRPL13,MTERF3,MTF2,MXD3,MYB,MYBBP1A,NACC1,NCL,NFATC3,NKRF,NOC2L,NR4A2,ORC2,PA2G4,PARP1,PAXBP1,PER2,PHB,PHF6,PIF1,PLK1,POLE3,PPARGC1B,PRDM15,PSPC1,PTPN2,RIDA,RRP8,SIN3A,SIX1,SLFN11,SMCHD1,SOX7,SUV39H1,SUV39H2,SYNCRIP,TBL1X,TDG,TERF2,THAP11,THAP7,TIMELESS,TONSL,TRIM28,TYMS,UHRF1,VHL,WNT10B,XRCC5,ZBTB24,ZBTB6,ZNF174,ZNF177,ZNF239,ZNF354B,ZNF488,ZNF530,ZNF589,ZNF691,ZNF692 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 637 | 67 | ATR,AURKAIP1,BARD1,BLM,BMI1,BRCA1,BRD7,BRIP1,BUB1B,BUB3,CARM1,CCAR2,CCNF,CDC20,CDC45,CDC5L,CDC7,CDK5RAP1,CDKN3,CENPF,DCLRE1B,DDIAS,DNA2,DONSON,E2F4,E2F8,EED,EME1,FBXO5,GEN1,GTSE1,H2AX,KIF20B,KNTC1,MACROH2A1,MAD2L1,MDM1,MRE11,MYBBP1A,NDC80,NSUN2,ORC1,PIDD1,PLK1,PNPT1,PPM1G,PPP2R3B,PRKDC,PRPF19,PSMD5,PSME3,PTTG1,RRM2,RRP8,SLFN11,STRADB,TERF2,TFDP1,TGFB2,THBS1,TICRR,TIMELESS,TRIP13,TTK,WNT10B,XRCC3,ZWILCH |
| GO_TRANSLATIONAL_ELONGATION | 0.0e+00 | 0.0e+00 | 1139 | 135 | 33 | AURKAIP1,DNAJC24,EEF2K,GFM1,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,PTCD3,SELENOT,TSFM |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 391 | 52 | AKT1,ANAPC4,APEX1,ATAD5,BRCA1,CARM1,CCNE1,CDC45,CDC7,CENPJ,CENPV,CIT,CKS1B,CKS2,DBF4,DBF4B,DDX3X,DLGAP5,E2F4,E2F8,ECT2,EIF4E,EIF4G1,FAM83D,FBXO5,FEN1,GEN1,GPSM2,GTSE1,KIF14,KIF20B,KIF23,LSM10,MACROH2A1,MAD2L1,MYBBP1A,NDC80,PAGR1,PIDD1,PKP4,POC1A,RAD51C,RANBP1,RRP8,SIN3A,SMC5,SPAG5,TERT,TFDP1,TGFB2,WNT10B,XRCC3 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1710 | 114 | AKT1,APEX1,BLM,BRCA1,BRD7,CAND1,CAPRIN2,CARM1,CCAR2,CCNE1,CDC5L,CHD7,CHUK,CRTC2,DDX3X,DHX33,DLGAP5,DLX1,E2F4,E2F8,EDRF1,EGR3,ELL3,ERG,ERLIN1,ESR2,GATA2,GTF2A2,GTF2F2,H1-3,H2AZ1,HDAC2,HEATR1,HMGB1,HMGN1,HNRNPAB,HNRNPR,HOXA2,ICE1,ING5,IPPK,IRF3,LEF1,LEO1,LRP5L,MED20,MED4,METTL3,MIXL1,MRPL12,MTF2,MYB,MYBL1,MYBL2,MYCBP,NCBP1,NCL,NCOA7,NFATC3,NKRF,NOL11,NR4A2,NUFIP1,NUP85,ONECUT2,PABPC1L,PAGR1,PARP1,PAXBP1,PAXIP1,PBX2,PER2,PFKM,PHB,PNPT1,PPARGC1B,PRDM15,PRKDC,PRPF19,RFXAP,RIDA,RPS6KA1,RRP1B,SAFB,SF3B4,SIN3A,SIX1,SNRNP70,SOX7,SP4,SRCAP,ST18,SUB1,SUPT16H,TAF11,TAF6L,TBL1X,TERT,TFAM,TFDP1,TGFB2,TLR4,TNFRSF1B,TRIM28,UBE2L3,UHRF1,VEZF1,VHL,WDR5,WDR75,WNT10B,YEATS4,ZBTB24,ZNF691 |
| GO_MITOCHONDRIAL_TRANSLATIONAL_TERMINATION | 0.0e+00 | 0.0e+00 | 1139 | 89 | 28 | AURKAIP1,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,PTCD3 |
| GO_TELOMERE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 175 | 36 | APEX1,ATR,BLM,CCNE1,DCLRE1B,DNA2,EXO1,FEN1,H3C1,HNRNPC,MRE11,PARP1,PIF1,POLA1,POLA2,POLD1,POLE2,POLE3,PRIM1,PRKDC,PTGES3,RAD51C,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,RTEL1,SMC5,SMC6,TERF2,TERT,WRAP53,XRCC3,XRCC5 |
| GO_TRANSLATIONAL_TERMINATION | 0.0e+00 | 0.0e+00 | 1139 | 105 | 29 | AURKAIP1,C12orf65,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,PTCD3 |
| GO_PEPTIDYL_LYSINE_MODIFICATION | 0.0e+00 | 0.0e+00 | 1139 | 397 | 51 | BEND3,BRCA1,BRD7,CRTC2,DNMT1,DNMT3B,EED,EEF1AKMT1,EEF2KMT,GATA2,GCSH,GLRX5,GTF3C4,H1-3,HDAC2,ING5,IWS1,KIAA1586,LEF1,MACROH2A1,MAP3K7,MBD3,MTF2,MYB,NDC1,NDUFAB1,NOC2L,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,P3H3,PAGR1,PAXIP1,POLE3,RBBP5,SAE1,SENP3,SIN3A,SRCAP,SUV39H1,SUV39H2,TAF5,TAF6L,TRIM28,WDR5,WDR82,YEATS4 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 1267 | 93 | AKT1,ANAPC1,ANAPC4,ANLN,ARPC1A,ATG3,ATR,AURKAIP1,BRCA1,BRD7,BUB1B,BUB3,CCNF,CCP110,CDC20,CDC45,CENPE,CENPF,CENPJ,CENPV,CHTOP,CIT,DHODH,DLGAP5,DNMT1,DNMT3B,ECT2,EED,EPHA3,FBXO5,FEN1,FKBP4,FXN,GATA2,GEN1,GPSM2,H1-3,HIRA,HNRNPC,IL1RAP,IWS1,KIF11,KIF20B,KNTC1,MACROH2A1,MAD2L1,MCM2,MDM1,MIEF1,MKI67,MRE11,MTF2,MYB,NDC80,NEB,NOC2L,OPA1,PARP1,PAXBP1,PAXIP1,PIF1,PKMYT1,PLEKHG2,PLK1,POC1A,PRELID1,PTTG1,RANBP1,RHOT2,RTEL1,SAE1,SH3BP1,SIN3A,SKA3,SMC1A,SMC5,SPAG5,SPICE1,STIL,STMN1,TACC3,TCTEX1D2,TERF2,TFDP1,TMEM33,TRIM28,TRIP13,TTK,UBE2L3,UBE2N,WRAP73,XRCC3,XRCC5 |
| GO_CELL_CYCLE_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1139 | 217 | 38 | ATR,BLM,BRCA1,BRIP1,BUB1B,BUB3,CARM1,CCAR2,CDC20,CDC45,CDC5L,CENPF,DCLRE1B,DNA2,DONSON,E2F4,E2F8,EME1,GEN1,GTSE1,H2AX,KNTC1,MAD2L1,MRE11,NDC80,NSUN2,ORC1,PIDD1,PLK1,PRKDC,PRPF19,TFDP1,TICRR,TIMELESS,TRIP13,TTK,XRCC3,ZWILCH |
| GO_MACROMOLECULE_METHYLATION | 0.0e+00 | 0.0e+00 | 1139 | 306 | 44 | BEND3,BRCA1,CARM1,CHTOP,DNMT1,DNMT3B,EED,EEF1AKMT1,EEF2KMT,FAM98A,FAM98B,FBL,FDXACB1,FTSJ3,GATAD2A,GTPBP3,H1-3,ICMT,IWS1,MACROH2A1,MBD3,METTL2B,METTL3,MRM1,MRM2,MTF2,MYB,NSUN2,PAGR1,PARP1,PAXBP1,PAXIP1,PRMT3,RBBP5,SNRPD3,SUV39H1,SUV39H2,TGS1,TRIM28,TRMT10C,TRMT11,WDR5,WDR82,ZC3H13 |
| GO_TRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 183 | 35 | AARS2,ADAT1,ANKRD16,CDK5RAP1,CLP1,CPSF4,CSTF2,CTU2,DARS2,ELAC2,ELP6,EXOSC2,EXOSC8,FAM98B,GTPBP3,LARS2,LSM6,MARS2,METTL2B,NARS2,NSUN2,OSGEP,POLR3K,POP5,PTCD1,PUS3,RARS1,RPP14,SARS2,SSB,TPRKB,TRMT10C,TRMT11,TSEN54,TYW1 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1280 | 91 | APEX1,BEND3,BIRC5,BMI1,BRCA1,BRD7,C1QBP,CBX2,CCAR2,CCNE1,CDC45,CENPF,CENPJ,DLX1,DMBX1,DNAJA3,DNMT1,DNMT3B,E2F4,E2F8,EED,ESR2,GATA2,GATAD2A,GCFC2,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,HOXA2,IRF3,KHDRBS1,LEF1,LYAR,MACROH2A1,MAGEA1,MBD3,MTERF3,MTF2,MXD3,MYB,MYBBP1A,NACC1,NFATC3,NKRF,NOC2L,NR4A2,ORC2,PA2G4,PARP1,PAXBP1,PER2,PHB,PHF6,PLK1,POLE3,PPARGC1B,PRDM15,PSPC1,PTPN2,RRP8,SIN3A,SIX1,SMCHD1,SOX7,SUV39H1,SUV39H2,TBL1X,TDG,THAP11,THAP7,TIMELESS,TONSL,TRIM28,UHRF1,VHL,WNT10B,XRCC5,ZBTB24,ZBTB6,ZNF174,ZNF177,ZNF239,ZNF354B,ZNF488,ZNF530,ZNF589,ZNF691,ZNF692 |
| GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 193 | 35 | ATR,CLNS1A,CLP1,DHX30,EIF3B,FASTKD2,GCFC2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,MDN1,MRPL11,MRPS7,MRTO4,NCBP1,NUFIP1,POLR2D,PRPF19,PRPF39,PSIP1,PTGES3,PWP2,RRS1,SFSWAP,SNRNP200,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRSF10,SRSF9,TGS1,TXNL4A |
| GO_SPINDLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 169 | 33 | ASPM,AUNIP,BIRC5,CDC20,CENPE,CEP192,FBXO5,GPSM2,HAUS3,HAUS8,KIF11,KIF23,KIF2A,KIF4A,MLH1,MYBL2,MZT1,NDC80,PLK1,POC1A,SMC1A,SPAG5,SPC25,SPICE1,STIL,STMN1,TACC3,TTK,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,WRAP73 |
| GO_NUCLEAR_EXPORT | 0.0e+00 | 0.0e+00 | 1139 | 195 | 35 | BARD1,CHTOP,CPSF3,CPSF4,CSE1L,DDX19A,EIF4E,EIF4ENIF1,GTSE1,IWS1,KHDRBS1,LSG1,LTV1,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,RANBP3,RRS1,SRRM1,SRSF9,SSB,STRADB,THOC3,UPF2,XPO6,XPO7 |
| GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1139 | 267 | 40 | AKT1,ATAD5,ATR,BARD1,BLM,BRCA1,BRD7,BRIP1,CARM1,DNA2,E2F4,E2F8,ELL3,EXO1,GTSE1,HDAC2,ING5,MBD3,MRE11,MYBBP1A,NOC2L,PAXIP1,PIDD1,RFC2,RFC3,RFC4,RFC5,RMI1,RPA1,RPA3,RRP8,RRS1,SETD9,SSRP1,SUPT16H,TAF11,TAF5,TFDP1,TMEM109,USP10 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 1139 | 1258 | 89 | AKT1,ATR,BEND3,BRCA1,BRD7,CAD,CAPRIN2,CARM1,CDC7,CEP41,CFAP20,CHCHD4,CHUK,CIT,CRTC2,DNAJC24,DNMT1,DNMT3B,EED,EEF1AKMT1,EEF2KMT,EIF4G1,EPHA3,FKBP4,GATA2,GCSH,GLRX5,GTF3C4,H1-3,HASPIN,HDAC2,HPF1,ING5,IWS1,KIAA1586,LEF1,MACROH2A1,MAP3K7,MBD3,METAP1,METAP2,MTF2,MYB,NCAPG2,NCOA7,NDC1,NDUFAB1,NDUFAF5,NOC2L,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,P3H3,PAGR1,PARP1,PAXIP1,PLK1,POGLUT2,POLE3,PPIH,PPIL1,PRDX3,PRKDC,PRMT3,PTPN2,RBBP5,SAE1,SENP3,SIN3A,SRCAP,SUV39H1,SUV39H2,TAF5,TAF6L,TMX3,TOP1,TRIM28,TTK,UBE2G2,VKORC1L1,VRK1,WDR5,WDR82,YEATS4,ZDHHC6 |
| GO_MEIOTIC_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 187 | 34 | ASPM,BRIP1,BUB1B,CCNE1,CDC20,CENPS,CENPX,CKS2,EME1,FANCA,FANCD2,FBXO5,FIGNL1,MLH1,MLH3,MRE11,MSH5,MSH6,MYBL1,NCAPD2,NCAPD3,NDC1,NSUN2,PLK1,PTTG1,RAD51C,RAD54B,RMI1,SGO1,SGO2,SYCP1,TRIP13,TTK,TUBG1 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 1139 | 1741 | 108 | ACOX2,AKT1,AP2S1,ARL5A,ATG3,ATP5PF,BARD1,CHCHD4,CHTOP,CLUAP1,CNIH3,CPSF3,CPSF4,CSE1L,CTSC,DDX19A,ECT2,EIF4E,EIF4ENIF1,FBXO22,FUT10,GATA2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,GTSE1,HEATR3,HEATR5A,HSPD1,ICE1,ICMT,IER3IP1,IFT172,IMMP1L,IPO4,IWS1,KHDRBS1,KIF14,KIF20B,KIF23,KIF4A,KPNA3,LSG1,LTV1,MIEF1,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,OPA1,POLR2D,PPP1CC,PPP6R3,PSIP1,RAB8A,RANBP1,RANBP3,RASGRP1,RHOT2,RRS1,SAE1,SEC23IP,SGTA,SNRPD1,SNRPD3,SNRPF,SNRPG,SPAG5,SPCS1,SRRM1,SRSF10,SRSF9,SSB,SSX2IP,STRADB,STX2,SVIP,TCTEX1D2,TERF2,TEX261,THOC3,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TMEM201,TOMM22,TOMM5,TOMM70,TRIM28,TUBA1B,UBE2G2,UBE2L3,UPF2,VPS54,WDR34,XPO6,XPO7,ZDHHC6 |
| GO_CHROMOSOME_SEPARATION | 0.0e+00 | 0.0e+00 | 1139 | 89 | 25 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CENPE,CENPF,CENPS,CENPX,DLGAP5,EME1,FBXO5,GEN1,MAD2L1,MLH1,NCAPD2,NCAPD3,NDC80,PLK1,PTTG1,RMI1,TACC3,TRIP13,TTK,XRCC3 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 0.0e+00 | 1139 | 1114 | 82 | AKT1,ANAPC1,ANAPC10,ANAPC4,ATG3,BARD1,BMI1,BRCA1,CAND1,CCNF,CCP110,CDC20,CDCA3,CENPS,CENPX,COPS9,CTU2,CUL2,DCAF16,DCUN1D4,DCUN1D5,EPOP,FANCL,FBXL6,FBXO22,FBXO45,FBXO5,FEM1A,G2E3,HSPBP1,INO80E,IVNS1ABP,KIAA1586,KLHL15,KLHL17,LEO1,LRR1,MAD2L1,MAP3K7,MED20,MKRN3,NDC1,NEURL4,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OTUD6B,PAXIP1,PER2,PLK1,PRKDC,PRMT3,PRPF19,PSMD5,PSME3,RNF121,RNF26,SAE1,SENP3,SKP2,SPRTN,THOP1,TRAF7,TRIM28,TRIM41,UBE2G2,UBE2L3,UBE2N,UBE2NL,UBE2S,UBE3C,UCHL5,UHRF1,USP10,USP18,USP37,USP51,VHL |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1962 | 115 | AARS2,ACAD9,ACOX2,ADCY3,ADIPOR2,AFMID,AKT1,ALDH1B1,APOBEC3B,ASNSD1,ATP5PF,BRCA1,CA1,CAD,COX11,CRTC2,DARS2,DCTPP1,DHFR,DHODH,DHRS7B,DLAT,DTYMK,DUT,ECHDC1,ENOPH1,ENOSF1,ENTPD2,ENTPD6,ERH,ERLIN1,FABP5,FDXR,FLAD1,FUT1,FUT10,FXN,GART,GCSH,GGT2,GK5,GLRX5,GNPNAT1,GOT2,GPD2,HACD3,HNMT,HPRT1,IDH3A,IMPDH1,IPPK,KHK,L2HGDH,LARS2,LBR,LDHB,MARS2,MCAT,MMACHC,MTHFD2L,NARS2,NDC1,NDUFAB1,NEIL2,NME1,NTHL1,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,OSBPL3,PAICS,PARG,PARP1,PDE4A,PDE7A,PDSS1,PER2,PFKM,PGM5,PPAT,PRPS1,PRPS2,PSMD5,PSME3,PSPH,PTGES3,PTPN2,RARS1,RIDA,RPE,RRM2,SARS2,SDHAF3,SDHB,SFXN1,SLC16A9,SLC19A1,SLC1A3,SLC25A13,SLC25A17,SLC45A3,SLC5A6,TDG,TK1,TYMS,UMPS,VKORC1L1,WDR5,XYLB |
| GO_TELOMERE_MAINTENANCE_VIA_SEMI_CONSERVATIVE_REPLICATION | 0.0e+00 | 0.0e+00 | 1139 | 27 | 16 | DNA2,FEN1,POLA1,POLA2,POLD1,POLE2,POLE3,PRIM1,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,RTEL1,TERF2 |
| GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 287 | 40 | ASF1B,CAND1,CDC45,CENPE,CENPF,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,GTF2A2,GTF2H3,GTF3C5,H1-3,H2AX,H3C1,HELLS,HIRA,HMGB1,IPO4,KNL1,MACROH2A1,MCM2,MCM5,MCM6,OIP5,PARP1,POLE3,PTMA,RPA1,RPA3,SRCAP,SUPT16H,TAF11,TAF1B,TAF6L,WNT10B |
| GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 353 | 44 | AKT1,ATAD5,ATR,AUNIP,BLM,BRCA1,DSCC1,FANCB,FIGN,FIGNL1,H1-3,H2AX,HMGB1,HNRNPC,IL7R,KLHL15,MBD3,MLH1,MRE11,MSH6,PARG,PARP1,PARPBP,PAXIP1,PIF1,POLQ,PRKDC,PTGES3,RFC2,RFC3,RFC4,RFC5,RTEL1,SMCHD1,TERF2,TFDP1,TICRR,TIMELESS,TRIM28,UBE2N,USP51,WDR18,WRAP53,XRCC5 |
| GO_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1139 | 229 | 36 | AHCTF1,ATR,CETN3,CHTOP,CPSF3,CPSF4,DDX19A,EIF4E,EXOSC2,FBL,IWS1,KHDRBS1,LTV1,MRPL18,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,PNPT1,POLR2D,RRS1,SRRM1,SRSF9,SSB,TERF2,THOC3,UPF2,WRAP53,XPO7 |
| GO_DNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 190 | 33 | ATR,CENPF,DSCC1,HNRNPC,LIG1,MRE11,PCLAF,PHB,PIF1,POLA1,POLA2,POLD1,POLE2,POLE3,POLG2,POLQ,PTGES3,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,SPRTN,SYCP1,TERF2,TERT,TFDP1,TK1,TYMS,USP10,WRAP53,XRCC5 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1139 | 1930 | 112 | ACOX2,AKT1,ANLN,AP2S1,ARL5A,ATG3,ATP1B3,ATR,BARD1,BUB3,CARM1,CCNE1,CEP192,CHCHD4,CHTOP,CLUAP1,CPSF3,CPSF4,CSE1L,DDX19A,DDX3X,DNAJA3,ECT2,EIF4E,EPHA3,ESCO2,EXOSC2,FAM83D,FUT10,GPSM2,GTSE1,HASPIN,HEATR3,HSPD1,ICE1,ICMT,IFT172,IMMP1L,IPO4,IWS1,KIF20B,KNL1,KPNA3,LTV1,MACROH2A1,MCM8,MIEF1,MPP5,MZT1,NCBP1,NDC1,NDC80,NOL6,NOL8,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,PARP1,PLK1,POLR1A,POLR2D,PRPF19,RAB8A,RABEP1,RANBP3,RPA1,RRS1,SAE1,SEC23IP,SGTA,SIN3A,SIX1,SPAG5,SPCS1,SRRM1,SRSF9,SSB,SSX2IP,STIL,STRADB,STX2,SVIP,SYNGAP1,TCTEX1D2,TERF2,TERT,TFDP1,THOC3,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,TRIM28,TTK,UBE2G2,UBE2L3,UPF2,WDR34,WRAP53,XPO6,XPO7,XRCC5,ZDHHC6 |
| GO_REPRODUCTION | 0.0e+00 | 0.0e+00 | 1139 | 1457 | 94 | ADCY3,ADIPOR2,AKT1,ASF1B,ASPM,BRIP1,BUB1B,BUB3,C1QBP,CAD,CBX2,CCNE1,CCNF,CDC20,CENPI,CENPS,CENPX,CHD7,CKS2,DDX3X,DHODH,DND1,E2F8,ELL3,EME1,EXO1,FANCA,FANCC,FANCD2,FANCL,FBXO5,FIGNL1,FKBP4,FUT10,GATA2,GGT2,GMCL1,GOT2,H2AX,HDAC2,KHDRBS1,KNL1,LEF1,MCM8,METTL3,MLH1,MLH3,MRE11,MSH5,MSH6,MYBL1,MYCBP,NCAPD2,NCAPD3,NDC1,NSUN2,NUP107,PABPC1L,PAFAH1B2,PAFAH1B3,PLK1,POC1A,POLR1B,PPAT,PRDX3,PRKDC,PTTG1,RAD51C,RAD54B,RMI1,RPA1,RPL39L,SAFB2,SEPTIN12,SGO1,SGO2,SLIRP,SMC1A,SPIN4,STX2,SYCP1,TEKT4,TGFB2,TRIM28,TRIP13,TSGA10,TTK,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,UBAP2L,UMPS,XRCC2 |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 528 | 53 | ACAD9,AKT1,ATG3,ATP23,ATP5PF,BCS1L,CCAR2,CHCHD4,CLUH,COA1,CYCS,DHODH,DNA2,DNAJA3,FASTKD3,FXN,GGCT,HSPD1,IMMP1L,LETM1,LYRM7,MIEF1,MTERF1,NDUFA12,NDUFAB1,NDUFAF5,OPA1,PARP1,PHB,PIF1,PNPT1,POLG2,PRDX3,PRELID1,RHOT2,SAE1,SDHAF3,SLIRP,SSBP1,TERT,TFAM,TFDP1,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,TWNK,UBE2L3,UQCC2 |
| GO_COVALENT_CHROMATIN_MODIFICATION | 0.0e+00 | 0.0e+00 | 1139 | 473 | 50 | BEND3,BMI1,BRCA1,BRD7,CARM1,CHTOP,CRTC2,DNMT1,DNMT3B,EED,EPOP,FBL,GATA2,GTF3C4,H1-3,HASPIN,HDAC2,HELLS,ING5,IWS1,LEF1,LEO1,MACROH2A1,MAP3K7,MBD3,MTF2,MYB,NOC2L,PAGR1,PAXBP1,PAXIP1,PER2,PHB,POLE3,RBBP5,SIN3A,SRCAP,SUV39H1,SUV39H2,TAF5,TAF6L,TBL1X,TRIM28,UBE2N,UHRF1,USP51,VRK1,WDR5,WDR82,YEATS4 |
| GO_ESTABLISHMENT_OF_RNA_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1139 | 196 | 33 | AHCTF1,ATR,CETN3,CHTOP,CPSF3,CPSF4,DDX19A,EIF4E,IWS1,KHDRBS1,LTV1,MRPL18,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,PNPT1,POLR2D,RRS1,SRRM1,SRSF9,SSB,TERF2,THOC3,UPF2,XPO7 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 0.0e+00 | 1139 | 912 | 71 | AKT1,ANAPC1,ANAPC10,ANAPC4,ATG3,BARD1,BMI1,BRCA1,CAND1,CCNF,CDC20,CDCA3,CENPS,CENPX,COPS9,CTU2,CUL2,DCAF16,DCUN1D4,DCUN1D5,FANCL,FBXL6,FBXO22,FBXO45,FBXO5,FEM1A,G2E3,HSPBP1,IVNS1ABP,KIAA1586,KLHL15,KLHL17,LEO1,LRR1,MAD2L1,MED20,MKRN3,NDC1,NEURL4,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PAXIP1,PER2,PLK1,PRKDC,PRMT3,PRPF19,PSMD5,PSME3,RNF121,RNF26,SAE1,SKP2,SPRTN,THOP1,TRAF7,TRIM28,TRIM41,UBE2G2,UBE2L3,UBE2N,UBE2NL,UBE2S,UBE3C,UHRF1,VHL |
| GO_REGULATION_OF_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 103 | 25 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CENPE,CENPF,DLGAP5,ECT2,FBXO5,FEN1,GEN1,MACROH2A1,MAD2L1,MKI67,NDC80,PLK1,PTTG1,SMC5,SMC6,SPAG5,TACC3,TRIP13,TTK,XRCC3 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION | 0.0e+00 | 0.0e+00 | 1139 | 75 | 22 | CD3EAP,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,GTF2H3,LSM10,MTERF1,NCBP1,POLR1A,POLR1B,POLR1C,POLR2F,POLR2K,POLR3K,SNRPD3,SNRPF,SNRPG,TAF1B,TTF2,TWISTNB |
| GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 219 | 34 | AURKAIP1,C12orf65,KIF18B,KIF24,KIF2A,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,PTCD3,SH3BP1,STMN1 |
| GO_TRNA_PROCESSING | 0.0e+00 | 0.0e+00 | 1139 | 128 | 27 | AARS2,ADAT1,ANKRD16,CDK5RAP1,CLP1,CPSF4,CSTF2,CTU2,ELAC2,ELP6,FAM98B,GTPBP3,LSM6,METTL2B,NSUN2,OSGEP,POLR3K,POP5,PTCD1,PUS3,RPP14,SSB,TPRKB,TRMT10C,TRMT11,TSEN54,TYW1 |
| GO_NCRNA_TRANSCRIPTION | 0.0e+00 | 0.0e+00 | 1139 | 107 | 25 | CD3EAP,ELL3,GTF2A2,GTF2F2,GTF3C4,GTF3C5,ICE1,INTS2,INTS8,INTS9,IPPK,MACROH2A1,NCBP1,NCL,NOL11,POLR1B,POLR2B,POLR2D,POLR2F,POLR2K,SNAPC4,TAF11,TAF1B,TAF5,TCOF1 |
| GO_REGULATION_OF_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1139 | 107 | 25 | ATAD5,ATR,BLM,CACYBP,CDAN1,CDC7,DBF4,DBF4B,DNA2,DONSON,DSCC1,E2F8,ESCO2,FBXO5,ORC5,RFC2,RFC3,RFC4,RFC5,SLFN11,TERF2,TICRR,TIMELESS,USP37,WDR18 |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1180 | 81 | AKT1,ANAPC1,ANAPC10,ANAPC4,AP2S1,APEX1,ARMC8,BUB1B,BUB3,CCAR2,CCNF,CDC20,CTSC,CUL2,DCPS,DDI2,DNA2,DNAAF4,DND1,EIF4G1,ELAVL1,ERI1,ERLIN1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,FBXL6,FBXO22,FBXO45,FBXO5,FEN1,FOXRED2,HMGB1,HNRNPC,HNRNPR,HSPBP1,KIF14,KLHL15,LSM3,LSM6,LSM7,MAD2L1,METTL3,MLH1,MRTO4,NCBP1,PBK,PLK1,PNPT1,POLR2D,PPP1R8,PRPF19,PSMD5,PSME3,PTTG1,RIDA,RNASEH1,RNF121,SERBP1,SGTA,SKP2,SLIRP,SSB,SVIP,SYNCRIP,TBL1X,TNFRSF1B,UBE2G2,UBE2L3,UBE2S,UBE3C,UCHL5,UHRF1,UPF2,UQCC2,USP10,USP18,USP37,USP51,WNT10B |
| GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | 0.0e+00 | 0.0e+00 | 1139 | 861 | 67 | AKT1,APEX1,C1QBP,CAPRIN2,CDK5RAP1,CLP1,DDX3X,DHFR,DHX29,DNAJC24,DND1,EIF2B1,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,EXOSC2,EXOSC8,FASTKD1,FASTKD2,FASTKD3,GEMIN5,GUF1,H3C1,HNRNPC,HNRNPR,KHDRBS1,METAP1,METTL3,MRPL13,MRPS27,NCBP1,NCL,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PA2G4,PER2,POLR2B,POLR2D,POLR2F,POLR2K,PRKRA,PSMD5,PSME3,PTCD3,RIDA,RPS6KA1,SELENOT,SERBP1,SYNCRIP,TCOF1,TERT,THBS1,TNFRSF1B,TRMT10C,TSFM,TYMS,UQCC2,YTHDF1 |
| GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 146 | 28 | BRCA1,BUB1B,BUB3,CDC20,CENPF,DNMT1,DNMT3B,FBXO5,GEN1,H1-3,HNRNPC,MACROH2A1,MAD2L1,MCM2,MTF2,NDC80,NOC2L,PARP1,PIF1,PLK1,PTTG1,RTEL1,SIN3A,TERF2,TRIP13,TTK,XRCC3,XRCC5 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1139 | 751 | 61 | AKT1,ATAD5,ATR,AUNIP,BRCA1,CCAR2,DDIAS,DHFR,EIF4G1,ELL3,FANCB,FBXO5,FIGN,FIGNL1,FKBP4,FKTN,H2AX,HACD3,HMGB1,KLHL15,LETM1,MAGEA3,MAP3K7,NCOA7,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PARG,PARP1,PARPBP,PAXIP1,PBK,PNPT1,POLQ,PRKDC,PTGES3,PTPN2,RASGRP1,RPA1,RPA3,RTEL1,SGTA,SMCHD1,SVIP,TERF2,TERT,TGFB2,TIMELESS,TLR4,TMEM33,TRIM28,UBE2G2,UBE2N,USP51,WRAP53 |
| GO_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1139 | 286 | 37 | ATR,BIRC5,CHTOP,CLUAP1,CPSF3,CPSF4,DDX19A,EIF4E,FKBP4,HASPIN,IFT172,IWS1,LTV1,MZT1,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,RAB8A,RRS1,SRRM1,SRSF9,SSB,SSX2IP,TCTEX1D2,TERF2,THOC3,UPF2,WDR34 |
| GO_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 271 | 36 | ATAD5,BLM,BRCA1,CCP110,CDC7,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,CIT,DBF4B,DONSON,FBXO5,GTSE1,HAUS3,HAUS8,KHDRBS1,KIF14,MACROH2A1,MRE11,ORC1,PAXIP1,PKMYT1,PLK1,PSMD5,PSME3,RAD51C,SIN3A,SKP2,TICRR,TUBA4A,TUBB4B,TUBG1,WNT10B |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 1335 | 85 | ANLN,ARAP3,ARPC1A,ASPM,AUNIP,BIRC5,BRCA1,CCNF,CCP110,CDC20,CENPE,CENPJ,CEP152,CEP192,CETN3,CFAP46,CIT,DNAAF4,DNAAF5,E2F4,ECT2,EPHA3,FAM171A1,FARP2,FBXO5,FIGN,FIGNL1,FKBP4,GAS2L3,GEN1,GPSM2,HAUS3,HAUS8,IFT172,KIF11,KIF18B,KIF20A,KIF23,KIF24,KIF2A,KIF4A,KLHL17,MAD2L1,MDM1,MLH1,MYBL2,MYPN,MZT1,NDC80,NEB,PCLAF,PGM5,PLEKHG2,PLK1,POC1A,PPARGC1B,PRPF40A,RANBP1,SASS6,SGO1,SH3BP1,SHROOM2,SKA3,SMC1A,SPAG5,SPC25,SPICE1,SSX2IP,STIL,STMN1,TACC3,TTK,TUBA1B,TUBA4A,TUBB4B,TUBB6,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5,VPS54,WRAP73,XRCC2,XRCC3,YEATS4 |
| GO_DNA_REPLICATION_INITIATION | 0.0e+00 | 0.0e+00 | 1139 | 37 | 16 | CCNE1,CDC45,MCM10,MCM2,MCM5,MCM6,ORC1,ORC2,ORC5,POLA1,POLA2,POLE2,POLE3,PRIM1,TICRR,WDR18 |
| GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 214 | 32 | ATAD5,BLM,BRCA1,CCP110,CDC7,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,DBF4B,DONSON,FBXO5,GTSE1,HAUS3,HAUS8,KIF14,MACROH2A1,MRE11,ORC1,PAXIP1,PLK1,PSMD5,PSME3,RAD51C,SIN3A,TICRR,TUBA4A,TUBB4B,TUBG1,WNT10B |
| GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 80 | 21 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CENPE,CENPF,DLGAP5,FBXO5,FEN1,GEN1,MACROH2A1,MAD2L1,NDC80,PLK1,PTTG1,SMC5,TACC3,TRIP13,TTK,XRCC3 |
| GO_RNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 0.0e+00 | 1139 | 136 | 26 | CHTOP,CPSF3,CPSF4,DDX19A,EIF4E,IWS1,KHDRBS1,LTV1,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,RRS1,SRRM1,SRSF9,SSB,THOC3,UPF2 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1410 | 87 | AKT1,ANAPC1,ANAPC10,ANAPC4,AP2S1,APEX1,ARMC8,BARD1,BUB1B,BUB3,CCAR2,CCNF,CDC20,CTRL,CTSC,CTSE,CUL2,DCPS,DDI2,DNA2,DNAAF4,DND1,EIF4G1,ELAVL1,ERI1,ERLIN1,EXOSC2,EXOSC8,FAM83D,FASTKD1,FASTKD3,FBXL6,FBXO22,FBXO45,FBXO5,FEN1,FOXRED2,HMGB1,HNRNPC,HNRNPR,HSPBP1,KIF14,KLHL15,LSM3,LSM6,LSM7,MAD2L1,METTL3,MLH1,MRTO4,NCBP1,PBK,PHB,PLK1,PNPT1,POLR2D,PPP1R8,PRPF19,PSMD5,PSME3,PTTG1,RIDA,RNASEH1,RNF121,SERBP1,SGTA,SKP2,SLIRP,SNRNP70,SSB,SVIP,SYNCRIP,TBL1X,TNFRSF1B,UBE2G2,UBE2L3,UBE2S,UBE3C,UCHL5,UHRF1,UPF2,UQCC2,USP10,USP18,USP37,USP51,WNT10B |
| GO_MITOTIC_CELL_CYCLE_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1139 | 165 | 28 | BLM,BRCA1,BUB1B,BUB3,CARM1,CDC20,CENPF,DCLRE1B,DONSON,E2F4,E2F8,EME1,GEN1,GTSE1,KNTC1,MAD2L1,MRE11,NDC80,ORC1,PIDD1,PLK1,PRKDC,TFDP1,TICRR,TRIP13,TTK,XRCC3,ZWILCH |
| GO_MITOCHONDRIAL_RNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 47 | 17 | AARS2,CDK5RAP1,DARS2,ELAC2,FASTKD1,FASTKD5,MRPL12,MTERF1,MTERF3,PNPT1,PPARGC1B,SARS2,SLIRP,TEFM,TFAM,TRMT10C,TWNK |
| GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | 0.0e+00 | 0.0e+00 | 1139 | 240 | 33 | AHCTF1,CETN3,CHTOP,CPSF3,CPSF4,DDX19A,EIF4E,IWS1,KHDRBS1,LTV1,MRPL18,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,PNPT1,POLR2D,RRS1,SLC25A17,SRRM1,SRSF9,SSB,TERF2,THOC3,UPF2,XPO7 |
| GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 0.0e+00 | 1139 | 181 | 29 | AKT1,ATAD5,ATR,BARD1,BLM,BRCA1,BRD7,BRIP1,DNA2,ELL3,EXO1,HDAC2,ING5,MBD3,MRE11,NOC2L,RFC2,RFC3,RFC4,RFC5,RMI1,RPA1,RPA3,RRS1,SETD9,SSRP1,SUPT16H,TAF11,TAF5 |
| GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 0.0e+00 | 0.0e+00 | 1139 | 433 | 44 | APEX1,ATR,BARD1,BLM,CCNE1,DCLRE1B,DNA2,EXO1,FEN1,GATA2,HNRNPC,IL20RA,MDM1,MRE11,PARP1,PFKM,PIF1,POLA1,POLA2,POLD1,POLE2,POLE3,PPARGC1B,PRIM1,PRKDC,PTGES3,RAD51C,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,RTEL1,SMC5,SMC6,TERF2,TERT,TLR4,VPS54,WDR36,WRAP53,XRCC3,XRCC5 |
| GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION | 0.0e+00 | 0.0e+00 | 1139 | 48 | 17 | BLM,CDC7,DBF4,DBF4B,DONSON,DSCC1,E2F8,FBXO5,RFC2,RFC3,RFC4,RFC5,SLFN11,TERF2,TICRR,TIMELESS,WDR18 |
| GO_MITOTIC_SPINDLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 107 | 23 | BIRC5,CDC20,CENPE,CEP192,GPSM2,KIF11,KIF23,KIF2A,KIF4A,MYBL2,MZT1,NDC80,PLK1,POC1A,SMC1A,SPC25,SPICE1,STIL,STMN1,TACC3,TTK,TUBG1,WRAP73 |
| GO_SPINDLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 107 | 23 | ASPM,BIRC5,CDC20,CEP192,FBXO5,GPSM2,HAUS3,HAUS8,KIF11,KIF23,KIF2A,KIF4A,MLH1,MYBL2,MZT1,PLK1,SMC1A,SPAG5,SPICE1,TUBGCP3,TUBGCP4,TUBGCP5,WRAP73 |
| GO_REGULATION_OF_NUCLEAR_DIVISION | 0.0e+00 | 0.0e+00 | 1139 | 187 | 29 | ANAPC1,ANAPC4,ANLN,AURKAIP1,BUB1B,BUB3,CDC20,CENPE,CENPF,DLGAP5,FBXO5,GEN1,KIF11,KIF20B,KNTC1,MACROH2A1,MAD2L1,MKI67,NDC80,PKMYT1,PLK1,PTTG1,RANBP1,SMC1A,SMC5,TACC3,TRIP13,TTK,XRCC3 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 0.0e+00 | 0.0e+00 | 1139 | 111 | 23 | CCAR2,CD3EAP,ELL3,GTF2F2,GTF2H3,HMGN1,HTATSF1,IWS1,LEO1,NCBP1,POLR1A,POLR1B,POLR1C,POLR2B,POLR2D,POLR2F,POLR2K,SSRP1,SUPT16H,TAF1B,TEFM,TSFM,TWISTNB |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1139 | 860 | 63 | BEND3,BMI1,C1QBP,CBX2,CCNE1,DLX1,DMBX1,DNAJA3,DNMT1,DNMT3B,E2F4,E2F8,EED,ESR2,GATA2,GATAD2A,GCFC2,H1-3,HDAC2,HMGB1,HOXA2,IRF3,KHDRBS1,LEF1,LYAR,MACROH2A1,MAGEA1,MBD3,MTF2,MXD3,MYB,NFATC3,NOC2L,NR4A2,ORC2,PARP1,PAXBP1,PER2,PHB,PHF6,PLK1,PTPN2,SIN3A,SIX1,SUV39H1,SUV39H2,TBL1X,TDG,THAP11,TIMELESS,TRIM28,UHRF1,VHL,WNT10B,ZBTB24,ZBTB6,ZNF174,ZNF177,ZNF239,ZNF354B,ZNF589,ZNF691,ZNF692 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 356 | 39 | AURKAIP1,BLM,BMI1,BRCA1,BRD7,BUB1B,BUB3,CARM1,CCNF,CDC20,CDC7,CENPF,DONSON,E2F4,E2F8,EED,FBXO5,GEN1,GTSE1,MACROH2A1,MAD2L1,MDM1,MRE11,NDC80,ORC1,PIDD1,PLK1,PRKDC,PSMD5,PSME3,PTTG1,RRM2,SLFN11,TERF2,TFDP1,TICRR,TRIP13,TTK,XRCC3 |
| GO_RNA_3_END_PROCESSING | 0.0e+00 | 0.0e+00 | 1139 | 150 | 26 | BARD1,CHTOP,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,ELAC2,ERI1,EXOSC2,EXOSC8,FBL,INTS2,INTS8,LEO1,NCBP1,PABPC1L,PNPT1,POLR2D,POLR3K,PTCD1,SRRM1,SRSF9,SSB,THOC3,TRMT10C |
| GO_PROTEIN_METHYLATION | 0.0e+00 | 0.0e+00 | 1139 | 178 | 28 | BEND3,BRCA1,CARM1,CHTOP,DNMT1,DNMT3B,EED,EEF1AKMT1,EEF2KMT,FAM98A,FAM98B,FBL,H1-3,ICMT,IWS1,MACROH2A1,MTF2,MYB,PAGR1,PAXBP1,PAXIP1,PRMT3,RBBP5,SNRPD3,SUV39H1,SUV39H2,WDR5,WDR82 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 1139 | 1559 | 90 | ACOX2,AJAP1,AKT1,ATAD5,ATR,AUNIP,BRCA1,C1QBP,CCAR2,CHUK,CTSC,DDIAS,DHFR,EIF4G1,ELL3,FANCA,FANCB,FANCD2,FBXO5,FEM1A,FFAR4,FIGN,FIGNL1,FKBP4,FKTN,GGT2,H2AX,HACD3,HMGB1,HSPD1,IL12RB1,IRF3,KLHL15,KLRK1,LETM1,MACROH2A1,MAGEA3,MAP3K7,METTL3,NCOA7,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PARG,PARP1,PARPBP,PAXIP1,PBK,PNPT1,POLQ,POLR3B,POLR3G,PRKDC,PSMD5,PSME3,PSPC1,PTGES3,PTPN2,PVR,RASGRP1,RNF26,RPA1,RPA3,RTEL1,SGTA,SHPK,SIN3A,SMCHD1,SVIP,TERF2,TERT,TGFB2,THBS1,TIMELESS,TLR4,TMEM33,TNFRSF1B,TRIM28,UBE2G2,UBE2N,USP18,USP51,WRAP53,XRCC5 |
| GO_REGULATION_OF_CHROMOSOME_SEPARATION | 0.0e+00 | 0.0e+00 | 1139 | 62 | 18 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CENPE,CENPF,DLGAP5,FBXO5,GEN1,MAD2L1,NDC80,PLK1,PTTG1,TACC3,TRIP13,TTK,XRCC3 |
| GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 0.0e+00 | 0.0e+00 | 1139 | 586 | 50 | BEND3,BMI1,BRCA1,CD3EAP,CDC45,CLP1,DND1,DNMT1,DNMT3B,EED,EIF4G1,ELAVL1,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,MACROH2A1,MBD3,METTL3,MTF2,MYBBP1A,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PABPC1L,POLE3,POLR1A,POLR1B,POLR1C,POLR2B,POLR2D,POLR2F,POLR2K,PRKRA,RRP8,SIN3A,SMCHD1,SUV39H1,TAF1B,TDG,TERT,TRIM28,TWISTNB |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 0.0e+00 | 1139 | 1151 | 74 | ACOX2,AKT1,AP2S1,ARL5A,ATG3,BARD1,CHCHD4,CHTOP,CLUAP1,CPSF3,CPSF4,CSE1L,DDX19A,ECT2,EIF4E,FUT10,GTSE1,HEATR3,HSPD1,ICE1,ICMT,IFT172,IMMP1L,IPO4,IWS1,KIF20B,KPNA3,LTV1,MIEF1,NCBP1,NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,RAB8A,RANBP3,RRS1,SAE1,SEC23IP,SGTA,SPCS1,SRRM1,SRSF9,SSB,SSX2IP,STRADB,STX2,SVIP,TCTEX1D2,TERF2,THOC3,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,TRIM28,UBE2G2,UBE2L3,UPF2,WDR34,XPO6,XPO7,ZDHHC6 |
| GO_CELLULAR_NITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 587 | 50 | AFMID,AKT1,APEX1,APOBEC3B,DCPS,DCTPP1,DNA2,DND1,DUT,EIF4G1,ELAVL1,ENTPD2,ENTPD6,ERI1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,FEN1,HMGB1,HNMT,HNRNPC,HNRNPR,HPRT1,LSM3,LSM6,LSM7,METTL3,MLH1,MRTO4,NCBP1,NEIL2,NTHL1,NUDT5,PDE4A,PDE7A,PNPT1,POLR2D,PPP1R8,PSMD5,PSME3,RIDA,RNASEH1,SERBP1,SLIRP,SSB,SYNCRIP,TDG,TNFRSF1B,UPF2 |
| GO_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 56 | 17 | ANAPC1,ANAPC4,BUB1B,BUB3,CDC20,CENPE,CENPF,DLGAP5,FBXO5,GEN1,MAD2L1,NDC80,PLK1,TACC3,TRIP13,TTK,XRCC3 |
| GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 133 | 24 | BRCA1,CCNF,CCP110,CENPJ,CEP152,CEP192,CETN3,E2F4,GEN1,HAUS3,HAUS8,KIF11,MDM1,PCLAF,PLK1,POC1A,RANBP1,SASS6,SGO1,SPICE1,SSX2IP,STIL,XRCC2,XRCC3 |
| GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 339 | 37 | AURKAIP1,BLM,BRCA1,BRD7,BUB1B,BUB3,CARM1,CDC20,CENPF,DCLRE1B,DDIAS,DONSON,E2F4,E2F8,EME1,FBXO5,GEN1,GTSE1,KNTC1,MAD2L1,MRE11,NDC80,ORC1,PIDD1,PLK1,PNPT1,PRKDC,PSMD5,PSME3,PTTG1,SLFN11,TFDP1,TICRR,TRIP13,TTK,XRCC3,ZWILCH |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS | 0.0e+00 | 0.0e+00 | 1139 | 134 | 24 | BIRC5,CDC20,CENPE,CEP192,GPSM2,KIF11,KIF23,KIF2A,KIF4A,MAD2L1,MYBL2,MZT1,NDC80,PLK1,POC1A,SMC1A,SPC25,SPICE1,STIL,STMN1,TACC3,TTK,TUBG1,WRAP73 |
| GO_MEIOTIC_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 90 | 20 | BRIP1,BUB1B,CCNE1,CENPS,CENPX,EME1,FANCD2,MLH1,MLH3,MRE11,NDC1,PLK1,PTTG1,RAD51C,RMI1,SGO1,SGO2,SYCP1,TRIP13,TTK |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 0.0e+00 | 1139 | 944 | 64 | ACOX2,AKT1,ANLN,ARL5A,ATR,BARD1,BUB3,CARM1,CEP192,CHCHD4,CSE1L,DDX3X,ECT2,ESCO2,FAM83D,GTSE1,HASPIN,HEATR3,HSPD1,IMMP1L,IPO4,KIF20B,KNL1,KPNA3,MACROH2A1,MCM8,NDC80,NOL8,NUP107,NUP133,NUP155,NUP188,NUP35,NUP85,PARP1,PLK1,POLR1A,RABEP1,RPA1,RRS1,SAE1,SGTA,SIN3A,SIX1,SPAG5,SPCS1,SSB,STIL,TERF2,TERT,TFDP1,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,TRIM28,TTK,UBE2L3,WRAP53,XRCC5 |
| GO_REGULATION_OF_DNA_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1139 | 103 | 21 | ATAD5,BLM,FANCB,FIGN,FIGNL1,H1-3,IL7R,KLHL15,MLH1,MRE11,MSH6,PARP1,PARPBP,PAXIP1,POLQ,RTEL1,SMCHD1,TERF2,TIMELESS,USP51,WRAP53 |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 1139 | 1235 | 75 | AKT1,ATR,BLM,BRCA1,BRIP1,CCAR2,COPS9,CUL2,DDX3X,DNAJA3,DNMT3B,ECT2,EEF2K,EIF2B1,EIF2B3,FANCD2,FEN1,FIGNL1,FKBP4,H2AX,HDAC2,HMGN1,HNMT,HSPD1,LETM1,METAP1,METAP2,METTL3,MSH6,MYB,NDC1,NOC2L,NR4A2,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PARP1,PAXIP1,PBK,PCLAF,PER2,POLD1,POLE3,POLR2D,PPP1CC,PRKDC,PSIP1,PSMD5,PSME3,PSPH,PTGES3,RPA1,RPA3,SCARA3,SLC1A3,SMC1A,SPRTN,SUV39H1,SUV39H2,SYNGAP1,TERT,TGFB2,THBS1,TICRR,TIMELESS,TLR4,TMEM109,VHL,XRCC2,XRCC5 |
| GO_INTERSTRAND_CROSS_LINK_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 53 | 16 | ATR,CENPS,CENPX,DCLRE1B,EME1,EXO5,FANCA,FANCB,FANCC,FANCD2,FANCL,MCM8,MSH6,RPA1,RPA3,XRCC3 |
| GO_MEIOSIS_I_CELL_CYCLE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 118 | 22 | BRIP1,CCNE1,CENPS,CENPX,CKS2,EME1,FANCD2,FBXO5,MLH1,MLH3,MRE11,MSH5,MSH6,MYBL1,NDC1,PLK1,PTTG1,RAD51C,RAD54B,RMI1,SYCP1,TRIP13 |
| GO_SISTER_CHROMATID_COHESION | 0.0e+00 | 0.0e+00 | 1139 | 63 | 17 | BUB1B,CDC20,DDX12P,DSCC1,ESCO2,FEN1,HASPIN,KIF22,MACROH2A1,MCMBP,MRE11,PLK1,RAD51C,SGO1,SGO2,SMC1A,SMC5 |
| GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 0.0e+00 | 0.0e+00 | 1139 | 940 | 63 | AP2S1,APOBEC3B,C1QBP,CARM1,CENPF,CENPU,CPSF4,CRTC2,CUL2,DDX3X,EIF3B,EIF4E,EIF4G1,GTF2A2,GTF2F2,H2AX,HACD3,HSPD1,HTATSF1,IRF3,IVNS1ABP,KPNA3,LEF1,MAP3K7,MRE11,MSH6,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OAS3,POLA1,POLR2B,POLR2D,POLR2F,POLR2K,PPIH,PRKRA,PSIP1,PVR,RANBP1,RNGTT,RRP1B,SGTA,SIVA1,SKP2,SPCS1,SRCAP,SSB,SUV39H1,SYNCRIP,TAF11,TAF5,THOC3,TLR4,TOP1,TRIM28,TYMS,XRCC5 |
| GO_PROTEIN_CONTAINING_COMPLEX_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 326 | 35 | AURKAIP1,C12orf65,KIF18B,KIF24,KIF2A,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,PTCD3,SH3BP1,STMN1,SUPT16H |
| GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 636 | 50 | AFMID,AKT1,APEX1,APOBEC3B,DCPS,DCTPP1,DNA2,DND1,DUT,EIF4G1,ELAVL1,ENTPD2,ENTPD6,ERI1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,FEN1,HMGB1,HNMT,HNRNPC,HNRNPR,HPRT1,LSM3,LSM6,LSM7,METTL3,MLH1,MRTO4,NCBP1,NEIL2,NTHL1,NUDT5,PDE4A,PDE7A,PNPT1,POLR2D,PPP1R8,PSMD5,PSME3,RIDA,RNASEH1,SERBP1,SLIRP,SSB,SYNCRIP,TDG,TNFRSF1B,UPF2 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1139 | 1748 | 93 | ACOX2,AKT1,APEX1,ATAD5,BARD1,BIRC5,BRCA1,C1QBP,CACYBP,CCAR2,CIAPIN1,CTSC,CYCS,DCPS,DDIAS,DDX3X,DHODH,DLX1,DNAJA3,DNMT1,ECT2,EEF2K,EGR3,EIF4G1,ELL3,FFAR4,FIGNL1,FXN,GATA2,HDAC2,HMGB1,HSPD1,HSPE1,IER3IP1,IL20RA,IL7R,ING5,IVNS1ABP,KHDC1,KIF14,LEF1,MAD2L1,MAGEA3,MRE11,MYB,MYBBP1A,MYBL2,NCOA7,NME1,NOC2L,NR4A2,OPA1,PA2G4,PARP1,PHB,PIDD1,PLEKHG2,PLK1,PRDX3,PRELID1,PRKDC,PRKRA,PSME3,PTMA,PTPN2,RPS6KA1,RRP1B,RTKN2,SERBP1,SIN3A,SIX1,SKP2,SLC39A10,SLFN11,SOX7,ST18,STIL,STRADB,SYNGAP1,TERT,TFDP1,TGFB2,THBS1,TLR4,TMEM109,TNFRSF1B,TOMM22,TRAF7,UTP11,VHL,WNT10B,XRCC2,ZNF346 |
| GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS | 0.0e+00 | 0.0e+00 | 1139 | 148 | 24 | APEX1,CPSF3,CPSF4,CSTF2,CSTF3,DCPS,ELAC2,ERI1,EXO1,EXOSC2,EXOSC8,FEN1,ISG20L2,NCBP1,PNPT1,POLR3K,POP5,PPP1R8,RIDA,RNASEH1,RPP14,RRS1,TSEN54,UTP20 |
| GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 164 | 25 | AKT1,ANAPC4,APEX1,CCNE1,CDC45,CDC7,DBF4B,DDX3X,DLGAP5,EIF4E,EIF4G1,FBXO5,GEN1,KIF20B,LSM10,MACROH2A1,MAD2L1,NDC80,RAD51C,RANBP1,SIN3A,SMC5,TERT,WNT10B,XRCC3 |
| GO_DNA_PACKAGING | 0.0e+00 | 0.0e+00 | 1139 | 210 | 28 | ASF1B,CDAN1,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,H1-3,H2AX,H3C1,HELLS,HIRA,IPO4,KNL1,MACROH2A1,MCM2,NCAPD2,NCAPD3,NCAPG,NCAPG2,NOC2L,OIP5,POLE3,SMCHD1,SYCP1 |
| GO_MRNA_TRANSPORT | 0.0e+00 | 0.0e+00 | 1139 | 151 | 24 | AHCTF1,CETN3,CHTOP,CPSF3,CPSF4,DDX19A,EIF4E,IWS1,NCBP1,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,SRRM1,SRSF9,THOC3,UPF2,XPO7 |
| GO_ORGANELLE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 1139 | 622 | 49 | ASPM,CCP110,CDCA8,CENPE,CENPF,CENPJ,CEP152,CEP192,CEP41,CEP78,CLUH,CNIH3,CTSC,DLGAP5,FAM83D,FAM98A,GATA2,GPSM2,HAUS3,HAUS8,KIF14,KIF22,KIF23,KIF24,LTV1,MAD2L1,MLH1,NDC80,OPA1,PABPC1L,PLK1,PPP6R3,RAB8A,RASGRP1,RHOT2,RPGRIP1L,RRS1,SCFD2,SCLT1,SEC23IP,SHROOM2,SPAG5,SPICE1,STX2,TBCCD1,TMEM201,TUBA4A,TUBB4B,TUBG1 |
| GO_MRNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 0.0e+00 | 1139 | 111 | 21 | CHTOP,CPSF3,CPSF4,DDX19A,EIF4E,IWS1,NCBP1,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,NXF2B,POLR2D,SRRM1,SRSF9,THOC3,UPF2 |
| GO_NUCLEOTIDE_EXCISION_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 111 | 21 | AQR,BRIP1,FANCC,GTF2H3,HMGN1,LIG1,NEIL2,NTHL1,PARP1,POLD1,POLR2B,POLR2D,POLR2F,POLR2K,PRPF19,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3 |
| GO_TRANSCRIPTION_BY_RNA_POLYMERASE_I | 0.0e+00 | 0.0e+00 | 1139 | 66 | 17 | CD3EAP,DHX33,GTF2H3,HEATR1,IPPK,MACROH2A1,NCL,NOL11,POLR1A,POLR1B,POLR1C,POLR2F,POLR2K,TAF1B,TCOF1,TWISTNB,WDR75 |
| GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 394 | 38 | AKT1,AURKAIP1,BRCA1,BUB1B,BUB3,CCNF,CCP110,CDC20,CENPF,DNMT1,DNMT3B,FBXO5,FKBP4,FXN,GEN1,H1-3,HNRNPC,MACROH2A1,MAD2L1,MCM2,MDM1,MTF2,NDC80,NOC2L,OPA1,PARP1,PIF1,PLK1,PRELID1,PTTG1,RTEL1,SIN3A,STMN1,TERF2,TRIP13,TTK,XRCC3,XRCC5 |
| GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION | 0.0e+00 | 0.0e+00 | 1139 | 250 | 30 | CAND1,CD3EAP,ESR2,GTF2A2,GTF2F2,GTF2H3,GTF3C4,GTF3C5,HMGB1,MED20,MED4,NR4A2,PAXIP1,POLR1A,POLR1B,POLR1C,POLR2B,POLR2D,POLR2F,POLR2K,POLR3H,SUB1,TAF11,TAF1B,TAF5,TAF6L,TFAM,TRIM28,TWISTNB,WNT10B |
| GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 0.0e+00 | 1139 | 217 | 28 | ATAD5,ATR,AUNIP,BRCA1,CCAR2,DDIAS,ELL3,FANCB,FBXO5,FIGN,FIGNL1,H2AX,HMGB1,KLHL15,PARG,PARP1,PARPBP,PAXIP1,POLQ,PRKDC,RTEL1,SMCHD1,TERF2,TIMELESS,TRIM28,UBE2N,USP51,WRAP53 |
| GO_CHROMATIN_REMODELING | 0.0e+00 | 0.0e+00 | 1139 | 172 | 25 | CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHD7,HDAC2,HELLS,HNRNPC,INO80E,KNL1,MBD3,MYB,NUDT5,OIP5,PABPC1L,POLE3,PTMA,SMCHD1,SRCAP,SUV39H2,TAF6L,TOP1 |
| GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 484 | 42 | AKT1,C1QBP,CAPRIN2,CDK5RAP1,DDX3X,DHFR,DHX29,DNAJC24,EIF2B1,EIF3B,EIF4E,EIF4ENIF1,EIF4G1,EIF5B,ELAVL1,FASTKD2,FASTKD3,GEMIN5,GUF1,HNRNPR,KHDRBS1,METAP1,METTL3,MRPL13,MRPS27,NCBP1,NCL,PA2G4,PER2,POLR2D,PTCD3,RIDA,RPS6KA1,SELENOT,SYNCRIP,TCOF1,THBS1,TRMT10C,TSFM,TYMS,UQCC2,YTHDF1 |
| GO_REGULATION_OF_MRNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 325 | 34 | AKT1,APEX1,BARD1,C1QBP,CPSF4,DND1,EIF4G1,ELAVL1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,HNRNPC,HNRNPR,IWS1,KHDRBS1,LEO1,METTL3,NCBP1,NCL,PNPT1,PRPF19,PSMD5,PSME3,RIDA,SAFB,SAFB2,SERBP1,SF3B4,SFSWAP,SNRNP70,SRSF10,SRSF9,SYNCRIP |
| GO_DNA_INTEGRITY_CHECKPOINT | 0.0e+00 | 0.0e+00 | 1139 | 158 | 24 | ATR,BLM,BRCA1,BRIP1,CARM1,CCAR2,CDC45,CDC5L,DNA2,DONSON,E2F4,E2F8,EME1,GTSE1,H2AX,MRE11,ORC1,PIDD1,PLK1,PRKDC,PRPF19,TFDP1,TICRR,TIMELESS |
| GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 191 | 26 | ASF1B,CDAN1,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,H1-3,H2AX,H3C1,HELLS,HIRA,HIRIP3,IPO4,KNL1,MACROH2A1,MCM2,NOC2L,OIP5,POLE3,SMCHD1,SUPT16H,SUV39H2 |
| GO_RNA_MODIFICATION | 0.0e+00 | 0.0e+00 | 1139 | 161 | 24 | AARS2,ANKRD16,APOBEC3B,CDK5RAP1,CTU2,ELP6,FBL,FDXACB1,FTSJ3,GTPBP3,METTL2B,METTL3,MRM1,MRM2,NSUN2,OSGEP,PUS3,PUS7L,SSB,TGS1,TPRKB,TRMT10C,TRMT11,ZC3H13 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 1139 | 1781 | 92 | ADCY3,ADGRF1,AKT1,ARAP3,ARHGAP11A,ATP1B3,BMI1,CAPRIN2,CARM1,CDC20,CENPE,CHTOP,CHUK,CKS1B,CKS2,CRTC2,CYCS,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DEPDC1B,DHFR,DHX33,DNAJC24,DSCC1,ECT2,EIF4G1,ESR2,FXN,GTF2A2,GTF3C4,HACD3,HMGB1,HMGN1,HSPD1,HSPE1,IL1RAP,KHDC1,KIF14,MAP3K7,MRE11,MSH6,NCAPG2,NCBP1,NME1,NR4A2,PARP1,PGAM5,PIDD1,PKP4,PLK1,PPARGC1B,PRDX3,PRELID1,PRKAR2A,PRKRA,PSME3,PTGES3,RABEP1,RANBP1,RANBP3,RASGRP1,RFC2,RFC3,RFC4,RFC5,RTKN2,SAE1,SH3BP1,SLC39A10,SOX7,SSBP1,ST18,STMN1,STRADB,SYNGAP1,TERF2,TERT,TGFB2,THBS1,TLR4,TRAF7,TRIM28,UBE2L3,UBE2N,UBE2S,UHRF1,WNT10B,WRAP53,XRCC5 |
| GO_REGULATION_OF_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 122 | 21 | AUNIP,BRCA1,FANCB,FIGN,FIGNL1,H2AX,HMGB1,KLHL15,PARG,PARP1,PARPBP,POLQ,PRKDC,RTEL1,SMCHD1,TERF2,TIMELESS,TRIM28,UBE2N,USP51,WRAP53 |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 267 | 30 | BLM,BRCA1,BRD7,BUB1B,BUB3,CARM1,CDC20,CENPF,DONSON,E2F4,E2F8,FBXO5,GEN1,GTSE1,MACROH2A1,MAD2L1,MRE11,NDC80,ORC1,PIDD1,PLK1,PRKDC,PSMD5,PSME3,SLFN11,TFDP1,TICRR,TRIP13,TTK,XRCC3 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1301 | 74 | AFMID,AKT1,ANAPC1,ANAPC10,ANAPC4,AP2S1,APOBEC3B,ARMC8,BARD1,BUB1B,BUB3,CCAR2,CCNF,CDC20,CHAC2,CTRL,CTSC,CTSE,CUL2,DCTPP1,DDI2,DNAAF4,DUT,ENOSF1,ERLIN1,FAM83D,FBXL6,FBXO22,FBXO45,FBXO5,FOXRED2,GCSH,GGT2,GOT2,HNMT,HPRT1,HSPBP1,KIF14,KLHL15,MAD2L1,NEIL2,NEU3,NTHL1,PBK,PDE4A,PDE7A,PHB,PLK1,PPAT,PRPF19,PSMD5,PSME3,PTTG1,RIDA,RNF121,SGTA,SKP2,SNRNP70,SVIP,TBL1X,TDG,TNFRSF1B,UBE2G2,UBE2L3,UBE2S,UBE3C,UCHL5,UHRF1,UQCC2,USP10,USP18,USP37,USP51,WNT10B |
| GO_REGULATION_OF_GENE_SILENCING | 0.0e+00 | 0.0e+00 | 1139 | 154 | 23 | CDC45,DND1,DNMT1,EIF4G1,ELAVL1,H1-3,H3C1,HIRA,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLR2B,POLR2D,POLR2F,POLR2K,SIN3A,TERT,TRIM28 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 0.0e+00 | 0.0e+00 | 1139 | 1198 | 70 | AKT1,BRCA1,CAND1,CAPRIN2,CARM1,CDC5L,CHD7,CHUK,CRTC2,DDX3X,DLGAP5,DLX1,E2F4,E2F8,EGR3,ELL3,ERG,ERLIN1,GATA2,GTF2A2,GTF2F2,H2AZ1,HDAC2,HMGB1,HOXA2,IRF3,LEF1,LEO1,LRP5L,MIXL1,MTF2,MYB,MYBL1,MYBL2,NCL,NCOA7,NFATC3,NKRF,NR4A2,NUFIP1,ONECUT2,PAGR1,PARP1,PAXBP1,PAXIP1,PBX2,PFKM,PPARGC1B,PRDM15,PRKDC,RPS6KA1,RRP1B,SAFB,SIN3A,SIX1,ST18,SUB1,SUPT16H,TBL1X,TERT,TFDP1,TGFB2,TLR4,UHRF1,VEZF1,WDR5,WNT10B,YEATS4,ZBTB24,ZNF691 |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1935 | 96 | ACOX2,ADCY3,ADIPOR2,AKT1,APEX1,ATP1B3,ATR,BARD1,BLM,C7,CAND1,CCNE1,CHD7,CLNS1A,CMKLR1,COX11,CRTC2,DCLRE1B,DNA2,DNAJA3,E2F4,EIF4G1,EXO1,FABP5,FANCC,FEN1,FFAR4,FXN,GATA2,GLRX5,HACD3,HMGB1,HNRNPC,IL20RA,IL7R,LETM1,LPAR4,LRP5L,LYAR,MDM1,MRE11,NCAPG2,NME1,OPA1,PARP1,PER2,PFKM,PGAM5,PIF1,POLA1,POLA2,POLD1,POLE2,POLE3,PPARGC1B,PRDX3,PRIM1,PRKAR2A,PRKDC,PTGES3,PTPN2,RAD51C,RFC2,RFC3,RFC4,RFC5,RHOT2,RMI1,RPA1,RPA3,RTEL1,SELENOT,SFXN1,SIN3A,SLC39A10,SLC39A3,SMC5,SMC6,STMN1,TERF2,TERT,TLR4,TMX1,TMX2,TMX3,TWNK,UBAP2L,UBE2S,UNC80,VPS54,WDR36,WNT10B,WRAP53,XRCC3,XRCC5,ZNF236 |
| GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 0.0e+00 | 0.0e+00 | 1139 | 77 | 17 | CHUK,DDX3X,DHX33,HMGB1,HSPD1,IRF3,MRE11,POLR1C,POLR2F,POLR2K,POLR3B,POLR3G,POLR3H,POLR3K,PRKDC,TLR4,XRCC5 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 627 | 47 | ADCY3,AFMID,APOBEC3B,ATP5PF,CAD,DCTPP1,DHODH,DLAT,DTYMK,DUT,ENTPD2,ENTPD6,ERH,FLAD1,GART,GNPNAT1,HPRT1,IMPDH1,MTHFD2L,NDC1,NEIL2,NME1,NTHL1,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PAICS,PARG,PARP1,PDE4A,PDE7A,PFKM,PPAT,PRPS1,PRPS2,RRM2,SLC25A13,TDG,TK1,TYMS,UMPS |
| GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 57 | 15 | GCFC2,GEMIN2,GEMIN6,NCBP1,PRPF19,PRPF39,PSIP1,SFSWAP,SNRNP200,SNRPC,SNRPD1,SNRPG,SRSF10,SRSF9,TXNL4A |
| GO_SPLICEOSOMAL_SNRNP_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 39 | 13 | CLNS1A,GEMIN2,GEMIN4,GEMIN5,GEMIN6,PRPF19,SNRPC,SNRPD1,SNRPD3,SNRPF,SNRPG,SRSF10,TGS1 |
| GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 0.0e+00 | 0.0e+00 | 1139 | 130 | 21 | BEND3,BMI1,CDC45,DNMT1,DNMT3B,EED,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,MACROH2A1,MBD3,MTF2,POLE3,RRP8,SIN3A,SMCHD1,SUV39H1,TRIM28 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1005 | 62 | ACAD9,ACOX2,ADIPOR2,AKR1E2,AKT1,ALDH1B1,APEX1,CHCHD4,CIAPIN1,CISD1,COX11,CYB5RL,CYCS,DHFR,DHODH,DHRS7B,DLAT,DNAJC24,ECHDC1,FDXR,FOXRED2,FXN,GLRX5,GPD2,IDH3A,IMPDH1,JMJD7,KHK,L2HGDH,LBR,LDHB,LYRM7,MCAT,MMACHC,MTHFD2L,MYBBP1A,NDUFA12,NDUFAB1,NDUFAF5,OXNAD1,P3H3,PER2,PFKM,PNPT1,POLG2,PPP1CC,PRDX3,PRELID1,RPE,RRM2,RTN4IP1,SDHB,SDHD,SELENOT,SHPK,SLC25A13,SLC25A17,TDG,TMX1,TMX3,TYW1,VKORC1L1 |
| GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 192 | 25 | AKT1,ATAD5,ATR,BRCA1,DSCC1,FANCB,H2AX,HMGB1,MLH1,MRE11,PARP1,PAXIP1,PRKDC,PTGES3,RFC2,RFC3,RFC4,RFC5,RTEL1,SMCHD1,TIMELESS,TRIM28,UBE2N,WRAP53,XRCC5 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 0.0e+00 | 0.0e+00 | 1139 | 106 | 19 | AKT1,ANAPC4,APEX1,ATAD5,CCNE1,CDC45,CDC7,DBF4B,DDX3X,DLGAP5,EIF4G1,FAM83D,FBXO5,LSM10,PAGR1,RAD51C,SIN3A,TERT,WNT10B |
| GO_CHROMATIN_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 165 | 23 | ASF1B,CDAN1,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,CHAF1A,H1-3,H2AX,H3C1,HELLS,HIRA,IPO4,KNL1,MACROH2A1,MCM2,NOC2L,OIP5,POLE3,SMCHD1 |
| GO_PROTEOLYSIS | 0.0e+00 | 0.0e+00 | 1139 | 1779 | 89 | AKT1,ANAPC1,ANAPC10,ANAPC4,ARMC8,ATG4C,ATP23,AURKAIP1,BARD1,BIRC5,BRCA1,BUB1B,BUB3,CCAR2,CCNF,CCP110,CDC20,CTRL,CTSC,CTSE,CUL2,CYCS,DDI2,DDX3X,DNAAF4,EPOP,ERLIN1,FBXL6,FBXO22,FBXO45,FBXO5,FOXRED2,FXN,HDAC2,HMGB1,HSPBP1,HSPD1,HSPE1,IFT172,IMMP1L,INO80E,JMJD7,KHDC1,KIF14,KLHL15,LEF1,MAD2L1,MAGEA3,MAP3K7,METAP1,METAP2,OTUD6B,PARP1,PBK,PIDD1,PLK1,PRDX3,PRELID1,PRPF19,PSMD5,PSME3,PTTG1,RNF121,RPS6KA1,SENP3,SGTA,SKP2,SOX7,SPCS1,ST18,SVIP,TBL1X,THBS1,THOP1,TIMM17A,TNFRSF1B,UBE2G2,UBE2L3,UBE2N,UBE2S,UBE3C,UCHL5,UHRF1,USP10,USP18,USP37,USP51,VHL,WNT10B |
| GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY | 0.0e+00 | 0.0e+00 | 1139 | 42 | 13 | BLM,CENPS,CENPX,DNA2,DONSON,EME1,GEN1,MRE11,POLD1,RTEL1,SLFN11,TIMELESS,TONSL |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1724 | 87 | ADCY3,AKT1,AURKAIP1,BARD1,BMI1,BRCA1,BRD7,C1QBP,CAPRIN2,CDC20,CDCA2,CDK5RAP1,CENPE,CENPS,CENPX,CHTOP,CKS1B,CKS2,CTSC,CYCS,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DHX29,DHX33,DNMT1,DNMT3B,ECT2,EED,EIF4G1,ELAVL1,FASTKD2,FASTKD3,FBXO22,FFAR4,GUF1,HACD3,HDAC2,HMGB1,HSPBP1,HSPD1,HSPE1,KHDC1,KHDRBS1,KIF14,MAP3K7,METTL3,MRE11,MRPS27,MTF2,MYB,NCAPG2,PAXBP1,PAXIP1,PHB,PIDD1,PLK1,POLR2D,PRELID1,PRKAR2A,PSME3,RASGRP1,SGTA,SKP2,SLC39A10,SOX7,SPRTN,ST18,STRADB,SVIP,TGFB2,THBS1,TIMM17A,TLR4,TNFRSF1B,TRAF7,TRMT10C,TTK,UBE2L3,UBE2N,UBE2S,UHRF1,UQCC2,XRCC5,YTHDF1 |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 723 | 50 | ACOX2,ADIPOR2,ASNSD1,BRCA1,CAD,CRTC2,DCTPP1,DHFR,DHODH,DTYMK,DUT,ENOPH1,ENTPD2,ERLIN1,FABP5,FDXR,GART,GGT2,GOT2,GPD2,HACD3,HPRT1,IMPDH1,IPPK,LBR,MCAT,MMACHC,MTHFD2L,NDUFAB1,NEIL2,NME1,NTHL1,NUDT5,OSBPL3,PDE4A,PDE7A,PDSS1,PER2,PRPS1,PSPH,PTGES3,PTPN2,SDHAF3,SLC1A3,SLC25A13,SLC45A3,TDG,TK1,UMPS,WDR5 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 724 | 50 | AKT1,ANKRD13B,AURKAIP1,BRCA1,BUB1B,BUB3,CARM1,CCNF,CCP110,CDC20,CENPF,DDX3X,DNMT1,DNMT3B,EPHA3,FBXO5,FKBP4,FXN,GEN1,H1-3,HDAC2,HMGB1,HNRNPC,KIF14,MACROH2A1,MAD2L1,MCM2,MDM1,MTF2,NDC80,NOC2L,OPA1,PARP1,PIF1,PLK1,PRELID1,PTTG1,RTEL1,SEMA3G,SIN3A,STMN1,SVIP,SYNGAP1,TERF2,THBS1,TNFRSF1B,TRIP13,TTK,XRCC3,XRCC5 |
| GO_HISTONE_METHYLATION | 0.0e+00 | 0.0e+00 | 1139 | 138 | 21 | BEND3,BRCA1,CARM1,CHTOP,DNMT1,DNMT3B,EED,FBL,H1-3,IWS1,MACROH2A1,MTF2,MYB,PAGR1,PAXBP1,PAXIP1,RBBP5,SUV39H1,SUV39H2,WDR5,WDR82 |
| GO_NON_RECOMBINATIONAL_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 97 | 18 | ATP23,AUNIP,BARD1,BRCA1,DCLRE1B,H2AX,MLH1,MRE11,PAXIP1,POLA1,POLQ,PRKDC,PRPF19,SMCHD1,UBE2N,USP51,WRAP53,XRCC5 |
| GO_POSTREPLICATION_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 52 | 14 | BRCA1,PCLAF,POLD1,POLE2,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,SPRTN,UBE2N,UBE2NL,USP10 |
| GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 73 | 16 | AQR,GTF2H3,HMGN1,LIG1,POLD1,POLR2B,POLR2D,POLR2F,POLR2K,PRPF19,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3 |
| GO_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 44 | 13 | CAD,DHODH,DUT,GART,HPRT1,IMPDH1,PAICS,PPAT,PRPS1,PRPS2,TK1,TYMS,UMPS |
| GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | 0.0e+00 | 0.0e+00 | 1139 | 45 | 13 | BUB1B,BUB3,CDC20,CENPF,FBXO5,GEN1,MAD2L1,NDC80,PLK1,PTTG1,TRIP13,TTK,XRCC3 |
| GO_CILIUM_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 381 | 34 | ATG3,CCP110,CDKN3,CENPJ,CEP152,CEP192,CEP41,CEP78,CFAP20,CFAP46,CLUAP1,DNAAF4,DNAAF5,E2F4,HAUS3,HAUS8,HYLS1,IFT172,KIF24,ONECUT2,PLK1,POC1A,RAB8A,RPGRIP1L,SCLT1,SSX2IP,TCTEX1D2,TEKT4,TMEM237,TUBA4A,TUBB4B,TUBG1,WDR34,WRAP73 |
| GO_NEGATIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 37 | 12 | BUB1B,BUB3,CDC20,CENPF,FBXO5,GEN1,MAD2L1,NDC80,PLK1,TRIP13,TTK,XRCC3 |
| GO_MICROTUBULE_BASED_MOVEMENT | 0.0e+00 | 0.0e+00 | 1139 | 283 | 29 | CENPE,CFAP20,CFAP46,CLUAP1,DLGAP5,DNAAF4,DNAAF5,IFT172,KIF11,KIF14,KIF15,KIF18B,KIF20A,KIF20B,KIF22,KIF23,KIF24,KIF2A,KIF4A,KLC2,OPA1,RASGRP1,RHOT2,SSX2IP,TCTEX1D2,TEKT4,TERF2,TMEM201,WDR34 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1117 | 64 | ADCY3,AKT1,APOBEC3B,ATP5PF,B3GALNT1,B3GALNT2,C1GALT1,CAD,DCTPP1,DHODH,DLAT,DTYMK,DUT,ENGASE,ERH,FAM20B,FKTN,FUT1,FUT10,GALNT14,GART,GK5,GNPNAT1,GPD2,HPRT1,HS3ST2,HS3ST3A1,IMPDH1,KHK,NDC1,NEIL2,NEU3,NME1,NTHL1,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PAICS,PARG,PARP1,PDE4A,PDE7A,PFKM,POGLUT2,PPAT,PRPS1,PRPS2,RPE,RRM2,RXYLT1,SHPK,SLC25A13,TDG,TK1,TYMS,UBE2G2,UMPS,XYLB |
| GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1139 | 68 | 15 | DHX30,EBNA1BP2,FASTKD2,FTSJ3,HEATR3,LAS1L,MDN1,MRPL11,MRTO4,NOC2L,NOP16,RRS1,URB1,WDR12,WDR74 |
| GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 478 | 38 | AKT1,ANAPC1,ANAPC10,ANAPC4,ARMC8,BUB1B,BUB3,CCAR2,CCNF,CDC20,CUL2,DDI2,DNAAF4,ERLIN1,FBXL6,FBXO22,FBXO45,FBXO5,FOXRED2,HSPBP1,KIF14,KLHL15,MAD2L1,PBK,PLK1,PRPF19,PSMD5,PSME3,PTTG1,RNF121,SGTA,SKP2,SVIP,TBL1X,UBE2G2,UBE2S,UCHL5,WNT10B |
| GO_MODIFICATION_DEPENDENT_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 642 | 45 | AKT1,ANAPC1,ANAPC10,ANAPC4,ARMC8,BUB1B,BUB3,CCAR2,CCNF,CDC20,CUL2,ERLIN1,EXOSC2,EXOSC8,FBXL6,FBXO22,FBXO45,FBXO5,FOXRED2,HSPBP1,KIF14,KLHL15,MAD2L1,PBK,PLK1,PNPT1,PSMD5,PSME3,PTTG1,RNF121,SGTA,SKP2,SVIP,TBL1X,UBE2G2,UBE2L3,UBE2S,UBE3C,UCHL5,UHRF1,USP10,USP18,USP37,USP51,WNT10B |
| GO_DNA_STRAND_ELONGATION | 0.0e+00 | 0.0e+00 | 1139 | 24 | 10 | DCLRE1B,DNA2,GINS1,GINS3,LIG1,MRE11,POLA1,RFC3,RFC4,TERT |
| GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME | 0.0e+00 | 0.0e+00 | 1139 | 83 | 16 | ATR,BUB3,CARM1,ESCO2,HASPIN,KNL1,MACROH2A1,MCM8,NDC80,PLK1,RPA1,TERF2,TERT,TTK,WRAP53,XRCC5 |
| GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION | 0.0e+00 | 0.0e+00 | 1139 | 60 | 14 | AURKAIP1,BUB1B,BUB3,CDC20,CENPF,FBXO5,GEN1,MAD2L1,NDC80,PLK1,PTTG1,TRIP13,TTK,XRCC3 |
| GO_GENE_SILENCING | 0.0e+00 | 0.0e+00 | 1139 | 530 | 40 | BEND3,BMI1,CDC45,CLP1,DND1,DNMT1,EED,EIF4G1,ELAVL1,ERI1,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,MBD3,METTL3,NCBP1,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLE3,POLR2B,POLR2D,POLR2F,POLR2K,PRKRA,RRP8,SIN3A,SMCHD1,SRCAP,SUV39H1,TERT,TRIM28 |
| GO_CHROMATIN_ORGANIZATION_INVOLVED_IN_REGULATION_OF_TRANSCRIPTION | 0.0e+00 | 0.0e+00 | 1139 | 124 | 19 | BEND3,BMI1,CDC45,DNMT1,EED,H1-3,H3C1,HDAC2,HELLS,HIRA,HMGB1,MBD3,PABPC1L,POLE3,RRP8,SIN3A,SMCHD1,SUV39H1,TRIM28 |
| GO_RESPONSE_TO_RADIATION | 0.0e+00 | 0.0e+00 | 1139 | 441 | 36 | AKT1,ATR,BLM,BRCA1,CCAR2,COPS9,DNMT3B,ECT2,FANCD2,FEN1,FIGNL1,H2AX,HMGN1,METAP1,METAP2,METTL3,MSH6,NOC2L,PARP1,PAXIP1,PBK,PCLAF,PER2,POLD1,POLE3,PPP1CC,PRKDC,SCARA3,SLC1A3,SMC1A,SPRTN,SYNGAP1,TICRR,TMEM109,XRCC2,XRCC5 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 0.0e+00 | 1139 | 532 | 40 | AKT1,ALDH1B1,ATP5PF,CIAPIN1,CISD1,COX11,CYCS,DLAT,FDXR,FXN,GLRX5,GPD2,IDH3A,KHK,LYRM7,MYBBP1A,NDC1,NDUFA12,NDUFAB1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PER2,PFKM,PNPT1,POLG2,PPP1CC,PRELID1,RPE,SDHB,SDHD,SHPK,SLC25A13,TEFM,UQCC2,XYLB |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 0.0e+00 | 1139 | 603 | 43 | AKT1,ATAD5,BRCA1,CCAR2,CTSC,CUL2,DDIAS,DDX3X,ELL3,FIGNL1,FXN,GGCT,IL20RA,ING5,IVNS1ABP,MAGEA3,MLH1,MSH6,MYBBP1A,NOC2L,NR4A2,OPA1,PARP1,PIDD1,PRELID1,PRKDC,PRKRA,PSME3,PTPN2,RHOT2,RRP8,RTKN2,SIVA1,ST18,STRADB,TERT,TFDP1,TGFB2,THBS1,TLR4,TMEM109,TNFRSF1B,TRAF7 |
| GO_SNRNA_TRANSCRIPTION | 0.0e+00 | 0.0e+00 | 1139 | 72 | 15 | ELL3,GTF2A2,GTF2F2,ICE1,INTS2,INTS8,INTS9,NCBP1,POLR2B,POLR2D,POLR2F,POLR2K,SNAPC4,TAF11,TAF5 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 1139 | 1429 | 74 | ADCY3,AKT1,ARAP3,ARHGAP11A,ATP1B3,BMI1,CDC20,CENPE,CHTOP,CKS1B,CKS2,CYCS,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DEPDC1B,DHFR,DNAJC24,DSCC1,ECT2,FXN,GTF3C4,HACD3,HMGB1,HMGN1,HSPD1,HSPE1,KHDC1,KIF14,MAP3K7,MRE11,MSH6,NCAPG2,NR4A2,PGAM5,PIDD1,PKP4,PLK1,PPARGC1B,PRELID1,PRKAR2A,PRKRA,PSME3,PTGES3,RABEP1,RANBP1,RANBP3,RASGRP1,RFC2,RFC3,RFC4,RFC5,SAE1,SH3BP1,SLC39A10,SOX7,SSBP1,ST18,STRADB,SYNGAP1,TERF2,TERT,TGFB2,THBS1,TLR4,TRAF7,UBE2L3,UBE2N,UBE2S,UHRF1,WRAP53,XRCC5 |
| GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 51 | 13 | PCLAF,POLA1,POLD1,POLE2,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,SPRTN,SYCP1,USP10 |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1016 | 59 | ADCY3,ADIPOR2,AKT1,ASF1B,ASPM,BRIP1,C1QBP,CAD,DDX3X,DHODH,DND1,ELL3,FANCA,FANCC,FANCD2,FANCL,FBXO5,FIGNL1,FKBP4,FUT10,GGT2,GMCL1,GOT2,H2AX,HDAC2,KHDRBS1,KNL1,MCM8,METTL3,MLH1,MLH3,MYBL1,MYCBP,NDC1,NSUN2,PABPC1L,PAFAH1B2,PAFAH1B3,PLK1,POC1A,POLR1B,PPAT,PRDX3,PTTG1,RAD51C,RPL39L,SEPTIN12,SLIRP,SPIN4,STX2,SYCP1,TEKT4,TRIM28,TRIP13,TSGA10,TTK,TUBGCP3,UBAP2L,UMPS |
| GO_RNA_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 404 | 34 | AKT1,APEX1,DCPS,DNA2,DND1,EIF4G1,ELAVL1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,FEN1,HNRNPC,HNRNPR,LSM3,LSM6,LSM7,METTL3,MLH1,MRTO4,NCBP1,PNPT1,POLR2D,PPP1R8,PSMD5,PSME3,RIDA,RNASEH1,SERBP1,SLIRP,SSB,SYNCRIP,TNFRSF1B,UPF2 |
| GO_IMMUNE_SYSTEM_DEVELOPMENT | 0.0e+00 | 0.0e+00 | 1139 | 990 | 58 | ANLN,ATAD5,BMI1,CHD7,CIAPIN1,DHRS7B,DNAJA3,EGR3,ESCO2,EXO1,FANCA,FANCD2,FARP2,FUT10,GATA2,GLRX5,H3C1,HMGB1,HSPD1,IL12RB1,IL7R,LBR,LEF1,LEO1,LRP5L,LYAR,METTL3,MIXL1,MLH1,MSH6,MYB,NCAPG2,NME1,PARP1,PAXIP1,POLQ,PPARGC1B,PRDX3,PRELID1,PRKDC,PSMD5,PSME3,PTPN2,RASGRP1,RBBP5,RHOH,RRS1,RTKN2,SFXN1,SIN3A,SIX1,TGFB2,THBS1,TLR4,WDR5,WNT10B,XRCC5,ZBTB24 |
| GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 177 | 22 | ANAPC4,ATR,BRCA1,BRD7,CHTOP,DLGAP5,DNMT1,DNMT3B,EED,FEN1,MACROH2A1,MRE11,MTF2,MYB,PAXBP1,PAXIP1,RTEL1,SIN3A,SMC5,TRIM28,UBE2N,XRCC5 |
| GO_BASE_EXCISION_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 43 | 12 | APEX1,APEX2,DNA2,FEN1,LIG1,NEIL2,NTHL1,POLD1,POLQ,RPA1,RPA3,TDG |
| GO_HOMOLOGOUS_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1139 | 53 | 13 | BRIP1,CENPS,CENPX,EME1,MLH1,MLH3,MRE11,MSH5,RAD51C,RAD54B,RMI1,SYCP1,TRIP13 |
| GO_PEPTIDYL_LYSINE_METHYLATION | 0.0e+00 | 0.0e+00 | 1139 | 130 | 19 | BEND3,BRCA1,DNMT1,DNMT3B,EED,EEF1AKMT1,EEF2KMT,H1-3,IWS1,MACROH2A1,MTF2,MYB,PAGR1,PAXIP1,RBBP5,SUV39H1,SUV39H2,WDR5,WDR82 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 620 | 43 | AKT1,ALDH1B1,AMY2A,B3GALNT1,COX11,CRTC2,DLAT,ENOSF1,FABP5,FUT1,FUT10,GK5,GLB1L2,GOT2,GPD2,IDH3A,IPPK,KHK,LDHB,MLEC,NDC1,NEU3,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PARG,PER2,PFKM,PGM5,PPP1CC,PTPN2,RPE,SDHAF3,SHPK,SLC25A13,SLC45A3,WDR5,XYLB |
| GO_IMPORT_INTO_NUCLEUS | 0.0e+00 | 0.0e+00 | 1139 | 164 | 21 | AKT1,CSE1L,ECT2,GEMIN2,GEMIN4,GEMIN5,GEMIN6,HEATR3,IPO4,KPNA3,NUP107,NUP133,NUP155,NUP188,NUP35,NUP85,SNRPD1,SNRPD3,SNRPF,SNRPG,TRIM28 |
| GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION | 0.0e+00 | 0.0e+00 | 1139 | 35 | 11 | CLP1,CPSF3,CPSF4,CSTF2,CSTF3,LSM10,NCBP1,SNRPD3,SNRPF,SNRPG,TTF2 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1880 | 88 | ADCY3,AKT1,BLM,BMI1,BRCA1,BRD7,CAPRIN2,CCAR2,CCNE1,CCNF,CDC20,CDCA2,CDK5RAP1,CDKN3,CENPE,CENPS,CENPX,CHTOP,CKS1B,CKS2,COPS9,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DHX33,DNMT1,DNMT3B,ECT2,EED,EEF2K,EIF4G1,FAM83D,FBXO5,FEM1A,FFAR4,FKTN,GATA2,HACD3,HDAC2,HMGB1,HPF1,HSPBP1,IVNS1ABP,IWS1,KIF14,MACROH2A1,MAD2L1,MAP3K7,MRE11,MTF2,MYB,NCAPG2,NCOA7,NOC2L,PAXBP1,PAXIP1,PBK,PER2,PHB,PKMYT1,PLK1,PPP1R8,PPP2R3B,PPP6R3,PRDM15,PRKAR2A,PRKDC,PRMT3,PTPN2,RASGRP1,SIN3A,SKP2,SLC39A10,SPRTN,STRADB,SVIP,SYNGAP1,TGFB2,THBS1,TLR4,TRAF7,TTK,UBE2L3,UBE2N,UBE2S,XRCC5 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 104 | 17 | CAD,DCTPP1,DHODH,DTYMK,DUT,ENTPD2,HPRT1,IMPDH1,NEIL2,NME1,NTHL1,NUDT5,PDE4A,PDE7A,TDG,TK1,UMPS |
| GO_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 66 | 14 | BRIP1,BUB1B,CCNE1,FANCD2,MLH1,MLH3,MRE11,NCAPD2,NCAPD3,NDC1,RAD51C,SGO2,SYCP1,TRIP13 |
| GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION | 0.0e+00 | 0.0e+00 | 1139 | 55 | 13 | ASF1B,CENPH,CENPI,CENPL,CENPS,CENPU,CENPX,HIRA,IPO4,KNL1,OIP5,POLE3,SUPT16H |
| GO_TRANSCRIPTION_BY_RNA_POLYMERASE_III | 0.0e+00 | 0.0e+00 | 1139 | 55 | 13 | BRCA1,GTF3C4,GTF3C5,ICE1,IVNS1ABP,POLR1C,POLR2F,POLR2K,POLR3B,POLR3G,POLR3H,POLR3K,SNAPC4 |
| GO_RESPONSE_TO_HEAT | 0.0e+00 | 0.0e+00 | 1139 | 183 | 22 | AKT1,ATR,CCAR2,DNAJA3,EIF2B1,EIF2B3,FKBP4,HDAC2,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLR2D,PSIP1,PTGES3,RPA1,RPA3,THBS1 |
| GO_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 938 | 55 | AKT1,ANAPC1,ANAPC10,ANAPC4,AP2S1,ARMC8,BARD1,BUB1B,BUB3,CCAR2,CCNF,CDC20,CTRL,CTSC,CTSE,CUL2,DDI2,DNAAF4,ERLIN1,FAM83D,FBXL6,FBXO22,FBXO45,FBXO5,FOXRED2,HSPBP1,KIF14,KLHL15,MAD2L1,PBK,PHB,PLK1,PRPF19,PSMD5,PSME3,PTTG1,RNF121,SGTA,SKP2,SNRNP70,SVIP,TBL1X,TNFRSF1B,UBE2G2,UBE2L3,UBE2S,UBE3C,UCHL5,UHRF1,UQCC2,USP10,USP18,USP37,USP51,WNT10B |
| GO_PROTEIN_ACETYLATION | 0.0e+00 | 0.0e+00 | 1139 | 202 | 23 | BEND3,BRCA1,BRD7,CRTC2,DSCC1,ESCO2,GATA2,GTF3C4,HDAC2,ING5,IWS1,LEF1,MAP3K7,MBD3,NOC2L,PAXIP1,POLE3,SIN3A,SRCAP,TAF5,TAF6L,WDR5,YEATS4 |
| GO_CENTROMERE_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 56 | 13 | CENPE,CENPF,CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,HELLS,KNL1,OIP5,POLE3 |
| GO_PEPTIDYL_LYSINE_ACETYLATION | 0.0e+00 | 0.0e+00 | 1139 | 168 | 21 | BEND3,BRCA1,BRD7,CRTC2,GATA2,GTF3C4,HDAC2,ING5,IWS1,LEF1,MAP3K7,MBD3,NOC2L,PAXIP1,POLE3,SIN3A,SRCAP,TAF5,TAF6L,WDR5,YEATS4 |
| GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1139 | 46 | 12 | FANCB,FIGN,FIGNL1,KLHL15,PARP1,PARPBP,POLQ,RTEL1,SMCHD1,TIMELESS,USP51,WRAP53 |
| GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS | 0.0e+00 | 0.0e+00 | 1139 | 68 | 14 | BMS1,DHX37,HEATR1,LSM6,LTV1,MRPS7,NOL10,NOL11,NOM1,PWP2,RRS1,TBL3,UTP20,UTP3 |
| GO_MITOTIC_SPINDLE_ASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 57 | 13 | BIRC5,CDC20,CEP192,KIF11,KIF23,KIF2A,KIF4A,MYBL2,MZT1,PLK1,SMC1A,SPICE1,WRAP73 |
| GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 1139 | 29 | 10 | CCNE1,CDC45,DHFR,E2F4,FBXO5,ORC1,POLA1,RRM2,TFDP1,TYMS |
| GO_CELLULAR_COMPONENT_DISASSEMBLY | 0.0e+00 | 0.0e+00 | 1139 | 547 | 39 | ATG3,AURKAIP1,C12orf65,HMGB1,KIF18B,KIF24,KIF2A,MRPL11,MRPL12,MRPL13,MRPL16,MRPL18,MRPL21,MRPL28,MRPL3,MRPL30,MRPL35,MRPL38,MRPL39,MRPL4,MRPL42,MRPL43,MRPL46,MRPS10,MRPS12,MRPS17,MRPS22,MRPS25,MRPS26,MRPS27,MRPS31,MRPS7,MRPS9,PLK1,PTCD3,SH3BP1,STMN1,SUPT16H,VRK1 |
| GO_MISMATCH_REPAIR | 0.0e+00 | 0.0e+00 | 1139 | 38 | 11 | EXO1,HMGB1,LIG1,MLH1,MLH3,MSH5,MSH6,POLD1,RPA1,RPA3,TDG |
| GO_MITOTIC_RECOMBINATION | 0.0e+00 | 0.0e+00 | 1139 | 22 | 9 | GEN1,MLH1,MRE11,RAD51C,RAD54B,SMC5,SMC6,TERF2,XRCC3 |
| GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 72 | 14 | CAD,DHODH,DTYMK,DUT,GART,HPRT1,IMPDH1,PAICS,PPAT,PRPS1,PRPS2,TK1,TYMS,UMPS |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 782 | 48 | AKT1,ANAPC1,ANAPC10,ANAPC4,AP2S1,ARMC8,BUB1B,BUB3,CCAR2,CCNF,CDC20,CTSC,CUL2,DDI2,DNAAF4,ERLIN1,FBXL6,FBXO22,FBXO45,FBXO5,FOXRED2,HSPBP1,KIF14,KLHL15,MAD2L1,PBK,PLK1,PRPF19,PSMD5,PSME3,PTTG1,RNF121,SGTA,SKP2,SVIP,TBL1X,UBE2G2,UBE2L3,UBE2S,UBE3C,UCHL5,UHRF1,UQCC2,USP10,USP18,USP37,USP51,WNT10B |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 1139 | 1164 | 62 | AARS2,ACAD9,ACOX2,ADIPOR2,AFMID,AKT1,ASNSD1,BRCA1,CAD,DARS2,DHFR,DLAT,ECHDC1,ENOPH1,ENOSF1,ERLIN1,FABP5,GART,GCSH,GGT2,GOT2,HACD3,HNMT,IDH3A,L2HGDH,LARS2,LDHB,MARS2,MCAT,MTHFD2L,NARS2,NDC1,NDUFAB1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OSBPL3,PER2,PFKM,PPAT,PRPS1,PSMD5,PSME3,PSPH,PTGES3,RARS1,RIDA,SARS2,SDHAF3,SDHB,SLC16A9,SLC19A1,SLC1A3,SLC25A17,SLC45A3,SLC5A6,TYMS,XYLB |
| GO_TYPE_I_INTERFERON_PRODUCTION | 0.0e+00 | 0.0e+00 | 1139 | 129 | 18 | CHUK,DDX3X,DHX33,HMGB1,HSPD1,IRF3,MRE11,POLR1C,POLR2F,POLR2K,POLR3B,POLR3G,POLR3H,POLR3K,PRKDC,RNF26,TLR4,XRCC5 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 1139 | 1881 | 86 | AJAP1,AKT1,ASPM,C1QBP,CAPRIN2,CARM1,CDC20,CDK5RAP1,CHD7,CMKLR1,DDX56,DLL3,DLX1,DNMT1,DNMT3B,ECT2,EEF2K,EGR3,EIF4E,EIF4ENIF1,EIF4G1,ELL3,EPHA3,FANCA,FANCD2,FBXO22,FBXO5,FKBP4,GATA2,GPR173,H3C1,HDAC2,HMGB1,HOXA2,IL12RB1,IL7R,KIF14,KIF20B,LEF1,LEO1,MACROH2A1,METTL3,MIXL1,MYB,NCAPG2,NFATC3,NME1,OPA1,PA2G4,PARP1,PER2,PLXNA1,PPARGC1B,PPP1CC,PRELID1,PRPF19,PSMD5,PSME3,PTPN2,RASGRP1,RBBP5,RBPMS2,RHOH,RPS6KA1,RTN4IP1,SEMA3G,SIN3A,SIX1,SLC45A3,SYNGAP1,TERT,TGFB2,THBS1,TLR4,TNFRSF1B,TNFRSF21,UQCC2,VEZF1,VHL,WDR36,WDR5,WNT10B,XRCC2,XRCC5,YTHDF1,ZNF488 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 1139 | 1030 | 57 | AKT1,ATAD5,BARD1,BIRC5,BRCA1,CACYBP,CCAR2,CIAPIN1,DCPS,DDIAS,DDX3X,DLX1,DNAJA3,DNMT1,EEF2K,EGR3,EIF4G1,ELL3,FFAR4,FIGNL1,FXN,GATA2,HDAC2,HSPD1,IL7R,IVNS1ABP,KIF14,LEF1,MAD2L1,MAGEA3,MRE11,NCOA7,NOC2L,NR4A2,OPA1,PA2G4,PIDD1,PLK1,PRDX3,PRELID1,PRKDC,PSME3,PTMA,RPS6KA1,RTKN2,SIN3A,SIX1,SLC39A10,STIL,STRADB,SYNGAP1,TERT,THBS1,TMEM109,TNFRSF1B,VHL,XRCC2 |
| GO_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING | 0.0e+00 | 0.0e+00 | 1139 | 116 | 17 | DND1,EIF4G1,ELAVL1,H3C1,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLR2B,POLR2D,POLR2F,POLR2K,TERT |
| GO_TRANSLESION_SYNTHESIS | 0.0e+00 | 0.0e+00 | 1139 | 41 | 11 | PCLAF,POLD1,POLE2,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,SPRTN,USP10 |
| GO_NUCLEOSOME_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1139 | 184 | 21 | ASF1B,CENPH,CENPI,CENPL,CENPS,CENPU,CENPX,CHAF1A,H1-3,H2AX,H3C1,HIRA,IPO4,KNL1,MACROH2A1,MCM2,OIP5,POLE3,PTMA,SRCAP,SUPT16H |
| GO_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 1139 | 33 | 10 | CAD,DHODH,GART,HPRT1,IMPDH1,PAICS,PPAT,PRPS1,PRPS2,UMPS |
| GO_RRNA_TRANSCRIPTION | 0.0e+00 | 1.0e-07 | 1139 | 33 | 10 | CD3EAP,GTF3C4,GTF3C5,IPPK,MACROH2A1,NCL,NOL11,POLR1B,TAF1B,TCOF1 |
| GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR | 0.0e+00 | 1.0e-07 | 1139 | 78 | 14 | AUNIP,FANCB,FIGN,FIGNL1,KLHL15,PARP1,PARPBP,POLQ,PRKDC,RTEL1,SMCHD1,TIMELESS,USP51,WRAP53 |
| GO_MRNA_CIS_SPLICING_VIA_SPLICEOSOME | 0.0e+00 | 1.0e-07 | 1139 | 34 | 10 | DCPS,NCBP1,PRPF39,PRPF40A,PSIP1,SFSWAP,SNRNP200,SNRPC,SRSF10,SRSF9 |
| GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT | 0.0e+00 | 1.0e-07 | 1139 | 79 | 14 | ATR,CCAR2,FKBP4,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PTGES3,RPA1,RPA3 |
| GO_PROTEIN_ACYLATION | 0.0e+00 | 1.0e-07 | 1139 | 246 | 24 | BEND3,BRCA1,BRD7,CRTC2,DSCC1,ESCO2,GATA2,GTF3C4,HDAC2,ING5,IWS1,LEF1,MAP3K7,MBD3,NOC2L,PAXIP1,POLE3,SIN3A,SRCAP,TAF5,TAF6L,WDR5,YEATS4,ZDHHC6 |
| GO_REGULATION_OF_CHROMATIN_ORGANIZATION | 0.0e+00 | 1.0e-07 | 1139 | 190 | 21 | BRCA1,BRD7,CDC45,CHTOP,DNMT1,DNMT3B,EED,GATA2,H1-3,HIRA,IWS1,MACROH2A1,MKI67,MTF2,MYB,NOC2L,PAXBP1,PAXIP1,SIN3A,TRIM28,UBE2N |
| GO_CENTROSOME_DUPLICATION | 0.0e+00 | 1.0e-07 | 1139 | 67 | 13 | BRCA1,CCNF,CCP110,CENPJ,CEP152,CEP192,GEN1,MDM1,POC1A,SASS6,SPICE1,STIL,XRCC3 |
| GO_MATURATION_OF_5_8S_RRNA | 0.0e+00 | 1.0e-07 | 1139 | 26 | 9 | ERI1,EXOSC2,EXOSC8,FTSJ3,LAS1L,RRS1,URB1,UTP20,WDR12 |
| GO_HISTONE_H3_K4_METHYLATION | 0.0e+00 | 1.0e-07 | 1139 | 56 | 12 | BEND3,BRCA1,DNMT1,DNMT3B,H1-3,MACROH2A1,MYB,PAGR1,PAXIP1,RBBP5,WDR5,WDR82 |
| GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION | 0.0e+00 | 1.0e-07 | 1139 | 45 | 11 | BLM,FANCB,H1-3,KLHL15,MLH1,MSH6,PARPBP,POLQ,RTEL1,SMCHD1,TERF2 |
| GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 1139 | 125 | 17 | AUNIP,BLM,FANCB,H1-3,HNRNPC,KLHL15,MLH1,MSH6,PARP1,PARPBP,PIF1,POLQ,RTEL1,SMCHD1,TERF2,TRIM28,XRCC5 |
| GO_CILIARY_BASAL_BODY_PLASMA_MEMBRANE_DOCKING | 0.0e+00 | 1.0e-07 | 1139 | 95 | 15 | CCP110,CENPJ,CEP152,CEP192,CEP41,CEP78,HAUS3,HAUS8,KIF24,PLK1,RPGRIP1L,SCLT1,TUBA4A,TUBB4B,TUBG1 |
| GO_NUCLEOBASE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 1139 | 19 | 8 | CAD,DHODH,GART,HPRT1,PAICS,PPAT,PRPS1,UMPS |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 1.0e-07 | 1139 | 232 | 23 | AKT1,BMI1,BRCA1,CDC20,CENPS,CENPX,COPS9,DCUN1D4,DCUN1D5,FBXO5,FEM1A,HSPBP1,IVNS1ABP,MAD2L1,PAXIP1,PER2,PLK1,PRMT3,SKP2,SPRTN,UBE2L3,UBE2N,UBE2S |
| GO_CELL_PROJECTION_ASSEMBLY | 0.0e+00 | 1.0e-07 | 1139 | 567 | 38 | ANLN,ATG3,CCP110,CDKN3,CENPJ,CEP152,CEP192,CEP41,CEP78,CFAP20,CFAP46,CLUAP1,DNAAF4,DNAAF5,E2F4,FAM98A,HAUS3,HAUS8,HYLS1,IFT172,KIF24,NUP85,ONECUT2,PLK1,POC1A,RAB8A,RPGRIP1L,SCLT1,SSX2IP,TCTEX1D2,TEKT4,TMEM237,TSGA10,TUBA4A,TUBB4B,TUBG1,WDR34,WRAP73 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 2.0e-07 | 1139 | 995 | 54 | AKT1,ASPM,ATP5PF,CCDC85C,CDK5RAP1,CENPF,CHD7,CLP1,DHX30,DLX1,DMBX1,EED,EIF2B1,EIF2B3,FANCC,FANCD2,FBXO45,FUT10,GART,GATA2,GNB4,H2AX,HDAC2,HNMT,HOXA2,HPRT1,IFT172,KIF14,KLHL17,LEF1,MBD3,METTL3,NME1,NPTX1,NR4A2,PAFAH1B2,PAFAH1B3,PRKDC,PRPF19,RIDA,RPGRIP1L,SHROOM2,SIN3A,SIX1,SLC45A3,STIL,STMN1,TACC3,TLR4,TNFRSF1B,TNFRSF21,UTP3,XRCC5,ZNF488 |
| GO_MRNA_3_END_PROCESSING | 0.0e+00 | 2.0e-07 | 1139 | 98 | 15 | BARD1,CHTOP,CLP1,CPSF3,CPSF4,CSTF2,CSTF3,LEO1,NCBP1,PABPC1L,PNPT1,POLR2D,SRRM1,SRSF9,THOC3 |
| GO_MATURATION_OF_SSU_RRNA | 0.0e+00 | 2.0e-07 | 1139 | 47 | 11 | BMS1,DHX37,HEATR1,LSM6,NOL10,NOL11,PWP2,RRS1,TBL3,UTP20,UTP3 |
| GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 2.0e-07 | 1139 | 99 | 15 | APOBEC3B,CAD,DCTPP1,DHODH,DTYMK,DUT,ERH,NEIL2,NME1,NTHL1,PRPS1,TDG,TK1,TYMS,UMPS |
| GO_CHROMATIN_REMODELING_AT_CENTROMERE | 0.0e+00 | 2.0e-07 | 1139 | 48 | 11 | CENPH,CENPI,CENPL,CENPS,CENPU,CENPV,CENPX,HELLS,KNL1,OIP5,POLE3 |
| GO_NCRNA_3_END_PROCESSING | 0.0e+00 | 2.0e-07 | 1139 | 48 | 11 | ELAC2,ERI1,EXOSC2,EXOSC8,FBL,INTS2,INTS8,POLR3K,PTCD1,SSB,TRMT10C |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 0.0e+00 | 2.0e-07 | 1139 | 976 | 53 | ADCY3,AKT1,BLM,BMI1,CCNE1,CCNF,CDC20,CDK5RAP1,CDKN3,CENPE,CKS1B,CKS2,COX11,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DSCC1,ECT2,FBXO5,FEM1A,HACD3,HMGN1,KIF14,MACROH2A1,MAD2L1,MAP3K7,MRE11,NCAPG2,PIF1,PKMYT1,PLK1,PRDX3,PRKAR2A,PTGES3,PTPN2,RASGRP1,RFC2,RFC3,RFC4,RFC5,RHOH,STRADB,TGFB2,THBS1,TLR4,TRAF7,UBE2L3,UBE2N,UBE2S,WRAP53,XRCC5 |
| GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 2.0e-07 | 1139 | 220 | 22 | BRCA1,CCNF,CENPJ,CFAP20,EPHA3,FKBP4,GEN1,GPSM2,KIF11,MDM1,PLK1,POC1A,RANBP1,SKA3,SMC1A,SPAG5,SPICE1,STIL,STMN1,TACC3,TCTEX1D2,XRCC3 |
| GO_TRNA_MODIFICATION | 0.0e+00 | 3.0e-07 | 1139 | 86 | 14 | AARS2,ANKRD16,CDK5RAP1,CTU2,ELP6,GTPBP3,METTL2B,NSUN2,OSGEP,PUS3,SSB,TPRKB,TRMT10C,TRMT11 |
| GO_NCRNA_EXPORT_FROM_NUCLEUS | 0.0e+00 | 3.0e-07 | 1139 | 38 | 10 | NDC1,NOL6,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,SSB |
| GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 0.0e+00 | 3.0e-07 | 1139 | 203 | 21 | AKT1,APEX1,BRD7,CARM1,CCNE1,CDC45,DDX3X,E2F4,E2F8,EIF4G1,FAM83D,GTSE1,KIF14,LSM10,PAGR1,PIDD1,PRKDC,PSME3,SLFN11,TERT,TFDP1 |
| GO_MATURATION_OF_5_8S_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA | 0.0e+00 | 3.0e-07 | 1139 | 21 | 8 | ERI1,EXOSC2,EXOSC8,FTSJ3,RRS1,URB1,UTP20,WDR12 |
| GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 1139 | 61 | 12 | CAD,DCTPP1,DHODH,DTYMK,DUT,NEIL2,NME1,NTHL1,PRPS1,TDG,TYMS,UMPS |
| GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE | 0.0e+00 | 4.0e-07 | 1139 | 39 | 10 | MRPS26,MRPS9,PARP1,POLD1,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3 |
| GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | 0.0e+00 | 4.0e-07 | 1139 | 266 | 24 | AKT1,BARD1,CSE1L,ECT2,GTSE1,HEATR3,IPO4,KPNA3,NOL8,NUP107,NUP133,NUP155,NUP188,NUP35,NUP85,PARP1,PLK1,POLR1A,RRS1,SIN3A,SIX1,TERT,TRIM28,WRAP53 |
| GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER | 0.0e+00 | 4.0e-07 | 1139 | 188 | 20 | CAND1,ESR2,GTF2A2,GTF2F2,GTF2H3,HMGB1,MED20,MED4,NR4A2,PAXIP1,POLR2B,POLR2D,POLR2F,POLR2K,SUB1,TAF11,TAF5,TAF6L,TRIM28,WNT10B |
| GO_ATP_DEPENDENT_CHROMATIN_REMODELING | 0.0e+00 | 4.0e-07 | 1139 | 89 | 14 | CENPH,CENPI,CENPL,CENPS,CENPU,CENPX,HDAC2,HNRNPC,KNL1,MBD3,OIP5,POLE3,PTMA,SRCAP |
| GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_I_PROMOTER | 0.0e+00 | 4.0e-07 | 1139 | 30 | 9 | CD3EAP,GTF2H3,POLR1A,POLR1B,POLR1C,POLR2F,POLR2K,TAF1B,TWISTNB |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 0.0e+00 | 4.0e-07 | 1139 | 289 | 25 | AKT1,ATAD5,BRCA1,CCAR2,CUL2,DDIAS,DDX3X,ELL3,FIGNL1,IL20RA,IVNS1ABP,MAGEA3,MLH1,MSH6,MYBBP1A,NOC2L,OPA1,PARP1,PRKDC,PRKRA,PTPN2,RRP8,RTKN2,TMEM109,TNFRSF1B |
| GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION | 0.0e+00 | 4.0e-07 | 1139 | 40 | 10 | GTF2H3,NTHL1,PARP1,POLD1,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3 |
| GO_FORMATION_OF_EXTRACHROMOSOMAL_CIRCULAR_DNA | 0.0e+00 | 5.0e-07 | 1139 | 15 | 7 | BLM,DNA2,EXO1,RTEL1,TERF2,XRCC3,XRCC5 |
| GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 0.0e+00 | 4.0e-07 | 1139 | 63 | 12 | CD3EAP,H1-3,MACROH2A1,MYBBP1A,PABPC1L,POLR1A,POLR1B,POLR1C,POLR2F,POLR2K,TAF1B,TWISTNB |
| GO_RESPONSE_TO_TEMPERATURE_STIMULUS | 0.0e+00 | 5.0e-07 | 1139 | 249 | 23 | AKT1,ATR,CCAR2,DNAJA3,EIF2B1,EIF2B3,FKBP4,HDAC2,HSPD1,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLR2D,PSIP1,PTGES3,RPA1,RPA3,THBS1 |
| GO_REGULATION_OF_UBIQUITIN_PROTEIN_TRANSFERASE_ACTIVITY | 0.0e+00 | 6.0e-07 | 1139 | 52 | 11 | BMI1,CDC20,DCUN1D4,DCUN1D5,FBXO5,FEM1A,MAD2L1,PLK1,UBE2L3,UBE2N,UBE2S |
| GO_TERMINATION_OF_RNA_POLYMERASE_I_TRANSCRIPTION | 0.0e+00 | 5.0e-07 | 1139 | 31 | 9 | CD3EAP,GTF2H3,POLR1A,POLR1B,POLR1C,POLR2F,POLR2K,TAF1B,TWISTNB |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 1139 | 1033 | 54 | ADCY3,AFMID,ATP5PF,CAD,DCTPP1,DHODH,DLAT,DTYMK,DUT,ENTPD2,FABP5,FLAD1,GART,GK5,GPD2,HPRT1,IMPDH1,IPPK,KHK,MTHFD2L,MTMR12,NDC1,NEIL2,NME1,NTHL1,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PAICS,PARP1,PDE4A,PDE7A,PFKM,PI4K2B,PPAT,PRPS1,PRPS2,PTDSS1,RPE,RRM2,SHPK,SLC25A13,STARD7,TDG,TK1,TYMS,UMPS,XYLB |
| GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_GAP_FILLING | 0.0e+00 | 7.0e-07 | 1139 | 23 | 8 | LIG1,POLD1,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3 |
| GO_RNA_METHYLATION | 0.0e+00 | 7.0e-07 | 1139 | 79 | 13 | FBL,FDXACB1,FTSJ3,GTPBP3,METTL2B,METTL3,MRM1,MRM2,NSUN2,TGS1,TRMT10C,TRMT11,ZC3H13 |
| GO_CELLULAR_RESPONSE_TO_HEAT | 0.0e+00 | 8.0e-07 | 1139 | 142 | 17 | ATR,CCAR2,FKBP4,HDAC2,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLR2D,PTGES3,RPA1,RPA3,THBS1 |
| GO_MITOCHONDRIAL_TRANSCRIPTION | 0.0e+00 | 8.0e-07 | 1139 | 16 | 7 | MRPL12,MTERF1,MTERF3,PPARGC1B,TEFM,TFAM,TWNK |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 8.0e-07 | 1139 | 1863 | 81 | AKT1,ARAP3,ARHGAP11A,ARHGEF39,ATAD5,ATR,BARD1,BLM,BRCA1,BRD7,BRIP1,C1QBP,CCAR2,CHUK,CMKLR1,DDIAS,DDX3X,DEPDC1B,DHX33,DNA2,ECT2,ELL3,EXO1,FAM83D,FARP2,FFAR4,FIGNL1,FKTN,HACD3,HDAC2,HMGB1,IL20RA,ING5,IRF3,IVNS1ABP,KIF14,LPAR4,MAGEA3,MAP3K7,MBD3,MRE11,NOC2L,OPA1,PARP1,PBK,PDE4A,PHB,PIDD1,PLEKHG2,PLEKHG3,PRDM15,PRKRA,PTPN2,RASGRP1,RFC2,RFC3,RFC4,RFC5,RHOH,RHOT2,RMI1,RPA1,RPA3,RRS1,RTKN2,SETD9,SH3BP1,SSRP1,SSX2IP,STMN1,SUPT16H,SYNGAP1,TAF11,TAF5,TGFB2,THBS1,TLR4,TRAF7,TTI1,UBE2N,USP10 |
| GO_SEXUAL_REPRODUCTION | 0.0e+00 | 8.0e-07 | 1139 | 847 | 47 | ADCY3,AKT1,ASF1B,ASPM,BRIP1,DDX3X,DND1,ELL3,FANCA,FANCC,FANCD2,FANCL,FBXO5,FIGNL1,FUT10,GGT2,GMCL1,H2AX,HDAC2,KHDRBS1,KNL1,MCM8,METTL3,MLH1,MLH3,MYBL1,MYCBP,NDC1,NSUN2,PABPC1L,PAFAH1B2,PAFAH1B3,PLK1,POC1A,PTTG1,RAD51C,RPL39L,SEPTIN12,SLIRP,SPIN4,STX2,SYCP1,TRIP13,TSGA10,TTK,TUBGCP3,UBAP2L |
| GO_CARBOHYDRATE_CATABOLIC_PROCESS | 0.0e+00 | 9.0e-07 | 1139 | 198 | 20 | AMY2A,ENOSF1,FUT1,FUT10,GK5,GPD2,KHK,NDC1,NEU3,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PFKM,RPE,XYLB |
| GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS | 0.0e+00 | 1.0e-06 | 1139 | 81 | 13 | ANAPC1,ANAPC10,ANAPC4,BUB1B,BUB3,CDC20,FBXO5,MAD2L1,PLK1,PSMD5,PSME3,PTTG1,UBE2S |
| GO_REPLICATION_FORK_PROCESSING | 0.0e+00 | 1.0e-06 | 1139 | 33 | 9 | BLM,CENPS,CENPX,DNA2,EME1,GEN1,MRE11,RTEL1,TONSL |
| GO_RESPONSE_TO_HORMONE | 0.0e+00 | 1.0e-06 | 1139 | 994 | 52 | ADCY3,ADIPOR2,AKT1,APEX1,BRCA1,BRIP1,CACYBP,CAD,CARM1,CCNE1,CDC5L,CHUK,DNAAF4,DNMT3B,EEF2K,EIF2B1,EIF2B3,EIF4E,ESR2,FKBP4,GGT2,GKAP1,GOT2,GPR173,H2AZ1,HNMT,KHK,LEF1,MBD3,NME1,NR4A2,OPA1,PAGR1,PARP1,PHB,PNPT1,PPARGC1B,PPAT,PRKAR2A,PRKDC,PSPH,PTPN2,RAB8A,SAFB,SAFB2,SIX1,SKP2,TGFB2,THBS1,TYMS,UBE2L3,WNT10B |
| GO_MAINTENANCE_OF_CELL_NUMBER | 0.0e+00 | 1.1e-06 | 1139 | 163 | 18 | ASPM,EIF4E,EIF4ENIF1,ELAVL1,FANCC,FANCD2,FUT10,GATA2,LEO1,METTL3,MTF2,POLR2B,POLR2D,POLR2F,POLR2K,SMC1A,TAF6L,ZC3H13 |
| GO_NEUROGENESIS | 0.0e+00 | 1.1e-06 | 1139 | 1625 | 73 | ADGRF1,AKT1,ASPM,CAPRIN2,CARM1,CDC20,CDK5RAP1,CHD7,CIT,DDX56,DHFR,DLL3,DLX1,DNAAF4,DNMT3B,ECT2,EEF2K,EIF2B1,EIF2B3,EIF4E,EIF4ENIF1,EIF4G1,ELL3,EPHA3,EPOP,FARP2,FBXO45,FKBP4,GATA2,GPR173,HDAC2,HMGB1,HOXA2,HPRT1,IFT172,KIF20B,LEF1,METTL3,MPP5,MYB,MYPN,NME1,NPTX1,NR4A2,NUP133,ONECUT2,OPA1,PER2,PLXNA1,PPP1CC,PRPF19,RAB8A,RTN4IP1,SCLT1,SEMA3G,SIN3A,SIX1,SLC1A3,SLC45A3,STMN1,SYNGAP1,TERT,TGFB2,TLR4,TNFRSF1B,TNFRSF21,WDR36,WDR5,WNT10B,XRCC2,XRCC5,YTHDF1,ZNF488 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 0.0e+00 | 1.1e-06 | 1139 | 82 | 13 | ATAD5,AUNIP,CCAR2,DDIAS,ELL3,FANCB,FBXO5,KLHL15,PARPBP,POLQ,RTEL1,SMCHD1,TERF2 |
| GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.1e-06 | 1139 | 282 | 24 | ADCY3,AFMID,ATP5PF,CAD,DHODH,DLAT,DTYMK,DUT,FLAD1,GART,HPRT1,IMPDH1,MTHFD2L,NME1,PAICS,PARP1,PPAT,PRPS1,PRPS2,RRM2,SLC25A13,TK1,TYMS,UMPS |
| GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING | 0.0e+00 | 1.1e-06 | 1139 | 82 | 13 | ATR,DCLRE1B,HNRNPC,MRE11,PARP1,PIF1,PTGES3,RPA1,RTEL1,TERF2,TERT,WRAP53,XRCC5 |
| GO_POSITIVE_REGULATION_OF_TRANSLATION | 0.0e+00 | 1.1e-06 | 1139 | 129 | 16 | C1QBP,CDK5RAP1,DDX3X,DHX29,ELAVL1,FASTKD2,FASTKD3,GUF1,KHDRBS1,METTL3,MRPS27,POLR2D,THBS1,TRMT10C,UQCC2,YTHDF1 |
| GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION | 0.0e+00 | 1.2e-06 | 1139 | 17 | 7 | DNA2,GINS1,GINS3,LIG1,POLA1,RFC3,RFC4 |
| GO_NUCLEOLAR_LARGE_RRNA_TRANSCRIPTION_BY_RNA_POLYMERASE_I | 0.0e+00 | 1.2e-06 | 1139 | 17 | 7 | CD3EAP,IPPK,MACROH2A1,NCL,NOL11,TAF1B,TCOF1 |
| GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_TRANSLATION | 0.0e+00 | 1.2e-06 | 1139 | 17 | 7 | C1QBP,CDK5RAP1,FASTKD2,FASTKD3,MRPS27,TRMT10C,UQCC2 |
| GO_RNA_CAPPING | 0.0e+00 | 1.2e-06 | 1139 | 34 | 9 | GTF2F2,GTF2H3,NCBP1,POLR2B,POLR2D,POLR2F,POLR2K,RNGTT,TGS1 |
| GO_GAMETE_GENERATION | 1.0e-07 | 1.2e-06 | 1139 | 698 | 41 | AKT1,ASF1B,ASPM,BRIP1,DDX3X,DND1,ELL3,FANCA,FANCC,FANCD2,FANCL,FBXO5,FIGNL1,GGT2,GMCL1,H2AX,KHDRBS1,KNL1,MCM8,METTL3,MLH1,MLH3,MYBL1,MYCBP,NDC1,NSUN2,PABPC1L,PAFAH1B2,PAFAH1B3,PLK1,POC1A,PTTG1,RAD51C,RPL39L,SEPTIN12,SLIRP,SPIN4,SYCP1,TRIP13,TSGA10,TTK |
| GO_METAPHASE_PLATE_CONGRESSION | 1.0e-07 | 1.4e-06 | 1139 | 57 | 11 | CDCA8,CENPE,CENPF,FAM83D,KIF14,KIF22,MLH1,NDC80,RRS1,SPAG5,SPICE1 |
| GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA | 1.0e-07 | 1.6e-06 | 1139 | 35 | 9 | BMS1,DHX37,HEATR1,NOL10,PWP2,RRS1,TBL3,UTP20,UTP3 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 1.0e-07 | 1.6e-06 | 1139 | 100 | 14 | ATR,BRCA1,CCAR2,FANCB,H2AX,HMGB1,PARP1,PAXIP1,PRKDC,SMCHD1,TIMELESS,TRIM28,UBE2N,WRAP53 |
| GO_REGULATION_OF_CELL_DIVISION | 1.0e-07 | 1.6e-06 | 1139 | 168 | 18 | AHCTF1,ASPM,BLM,CCP110,CENPV,CIT,E2F8,ECT2,KIF14,KIF18B,KIF20A,KIF20B,KIF23,PKP4,PLK1,PRDM15,PRPF40A,TGFB2 |
| GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_ENDONUCLEOLYTIC | 1.0e-07 | 1.6e-06 | 1139 | 71 | 12 | APEX1,CPSF3,ELAC2,EXO1,FEN1,POP5,RIDA,RNASEH1,RPP14,RRS1,TSEN54,UTP20 |
| GO_HOMOLOGOUS_CHROMOSOME_SEGREGATION | 1.0e-07 | 1.7e-06 | 1139 | 58 | 11 | BRIP1,CCNE1,FANCD2,MLH1,MLH3,MRE11,NDC1,PLK1,PTTG1,SYCP1,TRIP13 |
| GO_REGULATION_OF_CENTROSOME_CYCLE | 1.0e-07 | 1.7e-06 | 1139 | 58 | 11 | BRCA1,CCNF,CENPJ,GEN1,KIF11,MDM1,POC1A,RANBP1,SPICE1,STIL,XRCC3 |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 1.0e-07 | 1.8e-06 | 1139 | 987 | 51 | AKT1,APEX1,BARD1,CCAR2,CTSC,DNAAF4,DND1,EIF4G1,ELAVL1,EXOSC2,EXOSC8,FAM83D,FASTKD1,FASTKD3,FBXO22,HMGB1,HNRNPC,HNRNPR,HSPBP1,MAD2L1,MAP3K7,METTL3,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PAFAH1B2,PBK,PHB,PLK1,PNPT1,PSMD5,PSME3,RAB8A,RIDA,SERBP1,SGTA,SLIRP,SNRNP70,SVIP,SYNCRIP,TNFRSF1B,UBE2G2,UCHL5,UQCC2,USP10,WNT10B |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 1.0e-07 | 1.9e-06 | 1139 | 737 | 42 | ACOX2,AKT1,BARD1,C1QBP,CCAR2,CTSC,CYCS,DDX3X,DHODH,ECT2,EIF4G1,HMGB1,HSPD1,HSPE1,IL20RA,ING5,KHDC1,MYB,MYBBP1A,MYBL2,PARP1,PHB,PIDD1,PLEKHG2,PRELID1,PRKDC,PRKRA,PTPN2,RRP1B,SLFN11,SOX7,ST18,TFDP1,TGFB2,THBS1,TLR4,TNFRSF1B,TOMM22,TRAF7,UTP11,WNT10B,ZNF346 |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 1.0e-07 | 1.9e-06 | 1139 | 1716 | 75 | AKT1,ASPM,ATAD5,BIRC5,BMI1,BRCA1,BRD7,BRIP1,CARM1,CDC20,CDC7,CDCA7,CDCA7L,CDKN3,CHTOP,COPS9,DBF4B,DNAJA3,DNMT1,E2F4,EGR3,ELL3,FAM98A,FAM98B,FANCA,FANCL,FBXO5,FKTN,FXN,GATA2,HDAC2,HMGB1,HMGN1,IFT172,IL12RB1,IL7R,ING5,KIF14,KIF20B,LEF1,MYB,NACC1,NME1,P3H3,PAXBP1,PER2,PHB,PPP1CC,PRDX3,PRKDC,PRKRA,PTPN2,RBPMS2,RIDA,RPA3,RTKN2,SIX1,SKP2,SLC39A10,SOX7,ST18,TERT,TFDP1,TGFB2,THBS1,TLR4,TNFRSF13C,TNFRSF1B,TNFRSF21,TTK,UHRF1,UTP20,VHL,WNT10B,XRCC5 |
| GO_NUCLEOBASE_METABOLIC_PROCESS | 1.0e-07 | 2.0e-06 | 1139 | 36 | 9 | CAD,DHODH,GART,HPRT1,PAICS,PPAT,PRPS1,TYMS,UMPS |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 1.0e-07 | 2.1e-06 | 1139 | 1287 | 61 | AKT1,ARAP3,ARHGAP11A,ATP1B3,BIRC5,CEP192,CHTOP,CYCS,DDX3X,DEPDC1B,DNAJC24,ECT2,EPHA3,HACD3,HMGB1,HSPD1,HSPE1,KHDC1,KLRK1,KNL1,LEF1,MAGEA3,MCM2,MPHOSPH10,MSH6,OAS3,PGAM5,PIDD1,PKMYT1,PKP4,PLXNA1,PPARGC1B,PPP1R8,PPP2R3B,PPP6R3,PRDX3,PRELID1,PSME3,PTTG1,RABEP1,RANBP1,RANBP3,RASGRP1,RHOH,RPS6KA1,RRP1B,SH2D4A,SH3BP1,SLC39A10,SNRNP70,SOX7,SSBP1,ST18,SYNGAP1,TDG,TERF2,TGFB2,THBS1,UCHL5,UHRF1,VMA21 |
| GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 1.0e-07 | 2.2e-06 | 1139 | 408 | 29 | AKT1,ATAD5,BRCA1,CCAR2,CTSC,DDIAS,DDX3X,ELL3,FIGNL1,FXN,IL20RA,ING5,IVNS1ABP,MAGEA3,NOC2L,NR4A2,OPA1,PARP1,PRELID1,PRKRA,PSME3,PTPN2,RTKN2,ST18,STRADB,TERT,TFDP1,THBS1,TRAF7 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 1.0e-07 | 2.3e-06 | 1139 | 853 | 46 | AKT1,ASF1B,ASPM,BRIP1,DDX3X,DND1,ELL3,FANCA,FANCC,FANCD2,FANCL,FBXO5,FIGNL1,GGT2,GMCL1,H2AX,HDAC2,KHDRBS1,KNL1,MCM8,METTL3,MLH1,MLH3,MYBL1,MYCBP,NDC1,NSUN2,PABPC1L,PAFAH1B2,PAFAH1B3,PLK1,POC1A,PPAT,PRDX3,PTTG1,RAD51C,RPL39L,SEPTIN12,SLIRP,SPIN4,SYCP1,TEKT4,TGFB2,TRIP13,TSGA10,TTK |
| GO_HISTONE_EXCHANGE | 1.0e-07 | 2.4e-06 | 1139 | 60 | 11 | CENPH,CENPI,CENPL,CENPS,CENPU,CENPX,KNL1,OIP5,POLE3,PTMA,SRCAP |
| GO_PROTEIN_IMPORT | 1.0e-07 | 2.4e-06 | 1139 | 192 | 19 | AKT1,CHCHD4,CSE1L,ECT2,HEATR3,HSPD1,IPO4,KPNA3,NUP107,NUP133,NUP155,NUP188,NUP35,NUP85,TIMM17A,TIMM21,TIMM23,TOMM22,TRIM28 |
| GO_NUCLEOSIDE_METABOLIC_PROCESS | 1.0e-07 | 2.6e-06 | 1139 | 104 | 14 | APOBEC3B,CAD,DHODH,DTYMK,ERH,HPRT1,IMPDH1,NME1,OPA1,PPAT,PRPS1,PRPS2,TK1,UMPS |
| GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_I_PROMOTER | 1.0e-07 | 2.6e-06 | 1139 | 37 | 9 | CD3EAP,GTF2H3,POLR1A,POLR1B,POLR1C,POLR2F,POLR2K,TAF1B,TWISTNB |
| GO_CELL_PROJECTION_ORGANIZATION | 1.0e-07 | 2.8e-06 | 1139 | 1545 | 69 | ADGRF1,AKT1,ANLN,ATG3,CAPRIN2,CARM1,CCP110,CDC20,CDKN3,CENPJ,CEP152,CEP192,CEP41,CEP78,CFAP20,CFAP46,CLUAP1,DDX56,DHFR,DNAAF4,DNAAF5,E2F4,EEF2K,EPHA3,FAM98A,FBXO45,FKBP4,HAUS3,HAUS8,HDAC2,HMGB1,HOXA2,HPRT1,HYLS1,IFT172,KIF20B,KIF24,MYPN,NME1,NPTX1,NR4A2,NUP85,ONECUT2,OPA1,PLK1,PLXNA1,POC1A,RAB8A,RPGRIP1L,RTN4IP1,SCLT1,SEMA3G,SIN3A,SSX2IP,STMN1,SYNGAP1,TCTEX1D2,TEKT4,TMEM237,TNFRSF21,TSGA10,TUBA4A,TUBB4B,TUBG1,WDR34,WDR36,WDR5,WRAP73,YTHDF1 |
| GO_REGULATION_OF_CYTOKINESIS | 1.0e-07 | 2.7e-06 | 1139 | 89 | 13 | AHCTF1,CCP110,CENPV,CIT,E2F8,ECT2,KIF14,KIF20A,KIF20B,KIF23,PKP4,PLK1,PRPF40A |
| GO_REGULATION_OF_DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY | 1.0e-07 | 2.8e-06 | 1139 | 7 | 5 | DSCC1,RFC2,RFC3,RFC4,RFC5 |
| GO_VIRAL_GENE_EXPRESSION | 1.0e-07 | 2.8e-06 | 1139 | 194 | 19 | EIF3B,GTF2F2,LEF1,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,POLR2B,POLR2D,POLR2F,POLR2K,RRP1B,SPCS1,SSB,TAF11 |
| GO_RIBOSOME_ASSEMBLY | 1.0e-07 | 3.3e-06 | 1139 | 62 | 11 | C1QBP,DDX3X,DHX30,FASTKD2,MDN1,MRPL11,MRPS7,MRTO4,MTERF3,PWP2,RRS1 |
| GO_CHROMOSOME_LOCALIZATION | 2.0e-07 | 3.4e-06 | 1139 | 76 | 12 | CDCA8,CENPE,CENPF,DLGAP5,FAM83D,KIF14,KIF22,MLH1,NDC80,RRS1,SPAG5,SPICE1 |
| GO_MITOCHONDRIAL_TRANSPORT | 2.0e-07 | 3.4e-06 | 1139 | 258 | 22 | ATP5PF,CHCHD4,HSPD1,IMMP1L,LETM1,MRPL18,OPA1,PNPT1,RHOT2,SAE1,SFXN2,SLC25A13,TFDP1,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,UBE2L3 |
| GO_REGULATION_OF_MITOCHONDRIAL_GENE_EXPRESSION | 2.0e-07 | 3.3e-06 | 1139 | 28 | 8 | C1QBP,CDK5RAP1,FASTKD2,FASTKD3,MRPS27,TRMT10C,TSFM,UQCC2 |
| GO_REGULATION_OF_MRNA_PROCESSING | 2.0e-07 | 3.6e-06 | 1139 | 141 | 16 | BARD1,C1QBP,CPSF4,IWS1,KHDRBS1,LEO1,NCBP1,NCL,PRPF19,SAFB,SAFB2,SF3B4,SFSWAP,SNRNP70,SRSF10,SRSF9 |
| GO_RIBONUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS | 2.0e-07 | 3.6e-06 | 1139 | 50 | 10 | CAD,DHODH,GART,HPRT1,IMPDH1,PAICS,PPAT,PRPS1,PRPS2,UMPS |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 2.0e-07 | 3.8e-06 | 1139 | 1220 | 58 | ANAPC4,ANLN,ARPC1A,ATR,BRCA1,BRD7,C1QBP,CAND1,CAPRIN2,CCP110,CDC20,CENPJ,CHTOP,DDX56,DHX33,DLGAP5,DNMT1,DNMT3B,EED,EEF2K,EIF4G1,EPHA3,FAM98A,FEN1,GATA2,GPSM2,GTF2H3,ICE1,IL1RAP,MACROH2A1,MIEF1,MRE11,MTF2,MYB,NME1,OPA1,PARP1,PAXBP1,PAXIP1,PLXNA1,POC1A,RANBP1,RPA1,RPA3,RTEL1,SAE1,SIN3A,SMC5,SPAG5,TFDP1,TGFB2,TLR4,TRIM28,UBE2L3,UBE2N,WNT10B,WRAP73,XRCC5 |
| GO_MEMBRANE_DOCKING | 2.0e-07 | 3.9e-06 | 1139 | 179 | 18 | CCP110,CENPJ,CEP152,CEP192,CEP41,CEP78,HAUS3,HAUS8,KIF24,PLK1,RAB8A,RPGRIP1L,SCFD2,SCLT1,STX2,TUBA4A,TUBB4B,TUBG1 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 2.0e-07 | 4.0e-06 | 1139 | 928 | 48 | AKT1,ASPM,CAPRIN2,CARM1,CDC20,CDK5RAP1,CHD7,CTSC,DDX56,DLL3,DLX1,DNMT3B,ECT2,EEF2K,EIF4E,EIF4ENIF1,EIF4G1,ELL3,EPHA3,FKBP4,GATA2,GPR173,HDAC2,HOXA2,IL1RAP,KIF14,KIF20B,MYB,NME1,OPA1,PER2,PLXNA1,PPP1CC,PRPF19,RTN4IP1,SEMA3G,SIN3A,SIX1,SLC45A3,SYNGAP1,TERT,TNFRSF1B,TNFRSF21,WDR36,XRCC2,XRCC5,YTHDF1,ZNF488 |
| GO_ERROR_FREE_TRANSLESION_SYNTHESIS | 2.0e-07 | 4.1e-06 | 1139 | 20 | 7 | RFC2,RFC3,RFC4,RFC5,RPA1,RPA3,SPRTN |
| GO_ERROR_PRONE_TRANSLESION_SYNTHESIS | 2.0e-07 | 4.1e-06 | 1139 | 20 | 7 | POLE2,RFC2,RFC3,RFC4,RFC5,RPA1,RPA3 |
| GO_PYRIMIDINE_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS | 2.0e-07 | 4.1e-06 | 1139 | 20 | 7 | DCTPP1,DTYMK,DUT,NEIL2,NTHL1,TDG,TYMS |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 2.0e-07 | 4.4e-06 | 1139 | 423 | 29 | ADCY3,ATP5PF,CAD,DHODH,DLAT,GART,HPRT1,IMPDH1,NDC1,NME1,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PAICS,PARP1,PDE4A,PDE7A,PFKM,PPAT,PRPS1,PRPS2,SLC25A13,UMPS |
| GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 2.0e-07 | 4.7e-06 | 1139 | 655 | 38 | ADCY3,AKT1,BMI1,CDC20,CENPE,CKS1B,CKS2,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DSCC1,ECT2,HACD3,HMGN1,KIF14,MAP3K7,MRE11,NCAPG2,PLK1,PRKAR2A,PTGES3,RASGRP1,RFC2,RFC3,RFC4,RFC5,STRADB,TGFB2,THBS1,TLR4,TRAF7,UBE2L3,UBE2N,UBE2S,WRAP53,XRCC5 |
| GO_RESPONSE_TO_IONIZING_RADIATION | 2.0e-07 | 4.7e-06 | 1139 | 144 | 16 | ATR,BLM,BRCA1,DNMT3B,ECT2,FANCD2,FIGNL1,H2AX,PARP1,PAXIP1,POLE3,PRKDC,TICRR,TMEM109,XRCC2,XRCC5 |
| GO_CENTRIOLE_ASSEMBLY | 2.0e-07 | 5.0e-06 | 1139 | 40 | 9 | BRCA1,CCP110,CENPJ,CEP152,E2F4,MDM1,SASS6,SPICE1,STIL |
| GO_REGULATION_OF_HISTONE_MODIFICATION | 3.0e-07 | 5.6e-06 | 1139 | 146 | 16 | BRCA1,BRD7,CHTOP,DNMT1,DNMT3B,EED,GATA2,IWS1,MACROH2A1,MTF2,MYB,NOC2L,PAXBP1,PAXIP1,SIN3A,UBE2N |
| GO_POSITIVE_REGULATION_OF_DNA_REPAIR | 3.0e-07 | 6.0e-06 | 1139 | 66 | 11 | BRCA1,FANCB,H2AX,HMGB1,PARP1,PRKDC,SMCHD1,TIMELESS,TRIM28,UBE2N,WRAP53 |
| GO_MICROTUBULE_NUCLEATION_BY_MICROTUBULE_ORGANIZING_CENTER | 3.0e-07 | 6.9e-06 | 1139 | 8 | 5 | CEP192,MZT1,TUBGCP3,TUBGCP4,TUBGCP5 |
| GO_TRNA_3_END_PROCESSING | 3.0e-07 | 6.9e-06 | 1139 | 8 | 5 | ELAC2,POLR3K,PTCD1,SSB,TRMT10C |
| GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION | 4.0e-07 | 7.6e-06 | 1139 | 114 | 14 | CENPJ,CEP192,FBXO5,FKBP4,KIF18B,KIF24,KIF2A,MZT1,SKA3,STMN1,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5 |
| GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION | 4.0e-07 | 7.8e-06 | 1139 | 42 | 9 | BRCA1,CHTOP,DNMT1,DNMT3B,EED,MTF2,MYB,PAXBP1,PAXIP1 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 4.0e-07 | 8.1e-06 | 1139 | 564 | 34 | ACOX2,AKT1,ATR,CHCHD4,CSE1L,ECT2,HEATR3,HSPD1,IMMP1L,IPO4,KPNA3,MACROH2A1,NUP107,NUP133,NUP155,NUP188,NUP35,NUP85,SAE1,SGTA,SPCS1,TERT,TFDP1,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,TRIM28,UBE2L3,WRAP53 |
| GO_REGULATION_OF_HISTONE_METHYLATION | 4.0e-07 | 8.1e-06 | 1139 | 68 | 11 | BRCA1,CHTOP,DNMT1,DNMT3B,EED,IWS1,MACROH2A1,MTF2,MYB,PAXBP1,PAXIP1 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 4.0e-07 | 8.0e-06 | 1139 | 1721 | 73 | ADCY3,ADIPOR2,AKT1,APEX1,BLM,BRCA1,BRIP1,CACYBP,CAD,CARM1,CCNE1,CDC5L,CHUK,DLX1,DNAAF4,DNMT1,DNMT3B,EEF2K,EGR3,EIF2B1,EIF2B3,EIF4E,EME1,ESR2,FKBP4,GGT2,GKAP1,GOT2,GPR173,GTF2F2,H2AZ1,HDAC2,HNMT,KHK,LEF1,MAP3K7,MBD3,NCBP1,NCL,NME1,NR4A2,ONECUT2,OPA1,PAGR1,PARP1,PHB,PNPT1,POLR2B,POLR2D,POLR2F,POLR2K,PPARGC1B,PPAT,PRKAR2A,PRKDC,PSPH,PTPN2,RAB8A,RBPMS2,SAFB,SAFB2,SIN3A,SIX1,SKP2,SMC1A,TGFB2,THBS1,TIMELESS,TLR4,TRIM41,TYMS,UBE2L3,WNT10B |
| GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 4.0e-07 | 8.5e-06 | 1139 | 83 | 12 | ELL3,GTF2F2,GTF2H3,IWS1,LEO1,NCBP1,POLR2B,POLR2D,POLR2F,POLR2K,SSRP1,SUPT16H |
| GO_CYTOKINESIS | 4.0e-07 | 8.7e-06 | 1139 | 170 | 17 | AHCTF1,ANLN,CCP110,CENPV,CIT,E2F8,ECT2,KIF14,KIF20A,KIF20B,KIF23,KIF4A,PKP4,PLK1,PRPF40A,SEPTIN12,STMN1 |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 4.0e-07 | 8.7e-06 | 1139 | 955 | 48 | AKT1,ASPM,C1QBP,CAPRIN2,CARM1,CDC20,CDK5RAP1,CHD7,DDX56,DLL3,DLX1,DNMT3B,ECT2,EEF2K,EIF4E,EIF4ENIF1,EIF4G1,ELL3,EPHA3,FBXO22,FKBP4,GATA2,GPR173,HDAC2,HOXA2,KIF14,KIF20B,MYB,NME1,OPA1,PER2,PLXNA1,PPP1CC,PRPF19,RTN4IP1,SEMA3G,SIN3A,SIX1,SLC45A3,SYNGAP1,TERT,TNFRSF1B,TNFRSF21,WDR36,XRCC2,XRCC5,YTHDF1,ZNF488 |
| GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | 4.0e-07 | 8.8e-06 | 1139 | 133 | 15 | ATAD5,ATR,BRCA1,CARM1,CDC5L,E2F4,E2F8,GTSE1,PAXIP1,PIDD1,PLK1,PRKDC,PRPF19,TFDP1,USP10 |
| GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 4.0e-07 | 8.9e-06 | 1139 | 231 | 20 | AKT1,ATAD5,BRCA1,CCAR2,DDIAS,DDX3X,ELL3,FIGNL1,FXN,IVNS1ABP,MAGEA3,NOC2L,NR4A2,OPA1,PRELID1,PSME3,RTKN2,STRADB,TERT,THBS1 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 4.0e-07 | 9.2e-06 | 1139 | 1135 | 54 | ADCY3,AKT1,APEX1,BLM,BRCA1,BRIP1,CACYBP,CAD,CARM1,CDC5L,CHUK,DDI2,DHFR,DHODH,DHX15,DNMT1,DNMT3B,EEF2K,EFTUD2,EIF2B1,EIF2B3,ERLIN1,FOXRED2,GKAP1,GOT2,GPR173,HDAC2,HNMT,HPRT1,IRF3,KHK,NME1,NR4A2,OPA1,PARP1,PNPT1,PPARGC1B,PPAT,PRKAR2A,PRKDC,PTPN2,RAB8A,RNF121,SGTA,SIN3A,SIX1,SRSF9,SVIP,TIMELESS,TLR4,TRIM41,TYMS,UBE2G2,WNT10B |
| GO_REGULATION_OF_CENTROSOME_DUPLICATION | 4.0e-07 | 9.4e-06 | 1139 | 43 | 9 | BRCA1,CCNF,CENPJ,GEN1,MDM1,POC1A,SPICE1,STIL,XRCC3 |
| GO_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_I | 5.0e-07 | 9.5e-06 | 1139 | 32 | 8 | DHX33,HEATR1,IPPK,MACROH2A1,NCL,NOL11,POLR2K,WDR75 |
| GO_RESPONSE_TO_LIPID | 5.0e-07 | 9.6e-06 | 1139 | 930 | 47 | ADCY3,AKT1,BRCA1,CAD,CARM1,CCNE1,CHUK,DNAAF4,DNMT3B,EIF4E,EPHA3,ESR2,FKBP4,GATA2,GGT2,H2AZ1,HDAC2,HMGB1,HNMT,HOXA2,IRF3,KLRK1,LEF1,MBD3,MYB,NME1,NR4A2,PAGR1,PARP1,PHB,PPARGC1B,PRDX3,PSPH,RIDA,SAFB,SAFB2,SHPK,SKP2,TGFB2,THBS1,TLR4,TNFRSF1B,TRIM41,TYMS,UBE2L3,WNT10B,XRCC5 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 5.0e-07 | 1.0e-05 | 1139 | 135 | 15 | BMI1,BRCA1,CDC20,CENPS,CENPX,DCUN1D4,DCUN1D5,HSPBP1,PAXIP1,PLK1,SKP2,SPRTN,UBE2L3,UBE2N,UBE2S |
| GO_PROTEIN_TARGETING_TO_MITOCHONDRION | 5.0e-07 | 1.1e-05 | 1139 | 101 | 13 | CHCHD4,HSPD1,IMMP1L,SAE1,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,UBE2L3 |
| GO_MITOTIC_SISTER_CHROMATID_COHESION | 6.0e-07 | 1.1e-05 | 1139 | 23 | 7 | CDC20,DSCC1,HASPIN,MACROH2A1,SGO1,SMC1A,SMC5 |
| GO_DNA_UNWINDING_INVOLVED_IN_DNA_REPLICATION | 6.0e-07 | 1.2e-05 | 1139 | 15 | 6 | BLM,MCM2,MCM6,RPA1,SSBP1,TWNK |
| GO_MITOTIC_DNA_REPLICATION | 6.0e-07 | 1.2e-05 | 1139 | 15 | 6 | CDC45,GINS1,LIG1,MCM2,MCM6,POLA1 |
| GO_POSITIVE_REGULATION_OF_UBIQUITIN_PROTEIN_TRANSFERASE_ACTIVITY | 6.0e-07 | 1.2e-05 | 1139 | 33 | 8 | BMI1,CDC20,DCUN1D4,DCUN1D5,PLK1,UBE2L3,UBE2N,UBE2S |
| GO_ATP_METABOLIC_PROCESS | 6.0e-07 | 1.3e-05 | 1139 | 303 | 23 | ATP5PF,BEND3,CYCS,FIGNL1,FXN,NDC1,NDUFA12,NDUFAB1,NUDT5,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PARG,PARP1,PFKM,SDHD,SLC25A13,TEFM,UQCC2 |
| GO_CELL_CYCLE_ARREST | 6.0e-07 | 1.3e-05 | 1139 | 237 | 20 | BARD1,BRCA1,CARM1,CDKN3,DDIAS,E2F4,E2F8,GTSE1,KIF20B,MYBBP1A,PIDD1,PNPT1,PPM1G,PPP2R3B,RRP8,STRADB,TFDP1,TGFB2,THBS1,WNT10B |
| GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 6.0e-07 | 1.3e-05 | 1139 | 156 | 16 | C1QBP,CDK5RAP1,DDX3X,DHX29,ELAVL1,FASTKD2,FASTKD3,GUF1,KHDRBS1,METTL3,MRPS27,POLR2D,THBS1,TRMT10C,UQCC2,YTHDF1 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 7.0e-07 | 1.3e-05 | 1139 | 942 | 47 | ANLN,ARPC1A,ATG3,ATR,BRCA1,CAND1,CCP110,CENPJ,DDX3X,DHX33,ECT2,EEF2K,EIF4G1,EPHA3,FAM98A,FARP2,FKBP4,GPSM2,GTF2H3,HEATR1,HMGB1,ICE1,IL1RAP,KIF14,MDM1,NCLN,PARP1,PLEKHG2,PLK1,RPA1,RPA3,RTEL1,SIX1,SMC1A,SPAG5,SPICE1,STIL,STMN1,SVIP,TCTEX1D2,TERF2,THBS1,TLR4,WDR75,WNT10B,WRAP73,XRCC5 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 7.0e-07 | 1.4e-05 | 1139 | 351 | 25 | AKT1,APEX1,CHUK,CYCS,DDX3X,DHFR,DNMT3B,ECT2,FANCC,FANCD2,FXN,HDAC2,LETM1,MYB,NCOA7,NR4A2,PARP1,PNPT1,PPARGC1B,PRDX3,PRKRA,SIN3A,TLR4,VKORC1L1,XRCC5 |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_CHECKPOINT | 7.0e-07 | 1.4e-05 | 1139 | 9 | 5 | CCAR2,GEN1,MAD2L1,NDC80,XRCC3 |
| GO_RESPONSE_TO_UV | 7.0e-07 | 1.5e-05 | 1139 | 139 | 15 | AKT1,ATR,CCAR2,COPS9,FEN1,HMGN1,METTL3,MSH6,NOC2L,PARP1,PBK,PCLAF,POLD1,SCARA3,SPRTN |
| GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION | 8.0e-07 | 1.5e-05 | 1139 | 34 | 8 | ATR,BLM,CDAN1,DONSON,FBXO5,SLFN11,TERF2,TIMELESS |
| GO_HEAD_DEVELOPMENT | 8.0e-07 | 1.5e-05 | 1139 | 774 | 41 | ASPM,ATP5PF,CCDC85C,CDK5RAP1,CENPF,CHD7,CLP1,DLX1,DMBX1,EIF2B3,FANCC,FANCD2,FBXO45,FUT10,GART,GATA2,GNB4,H2AX,HNMT,HOXA2,HPRT1,IFT172,KIF14,KLHL17,LEF1,MBD3,METTL3,NME1,NR4A2,PAFAH1B2,PAFAH1B3,PRKDC,RIDA,RPGRIP1L,SHROOM2,SIN3A,STIL,STMN1,TACC3,UTP3,XRCC5 |
| GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | 8.0e-07 | 1.7e-05 | 1139 | 199 | 18 | AKT1,APEX1,DND1,EIF4G1,ELAVL1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,HNRNPC,HNRNPR,METTL3,PNPT1,PSMD5,PSME3,RIDA,SERBP1,SYNCRIP |
| GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | 9.0e-07 | 1.8e-05 | 1139 | 141 | 15 | AKT1,CHCHD4,HSPD1,IMMP1L,SAE1,TFDP1,TIMM17A,TIMM21,TIMM22,TIMM23,TIMM29,TOMM22,TOMM5,TOMM70,UBE2L3 |
| GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_CELL_CYCLE_CHECKPOINT | 9.0e-07 | 1.8e-05 | 1139 | 74 | 11 | BRCA1,CARM1,CDC5L,E2F4,E2F8,GTSE1,PIDD1,PLK1,PRKDC,PRPF19,TFDP1 |
| GO_ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 9.0e-07 | 1.8e-05 | 1139 | 406 | 27 | CDCA8,CENPE,CENPF,CNIH3,CTSC,DLGAP5,FAM83D,GATA2,GPSM2,KIF14,KIF22,KIF23,LTV1,MAD2L1,MLH1,NDC80,OPA1,PLK1,PPP6R3,RASGRP1,RHOT2,RRS1,SEC23IP,SHROOM2,SPAG5,SPICE1,TMEM201 |
| GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | 9.0e-07 | 1.8e-05 | 1139 | 106 | 13 | BLM,CARM1,DONSON,E2F4,E2F8,EME1,GTSE1,MRE11,ORC1,PIDD1,PRKDC,TFDP1,TICRR |
| GO_POSITIVE_REGULATION_OF_CHROMATIN_ORGANIZATION | 9.0e-07 | 1.8e-05 | 1139 | 106 | 13 | BRCA1,BRD7,CHTOP,DNMT1,DNMT3B,EED,MTF2,MYB,PAXBP1,PAXIP1,SIN3A,TRIM28,UBE2N |
| GO_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS | 1.0e-06 | 1.9e-05 | 1139 | 35 | 8 | DCTPP1,DTYMK,DUT,NEIL2,NTHL1,RRM2,TDG,TYMS |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 1.0e-06 | 1.9e-05 | 1139 | 60 | 10 | AKT1,APEX1,CCNE1,CDC45,DDX3X,EIF4G1,FAM83D,LSM10,PAGR1,TERT |
| GO_CELLULAR_RESPONSE_TO_LIPID | 1.0e-06 | 1.9e-05 | 1139 | 615 | 35 | ADCY3,AKT1,BRCA1,CARM1,CCNE1,DNAAF4,DNMT3B,EIF4E,EPHA3,ESR2,FKBP4,H2AZ1,HDAC2,HMGB1,HOXA2,IRF3,KLRK1,LEF1,MYB,NME1,NR4A2,PAGR1,PARP1,PHB,PPARGC1B,SAFB,SAFB2,SHPK,SKP2,TLR4,TNFRSF1B,TRIM41,UBE2L3,WNT10B,XRCC5 |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 1.0e-06 | 2.0e-05 | 1139 | 671 | 37 | ADCY3,ATP5PF,B3GALNT1,B3GALNT2,C1GALT1,CAD,DHODH,DLAT,DTYMK,DUT,FAM20B,FKTN,FUT1,FUT10,GALNT14,GART,GK5,GNPNAT1,HPRT1,HS3ST2,HS3ST3A1,IMPDH1,NME1,PAICS,PARP1,POGLUT2,PPAT,PRPS1,PRPS2,RRM2,RXYLT1,SLC25A13,TK1,TYMS,UBE2G2,UMPS,XYLB |
| GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING | 1.0e-06 | 2.0e-05 | 1139 | 25 | 7 | BARD1,BLM,BRCA1,BRIP1,DNA2,MRE11,UBE2N |
| GO_HISTONE_MRNA_METABOLIC_PROCESS | 1.0e-06 | 2.0e-05 | 1139 | 25 | 7 | CPSF3,LSM10,NCBP1,SNRPD3,SNRPF,SNRPG,SSB |
| GO_SYNAPSIS | 1.0e-06 | 1.9e-05 | 1139 | 47 | 9 | BRIP1,CCNE1,FANCD2,MLH1,MLH3,MRE11,NDC1,SYCP1,TRIP13 |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 1.1e-06 | 2.1e-05 | 1139 | 960 | 47 | AKT1,ASPM,ATAD5,BIRC5,BMI1,CARM1,CDC20,CDC7,CDCA7L,CHTOP,COPS9,DBF4B,DNAJA3,DNMT1,EGR3,ELL3,FAM98A,FAM98B,FBXO5,FXN,GATA2,HDAC2,HMGB1,IL12RB1,IL7R,KIF14,KIF20B,LEF1,MYB,NACC1,NME1,PAXBP1,PPP1CC,PRDX3,PRKDC,RBPMS2,RTKN2,SIX1,SKP2,SLC39A10,TERT,TGFB2,THBS1,TLR4,TNFRSF13C,TTK,WNT10B |
| GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 1.2e-06 | 2.2e-05 | 1139 | 108 | 13 | ATR,DSCC1,HNRNPC,PIF1,PTGES3,RFC2,RFC3,RFC4,RFC5,TERF2,TFDP1,WRAP53,XRCC5 |
| GO_MICROTUBULE_NUCLEATION | 1.4e-06 | 2.7e-05 | 1139 | 26 | 7 | CENPJ,CEP192,MZT1,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 1.4e-06 | 2.6e-05 | 1139 | 624 | 35 | ANAPC4,ARPC1A,ATR,BRCA1,BRD7,CCP110,CENPJ,CHTOP,DLGAP5,DNMT1,DNMT3B,EED,FEN1,GPSM2,MACROH2A1,MIEF1,MRE11,MTF2,MYB,OPA1,PAXBP1,PAXIP1,POC1A,RANBP1,RTEL1,SAE1,SIN3A,SMC5,SPAG5,TFDP1,TRIM28,UBE2L3,UBE2N,WRAP73,XRCC5 |
| GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS | 1.5e-06 | 2.8e-05 | 1139 | 128 | 14 | APOBEC3B,CAD,DHODH,DTYMK,ERH,HPRT1,IMPDH1,NME1,OPA1,PPAT,PRPS1,PRPS2,TK1,UMPS |
| GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 1.5e-06 | 2.8e-05 | 1139 | 166 | 16 | AKT1,ATAD5,CCAR2,DDIAS,DDX3X,ELL3,FIGNL1,IL20RA,IVNS1ABP,MAGEA3,NOC2L,OPA1,PARP1,PRKRA,PTPN2,RTKN2 |
| GO_MITOCHONDRIAL_TRANSMEMBRANE_TRANSPORT | 1.6e-06 | 3.0e-05 | 1139 | 94 | 12 | ATP5PF,CHCHD4,HSPD1,LETM1,MRPL18,OPA1,PNPT1,SFXN2,SLC25A13,TIMM17A,TIMM21,TIMM23 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1.6e-06 | 3.0e-05 | 1139 | 1247 | 56 | ADCY3,AKT1,BMI1,BRCA1,BRD7,CAPRIN2,CDC20,CDCA2,CENPE,CENPS,CENPX,CHTOP,CKS1B,CKS2,DBF4,DBF4B,DCUN1D4,DCUN1D5,DDX3X,DHX33,DNMT1,DNMT3B,ECT2,EED,EIF4G1,FFAR4,HACD3,HDAC2,HMGB1,HSPBP1,KIF14,MAP3K7,MRE11,MTF2,MYB,NCAPG2,PAXBP1,PAXIP1,PHB,PLK1,PRKAR2A,RASGRP1,SKP2,SLC39A10,SPRTN,STRADB,SVIP,TGFB2,THBS1,TLR4,TRAF7,TTK,UBE2L3,UBE2N,UBE2S,XRCC5 |
| GO_NUCLEUS_ORGANIZATION | 1.8e-06 | 3.3e-05 | 1139 | 130 | 14 | AHCTF1,NDC1,NUP107,NUP133,NUP155,NUP35,PITPNB,PLK1,POLR1B,REEP4,SERBP1,SYCP1,VRK1,WRAP53 |
| GO_REGULATION_OF_TRANSLATIONAL_INITIATION | 1.8e-06 | 3.4e-05 | 1139 | 79 | 11 | DDX3X,DHX29,EIF2B1,EIF3B,EIF4G1,EIF5B,KHDRBS1,METTL3,NCBP1,POLR2D,YTHDF1 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 1.8e-06 | 3.3e-05 | 1139 | 1698 | 70 | ADCY3,AKT1,APEX1,BLM,BRCA1,BRIP1,CACYBP,CAD,CARM1,CDC5L,CHUK,DCPS,DHFR,DHODH,DNMT1,DNMT3B,ECT2,EEF2K,EFTUD2,EIF2B1,EIF2B3,EIF4E,EPHA3,FANCC,FXN,GGT2,GKAP1,GOT2,GPR173,H2AZ1,HDAC2,HMGB1,HNMT,HOXA2,IRF3,KHK,KLRK1,LRP5L,MBD3,MYB,NME1,NR4A2,OPA1,PARP1,PNPT1,PPARGC1B,PPAT,PRDX3,PRKAR2A,PRKDC,PSPH,PTPN2,RAB8A,RMI1,SELENOT,SHPK,SIN3A,SIX1,STX2,TGFB2,THBS1,TIMELESS,TLR4,TNFRSF1B,TRIM41,TWNK,TYMS,WNT10B,XRCC5,ZNF236 |
| GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY | 2.0e-06 | 3.7e-05 | 1139 | 96 | 12 | ACAD9,BCS1L,COA1,FASTKD3,LYRM7,NDUFA12,NDUFAB1,NDUFAF5,SDHAF3,TFAM,TIMM21,UQCC2 |
| GO_PROTEIN_SUMOYLATION | 2.3e-06 | 4.3e-05 | 1139 | 81 | 11 | KIAA1586,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,SAE1,TRIM28 |
| GO_DOUBLE_STRAND_BREAK_REPAIR_VIA_BREAK_INDUCED_REPLICATION | 2.5e-06 | 4.6e-05 | 1139 | 11 | 5 | CDC45,CDC7,MCM2,MCM5,MCM6 |
| GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 2.5e-06 | 4.6e-05 | 1139 | 98 | 12 | AKT1,ATAD5,CCAR2,DDIAS,DDX3X,ELL3,FIGNL1,IVNS1ABP,MAGEA3,NOC2L,OPA1,RTKN2 |
| GO_PURINE_NUCLEOBASE_BIOSYNTHETIC_PROCESS | 2.5e-06 | 4.6e-05 | 1139 | 11 | 5 | GART,HPRT1,PAICS,PPAT,PRPS1 |
| GO_DNA_MODIFICATION | 2.9e-06 | 5.3e-05 | 1139 | 117 | 13 | APEX1,APOBEC3B,BEND3,BRCA1,DNMT1,DNMT3B,GATAD2A,MBD3,NEIL2,NTHL1,PARP1,TDG,TRIM28 |
| GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION | 2.9e-06 | 5.3e-05 | 1139 | 19 | 6 | BLM,DONSON,FBXO5,SLFN11,TERF2,TIMELESS |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 3.0e-06 | 5.5e-05 | 1139 | 1823 | 73 | ADCY3,AKT1,BARD1,BLM,CAPRIN2,CCNE1,CCNF,CDCA2,CDK5RAP1,CDKN3,CENPE,CEP192,CKS1B,CKS2,COX11,DBF4,DBF4B,DDX3X,DHX33,ECT2,EEF2K,EIF4G1,FAM83D,FFAR4,FKTN,HACD3,HDAC2,HMGB1,KIF14,KNL1,MACROH2A1,MAP3K7,MPHOSPH10,MRE11,NCAPG2,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PARP1,PBK,PHB,PKMYT1,PLK1,PPARGC1B,PPP1R8,PPP2R3B,PPP6R3,PRDM15,PRDX3,PRKAR2A,PRKDC,PTGES3,PTPN2,RASGRP1,RHOH,RRP1B,SH2D4A,SLC39A10,STRADB,SYNGAP1,TGFB2,THBS1,TLR4,TRAF7,TTK,UBE2N,UQCC2,XRCC5 |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 3.1e-06 | 5.7e-05 | 1139 | 1825 | 73 | ADIPOR2,AKT1,ASPM,ATAD5,ATP5PF,BRCA1,C1QBP,CAPRIN2,CDC20,CHD7,CHUK,CMKLR1,DDX3X,DDX56,DHX33,DLX1,DNMT3B,ECT2,EEF2K,EGR3,EIF4G1,ELL3,EPHA3,FABP5,FAM49B,FBXO5,FFAR4,GATA2,HDAC2,HMGB1,HSPD1,IL12RB1,IL1RAP,IL7R,IRF3,KIF20B,KLRK1,LEF1,MACROH2A1,MAP3K7,MLH1,MRE11,MYB,NME1,OPA1,PARP1,PAXIP1,PER2,PLXNA1,POLR1C,POLR2F,POLR2K,POLR3B,POLR3G,POLR3H,POLR3K,PPARGC1B,PPP1CC,PRKDC,PRPF19,RASGRP1,RHOH,SIN3A,SIX1,TERT,TGFB2,THBS1,TLR4,TNFRSF1B,WNT10B,XRCC2,XRCC5,ZNF488 |
| GO_EMBRYO_DEVELOPMENT | 3.2e-06 | 5.9e-05 | 1139 | 1029 | 48 | AKT1,ASF1B,BRCA1,CENPU,CHD7,CHTOP,DLL3,DLX1,DNMT1,E2F8,FXN,GATA2,GINS1,GTPBP3,HDAC2,HIRA,HOXA2,IFT172,KIF20B,LEF1,LEO1,LRP5L,MBD3,MIXL1,NCAPG2,NSUN2,NUP133,PBX2,PHF6,POLG2,PRKDC,PRKRA,PRPF19,PSPH,RBPMS2,RPGRIP1L,SIN3A,SIX1,SLC39A3,SOX7,STIL,TCOF1,TDG,TGFB2,TOP1,TRIM28,WDR74,XRCC2 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 3.3e-06 | 5.9e-05 | 1139 | 649 | 35 | AKT1,ASF1B,BRCA1,CENPU,CHD7,CHTOP,DLL3,DLX1,E2F8,FXN,GATA2,GINS1,HOXA2,IFT172,KIF20B,LEF1,MBD3,NCAPG2,NSUN2,NUP133,PHF6,POLG2,PRKDC,PRPF19,PSPH,RPGRIP1L,SIN3A,SIX1,SLC39A3,STIL,TCOF1,TGFB2,TRIM28,WDR74,XRCC2 |
| GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 3.4e-06 | 6.1e-05 | 1139 | 540 | 31 | C1QBP,CHUK,DDX3X,GTF2F2,HACD3,HDAC2,HMGB1,HSPD1,IRF3,KLRK1,LEF1,MAP3K7,POLR2B,POLR2D,POLR2F,POLR2K,POLR3B,POLR3G,PPIH,PRKDC,PSMD5,PSME3,PSPC1,PVR,RASGRP1,RRP1B,SIN3A,TAF11,TLR4,UBE2N,XRCC5 |
| GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | 3.5e-06 | 6.3e-05 | 1139 | 41 | 8 | GTF2F2,LEF1,POLR2B,POLR2D,POLR2F,POLR2K,RRP1B,TAF11 |
| GO_PROTEIN_FOLDING | 3.6e-06 | 6.4e-05 | 1139 | 220 | 18 | CHCHD4,DNAJA3,DNAJC24,ENGASE,FKBP4,FUT10,GNB4,HSPA4L,HSPBP1,HSPD1,HSPE1,MLEC,PFDN1,PPIH,PPIL1,PTGES3,SGTA,SNRNP70 |
| GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 3.7e-06 | 6.7e-05 | 1139 | 974 | 46 | AKT1,ASF1B,ASPM,BRIP1,CBX2,CCNF,CENPI,CHD7,DND1,E2F8,ELL3,FANCA,FANCC,FBXO5,FKBP4,GATA2,GGT2,GMCL1,H2AX,KHDRBS1,KNL1,LEF1,METTL3,MLH1,MYBL1,MYCBP,NDC1,NSUN2,NUP107,PABPC1L,PAFAH1B2,PAFAH1B3,POC1A,PRDX3,PRKDC,PTTG1,RAD51C,RPL39L,SAFB2,SEPTIN12,SLIRP,SYCP1,TGFB2,TRIM28,TRIP13,TSGA10 |
| GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II | 3.8e-06 | 6.8e-05 | 1139 | 102 | 12 | AP2S1,CENPE,CTSE,HLA-DOB,KIF11,KIF15,KIF22,KIF23,KIF2A,KIF4A,KLC2,THBS1 |
| GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 3.8e-06 | 6.8e-05 | 1139 | 337 | 23 | AARS2,AFMID,ASNSD1,CAD,DARS2,ENOPH1,ENOSF1,GART,GCSH,GOT2,HNMT,LARS2,MARS2,MTHFD2L,NARS2,PPAT,PSMD5,PSME3,PSPH,RARS1,RIDA,SARS2,SLC1A3 |
| GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 3.8e-06 | 6.8e-05 | 1139 | 1189 | 53 | AKT1,BIRC5,BRCA1,CAPRIN2,CCAR2,CDK5RAP1,COPS9,DDX3X,DHFR,DNMT1,DNMT3B,EIF4E,EIF4ENIF1,EIF4G1,FBXO5,FKTN,HDAC2,HNRNPR,IVNS1ABP,LEF1,MACROH2A1,MAD2L1,MAGEA3,METTL3,MRPL13,MTF2,NCL,NCOA7,NOC2L,PBK,PER2,PHB,PLK1,PPP1R8,PRDM15,PRDX3,PRKAR2A,PRKDC,PRMT3,PTPN2,PTTG1,RIDA,RPS6KA1,SGTA,SIN3A,SNRNP70,SVIP,SYNCRIP,THBS1,TLR4,TYMS,UBE2G2,UCHL5 |
| GO_MICROTUBULE_NUCLEATION_BY_INTERPHASE_MICROTUBULE_ORGANIZING_CENTER | 3.9e-06 | 6.9e-05 | 1139 | 6 | 4 | MZT1,TUBGCP3,TUBGCP4,TUBGCP5 |
| GO_MRNA_5_SPLICE_SITE_RECOGNITION | 3.9e-06 | 6.9e-05 | 1139 | 6 | 4 | PRPF39,PSIP1,SFSWAP,SNRPC |
| GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 4.0e-06 | 7.1e-05 | 1139 | 30 | 7 | ATAD5,CDC7,DBF4B,FBXO5,RAD51C,SIN3A,WNT10B |
| GO_PYRIMIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 4.0e-06 | 7.1e-05 | 1139 | 55 | 9 | CAD,DHODH,DTYMK,DUT,NME1,PRPS1,TK1,TYMS,UMPS |
| GO_PURINE_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS | 4.1e-06 | 7.2e-05 | 1139 | 20 | 6 | GART,HPRT1,IMPDH1,PAICS,PPAT,PRPS2 |
| GO_RNA_5_END_PROCESSING | 4.1e-06 | 7.2e-05 | 1139 | 20 | 6 | PNPT1,POP5,RPP14,SSB,TRMT10C,UTP20 |
| GO_MITOCHONDRIAL_DNA_REPLICATION | 4.2e-06 | 7.4e-05 | 1139 | 12 | 5 | DNA2,DNAJA3,POLG2,SSBP1,TWNK |
| GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS | 4.2e-06 | 7.3e-05 | 1139 | 70 | 10 | DCTPP1,DUT,ENTPD2,HPRT1,NEIL2,NTHL1,NUDT5,PDE4A,PDE7A,TDG |
| GO_MONOSACCHARIDE_METABOLIC_PROCESS | 4.4e-06 | 7.8e-05 | 1139 | 292 | 21 | AKT1,COX11,CRTC2,DLAT,FABP5,FUT1,FUT10,GOT2,GPD2,KHK,NUDT5,PER2,PFKM,PGM5,PTPN2,RPE,SDHAF3,SLC25A13,SLC45A3,WDR5,XYLB |
| GO_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY | 4.6e-06 | 8.1e-05 | 1139 | 56 | 9 | BRCA1,CARM1,DNAAF4,ESR2,PAGR1,PARP1,PPARGC1B,SAFB,SKP2 |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 4.6e-06 | 8.0e-05 | 1139 | 468 | 28 | BRCA1,C1QBP,CHUK,DDX3X,DHX33,FAM49B,HDAC2,HMGB1,HSPD1,IL12RB1,IL1RAP,IRF3,KLRK1,MAP3K7,MRE11,MYB,POLR1C,POLR2F,POLR2K,POLR3B,POLR3G,POLR3H,POLR3K,PRKDC,RASGRP1,THBS1,TLR4,XRCC5 |
| GO_RESPONSE_TO_GAMMA_RADIATION | 4.6e-06 | 8.1e-05 | 1139 | 56 | 9 | ATR,FANCD2,H2AX,PARP1,POLE3,PRKDC,TMEM109,XRCC2,XRCC5 |
| GO_FEMALE_MEIOTIC_NUCLEAR_DIVISION | 5.1e-06 | 8.8e-05 | 1139 | 31 | 7 | FBXO5,MLH1,MLH3,PLK1,RAD51C,TRIP13,TTK |
| GO_GLYCOSYL_COMPOUND_BIOSYNTHETIC_PROCESS | 5.1e-06 | 8.7e-05 | 1139 | 43 | 8 | CAD,DHODH,DTYMK,HPRT1,IMPDH1,NME1,TK1,UMPS |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 5.1e-06 | 8.7e-05 | 1139 | 777 | 39 | APOBEC3B,C1QBP,CHUK,DDX3X,GTF2F2,HACD3,HDAC2,HMGB1,HSPD1,IL12RB1,IRF3,KLRK1,LEF1,MAP3K7,METTL3,OAS3,POLR2B,POLR2D,POLR2F,POLR2K,POLR3B,POLR3G,PPIH,PRKDC,PSMD5,PSME3,PSPC1,PTPN2,PVR,RASGRP1,RNF26,RRP1B,SIN3A,TAF11,TLR4,TRIM28,UBE2N,USP18,XRCC5 |
| GO_TRANSCRIPTION_PREINITIATION_COMPLEX_ASSEMBLY | 5.1e-06 | 8.7e-05 | 1139 | 43 | 8 | CAND1,GTF2A2,GTF3C5,HMGB1,TAF11,TAF1B,TAF6L,WNT10B |
| GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS | 5.4e-06 | 9.3e-05 | 1139 | 72 | 10 | ATR,HNRNPC,MRE11,PIF1,PTGES3,RPA1,TERF2,TERT,WRAP53,XRCC5 |
| GO_KINETOCHORE_ORGANIZATION | 5.6e-06 | 9.6e-05 | 1139 | 21 | 6 | CENPE,CENPF,CENPH,CENPS,CENPX,NDC80 |
| GO_RESPONSE_TO_CYTOKINE | 6.2e-06 | 1.1e-04 | 1139 | 1210 | 53 | ADIPOR2,AKT1,BIRC5,BOLA2,BRCA1,CA1,CACYBP,CDC5L,CHUK,CMKLR1,EED,GGT2,GNPNAT1,H3C1,HNMT,HNRNPDL,IL12RB1,IL1RAP,IL20RA,IL7R,IRF3,LEF1,MAP3K7,MCM2,METTL3,MTF2,MYBL2,NCL,NUP35,OAS3,PHB,PNPT1,PSMD5,PSME3,PTPN2,SHPK,SRM,ST18,STIP1,SYNCRIP,THBS1,TLR4,TNFRSF13C,TNFRSF1B,TNFRSF21,TUBA1B,TWISTNB,TYMS,UBE2G2,UBE2N,USP10,USP18,XRCC5 |
| GO_CIRCADIAN_RHYTHM | 6.3e-06 | 1.1e-04 | 1139 | 207 | 17 | CCAR2,EGR3,HDAC2,HNRNPR,HS3ST2,METTL3,MYBBP1A,PER2,PPP1CC,PRKDC,PSPC1,SIN3A,SUV39H1,SUV39H2,TIMELESS,TOP1,TYMS |
| GO_TELOMERE_MAINTENANCE_VIA_RECOMBINATION | 6.7e-06 | 1.1e-04 | 1139 | 13 | 5 | RAD51C,SMC5,SMC6,TERF2,XRCC3 |
| GO_CELLULAR_RESPIRATION | 6.9e-06 | 1.2e-04 | 1139 | 187 | 16 | CISD1,CYCS,DLAT,FXN,GPD2,IDH3A,LYRM7,MYBBP1A,NDUFA12,NDUFAB1,PNPT1,POLG2,PRELID1,SDHB,SDHD,SLC25A13 |
| GO_CELLULAR_RESPONSE_TO_RADIATION | 6.9e-06 | 1.2e-04 | 1139 | 187 | 16 | ATR,BLM,COPS9,ECT2,FIGNL1,H2AX,METAP1,METAP2,METTL3,NOC2L,PARP1,PBK,POLD1,POLE3,TMEM109,XRCC5 |
| GO_PYRIMIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | 7.2e-06 | 1.2e-04 | 1139 | 45 | 8 | CAD,DHODH,DTYMK,DUT,NME1,PRPS1,TYMS,UMPS |
| GO_RESPONSE_TO_OXIDATIVE_STRESS | 7.2e-06 | 1.2e-04 | 1139 | 453 | 27 | ACOX2,AKT1,APEX1,CHUK,CYCS,DHFR,ECT2,FANCC,FANCD2,FXN,HDAC2,MACROH2A1,MYB,NCOA7,NDUFA12,NR4A2,PARP1,PNPT1,PPARGC1B,PRDX3,PRKRA,PSIP1,SCARA3,SIN3A,STX2,TLR4,VKORC1L1 |
| GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 7.4e-06 | 1.2e-04 | 1139 | 278 | 20 | AKT1,CISD1,CYCS,DLAT,FXN,GPD2,IDH3A,KHK,LYRM7,MYBBP1A,NDUFA12,NDUFAB1,PER2,PNPT1,POLG2,PPP1CC,PRELID1,SDHB,SDHD,SLC25A13 |
| GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 7.4e-06 | 1.2e-04 | 1139 | 278 | 20 | BRCA1,C1QBP,CARM1,CCNE1,DNAAF4,ESR2,FABP5,FKBP4,IRF3,MAP3K7,NR4A2,PAGR1,PARP1,PHB,PPARGC1B,SAFB,SAFB2,SKP2,TLR4,UBE2N |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 7.4e-06 | 1.2e-04 | 1139 | 1000 | 46 | AKT1,ASPM,C1QBP,CAPRIN2,CARM1,CMKLR1,DDX56,DLX1,DNMT3B,ECT2,EEF2K,EGR3,EIF4G1,ELL3,EPHA3,FBXO5,GATA2,HDAC2,HMGB1,IL12RB1,IL7R,KIF20B,LEF1,MACROH2A1,MYB,NME1,OPA1,PA2G4,PARP1,PLXNA1,PPARGC1B,PPP1CC,PRPF19,RASGRP1,RHOH,RPS6KA1,SIN3A,TERT,TGFB2,TNFRSF1B,VEZF1,VHL,WNT10B,XRCC2,XRCC5,ZNF488 |
| GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_I | 7.5e-06 | 1.3e-04 | 1139 | 22 | 6 | DHX33,HEATR1,IPPK,NCL,NOL11,WDR75 |
| GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 7.7e-06 | 1.3e-04 | 1139 | 704 | 36 | ADCY3,ADIPOR2,AKT1,APEX1,BRCA1,BRIP1,CARM1,CCNE1,CDC5L,DNAAF4,DNMT3B,EEF2K,EIF4E,ESR2,FKBP4,GKAP1,GPR173,H2AZ1,LEF1,NR4A2,OPA1,PAGR1,PARP1,PHB,PPARGC1B,PPAT,PRKAR2A,PRKDC,PTPN2,RAB8A,SAFB,SAFB2,SIX1,SKP2,UBE2L3,WNT10B |
| GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS | 7.8e-06 | 1.3e-04 | 1139 | 75 | 10 | ATAD5,EXO1,HMGB1,HSPD1,LEF1,MLH1,MSH6,PAXIP1,POLQ,PRKDC |
| GO_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE | 8.0e-06 | 1.3e-04 | 1139 | 33 | 7 | BUB3,CENPE,ECT2,KNL1,NDC80,SGO1,SPAG5 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 8.1e-06 | 1.3e-04 | 1139 | 973 | 45 | ADCY3,AKT1,APEX1,BLM,BRCA1,CAD,CARM1,CCNE1,CDC5L,DHFR,DHODH,DNAAF4,DNMT3B,EEF2K,EFTUD2,EIF4E,ESR2,FKBP4,GGT2,GOT2,H2AZ1,HDAC2,HNMT,IRF3,LEF1,MBD3,NME1,NR4A2,OPA1,PAGR1,PARP1,PHB,PNPT1,PPARGC1B,PSPH,SAFB,SAFB2,SIN3A,SIX1,SKP2,TGFB2,THBS1,TYMS,UBE2L3,WNT10B |
| GO_HISTONE_H3_ACETYLATION | 8.3e-06 | 1.4e-04 | 1139 | 60 | 9 | BRCA1,CRTC2,ING5,LEF1,MAP3K7,POLE3,SIN3A,TAF6L,WDR5 |
| GO_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 8.6e-06 | 1.4e-04 | 1139 | 129 | 13 | BRCA1,CARM1,CCNE1,DNAAF4,ESR2,FKBP4,PAGR1,PARP1,PHB,PPARGC1B,SAFB,SAFB2,SKP2 |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 8.7e-06 | 1.4e-04 | 1139 | 594 | 32 | ADCY3,AFMID,ATP5PF,CAD,DHODH,DLAT,DTYMK,DUT,FABP5,FLAD1,GART,GK5,HPRT1,IMPDH1,IPPK,MTHFD2L,MTMR12,NME1,PAICS,PARP1,PI4K2B,PPAT,PRPS1,PRPS2,PTDSS1,RRM2,SLC25A13,STARD7,TK1,TYMS,UMPS,XYLB |
| GO_MICROTUBULE_POLYMERIZATION | 8.9e-06 | 1.5e-04 | 1139 | 76 | 10 | CENPJ,CEP192,FBXO5,FKBP4,MZT1,STMN1,TUBG1,TUBGCP3,TUBGCP4,TUBGCP5 |
| GO_POSITIVE_REGULATION_OF_SPINDLE_CHECKPOINT | 8.9e-06 | 1.5e-04 | 1139 | 7 | 4 | GEN1,MAD2L1,NDC80,XRCC3 |
| GO_PYRIMIDINE_DEOXYRIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS | 8.9e-06 | 1.5e-04 | 1139 | 7 | 4 | DCTPP1,DTYMK,DUT,TYMS |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 9.5e-06 | 1.5e-04 | 1139 | 1454 | 60 | ADCY3,ADIPOR2,AKT1,APEX1,BLM,BRCA1,BRIP1,CAD,CARM1,CCNE1,CDC5L,DLX1,DNAAF4,DNMT1,DNMT3B,EEF2K,EGR3,EIF4E,EME1,ESR2,FKBP4,GKAP1,GPR173,GTF2F2,H2AZ1,HDAC2,LEF1,MAP3K7,NCBP1,NCL,NR4A2,ONECUT2,OPA1,PAGR1,PARP1,PHB,POLR2B,POLR2D,POLR2F,POLR2K,PPARGC1B,PPAT,PRKAR2A,PRKDC,PTPN2,RAB8A,RBPMS2,SAFB,SAFB2,SIN3A,SIX1,SKP2,SMC1A,TGFB2,THBS1,TIMELESS,TLR4,TRIM41,UBE2L3,WNT10B |
| GO_RIBOSE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 9.7e-06 | 1.6e-04 | 1139 | 192 | 16 | ADCY3,ATP5PF,CAD,DHODH,DLAT,GART,HPRT1,IMPDH1,NME1,PAICS,PARP1,PPAT,PRPS1,PRPS2,SLC25A13,UMPS |
| GO_NUCLEAR_PORE_ORGANIZATION | 1.0e-05 | 1.7e-04 | 1139 | 14 | 5 | AHCTF1,NDC1,NUP107,NUP133,NUP35 |
| GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS | 1.0e-05 | 1.6e-04 | 1139 | 23 | 6 | CAD,DCTPP1,DTYMK,DUT,NME1,TYMS |
| GO_PYRIMIDINE_NUCLEOTIDE_CATABOLIC_PROCESS | 1.0e-05 | 1.7e-04 | 1139 | 14 | 5 | DCTPP1,DUT,NEIL2,NTHL1,TDG |
| GO_DNA_METHYLATION_OR_DEMETHYLATION | 1.1e-05 | 1.8e-04 | 1139 | 95 | 11 | APEX1,APOBEC3B,BEND3,BRCA1,DNMT1,DNMT3B,GATAD2A,MBD3,PARP1,TDG,TRIM28 |
| GO_MULTI_ORGANISM_LOCALIZATION | 1.1e-05 | 1.8e-04 | 1139 | 62 | 9 | KPNA3,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85 |
| GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | 1.1e-05 | 1.8e-04 | 1139 | 78 | 10 | HNRNPR,LEO1,METTL3,NCBP1,NCL,PNPT1,PRPF19,RIDA,SF3B4,SNRNP70 |
| GO_PROTEIN_MATURATION | 1.1e-05 | 1.7e-04 | 1139 | 285 | 20 | ATP23,BOLA2,CHCHD4,CTSE,DDI2,FXN,GCSH,GLRX5,HSPD1,IFT172,IMMP1L,MAGEA3,METAP2,NDUFAB1,PARP1,PIDD1,SPCS1,THBS1,TIMM17A,YAE1 |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1.1e-05 | 1.7e-04 | 1139 | 463 | 27 | ADCY3,ATP5PF,DLAT,GART,HPRT1,IMPDH1,MTHFD2L,NDC1,NME1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,OPA1,PAICS,PARP1,PDE4A,PDE7A,PFKM,PPAT,PRPS1,PRPS2,SLC16A9,SLC25A13 |
| GO_NEGATIVE_REGULATION_OF_DNA_REPAIR | 1.2e-05 | 1.9e-04 | 1139 | 35 | 7 | AUNIP,FANCB,KLHL15,PARPBP,POLQ,SMCHD1,TERF2 |
| GO_RESPONSE_TO_LIGHT_STIMULUS | 1.2e-05 | 1.9e-04 | 1139 | 311 | 21 | AKT1,ATR,CCAR2,COPS9,FEN1,HMGN1,METAP1,METAP2,METTL3,MSH6,NOC2L,PARP1,PBK,PCLAF,PER2,POLD1,PPP1CC,SCARA3,SLC1A3,SPRTN,SYNGAP1 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 1.2e-05 | 2.0e-04 | 1139 | 440 | 26 | ACOX2,AFMID,AKT1,ALDH1B1,APOBEC3B,ECHDC1,ENOSF1,ENTPD2,ENTPD6,FUT1,FUT10,GCSH,GK5,GOT2,GPD2,HNMT,HPRT1,KHK,MCAT,NUDT5,PFKM,PPAT,RIDA,RPE,SLC25A17,XYLB |
| GO_MEIOTIC_CHROMOSOME_SEPARATION | 1.3e-05 | 2.1e-04 | 1139 | 24 | 6 | CENPS,CENPX,EME1,MLH1,RMI1,TTK |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1.3e-05 | 2.1e-04 | 1139 | 1703 | 67 | AJAP1,AKT1,ATAD5,AUNIP,BRCA1,C1QBP,CCAR2,DDIAS,DDX3X,DLL3,DLX1,ELL3,FANCB,FBXO5,FEM1A,FFAR4,FIGNL1,FKTN,FXN,GATA2,IL7R,IVNS1ABP,KLHL15,KLRK1,KREMEN2,MAGEA1,MAGEA3,METTL3,MMRN2,NCOA7,NOC2L,NR4A2,ONECUT2,OPA1,PARPBP,PBK,PHB,POLQ,PRDM15,PRELID1,PRKDC,PSMD5,PSME3,PTPN2,RBPMS2,RHOH,RNF26,RPGRIP1L,RTEL1,RTKN2,SEMA3G,SGTA,SH3BP1,SMCHD1,STMN1,STRADB,SVIP,SYNGAP1,TERF2,TERT,TGFB2,THBS1,TLR4,TNFRSF1B,UBE2G2,USP10,VHL |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 1.3e-05 | 2.1e-04 | 1139 | 1670 | 66 | AKT1,ARPC1A,ATAD5,C1QBP,C7,CHUK,CMKLR1,CTSC,DNAJA3,EGR3,EIF2B1,EIF2B3,FAM49B,FANCA,FANCD2,GATA2,GGT2,H3C1,HLA-DOB,HMGB1,HSPD1,ICAM5,IL12RB1,IL7R,IRF3,KLRK1,LEF1,LEO1,MAP3K7,METTL3,MIXL1,MLH1,MYB,NCAPG2,NFATC3,NME1,PAXIP1,PHB,POLR3B,POLR3G,PPARGC1B,PRELID1,PRKDC,PSMD5,PSME3,PSPC1,PTPN2,PVR,RASGRP1,RBBP5,RHOH,RNF26,SHPK,SIN3A,SLC39A10,TGFB2,THBS1,TLR4,TNFRSF13C,TNFRSF1B,TNFRSF21,UBE2N,USP18,WDR5,XRCC5,YTHDF1 |
| GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS_VIA_GERMLINE_RECOMBINATION_WITHIN_A_SINGLE_LOCUS | 1.3e-05 | 2.0e-04 | 1139 | 63 | 9 | ATAD5,EXO1,HMGB1,HSPD1,LEF1,MLH1,MSH6,PAXIP1,PRKDC |
| GO_PYRIMIDINE_NUCLEOSIDE_METABOLIC_PROCESS | 1.5e-05 | 2.3e-04 | 1139 | 36 | 7 | APOBEC3B,CAD,DHODH,DTYMK,ERH,TK1,UMPS |
| GO_HISTONE_H3_K9_MODIFICATION | 1.6e-05 | 2.5e-04 | 1139 | 50 | 8 | BEND3,BRCA1,CRTC2,DNMT1,DNMT3B,MYB,SUV39H1,SUV39H2 |
| GO_POSITIVE_REGULATION_OF_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | 1.6e-05 | 2.5e-04 | 1139 | 50 | 8 | AKT1,APEX1,CCNE1,CDC45,DDX3X,EIF4G1,LSM10,TERT |
| GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 1.6e-05 | 2.5e-04 | 1139 | 157 | 14 | AKT1,CISD1,KHK,NDC1,NUP107,NUP133,NUP155,NUP160,NUP188,NUP35,NUP85,PNPT1,PRELID1,UQCC2 |
| GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS | 1.8e-05 | 2.9e-04 | 1139 | 248 | 18 | BRCA1,CARM1,CCNE1,DNAAF4,DNMT3B,EIF4E,ESR2,FKBP4,LEF1,NR4A2,PAGR1,PARP1,PHB,PPARGC1B,SAFB,SAFB2,SKP2,UBE2L3 |
| GO_POSITIVE_REGULATION_OF_DNA_REPLICATION | 1.8e-05 | 2.8e-04 | 1139 | 37 | 7 | ATAD5,CACYBP,CDC7,DBF4,DBF4B,DNA2,E2F8 |
| GO_REGULATION_OF_HEMOPOIESIS | 1.8e-05 | 2.8e-04 | 1139 | 477 | 27 | EGR3,FANCA,FANCD2,GATA2,H3C1,HMGB1,IL12RB1,IL7R,LEF1,LEO1,METTL3,MIXL1,MYB,NCAPG2,NME1,PPARGC1B,PRELID1,PSMD5,PSME3,PTPN2,RASGRP1,RBBP5,RHOH,SIN3A,THBS1,TLR4,WDR5 |
| GO_MALE_GAMETE_GENERATION | 1.9e-05 | 3.0e-04 | 1139 | 562 | 30 | ASF1B,ASPM,BRIP1,ELL3,FANCA,FIGNL1,GGT2,GMCL1,H2AX,KHDRBS1,KNL1,MCM8,METTL3,MLH1,MLH3,MYBL1,MYCBP,NDC1,NSUN2,PAFAH1B2,PAFAH1B3,POC1A,PTTG1,RAD51C,RPL39L,SEPTIN12,SLIRP,SYCP1,TRIP13,TSGA10 |
| GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 1.9e-05 | 2.9e-04 | 1139 | 51 | 8 | CCAR2,ELL3,GTF2F2,HMGN1,HTATSF1,LEO1,SUPT16H,TSFM |
| GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY | 1.9e-05 | 3.0e-04 | 1139 | 181 | 15 | BRCA1,CARM1,CCNE1,DNAAF4,ESR2,FKBP4,LEF1,NR4A2,PAGR1,PARP1,PHB,PPARGC1B,SAFB,SAFB2,SKP2 |
| GO_AGING | 2.0e-05 | 3.2e-04 | 1139 | 323 | 21 | AKT1,APEX1,ATR,CACYBP,CARM1,CTSC,DNAJA3,FBXO5,H2AX,MBD3,MSH6,OPA1,PNPT1,PRKDC,SIN3A,SMC5,SMC6,TERF2,TERT,TNFRSF1B,TYMS |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 2.1e-05 | 3.2e-04 | 1139 | 1428 | 58 | AKT1,ASPM,ATAD5,BRCA1,C1QBP,CAPRIN2,CARM1,CDC20,CHD7,CMKLR1,DDX56,DLX1,DNMT3B,ECT2,EEF2K,EGR3,EIF4G1,ELL3,EPHA3,FBXO5,GATA2,HDAC2,HMGB1,IL12RB1,IL1RAP,IL7R,KIF20B,LEF1,MACROH2A1,MIEF1,MIXL1,MLH1,MYB,NME1,OPA1,PA2G4,PARP1,PAXIP1,PLXNA1,PPARGC1B,PPP1CC,PRKDC,PRPF19,RASGRP1,RHOH,RPS6KA1,SIN3A,SIX1,TERT,TGFB2,THBS1,TNFRSF1B,VEZF1,VHL,WNT10B,XRCC2,XRCC5,ZNF488 |
| GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 2.1e-05 | 3.2e-04 | 1139 | 67 | 9 | ATR,DSCC1,PTGES3,RFC2,RFC3,RFC4,RFC5,WRAP53,XRCC5 |
| GO_DNA_REPLICATION_CHECKPOINT | 2.2e-05 | 3.3e-04 | 1139 | 16 | 5 | CDC45,DNA2,ORC1,TICRR,TIMELESS |
| GO_KINETOCHORE_ASSEMBLY | 2.2e-05 | 3.3e-04 | 1139 | 16 | 5 | CENPE,CENPF,CENPH,CENPS,CENPX |
| GO_PYRIMIDINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS | 2.2e-05 | 3.3e-04 | 1139 | 16 | 5 | CAD,DHODH,DTYMK,TK1,UMPS |
| GO_RNA_SPLICING_VIA_ENDONUCLEOLYTIC_CLEAVAGE_AND_LIGATION | 2.2e-05 | 3.3e-04 | 1139 | 16 | 5 | CLP1,CPSF4,CSTF2,FAM98B,TSEN54 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 2.3e-05 | 3.5e-04 | 1139 | 831 | 39 | AKT1,APEX1,CCAR2,CTSC,DNAAF4,DND1,EIF4G1,ELAVL1,EXOSC2,EXOSC8,FASTKD1,FASTKD3,FBXO22,HMGB1,HNRNPC,HNRNPR,HSPBP1,MAP3K7,METTL3,PAFAH1B2,PBK,PLK1,PNPT1,PSMD5,PSME3,RAB8A,RIDA,SERBP1,SGTA,SLIRP,SNRNP70,SVIP,SYNCRIP,TNFRSF1B,UBE2G2,UCHL5,UQCC2,USP10,WNT10B |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 2.4e-05 | 3.7e-04 | 1139 | 1208 | 51 | ADCY3,AKT1,APEX1,BLM,BRCA1,BRIP1,CDC5L,CHUK,DCPS,DHFR,DNMT1,DNMT3B,ECT2,EEF2K,EIF4E,EPHA3,FANCC,FXN,GKAP1,GPR173,H2AZ1,HDAC2,HMGB1,HOXA2,IRF3,KLRK1,LRP5L,MYB,NME1,NR4A2,OPA1,PARP1,PPARGC1B,PPAT,PRDX3,PRKAR2A,PRKDC,PTPN2,RAB8A,SELENOT,SHPK,SIN3A,SIX1,TIMELESS,TLR4,TNFRSF1B,TRIM41,TWNK,WNT10B,XRCC5,ZNF236 |
| GO_HISTONE_H3_K9_METHYLATION | 2.5e-05 | 3.8e-04 | 1139 | 39 | 7 | BEND3,BRCA1,DNMT1,DNMT3B,MYB,SUV39H1,SUV39H2 |
| GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 2.5e-05 | 3.8e-04 | 1139 | 353 | 22 | ACOX2,ADIPOR2,ASNSD1,BRCA1,CAD,DHFR,ENOPH1,ERLIN1,FABP5,GART,GGT2,GOT2,HACD3,MCAT,MTHFD2L,NDUFAB1,OSBPL3,PER2,PSPH,PTGES3,SLC1A3,SLC45A3 |
| GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | 2.6e-05 | 4.0e-04 | 1139 | 104 | 11 | DDX3X,GTF2F2,HACD3,LEF1,POLR2B,POLR2D,POLR2F,POLR2K,PPIH,RRP1B,TAF11 |
| GO_GLUCOSE_METABOLIC_PROCESS | 2.9e-05 | 4.4e-04 | 1139 | 210 | 16 | AKT1,COX11,CRTC2,DLAT,FABP5,GOT2,GPD2,KHK,PER2,PFKM,PGM5,PTPN2,SDHAF3,SLC25A13,SLC45A3,WDR5 |
| GO_MITOCHONDRIAL_RNA_PROCESSING | 3.0e-05 | 4.5e-04 | 1139 | 17 | 5 | CDK5RAP1,ELAC2,FASTKD5,PNPT1,TRMT10C |
| GO_MITOTIC_CYTOKINESIS | 3.0e-05 | 4.5e-04 | 1139 | 70 | 9 | ANLN,CIT,ECT2,KIF20A,KIF20B,KIF23,KIF4A,PLK1,STMN1 |
| GO_POSITIVE_REGULATION_OF_CYTOKINESIS | 3.0e-05 | 4.5e-04 | 1139 | 40 | 7 | CENPV,CIT,ECT2,KIF14,KIF20B,KIF23,PKP4 |
| GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION | 3.0e-05 | 4.5e-04 | 1139 | 40 | 7 | ATAD5,FANCB,MLH1,PARP1,PAXIP1,TIMELESS,WRAP53 |
| GO_POSITIVE_REGULATION_OF_HISTONE_H3_K4_METHYLATION | 3.0e-05 | 4.5e-04 | 1139 | 17 | 5 | BRCA1,DNMT1,DNMT3B,MYB,PAXIP1 |
| GO_PROTEIN_LOCALIZATION_TO_KINETOCHORE | 3.0e-05 | 4.5e-04 | 1139 | 17 | 5 | BUB3,HASPIN,KNL1,NDC80,TTK |
| GO_PYRIMIDINE_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS | 3.0e-05 | 4.5e-04 | 1139 | 17 | 5 | CAD,DHODH,DUT,TYMS,UMPS |
| GO_RESOLUTION_OF_MEIOTIC_RECOMBINATION_INTERMEDIATES | 3.0e-05 | 4.5e-04 | 1139 | 17 | 5 | CENPS,CENPX,EME1,MLH1,RMI1 |
| GO_RESPONSE_TO_STEROID_HORMONE | 3.2e-05 | 4.8e-04 | 1139 | 385 | 23 | BRCA1,CAD,CARM1,CCNE1,DNAAF4,DNMT3B,EIF4E,ESR2,FKBP4,HNMT,LEF1,NR4A2,PAGR1,PARP1,PHB,PPARGC1B,SAFB,SAFB2,SKP2,TGFB2,THBS1,TYMS,UBE2L3 |
| GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | 3.4e-05 | 5.0e-04 | 1139 | 28 | 6 | ANAPC4,DLGAP5,FEN1,MACROH2A1,SMC5,SMC6 |
| GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION | 3.4e-05 | 5.0e-04 | 1139 | 28 | 6 | BRCA1,DNMT1,DNMT3B,MACROH2A1,MYB,PAXIP1 |
| GO_RNA_POLYMERASE_II_PREINITIATION_COMPLEX_ASSEMBLY | 3.4e-05 | 5.0e-04 | 1139 | 28 | 6 | CAND1,GTF2A2,HMGB1,TAF11,TAF6L,WNT10B |
Num: 16 (Pathways: 158 DK: 4)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (4) | OBSCN, STK17A, STK17B, TSSK4 |
| Light Kinase (14) | BLVRA, GRK3, GRK4, MAP3K1, MAPK13, MET, MYO3B, NTRK3, PDK3, PIK3CD, PRKCI, SNRK, SYK, TNIK |
| Non-kinase Count | 379 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_REGULATION_OF_TRANSPORT | 0.0e+00 | 0.0e+00 | 397 | 1894 | 56 | ABCB4,ADRA2C,AKAP12,ARFGAP1,ARFIP1,BDKRB1,CACNA1A,CACNB4,CRLF2,CX3CL1,DTNBP1,EHD4,GAB2,HDAC3,HIP1R,ICA1,IL10,ITGB3,KCNA7,KCNF1,KCNMB4,LIPG,LPAR3,MPV17L,NDFIP2,NLGN1,NOD2,NR4A3,P2RX4,PDGFB,PLCG2,PLTP,PRKCI,RAB10,RALA,RHBDF2,RIMS1,RRAD,SDC4,SERPINE1,SERPINE2,SH3GL3,SHANK2,SIRT6,SLC25A4,SLC8B1,STON1,SYK,SYT17,SYT7,TACR2,TBC1D20,TBC1D4,TMSB4X,TSPAN13,UNC13A |
| GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 1825 | 52 | ADRA2C,AKAP12,AMOTL1,ANGPTL4,AP3D1,BCL6,CRLF2,CX3CL1,EBI3,EPAS1,FLRT2,FOS,FOXP2,FST,GLIPR2,HDAC3,IL10,IL6ST,IRF5,IRF7,ITGB3,L1CAM,LBP,LIPG,LPAR3,MAPK13,MET,NCMAP,NLGN1,NOD2,NR4A3,NTRK3,P2RX4,PDGFB,PLCG2,PRKCI,RIMS1,RNF112,SASH1,SERPINE1,SERPINE2,SH3GL3,SHANK2,SIRT6,SYK,SYT17,TACR2,TBX5,TMSB4X,TNFSF9,UNC13A,UTP25 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 0.0e+00 | 397 | 1869 | 52 | ADRA2C,AKAP12,BMP3,CASP4,CCL22,CRLF2,CX3CL1,DAAM2,DTNBP1,FZD7,GLIPR2,HCST,HDAC3,HIP1R,IL10,IL6ST,IRF7,ITGB3,KCTD13,LBP,LPAR3,MAML3,MAP3K1,MET,MGAT5,NDFIP2,NLGN1,NOD2,NTRK3,P2RX4,PDGFB,PIK3CD,PRKCI,RIMS1,SASH1,SERPINE2,SH2B2,SHANK2,SLC24A2,SOCS3,SPRED3,SYK,SYT7,TAB3,TACR2,TCIM,TGM2,TMEM198,TNIK,TRIM25,UNC13A,UNC5CL |
| GO_SECRETION | 0.0e+00 | 0.0e+00 | 397 | 1680 | 48 | ABCB4,ADRA2C,AKAP12,ARFIP1,BST1,CACNA1A,CD55,CRLF2,CX3CL1,DSC1,DTNBP1,FGL2,GAB2,HEXB,HIP1R,HNF1A,ICA1,IL10,ITGB3,KCNMB4,LCP2,LTA4H,NLGN1,NOD2,NR4A3,P2RX4,PDGFB,PIK3CD,PRKCI,RAB10,RALA,RHBDF2,RIMS1,SDC4,SERPINE1,SERPINE2,SLC25A4,SLC8B1,SLCO4C1,SYK,SYT17,SYT7,TACR2,TIMP1,TMSB4X,TNFAIP6,TSPOAP1,UNC13A |
| GO_LOCOMOTION | 0.0e+00 | 0.0e+00 | 397 | 1984 | 51 | AFDN,AKAP12,AMOTL1,BDKRB1,BST1,CCL22,CEACAM5,CHMP2B,CHMP4C,CNTN4,CX3CL1,DOCK4,FLRT2,GAB2,GLIPR2,GNA12,HEXB,IL10,ITGB3,KCTD13,L1CAM,LBP,MET,MGAT5,MISP,NR4A3,NTRK3,P2RX4,PDGFB,PIK3CD,PLCG2,PLTP,PRKCI,RALA,SASH1,SDC4,SERPINE1,SERPINE2,SLC8B1,SYK,TACR2,TBX5,TEKT3,TIMP1,TMSB4X,TNFAIP6,TRIM25,TTC21A,VASP,VPS37B,ZSWIM6 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 0.0e+00 | 397 | 1665 | 45 | ADRA2C,AFDN,AKAP12,AMOTL1,BMP3,CACNA1A,CACNB4,CCL22,CNTN4,CX3CL1,DAAM2,DTNBP1,FZD7,GJB2,HNF1A,ICA1,KCNMB4,KCTD13,LPAR3,MPZ,MYCBPAP,NLGN1,NLGN4X,NPTX2,P2RX4,PCDH1,PDGFB,PHEX,PLCG2,RIMS1,SERPINE2,SHANK2,SLC24A2,SLC25A4,SLC8B1,SYT7,TACR2,TBX5,TLE1,TMEM198,TNFAIP6,TNFSF9,TNIK,TSPOAP1,UNC13A |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 0.0e+00 | 397 | 1781 | 46 | ACAP1,ADRA2C,AFDN,ARFGAP1,ARHGAP12,ARHGAP22,ARHGAP32,CASP4,CCL22,CX3CL1,DCP1B,DENND1A,DOCK4,DOCK9,ERRFI1,GPRC5A,HIP1R,IL10,ITGB3,LCP2,LPAR3,MAP3K1,MET,MID1IP1,MMP17,MRNIP,NOD2,NTRK3,PDGFB,PDP1,PLCG2,PRKCI,RGS11,RGS20,RIC1,SASH1,SDC4,SYK,TAB3,TBC1D20,TBC1D4,TCIM,TMSB4X,TNIK,TRIM25,TSSK4 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 0.0e+00 | 397 | 1748 | 45 | AKAP12,ALDH1A2,ANGPTL4,BCL2A1,BCL6,BMP3,CASP4,CEACAM5,CHST11,CX3CL1,EYA2,FOS,HDAC3,HIP1R,IL10,IL6ST,IRF5,IRF7,MET,MMP3,MPV17L,NAIP,NGEF,NOD2,NPC1,NR4A3,NTRK3,OBSCN,PACRG,PELI3,PIK3CD,PLCG2,PRKCI,RASSF6,SERPINE1,SLC25A4,SOCS3,STK17A,STK17B,SYK,TCIM,TGM2,TIMP1,TLE1,TNFSF9 |
| GO_BIOLOGICAL_ADHESION | 0.0e+00 | 0.0e+00 | 397 | 1425 | 40 | AFDN,AP3D1,BCAM,BCL6,BST1,CD55,CEACAM5,CLEC4M,CNTN4,CX3CL1,DSC1,EBI3,EDIL3,EGFL7,FGL2,FLRT2,FZD7,IL10,IL6ST,ITGB3,L1CAM,LRRC1,MAGI1,MPZ,NLGN1,NLGN4X,NOD2,NR4A3,PCDH1,PDLIM5,RAB10,SDC4,SERPINE1,SERPINE2,SYK,TGM2,TINAGL1,TNFAIP6,TNFSF9,TTYH1 |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 0.0e+00 | 0.0e+00 | 397 | 1429 | 40 | ACAP1,ADRA2C,AFDN,ARFGAP1,ARHGAP12,ARHGAP22,ARHGAP32,CASP4,CCL22,CX3CL1,DCP1B,DENND1A,DOCK4,DOCK9,ERRFI1,GPRC5A,HIP1R,ITGB3,LCP2,LPAR3,MAP3K1,MID1IP1,MMP17,MRNIP,NOD2,NTRK3,PDGFB,PDP1,RGS11,RGS20,RIC1,SASH1,SDC4,SYK,TAB3,TBC1D20,TBC1D4,TCIM,TMSB4X,TNIK |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 397 | 1994 | 48 | ADRA2C,AKAP12,BDKRB1,BMP3,BST1,CBLB,CCL22,CCNA1,CX3CL1,DTNBP1,EHD4,ERRFI1,FZD7,GLIPR2,GPRC5A,GRK3,GRK4,HCST,HDAC3,IL6ST,ITGB3,LCP2,LPAR3,MAP3K1,MAPK13,MET,MRNIP,MYO3B,NOD2,NTRK3,OBSCN,PDGFB,PDK3,PIK3CD,PRKCI,SASH1,SDC4,SNRK,SOCS3,SPRED3,STK17A,STK17B,SYK,TAB3,TCIM,TNIK,TSSK4,UNC5CL |
| GO_CELL_CELL_ADHESION | 0.0e+00 | 0.0e+00 | 397 | 847 | 30 | AFDN,AP3D1,BCL6,CD55,CEACAM5,CLEC4M,CNTN4,CX3CL1,DSC1,EBI3,FGL2,IL10,IL6ST,ITGB3,L1CAM,LRRC1,MAGI1,MPZ,NLGN1,NLGN4X,NOD2,NR4A3,PCDH1,PDLIM5,RAB10,SDC4,SERPINE2,SYK,TNFSF9,TTYH1 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 0.0e+00 | 397 | 1863 | 46 | ADRA2C,AKAP12,ARFGAP1,ARFGEF3,ARHGAP12,ARHGAP22,ARHGAP32,BCL6,BMP3,BST1,CCL22,CX3CL1,DENND1A,DTNBP1,ERRFI1,FGD6,FZD7,GLIPR2,GNA12,HCST,HDAC3,KCTD13,LPAR3,MAP3K1,MET,NDFIP2,NGEF,NLGN1,NOD2,NTRK3,OBSCN,P2RX4,PDGFB,PIK3CD,SASH1,SERPINE2,SPRED3,SYK,TAB3,TCIM,TGM2,TLE1,TMSB4X,TNIK,TRIM25,UNC5CL |
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 397 | 1335 | 38 | ADD3,AFAP1,AMOTL1,ARFGEF3,ARHGAP12,BCL6,BST1,CFAP73,CHMP2B,CHMP4C,CX3CL1,DAAM2,DTNBP1,FGD6,HDAC3,HIP1R,KCTD13,KRT15,MET,MID1IP1,MISP,NLGN1,NTRK3,OBSCN,PDLIM5,PRKCI,RALA,SDC4,SPATA4,SPIRE1,TMSB4X,TNIK,TNNT1,TPPP,TUBAL3,TUBB8,VASP,XIRP1 |
| GO_NEUROGENESIS | 0.0e+00 | 0.0e+00 | 397 | 1625 | 42 | ADRA2C,AGTPBP1,ALDH1A2,ATCAY,BCL6,CNTN4,CX3CL1,DAAM2,DTNBP1,FLRT2,FZD7,GAB2,HEXB,HEY1,IL6ST,L1CAM,LDLR,LPAR3,MET,MOSMO,NCMAP,NGEF,NLGN1,NLGN4X,NR4A3,NTRK3,P2RX4,PDLIM5,PIK3CD,PRKCI,RAB10,RIMS1,RNF112,SDC4,SERPINE2,SH3GL3,SHANK2,SYT17,TNIK,UNC13A,VASP,ZSWIM6 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 397 | 1698 | 43 | ABCB4,AKAP12,AKR1A1,ALDH1A2,ATP6V1B2,BDKRB1,CACNA1A,CASP4,CD55,CX3CL1,DTNBP1,ERRFI1,FOS,FOXP2,FZD7,GJB2,IL10,IRF5,LBP,LDLR,MAPK13,MET,MMP3,NOD2,NR4A3,NTRK3,P2RX4,PDGFB,PDK3,PHEX,PLCG2,PRKCI,PTGES,PTPRE,RAB10,RNF112,SASH1,SERPINE1,SH2B2,SOCS3,TBC1D4,TIMP1,TRIM25 |
| GO_CELL_ACTIVATION | 0.0e+00 | 0.0e+00 | 397 | 1442 | 39 | ADRA2C,AKAP12,AP3D1,BCL6,BST1,CD55,CRLF2,CX3CL1,DSC1,EBI3,FGL2,FZD7,GAB2,GNA12,HEXB,HNF1A,IL10,IL6ST,ITGB3,LBP,LCP2,LDLR,LTA4H,NOD2,NR4A3,P2RX4,PDGFB,PIK3CD,PLCG2,RAB10,SDC4,SERPINE2,SLCO4C1,SYK,TCIM,TIMP1,TNFAIP6,TNFSF9,TREML2 |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 0.0e+00 | 0.0e+00 | 397 | 1881 | 45 | ADRA2C,AP3D1,BCL6,CEACAM5,CNTN4,CX3CL1,DAAM2,ERRFI1,FGL2,FLRT2,FOS,FST,FZD7,GLIPR2,HEY1,IL6ST,IRF7,ITGB3,L1CAM,LDLR,LPAR3,MAMSTR,MOSMO,NGEF,NLGN1,NR4A3,NTRK3,P2RX4,PDGFB,PDLIM5,PRKCI,RIMS1,RNF112,SERPINE1,SERPINE2,SH3GL3,SHANK2,SOCS3,SYK,SYT17,TBX5,TNFSF9,TNIK,UNC13A,ZSWIM6 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 397 | 1208 | 35 | ABCB4,AKR1A1,ALDH1A2,ATP6V1B2,CACNA1A,CASP4,CD55,CX3CL1,DTNBP1,ERRFI1,FOS,FZD7,GJB2,IL10,LBP,LDLR,MAPK13,MET,MMP3,NOD2,NR4A3,NTRK3,P2RX4,PDGFB,PDK3,PHEX,PRKCI,PTPRE,RAB10,RNF112,SASH1,SERPINE1,SH2B2,SOCS3,TBC1D4 |
| GO_CELL_MOTILITY | 0.0e+00 | 0.0e+00 | 397 | 1758 | 43 | AFDN,AKAP12,AMOTL1,BDKRB1,BST1,CCL22,CEACAM5,CX3CL1,DOCK4,FLRT2,GLIPR2,GNA12,HEXB,IL10,ITGB3,KCTD13,L1CAM,LBP,MET,MGAT5,MISP,NR4A3,NTRK3,P2RX4,PDGFB,PIK3CD,PLCG2,PLTP,PRKCI,SASH1,SDC4,SERPINE1,SERPINE2,SLC8B1,SYK,TACR2,TBX5,TEKT3,TIMP1,TMSB4X,TNFAIP6,TTC21A,ZSWIM6 |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 0.0e+00 | 0.0e+00 | 397 | 1559 | 40 | BCL6,BST1,CASP4,CX3CL1,DTNBP1,ERRFI1,EYA2,FGL2,FZD7,HDAC3,IL10,IL6ST,IRF7,LBP,LDLR,MAP3K1,MAPK13,MET,MMP3,MRNIP,NOD2,NR4A3,NTRK3,PDGFB,PLCG2,SASH1,SERPINE1,SERPINE2,SIRT6,SOCS3,SPIRE1,SPRED3,SYK,TAB3,TGM2,TMSB4X,TNFAIP6,TNIK,TREML2,UNC5CL |
| GO_POSITIVE_REGULATION_OF_LOCOMOTION | 0.0e+00 | 1.0e-07 | 397 | 604 | 24 | AKAP12,AMOTL1,BDKRB1,CHMP2B,CHMP4C,CX3CL1,DOCK4,GLIPR2,ITGB3,LBP,MET,MGAT5,NR4A3,NTRK3,P2RX4,PDGFB,PIK3CD,PLCG2,SASH1,SERPINE1,TACR2,TMSB4X,TNFAIP6,VPS37B |
| GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 1.0e-07 | 397 | 1124 | 33 | BCL6,BST1,CASP4,CD55,CX3CL1,FGL2,GRK4,IL10,IL6ST,IRF7,LBP,LDLR,MAP3K1,MAPK13,MET,MMP3,NOD2,NTRK3,P2RX4,PDGFB,PLCG2,SASH1,SERPINE1,SERPINE2,SLC8B1,SOCS3,SYK,TAB3,TGM2,TMSB4X,TNFAIP6,TREML2,ZSWIM6 |
| GO_REGULATION_OF_SECRETION | 0.0e+00 | 1.0e-07 | 397 | 824 | 28 | ADRA2C,AKAP12,ARFIP1,CACNA1A,CRLF2,CX3CL1,DTNBP1,GAB2,HIP1R,ICA1,IL10,KCNMB4,NLGN1,NOD2,P2RX4,RAB10,RALA,RHBDF2,RIMS1,SDC4,SLC25A4,SLC8B1,SYK,SYT17,SYT7,TACR2,TMSB4X,UNC13A |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 397 | 1823 | 43 | ADRA2C,AKAP12,ARFGEF3,BDKRB1,BMP3,BST1,CBLB,CCL22,CCNA1,CX3CL1,DTNBP1,EHD4,ERRFI1,FZD7,GLIPR2,GPRC5A,HDAC3,IL6ST,ITGB3,KCTD20,LCP2,LDLR,LPAR3,MAP3K1,MGAT5,MRNIP,NOD2,NTRK3,PDGFB,PDK3,PDP1,SASH1,SDC4,SIRT6,SOCS3,SPRED3,SYK,TAB3,TCIM,TMEM225B,TMSB4X,TNIK,UNC5CL |
| GO_RESPONSE_TO_CYTOKINE | 0.0e+00 | 1.0e-07 | 397 | 1210 | 34 | AKAP12,ALDH1A2,BCL6,CASP4,CCL22,CRLF2,CX3CL1,EBI3,FOS,GAB2,IL10,IL6ST,IRF5,IRF7,ISG20,LBP,MAPK13,MMP3,MT1X,NFIL3,NOD2,PDGFB,PELI3,PIK3CD,PRKCI,PTGES,RALA,SOCS3,SYK,TAB3,TIMP1,TMSB4X,TNFSF9,TRIM25 |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 0.0e+00 | 1.0e-07 | 397 | 791 | 27 | BCL6,CASP4,CCL22,CRLF2,CX3CL1,EBI3,FOS,GAB2,IL10,IL6ST,IRF5,IRF7,ISG20,LBP,MMP3,NOD2,PDGFB,PELI3,PIK3CD,RALA,SOCS3,SYK,TAB3,TIMP1,TMSB4X,TNFSF9,TRIM25 |
| GO_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 1.0e-07 | 397 | 477 | 21 | ACAP1,AFDN,ARFGAP1,ARHGAP12,ARHGAP22,ARHGAP32,BCL6,CCL22,CX3CL1,DENND1A,DOCK4,DOCK9,ERRFI1,FGD6,NGEF,NTRK3,RGS11,RGS20,RIC1,TBC1D20,TBC1D4 |
| GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 0.0e+00 | 1.0e-07 | 397 | 1107 | 32 | AFDN,AKAP12,AMOTL1,BCL6,BDKRB1,BST1,CX3CL1,DOCK4,FLRT2,GLIPR2,GNA12,ITGB3,LBP,MET,MGAT5,NR4A3,NTRK3,P2RX4,PDGFB,PIK3CD,PLCG2,SASH1,SDC4,SERPINE1,SERPINE2,SLC8B1,TACR2,TBX5,TIMP1,TMSB4X,TNFAIP6,ZSWIM6 |
| GO_TAXIS | 0.0e+00 | 2.0e-07 | 397 | 652 | 24 | BST1,CCL22,CNTN4,CX3CL1,DOCK4,FLRT2,GAB2,IL10,ITGB3,L1CAM,LBP,MET,NR4A3,NTRK3,P2RX4,PDGFB,PIK3CD,RALA,SERPINE1,SLC8B1,SYK,TMSB4X,VASP,ZSWIM6 |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 0.0e+00 | 3.0e-07 | 397 | 1287 | 34 | ACAP1,AFDN,ANGPTL4,ARFGAP1,ARFGEF3,ARHGAP12,ARHGAP22,ARHGAP32,BCL6,CASP4,CCL22,CFAP73,CX3CL1,DENND1A,DOCK4,DOCK9,ERRFI1,FGD6,HIP1R,MGAT5,NAIP,NGEF,NTRK3,PI3,RGS11,RGS20,RIC1,SERPINE1,SERPINE2,SYK,TBC1D20,TBC1D4,TIMP1,TMEM225B |
| GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 0.0e+00 | 4.0e-07 | 397 | 1428 | 36 | ADRA2C,ANGPTL4,AP3D1,BCL6,CX3CL1,FLRT2,FOS,FOXP2,FST,GLIPR2,IL10,IL6ST,L1CAM,LPAR3,MAMSTR,NCMAP,NLGN1,NTRK3,P2RX4,PDGFB,PRKCI,RIMS1,RNF112,SASH1,SERPINE1,SERPINE2,SH3GL3,SHANK2,SIRT6,SOCS3,SYK,SYT17,TBX5,TNFSF9,UNC13A,UTP25 |
| GO_NEURON_DIFFERENTIATION | 0.0e+00 | 4.0e-07 | 397 | 1365 | 35 | ADRA2C,AGTPBP1,ALDH1A2,ATCAY,BCL6,CNTN4,CX3CL1,DTNBP1,FLRT2,FZD7,GAB2,HEY1,L1CAM,LPAR3,MET,MOSMO,NGEF,NLGN1,NLGN4X,NR4A3,NTRK3,PDLIM5,PIK3CD,PRKCI,RAB10,RIMS1,RNF112,SDC4,SH3GL3,SHANK2,SYT17,TNIK,UNC13A,VASP,ZSWIM6 |
| GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 0.0e+00 | 6.0e-07 | 397 | 928 | 28 | ADRA2C,BCL6,CNTN4,CX3CL1,DAAM2,FLRT2,HEY1,IL6ST,L1CAM,LDLR,LPAR3,MOSMO,NCMAP,NGEF,NLGN1,NTRK3,P2RX4,PDLIM5,PRKCI,RIMS1,RNF112,SERPINE2,SH3GL3,SHANK2,SYT17,TNIK,UNC13A,ZSWIM6 |
| GO_TUBE_DEVELOPMENT | 0.0e+00 | 6.0e-07 | 397 | 1122 | 31 | ALDH1A2,AMOTL1,ANGPTL4,ARHGAP22,CX3CL1,DHCR7,EGFL7,EPAS1,ERRFI1,FOXP2,GJB2,GZF1,HEY1,IL10,ITGB3,LDLR,MET,NR4A3,PHEX,RALA,SASH1,SAT1,SDC4,SERPINE1,SERPINE2,SIRT6,SYK,TBC1D20,TBX5,TGM2,VASP |
| GO_REGULATION_OF_ION_TRANSPORT | 0.0e+00 | 6.0e-07 | 397 | 699 | 24 | ABCB4,BDKRB1,CACNA1A,CACNB4,CX3CL1,DTNBP1,ITGB3,KCNA7,KCNF1,LPAR3,NLGN1,P2RX4,PDGFB,PLCG2,RRAD,SERPINE2,SHANK2,SLC8B1,SYK,SYT17,SYT7,TACR2,TMSB4X,TSPAN13 |
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 7.0e-07 | 397 | 1405 | 35 | ABCB4,ALDH1A2,ANGPTL4,CBR1,CYP27C1,DHCR7,ELOVL7,FAAH,HDAC3,HEXB,HSD17B7,LARGE1,LDLR,LIPG,LTA4H,MID1IP1,MTMR14,MVD,NOD2,NPC1,NR4A3,PDGFB,PDK3,PDP1,PIGH,PIK3CD,PLCG2,PLTP,PTGES,SDC4,SDR16C5,SDR42E1,SOCS3,SQLE,TSPOAP1 |
| GO_ION_TRANSPORT | 0.0e+00 | 8.0e-07 | 397 | 1692 | 39 | ABCB4,ANKH,ANO7,ATP6V1B2,BDKRB1,CACNA1A,CACNB4,CX3CL1,DTNBP1,ITGB3,KCNA7,KCNF1,KCNMB4,LDLR,LPAR3,MID1IP1,NDFIP2,NLGN1,P2RX4,PDGFB,PLCG2,PLTP,RIMS1,RRAD,SERPINE2,SHANK2,SLC24A2,SLC25A4,SLC8B1,SLC9A2,SLCO4C1,SYK,SYT17,SYT7,TACR2,TMSB4X,TSPAN13,TSPOAP1,TTYH1 |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 8.0e-07 | 397 | 766 | 25 | ADD3,AMOTL1,ARFGEF3,ARHGAP12,BCL6,BST1,CX3CL1,DAAM2,DTNBP1,FGD6,HIP1R,KCTD13,MET,NTRK3,OBSCN,PDLIM5,PRKCI,RALA,SDC4,SPIRE1,TMSB4X,TNIK,TNNT1,VASP,XIRP1 |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 8.0e-07 | 397 | 1141 | 31 | BCL6,CNTN4,DTNBP1,FGD6,FLRT2,FZD7,GAB2,GNA12,HEXB,ITGB3,L1CAM,LPAR3,MET,NCMAP,NGEF,NLGN1,NR4A3,NTRK3,OBSCN,PDLIM5,PIK3CD,RAB10,RIMS1,SHANK2,SYT17,TBC1D20,TNIK,TNNT1,UNC13A,VASP,ZSWIM6 |
| GO_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY | 0.0e+00 | 1.0e-06 | 397 | 402 | 18 | ACAP1,AFDN,ARFGAP1,ARHGAP12,ARHGAP22,ARHGAP32,CCL22,CX3CL1,DENND1A,DOCK4,DOCK9,ERRFI1,NTRK3,RGS11,RGS20,RIC1,TBC1D20,TBC1D4 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 0.0e+00 | 1.1e-06 | 397 | 1030 | 29 | ANGPTL4,BCL2A1,BCL6,CEACAM5,CHST11,CX3CL1,EYA2,HDAC3,HIP1R,IL10,IL6ST,IRF7,MET,MPV17L,NAIP,NOD2,NPC1,NR4A3,NTRK3,PACRG,PELI3,PLCG2,PRKCI,SERPINE1,SLC25A4,SOCS3,TCIM,TIMP1,TLE1 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 1.4e-06 | 397 | 1741 | 39 | AKAP12,AP3D1,ARFGAP1,ARFIP1,BCAP29,CBLB,CD55,CHMP2B,CHMP4C,DENND1A,DTNBP1,EHD4,GAB2,GOLGA7B,HDAC3,LDLR,LRRC1,MID1IP1,NLGN1,NPC1,NR4A3,PIK3CD,PRKCI,RAB10,RAB39B,RIC1,RIMS1,SPIRE1,SYK,SYT7,TBC1D20,TBC1D4,TINAGL1,TRAPPC3L,TSNARE1,TTC21A,VPS37B,WASHC4,ZDHHC11 |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 1.5e-06 | 397 | 984 | 28 | ABCB4,AKAP12,BDKRB1,CRLF2,CX3CL1,DTNBP1,GAB2,HDAC3,HIP1R,IL10,LIPG,LPAR3,NLGN1,NOD2,NR4A3,P2RX4,PDGFB,PLCG2,PLTP,PRKCI,SDC4,SERPINE1,SYK,SYT7,TACR2,TBC1D20,TMSB4X,UNC13A |
| GO_INFLAMMATORY_RESPONSE | 0.0e+00 | 2.8e-06 | 397 | 765 | 24 | BCL6,BDKRB1,BST1,CASP4,CCL22,CX3CL1,FOS,IL10,IL6ST,LBP,LDLR,MAPK13,MMP3,NAIP,NOD2,PIK3CD,PTGES,SERPINE1,SOCS3,SYK,TGM2,TIMP1,TMSB4X,TNFAIP6 |
| GO_REGULATION_OF_CELL_DEVELOPMENT | 0.0e+00 | 3.0e-06 | 397 | 955 | 27 | ADRA2C,BCL6,CNTN4,CX3CL1,DAAM2,FLRT2,HEY1,IL6ST,L1CAM,LDLR,LPAR3,MOSMO,NGEF,NLGN1,NTRK3,P2RX4,PDLIM5,PRKCI,RIMS1,RNF112,SERPINE2,SH3GL3,SHANK2,SYT17,TNIK,UNC13A,ZSWIM6 |
| GO_EXOCYTOSIS | 0.0e+00 | 3.6e-06 | 397 | 900 | 26 | BST1,CD55,DSC1,DTNBP1,FGL2,GAB2,HEXB,ITGB3,LTA4H,NLGN1,NR4A3,PDGFB,PIK3CD,RAB10,RALA,RIMS1,SDC4,SERPINE1,SLCO4C1,SYK,SYT17,SYT7,TIMP1,TMSB4X,TNFAIP6,UNC13A |
| GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 0.0e+00 | 3.6e-06 | 397 | 547 | 20 | ARFGAP1,DTNBP1,EHD4,GAB2,HIP1R,ITGB3,NLGN1,PLCG2,RAB10,RALA,RIMS1,SDC4,SERPINE1,SH3GL3,STON1,SYK,SYT17,SYT7,TBC1D20,TBC1D4 |
| GO_ENDOCYTOSIS | 0.0e+00 | 3.7e-06 | 397 | 661 | 22 | ARFGAP1,ARHGAP12,CLEC4M,DENND1A,EHD4,GRK3,GRK4,HIP1R,ITGB3,LDLR,MASP1,NEURL3,NLGN1,NLGN4X,NPC1,PLCG2,SERPINE1,SH3GL3,STON1,SYK,SYT7,TINAGL1 |
| GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 0.0e+00 | 4.0e-06 | 397 | 1670 | 37 | AP3D1,BCL6,BDKRB1,BST1,CD55,CLEC2D,CRLF2,CX3CL1,EBI3,FCRLB,FGL2,FOS,GAB2,HCST,IL10,IL6ST,IRF7,LBP,LCP2,LDLR,MAP3K1,MASP1,NOD2,NR4A3,P2RX4,PIK3CD,PLCG2,SDC4,SERPINE1,SH2B2,SLC8B1,SOCS3,SYK,TAB3,TCIM,TNFSF9,TREML2 |
| GO_REPRODUCTION | 0.0e+00 | 4.4e-06 | 397 | 1457 | 34 | ADRA2C,BCL6,CCNA1,EPAS1,FAM50A,FOS,FST,GJB2,GNRH2,GTSF1,HEXB,HEY1,IL10,KDM1B,MYCBPAP,OSBP2,PACRG,PDGFB,PI3,PLTP,RIMS1,SERPINE2,SLCO4C1,SOCS3,SPIRE1,TACR2,TBC1D20,TEKT3,TEX19,TIMP1,TNFAIP6,TSSK4,TTC21A,TUBB8 |
| GO_SYNAPTIC_SIGNALING | 0.0e+00 | 4.9e-06 | 397 | 733 | 23 | AKAP12,CACNA1A,CACNB4,CNTN4,CX3CL1,DTNBP1,KCNMB4,KCTD13,LPAR3,MPZ,MYCBPAP,NLGN1,NLGN4X,NPTX2,P2RX4,RIMS1,SERPINE2,SHANK2,SLC24A2,SYT7,TACR2,TSPOAP1,UNC13A |
| GO_REGULATION_OF_PHOSPHORYLATION | 0.0e+00 | 5.9e-06 | 397 | 1625 | 36 | ADRA2C,AKAP12,BDKRB1,BMP3,BST1,CBLB,CCL22,CCNA1,CX3CL1,DTNBP1,EHD4,ERRFI1,FZD7,GLIPR2,GPRC5A,HDAC3,IL6ST,ITGB3,KCTD20,LCP2,LPAR3,MAP3K1,MRNIP,NOD2,NTRK3,PDGFB,SASH1,SDC4,SIRT6,SOCS3,SPRED3,SYK,TAB3,TCIM,TNIK,UNC5CL |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 0.0e+00 | 6.0e-06 | 397 | 569 | 20 | ARFGAP1,ARFGEF3,ARHGAP12,ARHGAP22,ARHGAP32,BCL6,DENND1A,DOCK4,DOCK6,DOCK9,FGD6,GNA12,KCTD13,MET,NGEF,OBSCN,RAB10,RAB39B,RALA,RRAD |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0.0e+00 | 6.0e-06 | 397 | 1703 | 37 | ARHGAP12,BCL6,CBLB,CD55,CHST11,CX3CL1,EGFL7,ERRFI1,EYA2,FCRLB,FGL2,FST,GPRC5A,GRK4,HDAC3,HEY1,IL10,KCTD13,LDLR,MET,MOSMO,MPV17L,NLGN4X,NR4A3,PDGFB,PELI3,PTPRE,RGS11,RGS20,SERPINE1,SERPINE2,SOCS3,SPRED3,TCIM,TLE1,TMSB4X,TNFAIP6 |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 6.2e-06 | 397 | 687 | 22 | ADRA2C,CX3CL1,DOCK6,DOCK9,DTNBP1,FZD7,GNA12,IL10,ITGB3,LARGE1,LCP2,NTRK3,P2RX4,PDGFB,PLCG2,SDC4,SERPINE1,SERPINE2,SH2B2,SYK,SYT7,TIMP1 |
| GO_WOUND_HEALING | 0.0e+00 | 6.2e-06 | 397 | 572 | 20 | ADRA2C,CX3CL1,DOCK6,DOCK9,DTNBP1,FZD7,GNA12,ITGB3,LARGE1,LCP2,P2RX4,PDGFB,PLCG2,SDC4,SERPINE1,SERPINE2,SH2B2,SYK,SYT7,TIMP1 |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 1.0e-07 | 7.6e-06 | 397 | 1427 | 33 | ARHGAP12,BCL6,CBLB,CHST11,CX3CL1,EGFL7,ERRFI1,EYA2,FST,GPRC5A,GRK4,HDAC3,HEY1,IL10,KCTD13,MET,MOSMO,MPV17L,NLGN4X,PELI3,PTPRE,RGS11,RGS20,SERPINE1,SERPINE2,SHANK2,SLC24A2,SOCS3,SPRED3,TACR2,TCIM,TLE1,TMSB4X |
| GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1.0e-07 | 7.6e-06 | 397 | 1146 | 29 | ADRA2C,AKAP12,BMP3,CCL22,CX3CL1,EHD4,FZD7,GLIPR2,GPRC5A,HDAC3,IL6ST,ITGB3,KCTD20,LCP2,LPAR3,MAP3K1,MRNIP,NOD2,NTRK3,PDGFB,SASH1,SDC4,SOCS3,SYK,TAB3,TCIM,TMSB4X,TNIK,UNC5CL |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 1.0e-07 | 8.3e-06 | 397 | 1962 | 40 | AKR1A1,ALDH1A2,ATCAY,B3GNT7,CBR1,CHST11,CHST15,CSGALNACT2,CYP27C1,DHCR7,ELOVL7,FAAH,FGGY,FOXK1,FUT4,GMDS,GSTO2,HEXB,HSD17B7,LDLR,LTA4H,MID1IP1,MVD,NME7,NPC1,NR4A3,NUDT10,PDGFB,PDK3,PDP1,PLCG2,PLTP,PRUNE2,PTGES,SDR16C5,SIRT6,SLC19A3,SQLE,SYK,TMSB4X |
| GO_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 1.0e-07 | 9.6e-06 | 397 | 960 | 26 | ALDH1A2,BCL6,BST1,CD55,CRLF2,CX3CL1,EBI3,EGFL7,FOXP2,FZD7,GAB2,IL10,IL6ST,ITGB3,MVD,NOD2,NR4A3,NTRK3,PDGFB,PRKCI,SIRT6,SYK,TBX5,TGM2,TIMP1,TNFSF9 |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1.0e-07 | 9.6e-06 | 397 | 1026 | 27 | ADRA2C,AKAP12,CCL22,CX3CL1,FZD7,GLIPR2,HCST,HDAC3,LPAR3,MAP3K1,MET,NDFIP2,NLGN1,NOD2,NTRK3,P2RX4,PDGFB,PIK3CD,SASH1,SPRED3,SYK,TAB3,TCIM,TGM2,TNIK,TRIM25,UNC5CL |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 1.0e-07 | 1.2e-05 | 397 | 1177 | 29 | AGTPBP1,ALDH1A2,AMOTL1,ANGPTL4,ARHGAP22,BCL6,CX3CL1,EGFL7,EPAS1,EYA2,FZD7,HEY1,IL10,ITGB3,NCMAP,NR4A3,OBSCN,RALA,SASH1,SAT1,SDC4,SERPINE1,SIRT6,SYK,TBC1D20,TBX5,TGM2,TNNT1,VASP |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1.0e-07 | 1.2e-05 | 397 | 1247 | 30 | ADRA2C,AKAP12,BCL6,BMP3,CCL22,CX3CL1,EHD4,FZD7,GLIPR2,GPRC5A,HDAC3,IL6ST,ITGB3,LCP2,LPAR3,MAP3K1,MRNIP,NDFIP2,NOD2,NTRK3,PDGFB,SASH1,SDC4,SDR16C5,SOCS3,SYK,TAB3,TCIM,TNIK,UNC5CL |
| GO_REGULATION_OF_NEURON_DIFFERENTIATION | 1.0e-07 | 1.2e-05 | 397 | 659 | 21 | ADRA2C,BCL6,CNTN4,CX3CL1,HEY1,L1CAM,LPAR3,MOSMO,NGEF,NLGN1,NTRK3,PDLIM5,PRKCI,RIMS1,RNF112,SH3GL3,SHANK2,SYT17,TNIK,UNC13A,ZSWIM6 |
| GO_CATION_TRANSPORT | 1.0e-07 | 1.2e-05 | 397 | 1180 | 29 | ATP6V1B2,BDKRB1,CACNA1A,CACNB4,CX3CL1,DTNBP1,ITGB3,KCNA7,KCNF1,KCNMB4,LPAR3,NDFIP2,NLGN1,P2RX4,PDGFB,PLCG2,RRAD,SERPINE2,SHANK2,SLC24A2,SLC8B1,SLC9A2,SYK,SYT17,SYT7,TACR2,TMSB4X,TSPAN13,TTYH1 |
| GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 1.0e-07 | 1.3e-05 | 397 | 547 | 19 | ADRA2C,BCL6,CX3CL1,FLRT2,IL6ST,L1CAM,LPAR3,NCMAP,NLGN1,NTRK3,P2RX4,PRKCI,RIMS1,RNF112,SERPINE2,SH3GL3,SHANK2,SYT17,UNC13A |
| GO_REGULATION_OF_INFLAMMATORY_RESPONSE | 1.0e-07 | 1.3e-05 | 397 | 387 | 16 | BCL6,BST1,CASP4,CX3CL1,IL10,IL6ST,LBP,LDLR,MAPK13,MMP3,NOD2,SERPINE1,SOCS3,TGM2,TMSB4X,TNFAIP6 |
| GO_HOMEOSTATIC_PROCESS | 1.0e-07 | 1.4e-05 | 397 | 1935 | 39 | ABCB4,ANGPTL4,AP3D1,ATP6V1B2,BCL6,BDKRB1,CACNA1A,CALCB,CD55,CHMP2B,CX3CL1,EPAS1,FGGY,FOXK1,HDAC3,HEXB,HNF1A,ITGB3,LARGE1,LDLR,LIPG,LPAR3,MET,MT1X,NOD2,NPC1,NR4A3,P2RX4,PDK3,PIK3CD,PLCG2,SIRT6,SLC24A2,SLC8B1,SLC9A2,SYK,TBC1D20,TGM2,TSPOAP1 |
| GO_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 1.0e-07 | 1.5e-05 | 397 | 444 | 17 | AKAP12,CACNA1A,CNTN4,CX3CL1,DTNBP1,KCNMB4,KCTD13,NLGN1,NLGN4X,NPTX2,RIMS1,SERPINE2,SHANK2,SLC24A2,SYT7,TACR2,UNC13A |
| GO_REGULATION_OF_SYSTEM_PROCESS | 2.0e-07 | 1.6e-05 | 397 | 614 | 20 | ADRA2C,CACNB4,DOCK4,EPAS1,ERRFI1,HIP1R,IL10,IL6ST,KCNMB4,NCMAP,NLGN1,NLGN4X,NPTX2,NR4A3,P2RX4,PDGFB,RIMS1,SHANK2,TACR2,TNNT1 |
| GO_RESPONSE_TO_LIPID | 2.0e-07 | 1.7e-05 | 397 | 930 | 25 | ABCB4,AKAP12,ALDH1A2,BDKRB1,CD55,CX3CL1,ERRFI1,FOS,FOXP2,FZD7,GJB2,IL10,LBP,LDLR,NOD2,NPC1,NR4A3,NTRK3,PDK3,PHEX,PLCG2,PTGES,SASH1,SERPINE1,TRIM25 |
| GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 2.0e-07 | 1.7e-05 | 397 | 1000 | 26 | ADRA2C,AP3D1,BCL6,CX3CL1,FOS,GLIPR2,IL6ST,L1CAM,LPAR3,MAMSTR,NLGN1,NTRK3,P2RX4,PRKCI,RIMS1,RNF112,SERPINE1,SERPINE2,SH3GL3,SHANK2,SOCS3,SYK,SYT17,TBX5,TNFSF9,UNC13A |
| GO_REGULATION_OF_CELL_ACTIVATION | 2.0e-07 | 1.7e-05 | 397 | 619 | 20 | AP3D1,BCL6,BST1,CD55,CRLF2,CX3CL1,EBI3,FGL2,GAB2,IL10,IL6ST,LBP,LDLR,NOD2,NR4A3,PDGFB,SDC4,SERPINE2,SYK,TNFSF9 |
| GO_REGULATION_OF_DEFENSE_RESPONSE | 2.0e-07 | 1.7e-05 | 397 | 804 | 23 | BCL6,BST1,CASP4,CX3CL1,FGL2,IL10,IL6ST,IRF7,LBP,LDLR,MAP3K1,MAPK13,MMP3,NOD2,PLCG2,SERPINE1,SOCS3,SYK,TAB3,TGM2,TMSB4X,TNFAIP6,TREML2 |
| GO_CHEMICAL_HOMEOSTASIS | 2.0e-07 | 1.7e-05 | 397 | 1207 | 29 | ABCB4,ANGPTL4,AP3D1,ATP6V1B2,BDKRB1,CACNA1A,CALCB,CD55,CX3CL1,EPAS1,FOXK1,HEXB,HNF1A,LDLR,LIPG,LPAR3,MET,MT1X,NPC1,P2RX4,PDK3,PLCG2,SIRT6,SLC24A2,SLC8B1,SLC9A2,TBC1D20,TGM2,TSPOAP1 |
| GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 2.0e-07 | 1.8e-05 | 397 | 401 | 16 | AFDN,AP3D1,BCL6,CD55,CX3CL1,EBI3,EDIL3,IL10,IL6ST,MAGI1,NOD2,NR4A3,SDC4,SYK,TGM2,TNFSF9 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 2.0e-07 | 1.7e-05 | 397 | 1880 | 38 | ADRA2C,AKAP12,BCL6,BDKRB1,BMP3,BST1,CBLB,CCL22,CCNA1,CX3CL1,DTNBP1,EHD4,ERRFI1,FZD7,GLIPR2,GPRC5A,HDAC3,IL6ST,ITGB3,LCP2,LPAR3,MAP3K1,MGAT5,MRNIP,NDFIP2,NOD2,NTRK3,PDGFB,SASH1,SDC4,SDR16C5,SOCS3,SPRED3,SYK,TAB3,TCIM,TNIK,UNC5CL |
| GO_IMPORT_INTO_CELL | 2.0e-07 | 1.9e-05 | 397 | 810 | 23 | ARFGAP1,ARHGAP12,CLEC4M,DENND1A,EHD4,GRK3,GRK4,HIP1R,ITGB3,LDLR,MASP1,NEURL3,NLGN1,NLGN4X,NPC1,PLCG2,SERPINE1,SH3GL3,SLC9A2,STON1,SYK,SYT7,TINAGL1 |
| GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | 2.0e-07 | 1.9e-05 | 397 | 259 | 13 | AFDN,AP3D1,BCL6,CD55,CX3CL1,EBI3,IL10,IL6ST,MAGI1,NOD2,NR4A3,SYK,TNFSF9 |
| GO_CELL_CHEMOTAXIS | 2.0e-07 | 1.9e-05 | 397 | 306 | 14 | BST1,CCL22,CX3CL1,DOCK4,IL10,LBP,MET,P2RX4,PDGFB,PIK3CD,SERPINE1,SLC8B1,SYK,TMSB4X |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 2.0e-07 | 2.2e-05 | 397 | 1016 | 26 | ADRA2C,BCL6,CCNA1,FAM50A,FOS,FST,GJB2,GTSF1,HEXB,KDM1B,MYCBPAP,OSBP2,PACRG,PI3,RIMS1,SERPINE2,SLCO4C1,SPIRE1,TBC1D20,TEKT3,TEX19,TIMP1,TNFAIP6,TSSK4,TTC21A,TUBB8 |
| GO_REGULATION_OF_CELL_ADHESION | 2.0e-07 | 2.2e-05 | 397 | 695 | 21 | AFDN,AP3D1,BCL6,BST1,CD55,CX3CL1,EBI3,EDIL3,FGL2,FZD7,IL10,IL6ST,MAGI1,NOD2,NR4A3,SDC4,SERPINE1,SERPINE2,SYK,TGM2,TNFSF9 |
| GO_REGULATION_OF_CELL_CELL_ADHESION | 2.0e-07 | 2.3e-05 | 397 | 411 | 16 | AFDN,AP3D1,BCL6,CD55,CX3CL1,EBI3,FGL2,IL10,IL6ST,MAGI1,NOD2,NR4A3,SDC4,SERPINE2,SYK,TNFSF9 |
| GO_SYNAPSE_ORGANIZATION | 3.0e-07 | 2.5e-05 | 397 | 414 | 16 | ARHGAP22,CACNB4,CHMP2B,CNKSR2,CX3CL1,FLRT2,IL10,L1CAM,NGEF,NLGN1,NLGN4X,NTRK3,PDLIM5,RAB39B,SHANK2,UNC13A |
| GO_RESPONSE_TO_PEPTIDE | 3.0e-07 | 2.6e-05 | 397 | 525 | 18 | ATP6V1B2,CACNA1A,CASP4,ERRFI1,GJB2,IL10,IRF5,MMP3,NOD2,NR4A3,PHEX,PRKCI,PTPRE,RAB10,SH2B2,SOCS3,TBC1D4,TIMP1 |
| GO_DEFENSE_RESPONSE | 3.0e-07 | 2.7e-05 | 397 | 1765 | 36 | BCL6,BDKRB1,BST1,CASP4,CCL22,CD55,CLEC4M,CX3CL1,FGL2,FOS,IL10,IL6ST,IRF5,IRF7,ISG20,LBP,LDLR,MAP3K1,MAPK13,MASP1,MMP3,NAIP,NOD2,PIK3CD,PLCG2,PTGES,SERPINE1,SOCS3,SYK,TAB3,TGM2,TIMP1,TMSB4X,TNFAIP6,TREML2,TRIM25 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 5.0e-07 | 4.3e-05 | 397 | 1724 | 35 | ADRA2C,AKAP12,BCL6,BMP3,CASP4,CCL22,CX3CL1,EBI3,EHD4,FZD7,GLIPR2,GPRC5A,HDAC3,HIP1R,IL6ST,ITGB3,LBP,LCP2,LDLR,LPAR3,MAP3K1,MRNIP,NDFIP2,NOD2,NTRK3,PDGFB,SASH1,SDC4,SDR16C5,SOCS3,SYK,TAB3,TCIM,TNIK,UNC5CL |
| GO_VESICLE_ORGANIZATION | 5.0e-07 | 4.4e-05 | 397 | 330 | 14 | AP3D1,CHMP2B,CHMP4C,DTNBP1,PRKCI,SDC4,SERPINE2,SYT7,TBC1D20,TBC1D4,TSNARE1,UNC13A,VPS37B,WASHC4 |
| GO_NERVOUS_SYSTEM_PROCESS | 7.0e-07 | 5.9e-05 | 397 | 1441 | 31 | ADRA2C,AGTPBP1,BDKRB1,CHMP2B,CRX,EPAS1,FOS,FOXP2,GJB2,HEXB,IL10,KCNMB4,LDLR,MYO3B,NCMAP,NLGN1,NLGN4X,NPTX2,NR4A3,NTRK3,OR10A2,OR4D1,OR8A1,OR8D4,P2RX4,RIMS1,SERPINE2,SHANK2,SLC24A2,TACR2,ZNF354A |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 7.0e-07 | 5.9e-05 | 397 | 1220 | 28 | ABCB4,BCL6,CX3CL1,FLRT2,HIP1R,L1CAM,LPAR3,MET,MMP3,NLGN1,NTRK3,PDGFB,PLCG2,PRKCI,RALA,RIMS1,SDC4,SDR16C5,SERPINE1,SHANK2,SIRT6,SPIRE1,SYK,SYT17,SYT7,TPPP,UNC13A,VASP |
| GO_CYTOKINE_PRODUCTION | 7.0e-07 | 5.9e-05 | 397 | 808 | 22 | AKAP12,BCL6,CD55,CRLF2,CX3CL1,EBI3,ERRFI1,IL10,IL6ST,IRF5,IRF7,LBP,LCP2,MAPK13,NOD2,NR4A3,PIK3CD,PLCG2,SERPINE1,SYK,TMSB4X,TRIM25 |
| GO_REGULATION_OF_GLIOGENESIS | 7.0e-07 | 5.9e-05 | 397 | 124 | 9 | CX3CL1,DAAM2,IL6ST,LDLR,NTRK3,P2RX4,PRKCI,RNF112,SERPINE2 |
| GO_EPITHELIUM_DEVELOPMENT | 7.0e-07 | 5.9e-05 | 397 | 1296 | 29 | AFDN,ALDH1A2,ARHGAP12,CBR1,DSC1,ERRFI1,FOXP2,FST,FZD7,GZF1,HEY1,IL10,KRT15,KRT79,MET,NTRK3,PDGFB,PI3,RAB10,RALA,SDC4,SERPINE1,SERPINE2,SIRT6,SOCS3,TBC1D20,TBX5,TGM2,VASP |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 8.0e-07 | 6.3e-05 | 397 | 748 | 21 | CNTN4,DTNBP1,FLRT2,FZD7,GAB2,ITGB3,L1CAM,LPAR3,MET,NGEF,NLGN1,NR4A3,NTRK3,PDLIM5,PIK3CD,RAB10,SHANK2,TBC1D20,TNIK,VASP,ZSWIM6 |
| GO_TRANSMEMBRANE_TRANSPORT | 8.0e-07 | 6.3e-05 | 397 | 1604 | 33 | ABCB4,ADD3,ANKH,ANO7,ATP6V1B2,BDKRB1,CACNA1A,CACNB4,CX3CL1,GJB2,HNF1A,KCNA7,KCNF1,KCNMB4,MID1IP1,NLGN1,NR4A3,P2RX4,PLCG2,PRKCI,RRAD,SHANK2,SIRT6,SLC19A3,SLC24A2,SLC25A4,SLC35E4,SLC8B1,SLC9A2,SLCO4C1,TMSB4X,TSPAN13,TTYH1 |
| GO_COAGULATION | 8.0e-07 | 6.3e-05 | 397 | 343 | 14 | ADRA2C,DOCK6,DOCK9,DTNBP1,GNA12,ITGB3,LCP2,P2RX4,PDGFB,PLCG2,SERPINE1,SERPINE2,SH2B2,SYK |
| GO_INTERACTION_WITH_HOST | 8.0e-07 | 6.5e-05 | 397 | 204 | 11 | CD55,CHMP2B,CHMP4C,CLEC4M,ITGB3,LDLR,MET,NPC1,NTRK3,TRIM25,VPS37B |
| GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | 9.0e-07 | 6.7e-05 | 397 | 164 | 10 | DTNBP1,KCTD13,NLGN1,RIMS1,SERPINE2,SHANK2,SLC24A2,SYT7,TACR2,UNC13A |
| GO_POSITIVE_REGULATION_OF_NEUROTRANSMITTER_SECRETION | 9.0e-07 | 6.9e-05 | 397 | 23 | 5 | DTNBP1,NLGN1,SYT7,TACR2,UNC13A |
| GO_CELL_PART_MORPHOGENESIS | 9.0e-07 | 6.9e-05 | 397 | 691 | 20 | CNTN4,DTNBP1,FLRT2,GAB2,L1CAM,LPAR3,NGEF,NLGN1,NR4A3,NTRK3,PDLIM5,PIK3CD,RAB10,RIMS1,SHANK2,SYT17,TNIK,UNC13A,VASP,ZSWIM6 |
| GO_REGULATION_OF_ENDOCYTOSIS | 1.1e-06 | 8.4e-05 | 397 | 210 | 11 | ARFGAP1,EHD4,HIP1R,ITGB3,NLGN1,PLCG2,SERPINE1,SH3GL3,STON1,SYK,SYT7 |
| GO_PEPTIDE_SECRETION | 1.2e-06 | 8.9e-05 | 397 | 641 | 19 | ADRA2C,AKAP12,ARFIP1,CACNA1A,CRLF2,CX3CL1,HNF1A,ICA1,IL10,LCP2,NOD2,RAB10,RHBDF2,SLC25A4,SLC8B1,SYK,SYT7,TACR2,TMSB4X |
| GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 1.2e-06 | 8.8e-05 | 397 | 767 | 21 | ACAP1,AFDN,ARFGAP1,ARHGAP12,ARHGAP22,ARHGAP32,CASP4,CCL22,CX3CL1,DENND1A,DOCK4,DOCK9,ERRFI1,HIP1R,NTRK3,RGS11,RGS20,RIC1,SYK,TBC1D20,TBC1D4 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 1.3e-06 | 9.3e-05 | 397 | 1187 | 27 | AP3D1,BCL6,BDKRB1,BST1,CD55,CRLF2,CX3CL1,EBI3,FOS,GAB2,IL10,IL6ST,IRF7,LBP,LCP2,MAP3K1,MASP1,NOD2,NR4A3,P2RX4,PIK3CD,PLCG2,SERPINE1,SH2B2,SYK,TAB3,TNFSF9 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 1.3e-06 | 9.1e-05 | 397 | 643 | 19 | CX3CL1,IL6ST,IRF7,LBP,LDLR,MAP3K1,MAPK13,MET,NOD2,NTRK3,P2RX4,PDGFB,PLCG2,SASH1,SERPINE1,SYK,TAB3,TGM2,TMSB4X |
| GO_REGULATION_OF_CELL_POPULATION_PROLIFERATION | 1.3e-06 | 9.0e-05 | 397 | 1716 | 34 | ALDH1A2,BCL6,BST1,CD55,CHST11,CRLF2,CX3CL1,DHCR7,EBI3,EGFL7,ERRFI1,FOXP2,FZD7,GAB2,IL10,IL6ST,ITGB3,MVD,NOD2,NR4A3,NTRK3,PDGFB,PRKCI,PTGES,SAT1,SDC4,SERPINE2,SIRT6,SQLE,SYK,TBX5,TGM2,TIMP1,TNFSF9 |
| GO_REGULATION_OF_MAPK_CASCADE | 1.3e-06 | 9.0e-05 | 397 | 769 | 21 | ADRA2C,AKAP12,BMP3,CCL22,CX3CL1,DTNBP1,ERRFI1,FZD7,GLIPR2,HDAC3,LPAR3,MAP3K1,NOD2,NTRK3,PDGFB,SASH1,SPRED3,SYK,TAB3,TNIK,UNC5CL |
| GO_LIPID_BIOSYNTHETIC_PROCESS | 1.4e-06 | 9.6e-05 | 397 | 710 | 20 | ALDH1A2,CBR1,DHCR7,ELOVL7,HEXB,HSD17B7,LARGE1,LDLR,LTA4H,MID1IP1,MTMR14,MVD,PDGFB,PIGH,PIK3CD,PLCG2,PTGES,SDR42E1,SQLE,TSPOAP1 |
| GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | 1.4e-06 | 9.3e-05 | 397 | 358 | 14 | AKAP12,BDKRB1,CD55,CX3CL1,FOS,GJB2,IL10,IRF5,LBP,NOD2,PLCG2,PTGES,SASH1,SERPINE1 |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 1.5e-06 | 1.0e-04 | 397 | 650 | 19 | BST1,CD55,CRLF2,CX3CL1,DSC1,FGL2,GAB2,HEXB,IL10,LBP,LCP2,LDLR,LTA4H,NR4A3,PIK3CD,RAB10,SLCO4C1,SYK,TNFAIP6 |
| GO_LIPID_LOCALIZATION | 1.6e-06 | 1.1e-04 | 397 | 417 | 15 | ABCB4,ANO7,HEXB,ITGB3,LBP,LDLR,LIPG,MID1IP1,NPC1,OSBP2,P2RX4,PLTP,SQLE,SYK,SYT7 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 1.8e-06 | 1.2e-04 | 397 | 1135 | 26 | ATP6V1B2,CACNA1A,CASP4,DTNBP1,ERRFI1,FOS,GJB2,IL10,IRF5,LDLR,MAPK13,MMP3,NOD2,NPC1,NR4A3,P2RX4,PHEX,PRKCI,PTPRE,RAB10,SH2B2,SOCS3,SYK,TBC1D4,TIMP1,TRIM25 |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 1.9e-06 | 1.2e-04 | 397 | 1064 | 25 | ALDH1A2,CBR1,CYP27C1,ELOVL7,FAAH,HEXB,LARGE1,LDLR,LIPG,LTA4H,MID1IP1,MTMR14,MVD,NOD2,NR4A3,PDGFB,PDK3,PDP1,PIGH,PIK3CD,PLCG2,PTGES,SDC4,SDR16C5,SOCS3 |
| GO_TUBE_MORPHOGENESIS | 2.0e-06 | 1.3e-04 | 397 | 928 | 23 | AMOTL1,ANGPTL4,ARHGAP22,CX3CL1,EGFL7,EPAS1,GZF1,HEY1,IL10,ITGB3,LDLR,MET,NR4A3,RALA,SASH1,SAT1,SDC4,SERPINE1,SIRT6,SYK,TBX5,TGM2,VASP |
| GO_TISSUE_MORPHOGENESIS | 2.3e-06 | 1.5e-04 | 397 | 670 | 19 | ALDH1A2,ARHGAP12,EYA2,FST,FZD7,GZF1,HEY1,IL10,ITGB3,MET,NR4A3,RAB10,RALA,SDC4,SIRT6,SOCS3,TBX5,TGM2,VASP |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 2.4e-06 | 1.5e-04 | 397 | 671 | 19 | AKR1A1,B3GNT7,CHST11,CHST15,CSGALNACT2,ELOVL7,FUT4,GMDS,LARGE1,MGAT5,MVD,NME7,NPC1,PDGFB,PDK3,PDP1,PIGH,SDC4,TMSB4X |
| GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | 2.4e-06 | 1.5e-04 | 397 | 107 | 8 | BCL6,EGFL7,HEY1,IL6ST,MAML3,NOD2,PRKCI,TCIM |
| GO_ENDOSOMAL_TRANSPORT | 2.5e-06 | 1.6e-04 | 397 | 228 | 11 | AP3D1,CHMP2B,CHMP4C,DENND1A,EHD4,LRRC1,RAB10,RIC1,TINAGL1,VPS37B,WASHC4 |
| GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 2.5e-06 | 1.6e-04 | 397 | 378 | 14 | ADRA2C,BCL6,CX3CL1,L1CAM,LPAR3,NLGN1,NTRK3,PRKCI,RIMS1,RNF112,SH3GL3,SHANK2,SYT17,UNC13A |
| GO_REGULATION_OF_KINASE_ACTIVITY | 2.5e-06 | 1.6e-04 | 397 | 872 | 22 | ADRA2C,CBLB,CCNA1,DTNBP1,ERRFI1,GPRC5A,ITGB3,LCP2,LPAR3,MAP3K1,MRNIP,NOD2,NTRK3,PDGFB,SASH1,SDC4,SOCS3,SPRED3,SYK,TAB3,TCIM,TNIK |
| GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 2.8e-06 | 1.7e-04 | 397 | 810 | 21 | ALDH1A2,AMOTL1,ANGPTL4,ARHGAP22,CX3CL1,DHCR7,EGFL7,EPAS1,ERRFI1,HEY1,IL10,ITGB3,LDLR,PDGFB,SASH1,SAT1,SERPINE1,SIRT6,SOCS3,SYK,TBX5 |
| GO_CELLULAR_RESPONSE_TO_LIPID | 2.8e-06 | 1.7e-04 | 397 | 615 | 18 | ABCB4,ALDH1A2,CD55,CX3CL1,ERRFI1,FZD7,GJB2,IL10,LBP,LDLR,NOD2,NPC1,NR4A3,NTRK3,PDK3,PHEX,SASH1,SERPINE1 |
| GO_LEUKOCYTE_MIGRATION | 3.4e-06 | 2.1e-04 | 397 | 502 | 16 | BDKRB1,BST1,CCL22,CEACAM5,CX3CL1,IL10,ITGB3,L1CAM,LBP,P2RX4,PDGFB,PIK3CD,SDC4,SERPINE1,SLC8B1,SYK |
| GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 3.4e-06 | 2.1e-04 | 397 | 562 | 17 | ADRA2C,BCL6,CX3CL1,IL6ST,L1CAM,LPAR3,NLGN1,NTRK3,P2RX4,PRKCI,RIMS1,RNF112,SERPINE2,SH3GL3,SHANK2,SYT17,UNC13A |
| GO_NOTCH_SIGNALING_PATHWAY | 3.8e-06 | 2.3e-04 | 397 | 193 | 10 | BCL6,DTX2,EGFL7,GMDS,HEY1,IL6ST,MAML3,NOD2,PRKCI,TCIM |
| GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION | 4.1e-06 | 2.4e-04 | 397 | 394 | 14 | AP3D1,BCL6,BST1,CD55,CRLF2,EBI3,GAB2,IL10,IL6ST,LBP,NOD2,NR4A3,SYK,TNFSF9 |
| GO_LEUKOCYTE_CELL_CELL_ADHESION | 4.5e-06 | 2.6e-04 | 397 | 343 | 13 | AP3D1,BCL6,CD55,CLEC4M,EBI3,FGL2,IL10,IL6ST,NOD2,NR4A3,SDC4,SYK,TNFSF9 |
| GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 4.5e-06 | 2.6e-04 | 397 | 974 | 23 | ADRA2C,AKAP12,BMP3,CCL22,CX3CL1,DTNBP1,ERRFI1,FZD7,GLIPR2,HDAC3,LPAR3,MAP3K1,MAPK13,MET,NOD2,NTRK3,PDGFB,SASH1,SPRED3,SYK,TAB3,TNIK,UNC5CL |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 4.6e-06 | 2.7e-04 | 397 | 976 | 23 | ADRA2C,CBLB,CCNA1,DTNBP1,ERRFI1,GPRC5A,ITGB3,LCP2,LPAR3,MAP3K1,MRNIP,NOD2,NTRK3,PDGFB,SASH1,SDC4,SOCS3,SPRED3,SYK,TAB3,TCIM,TMSB4X,TNIK |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 4.7e-06 | 2.7e-04 | 397 | 1988 | 36 | AKAP12,ARNTL2,CITED4,CRX,CX3CL1,EBI3,EPAS1,FOS,FOXK1,FZD7,HDAC3,HEXB,HEY1,HNF1A,IL10,IRF5,IRF7,KCTD13,KDM1B,LBP,LDLR,MAML3,MAMSTR,MET,MID1IP1,NFIL3,NOD2,NR4A3,P2RX4,PDGFB,SERPINE1,SIRT7,SYK,TBX5,TMSB4X,ZBTB18 |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 4.8e-06 | 2.8e-04 | 397 | 1051 | 24 | ATP6V1B2,BMP3,CBLB,CHST11,ERRFI1,FLRT2,FOS,FST,GAB2,GPRC5A,HIP1R,IL6ST,ITGB3,LCP2,MET,NGEF,NR4A3,NTRK3,PDGFB,PTPRE,RHBDF2,SH2B2,SOCS3,SYK |
| GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 5.4e-06 | 3.1e-04 | 397 | 777 | 20 | CD55,CHMP2B,CHMP4C,CX3CL1,FGL2,IRF7,ISG20,LBP,MAP3K1,NOD2,PLCG2,SASH1,SOCS3,SYK,TAB3,TBC1D20,TIMP1,TREML2,TRIM25,VPS37B |
| GO_SEXUAL_REPRODUCTION | 5.6e-06 | 3.1e-04 | 397 | 847 | 21 | BCL6,CCNA1,FAM50A,FST,GTSF1,HEXB,KDM1B,MYCBPAP,OSBP2,PACRG,PI3,RIMS1,SERPINE2,SLCO4C1,SPIRE1,TBC1D20,TEX19,TNFAIP6,TSSK4,TTC21A,TUBB8 |
| GO_RESPONSE_TO_DRUG | 5.7e-06 | 3.2e-04 | 397 | 1061 | 24 | ABCB4,DTNBP1,ERRFI1,FOS,GJB2,GNA12,IL10,IRF5,MAPK13,MET,MMP3,NOD2,NPC1,NR4A3,NTRK3,P2RX4,PDGFB,RNF112,SLC19A3,SLC25A4,SLC35F3,SYT17,SYT7,TACR2 |
| GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 5.9e-06 | 3.3e-04 | 397 | 1364 | 28 | ADRA2C,AKAP12,BDKRB1,CALCB,CCL22,CX3CL1,FZD7,GNA12,GNRH2,GPR160,GPRC5A,GRK3,GRK4,HEBP1,LPAR3,MET,MRGPRX3,NGEF,OBSCN,OR10A2,OR4D1,OR8A1,OR8D4,RGS11,RGS20,TACR2,TGM2,TMEM145 |
| GO_MULTICELLULAR_ORGANISM_REPRODUCTION | 6.2e-06 | 3.4e-04 | 397 | 853 | 21 | BCL6,CCNA1,FAM50A,FST,GJB2,GTSF1,HEXB,KDM1B,MYCBPAP,OSBP2,PACRG,SERPINE2,SLCO4C1,SPIRE1,TBC1D20,TEKT3,TEX19,TNFAIP6,TSSK4,TTC21A,TUBB8 |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 6.5e-06 | 3.5e-04 | 397 | 468 | 15 | AKAP12,CRLF2,CX3CL1,EBI3,IL10,IL6ST,IRF5,IRF7,LBP,MAPK13,NOD2,NR4A3,PLCG2,SERPINE1,SYK |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 6.7e-06 | 3.7e-04 | 397 | 592 | 17 | CNTN4,DTNBP1,FLRT2,GAB2,L1CAM,LPAR3,NGEF,NLGN1,NR4A3,NTRK3,PDLIM5,PIK3CD,RAB10,SHANK2,TNIK,VASP,ZSWIM6 |
| GO_MAST_CELL_ACTIVATION | 6.9e-06 | 3.7e-04 | 397 | 58 | 6 | CRLF2,GAB2,LCP2,NR4A3,PIK3CD,SYK |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 6.9e-06 | 3.7e-04 | 397 | 723 | 19 | AKR1A1,ALDH1A2,CBR1,CHST15,DHCR7,ELOVL7,FOXK1,HSD17B7,LTA4H,MID1IP1,MVD,NME7,NUDT10,PDGFB,PLCG2,PLTP,PTGES,SQLE,SYK |
| GO_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | 7.0e-06 | 3.7e-04 | 397 | 254 | 11 | ABCB4,ADRA2C,DTNBP1,ITGB3,LDLR,LIPG,NPC1,PLTP,SYK,SYT17,SYT7 |
| GO_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS | 7.1e-06 | 3.7e-04 | 397 | 34 | 5 | AKAP12,ERRFI1,IL10,LBP,SYK |
| GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | 7.2e-06 | 3.7e-04 | 397 | 414 | 14 | ABCB4,ANGPTL4,DHCR7,HDAC3,LDLR,MID1IP1,MVD,NOD2,NR4A3,PDGFB,PDK3,PDP1,SOCS3,SQLE |
| GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 7.2e-06 | 3.7e-04 | 397 | 725 | 19 | ATP6V1B2,CBLB,ERRFI1,FLRT2,GAB2,GPRC5A,HIP1R,ITGB3,LCP2,MET,NGEF,NR4A3,NTRK3,PDGFB,PTPRE,RHBDF2,SH2B2,SOCS3,SYK |
| GO_CELL_PROJECTION_ORGANIZATION | 8.0e-06 | 4.1e-04 | 397 | 1545 | 30 | ATCAY,CFAP73,CNTN4,CX3CL1,DTNBP1,FGD6,FLRT2,GAB2,L1CAM,LPAR3,NGEF,NLGN1,NR4A3,NTRK3,PDLIM5,PIK3CD,PRKCI,RAB10,RALA,RIMS1,SDC4,SHANK2,SYT17,TEKT3,TNIK,TTC21A,TTYH1,UNC13A,VASP,ZSWIM6 |
| GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 8.7e-06 | 4.4e-04 | 397 | 1163 | 25 | ANGPTL4,BCL6,CX3CL1,FGD6,FOXP2,FZD7,GNA12,HEXB,HEY1,IL10,L1CAM,LPAR3,NGEF,NLGN1,NTRK3,PDLIM5,RIMS1,SASH1,SERPINE1,SIRT6,SYT17,TBX5,TNIK,UNC13A,ZSWIM6 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 8.8e-06 | 4.5e-04 | 397 | 1164 | 25 | AKR1A1,ALDH1A2,ATCAY,B3GNT7,CBR1,CHST11,CHST15,CSGALNACT2,CYP27C1,ELOVL7,FAAH,FOXK1,GSTO2,HEXB,LTA4H,MID1IP1,NPC1,NR4A3,PDGFB,PDK3,PDP1,PRUNE2,PTGES,SIRT6,SYK |
| GO_POSTSYNAPSE_ORGANIZATION | 8.9e-06 | 4.5e-04 | 397 | 168 | 9 | ARHGAP22,CHMP2B,CNKSR2,NGEF,NLGN1,NLGN4X,NTRK3,PDLIM5,SHANK2 |
| GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 9.0e-06 | 4.5e-04 | 397 | 1318 | 27 | ADRA2C,BCL6,CNTN4,CX3CL1,DAAM2,DOCK4,ERRFI1,FGL2,FZD7,HEY1,IL10,LBP,LDLR,NGEF,NLGN1,NLGN4X,NTRK3,P2RX4,PDGFB,SERPINE1,SERPINE2,TACR2,TBX5,TIMP1,TMSB4X,TNNT1,TRIM25 |
| GO_MEMBRANE_ORGANIZATION | 9.1e-06 | 4.5e-04 | 397 | 875 | 21 | ABCB4,ANO7,AP3D1,ARHGAP12,CHMP2B,CHMP4C,EYA2,HIP1R,LDLR,MPV17L,NLGN1,NLGN4X,NPC1,PRKCI,RALA,RIMS1,SPIRE1,SYT7,TBC1D20,TBC1D4,TSNARE1 |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 9.1e-06 | 4.5e-04 | 397 | 737 | 19 | AKAP12,ALDH1A2,BCL6,CASP4,FOS,HIP1R,IL10,IRF5,MMP3,NGEF,NR4A3,NTRK3,OBSCN,PIK3CD,PRKCI,STK17A,STK17B,SYK,TGM2 |
| GO_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 9.8e-06 | 4.8e-04 | 397 | 170 | 9 | ADRA2C,CBLB,ERRFI1,GPRC5A,IL10,NLGN1,NPTX2,SERPINE1,SHANK2 |
| GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 1.0e-05 | 4.9e-04 | 397 | 1175 | 25 | ALDH1A2,AMOTL1,ANGPTL4,ARHGAP22,CX3CL1,DHCR7,EGFL7,EPAS1,ERRFI1,FLRT2,FZD7,HEY1,IL10,ITGB3,LDLR,NTRK3,PDGFB,PDLIM5,SASH1,SAT1,SERPINE1,SIRT6,SOCS3,SYK,TBX5 |
| GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 1.0e-05 | 4.9e-04 | 397 | 548 | 16 | ADRA2C,AKAP12,CCL22,CX3CL1,FZD7,GLIPR2,LPAR3,MAP3K1,NOD2,NTRK3,PDGFB,SASH1,SYK,TAB3,TNIK,UNC5CL |
| GO_REGULATION_OF_CHEMOTAXIS | 1.0e-05 | 4.9e-04 | 397 | 216 | 10 | BST1,LBP,MET,NTRK3,P2RX4,PDGFB,SERPINE1,SLC8B1,TMSB4X,ZSWIM6 |
| GO_REGULATION_OF_EXOCYTOSIS | 1.0e-05 | 4.9e-04 | 397 | 216 | 10 | DTNBP1,GAB2,NLGN1,RAB10,RALA,RIMS1,SDC4,SYK,SYT17,SYT7 |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 1.0e-05 | 5.0e-04 | 397 | 1567 | 30 | AKAP12,BDKRB1,CASP4,CCL22,CD55,CLEC4M,CX3CL1,FGL2,FOS,GJB2,IL10,IRF5,IRF7,ISG20,LBP,MAP3K1,MASP1,NAIP,NOD2,PI3,PIK3CD,PLCG2,PTGES,SASH1,SERPINE1,SOCS3,SYK,TAB3,TREML2,TRIM25 |
Num: 8 (Pathways: 86 DK: 2)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (2) | MKNK2, NIM1K |
| Light Kinase (5) | DYRK1A, MAP3K2, PDK1, PRKAA2, TEC |
| Non-kinase Count | 390 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_RESPONSE_TO_OXYGEN_LEVELS | 0.0e+00 | 0.0e+00 | 397 | 391 | 32 | ADAM15,ADAM8,AK4,ALKBH5,ANG,ATP6V1A,BACH1,BNIP3,BNIP3L,CA9,EGLN1,EGLN3,ENO1,ERO1A,FAM162A,HILPDA,LDHA,LOXL2,MGARP,NDRG1,NOL3,P4HB,PDK1,PGF,PGK1,PKM,PLOD1,POLG,PSMB4,RBPJ,TM9SF4,VEGFD |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 0.0e+00 | 0.0e+00 | 397 | 1235 | 52 | ACADVL,ADAM15,ADAM8,AK4,AKR1B1,ALKBH5,ANG,ARPP21,ATP2B1,ATP6V1A,BACH1,BNIP3,BNIP3L,CA9,CDKN2D,CEP250,DDHD2,EGLN1,EGLN3,ENO1,ERO1A,FAM162A,FECH,HILPDA,KIAA0319,LDHA,LOXL2,MAP3K2,MGARP,NDRG1,NHEJ1,NMU,NOL3,P4HB,PAPPA2,PDE2A,PDK1,PGF,PGK1,PKD1,PKM,PLOD1,POLG,PSMB4,RBPJ,RELA,SAG,TM9SF4,TRIM32,VCP,VEGFD,ZNF516 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 1005 | 44 | ACADVL,AKR1B1,AKR1B10,ALDOA,ALKBH5,ASPH,BCKDHA,BNIP3,COX6B1,CYP4F11,EGLN1,EGLN3,ENO1,ENO2,ERO1A,ETFA,FADS1,GAPDH,GLRX,GPI,HSD17B12,KCNAB1,KDM5C,LDHA,LOXL2,ME1,NDUFA6,NDUFA8,P4HB,PGD,PGK1,PIR,PKM,PLOD1,POR,PPP1R3C,PPP1R3E,PRDX1,RSBN1,TALDO1,TKT,TPI1,VCP,VKORC1 |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 0.0e+00 | 397 | 532 | 32 | ACADVL,AK4,AKR1B1,ALDOA,ASPH,BNIP3,COX6B1,ENO1,ENO2,ETFA,FECH,GAPDH,GLRX,GPI,LDHA,LOXL2,ME1,NDUFA6,NDUFA8,OGT,PFKFB4,PGD,PGK1,PKM,POR,PPP1R3C,PPP1R3E,PRKAA2,TALDO1,TKT,TPI1,VCP |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | 0.0e+00 | 0.0e+00 | 397 | 233 | 21 | ADAM8,AK4,ATP6V1A,BACH1,BNIP3,BNIP3L,CA9,EGLN1,EGLN3,ENO1,ERO1A,FAM162A,HILPDA,MGARP,NDRG1,NOL3,P4HB,PDK1,PGK1,PSMB4,RBPJ |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 1962 | 53 | ACADVL,AK4,AKR1B1,AKR1B10,ALDOA,B3GNT4,BCKDHA,CHSY1,CYP4F11,EGF,ENO1,ENO2,ENTPD1,ERO1A,ETFA,FADS1,GAPDH,GGT1,GLRX,GNE,GPI,GSTP1,HSD17B12,IDS,IGFBP3,IPMK,LDHA,ME1,OGT,PDE2A,PDK1,PFKFB4,PGD,PGK1,PIAS4,PKM,PLA2G4D,PLOD1,POR,PPP1R3E,PRKAA2,PRPSAP2,PSMB4,SEPSECS,SLC2A3,SLC6A8,TALDO1,TKT,TPI1,UGT2B4,UPRT,VCP,VKORC1 |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 1164 | 37 | ACADVL,ALDOA,B3GNT4,BCKDHA,CHSY1,CYP4F11,EGF,ENO1,ENO2,ERO1A,ETFA,FADS1,GAPDH,GGT1,GNE,GPI,GSTP1,HSD17B12,IDS,LDHA,ME1,OGT,PDK1,PFKFB4,PGD,PGK1,PKM,PLA2G4D,PLOD1,POR,PRKAA2,PSMB4,SEPSECS,SLC2A3,SLC6A8,TPI1,UGT2B4 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 620 | 27 | AKR1B1,ALDOA,B3GNT4,EGF,ENO1,ENO2,GANAB,GAPDH,GNE,GPI,IGFBP3,LDHA,ME1,OGT,PDK1,PFKFB4,PGD,PGK1,PKM,PPP1R3C,PPP1R3E,PRKAA2,SLC2A3,TALDO1,TKT,TPI1,UGT2B4 |
| GO_MONOSACCHARIDE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 292 | 19 | AKR1B1,ALDOA,ENO1,ENO2,GAPDH,GPI,IGFBP3,OGT,PDK1,PFKFB4,PGD,PGK1,PKM,PPP1R3E,SLC2A3,TALDO1,TKT,TPI1,UGT2B4 |
| GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 0.0e+00 | 0.0e+00 | 397 | 1258 | 37 | ASPH,CASS4,CHD5,DYRK1A,EGF,EGLN1,EGLN3,ESCO1,FKBP15,GAPDH,IRGM,ITGA5,LOXL2,MAGEA2B,MKNK2,MORF4L1,NAA30,NCOA3,OGT,P4HB,PIAS4,PKD1,PLOD1,POR,PRKAA2,RAB6A,RASSF2,RELA,RLF,RPN2,SMYD2,TEC,TRIM16,VCP,VKORC1,YEATS2,ZNF274 |
| GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 211 | 16 | AKR1B1,ALDOA,B3GNT4,EGF,ENO1,ENO2,GAPDH,GPI,OGT,PGD,PGK1,PPP1R3C,PPP1R3E,TALDO1,TKT,TPI1 |
| GO_ADP_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 122 | 13 | AK4,ALDOA,ENO1,ENO2,GAPDH,GPI,LDHA,OGT,PFKFB4,PGK1,PKM,PRKAA2,TPI1 |
| GO_PYRUVATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 150 | 14 | ALDOA,ENO1,ENO2,GAPDH,GPI,LDHA,ME1,OGT,PDK1,PFKFB4,PGK1,PKM,PRKAA2,TPI1 |
| GO_MONOSACCHARIDE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 99 | 12 | AKR1B1,ALDOA,ENO1,ENO2,GAPDH,GPI,OGT,PGD,PGK1,TALDO1,TKT,TPI1 |
| GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 654 | 26 | ACADVL,ALDOA,CYP4F11,ENO1,ENO2,ETFA,FADS1,GAPDH,GGT1,GPI,GSTP1,HSD17B12,LDHA,ME1,OGT,PDK1,PFKFB4,PGD,PGK1,PKM,PLA2G4D,POR,PRKAA2,SLC6A8,TPI1,UGT2B4 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 397 | 1698 | 43 | ADAM15,ADPRHL2,AKR1B1,AKR1B10,ANKZF1,AP3S1,ATP2B1,ATP6V1A,BAIAP3,BNIP3,CA9,CACNB1,CD68,CDC73,CDKN2D,EGLN1,FECH,GGT1,GSTP1,IRGM,KLF7,LDHA,ME1,MGARP,NCOA3,OGT,OR56A1,PDE2A,PKM,POLG,POR,PRDX1,PRKAA2,PXN,RARA,RELA,RGS2,RRAGD,RXRB,TLR6,TRIM16,UPRT,VCP |
| GO_NADH_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 41 | 9 | ALDOA,ENO1,ENO2,GAPDH,GPI,PGK1,PKM,TPI1,VCP |
| GO_GLYCOLYTIC_PROCESS_THROUGH_FRUCTOSE_6_PHOSPHATE | 0.0e+00 | 0.0e+00 | 397 | 28 | 8 | ALDOA,ENO1,ENO2,GAPDH,GPI,PGK1,PKM,TPI1 |
| GO_ATP_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 397 | 303 | 18 | AK4,ALDOA,ATP6V1A,COX6B1,ENO1,ENO2,GAPDH,GPI,LDHA,NDUFA6,NDUFA8,OGT,PFKFB4,PGK1,PKM,PRKAA2,TPI1,VCP |
| GO_NUCLEOTIDE_PHOSPHORYLATION | 0.0e+00 | 0.0e+00 | 397 | 134 | 13 | AK4,ALDOA,ENO1,ENO2,GAPDH,GPI,LDHA,OGT,PFKFB4,PGK1,PKM,PRKAA2,TPI1 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 397 | 1117 | 33 | AK4,AKR1B1,AKR1B10,ALDOA,B3GNT4,CHSY1,EGF,ENO1,ENO2,GANAB,GAPDH,GLTP,GNE,GPI,HSD17B12,IDS,LDHA,MARCHF6,OGT,PDE2A,PDK1,PFKFB4,PGD,PGK1,PKM,PRKAA2,PRPSAP2,RPN2,TALDO1,TKT,TPI1,UPRT,VCP |
| GO_NAD_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 397 | 50 | 9 | ALDOA,ENO1,ENO2,GAPDH,GPI,LDHA,PGK1,PKM,TPI1 |
| GO_GLUCOSE_CATABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 397 | 36 | 8 | ALDOA,ENO1,ENO2,GAPDH,GPI,PGK1,PKM,TPI1 |
| GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 397 | 154 | 13 | AK4,ALDOA,ENO1,ENO2,GAPDH,GPI,LDHA,OGT,PFKFB4,PGK1,PKM,PRKAA2,TPI1 |
| GO_PROTEOLYSIS | 0.0e+00 | 1.0e-07 | 397 | 1779 | 42 | ADAM15,ADAM8,ADAMTS16,AMBP,AMZ2,ANKZF1,ASPH,BCAP31,CDKN2D,EFNA3,EGF,EGLN3,ENO1,F3,FAM162A,FZR1,GAPDH,GGT1,HTRA3,JKAMP,JOSD1,MARCHF6,NOL3,OGT,PAPPA2,PGK1,PKD1,POR,PRSS53,PRSS8,PSMB4,RELA,RNF122,SUFU,TMF1,TPSB2,TRIM32,UBE2O,UBR3,UBR4,VCP,VCPIP1 |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 3.0e-07 | 397 | 1208 | 33 | ADAM15,ADPRHL2,AKR1B1,AKR1B10,ANKZF1,AP3S1,ATP2B1,ATP6V1A,BAIAP3,BNIP3,CACNB1,CD68,CDC73,FECH,GSTP1,IRGM,KLF7,MGARP,NCOA3,OGT,OR56A1,PDE2A,PKM,POLG,POR,PRDX1,PRKAA2,PXN,RARA,RELA,RRAGD,TLR6,VCP |
| GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 3.0e-07 | 397 | 723 | 25 | ACADVL,AKR1B1,ALDOA,CYP4F11,EGF,ENO1,ENO2,FADS1,GAPDH,GGT1,GPI,HSD17B12,IPMK,OGT,PDE2A,PGD,PGK1,PKM,PLOD1,POR,PRKAA2,TALDO1,TKT,TPI1,VCP |
| GO_HOMEOSTATIC_PROCESS | 0.0e+00 | 4.0e-07 | 397 | 1935 | 43 | ABCB6,ACADVL,ADAM8,AKR1B1,ALDOA,ANG,ANO6,ATP2B1,ATP6V1A,BAIAP3,BCAP31,BNIP3,CLIC2,CNNM2,EGLN1,ERO1A,GLRX,GSTP1,H4C8,HCAR2,KLF7,LIME1,MCUB,MLLT11,NMU,NOL3,OGT,OR56A1,P4HB,PKD1,POLG,PRDX1,PRKAA2,RAB20,RASSF2,RBPJ,SGIP1,SMAP1,TM9SF4,TNKS2,TRIM32,TXNDC11,ZNF516 |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 5.0e-07 | 397 | 627 | 23 | AK4,ALDOA,ENO1,ENO2,ENTPD1,GAPDH,GLRX,GNE,GPI,HSD17B12,LDHA,ME1,OGT,PDE2A,PDK1,PFKFB4,PGK1,PKM,PRKAA2,PRPSAP2,TPI1,UPRT,VCP |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 5.0e-07 | 397 | 423 | 19 | AK4,ALDOA,ENO1,ENO2,GAPDH,GPI,HSD17B12,LDHA,OGT,PDE2A,PDK1,PFKFB4,PGK1,PKM,PRKAA2,PRPSAP2,TPI1,UPRT,VCP |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 1.3e-06 | 397 | 1863 | 41 | ADAM8,AMBP,ARHGEF7,AVPI1,BCAP31,CARD14,CDKN2D,CHD5,CLIC2,DIPK2A,DYRK1A,ECT2L,EGF,ENO1,F3,FAM13A,FARP1,GBF1,GSTP1,IGFBP3,ING2,LIME1,MAP3K2,NENF,NLRC3,NOL3,OGT,P4HB,PDE2A,PIAS4,PRDX1,PRKAA2,RASSF2,RELA,RGS2,RRAGD,SMYD2,TLR6,TP53BP2,TRIM32,WLS |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 1.5e-06 | 397 | 1033 | 29 | AK4,ALDOA,DDHD2,ENO1,ENO2,FADS1,GAPDH,GPI,HSD17B12,IPMK,LDHA,ME1,OGT,OSBPL10,PDE2A,PDK1,PFKFB4,PGD,PGK1,PKM,PLA2G4D,PLEKHA2,PRKAA2,PRPSAP2,TALDO1,TKT,TPI1,UPRT,VCP |
| GO_CARBOHYDRATE_CATABOLIC_PROCESS | 0.0e+00 | 1.9e-06 | 397 | 198 | 13 | ALDOA,ENO1,ENO2,GAPDH,GPI,LDHA,OGT,PFKFB4,PGD,PGK1,PKM,PRKAA2,TPI1 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 2.0e-06 | 397 | 1748 | 39 | ADAM8,AKR1B1,ANO6,ARHGEF7,BCAP31,BNIP3,BNIP3L,CARD14,CDC73,CDKN2D,DIPK2A,EGLN3,ENO1,F3,FAM162A,GAPDH,GSTP1,HCAR2,IGFBP3,ING2,ITGA5,LDHA,MLLT11,NDRG1,NOL3,P4HB,PIAS4,POR,PRKAA2,RARA,RASSF2,RELA,RNF122,TLR6,TMF1,TP53BP2,TRIM32,UBE2O,VCP |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 0.0e+00 | 3.2e-06 | 397 | 1781 | 39 | ADAM8,AGAP1,ANG,ARHGEF7,ASPH,AVPI1,BCAP31,CARD14,CASS4,CLIC2,DYNC1I1,EFNA3,EGF,EGLN3,F3,FAM13A,FAM162A,FZR1,GLRX,IRGM,MAGEA2B,MAP3K2,NCOA3,NHEJ1,NPM2,PKD1,POR,RARA,RASSF2,RELA,RGS2,RUNDC1,S100A10,SMAP1,SMAP2,SNX13,TLR6,TRIM32,VCP |
| GO_PEPTIDYL_LYSINE_MODIFICATION | 0.0e+00 | 5.7e-06 | 397 | 397 | 17 | CHD5,ESCO1,LOXL2,MAGEA2B,MORF4L1,NCOA3,OGT,PIAS4,PLOD1,POR,PRKAA2,RELA,RLF,SMYD2,TRIM16,YEATS2,ZNF274 |
| GO_SECRETION | 0.0e+00 | 6.3e-06 | 397 | 1680 | 37 | ADAM8,ALDOA,ANG,ANO6,BAIAP3,CA9,CD68,COPA,DOK3,EGF,EXOC5,GAPDH,GPI,GSTP1,HCAR2,KLF7,NMU,OR56A1,PANX2,PGRMC1,PKM,PPFIA4,RAB6A,RBPJ,RNASET2,SCAMP1,SLC2A3,TLR6,TMF1,TPD52,TRIM16,TVP23C,UBR4,UPRT,VCP,VEGFD,WLS |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 9.2e-06 | 397 | 463 | 18 | AK4,ALDOA,ENO1,ENO2,GAPDH,GPI,HSD17B12,LDHA,OGT,PDE2A,PDK1,PFKFB4,PGK1,PKM,PRKAA2,PRPSAP2,TPI1,VCP |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 9.3e-06 | 397 | 1135 | 29 | AKR1B1,ANKZF1,AP3S1,ATP2B1,ATP6V1A,BCAP31,CACNB1,CD68,EGLN1,GSTP1,JKAMP,LDHA,MARCHF6,MGARP,OGT,OR56A1,PDE2A,PKM,POR,PXN,RELA,RGS2,RRAGD,RTF2,TLR6,TRIM16,UPRT,VCP,VKORC1 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 1.0e-07 | 1.0e-05 | 397 | 1869 | 39 | ADAM8,AKR1B1,AVPI1,BAIAP3,BCAP31,BNIP3,CARD14,CDC73,CHD5,CHSY1,EGF,F3,FAM162A,HCAR2,IGFBP3,ING2,IRGM,ITGA5,MAP3K2,MLLT11,NENF,NMU,PIAS4,POR,PSMB4,RASSF2,RBPJ,RELA,RNF165,RRAGD,TLR6,TMF1,TNKS2,TP53BP2,TRIM16,TRIM32,UBE2O,VCP,WLS |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1.0e-07 | 1.1e-05 | 397 | 1429 | 33 | ADAM8,AGAP1,ANG,ARHGEF7,ASPH,AVPI1,BCAP31,CARD14,CASS4,DYNC1I1,EFNA3,EGF,EGLN3,F3,FAM13A,FAM162A,FZR1,IRGM,MAGEA2B,MAP3K2,NHEJ1,NPM2,PKD1,POR,RASSF2,RGS2,RUNDC1,S100A10,SMAP1,SMAP2,SNX13,TLR6,VCP |
| GO_REGULATION_OF_HYDROLASE_ACTIVITY | 1.0e-07 | 1.1e-05 | 397 | 1287 | 31 | AGAP1,AMBP,ANG,ARHGEF7,ASPH,BCAP31,CDKN2D,DYNC1I1,EFNA3,EGLN1,EGLN3,F3,FAM13A,FAM162A,FARP1,FKBP15,GAPDH,IGFBP3,NOL3,POR,PPME1,RGS2,RUNDC1,S100A10,SAG,SBF2,SMAP1,SMAP2,SNX13,UBE2O,VCP |
| GO_MONOSACCHARIDE_CATABOLIC_PROCESS | 1.0e-07 | 1.1e-05 | 397 | 67 | 8 | ALDOA,ENO1,ENO2,GAPDH,GPI,PGK1,PKM,TPI1 |
| GO_CELLULAR_HOMEOSTASIS | 1.0e-07 | 1.4e-05 | 397 | 963 | 26 | ABCB6,ALDOA,ANO6,ATP2B1,ATP6V1A,BAIAP3,BCAP31,BNIP3,CLIC2,ERO1A,GLRX,KLF7,LIME1,MCUB,NMU,NOL3,OR56A1,P4HB,PKD1,POLG,PRDX1,PRKAA2,RAB20,TM9SF4,TRIM32,TXNDC11 |
| GO_ION_TRANSPORT | 1.0e-07 | 1.8e-05 | 397 | 1692 | 36 | ABCB6,ANO6,ASPH,ATP2B1,ATP6V1A,CA9,CACNB1,CLIC2,CNNM2,COX6B1,EGF,ERO1A,GLRX,GLTP,KCNAB1,LIME1,MCUB,NIPAL3,NOL3,OR56A1,OSBPL10,PANX2,PDE2A,PKD1,PLIN2,PPFIA4,PRELID2,PRKAA2,PRSS8,RGS2,RHCE,SLC22A14,SLC48A1,SLC6A6,SLC6A8,TCAF2 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 1.0e-07 | 1.8e-05 | 397 | 912 | 25 | CDC73,DCAF5,FBXO15,FZR1,H2BC15,HERC3,KCTD9,MAGEA2B,MARCHF6,OGT,PDZD4,PIAS4,PSMB4,RAB40C,RELA,RNF122,RNF165,TNKS2,TRIM32,UBE2O,UBR3,UBR4,VCP,VCPIP1,WSB1 |
| GO_GLUCOSE_METABOLIC_PROCESS | 1.0e-07 | 2.3e-05 | 397 | 210 | 12 | ALDOA,ENO1,ENO2,GAPDH,GPI,IGFBP3,OGT,PDK1,PGK1,PKM,PPP1R3E,TPI1 |
| GO_PROTEIN_CATABOLIC_PROCESS | 2.0e-07 | 3.0e-05 | 397 | 938 | 25 | ADAM8,AMBP,ANKZF1,AP2M1,BCAP31,BNIP3,BNIP3L,EGF,FZR1,JKAMP,MAGEA2B,MARCHF6,OGT,PKD1,PSMB4,RELA,RNF122,RNF165,SUFU,TMF1,TRIM32,UBE2O,UBR3,UBR4,VCP |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 4.0e-07 | 6.7e-05 | 397 | 1870 | 37 | AKNAD1,BACH1,CDC73,CNOT8,CSRNP1,DDX17,DDX41,DYRK1A,EGF,ENO1,ING2,KLF7,MAP3K2,MLLT11,NCOA3,NFATC2,NPM2,OGT,PFKFB4,PKD1,PRKAA2,RARA,RBPJ,RELA,RLF,RXRB,SERTAD2,SHOX,TAF7L,TNKS2,TRIM16,TRIM32,VCP,ZBTB17,ZNF350,ZNF398,ZNF516 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 5.0e-07 | 7.2e-05 | 397 | 1721 | 35 | AKR1B1,ANG,AP3S1,ATP2B1,ATP6V1A,CA9,CACNB1,CD68,DDX17,FECH,GGT1,GSTP1,HTRA3,ING2,ME1,MGARP,NCOA3,OGT,OR56A1,PDE2A,PGF,PKM,POR,PRKAA2,PXN,RARA,RBPJ,RELA,RNF165,RRAGD,RXRB,TLR6,TRIM16,UBE2O,UPRT |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 5.0e-07 | 7.2e-05 | 397 | 987 | 25 | ADAM8,ALKBH5,ATP6V1A,BCAP31,BNIP3,BNIP3L,CNOT8,EGF,FEZ1,FZR1,GAPDH,HCAR2,IGF2BP1,IRGM,OGT,PFKFB4,PKD1,PRKAA2,PSMB4,RELA,RRAGD,SUFU,TMF1,TRIM32,VCP |
| GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 5.0e-07 | 7.5e-05 | 397 | 856 | 23 | ADPRHL2,ALKBH5,ASCC1,BACH1,CDKN2D,CNOT8,DYRK1A,EGLN3,FZR1,GGN,H4C8,ING2,MORF4L1,NDRG1,NFATC2,NHEJ1,PIAS4,POLG,POLI,POLN,SMYD2,TRIM32,VCP |
| GO_CHROMATIN_ORGANIZATION | 6.0e-07 | 8.0e-05 | 397 | 795 | 22 | CDC73,CHD5,H2AC13,H2BC15,H3C8,H4C8,ING2,KDM5C,LOXL2,MORF4L1,NCOA3,NPM2,OGT,PRKAA2,RELA,RLF,RSBN1,SAP30,SMYD2,TRIM16,YEATS2,ZNF274 |
| GO_REGULATION_OF_TRANSPORT | 6.0e-07 | 8.2e-05 | 397 | 1894 | 37 | ADAM8,ANG,ANO6,ATP2B1,BAIAP3,BCAP31,BNIP3L,CACNB1,CLIC2,EGF,FEZ1,GAPDH,GLRX,GPI,HCAR2,IL2RG,KCNAB1,KLF7,LIME1,MKLN1,NMU,OR56A1,PANX2,PRSS8,RAB20,RGS2,SGIP1,SH3GL1,SMAP1,SUFU,TCAF2,TLR6,TM9SF4,TMF1,TP53BP2,TRIM16,WLS |
| GO_REGULATION_OF_PROTEOLYSIS | 6.0e-07 | 8.4e-05 | 397 | 735 | 21 | ADAM8,AMBP,ASPH,BCAP31,CDKN2D,EFNA3,EGF,EGLN3,ENO1,F3,FAM162A,GAPDH,NOL3,OGT,PKD1,POR,SUFU,TMF1,TRIM32,UBE2O,VCP |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 7.0e-07 | 9.2e-05 | 397 | 289 | 13 | BCAP31,BNIP3,CDKN2D,ENO1,ERO1A,ING2,MLLT11,NOL3,P4HB,PDK1,PIAS4,TP53BP2,TRIM32 |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 7.0e-07 | 9.5e-05 | 397 | 1673 | 34 | ACADVL,ANG,BACH1,CBFA2T2,CDC73,CNOT8,ENO1,GAPDH,GSTP1,H3C8,H4C8,IGF2BP1,KDM5C,KLF7,LOXL2,MAGEA2B,MORF4L1,NFATC2,PDE2A,PIAS4,RARA,RBAK,RBPJ,RELA,RGS2,SAP30,SMYD2,SSX1,SUFU,YEATS2,ZBTB21,ZNF274,ZNF350,ZNF653 |
| GO_PROTEIN_ACETYLATION | 8.0e-07 | 1.0e-04 | 397 | 202 | 11 | CHD5,ESCO1,MAGEA2B,MORF4L1,NAA30,NCOA3,OGT,POR,PRKAA2,TRIM16,YEATS2 |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 8.0e-07 | 1.0e-04 | 397 | 1301 | 29 | ADAM8,AMBP,ANKZF1,AP2M1,BCAP31,BCKDHA,BNIP3,BNIP3L,EGF,FZR1,GGT1,IDS,JKAMP,MAGEA2B,MARCHF6,OGT,PDE2A,PKD1,PSMB4,RELA,RNF122,RNF165,SUFU,TMF1,TRIM32,UBE2O,UBR3,UBR4,VCP |
| GO_TRANSMEMBRANE_TRANSPORT | 8.0e-07 | 1.0e-04 | 397 | 1604 | 33 | ABCB6,ANO6,ASPH,ATP2B1,ATP6V1A,CACNB1,CLIC2,CNNM2,COX6B1,ERO1A,GLRX,KCNAB1,LIME1,MCUB,MFSD9,NIPAL3,NOL3,OR56A1,PANX2,PDE2A,PKD1,PRKAA2,PSMB4,RGS2,RHCE,SLC22A14,SLC25A36,SLC2A3,SLC35E1,SLC6A6,SLC6A8,TCAF2,VCP |
| GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS | 8.0e-07 | 1.0e-04 | 397 | 1016 | 25 | ADAMTS16,AKR1B1,ALDOA,ALKBH5,AMBP,ANG,ASZ1,BCAP31,CHD5,DPCD,DUSP13,EPN1,GGN,GGT1,ING2,ITGA5,NPM2,PGF,RARA,RGS2,SPAG4,TAF7L,TMF1,UPRT,ZP1 |
| GO_REPRODUCTION | 9.0e-07 | 1.1e-04 | 397 | 1457 | 31 | ADAM15,ADAMTS16,AKR1B1,ALDOA,ALKBH5,AMBP,ANG,ASZ1,BCAP31,CHD5,DPCD,DUSP13,EPN1,FZR1,GGN,GGT1,ING2,ITGA5,NPM2,PGF,PKD1,RARA,RBPJ,RGS2,RTF2,SPAG4,TAF7L,TMF1,TUBGCP2,UPRT,ZP1 |
| GO_RESPONSE_TO_OXIDATIVE_STRESS | 9.0e-07 | 1.1e-04 | 397 | 453 | 16 | ADPRHL2,ANKZF1,BNIP3,EGLN1,ERO1A,GSTP1,LDHA,NDUFA6,NOL3,P4HB,PDK1,PRDX1,PRKAA2,PXN,RELA,TLR6 |
| GO_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 1.1e-06 | 1.3e-04 | 397 | 351 | 14 | ADPRHL2,AKR1B1,ANKZF1,BNIP3,ERO1A,GSTP1,NOL3,P4HB,PDK1,PRDX1,PRKAA2,PXN,RELA,TLR6 |
| GO_PROTEIN_HYDROXYLATION | 1.2e-06 | 1.3e-04 | 397 | 24 | 5 | ASPH,EGLN1,EGLN3,P4HB,PLOD1 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 1.3e-06 | 1.5e-04 | 397 | 1410 | 30 | ADAM8,ALKBH5,AMBP,ANKZF1,AP2M1,BCAP31,BNIP3,BNIP3L,CNOT8,EGF,FZR1,IDS,IGF2BP1,JKAMP,MAGEA2B,MARCHF6,OGT,PKD1,PSMB4,RELA,RNASET2,RNF122,RNF165,SUFU,TMF1,TRIM32,UBE2O,UBR3,UBR4,VCP |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 1.3e-06 | 1.5e-04 | 397 | 1114 | 26 | CDC73,DCAF5,FBXO15,FZR1,H2BC15,HERC3,JOSD1,KCTD9,MAGEA2B,MARCHF6,OGT,PDZD4,PIAS4,PSMB4,RAB40C,RELA,RNF122,RNF165,TNKS2,TRIM32,UBE2O,UBR3,UBR4,VCP,VCPIP1,WSB1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 1.4e-06 | 1.5e-04 | 397 | 1724 | 34 | ADAM8,ANG,ASPH,AVPI1,BCAP31,CARD14,CASS4,DYRK1A,EFNA3,EGF,EGLN3,ENO1,F3,FAM162A,FZR1,IGFBP3,ING2,IRGM,ITGA5,MAGEA2B,MAP3K2,NENF,OGT,PGF,PIAS4,PKD1,PRKAA2,RASSF2,RELA,TEC,TLR6,TRIM32,VCP,VEGFD |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 1.4e-06 | 1.5e-04 | 397 | 526 | 17 | ATP2B1,CD68,CDKN2D,CHSY1,FADS1,GSTP1,LDHA,NENF,OGT,PKM,POR,PRKAA2,RARA,RELA,RRAGD,SGIP1,WDR45B |
| GO_SKELETAL_SYSTEM_DEVELOPMENT | 1.4e-06 | 1.5e-04 | 397 | 526 | 17 | ANO6,CHSY1,CSRNP1,HOXA13,LOXL2,PAPPA2,PKD1,POR,PRDX1,PRPSAP2,RARA,RASSF2,RELA,SHOX,SUFU,VKORC1,VWA1 |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 1.6e-06 | 1.7e-04 | 397 | 782 | 21 | ANKZF1,AP2M1,BCAP31,BNIP3,BNIP3L,EGF,FZR1,JKAMP,MAGEA2B,MARCHF6,OGT,PKD1,PSMB4,RNF122,SUFU,TMF1,TRIM32,UBE2O,UBR3,UBR4,VCP |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 1.6e-06 | 1.7e-04 | 397 | 984 | 24 | ADAM8,ANG,ANO6,ATP2B1,BAIAP3,BCAP31,EGF,FEZ1,GAPDH,GLRX,GPI,HCAR2,IL2RG,NMU,PANX2,PRSS8,SGIP1,SH3GL1,TCAF2,TM9SF4,TMF1,TP53BP2,TRIM16,WLS |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 1.7e-06 | 1.7e-04 | 397 | 1427 | 30 | AMBP,ARHGEF7,CBFA2T2,CDKN2D,CLIC2,DYRK1A,EGF,ENO1,EPN1,GSTP1,HTRA3,IGFBP3,ING2,KLF7,NLRC3,NOL3,OR56A1,PDE2A,PIAS4,PRKAA2,PSMB4,RASSF2,RELA,RGS2,SAG,SNX13,SUFU,TLR6,TRIM32,ZNF653 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 1.8e-06 | 1.8e-04 | 397 | 1988 | 37 | AKNAD1,BACH1,CDC73,CSRNP1,DDX17,DDX41,DYRK1A,EGF,ENO1,ING2,KLF7,MAP3K2,MLLT11,NCOA3,NFATC2,NPM2,OGT,PKD1,POR,PPP1R3E,RARA,RBPJ,RELA,RLF,RXRB,SERTAD2,SHOX,TAF7L,TLR6,TNKS2,TRIM16,TRIM32,VCP,ZBTB17,ZNF350,ZNF398,ZNF516 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1.8e-06 | 1.8e-04 | 397 | 1823 | 35 | ADAM8,AK4,AMBP,ANG,AVPI1,CARD14,CASS4,CDKN2D,EGF,ENO1,FARP1,FKBP15,GSTP1,IGFBP3,IRGM,ITGA5,LIME1,MAP3K2,NENF,OGT,PDK1,PFKFB4,PGF,PGK1,PKD1,PPME1,PRDX1,PRKAA2,RASSF2,RGS2,SAG,TEC,TLR6,VCP,VEGFD |
| GO_RESPONSE_TO_HORMONE | 1.9e-06 | 1.9e-04 | 397 | 994 | 24 | AKR1B1,ANG,AP3S1,ATP2B1,ATP6V1A,CA9,DDX17,FECH,GGT1,GSTP1,ME1,MGARP,NCOA3,OGT,PGF,PKM,POR,PRKAA2,PXN,RARA,RELA,RXRB,TRIM16,UPRT |
| GO_APOPTOTIC_SIGNALING_PATHWAY | 2.1e-06 | 2.1e-04 | 397 | 603 | 18 | BCAP31,BNIP3,BNIP3L,CDKN2D,ENO1,ERO1A,FAM162A,GSTP1,ING2,MKNK2,MLLT11,NOL3,P4HB,PDK1,PIAS4,RELA,TP53BP2,TRIM32 |
| GO_POSITIVE_REGULATION_OF_CELL_DEATH | 2.5e-06 | 2.4e-04 | 397 | 737 | 20 | ADAM8,ANO6,ARHGEF7,BCAP31,BNIP3,BNIP3L,EGLN3,F3,FAM162A,GAPDH,HCAR2,IGFBP3,LDHA,MLLT11,PIAS4,RASSF2,RNF122,TLR6,TP53BP2,VCP |
| GO_ELECTRON_TRANSPORT_CHAIN | 2.6e-06 | 2.5e-04 | 397 | 185 | 10 | AKR1B1,ASPH,COX6B1,ETFA,GLRX,LOXL2,ME1,NDUFA6,NDUFA8,POR |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 3.1e-06 | 2.9e-04 | 397 | 1470 | 30 | BACH1,CBFA2T2,CDC73,DYRK1A,ENO1,H3C8,H4C8,IGF2BP1,KDM5C,KLF7,LOXL2,MAGEA2B,MORF4L1,NFATC2,PDE2A,PIAS4,RARA,RBAK,RBPJ,RELA,SAP30,SMYD2,SSX1,SUFU,TNKS2,YEATS2,ZBTB21,ZNF274,ZNF350,ZNF653 |
| GO_SMALL_MOLECULE_CATABOLIC_PROCESS | 3.1e-06 | 2.9e-04 | 397 | 440 | 15 | ACADVL,AKR1B10,ALDOA,BCKDHA,CYP4F11,ENO1,ENO2,ENTPD1,ETFA,GAPDH,GPI,PGD,PGK1,PKM,TPI1 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 3.5e-06 | 3.2e-04 | 397 | 1880 | 35 | ADAM8,AMBP,ANG,AVPI1,CARD14,CASS4,CDKN2D,DYRK1A,EGF,FZR1,GSTP1,IGFBP3,ING2,IRGM,ITGA5,LIME1,MAGEA2B,MAP3K2,NENF,OGT,PGF,PIAS4,PKD1,PPME1,PRDX1,PRKAA2,RASSF2,RELA,RGS2,SAG,TEC,TLR6,VCP,VEGFD,ZNF274 |
| GO_CATION_TRANSPORT | 3.7e-06 | 3.4e-04 | 397 | 1180 | 26 | ABCB6,ANO6,ATP2B1,ATP6V1A,CACNB1,CLIC2,CNNM2,COX6B1,EGF,ERO1A,GLRX,KCNAB1,LIME1,MCUB,NIPAL3,NOL3,OR56A1,PANX2,PDE2A,PKD1,PRSS8,RGS2,RHCE,SLC22A14,SLC48A1,SLC6A8 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 4.2e-06 | 3.7e-04 | 397 | 831 | 21 | ADAM8,ALKBH5,ATP6V1A,BCAP31,BNIP3,BNIP3L,CNOT8,EGF,FEZ1,GAPDH,IGF2BP1,IRGM,OGT,PFKFB4,PKD1,PRKAA2,PSMB4,RRAGD,SUFU,TMF1,VCP |
| GO_PROTEIN_ACYLATION | 5.2e-06 | 4.6e-04 | 397 | 246 | 11 | CHD5,ESCO1,MAGEA2B,MORF4L1,NAA30,NCOA3,OGT,POR,PRKAA2,TRIM16,YEATS2 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 5.3e-06 | 4.7e-04 | 397 | 1280 | 27 | BACH1,CBFA2T2,CDC73,ENO1,H3C8,H4C8,KDM5C,KLF7,LOXL2,MAGEA2B,MORF4L1,NFATC2,PDE2A,PIAS4,RARA,RBAK,RBPJ,RELA,SAP30,SMYD2,SSX1,SUFU,YEATS2,ZBTB21,ZNF274,ZNF350,ZNF653 |
Num: 13 (Pathways: 8 DK: 2)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (2) | BCKDK, TBCK |
| Light Kinase (1) | DDR1 |
| Non-kinase Count | 118 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_INTRACELLULAR_TRANSPORT | 0e+00 | 0.0e+00 | 121 | 1741 | 26 | ACTR10,ARFIP2,COX5B,DCTN3,DHRS4,DNAJC30,HSD17B4,HTRA2,IFI27,IFT122,KDELR1,MYO7A,NDUFA13,PEX19,PREPL,RAB13,ROMO1,RPS26,SIL1,SNF8,SNRPD2,TBCK,TMCC1,TRAM1,TRAPPC3,ZPR1 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0e+00 | 1.1e-05 | 121 | 1151 | 17 | ARFIP2,DHRS4,HSD17B4,HTRA2,IFI27,IFT122,MYO7A,NDUFA13,PEX19,RAB13,ROMO1,RPS26,SIL1,SNF8,TBCK,TRAM1,ZPR1 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0e+00 | 2.0e-05 | 121 | 1930 | 21 | ARFIP2,BBS1,DHRS4,HSD17B4,HTRA2,IFI27,IFT122,KDELR1,KPTN,MYO7A,NDUFA13,PEX19,PREPL,RAB13,ROMO1,RPS26,SIL1,SNF8,TBCK,TRAM1,ZPR1 |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 1e-07 | 1.5e-04 | 121 | 944 | 14 | BBS1,DHRS4,HSD17B4,HTRA2,IFT122,KDELR1,KPTN,NDUFA13,PEX19,ROMO1,RPS26,SNF8,TRAM1,ZPR1 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 1e-07 | 2.1e-04 | 121 | 564 | 11 | DHRS4,HSD17B4,HTRA2,IFT122,NDUFA13,PEX19,ROMO1,RPS26,SNF8,TRAM1,ZPR1 |
| GO_OXIDATION_REDUCTION_PROCESS | 2e-07 | 2.1e-04 | 121 | 1005 | 14 | ACADM,ASPHD1,CDO1,COX5B,DHRS4,DHRS4L2,GMPR2,HSD17B4,NDUFA11,NDUFA13,NDUFAF1,NDUFB8,NQO2,PRDX2 |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 3e-07 | 2.9e-04 | 121 | 1962 | 19 | ACADM,ACOT13,APOBEC3F,BCKDK,CDO1,CES2,COMT,COX5B,DHRS4,DNAJC30,FGF1,GMPR2,HSD17B4,ITIH4,MAN2C1,NUDT9,PLA2G4B,PSME1,SLC35B3 |
| GO_NADH_DEHYDROGENASE_COMPLEX_ASSEMBLY | 5e-07 | 4.9e-04 | 121 | 64 | 5 | NDUFA11,NDUFA13,NDUFAF1,NDUFAF3,NDUFB8 |
Num: 15 (Pathways: 116 DK: 2)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (2) | PI4KA, RNASEL |
| Light Kinase (16) | BMPR2, CDK5, EPHA10, EPHB4, FPGT-TNNI3K, JAK3, MAP2K4, PDGFRB, PDK2, PIK3C2A, PRKD3, PTK7, ROCK1, SPEG, SRC, TRIM24 |
| Non-kinase Count | 435 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 453 | 1335 | 47 | APC,ARHGAP17,ARHGEF11,BCL2,BICD2,BRWD3,CARMIL1,CCDC120,CCDC88C,CCN2,CD2AP,CDK5,CDK5R1,CEP131,DCTN1,DLG1,DNAL1,ELN,EPB41L1,GCC2,KATNAL1,KIF3B,KRAS,MAP7D1,MID1,MYH9,NF2,NISCH,PACSIN2,PACSIN3,PDGFRB,PHLDB2,PLD2,POF1B,PTK7,RHOBTB3,ROCK1,SHANK3,SIPA1,SPAST,SRC,SYNPO2L,TBCD,TERF1,TMOD4,TPR,USP33 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 0.0e+00 | 453 | 1267 | 44 | APC,ARHGAP17,BCL2,BECN1,BICD2,CARMIL1,CCN2,CD2AP,CDK5,CDK5R1,CEP131,CTR9,DCTN1,DLG1,ELN,GBA,GLYR1,IGF1,LAPTM4B,MID1,MORC2,NF2,PDGFRB,PHF8,PHLDB2,PPP1R13B,PTPRS,RHOBTB3,RNF20,ROCK1,RTF1,SHANK3,SPAST,SRC,SYNPO2L,TBCD,TERF1,TMOD4,TPR,VAMP1,VPS13D,XRN1,YWHAB,ZMPSTE24 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 0.0e+00 | 453 | 1930 | 54 | ACAA1,AGER,AKAP5,APC,BCL2,BECN1,BICD2,CAT,CD2AP,CDK5,CDK5R1,CEP131,CLSTN1,CNPY4,DHX38,DLG1,DYNLL2,FYTTD1,GCC2,GNPTAB,GPC1,HSPB1,IPO13,KIF3B,KPNA6,MAPK8IP3,MBTPS1,MID1,MYO6,NF2,NPAP1,PACSIN2,PPP1R13B,RAB40AL,RAB40B,RANBP17,RANBP2,ROCK1,RRAGB,SHANK3,SRC,SRSF5,STAC3,SYTL4,TBC1D13,TERF1,TPR,TSPAN17,USP46,VPS13D,VPS36,YWHAB,ZDHHC3,ZNF385A |
| GO_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 453 | 1864 | 52 | ANAPC2,APC,BCL2,BECN1,BIRC6,C11orf80,CASP2,CCN2,CCNL2,CCNQ,CD2AP,CDK5,CDK5R1,CEP131,CEP164,DCTN1,DLG1,ERCC3,FAM32A,FOXE3,GIGYF2,GIT1,HMGN5,ID3,IGF1,INCA1,KIF3B,MED25,MGA,MYH9,NANOS3,NF2,NPAT,PDGFRB,PHF8,PPP1R12B,PPP1R13B,RBBP7,ROCK1,RRAGB,SIPA1,SPAST,SRC,SRSF5,TBCD,TERF1,TPR,USP28,USP33,UTP14C,ZMPSTE24,ZNF385A |
| GO_REGULATION_OF_CELL_CYCLE | 0.0e+00 | 0.0e+00 | 453 | 1224 | 41 | ANAPC2,APC,BCL2,BECN1,BIRC6,CASP2,CCN2,CCNL2,CCNQ,CDK5,CDK5R1,CEP131,CEP164,DCTN1,DLG1,ERCC3,FOXE3,GIGYF2,GIT1,HMGN5,ID3,IGF1,INCA1,KIF3B,MED25,MGA,NANOS3,NF2,PDGFRB,PPP1R13B,RBBP7,RRAGB,SIPA1,SPAST,SRC,SRSF5,TERF1,TPR,USP28,ZMPSTE24,ZNF385A |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 0.0e+00 | 453 | 1698 | 48 | AGER,ALAD,APC,ATP6V1B1,BCL2,BECN1,CAT,CCN2,CDK5,CDK5R1,CTR9,CTSV,DUOX1,DYNAP,EPM2AIP1,ERCC6L2,FDX1,GABPA,GBA,GGH,GLB1,GNA11,HRH4,ID3,IGF1,JAK3,MAP2K4,NCSTN,PDE8A,PDGFRB,PDK2,PIK3C2A,POLB,PTK7,ROCK1,RRAGB,SIPA1,SMARCD1,SRC,SRD5A1,SRSF5,SULT1A3,TRIM24,TRPV1,TSHR,USF1,USP46,XRN1 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 453 | 1470 | 44 | AEBP2,AHRR,BMPR2,BPTF,CBX1,CC2D1A,CDK5,CDK5R1,CTR9,DDX5,DLG1,GABPA,HDAC10,ID3,LDB1,MED25,MGA,MORC2,NPAT,NRDE2,PARP15,PHF10,PHF8,PTBP3,RBBP7,RCOR1,RD3,RNF20,RTF1,S100A1,SMARCC2,SPEN,SRC,TAF15,TERF1,TPR,TRIM24,TRPV1,UBP1,XRN1,YWHAB,ZMPSTE24,ZNF224,ZNF8 |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 453 | 1741 | 48 | ACAA1,ACACB,AKAP5,BECN1,BICD2,CAT,CCDC88C,CDK5,CDK5R1,CEP131,DCTN1,DHX38,DOP1A,DYNLL2,FYTTD1,GCC2,GNPTAB,HSPB1,IPO13,KIF1C,KIF3B,KPNA6,LAPTM4B,MAPK8IP3,MBTPS1,MYO1D,MYO6,NPAP1,NRDE2,PHETA2,RAB40AL,RAB40B,RANBP17,RANBP2,RELCH,RHOBTB3,RSRC1,SPAST,SRC,SRSF5,SYTL4,TBC1D13,TPR,VPS13D,VPS36,YWHAB,ZDHHC3,ZMPSTE24 |
| GO_MICROTUBULE_BASED_PROCESS | 0.0e+00 | 0.0e+00 | 453 | 752 | 30 | APC,BICD2,CABYR,CCDC120,CCDC88C,CDK5,CDK5R1,CEP131,CFAP54,DCTN1,DLG1,DNAL1,DYNLL2,GCC2,HSPB1,KATNAL1,KIF1C,KIF3B,KIF7,MAP7D1,MAPK8IP3,MID1,MYH9,PHLDB2,RSPH6A,SPAST,TBCD,TERF1,TPR,USP33 |
| GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 0.0e+00 | 0.0e+00 | 453 | 1721 | 47 | AGER,ALAD,APC,ATP6V1B1,BCL2,BECN1,BMPR2,CAT,CCN1,CCN2,CDK5,CDK5R1,CHRDL1,CTSV,DDX5,EPM2AIP1,FDX1,GABPA,GBA,GGH,GLB1,GNA11,GPC1,HRH4,IGF1,JAK3,KIDINS220,KRAS,NCSTN,PDE8A,PDGFRB,PDK2,PIK3C2A,RBBP7,ROCK1,RRAGB,SRC,SRD5A1,SRSF5,SULT1A3,TPR,TRPV1,TSHR,USF1,XRN1,ZMPSTE24,ZNF8 |
| GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 0.0e+00 | 453 | 534 | 25 | APC,ARHGAP17,BICD2,CARMIL1,CCN2,CD2AP,CDK5,CDK5R1,CEP131,DCTN1,DLG1,ELN,MID1,NF2,PDGFRB,PHLDB2,RHOBTB3,ROCK1,SHANK3,SPAST,SYNPO2L,TBCD,TERF1,TMOD4,TPR |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 0.0e+00 | 0.0e+00 | 453 | 1220 | 38 | ANAPC2,APC,BCL2,BECN1,BMPR2,CARMIL1,CCN2,CDK5,CDK5R1,CLSTN1,CRABP2,CTR9,DCTN1,DLG1,ERCC3,GBA,GLYR1,IGF1,KIDINS220,MED25,MORC2,NF2,PDGFRB,PHLDB2,PPP1R13B,PTK7,RNF20,ROCK1,RTF1,SHANK3,SLITRK5,SPAST,SRC,SYNPO2L,TERF1,TPR,VPS13D,YWHAB |
| GO_NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 453 | 1673 | 45 | AEBP2,AHRR,BMPR2,BPTF,CBX1,CC2D1A,CDK5,CDK5R1,CTR9,DDX5,DLG1,GABPA,GIGYF2,HDAC10,ID3,JAK3,LDB1,MED25,MGA,MORC2,NANOS3,NPAT,NRDE2,PARP15,PHF10,PHF8,RBBP7,RCOR1,RD3,ROCK1,RTF1,S100A1,SMARCC2,SPEN,SRC,TERF1,TNRC6A,TPR,TRIM24,TRPV1,UBP1,XRN1,YWHAB,ZNF224,ZNF8 |
| GO_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 1.0e-07 | 453 | 669 | 27 | APC,ARHGAP17,BCL2,CARMIL1,CCDC88C,CCN2,CD2AP,CDK5R1,COL11A1,DCTN1,DLG1,ELN,KATNAL1,MID1,NF2,PDGFRB,PHLDB2,POF1B,RHOBTB3,ROCK1,SHANK3,SPAST,SRC,SYNPO2L,TBCD,TERF1,TMOD4 |
| GO_SYNAPTIC_SIGNALING | 0.0e+00 | 1.0e-07 | 453 | 733 | 28 | AGER,AKAP5,ANAPC2,CDK5,CDK5R1,CLSTN1,DLG1,FBXL20,GABRE,GIT1,GNA11,HRH4,KCNIP2,KRAS,NAAA,NCSTN,NISCH,NRGN,PACSIN2,PTPRS,SHANK3,SHISA9,SLITRK5,SRC,STAC3,TRPV1,USP46,VAMP1 |
| GO_CELL_CELL_SIGNALING | 0.0e+00 | 2.0e-07 | 453 | 1665 | 44 | AGER,AKAP5,ANAPC2,APC,CCDC88C,CDK5,CDK5R1,CLSTN1,CTR9,DLG1,FBXL20,GABRE,GAL3ST4,GIT1,GNA11,HRH4,KCNIP2,KRAS,LDB1,MCU,MED12,NAAA,NCSTN,NISCH,NRGN,PACSIN2,PLCB3,PTK7,PTPRS,RTF1,SHANK3,SHISA9,SLITRK5,SRC,STAC3,SYTL4,TMEM64,TNRC6A,TRPV1,TSHR,USP34,USP46,VAMP1,WNT2B |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 0.0e+00 | 3.0e-07 | 453 | 766 | 28 | ARHGAP17,ARHGEF11,BCL2,CARMIL1,CCN2,CD2AP,CDK5,CDK5R1,DLG1,ELN,EPB41L1,KCNJ8,KRAS,MYH9,MYO6,NF2,NISCH,PACSIN2,PDGFRB,PHLDB2,POF1B,PTK7,RHOBTB3,ROCK1,SHANK3,SRC,SYNPO2L,TMOD4 |
| GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 0.0e+00 | 4.0e-07 | 453 | 624 | 25 | BCL2,BECN1,CARMIL1,CCN2,CDK5,CDK5R1,CTR9,DCTN1,DLG1,GBA,GLYR1,IGF1,MORC2,NF2,PDGFRB,PPP1R13B,RNF20,RTF1,SPAST,SRC,SYNPO2L,TERF1,TPR,VPS13D,YWHAB |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 0.0e+00 | 4.0e-07 | 453 | 944 | 31 | ACAA1,APC,BCL2,BECN1,BICD2,CAT,CD2AP,CDK5,CEP131,DLG1,GCC2,GNPTAB,IPO13,KPNA6,MBTPS1,MID1,NF2,NPAP1,PACSIN2,PPP1R13B,RANBP17,RANBP2,SRC,TERF1,TPR,TSPAN17,USP46,VPS13D,VPS36,YWHAB,ZDHHC3 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 4.0e-07 | 453 | 1863 | 46 | AGER,AKAP5,ARHGAP17,ARHGEF11,ARHGEF40,BCL2,BECN1,CAT,CC2D1A,CCN1,CCN2,CD2AP,CDK5,CDK5R1,DDX5,DLG1,EMC10,GARNL3,GBA,GPS1,HRH4,HSPB1,IGF1,KIDINS220,KRAS,LRRC19,MAP2K4,MAPK8IP3,MID1,NF2,PDE8A,PDGFRB,PDK2,PPP1R13B,RALGPS2,RBBP7,ROCK1,RRAGB,RRM2B,SIPA1,SRC,SYNPO2L,TAF15,TRIM24,ZMPSTE24,ZNF385A |
| GO_REGULATION_OF_CELL_CYCLE_PROCESS | 0.0e+00 | 5.0e-07 | 453 | 790 | 28 | ANAPC2,APC,BCL2,BECN1,BIRC6,CASP2,CCN2,CDK5,CDK5R1,CEP131,CEP164,DCTN1,ERCC3,FOXE3,GIGYF2,GIT1,HMGN5,IGF1,KIF3B,MED25,MGA,PDGFRB,RBBP7,SPAST,TERF1,TPR,ZMPSTE24,ZNF385A |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 6.0e-07 | 453 | 1962 | 47 | ABCC5,ACAA1,ACACB,ACSS3,ATP6V1B1,CARMIL1,CAT,CRABP2,D2HGDH,DLD,DLG1,EPM2AIP1,FASN,FDX1,GBA,GGH,GLB1,GNMT,GSTM4,HIBCH,HTD2,IDO2,IGF1,LCAT,MBTPS1,MORC2,NAAA,NISCH,NMNAT3,PANK2,PCYOX1,PDE8A,PDK2,PLCB3,PTH1R,RANBP2,RD3,RDH13,RRM2B,SRC,SRD5A1,SUCLA2,SULT1A3,TPR,UGT2A1,USF1,ZMPSTE24 |
| GO_EMBRYO_DEVELOPMENT | 0.0e+00 | 7.0e-07 | 453 | 1029 | 32 | ATP6V1B1,BIRC6,BMPR2,BPTF,CCN1,CDK5R1,COL11A1,CRABP2,CTR9,DLD,DLG1,ECE1,ERCC3,GABPA,HOXB6,ID3,IGF1,KIDINS220,LDB1,MED12,MYH9,NF2,NPAT,OTX1,PHLDB2,POLB,PPP2R3A,PTH1R,PTK7,ROCK1,RTF1,WNT2B |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 0.0e+00 | 7.0e-07 | 453 | 1208 | 35 | AGER,APC,ATP6V1B1,BECN1,CDK5,CDK5R1,CTR9,DYNAP,ERCC6L2,FDX1,GABPA,GNA11,HRH4,ID3,IGF1,JAK3,MAP2K4,NCSTN,PDE8A,PDK2,PIK3C2A,PTK7,ROCK1,RRAGB,SIPA1,SMARCD1,SRC,SRD5A1,SRSF5,SULT1A3,TRIM24,TRPV1,TSHR,USF1,XRN1 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 0.0e+00 | 9.0e-07 | 453 | 1280 | 36 | AEBP2,AHRR,BPTF,CBX1,CC2D1A,CDK5,CDK5R1,CTR9,DDX5,DLG1,GABPA,HDAC10,ID3,LDB1,MED25,MGA,MORC2,NPAT,NRDE2,PARP15,PHF10,PHF8,RBBP7,RCOR1,RTF1,S100A1,SMARCC2,SPEN,SRC,TPR,TRIM24,TRPV1,UBP1,YWHAB,ZNF224,ZNF8 |
| GO_LIPID_METABOLIC_PROCESS | 0.0e+00 | 9.0e-07 | 453 | 1405 | 38 | ABHD12,ACAA1,ACACB,ATP6V1B1,CAT,CCN1,CRABP2,DLD,FASN,FDX1,GAL3ST4,GBA,GLB1,GPC1,GSTM4,HTD2,LCAT,MBTPS1,MORC2,NAAA,PANK2,PDGFRB,PDK2,PI4KA,PIK3C2A,PISD,PITPNA,PLBD2,PLCB3,PLD2,PRKD3,PTDSS2,RDH13,SRC,SRD5A1,SULT1A3,TRPV1,ZMPSTE24 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 9.0e-07 | 453 | 1994 | 47 | AGER,APC,BCL2,BIRC6,BMPR2,CCDC88C,CCN1,CCN2,CCNL2,CCNQ,CDK5,CDK5R1,DLG1,DYNAP,EMC10,EPHA10,EPHB4,ERCC3,GBA,GPS1,HRH4,HSPB1,IGF1,INCA1,JAK3,KIDINS220,KRAS,MAP2K4,MAPK8IP3,MID1,NF2,PDE8A,PDGFRB,PDK2,PHKA2,PRKD3,PTK7,RNASEL,ROCK1,RSRC1,SHANK3,SPEG,SRC,SULT1A3,TRIM24,YWHAB,ZMPSTE24 |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 0.0e+00 | 9.0e-07 | 453 | 1410 | 38 | ABHD12,ALAD,ANAPC2,APC,BECN1,BIRC6,CD2AP,CDK5,CTSV,DDX5,DIS3L,DROSHA,FBXL20,GBA,GIGYF2,GLB1,GPC1,HSPB1,KLHL25,LAPTM4B,NANOS3,NRDE2,PACSIN3,PCYOX1,PHKA2,RNF20,ROCK1,TAF15,TNRC6A,TRIM24,USP28,USP33,USP34,USP46,VPS36,XRN1,YWHAB,ZMPSTE24 |
| GO_CELLULAR_COMPONENT_MORPHOGENESIS | 0.0e+00 | 1.9e-06 | 453 | 1141 | 33 | ANAPC2,BCL2,BMPR2,BRWD3,CARMIL1,CDK5,CDK5R1,CRABP2,DLG1,EPHA10,GPC1,KIDINS220,MYH9,PACSIN2,PANK2,PDGFRB,PHLDB2,PITPNA,POF1B,PTPRS,RHOBTB3,ROCK1,SHANK3,SLITRK5,SPAST,SRC,SYNPO2L,TBCD,TMOD4,USP33,ZMPSTE24,ZMYM2,ZNF385A |
| GO_CELL_CYCLE_PROCESS | 0.0e+00 | 2.3e-06 | 453 | 1399 | 37 | ANAPC2,APC,BCL2,BECN1,BIRC6,C11orf80,CASP2,CCN2,CDK5,CDK5R1,CEP131,CEP164,DCTN1,DLG1,ERCC3,FOXE3,GIGYF2,GIT1,HMGN5,IGF1,KIF3B,MED25,MGA,MYH9,NPAT,PDGFRB,PHF8,PPP1R12B,RBBP7,ROCK1,RRAGB,SPAST,TERF1,TPR,USP33,ZMPSTE24,ZNF385A |
| GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 0.0e+00 | 2.6e-06 | 453 | 553 | 22 | APC,BICD2,CCDC120,CCDC88C,CDK5,CDK5R1,CEP131,DCTN1,DLG1,DNAL1,GCC2,KATNAL1,KIF3B,MAP7D1,MID1,MYH9,PHLDB2,SPAST,TBCD,TERF1,TPR,USP33 |
| GO_CELL_PROJECTION_ORGANIZATION | 0.0e+00 | 2.9e-06 | 453 | 1545 | 39 | AGER,ANAPC2,APC,BCL2,BMPR2,CARMIL1,CD2AP,CDK5,CDK5R1,CEP131,CEP162,CEP164,CFAP54,CRABP2,DCTN1,DNAL1,DYNLL2,DZIP1L,EPHA10,FAM161A,GPC1,GPRIN1,KIDINS220,KIF3B,MAPK8IP3,MYH9,PACSIN2,PITPNA,PTK7,PTPRS,RHOBTB3,ROCK1,RSPH6A,SHANK3,SLITRK5,SPAST,SRC,TTC36,USP33 |
| GO_REGULATION_OF_CELL_DEATH | 0.0e+00 | 3.1e-06 | 453 | 1748 | 42 | APC,ARHGEF11,BCL2,BECN1,BIRC6,CASP2,CAT,CCN1,CCN2,CDK5,CDK5R1,DDX42,DYNAP,ERCC3,FOXE3,GBA,HMGN5,HSPB1,ID3,IGF1,INCA1,JAK3,KRAS,LRPAP1,MAP2K4,NAA16,NANOS3,NCSTN,NF2,PDE8A,PDGFRB,PPP1R13B,ROCK1,RRM2B,SRC,SULT1A3,TERF1,TRIM24,TRPV1,YWHAB,ZNF385A,ZNF420 |
| GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 0.0e+00 | 3.5e-06 | 453 | 335 | 17 | BCL2,BECN1,BMPR2,CASP2,CTSV,GBA,MAP2K4,PDK2,RRAGB,SIPA1,SRD5A1,TNRC6A,TRIM24,TRPV1,USF1,USP33,WNT2B |
| GO_CELLULAR_LIPID_METABOLIC_PROCESS | 0.0e+00 | 3.8e-06 | 453 | 1064 | 31 | ABHD12,ACAA1,ACACB,ATP6V1B1,CAT,CCN1,CRABP2,DLD,FASN,GAL3ST4,GBA,GLB1,GPC1,GSTM4,HTD2,LCAT,MORC2,NAAA,PANK2,PDGFRB,PDK2,PI4KA,PIK3C2A,PISD,PLD2,PRKD3,PTDSS2,RDH13,SRC,SRD5A1,ZMPSTE24 |
| GO_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 4.6e-06 | 453 | 1135 | 32 | AGER,ALAD,APC,ATP6V1B1,CAT,CCN2,CDK5,CDK5R1,DUOX1,EPM2AIP1,FDX1,GABPA,GGH,GNA11,HRH4,IGF1,JAK3,NCSTN,PDK2,PIK3C2A,RANBP2,ROCK1,RRAGB,RRM2B,SRC,SRD5A1,SRSF5,SULT1A3,TRPV1,TSHR,USF1,XRN1 |
| GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 0.0e+00 | 5.1e-06 | 453 | 264 | 15 | BCL2,BECN1,BMPR2,CTSV,GBA,PDK2,RRAGB,SIPA1,SRD5A1,TNRC6A,TRIM24,TRPV1,USF1,USP33,WNT2B |
| GO_RESPONSE_TO_WOUNDING | 0.0e+00 | 5.4e-06 | 453 | 687 | 24 | AGER,BCL2,CARMIL1,CCN1,CCN2,CDK5,DUOX1,GNA11,HSPB1,ID3,IGF1,MAP2K4,MAPK8IP3,MYH9,PDGFRB,PHLDB2,PTGFRN,PTK7,PTPRS,RCOR1,SRC,SYTL4,TMIGD3,USF1 |
| GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 0.0e+00 | 5.6e-06 | 453 | 267 | 15 | BCL2,CASP2,CDK5,CDK5R1,DDX5,MYO6,PDK2,PPP1R13B,RBBP7,RRM2B,TAF15,TRIM24,USP28,ZMPSTE24,ZNF385A |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 0.0e+00 | 5.6e-06 | 453 | 1151 | 32 | ACAA1,AKAP5,BECN1,CAT,CDK5,CDK5R1,CEP131,DHX38,DYNLL2,FYTTD1,GCC2,GNPTAB,HSPB1,IPO13,KIF3B,KPNA6,MAPK8IP3,MBTPS1,MYO6,NPAP1,RAB40AL,RAB40B,RANBP17,RANBP2,SRSF5,SYTL4,TBC1D13,TPR,VPS13D,VPS36,YWHAB,ZDHHC3 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 5.6e-06 | 453 | 1870 | 43 | AHRR,ARHGEF11,BICRA,BMPR2,BPTF,CCN1,CTR9,DDX5,ERCC3,FAM168A,GABPA,GIGYF2,GLYR1,HDAC10,HMGN5,IGF1,KPNA6,LDB1,MED12,MED25,MGA,MYO6,NAA16,NANOS3,NPAT,OTX1,PDGFRB,PHF10,PHF8,POU2F2,RNASEL,RNF20,ROCK1,RTF1,SMARCC2,SMARCD1,SRC,SRSF5,TAF15,TFAP2E,TNRC6A,TRIM24,USF1 |
| GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 0.0e+00 | 5.6e-06 | 453 | 351 | 17 | APC,CARMIL1,CCN2,CDK5R1,DCTN1,DLG1,ELN,MID1,NF2,PHLDB2,ROCK1,SHANK3,SPAST,SYNPO2L,TBCD,TERF1,TMOD4 |
| GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 0.0e+00 | 8.5e-06 | 453 | 709 | 24 | AGER,APC,ATP6V1B1,CDK5,CDK5R1,FDX1,GABPA,GNA11,HRH4,IGF1,JAK3,NCSTN,PDK2,PIK3C2A,ROCK1,RRAGB,SRC,SRD5A1,SRSF5,SULT1A3,TRPV1,TSHR,USF1,XRN1 |
| GO_RESPONSE_TO_HORMONE | 0.0e+00 | 8.5e-06 | 453 | 994 | 29 | ALAD,APC,ATP6V1B1,BCL2,CAT,CCN2,CDK5R1,CTSV,DDX5,EPM2AIP1,GBA,GGH,GLB1,GNA11,HRH4,JAK3,KRAS,PDGFRB,PDK2,PIK3C2A,RBBP7,ROCK1,SRC,SRD5A1,SRSF5,TRPV1,TSHR,USF1,XRN1 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 1.0e-07 | 1.0e-05 | 453 | 1710 | 40 | AHRR,ARHGEF11,BICRA,BMPR2,BPTF,CCN1,CTR9,DDX5,ERCC3,GABPA,GIGYF2,GLYR1,HMGN5,IGF1,KPNA6,LDB1,MED12,MED25,MGA,MYO6,NAA16,NANOS3,NPAT,OTX1,PHF10,PHF8,POU2F2,RNASEL,RNF20,ROCK1,RTF1,SMARCC2,SMARCD1,SRC,SRSF5,TAF15,TFAP2E,TNRC6A,TRIM24,USF1 |
| GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 1.0e-07 | 1.2e-05 | 453 | 1454 | 36 | AGER,APC,ATP6V1B1,BECN1,BMPR2,CCN1,CCN2,CDK5,CDK5R1,CHRDL1,DDX5,FDX1,GABPA,GNA11,GPC1,HRH4,IGF1,JAK3,KIDINS220,NCSTN,PDE8A,PDGFRB,PDK2,PIK3C2A,ROCK1,RRAGB,SRC,SRD5A1,SRSF5,SULT1A3,TRPV1,TSHR,USF1,XRN1,ZMPSTE24,ZNF8 |
| GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 1.0e-07 | 1.8e-05 | 453 | 973 | 28 | ACACB,ALAD,BCL2,BECN1,CAT,CCN2,CDK5,CTSV,DDX5,DUOX1,DYNAP,FDX1,GABPA,GBA,GLB1,GNA11,HRH4,ID3,KRAS,NCSTN,PDGFRB,RBBP7,SRC,SRD5A1,SULT1A3,TRIM24,TRPV1,XRN1 |
| GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 1.0e-07 | 2.0e-05 | 453 | 387 | 17 | ARHGAP17,CARMIL1,CCN2,CD2AP,CDK5,CDK5R1,DLG1,ELN,MYH9,NF2,PDGFRB,PHLDB2,RHOBTB3,ROCK1,SHANK3,SYNPO2L,TMOD4 |
| GO_NEUROGENESIS | 1.0e-07 | 2.1e-05 | 453 | 1625 | 38 | ADGRG6,AGER,ANAPC2,BCL2,BECN1,BMPR2,CDK5,CDK5R1,CRABP2,EPHA10,ERCC3,GIGYF2,GPC1,GPRIN1,HDAC10,ID3,KCNIP2,KIDINS220,KRAS,LDB1,MAPK8IP3,MED12,NCSTN,NF2,PITPNA,PTK7,PTPRS,RDH13,RHOBTB3,ROCK1,SHANK3,SLITRK5,SPAST,SPEN,SRC,TBCD,USP33,WNT2B |
| GO_REGULATION_OF_CATABOLIC_PROCESS | 2.0e-07 | 2.3e-05 | 453 | 987 | 28 | ACACB,ALAD,APC,ATP6V1B1,BCL2,BECN1,CDK5,CDK5R1,FBXL20,GBA,GIGYF2,HSPB1,IGF1,LAPTM4B,NANOS3,NRDE2,PACSIN3,RANBP2,ROCK1,RRAGB,TAF15,TNRC6A,TPR,USP33,VPS13D,XRN1,YWHAB,ZMPSTE24 |
| GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 2.0e-07 | 2.4e-05 | 453 | 1177 | 31 | ADGRG6,BMPR2,CCN1,CCN2,CDK5,CDK5R1,COL11A1,CTR9,EMC10,EPHB4,GABPA,GPC1,HSPB1,LDB1,MED12,MYH9,NF2,PDGFRB,PHLDB2,PIK3C2A,PTGFRN,PTK7,RDH13,ROCK1,RTF1,S100A1,SYNPO2L,TMOD4,UBP1,WNT2B,ZNF385A |
| GO_GROWTH | 2.0e-07 | 2.4e-05 | 453 | 990 | 28 | ACACB,ANAPC2,ARHGEF11,BCL2,BMPR2,CDK5,CDK5R1,CLSTN1,CRABP2,CTR9,GIGYF2,HDGFL2,IGF1,MAP2K4,MED12,NDRG3,PDGFRB,PTCH2,PTGFRN,PTK7,PTPRS,RBBP7,RTF1,SHANK3,SIPA1,SRC,UBE2E3,ZMPSTE24 |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 2.0e-07 | 2.4e-05 | 453 | 1117 | 30 | ABCC5,ACACB,B3GNT8,BCL2,BMPR2,CHST10,COL11A1,DLD,DLG1,FASN,GAL3ST4,GBA,GLB1,GNMT,GNPTAB,GPC1,GXYLT1,HTD2,IGF1,JAK3,NCSTN,PANK2,PDE8A,PDGFRB,PDK2,RANBP2,RRM2B,SUCLA2,SULT1A3,TPR |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 2.0e-07 | 2.4e-05 | 453 | 1988 | 43 | AGER,AHRR,ARHGEF11,BICRA,BMPR2,BPTF,CCN1,CTR9,EPM2AIP1,ERCC3,GABPA,GBA,GLYR1,HMGN5,HSPB1,IGF1,KPNA6,LDB1,MAP2K4,MED12,MED25,MGA,MYO6,NAA16,NCSTN,NPAT,OTX1,PDGFRB,PHF10,PHF8,POU2F2,PTH1R,RNASEL,RNF20,RTF1,SMARCC2,SMARCD1,SRC,TAF15,TFAP2E,TRIM24,TRPV1,USF1 |
| GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 2.0e-07 | 2.4e-05 | 453 | 995 | 28 | AGER,BCL2,BMPR2,BPTF,CASP2,CDK5,CDK5R1,DCTN1,GIGYF2,HDAC10,ID3,KRAS,LDB1,MED12,MYO1D,NCSTN,NF2,NRGN,OTX1,PHF8,PTPRS,S100A1,SHANK3,SLITRK5,SRC,SRD5A1,WNT2B,ZIC4 |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 2.0e-07 | 2.7e-05 | 453 | 1859 | 41 | ABCC5,ACACB,AGER,ALAD,B3GNT8,BCL2,BMPR2,CCN1,CHST10,DLD,FASN,GAL3ST4,GBA,GIGYF2,GPC1,GSTM4,GXYLT1,HSPB1,HTD2,IDO2,IGF1,JAK3,KLHL25,LCAT,LDB1,NANOS3,NCSTN,NMNAT3,PANK2,PDGFRB,PDK2,PRKD3,PTDSS2,RD3,ROCK1,SUCLA2,TNRC6A,TPR,XRN1,ZDHHC3,ZNF385A |
| GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 2.0e-07 | 2.7e-05 | 453 | 942 | 27 | APC,BECN1,CARMIL1,CCN1,CCN2,CDK5R1,CLSTN1,DCTN1,DLG1,ELN,ERCC3,GBA,LCAT,LDB1,MED25,NF2,PHLDB2,PTPRS,ROCK1,SHANK3,SLITRK5,SRC,SYNPO2L,TBCD,TERF1,TMOD4,TPR |
| GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION | 2.0e-07 | 3.3e-05 | 453 | 194 | 12 | CARMIL1,CCN2,ELN,EPB41L1,MYH9,NF2,PDGFRB,PHLDB2,ROCK1,SRC,SYNPO2L,TMOD4 |
| GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 3.0e-07 | 4.0e-05 | 453 | 564 | 20 | ACAA1,BCL2,BECN1,CAT,GCC2,GNPTAB,IPO13,KPNA6,MBTPS1,NPAP1,PPP1R13B,RANBP17,RANBP2,TERF1,TPR,TSPAN17,USP46,VPS13D,VPS36,YWHAB |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 4.0e-07 | 4.7e-05 | 453 | 1033 | 28 | ABHD12,ACACB,DLD,DLG1,FASN,HTD2,IDO2,IGF1,LCAT,NMNAT3,PANK2,PDE8A,PDGFRB,PDK2,PI4KA,PIK3C2A,PISD,PLCB3,PLD2,PTDSS2,PTH1R,RANBP2,RD3,RRM2B,SRC,SUCLA2,SULT1A3,TPR |
| GO_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 4.0e-07 | 4.7e-05 | 453 | 282 | 14 | ACACB,B3GNT8,EPM2AIP1,GLB1,GNMT,GNPTAB,GNPTG,IGF1,PDK2,PHKA2,PTH1R,RANBP2,SRC,ZMPSTE24 |
| GO_RESPONSE_TO_PEPTIDE | 4.0e-07 | 5.3e-05 | 453 | 525 | 19 | AGER,APC,ATP6V1B1,CAT,CCN2,CDK5,EPM2AIP1,GGH,IGF1,JAK3,PDK2,PIK3C2A,ROCK1,SRC,SRD5A1,SRSF5,TRPV1,TSHR,USF1 |
| GO_RESPONSE_TO_ABIOTIC_STIMULUS | 5.0e-07 | 5.3e-05 | 453 | 1235 | 31 | ABHD12,AGER,ALAD,BCL2,BECN1,CASP2,CAT,CCN2,CDK5,COL11A1,ERCC3,GBA,GNA11,IGF1,KRAS,MAP2K4,PDGFRB,POLB,POLH,RANBP2,RBBP7,RDH13,SHANK3,SIPA1,SLC12A2,SRC,TPR,TRPV1,USF1,USP28,ZMPSTE24 |
| GO_PROTEOLYSIS | 5.0e-07 | 5.3e-05 | 453 | 1779 | 39 | ADAMTS10,ADAMTSL3,AGER,ALAD,ANAPC2,AOPEP,APC,BECN1,BIRC6,CASP2,CCN1,CCN2,CD2AP,CDK5,CTSV,DLD,ECE1,FBXL20,GBA,GGH,GPS1,KLHL25,MBTPS1,MYH9,NCSTN,PACSIN3,PCYOX1,PISD,POLB,RNF20,ROCK1,SPP2,SRC,USP28,USP33,USP34,USP46,VPS36,ZMPSTE24 |
| GO_RESPONSE_TO_ANTIBIOTIC | 5.0e-07 | 5.3e-05 | 453 | 331 | 15 | ALAD,BCL2,BECN1,CAT,FDX1,GGH,ID3,PDE8A,PDGFRB,POLB,RSRC1,SRC,SRD5A1,USP46,XRN1 |
| GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 5.0e-07 | 5.3e-05 | 453 | 526 | 19 | ACACB,ALAD,BCL2,BECN1,BMPR2,CAT,CTSV,GBA,PDK2,RRAGB,SIPA1,SRC,SRD5A1,TNRC6A,TRIM24,TRPV1,USF1,USP33,WNT2B |
| GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 5.0e-07 | 5.6e-05 | 453 | 748 | 23 | ANAPC2,BCL2,BMPR2,CARMIL1,CDK5,CDK5R1,CRABP2,EPHA10,GPC1,KIDINS220,MYH9,PITPNA,POF1B,PTPRS,RHOBTB3,ROCK1,SHANK3,SLITRK5,SPAST,SRC,TBCD,USP33,ZNF385A |
| GO_CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | 5.0e-07 | 6.0e-05 | 453 | 1180 | 30 | ALAD,ANAPC2,BIRC6,CD2AP,CTSV,DDX5,DIS3L,DROSHA,FBXL20,GBA,GIGYF2,GPC1,HSPB1,KLHL25,LAPTM4B,NANOS3,NRDE2,PCYOX1,RNF20,ROCK1,TAF15,TNRC6A,USP28,USP33,USP34,USP46,VPS36,XRN1,YWHAB,ZMPSTE24 |
| GO_POSITIVE_REGULATION_OF_SIGNALING | 6.0e-07 | 6.6e-05 | 453 | 1869 | 40 | AGER,BCL2,BECN1,BMPR2,CASP2,CAT,CC2D1A,CCN1,CCN2,CDK5,CLSTN1,DDX5,ECE1,EMC10,GBA,IGF1,INCA1,KIDINS220,KIF7,KRAS,LASP1,LRRC19,MAP2K4,MAPK8IP3,MCU,MID1,NCSTN,NRGN,PDE8A,PDGFRB,PPP1R13B,PTK7,ROCK1,RRAGB,SHANK3,SRC,SYNPO2L,USP34,YWHAB,ZNF385A |
| GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 6.0e-07 | 6.9e-05 | 453 | 537 | 19 | AKAP5,APC,BCL2,CD2AP,CDK5,CDK5R1,CEP131,CNPY4,DLG1,GCC2,GPC1,NF2,PPP1R13B,SRC,STAC3,TERF1,TPR,USP46,YWHAB |
| GO_REGULATION_OF_CELL_DIFFERENTIATION | 7.0e-07 | 7.5e-05 | 453 | 1881 | 40 | AGER,ANAPC2,APC,BCL2,BMPR2,CARMIL1,CCN1,CCN2,CDK5,CDK5R1,CLPTM1,CRABP2,CTR9,CTSV,DDX5,DROSHA,FOXE3,GABPA,GNA11,GPC1,ID3,IGF1,JAK3,KIDINS220,KRAS,LDB1,LRRC17,NF2,PHLDB2,PTBP3,PTCH2,PTK7,PTPRS,ROCK1,SHANK3,SPEN,TMEM64,TNRC6A,TRPV1,ZNF385A |
| GO_ACTIN_FILAMENT_ORGANIZATION | 8.0e-07 | 8.4e-05 | 453 | 393 | 16 | ARHGAP17,BCL2,CARMIL1,CCN2,CD2AP,DLG1,ELN,NF2,PHLDB2,POF1B,RHOBTB3,ROCK1,SHANK3,SRC,SYNPO2L,TMOD4 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 8.0e-07 | 8.6e-05 | 453 | 1823 | 39 | AGER,APC,BCL2,BMPR2,CCDC88C,CCN1,CCN2,CCNL2,CCNQ,CDK5,CDK5R1,DLG1,DYNAP,EMC10,GBA,GPS1,HRH4,HSPB1,IGF1,INCA1,KIDINS220,KRAS,LDB1,MAP2K4,MAPK8IP3,MID1,MYO1D,NF2,PDE8A,PDGFRB,PDK2,PPP2R3A,PTH1R,RANBP2,RD3,ROCK1,SRC,TPR,YWHAB |
| GO_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 8.0e-07 | 8.6e-05 | 453 | 444 | 17 | AGER,ANAPC2,CDK5,CLSTN1,FBXL20,GIT1,KRAS,NCSTN,NISCH,NRGN,PACSIN2,PTPRS,SHANK3,SHISA9,SRC,USP46,VAMP1 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 9.0e-07 | 8.6e-05 | 453 | 831 | 24 | ACACB,ALAD,ATP6V1B1,BCL2,BECN1,CDK5,CDK5R1,GBA,GIGYF2,HSPB1,IGF1,LAPTM4B,NANOS3,NRDE2,PACSIN3,ROCK1,RRAGB,TAF15,TNRC6A,USP33,VPS13D,XRN1,YWHAB,ZMPSTE24 |
| GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 1.0e-06 | 9.4e-05 | 453 | 181 | 11 | BCL2,CDK5,CDK5R1,DDX5,PPP1R13B,RBBP7,RRM2B,TAF15,TRIM24,ZMPSTE24,ZNF385A |
| GO_CELLULAR_RESPONSE_TO_STARVATION | 1.0e-06 | 9.8e-05 | 453 | 146 | 10 | BCL2,BECN1,BMPR2,CTSV,GBA,RRAGB,SRD5A1,TNRC6A,USP33,WNT2B |
| GO_CHROMOSOME_ORGANIZATION | 1.1e-06 | 1.1e-04 | 453 | 1223 | 30 | AEBP2,APC,BECN1,BPTF,CDK5,CTR9,ERCC3,GLYR1,GPS1,HDAC10,HMGN5,KMT5C,LDB1,MORC2,NAA60,NRDE2,PHF10,PHF8,PWWP3A,RBBP7,RCOR1,RNF20,RTF1,SMARCC2,SMARCD1,SRC,TERF1,TPR,XRN1,ZMPSTE24 |
| GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 1.1e-06 | 1.0e-04 | 453 | 724 | 22 | APC,BECN1,CARMIL1,CDK5,CDK5R1,GBA,IGF1,LRPAP1,MID1,PACSIN2,PACSIN3,PHF8,PHLDB2,PTPRS,ROCK1,SHANK3,SRC,TBCD,TERF1,TMOD4,TPR,XRN1 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 1.3e-06 | 1.3e-04 | 453 | 620 | 20 | ACACB,B3GNT8,CHST10,EPM2AIP1,GAL3ST4,GLB1,GNMT,GNPTAB,GNPTG,IGF1,NISCH,PDK2,PHKA2,PTH1R,RANBP2,SRC,TPR,UGT2A1,USF1,ZMPSTE24 |
| GO_CHROMATIN_ORGANIZATION | 1.4e-06 | 1.3e-04 | 453 | 795 | 23 | AEBP2,BPTF,CDK5,CTR9,GLYR1,HDAC10,HMGN5,KMT5C,LDB1,MORC2,NAA60,NRDE2,PHF10,PHF8,PWWP3A,RBBP7,RCOR1,RNF20,RTF1,SMARCC2,SMARCD1,TPR,ZMPSTE24 |
| GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 1.5e-06 | 1.4e-04 | 453 | 569 | 19 | ARHGAP17,ARHGEF11,ARHGEF40,CD2AP,GARNL3,IGF1,KRAS,NISCH,PDGFRB,PLD2,RAB40AL,RAB40B,RALGPS2,RHOBTB3,ROCK1,SIPA1,SRC,SYNPO2L,USP28 |
| GO_AGING | 1.9e-06 | 1.7e-04 | 453 | 323 | 14 | AGER,BCL2,BECN1,CASP2,CAT,CCN2,CTSV,DLD,KRAS,PDGFRB,POLB,PTH1R,SLC12A2,ZMPSTE24 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 1.9e-06 | 1.7e-04 | 453 | 122 | 9 | AKAP5,BCL2,CDK5,CDK5R1,CNPY4,DLG1,PPP1R13B,STAC3,YWHAB |
| GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 2.0e-06 | 1.8e-04 | 453 | 637 | 20 | APC,BCL2,CASP2,CDK5,CDK5R1,DLG1,FOXE3,GIGYF2,HMGN5,INCA1,MED25,MGA,PPP1R13B,RBBP7,RRAGB,SIPA1,TERF1,TPR,USP28,ZNF385A |
| GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 2.0e-06 | 1.8e-04 | 453 | 526 | 18 | APC,BECN1,CARMIL1,CCN2,CDK5R1,CLSTN1,DCTN1,DLG1,ERCC3,MED25,NF2,PHLDB2,ROCK1,SLITRK5,SRC,SYNPO2L,TERF1,TPR |
| GO_RESPONSE_TO_DRUG | 2.0e-06 | 1.8e-04 | 453 | 1061 | 27 | ACACB,ALAD,BCL2,BECN1,CAT,CDK5,CDK5R1,FDX1,GABPA,GBA,GGH,GNA11,HRH4,MYO6,NCSTN,PDE8A,PDGFRB,POLB,RANBP2,SLC4A11,SRC,SRD5A1,SULT1A3,TERF1,TRPV1,USP46,XRN1 |
| GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 2.1e-06 | 1.8e-04 | 453 | 326 | 14 | AKAP5,APC,BCL2,CD2AP,CDK5,CDK5R1,CEP131,CNPY4,DLG1,PPP1R13B,SRC,STAC3,TPR,YWHAB |
| GO_ANIMAL_ORGAN_MORPHOGENESIS | 2.4e-06 | 2.0e-04 | 453 | 1071 | 27 | ADGRG6,ATP6V1B1,BCL2,BMPR2,CCN1,CCN2,COL11A1,DLG1,ELN,EPHB4,FOXE3,GBA,HOXB6,ID3,KRAS,MED12,NF2,OTX1,PDGFRB,POLB,PTK7,RDH13,SHANK3,SRC,SYNPO2L,WNT2B,ZMPSTE24 |
| GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 2.7e-06 | 2.2e-04 | 453 | 649 | 20 | BIRC6,BMPR2,BPTF,CCN1,CDK5R1,COL11A1,CTR9,DLG1,ECE1,GABPA,HOXB6,IGF1,KIDINS220,MED12,MYH9,NPAT,POLB,PTH1R,PTK7,RTF1 |
| GO_EMBRYONIC_MORPHOGENESIS | 2.7e-06 | 2.2e-04 | 453 | 592 | 19 | ATP6V1B1,BMPR2,CCN1,COL11A1,CRABP2,CTR9,DLD,DLG1,ECE1,HOXB6,LDB1,MED12,NF2,OTX1,PHLDB2,PTK7,ROCK1,RTF1,WNT2B |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 2.9e-06 | 2.4e-04 | 453 | 1559 | 34 | ABHD12,AGER,BCL2,CCN2,DDX5,DLG1,DROSHA,DUOX1,EMC10,FAM168A,GBA,HDAC10,HSPB1,IGF1,KPNA6,KRAS,LRRC19,MAP2K4,MAPK8IP3,MID1,MYH9,PDE8A,PHLDB2,POLH,PTPRS,RANBP2,RNASEL,S100A1,SRC,SYTL4,TPR,USF1,ZMPSTE24,ZNF385A |
| GO_BEHAVIOR | 3.1e-06 | 2.5e-04 | 453 | 598 | 19 | ABHD12,AGER,ATP6V1B1,BCL2,CDK5,DCTN1,FBXL20,GIGYF2,GRPR,KRAS,NCSTN,NRGN,SHANK3,SLITRK5,SRD5A1,TRPV1,USP46,ZMPSTE24,ZNF385A |
| GO_RESPONSE_TO_PEPTIDE_HORMONE | 3.1e-06 | 2.5e-04 | 453 | 436 | 16 | APC,ATP6V1B1,CAT,CCN2,EPM2AIP1,GGH,JAK3,PDK2,PIK3C2A,ROCK1,SRC,SRD5A1,SRSF5,TRPV1,TSHR,USF1 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 3.2e-06 | 2.5e-04 | 453 | 1781 | 37 | AGER,AKAP5,ARHGAP17,ARHGEF11,BCL2,CAT,CCN1,CCN2,CDK5,CDK5R1,DLG1,DYNAP,DYNLL2,EPM2AIP1,GARNL3,GIT1,IGF1,KCNIP2,KIDINS220,KRAS,MAP2K4,MAPK8IP3,MED25,NCSTN,PDGFRB,PPP1R12B,RANBP2,RIC8B,S100A1,SHANK3,SIPA1,SRC,STAC3,TBC1D13,TBCD,USP33,YWHAB |
| GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 3.3e-06 | 2.6e-04 | 453 | 98 | 8 | CARMIL1,CCN2,ELN,NF2,PHLDB2,ROCK1,SRC,SYNPO2L |
| GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 3.4e-06 | 2.7e-04 | 453 | 547 | 18 | ACAA1,ACACB,BCL2,CAT,DUOX1,FASN,FDX1,GBA,IGF1,LCAT,MBTPS1,NAAA,PANK2,PLCB3,PTH1R,RDH13,SRD5A1,SULT1A3 |
| GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 3.5e-06 | 2.7e-04 | 453 | 1030 | 26 | BCL2,BECN1,BIRC6,CASP2,CAT,CCN1,CCN2,CDK5,FOXE3,GBA,HMGN5,HSPB1,IGF1,JAK3,KRAS,LRPAP1,MAP2K4,NAA16,NANOS3,PDE8A,PDGFRB,ROCK1,RRM2B,SRC,SULT1A3,ZNF385A |
| GO_NEURON_DIFFERENTIATION | 3.6e-06 | 2.7e-04 | 453 | 1365 | 31 | AGER,ANAPC2,BCL2,BECN1,BMPR2,CDK5,CDK5R1,CRABP2,EPHA10,ERCC3,GIGYF2,GPC1,GPRIN1,ID3,KCNIP2,KIDINS220,LDB1,MAPK8IP3,PITPNA,PTK7,PTPRS,RDH13,RHOBTB3,ROCK1,SHANK3,SLITRK5,SPAST,SRC,TBCD,USP33,WNT2B |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 3.8e-06 | 2.9e-04 | 453 | 1301 | 30 | ABHD12,ALAD,ANAPC2,APC,BIRC6,CD2AP,CTSV,DLD,ECE1,FBXL20,GBA,GLB1,GPC1,HIBCH,IDO2,KLHL25,LAPTM4B,PACSIN3,PCYOX1,PDE8A,RNF20,ROCK1,SULT1A3,TRIM24,USP28,USP33,USP34,USP46,VPS36,ZMPSTE24 |
| GO_CIRCULATORY_SYSTEM_PROCESS | 4.1e-06 | 3.1e-04 | 453 | 554 | 18 | AGER,AOPEP,BMPR2,CCN2,DLG1,ECE1,ELN,KCNIP2,KCNJ8,NISCH,PIK3C2A,PLCB3,ROCK1,S100A1,SRC,TMIGD3,TRPV1,ZMPSTE24 |
| GO_OSSIFICATION | 4.2e-06 | 3.1e-04 | 453 | 396 | 15 | ATP6V1B1,BCL2,BMPR2,CAT,CCN1,CCN2,CHRDL1,COL11A1,DDX5,FASN,ID3,IGF1,PTH1R,TMEM64,ZMPSTE24 |
| GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 4.2e-06 | 3.1e-04 | 453 | 976 | 25 | AGER,APC,CCN1,CCNL2,CCNQ,CDK5,CDK5R1,DLG1,DYNAP,EPM2AIP1,GBA,GPS1,HSPB1,IGF1,INCA1,KIDINS220,KRAS,LDB1,MAP2K4,MAPK8IP3,NF2,PDGFRB,RANBP2,SRC,TERF1 |
| GO_COFACTOR_METABOLIC_PROCESS | 4.4e-06 | 3.2e-04 | 453 | 449 | 16 | ACACB,ALAD,CAT,DLD,DUOX1,FASN,GGH,GNMT,GSTM4,GSTT2,HTD2,IDO2,NMNAT3,PANK2,PDK2,SUCLA2 |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 4.4e-06 | 3.2e-04 | 453 | 1880 | 38 | AGER,APC,BCL2,BMPR2,CCDC88C,CCN1,CCN2,CCNL2,CCNQ,CDK5,CDK5R1,CTR9,DLG1,DYNAP,EMC10,FAM161A,GBA,GLYR1,GPS1,HRH4,HSPB1,IGF1,INCA1,KIDINS220,KRAS,MAP2K4,MAPK8IP3,MID1,NF2,PDE8A,PDGFRB,PPP2R3A,RNF20,ROCK1,RTF1,SRC,YWHAB,ZMPSTE24 |
| GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II | 5.1e-06 | 3.6e-04 | 453 | 860 | 23 | AEBP2,AHRR,BPTF,CC2D1A,CTR9,DDX5,DLG1,GABPA,HDAC10,ID3,LDB1,MED25,MGA,PARP15,RBBP7,RCOR1,RTF1,S100A1,SPEN,TPR,TRPV1,ZNF224,ZNF8 |
| GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 6.2e-06 | 4.4e-04 | 453 | 220 | 11 | APC,BICD2,CDK5R1,CEP131,DCTN1,MID1,PHLDB2,SPAST,TBCD,TERF1,TPR |
| GO_REGULATION_OF_KINASE_ACTIVITY | 6.4e-06 | 4.4e-04 | 453 | 872 | 23 | AGER,APC,CCN1,CCNL2,CCNQ,CDK5,CDK5R1,DLG1,DYNAP,GBA,GPS1,HSPB1,IGF1,INCA1,KIDINS220,KRAS,LDB1,MAP2K4,MAPK8IP3,NF2,PDGFRB,RANBP2,SRC |
| GO_IMPORT_INTO_CELL | 6.5e-06 | 4.4e-04 | 453 | 810 | 22 | AGER,ATP9B,BECN1,CARMIL1,CD2AP,CDK5,DLG1,GPR107,KCNJ8,LRPAP1,MYH9,MYO6,PACSIN2,PACSIN3,PIK3C2A,RHOBTB3,ROCK1,SLC12A2,SRC,TRPV1,USP33,USP46 |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 6.5e-06 | 4.4e-04 | 453 | 463 | 16 | ACACB,CARMIL1,DLD,DLG1,FASN,GNMT,HTD2,IGF1,PANK2,PDE8A,PDK2,RANBP2,RD3,SUCLA2,SULT1A3,TPR |
| GO_ADULT_BEHAVIOR | 6.6e-06 | 4.4e-04 | 453 | 142 | 9 | ABHD12,ATP6V1B1,CDK5,GIGYF2,NCSTN,SHANK3,SLITRK5,USP46,ZMPSTE24 |
| GO_REGULATION_OF_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 6.6e-06 | 4.4e-04 | 453 | 142 | 9 | ACACB,EPM2AIP1,GNMT,IGF1,PDK2,PTH1R,RANBP2,SRC,ZMPSTE24 |
| GO_CELL_PART_MORPHOGENESIS | 6.8e-06 | 4.5e-04 | 453 | 691 | 20 | ANAPC2,BCL2,BMPR2,CDK5,CDK5R1,CRABP2,EPHA10,GPC1,KIDINS220,PACSIN2,PANK2,PITPNA,PTPRS,RHOBTB3,ROCK1,SHANK3,SLITRK5,SPAST,SRC,USP33 |
| GO_MEMBRANE_ORGANIZATION | 6.8e-06 | 4.5e-04 | 453 | 875 | 23 | ATP8B2,ATP9B,BCL2,BECN1,DCTN1,DLG1,KCNIP2,LAPTM4B,MYH9,PACSIN2,PACSIN3,PI4KA,PIK3C2A,PPP1R13B,RHOBTB3,SAMD9,SHANK3,SPAST,SYTL4,TGOLN2,VAMP1,YWHAB,ZMPSTE24 |
| GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR | 7.3e-06 | 4.8e-04 | 453 | 78 | 7 | BCL2,DDX5,PDK2,PPP1R13B,RRM2B,USP28,ZNF385A |
| GO_AXON_DEVELOPMENT | 7.5e-06 | 4.9e-04 | 453 | 523 | 17 | ANAPC2,BCL2,BMPR2,CDK5,CDK5R1,CRABP2,EPHA10,GPC1,MAPK8IP3,PITPNA,PTPRS,RHOBTB3,SHANK3,SLITRK5,SPAST,SRC,USP33 |
Num: 17 (Pathways: 23 DK: 2)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (2) | PKN3, TSSK3 |
| Light Kinase (14) | AKT2, BMPR1A, DGKH, DGKI, HIPK2, IRAK1, MAP3K3, MAP4K3, PDPK1, PIK3CA, RIPK1, SIK2, TRRAP, WNK1 |
| Non-kinase Count | 276 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_POSITIVE_REGULATION_OF_SIGNALING | 0.0e+00 | 3.3e-06 | 292 | 1869 | 36 | ARHGAP1,ATP6V0C,BMPR1A,CMTM3,CSF1,DDRGK1,DGKI,EP300,GOLPH3,HIPK2,HRAS,IRAK1,ITPKB,MAML1,MAP3K3,MAP4K3,MDFIC,NMNAT1,NUMA1,PIK3CA,PPP2R1A,PRRT2,RAB34,RFNG,RIPK1,RWDD3,SORBS3,SOS1,SOS2,SPOP,STAP2,STX4,TGFB1I1,TRIM8,TRIP6,WNK1 |
| GO_POSITIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 1.3e-05 | 292 | 1870 | 34 | AIP,ARID1B,ATF6B,BMPR1A,DDRGK1,DXO,EP300,EXOSC6,HIPK2,HMBOX1,HMGB3,HRAS,IRAK1,KAT6B,MAML1,MDFIC,MED16,MEX3D,NANOG,NCOA2,PHF2,PLEKHN1,RAI1,RIPK1,SETD7,STAT6,TEAD2,TEAD3,TGFB1I1,XRCC1,ZBED1,ZBTB38,ZFPM2,ZXDA |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 1.3e-05 | 292 | 1880 | 34 | AKT2,BMPR1A,CDK2AP1,CSF1,CTDSP1,CTDSPL,DAZAP2,DDRGK1,EDNRB,EP300,HIPK2,HRAS,IRAK1,ITPKB,MAP3K3,MAP4K3,MDFIC,NMNAT1,PDPK1,PHF23,PIK3CA,PPP2R1A,PPP2R2D,PPP4R1,PRKAR1A,RIPK1,RWDD3,SAMSN1,SETD7,SORBS3,STAP2,WNK1,XRCC1,ZMYND11 |
| GO_PROTEIN_PHOSPHORYLATION | 0.0e+00 | 1.3e-05 | 292 | 1994 | 35 | AKT2,BMPR1A,CDK2AP1,CSF1,CTDSP1,CTDSPL,DAZAP2,DDRGK1,EDNRB,HIPK2,HRAS,IRAK1,ITPKB,MAML1,MAP3K3,MAP4K3,MDFIC,NMNAT1,NRAS,PDPK1,PHKB,PIK3CA,PKN3,PPP2R1A,PPP4R1,PRKAR1A,RIPK1,SAMSN1,SIK2,SORBS3,SOS1,STAP2,TSSK3,WNK1,ZMYND11 |
| GO_POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 0.0e+00 | 1.3e-05 | 292 | 1710 | 32 | AIP,ARID1B,ATF6B,BMPR1A,DDRGK1,DXO,EP300,HIPK2,HMBOX1,HMGB3,HRAS,IRAK1,KAT6B,MAML1,MDFIC,MED16,MEX3D,NANOG,NCOA2,PHF2,PLEKHN1,RAI1,RIPK1,SETD7,STAT6,TEAD2,TEAD3,TGFB1I1,ZBED1,ZBTB38,ZFPM2,ZXDA |
| GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 0.0e+00 | 2.3e-05 | 292 | 1051 | 24 | AKT2,ARPC1B,ARPC4,ATP6V0C,BMPR1A,CSF1,EP300,FUZ,HIPK2,HRAS,IRAK1,NUMA1,PDPK1,PIK3CA,RNF115,SIK2,SIPA1L1,SOS1,STAT6,TGFB1I1,TIA1,TMEM204,ZFYVE9,ZYX |
| GO_LOCOMOTION | 1.0e-07 | 8.8e-05 | 292 | 1984 | 33 | AKT2,ARSB,BMPR1A,CATSPER1,CERS2,CHMP3,CLASP1,CMTM3,CSF1,DDRGK1,EDNRB,EP300,FAM83H,FMNL1,FUZ,GOLPH3,HRAS,MAP3K3,MMP14,MST1L,NEXN,PARVA,PDPK1,PIK3CA,PKN3,RIPOR1,SOS1,STX4,TGFB1I1,TRIM8,TRIP6,WDR1,WNK1 |
| GO_CYTOSKELETON_ORGANIZATION | 1.0e-07 | 1.0e-04 | 292 | 1335 | 26 | ADD1,ARPC1B,ARPC4,CHMP3,CLASP1,CNP,FAM83H,FHL3,FMNL1,HRAS,LZTS2,NEXN,NUMA1,PARVA,PDPK1,PPP2R1A,PRKAR1A,SHROOM1,SIPA1L1,SORBS2,SORBS3,TPM2,TTLL11,WDR1,WIPF1,ZYX |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1.0e-07 | 1.1e-04 | 292 | 1823 | 31 | AKT2,BMPR1A,CDK2AP1,CSF1,CTDSP1,CTDSPL,DAZAP2,DDRGK1,EDNRB,HIPK2,HRAS,IRAK1,ITPKB,MAP3K3,MAP4K3,MDFIC,MTMR1,NMNAT1,PDPK1,PDPR,PIK3CA,PPP2R1A,PPP2R2D,PPP4R1,PRKAR1A,RIPK1,SAMSN1,SORBS3,STAP2,WNK1,ZMYND11 |
| GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 2.0e-07 | 1.1e-04 | 292 | 1267 | 25 | ADD1,AKT2,ARPC1B,ARPC4,ATL3,ATXN2,CHMP3,CLASP1,FUZ,GOLPH3,HMBOX1,HRAS,NEXN,NUMA1,PHF2,PHF23,PRKAR1A,PRRT2,RAB1B,RABEP2,RESF1,SETD7,SORBS3,WDR1,XRCC1 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 2.0e-07 | 1.7e-04 | 292 | 1781 | 30 | ADD1,AKT2,ARHGAP1,ARHGAP31,CARD8,CSF1,DAZAP2,DDRGK1,EP300,HIPK2,HMBOX1,HRAS,IRAK1,MAP3K3,MAP4K3,MAU2,MDFIC,NAPA,PDPK1,PIK3CA,PRKAR1A,RABEP2,RFNG,RIPK1,SIPA1L1,SOS1,STX4,TRIM8,WNK1,XRCC1 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 4.0e-07 | 2.7e-04 | 292 | 1930 | 31 | AIP,AKT2,ANKRD13C,AP1M2,AP4M1,DDRGK1,FAM83H,GOLPH3,HOMER3,HRAS,LZTS2,MAU2,MDFIC,MEX3D,MMP14,NAGPA,NAPA,NUMA1,PDPK1,PTPN9,RAB11B,RAB1B,RAB22A,RAB34,RIPOR1,STX4,TCTN2,TIA1,TRIM8,VTI1B,WIPI2 |
| GO_CELL_MOTILITY | 6.0e-07 | 3.0e-04 | 292 | 1758 | 29 | AKT2,ARSB,BMPR1A,CATSPER1,CERS2,CLASP1,CSF1,DDRGK1,EDNRB,FAM83H,FMNL1,FUZ,GOLPH3,HRAS,MAP3K3,MMP14,MST1L,NEXN,PARVA,PDPK1,PIK3CA,PKN3,RIPOR1,SOS1,STX4,TGFB1I1,TRIP6,WDR1,WNK1 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 6.0e-07 | 3.0e-04 | 292 | 1863 | 30 | AIP,ARHGAP1,ARHGAP31,CARD8,CSF1,DDRGK1,DGKI,EP300,GOLPH3,HIPK2,HOMER3,HRAS,IRAK1,ITPKB,MAP3K3,MAP4K3,MDFIC,NMNAT1,PDPK1,PIK3CA,PPP2R1A,RIPK1,SIPA1L1,SORBS3,SOS1,SOS2,SPOP,TRIM8,TRIP6,ZMYND11 |
| GO_NEGATIVE_REGULATION_OF_RNA_BIOSYNTHETIC_PROCESS | 7.0e-07 | 3.0e-04 | 292 | 1280 | 24 | COMMD7,EDNRB,EP300,FAM172A,HIPK2,HMBOX1,HOXC6,HSBP1L1,KAT6B,MDFIC,NANOG,NCOA2,PHF2,POU6F1,RESF1,SORBS3,SPOP,STAT6,TCF25,ZBTB1,ZBTB38,ZFPM2,ZMYND11,ZMYND15 |
| GO_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 7.0e-07 | 3.0e-04 | 292 | 1470 | 26 | COMMD7,EDNRB,EP300,FAM172A,HIPK2,HMBOX1,HOXC6,HSBP1L1,KAT6B,MDFIC,NANOG,NCOA2,NMNAT1,PHF2,POU6F1,RESF1,SORBS3,SPOP,STAT6,TCF25,XRCC1,ZBTB1,ZBTB38,ZFPM2,ZMYND11,ZMYND15 |
| GO_VESICLE_ORGANIZATION | 7.0e-07 | 3.0e-04 | 292 | 330 | 12 | AKT2,CHMP3,COL7A1,GOLPH3,NAPA,PRRT2,RAB1B,RAB22A,RAB34,SNX3,STX4,VTI1B |
| GO_ACTIN_FILAMENT_BASED_PROCESS | 8.0e-07 | 3.2e-04 | 292 | 766 | 18 | ADD1,ARPC1B,ARPC4,CLASP1,FHL3,FMNL1,HRAS,PARVA,PDPK1,PRKAR1A,SHROOM1,SIPA1L1,SORBS2,SORBS3,TPM2,WDR1,WIPF1,ZYX |
| GO_POSITIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS | 8.0e-07 | 3.2e-04 | 292 | 1988 | 31 | AIP,AKT2,ARID1B,ATF6B,BMPR1A,DDRGK1,EP300,HIPK2,HMBOX1,HMGB3,HRAS,IRAK1,KAT6B,MAML1,MDFIC,MED16,NANOG,NCOA2,PHF2,RAI1,RIPK1,SETD7,STAT6,TEAD2,TEAD3,TGFB1I1,TRUB2,ZBED1,ZBTB38,ZFPM2,ZXDA |
| GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 9.0e-07 | 3.3e-04 | 292 | 1026 | 21 | CSF1,DDRGK1,DGKI,EP300,GOLPH3,HIPK2,HRAS,IRAK1,ITPKB,MAP3K3,MAP4K3,MDFIC,NMNAT1,PIK3CA,RIPK1,SORBS3,SOS1,SOS2,SPOP,TRIM8,TRIP6 |
| GO_ORGANELLE_LOCALIZATION | 1.0e-06 | 3.6e-04 | 292 | 622 | 16 | AP1M2,CLASP1,COL7A1,NAPA,NUMA1,PDPK1,PPP2R1A,RAB11B,RAB1B,RAB34,RIPOR1,STARD3,STX4,TCTN2,VPS33A,VTI1B |
| GO_REGULATION_OF_PHOSPHORYLATION | 1.3e-06 | 4.6e-04 | 292 | 1625 | 27 | AKT2,BMPR1A,CDK2AP1,CSF1,CTDSP1,CTDSPL,DAZAP2,DDRGK1,EDNRB,HIPK2,HRAS,IRAK1,ITPKB,MAP3K3,MAP4K3,MDFIC,NMNAT1,PDPK1,PIK3CA,PPP2R1A,PRKAR1A,RIPK1,SAMSN1,SORBS3,STAP2,WNK1,ZMYND11 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1.5e-06 | 5.0e-04 | 292 | 1247 | 23 | AKT2,BMPR1A,CDK2AP1,CSF1,DAZAP2,DDRGK1,EDNRB,HIPK2,HRAS,IRAK1,MAP3K3,MAP4K3,MDFIC,NMNAT1,PDPK1,PHF23,PIK3CA,PRKAR1A,RIPK1,RWDD3,SORBS3,STAP2,WNK1 |
Num: 19 (Pathways: 68 DK: 2)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (2) | CSNK2A3, PRKACB |
| Light Kinase (3) | DGKQ, ERBB3, RPS6KA6 |
| Non-kinase Count | 370 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 375 | 1782 | 52 | ANXA2,ARL2,ATXN10,COA3,COG4,COX7A2,CYBA,DCXR,DGAT1,DGKQ,FADD,GPAA1,GPX4,H1-2,H2BC19P,H2BC21,H2BC5,H2BC6,H4C14,HDAC6,HMGCL,HOMER1,KCTD11,KCTD18,LIN7A,NDUFB1,NDUFB5,OXA1L,PEX5,PRKACB,PRUNE1,RBX1,SCO2,SKAP2,SLC2A1,STUB1,TAF10,TAF7,TAZ,TBCC,TBCEL,TGFB1,TIMMDC1,TLE4,TMEM120A,TMSB10,TRAPPC12,TRIM4,TWF2,UQCRB,VPS16,XPC |
| GO_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 375 | 1962 | 54 | ABHD14B,ACSBG1,AGPAT2,AKR7A2,APRT,ATP5F1C,ATP5F1E,ATP5PD,B3GALT6,BCAT2,CALM1,CARS2,COQ10A,COQ5,DALRD3,DCXR,DGAT1,DGKQ,DLG2,G6PC,GALK1,GALT,GPX4,GSTZ1,HMGCL,ISCA2,MBTPS2,MIDN,MPST,N6AMT1,NAXE,NDST2,NUDT14,OGDH,OXSM,PDHB,PPCS,PPP1CA,PPP1R3D,PRUNE1,PTEN,SFXN3,SLC16A3,SLC25A11,SLC2A1,SLC35B2,SMUG1,SRD5A3,TAZ,TECR,TGFB1,THTPA,TKFC,TYRP1 |
| GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 375 | 1033 | 38 | ABHD14B,ACSBG1,AGPAT2,APRT,ATP5F1C,ATP5F1E,ATP5PD,CALM1,CHKB,CPNE1,DCXR,DGAT1,DGKQ,DLG2,FIG4,G6PC,GALK1,GPAA1,GPX4,GSTZ1,HMGCL,NAXE,NUDT14,OGDH,OXSM,PDHB,PGAP3,PIP4P2,PPCS,PTEN,SLC35B2,SMUG1,SRD5A3,TAZ,TECR,TGFB1,THTPA,TKFC |
| GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 0.0e+00 | 0.0e+00 | 375 | 532 | 28 | AKR7A2,ATP5F1C,ATP5F1E,ATP5PD,CALM1,COQ10A,COX7A2,COX7C,CYBA,ETFRF1,G6PC,GALK1,HMGCL,NDUFA4L2,NDUFB1,NDUFB5,NIPSNAP2,OGDH,OXA1L,PDHB,PPP1CA,PPP1R3D,TAZ,THTPA,TYRP1,UQCR11,UQCRB,UQCRQ |
| GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 375 | 1117 | 37 | ABHD14B,ACSBG1,AGA,AKR7A2,APRT,ATP5F1C,ATP5F1E,ATP5PD,B3GALT6,DAD1,DCXR,DGAT1,DLG2,EDEM1,G6PC,GALK1,GALNT4,GALT,GPAA1,GSTZ1,HMGCL,MAN1B1,NAGA,NDST2,NUDT14,OGDH,OXSM,PDHB,PGAP3,PPCS,SLC35B2,SMUG1,SRD5A3,TAZ,TECR,TGFB1,TKFC |
| GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 0.0e+00 | 0.0e+00 | 375 | 1036 | 34 | ARL2,COA3,COG4,COX7A2,CYBA,DGKQ,GPX4,H1-2,H2BC19P,H2BC21,H2BC5,H2BC6,H4C14,HDAC6,NDUFB1,NDUFB5,OXA1L,PRUNE1,RBX1,SCO2,STUB1,TAF10,TAF7,TAZ,TBCC,TBCEL,TGFB1,TIMMDC1,TMSB10,TRAPPC12,TWF2,UQCRB,VPS16,XPC |
| GO_INTRACELLULAR_TRANSPORT | 0.0e+00 | 0.0e+00 | 375 | 1741 | 42 | ANXA2,AP1G2,AP1M1,AP4E1,ATP5F1C,ATP5F1E,ATP5PD,CDKN1A,CLBA1,COG4,CREB3L2,DLG2,DYNLRB1,EDEM1,EZR,HDAC6,HIKESHI,HMGCL,IFT22,IFT52,IFT88,MPV17,OXA1L,PEX5,PLEKHA8P1,RAB33B,SLC25A20,SNAPIN,SNX12,SNX15,SNX32,TBC1D25,TGFB1,TIMM8B,TMEM87B,TRAPPC12,TSG101,TTC30A,VPS16,VPS25,YIF1A,ZFAND6 |
| GO_COFACTOR_METABOLIC_PROCESS | 0.0e+00 | 0.0e+00 | 375 | 449 | 21 | ACSBG1,AKR7A2,CALM1,COQ10A,COQ5,CYBA,DGAT1,GPX4,GSTZ1,HDAC6,HMGCL,ISCA2,NAXE,OGDH,OXSM,PDHB,PPCS,PPOX,SLC2A1,TECR,THTPA |
| GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 375 | 627 | 24 | ABHD14B,ACSBG1,AGPAT2,APRT,ATP5F1C,ATP5F1E,ATP5PD,DGAT1,DLG2,GALK1,GALT,GSTZ1,HMGCL,NAXE,NUDT14,OGDH,OXSM,PDHB,PPCS,SLC35B2,SMUG1,TAZ,TECR,TGFB1 |
| GO_RIBOSE_PHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 1.0e-07 | 375 | 423 | 20 | ABHD14B,ACSBG1,APRT,ATP5F1C,ATP5F1E,ATP5PD,DGAT1,DLG2,GALK1,GSTZ1,HMGCL,NUDT14,OGDH,OXSM,PDHB,PPCS,SLC35B2,TAZ,TECR,TGFB1 |
| GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 1.0e-07 | 375 | 594 | 23 | ACSBG1,AGPAT2,APRT,ATP5F1C,ATP5F1E,ATP5PD,CHKB,CPNE1,DCXR,DGKQ,FIG4,GPAA1,GSTZ1,NAXE,PDHB,PGAP3,PPCS,PTEN,SLC35B2,SRD5A3,TAZ,TECR,TGFB1 |
| GO_OXIDATION_REDUCTION_PROCESS | 0.0e+00 | 1.0e-07 | 375 | 1005 | 30 | AKR7A2,CALM1,COQ10A,COX7A2,COX7C,CYBA,DCXR,ETFRF1,G6PC,GPX4,HSDL1,NDUFA4L2,NDUFB1,NDUFB5,OGDH,OXA1L,PDHB,PPOX,PPP1CA,PPP1R3D,RIOX1,SCO2,SDR39U1,SRD5A3,TAZ,TECR,TYRP1,UQCR11,UQCRB,UQCRQ |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 2.0e-07 | 375 | 1930 | 43 | ANXA2,AP1G2,AP1M1,AP4E1,ARL2,ARL2BP,BCL2L1,CDKN1A,DLG2,DYNLRB1,EDEM1,EZR,GET1,GPAA1,HDAC6,HIKESHI,HMGCL,IFT22,IFT52,IFT88,LAMTOR2,LAMTOR4,LAMTOR5,LIN7A,MPV17,NPHP4,OXA1L,PEX5,RAB33B,SNAPIN,SNX15,TBC1D25,TGFB1,TIMM8B,TMSB10,TRAPPC12,TSG101,TTC30A,TWF2,VAMP5,VPS16,VPS25,ZFAND6 |
| GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 0.0e+00 | 3.0e-07 | 375 | 278 | 16 | CALM1,COQ10A,COX7C,ETFRF1,G6PC,NDUFB1,NDUFB5,OGDH,OXA1L,PDHB,PPP1CA,PPP1R3D,TAZ,UQCR11,UQCRB,UQCRQ |
| GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 3.0e-07 | 375 | 463 | 20 | ABHD14B,ACSBG1,APRT,ATP5F1C,ATP5F1E,ATP5PD,DGAT1,DLG2,G6PC,GALK1,GSTZ1,HMGCL,OGDH,OXSM,PDHB,PPCS,SLC35B2,TAZ,TECR,TGFB1 |
| GO_PROTEOLYSIS | 0.0e+00 | 4.0e-07 | 375 | 1779 | 40 | AGA,ANXA2,ARRDC1,CHFR,CPNE1,DPP3,EDEM1,FADD,FAM122A,FBXL14,FBXL8,FBXW4,FBXW5,HDAC6,IFT52,JOSD2,LAMTOR5,MAN1B1,MBTPS2,PGPEP1,PRKACB,PRSS16,PTEN,RBX1,RNF187,RNF215,RNPEPL1,SNX12,SPPL2A,SPPL3,SPSB2,STUB1,TADA3,TAF10,TGFB1,TRAPPC12,TSG101,USP25,VPS25,ZNRF1 |
| GO_OXIDATIVE_PHOSPHORYLATION | 0.0e+00 | 5.0e-07 | 375 | 144 | 12 | ATP5F1C,ATP5F1E,ATP5PD,COX7A2,COX7C,NDUFB1,NDUFB5,NIPSNAP2,TAZ,UQCR11,UQCRB,UQCRQ |
| GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS | 0.0e+00 | 7.0e-07 | 375 | 1301 | 33 | ANXA2,ARRDC1,ATRAID,BCAT2,CHFR,EDEM1,EZR,FAM122A,FBXL14,FBXL8,FBXW4,FBXW5,GSTZ1,HDAC6,HMGCL,MAN1B1,MPST,NAGA,OGDH,PRSS16,PTEN,RBX1,RNF187,RNF215,SMUG1,SNX12,SPSB2,STUB1,TGFB1,TSG101,USP25,VPS25,ZNRF1 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 0.0e+00 | 9.0e-07 | 375 | 1114 | 30 | ARRDC1,CHFR,FBXL14,FBXL8,FBXW4,FBXW5,GPS2,H2BC5,H2BC6,HDAC6,JOSD2,KCTD11,MED11,MED7,PEX5,PTEN,RBX1,RING1,RNF135,RNF170,RNF187,RNF215,SPSB2,STUB1,TADA3,TAF10,TRIM4,TSG101,USP25,ZNRF1 |
| GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 0.0e+00 | 1.7e-06 | 375 | 372 | 17 | ABHD14B,ACSBG1,B3GALT6,DGAT1,GPX4,GSTZ1,HMGCL,ISCA2,MPST,NDST2,OGDH,OXSM,PDHB,PPCS,SLC35B2,TECR,THTPA |
| GO_MACROAUTOPHAGY | 0.0e+00 | 3.1e-06 | 375 | 295 | 15 | ATG16L2,ATP6V0D1,EPM2A,HDAC6,IFT88,LAMTOR2,LAMTOR4,LAMTOR5,RAB33B,SNAPIN,SNX32,TBC1D25,TSG101,VPS16,VPS25 |
| GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | 0.0e+00 | 3.1e-06 | 375 | 912 | 26 | ARRDC1,CHFR,FBXL14,FBXL8,FBXW4,FBXW5,GPS2,H2BC5,H2BC6,HDAC6,KCTD11,MED11,MED7,PEX5,PTEN,RBX1,RING1,RNF135,RNF170,RNF187,RNF215,SPSB2,STUB1,TRIM4,TSG101,ZNRF1 |
| GO_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS | 0.0e+00 | 3.2e-06 | 375 | 139 | 11 | ABHD14B,ACSBG1,DGAT1,GSTZ1,HMGCL,OGDH,OXSM,PDHB,PPCS,SLC35B2,TECR |
| GO_COENZYME_METABOLIC_PROCESS | 0.0e+00 | 3.2e-06 | 375 | 254 | 14 | ACSBG1,COQ10A,COQ5,DGAT1,GSTZ1,HMGCL,NAXE,OGDH,OXSM,PDHB,PPCS,SLC2A1,TECR,THTPA |
| GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 3.4e-06 | 375 | 671 | 22 | ACSBG1,APRT,ATP5F1C,ATP5F1E,ATP5PD,B3GALT6,DAD1,DCXR,GALNT4,GPAA1,GSTZ1,MAN1B1,NDST2,NUDT14,PDHB,PGAP3,PPCS,SLC35B2,SRD5A3,TAZ,TECR,TGFB1 |
| GO_ATP_METABOLIC_PROCESS | 0.0e+00 | 3.7e-06 | 375 | 303 | 15 | ATP5F1C,ATP5F1E,ATP5PD,COX7A2,COX7C,GALK1,NDUFB1,NDUFB5,NIPSNAP2,OGDH,TAZ,TGFB1,UQCR11,UQCRB,UQCRQ |
| GO_ELECTRON_TRANSPORT_CHAIN | 0.0e+00 | 5.4e-06 | 375 | 185 | 12 | AKR7A2,COX7A2,COX7C,CYBA,ETFRF1,NDUFA4L2,NDUFB1,NDUFB5,TAZ,UQCR11,UQCRB,UQCRQ |
| GO_CELLULAR_RESPIRATION | 0.0e+00 | 5.9e-06 | 375 | 187 | 12 | COQ10A,COX7C,ETFRF1,NDUFB1,NDUFB5,OGDH,OXA1L,PDHB,TAZ,UQCR11,UQCRB,UQCRQ |
| GO_TRANSMEMBRANE_TRANSPORT | 0.0e+00 | 5.9e-06 | 375 | 1604 | 35 | ABCB8,ANXA2,ATP5F1C,ATP5F1E,ATP5PD,ATP6V0D1,CALM1,COX7A2,COX7C,CYBA,DLG2,HOMER1,MFSD4B,MPV17,NDUFA4L2,NIPSNAP2,ORAI2,ORAI3,OSCP1,PEX5,PTEN,SCN9A,SFXN3,SLC10A3,SLC16A3,SLC25A11,SLC25A20,SLC25A45,SLC2A1,SLC30A9,SLC35B2,SLC35E2A,SLC35E2B,SLC39A9,TF |
| GO_MITOCHONDRION_ORGANIZATION | 0.0e+00 | 6.7e-06 | 375 | 528 | 19 | ATP5F1C,ATP5F1E,ATP5PD,BCL2L1,COA3,COX7A2,DYNLT1,HDAC6,HMGCL,MPV17,NDUFB1,NDUFB5,NIPSNAP2,OXA1L,SCO2,TAZ,TIMM8B,TIMMDC1,UQCRB |
| GO_EXOCYTOSIS | 0.0e+00 | 6.9e-06 | 375 | 900 | 25 | AGA,AGPAT2,ANXA2,AP1M1,APRT,C6orf120,CALM1,CD58,CEACAM8,CPNE1,CYBA,DGAT1,DNAJC5,DYNLT1,LAMTOR2,LIN7A,PPIA,PPP3CB,RAB33B,RAP2B,SNAPIN,TF,TGFB1,TMEM179B,TSG101 |
| GO_RIBOSE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 6.9e-06 | 375 | 192 | 12 | ACSBG1,APRT,ATP5F1C,ATP5F1E,ATP5PD,GSTZ1,PDHB,PPCS,SLC35B2,TAZ,TECR,TGFB1 |
| GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 0.0e+00 | 7.2e-06 | 375 | 1863 | 38 | ARHGAP35,ARHGAP39,ARHGDIA,BCL2L1,C18orf32,CALM1,CARD19,CPNE1,DGKQ,DUSP14,DUSP18,DYNLT1,EPM2A,EPOR,ERBB3,EZR,FADD,GPS2,IFIT5,LAMTOR2,LAMTOR4,LAMTOR5,LGALS1,PTEN,RELL2,RPS6KA6,SEC14L1,SLC35B2,SPPL3,TAF10,TAF7,TCP11,TF,TGFB1,TKFC,TSG101,WDR54,ZFAND6 |
| GO_DEPHOSPHORYLATION | 0.0e+00 | 7.2e-06 | 375 | 479 | 18 | CALM1,DLG2,DUSP14,DUSP18,ENSA,FAM122A,FIG4,G6PC,NT5DC1,PIP4P2,PPP1CA,PPP1R3D,PPP3CB,PRUNE1,PTEN,SPPL3,TGFB1,THTPA |
| GO_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 0.0e+00 | 8.0e-06 | 375 | 782 | 23 | ANXA2,ARRDC1,ATRAID,CHFR,EDEM1,EZR,FAM122A,FBXL14,FBXL8,FBXW4,FBXW5,HDAC6,MAN1B1,PTEN,RBX1,RNF187,RNF215,SPSB2,STUB1,TSG101,USP25,VPS25,ZNRF1 |
| GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 0.0e+00 | 8.0e-06 | 375 | 282 | 14 | ACSBG1,AGPAT2,APRT,ATP5F1C,ATP5F1E,ATP5PD,GSTZ1,NAXE,PDHB,PPCS,SLC35B2,TAZ,TECR,TGFB1 |
| GO_PURINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 1.0e-07 | 1.3e-05 | 375 | 206 | 12 | ACSBG1,APRT,ATP5F1C,ATP5F1E,ATP5PD,GSTZ1,PDHB,PPCS,SLC35B2,TAZ,TECR,TGFB1 |
| GO_PROTEIN_CATABOLIC_PROCESS | 1.0e-07 | 1.3e-05 | 375 | 938 | 25 | ANXA2,ARRDC1,ATRAID,CHFR,EDEM1,EZR,FAM122A,FBXL14,FBXL8,FBXW4,FBXW5,HDAC6,MAN1B1,PRSS16,PTEN,RBX1,RNF187,RNF215,SNX12,SPSB2,STUB1,TSG101,USP25,VPS25,ZNRF1 |
| GO_CARBOHYDRATE_METABOLIC_PROCESS | 1.0e-07 | 1.3e-05 | 375 | 620 | 20 | AKR7A2,CALM1,DCXR,DGKQ,G6PC,GALK1,GALT,MAN1B1,MIDN,NAGA,NDST2,OGDH,PDHB,PPP1CA,PPP1R3D,PTEN,SLC25A11,SLC2A1,TGFB1,TKFC |
| GO_ION_TRANSPORT | 1.0e-07 | 1.6e-05 | 375 | 1692 | 35 | ANXA2,ATP5F1C,ATP5F1E,ATP5PD,ATP6V0D1,CALM1,COX7A2,COX7C,CYBA,DLG2,G6PC,HOMER1,MFSD4B,NDUFA4L2,NIPSNAP2,ORAI2,ORAI3,PLEKHA8P1,PTEN,SCN9A,SCO2,SEC14L1,SLC10A3,SLC16A3,SLC25A11,SLC25A20,SLC25A45,SLC2A1,SLC30A9,SLC35B2,SLC39A9,STC1,TAF7,TF,XKR6 |
| GO_THIOESTER_METABOLIC_PROCESS | 1.0e-07 | 2.0e-05 | 375 | 105 | 9 | ACSBG1,DGAT1,GSTZ1,HMGCL,OGDH,OXSM,PDHB,PPCS,TECR |
| GO_MODIFICATION_DEPENDENT_MACROMOLECULE_CATABOLIC_PROCESS | 1.0e-07 | 2.2e-05 | 375 | 642 | 20 | ARRDC1,CHFR,EDEM1,FAM122A,FBXL14,FBXL8,FBXW4,FBXW5,HDAC6,MAN1B1,PTEN,RBX1,RNF187,RNF215,SPSB2,STUB1,TSG101,USP25,VPS25,ZNRF1 |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 2.0e-07 | 2.9e-05 | 375 | 1823 | 36 | ANXA2,ARL2BP,CALM1,CDKN1A,COX7A2,DGKQ,DLG2,DUSP14,DUSP18,ENSA,ERBB3,EZR,FAM122A,FAM20A,GPS2,GSTZ1,HDAC6,LAMTOR2,MIDN,NAB2,PRKACB,PTEN,RAP2B,RELL2,ROPN1L,RPS6KA6,SERTAD1,SPPL3,TADA3,TAF7,TAZ,TF,TGFB1,TSG101,VPS25,WDR54 |
| GO_GROWTH | 2.0e-07 | 3.0e-05 | 375 | 990 | 25 | ANXA2,BCL2L1,CDKN1A,CPNE1,CYBA,EYS,EZR,FAM122A,G6PC,GAS2,HDAC6,KCTD11,LAMTOR2,MT1E,N6AMT1,PPP3CB,PRMT2,PTEN,S1PR1,STC1,TAF10,TAL2,TGFB1,TSG101,TWF2 |
| GO_CELL_CYCLE | 3.0e-07 | 4.7e-05 | 375 | 1864 | 36 | ARL2,BCL2L1,CALM1,CDKN1A,CHFR,CNTD1,DYNLT1,ENSA,EZR,FBXL8,FBXW5,GAS2,JUND,KCTD11,LAMTOR2,LAMTOR4,LAMTOR5,PIWIL4,PLAGL1,PPP1CA,PRKACB,PRMT2,PTEN,RBX1,RING1,SERTAD1,TADA3,TAF10,TDRD12,TGFB1,TMEM250,TRAPPC12,TRNP1,TSG101,TUBB3,XPC |
| GO_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM | 3.0e-07 | 5.1e-05 | 375 | 499 | 17 | ATG16L2,ATP6V0D1,C19orf12,EPM2A,HDAC6,IFT88,LAMTOR2,LAMTOR4,LAMTOR5,RAB33B,SNAPIN,SNX32,STUB1,TBC1D25,TSG101,VPS16,VPS25 |
| GO_CATION_TRANSPORT | 4.0e-07 | 6.3e-05 | 375 | 1180 | 27 | ANXA2,ATP5F1C,ATP5F1E,ATP5PD,ATP6V0D1,CALM1,COX7A2,COX7C,CYBA,DLG2,HOMER1,MFSD4B,NDUFA4L2,NIPSNAP2,ORAI2,ORAI3,PTEN,SCN9A,SCO2,SEC14L1,SLC25A20,SLC25A45,SLC30A9,SLC39A9,STC1,TAF7,TF |
| GO_MACROMOLECULE_CATABOLIC_PROCESS | 4.0e-07 | 6.4e-05 | 375 | 1410 | 30 | ANXA2,ARRDC1,ATRAID,CALM1,CHFR,EDEM1,EZR,FAM122A,FBXL14,FBXL8,FBXW4,FBXW5,G6PC,HDAC6,MAN1B1,PPP1CA,PPP1R3D,PRSS16,PTEN,RBX1,RNF187,RNF215,SNX12,SPSB2,STUB1,TGFB1,TSG101,USP25,VPS25,ZNRF1 |
| GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 6.0e-07 | 9.0e-05 | 375 | 710 | 20 | AGA,AGPAT2,ANXA2,AP1M1,APRT,C6orf120,CD58,CEACAM8,CPNE1,CYBA,DGAT1,DNAJC5,DYNLT1,LAMTOR2,LGALS1,PPIA,RAP2B,TGFB1,TMEM179B,ZFPM1 |
| GO_SECRETION | 6.0e-07 | 9.4e-05 | 375 | 1680 | 33 | AGA,AGPAT2,ANXA2,AP1M1,APRT,ARL2,ARL2BP,C6orf120,CALM1,CD58,CEACAM8,CPNE1,CYBA,DGAT1,DNAJC5,DYNLT1,ENSA,ERBB3,EZR,LAMTOR2,LIN7A,MIDN,PPIA,PPP3CB,RAB33B,RAP2B,SLC2A1,SNAPIN,STC1,TF,TGFB1,TMEM179B,TSG101 |
| GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY | 7.0e-07 | 1.0e-04 | 375 | 96 | 8 | COA3,NDUFB1,NDUFB5,OXA1L,SCO2,TAZ,TIMMDC1,UQCRB |
| GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 7.0e-07 | 1.1e-04 | 375 | 1859 | 35 | ACSBG1,AGPAT2,APRT,ATP5F1C,ATP5F1E,ATP5PD,B3GALT6,BCAT2,CARS2,CHKB,COA3,DAD1,DALRD3,GALNT4,GPAA1,GSTZ1,MAN1B1,MRPS14,N6AMT1,NAXE,NDST2,NUDT14,OXA1L,PDHB,PGAP3,PIWIL4,PPCS,PPOX,PPP1CA,SLC35B2,SRD5A3,TAZ,TECR,TGFB1,ZFPM1 |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 8.0e-07 | 1.2e-04 | 375 | 1151 | 26 | AP1G2,AP1M1,AP4E1,CDKN1A,DLG2,DYNLRB1,EDEM1,HDAC6,HIKESHI,HMGCL,IFT22,IFT52,IFT88,MPV17,OXA1L,PEX5,RAB33B,SNAPIN,SNX15,TBC1D25,TGFB1,TIMM8B,TTC30A,VPS16,VPS25,ZFAND6 |
| GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 1.2e-06 | 1.6e-04 | 375 | 549 | 17 | AGA,AGPAT2,ANXA2,AP1M1,APRT,C6orf120,CD58,CEACAM8,CPNE1,CYBA,DGAT1,DNAJC5,DYNLT1,LAMTOR2,PPIA,RAP2B,TMEM179B |
| GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 1.2e-06 | 1.6e-04 | 375 | 1174 | 26 | ANXA2,ARL2,CALM1,CDKN1A,COMMD6,CPNE1,DLG2,DUSP14,DUSP18,ENSA,FAM122A,GPS2,HDAC6,LAMTOR5,MIDN,OXA1L,PDE6D,PPP1CA,PRMT2,PTEN,SIGIRR,STUB1,TAF7,TSG101,VPS25,ZFPM1 |
| GO_COFACTOR_BIOSYNTHETIC_PROCESS | 1.6e-06 | 2.1e-04 | 375 | 230 | 11 | ACSBG1,COQ10A,COQ5,CYBA,GSTZ1,ISCA2,NAXE,PDHB,PPCS,PPOX,TECR |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 1.6e-06 | 2.1e-04 | 375 | 1427 | 29 | ARHGAP35,ARRDC1,BCL2L1,BEND6,CALM1,CARD19,CPNE1,DLK2,DUSP14,DUSP18,EPM2A,ERBB3,EZR,FADD,GPS2,MIDN,NPHP4,PRKACB,PTEN,RBX1,RPS6KA6,SEC14L1,SIGIRR,STUB1,TGFB1,TKFC,TLE4,TSG101,VPS25 |
| GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 1.7e-06 | 2.2e-04 | 375 | 831 | 21 | ANXA2,ATP6V0D1,ATRAID,CHFR,EDEM1,EPM2A,EZR,FAM122A,HDAC6,IFT88,LAMTOR2,LAMTOR4,LAMTOR5,PPP1CA,PPP1R3D,PTEN,RBX1,SNX32,STUB1,TBC1D25,USP25 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 2.2e-06 | 2.8e-04 | 375 | 1698 | 32 | APRT,ATP5PD,ATP6V0D1,BCL2L1,CDKN1A,CYBA,DGKQ,EDEM1,ENSA,EZR,FADD,GPX4,HDAC6,HMGCL,HOMER1,JUND,LAMTOR2,LAMTOR4,LAMTOR5,LGALS1,MAN1B1,MPV17,PPP3CB,PRKACB,PTEN,SIGIRR,SLC10A3,SLC2A1,STC1,TGFB1,TWF2,ZNF580 |
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 2.4e-06 | 3.0e-04 | 375 | 1703 | 32 | ANXA2,ARHGAP35,ARRDC1,BCL2L1,BEND6,CALM1,CARD19,CDKN1A,CPNE1,DLK2,DUSP14,DUSP18,EPM2A,ERBB3,EZR,FADD,GPS2,NPHP4,PPP3CB,PRKACB,PTEN,RBX1,RPS6KA6,SEC14L1,SIGIRR,STUB1,TGFB1,TKFC,TLE4,TSG101,USP25,VPS25 |
| GO_MONOSACCHARIDE_METABOLIC_PROCESS | 2.6e-06 | 3.2e-04 | 375 | 292 | 12 | DCXR,DGKQ,G6PC,GALK1,GALT,MIDN,PDHB,PPP1CA,PPP1R3D,SLC25A11,SLC2A1,TKFC |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 2.6e-06 | 3.2e-04 | 375 | 1880 | 34 | ANXA2,ARL2BP,CALM1,CDKN1A,CHFR,DGKQ,DUSP14,DUSP18,ENSA,ERBB3,EZR,FAM122A,FAM20A,GPS2,HDAC6,LAMTOR2,NAB2,PRKACB,PTEN,RAP2B,RELL2,ROPN1L,RPS6KA6,SERTAD1,SPPL3,STUB1,TADA3,TAF7,TF,TGFB1,TSG101,VPS25,WDR54,ZNHIT1 |
| GO_RESPIRATORY_ELECTRON_TRANSPORT_CHAIN | 2.7e-06 | 3.3e-04 | 375 | 115 | 8 | COX7C,ETFRF1,NDUFB1,NDUFB5,TAZ,UQCR11,UQCRB,UQCRQ |
| GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 2.8e-06 | 3.3e-04 | 375 | 587 | 17 | CALM1,CDKN1A,DGKQ,DLG2,DUSP14,DUSP18,ENSA,EZR,FAM122A,GPS2,MIDN,PTEN,RPS6KA6,TAF7,TGFB1,TSG101,VPS25 |
| GO_CARBOHYDRATE_CATABOLIC_PROCESS | 2.9e-06 | 3.4e-04 | 375 | 198 | 10 | CALM1,DCXR,G6PC,GALK1,GALT,NAGA,OGDH,PPP1CA,PPP1R3D,TKFC |
| GO_ORGANIC_ACID_METABOLIC_PROCESS | 3.3e-06 | 3.7e-04 | 375 | 1164 | 25 | ABHD14B,ACSBG1,B3GALT6,BCAT2,CARS2,DALRD3,DCXR,G6PC,GALK1,GPX4,GSTZ1,HMGCL,MPST,N6AMT1,NDST2,OGDH,OXSM,PDHB,PRUNE1,SLC16A3,SLC2A1,SLC35B2,TECR,TGFB1,TYRP1 |
| GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 3.6e-06 | 4.0e-04 | 375 | 944 | 22 | ARL2,ARL2BP,CDKN1A,DLG2,EZR,GET1,GPAA1,HIKESHI,HMGCL,LAMTOR4,LAMTOR5,MPV17,NPHP4,OXA1L,PEX5,RAB33B,TGFB1,TIMM8B,TRAPPC12,TSG101,VPS25,ZFAND6 |
| GO_CATION_TRANSMEMBRANE_TRANSPORT | 4.1e-06 | 4.5e-04 | 375 | 879 | 21 | ANXA2,ATP5F1C,ATP5F1E,ATP5PD,ATP6V0D1,CALM1,COX7A2,COX7C,CYBA,DLG2,HOMER1,NDUFA4L2,NIPSNAP2,ORAI2,ORAI3,PTEN,SCN9A,SLC25A20,SLC25A45,SLC30A9,TF |
Num: 20 (Pathways: 21 DK: 2)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (2) | ALPK2, PXK |
| Light Kinase (4) | BRDT, ERN1, MAK, PRKCE |
| Non-kinase Count | 248 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 0.0e+00 | 2.0e-07 | 254 | 288 | 15 | BAK1,CLGN,CXCL8,ERN1,HSP90B1,HSPA5,KDELR3,NIBAN1,PDIA4,PPP1R15B,PREB,SDF2L1,TNFRSF10B,UBE2J2,UGGT2 |
| GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 0.0e+00 | 2.1e-06 | 254 | 201 | 12 | BAK1,CLGN,CXCL8,ERN1,HSP90B1,HSPA5,KDELR3,PPP1R15B,PREB,SDF2L1,UBE2J2,UGGT2 |
| GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 0.0e+00 | 2.1e-06 | 254 | 162 | 11 | BAK1,CLGN,CXCL8,ERN1,HSP90B1,HSPA5,KDELR3,PPP1R15B,PREB,SDF2L1,UGGT2 |
| GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 0.0e+00 | 2.5e-06 | 254 | 1930 | 33 | AGFG1,ARC,ARL4A,ARL4D,CNTN2,EHD1,EXPH5,FAM91A1,FLNB,FRMPD1,FZD5,HSP90B1,HSPA5,KDELR3,MAK,MFF,MX1,NVL,PIBF1,PREB,PRKCE,PYHIN1,RAB3IP,RAP1A,RAPGEF3,RIMS2,SAR1B,SPCS3,SRP19,SYTL2,UBE2J2,USO1,YWHAG |
| GO_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 0.0e+00 | 2.2e-05 | 254 | 122 | 9 | BAK1,CLGN,CXCL8,ERN1,HSP90B1,HSPA5,KDELR3,PPP1R15B,PREB |
| GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 0.0e+00 | 4.6e-05 | 254 | 1880 | 30 | BAK1,CCNH,ENPP2,ERN1,FXR2,FZD5,HSP90B1,HSPA5,IL15,IL24,INKA1,MAGEA2,MARVELD3,MAS1,NIBAN1,NLRP12,NRG1,PIAS1,PIBF1,PPP1R15B,PRKCE,RANBP9,RAP1A,RAPGEF3,SH3RF1,STRAP,TIPRL,TNFRSF10B,TRIM5,YWHAG |
| GO_POSITIVE_REGULATION_OF_TRANSPORT | 0.0e+00 | 4.6e-05 | 254 | 984 | 21 | ARC,BAK1,C2CD2L,CACNA1D,CADPS,CD47,CLEC4E,EHD1,EXPH5,FZD5,IL15,MFF,NLRP12,OXTR,PRKCE,RAP1A,RAPGEF3,SAR1B,SYTL2,UBE2J2,YWHAG |
| GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1.0e-07 | 6.4e-05 | 254 | 1823 | 29 | BAK1,CCNH,ENPP2,ERN1,FXR2,FZD5,HSP90B1,IL15,IL24,INKA1,MARVELD3,MAS1,MTMR9,NIBAN1,NLRP12,NRG1,PIBF1,PPP1R15B,PRKCE,RANBP9,RAP1A,RAPGEF3,SH3RF1,STRAP,SYTL2,TIPRL,TNFRSF10B,TRIM5,YWHAG |
| GO_INTRACELLULAR_TRANSPORT | 1.0e-07 | 7.8e-05 | 254 | 1741 | 28 | AGFG1,ARL4A,ARL4D,BBS7,COG5,EHD1,EXPH5,FAM91A1,FZD5,HSP90B1,HSPA5,KDELR3,MAK,MFF,PREB,RAB3IP,RAPGEF3,RIMS2,SAR1B,SEC22A,SPCS3,SRP19,SYTL2,UBE2J2,USO1,YIF1B,YKT6,YWHAG |
| GO_INTRACELLULAR_PROTEIN_TRANSPORT | 1.0e-07 | 1.0e-04 | 254 | 1151 | 22 | AGFG1,ARL4A,ARL4D,EHD1,EXPH5,FAM91A1,FZD5,HSP90B1,HSPA5,MAK,MFF,PREB,RAB3IP,RAPGEF3,RIMS2,SAR1B,SPCS3,SRP19,SYTL2,UBE2J2,USO1,YWHAG |
| GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 3.0e-07 | 2.1e-04 | 254 | 1208 | 22 | ABCC2,ATP6V1F,C2CD2L,COLEC12,CXCL8,ERN1,GJB3,GOT1,HSP90B1,HSPA5,IL15,IL24,MAS1,NR1I3,OR10H5,PRKCE,RAP1A,RAPGEF3,TRIM5,TRIM72,USO1,YWHAG |
| GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 4.0e-07 | 2.4e-04 | 254 | 1429 | 24 | AGFG1,AKIRIN2,ARHGAP25,ARHGAP26,BAK1,CACNA1D,EDN2,ERN1,FZD5,MAGEA2,MAS1,MTMR9,NLRP12,NRG1,NVL,PIBF1,PPP1R15B,PREB,PRKCE,RAP1A,RAPGEF3,RASGRP3,RGL3,TNFRSF10B |
| GO_PROTEIN_PHOSPHORYLATION | 4.0e-07 | 2.4e-04 | 254 | 1994 | 29 | ALPK2,BAK1,CCNH,ENPP2,ERN1,FXR2,FZD5,IL15,IL24,INKA1,MAK,MARVELD3,MAS1,NIBAN1,NLRP12,NRG1,OXTR,PIBF1,PPP1R15B,PRKCE,RANBP9,RAP1A,RAPGEF3,RASGRP3,SH3RF1,STRAP,TNFRSF10B,TRIM5,YWHAG |
| GO_REGULATION_OF_RESPONSE_TO_STRESS | 5.0e-07 | 2.4e-04 | 254 | 1559 | 25 | ADAMTS12,AKNA,BAK1,CD47,CLEC4E,CLNK,COLEC12,ERN1,EYA3,FUT8,FXR2,FZD5,HSP90B1,HSPA5,IL15,MARVELD3,MAS1,MUC19,NLRP12,PIAS1,PPP1R15B,PRKCE,PYHIN1,SH3RF1,TRIM5 |
| GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 5.0e-07 | 2.4e-04 | 254 | 1781 | 27 | AGFG1,AKIRIN2,ARC,ARHGAP25,ARHGAP26,BAK1,CACNA1D,EDN2,ERN1,FZD5,MAGEA2,MAS1,MTMR9,NLRP12,NRG1,NVL,PIBF1,PPP1R15B,PREB,PRKCE,PYHIN1,RAP1A,RAPGEF3,RASGRP3,RGL3,TNFRSF10B,TRIM5 |
| GO_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 5.0e-07 | 2.4e-04 | 254 | 1782 | 27 | ARC,ATAT1,CCNH,CLGN,COLEC12,EHD1,ELOB,KANK3,MFF,NDUFA1,NDUFB4,NDUFB9,NRG1,PIAS1,PREB,PRKCE,RAMAC,RANBP9,SAR1B,SF3B1,SHQ1,SRP19,SRSF12,STRAP,TMC8,TRIM72,USO1 |
| GO_RESPONSE_TO_BIOTIC_STIMULUS | 6.0e-07 | 2.4e-04 | 254 | 1567 | 25 | ABCC2,AKIRIN2,BAK1,CD47,CLEC4E,CLNK,COLEC12,CXCL8,FLNB,FZD5,HSP90B1,HSPA5,IL15,IL24,KRT6A,MUC19,MX1,NR1I3,PIAS1,PPP1R15B,PRKCE,PRSS3,PYHIN1,TRIM5,UPK1B |
| GO_SECRETION | 6.0e-07 | 2.4e-04 | 254 | 1680 | 26 | ABCC2,ARL4D,C2CD2L,CACNA1D,CADPS,CD47,CDC37L1,CLEC4E,EXPH5,FAM3C,FZD5,NLRP12,NRG1,OXTR,PDIA4,PGM2,PREB,PRKCE,PRSS3,RAP1A,RAPGEF3,RHOF,RIMS2,SYTL2,TRIM72,YKT6 |
| GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 7.0e-07 | 2.7e-04 | 254 | 1698 | 26 | ABCC2,AKIRIN2,ATP6V1F,BAK1,C2CD2L,COLEC12,CXCL8,ERN1,GJB3,GOT1,HSP90B1,HSPA5,IL15,IL24,MAS1,NR1I3,OR10H5,OXTR,PPP1R15B,PRKCE,RAP1A,RAPGEF3,TRIM5,TRIM72,USO1,YWHAG |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 9.0e-07 | 3.5e-04 | 254 | 1724 | 26 | AKIRIN2,BAK1,BBS7,CNTN2,ENPP2,ERN1,FXR2,FZD5,HSPA5,IL15,IL24,MAGEA2,MAS1,NIBAN1,NLRP12,NRG1,PIAS1,PIBF1,PPP1R15B,PRKCE,PYHIN1,RAP1A,RAPGEF3,SH3RF1,TNFRSF10B,TRIM5 |
| GO_REGULATION_OF_PHOSPHORYLATION | 1.1e-06 | 3.8e-04 | 254 | 1625 | 25 | BAK1,CCNH,ENPP2,ERN1,FXR2,FZD5,IL15,IL24,INKA1,MARVELD3,MAS1,NIBAN1,NLRP12,NRG1,PIBF1,PPP1R15B,PRKCE,RANBP9,RAP1A,RAPGEF3,SH3RF1,STRAP,TNFRSF10B,TRIM5,YWHAG |
Num: 6 (Pathways: 5 DK: 1)
The blue dots indicate the mean fold change, while the red dots indicate the overall means. The boxplots show the distribution of all the genes in the cluster. The kinases are highlighted with the lines.
| gene_type | info |
|---|---|
| Dark Kinase (1) | CDK14 |
| Light Kinase (3) | AATK, OXSR1, RIPK4 |
| Non-kinase Count | 171 |
| label | pval | fdr | signature | geneset | overlap | hits |
|---|---|---|---|---|---|---|
| GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 0e+00 | 1.2e-05 | 175 | 1703 | 25 | APCDD1L,CASTOR1,CD59,DEPTOR,DHRS3,FLCN,FNIP2,MNT,MVK,MYOZ2,NPHP3,NPY2R,NR1H3,NT5E,PTPN1,RASA3,RGS14,RGS6,RPH3AL,SPP1,TLE6,UBR5,VTN,WWOX,WWTR1 |
| GO_CELL_CELL_SIGNALING | 1e-07 | 2.8e-04 | 175 | 1665 | 22 | APCDD1L,CCNY,CDK14,FOXD1,GABRA3,IRS2,ITGB2,NPHP3,NPY2R,PLA2G6,PPFIA2,RGS14,RPH3AL,SHC3,SPP1,STXBP3,SV2C,TLE6,UBR5,WWOX,WWTR1,ZMYND8 |
| GO_LIPID_METABOLIC_PROCESS | 1e-07 | 2.8e-04 | 175 | 1405 | 20 | ACAD8,CUBN,DHRS3,FAXDC2,GGPS1,INPP4B,IRS2,MVK,NPC2,NR1H3,PIGZ,PIKFYVE,PLA2G6,PON2,SPP1,SYNJ2,TIPARP,UGT1A1,VAC14,WWOX |
| GO_NEGATIVE_REGULATION_OF_SIGNALING | 2e-07 | 2.8e-04 | 175 | 1427 | 20 | APCDD1L,CASTOR1,DEPTOR,DHRS3,FLCN,FNIP2,MNT,MYOZ2,NPHP3,NPY2R,NR1H3,PLA2G6,PTPN1,RASA3,RGS14,RGS6,RPH3AL,TLE6,WWOX,WWTR1 |
| GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 2e-07 | 2.8e-04 | 175 | 1724 | 22 | APAF1,CCND2,CCNY,CD28,CUL4B,FKBP1A,FLCN,FNIP2,HACE1,IFNGR1,ITGA2,MAGED1,NR1H3,OXSR1,PARP8,PLA2G6,PTPN1,PXYLP1,RNF217,TIPARP,VEGFC,VTN |